2C2L,2F42


Conserved Protein Domain Family
CHIP_TPR_N
?
pfam18391: CHIP_TPR_N 
Click on image for an interactive view with Cn3D
CHIP N-terminal tetratricopeptide repeat domain
This is N-terminal tetratricopeptide repeat (TPR) domain found in C terminus of Hsp70 interacting proteins (CHIP). The TPR domain of CHIP binds directly to EEVD motifs located at the C termini of Hsc/Hsp70 and Hsp90.
Links
?
Statistics
?
PSSM-Id: 436460
Aligned: 44 rows
Threshold Bit Score: 73.776
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
2C2L_C       120 AKKKRWNSIEERRIHQESELHSYLTRLIAAERERELEECq-RNHEGHEDDGhIRAQQACIEAKHDKYMADMDELFSQVDE 198 house mouse
EDV26708     122 AKRKRWNELEQKRIRAQSDLYAYLKKLMFDDKERKIKNC-------KSDDSv---AVADVNKMYDSYSDQLENIFRKVDE 191
XP_019213108 129 AKKKRWNSMEERRINQESELQAYLTKLIHAEKKRELERCr-QKQEEKSDDSrVQQRLNEIHTKHDKYLSDLEELFCQVDE 207
KFV84051      89 AKKKRWNSIEEKRINQENELHSYLTKLIMAEKERELAEYrkTQQEESVDDSrSRAQLANIEAKHDKYLADMDELFSQVDE 168
KFR16440      89 AKKKRWNSIEEKRINQENELHSYLTKLIMAEKERGCEGL--SLGKRSPRTPrSSRPQGLLFQ--DKYLADMDELFSQVDE 164
XP_006005585 127 AKKKRWNSIEEKRINQENVLHAYLTKLILAEKERELEECklKQQEEGTEDSrAQAELAKIESKHEKYLIDMDELFSQVDE 206
2F42_A        22 AKKKRWNSIEEKRISQENELHAYLSKLILAEKEREL-----DDRVKQSDDSqNGGDISKMKSKHDKYLMDMDELFSQVDE 96  zebrafish
XP_007578064 127 AKKKRWNSIEEKRINQENELHAYLTKLILAEKEREL-----EEYKEKQDDNqNGGDAGKISSKHEKYLMEMEELFSQVDE 201
XP_019026552  95 AKKARWDAMEQRRIDQECELLANLKLHLSQDRDRRIA----EYMAGDLPPEeKDAECDWARQECEEQMRALCDAFARANE 170
GAN09857     116 ARKRKWEDDEAIRLEKENELLRYVKSLIEQDRAQQLAAV----------DPnDEEAIDTINYNIDERLSKVQHVFVQSKD 185

2C2L_C       199 KRKKR 203 house mouse
EDV26708     192 KHQKR 196
XP_019213108 208 KRKKR 212
KFV84051     169 KRKKR 173
KFR16440     165 KRKKR 169
XP_006005585 207 KRKRR 211
2F42_A        97 KRKKR 101 zebrafish
XP_007578064 202 KRKKR 206
XP_019026552 171 SLRPR 175
GAN09857     186 NASRR 190
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap