Conserved Protein Domain Family
SRP1

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COG5064: SRP1 
Karyopherin (importin) alpha [Intracellular trafficking and secretion]
Statistics
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PSSM-Id: 227396
Aligned: 4 rows
Threshold Bit Score: 743.633
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3122272    3 ASSRFIPEHRRQNYKGKGTFQADELRRRRETQQIEIRKQKREENLNKRRNL-------VDVQEPAEET-IPLEQDKENdl 74  fission yeast
19074976   1 -------MARSYMFDGK--T-TENRRKMREEQQVELRQQKKEELLNKKRNL--------SVSASAISNfIPMKEK----- 57  Encephalitozoon cun...
19113424   1 MESRYLSD-RRSRFKSKGVFKADELRRQREEQQIEIRKQKREESLNKRRNLnavlqndIDVEEEADQSqVQMEQQMKD-- 77  fission yeast
401119     8 STSKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFipp-tdgADSDEEDESS-VSADQQFYSql 85  baker's yeast
3122272   75 elELqlPDLLKALYSDDIEAQIQATAKFRKALSKETNPPIQKVIDAGVVPRFVEFL------------------SHENNL 136 fission yeast
19074976  58 ------------LFSNDLEQAHQGVYEFRSLLSVEDSPPIQPVIDSGCVPRFIELMdisfltssgmvmggipvsNIQRDM 125 Encephalitozoon cun...
19113424  78 --EF--PKLTADVMSDDIELQLGAVTKFRKYLSKETHPPIDQVIACGVVDRFVQFL------------------ESEHHL 135 fission yeast
401119    86 qqEL--PQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMr-----------------ENQPEM 146 baker's yeast
3122272  137 LKF------------EASWALTNVASGSSNQTHVVVEANAVPVFVSLLSSSEQDVREQAVWALGNIAGDSPMCRDHVLQC 204 fission yeast
19074976 126 PEFsvamdiinkirvEAAWVITNISSGTTQQTKVVIDCGAVPLLIQMLLDTNDAVLDQSVWALGNIAGDSEGMRDIILET 205 Encephalitozoon cun...
19113424 136 LQF------------EAAWALTNIASGTTDQTRIVVDSGAVPRFIQLLSSPEKDVREQVVWALGNIAGDSSACRDYVLGN 203 fission yeast
401119   147 LQL------------EAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQC 214 baker's yeast
3122272  205 GVLEPLLNIIE---SNRR-LSMLRNSTWTLSNMCRGKNPQPDWNSISQVIPVLSKLIYTLDEDVLVDALWAISYLSDGAN 280 fission yeast
19074976 206 GALDTVLGLLLklhESAIhIKIVRNLTWLLSNLNRGRNPPPSEQNMRKSLEILFKLINIRDPEVVSDAYWALSYIVDVSM 285 Encephalitozoon cun...
19113424 204 GVLQPLLNILQ---SSASdVSMLRNATWTLSNLCRGKNPPPNWSTISVAVPILAKLLYSEDVEIIVDACWAISYLSDGPN 280 fission yeast
401119   215 NAMEPILGLFN---SNKP--SLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQ 289 baker's yeast
3122272  281 EKIQAIIDAGIPRR---LVELLMH---------PSAQV----QTPALRSVGNIVTGDDVQTQVIINCGALSALLSL---L 341 fission yeast
19074976 286 ECSDIVLNSGTMGRthsLLEALTNrlvgmsysaEDAKIclcaISPIIRMIGNIVTGSDDQTSALIRMGFLKFFRPIfyrL 365 Encephalitozoon cun...
19113424 281 EKIGAILDVGCAPR---LVELLSS---------PSVNI----QTPALRSVGNIVTGTDAQTQIIIDCGALNAFPSL---L 341 fission yeast
401119   290 EAIQAVIDVRIPKR---LVELLSH---------ESTLV----QTPALRAVGNIVTGNDLQTQVVINAGVLPALRLL---L 350 baker's yeast
3122272  342 SSPRD-GVRKEACWTISNITAGNSSQIQYVIEANIIPPLIHLLTTADFKIQKEACWAISNATSGGARRP---DQ----IR 413 fission yeast
19074976 366 ENKKQpRLRKEICWTLSNITAGTVEHAKAVMDMDLAPLLIDSMSSYELFIRKEACWAVLNLMYHCNNLPsssDIkfewLK 445 Encephalitozoon cun...
19113424 342 SHQKE-NIRKEACWTISNITAGNTQQIQAIIESNLIPPLVHLLSYADYKTKKEACWAISNATSGGLGQP---DQ----IR 413 fission yeast
401119   351 SSPKE-NIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRP---DI----IR 422 baker's yeast
3122272  414 YLVEQGAIKPLCNLLACQDNKIIQVA---LDGIENILRVGELDRANNPDKINLYAVYVEDAGGMDLIHECQNSSNSEIYQ 490 fission yeast
19074976 446 ILMDNGFIDALESYLDVVPN-VPEMQcqiLDCFRYALNGGKQWELRYGKNP-IYEKMVE-ADIVDAIEGLQDSVDRTVSD 522 Encephalitozoon cun...
19113424 414 YLVSQGVIKPLCDMLNGSDNKIIQVA---LDAIENILKVGEMDRTMDLENINQYAVYVEEAGGMDMIHDLQSSGNNDIYL 490 fission yeast
401119   423 YLVSQGCIKPLCDLLEIADNRIIEVT---LDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYE 499 baker's yeast
3122272  491 KAYNIIEKFFGEE-DEIEE-LEPETVGDTFTFGTTQEPAGDFQ 531 fission yeast
19074976 523 KAYSIIVDFF----DGVDN------------------------ 537 Encephalitozoon cuniculi
19113424 491 KAYSIIEKYFSDE-DAVED-LAPETENGAFTFGNGPQAQGEFK 531 fission yeast
401119   500 KAYKIIETYFGEEeDAVDEtMAPQNAGNTFGFGSNVNQQFNFN 542 baker's yeast
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