Conserved Protein Domain Family
Nucleoporin_FG2

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pfam15967: Nucleoporin_FG2 
Nucleoporin FG repeated region
Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.
Statistics
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PSSM-Id: 435043
Aligned: 5 rows
Threshold Bit Score: 658.666
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_005990604   1 MSGFSFGGGAG---------AGGGGFTLGAAAAaaaaaaaaagSNPGSTGGFSFGTLGAAP----AVATTTATTLGLGGG 67 
XP_011606140   1 MSGFNFGSGILgs------sTTGGGLSFGTAAS----------APATSSGGFSFGSALGAPa---APATSTTTALALGGG 61 
KAE8627430     2 ASGFSFGGAPAstttlnpaaGAAAPFSFGGTPAa---------SNTGTAGGLGFGAFG-------ATPTTQTATTGLGGG 65  tropical clawed...
XP_023805892   1 ---------------msgfnfgsgalgatnntgggfsfgaatsapaastsGFSFGTVLGTAaatpAS-TTTTASLGLGGN 64  Japanese medaka
XP_015197027   1 MSGFNFGSGGGlg-----stTAGGGFSLGAAT-----------SNPTGTGGFGLGTLGAATasgtATTTTTASSLSLGSA 64  spotted gar
XP_005990604  68 IFGQKPATGFTLGatNPGTTtaSSG---GLTLGAPAa-TSAASTGFSFGFNKPAGSATPFAL------PISSTSGSGLSL 137
XP_011606140  62 LFAQKPTGGFSFN--TPASS--AAAptaGLTLGTPA--SSAASTGFNFAFNKPTASATPFSLttvatpSSSAPAGAGLTF 135
KAE8627430    66 LFGAKPATGFTLG--GANTA--------------TAt-TTTASTGFSIGFNKPAGSATPFSL------PATTASSGGLSL 122 tropical clawed...
XP_023805892  65 PFGQKPTGGFSFN--TPTSSaaapat-gltlgGAPA--STAATTGFSLAFSKPTASASPFSLtt---sTASSTVGTGLSF 136 Japanese medaka
XP_015197027  65 VFPQKQATGFAFG--TPASGtaATGpvtGLTLGTPAatTTASTTGFTLGFNKPAASATPFSL-------VTSSAPGGLTL 135 spotted gar
XP_005990604 138 SSVLTSTAAPS-GATGFTL-NLGNAPatatTastglslgSTLS--------TLTGALFQNASTAapGLGQTALG------ 201
XP_011606140 136 GSVLTATAPQQpAASGFTLgGLGGAT----T--------TTVN--------SLGGGLFSSTIST--GLGQTTLGaggg-- 191
KAE8627430   123 SSALTSTQAA--GSSPFTL-NLGSTPatttAvstglslgGTLTglggtlggSLGGSLFQNPNPSvtALGQNTLGqntlgq 199 tropical clawed...
XP_023805892 137 GSILTSTAPQQpAATTFSL-GLGGSTastaA--------STVP--------SLGGSLFSSSVST---------------- 183 Japanese medaka
XP_015197027 136 GSSIASSTAQT-GSTGFAL-NLGGTNltsaPgstgltlgSTLA--------GLGSGLFQNTAAT--GLGLGALG------ 197 spotted gar
XP_005990604 202 ---------------------------------------LTLGA-----------------STTAPTS--VASEGLGGID 223
XP_011606140 192 ------------------------------------lnfGTLLA-----------------TSTAPTTapAPSIGLGGVD 218
KAE8627430   200 ntlgqntlgqntlgqntlgqntlgqntlgqntlgqntlgLGLNL-----------------GVVAPVSqvTANEGLGGLD 262 tropical clawed...
XP_023805892 184 ---------------------------------------G--LGqttlgagggltlgsllgTSTAASTapAPSIGLGGVD 222 Japanese medaka
XP_015197027 198 ------------------------------------------SA-----------------TSSAPVA--SAGLGLGGLD 216 spotted gar
XP_005990604 224 FSSSSDKKSDKASGTRPE-DSKALKDENLPPLICQDVENFQKFVKEQKQVQEEISRMSSKAMVKVQDDIKALKQLLSVAA 302
XP_011606140 219 FSTSSENKNDTSSGTSAL-DIKALKDENLPPVICQDVENFQKFVKDQKQVQEDISRMSSKAISRVQDDIKNLKQLLSVSA 297
KAE8627430   263 FGSSSDKKSDK-AGTRPE-DSKAFKDDNLPQLLCQDVENFQKFVKEQKQVQEEISRMSSKAMLKVQEDIKALRQLLSVAS 340 tropical clawed...
XP_023805892 223 FSTSSENKSDTLSGSS-EqDSKVLKDENLPPVICQDVENFQKFVKEQKQVQEEISRMSSKAISKVQDDIKNLKQLLSVNA 301 Japanese medaka
XP_015197027 217 FSTSSEKKSDK-SGARPE-DSKALKDENLPPVIYQDVDNFQKFVKEQKQVQEEISRMSSKAMLKVEEDIKSLKQLLSVCA 294 spotted gar
XP_005990604 303 SGLQRNTLAIDKLKVETAQELKFAEIALRTQKTPPGLQHENSAPADYFRALVEQFEVQLQQYRQQIEELENHLATQANSL 382
XP_011606140 298 SGLQRQGLAIDKLKLETAQELKNADIALRTQKTPPGLQHENTAPSDYFRSLVEQFEVQLQQYRQQIEELENHLTTQSSGN 377
KAE8627430   341 SGLQRNSLAIDKLKIETAQELKNAEIALRTQKTPPGLQHENTAPADYFHTLVQQFEVQLQQYRQQIEELENHLATQSNSS 420 tropical clawed...
XP_023805892 302 SGLQRQALAIDKLKQETAQELKNADIALRTQKTPPGLQHENTAPSDYFRSLVEQFEVQLQQYRQQIEELENHLTTQSSGS 381 Japanese medaka
XP_015197027 295 SGLQRNSLSIDKLKIETAQELKNADIALRTQKTPPGLQHENTAPADYFRGLVEQFEVQLQQYRQQIEELENHLTTQASSS 374 spotted gar
XP_005990604 383 HITPQDLSMAMQKLYQTFVALAAQLQSVHENVKILKEQYLGYRKTFLGDASDIFEARRAETKKWQSIPRVTTGPTPFSSI 462
XP_011606140 378 HITPQDLTLAMQKLYQTFVAQAAQLQSVHENVKILKHQYLSYRRAFLEDSTDVFESKRASNRKWQGTPKVTTGPAPFSSV 457
KAE8627430   421 HLSPQDLSLAMQKLYQTFVALAAQLQAVNENVKMLKEQYLGYRKAYLGDSADVFEARRAEAKKWQSAPRVTTGPTPFSNI 500 tropical clawed...
XP_023805892 382 HITPQDLTMAMQKLYQTFVAQAAQLQSVHENVKILKQQYLSYRRAFLEDTTDIFETKRASNRKWQSASRVTTGPAPFSTV 461 Japanese medaka
XP_015197027 375 HITPQDLSLAMQKLYHTFVAVAAQLQSVHENVKILKHQYLGYRKAFLEDSTDVFESKRAANKKWESAPRVTTGPAPFSTV 454 spotted gar
XP_005990604 463 PNAAAVAMAATLTQQQQPAT--------------------------------Gpqpslgvsfgtpfasgigtglqssglg 510
XP_011606140 458 PNAAAVAMAATLTQQQQPTP--------------------------------G--------------------------- 478
KAE8627430   501 PNAAAVAMAATLTQQQQPTTgfgsssafggntsgsstfgfgtankpsgslsaG--------------------------- 553 tropical clawed...
XP_023805892 462 PNAAAVAMAATLTQQQQPTP--------------------------------Gtqaplgagfgn---------------- 493 Japanese medaka
XP_015197027 455 PNAAAVAMAATLTQQQQPAT--------------------------------Gtqpslgvsfgapfgsgigtglqssglg 502 spotted gar
XP_005990604 511 ssslggFGSSSGFGSSNTGSSSFGFGST--SKPSG-SLSA------------GFGSSTTSGFNFSNPGITASAGLTFGVS 575
XP_011606140 479 ------FGGGPGFGGVGSGGSSFAFSST--SKPTGgSLSA------------GFGSSSSSGFNFSNPGINPSAGLTFGVS 538
KAE8627430   554 -----------------------------------------------------FGSTSTSGFNFSNPGINASAGLTFGVS 580 tropical clawed...
XP_023805892 494 ---pfasavgtslGSSTLGGFAGGPGFGgvGCAGSsFGFStaakpaggslsaGFGSTSSSGFNFSNPGINPSAGLTFGVS 570 Japanese medaka
XP_015197027 503 ssglgaFGSGPGFGSVTSGGSSFGFAPS--NKPSGgSLSA------------GFGSSSTSGFNFSNTGITASAGLTFGMP 568 spotted gar
XP_005990604 576 NPSASTFGTGqQQLIQLKKPPVGNKRGKR 604
XP_011606140 539 NQPVAGFSTG-GTLLQLKKPPAGNKRGKR 566
KAE8627430   581 NPSSTGFGTG-GQLLQLKKPPAGNKRGKR 608 tropical clawed frog
XP_023805892 571 NQPAVGFGAG-GPLLQLKKPPAGNKRGKR 598 Japanese medaka
XP_015197027 569 SAPATGFGAG-GPLLQLKKPPAGNKRGKR 596 spotted gar
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