6EOS,2DCM,1XFD,2GBI


Conserved Protein Domain Family
DPPIV_N

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pfam00930: DPPIV_N 
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Dipeptidyl peptidase IV (DPP IV) N-terminal region
This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.
Statistics
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PSSM-Id: 395744
Aligned: 34 rows
Threshold Bit Score: 273.424
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6EOS_C 173 QGSGTFLFQAGS--------GIYHVKDGGPQGFTQQPLRP-----------NLVETSCPN------------IRMDPKLC 221 human
Q8A028  96 SPDGDKLLIATK--------TTPIYRHSYTAVHYIYPLKRndkg---vttnNIIERLSDGg-----------PQQVPVFS 153 Bacteroides thetaiota...
Q7UXN0 145 SADGRYLLVYNN--------TRRVWRQHTRGDYWLRDLSD-----------DSPEATWRKigged---apdaKTMFATFA 202 Pirellula sp.
Q8P3V8 126 APDAHALLF------------------PLGGELYLYDLRKtg--------sAAVRQLTHGe----------gFATDAKLS 169 Xanthomonas campestri...
Q9FNF6 103 NSKMRFIVV------------------PLPAGVYMKDLSSsp--------nPELIVPSSPt----------sPIIDPRLS 146 thale cress
Q7NEK8 135 SPDGKRVLV------------------SLSGRLFVYARPE-----------GRVQELATSp----------gTVLDPKFS 175 Gloeobacter violaceus
Q8A2Q1 106 WADKPQMLL------------------KVSGKYIVYDFEN-----------NRIVSTLKLk----------dKAANEDYC 146 Bacteroides thetaiota...
2DCM_A  89 DAGRGLVVL------------------FTQGGLVGFDMLA-----------RKVTYLFDTn----------eETASLDFS 129 Porphyromonas gingiva...
Q8P843 103 SADGGNSVTATTlpferfayAQEDGRADGAMEFEIGDTSWrctltnyqcapVAATAQPRPrgfgvvrdpavpADATPRRS 182 Xanthomonas campestri...
Q8P500 141 KAATLAPKVRLT--------ADGRYRFEIRDTDVICDVRA------------ACSKVYASe-----------KAEPGVLS 189 Xanthomonas campestri...
6EOS_C 222 PAdPDWIAFIHSNDIWIS---NIVTReeRRLTYVHNElanmeEDARSAGVATFVLQEE-FDRYSGYWWCPKAEttpsggk 297 human
Q8A028 154 PD-GTMIAFVRDNNIFLV---KLLYGn-SESQVTEDGk----QNMVLNGIPDWVYEEE-FGFNRALEFSADNT------- 216 Bacteroides thetaiota...
Q7UXN0 203 PD-GQSIAFVRDNDLYLE---DCETGdlQMVAGSDDP-------KLISGTFDWVYEEE-LGLRNGFRFSPNSQ------- 263 Pirellula sp.
Q8P3V8 170 PK-GGFVSFVRARNLWVI---DLASG--KQLQLTRDG-----SDTIGNGVAEFVADEE-MDRHTGYWWAPDDS------- 230 Xanthomonas campestri...
Q9FNF6 147 PN-GLFLAYVRESELHVL---NLLKn--QTQQLTSGAn----GSTLSHGLAEYIAQEE-MDRRNGYWWSLDSK------- 208 thale cress
Q7NEK8 176 PD-GTQVSYVLNADIYAI---DLAAG--KERQITSGG-----NGQVSNGLAEFVAQEE-MGRFSGYWWSPDSR------- 236 Gloeobacter violaceus
Q8A2Q1 147 VA-NGNVAYTVNNNLYVN---EQ--------AIT-DE-----PEGIVCGQS--VHRNE-FGINKGTFWSPKGN------- 198 Bacteroides thetaiota...
2DCM_A 130 PV-GDRVAYVRNHNLYIArggKLGEGmsRAIAVTIDG-----TETLVYGQA--VHQRE-FGIEKGTFWSPKGS------- 193 Porphyromonas gingiva...
Q8P843 183 PD-GAWEVVANGWNLQLR---RVADG--QSTRLSSDG------------------RAEdFYDLESVAWSPDSQ------- 231 Xanthomonas campestri...
Q8P500 190 PD-KTREAFIRNWNLWVR---ELATG--KETQLTRDGv---eNFGYATDNAGWQHSD-----NAIVAWSPDSR------- 248 Xanthomonas campestri...
6EOS_C 298 ilRILYEENDESEVEIIHVTSPMLETR---------RADSFR---YPKTGTAN-PKVTFKMSEImidAEGRIIdvidkeL 364 human
Q8A028 217 --MIAFIRFDESEVPSYSFPMFAGEAPqitplkdypGEYTYK---YPKAGYPN-SKVEVRTYDI---KSHVTR------T 281 Bacteroides thetaiota...
Q7UXN0 264 --KLAFWQLDSNGVPIQTMIDNTSEry--------aKAIEFA---YPKVGQTN-SAAKVGVWDR---TSKKTV------W 320 Pirellula sp.
Q8P3V8 231 --AIAFARIDESAVPIQKRPEVYADHT---------EVIDQR---YPQAGQPN-VTVQLGVIVP---RASATP------Q 286 Xanthomonas campestri...
Q9FNF6 209 --FIAYTEVDSSQIPLFRIMHQGKRSv---------GSEAQEdhaYPFAGALN-STLRLGVVSS---AGGGKTtw---mN 270 thale cress
Q7NEK8 237 --WVAYEQADARPVEIWRPADPARPEA---------SPHAQH---YPRPGKAN-VEVRLGVVGA---DGGRT-------T 291 Gloeobacter violaceus
Q8A2Q1 199 --LLAFYRMDESMVTQYPLVDITARVG---------EVNNVR---YPMAGMTS-HQVKVGVYNP---STGKTI------Y 254 Bacteroides thetaiota...
2DCM_A 194 --CLAFYRMDQSMVKPTPIVDYHPLEA---------ESKPLY---YPMAGTPS-HHVTVGIYHL---ATGKTV------Y 249 Porphyromonas gingiva...
Q8P843 232 --HLAVYRVRPGYARRVTRVEAAPPGGgq------pVVHTQL---YPKPGDA--VDVERPVLFA---LDGS--------R 287 Xanthomonas campestri...
Q8P500 249 --KIATFQQDQRKTGDMYLVSTKLgh---------pELQSWK---YPLAGDKDvTMIERVIIDVptaSVVRLKlppdqhR 314 Xanthomonas campestri...
6EOS_C 365 IQPFEILFEGVEYIARAGW--TPEgk-----yAWSILLDRSQTRLQIVLIspELfipveddvmerqRLIESVPDSvtpli 437 human
Q8A028 282 MKLP---IDADGYIPRIRF--TKDas-----kLAVMTLNRHQDRFDLYFA--DP------------RSTLCKLVL----- 332 Bacteroides thetaiota...
Q7UXN0 321 LDLPG--DPRENYIAAVDW--LPSefthanerLLIQQLNRKQNQNHVYLC--DV------------ETGHCVNIH----- 377 Pirellula sp.
Q8P3V8 287 WIDLG--KQADIYLARVDW---RDaq-----rLTFQRQSRDQKTLQLIEA--TL------------ASGKQRVLI----- 337 Xanthomonas campestri...
Q9FNF6 271 LVCGGRGNTEDEYLGRVNW--LPGn------vLIVQVLNRSQSKLKIISF--DI------------NTGQGNVLL----- 323 thale cress
Q7NEK8 292 WVDWD--RERYPYLATVKWdkGGP--------LTLVVQDRLQQQEAVLTA--DT------------DTGRTAVLL----- 342 Gloeobacter violaceus
Q8A2Q1 255 LNAG---DPTDRYFTNISW--SPDek-----sIYLIELNRDQNHAVLCQY--DA------------TTGKLLSKLl---- 306 Bacteroides thetaiota...
2DCM_A 250 LQTG---EPKEKFLTNLSW--SPDen-----iLYVAEVNRAQNECKVNAY--DA------------ETGRFVRTLf---- 301 Porphyromonas gingiva...
Q8P843 288 REVDTALFGNPYALSPLQW--RSDsr-----sVSFEYVQRGFQRMRVIAV--DA------------QTGRAHVAV----- 341 Xanthomonas campestri...
Q8P500 315 STLCDDVSCSPGLWDDVKW--APDsk-----tLAFASTSRFHKQVWLRIA--DA------------STGAVRTAF----- 368 Xanthomonas campestri...
6EOS_C 438 iyEETTDIWI----NIHDIFHVFpq---sHEEEIEFIFASEcKTGFRHLYKITSILKEskykrssgglpapsdfkcpIKe 510 human
Q8A028 333 --RDESPYYI----KENVFDNIK-------FYPETFSLLSE-RDGFSHLYWYSMGGNL-------------------IK- 378 Bacteroides thetaiota...
Q7UXN0 378 --TEVSDAWVrhlrELHWLPGTVfkndasDNSSPRLLWLSE-RSGWQHIEAIEIPAPDslee-----------esnlPSr 443 Pirellula sp.
Q8P3V8 338 --TETSPTWV----PLTNDLRFL-------K-DGRFLWNSE-RSGYEHLYVASEDGTT-------------------LT- 382 Xanthomonas campestri...
Q9FNF6 324 --TEESDTWV----TLHDCFTPLekv-psSRGSGGFIWASE-RTGFRHLYLYESDGTC-------------------LG- 375 thale cress
Q7NEK8 343 --TESDPAWL----NLDQQTPRW------LGDGSGFLWTSE-RQGAPQLELRDRQGQF-------------------VRl 390 Gloeobacter violaceus
Q8A2Q1 307 --EETHPKYV----EPQHPIVFL------PWDSSKFIYQSQ-RDGYNHLYLCDLTSSLkgewksdaa-ggkhieyipTK- 371 Bacteroides thetaiota...
2DCM_A 302 --VETDKHYV----EPLHPLTFL------PGSNNQFIWQSR-RDGWNHLYLYDTTGRL-------------------IR- 348 Porphyromonas gingiva...
Q8P843 342 --GEDARTFVyadrSFRHDVE---------GRGDEILWISE-RDGWRHLYLFDGRSGKv------------------KR- 390 Xanthomonas campestri...
Q8P500 369 --DETAKTYY----ESGQVAANWa----yLPGSNEAVWFSE-RSDWGQLYLYDLQTGKp------------------KR- 418 Xanthomonas campestri...
6EOS_C 511 eiAITSGEWEVlgrhGSNIQVDEVRRLVYFEGTKDS----PLEHHLYVVSYVn------PGEVTRLTDRGYSH-SCCISQ 579 human
Q8A028 379 --KVTNGKYEV----KDFLGYDATDGSFYYTSNEES----PLRKAVYKIDKK--------GKKTKLSQREGTN-TPLFSK 439 Bacteroides thetaiota...
Q7UXN0 444 itPVTGGSWDV----ISIAAVAKDGSHIDFIASPEQ----PSQRALYRVSLEqglsgqlATTPERISPDEGGTfSYSVSP 515 Pirellula sp.
Q8P3V8 383 --PLTSGAWVV----DALLAVDEQAGLVYFAGSKDS----PTQTHIYAVALG-------GGAIEKRSASNGTH-AASFAN 444 Xanthomonas campestri...
Q9FNF6 376 --AITSGEWMV----EQIAGVNEPMSLVYFTGTLDG----PLETNLYCAKLEagn--tsRCQPMRLTHGKGKH-IVVLDH 442 thale cress
Q7NEK8 391 lvAPTIGYVPE----KSDLAVDETRREVYFQAGA-T----PTAVGLWRVSLD-------GGEPVALTDRPGQH-LAVYAR 453 Gloeobacter violaceus
Q8A2Q1 372 --QLTEGKWLV----GDILGFNAKRKEVIFQGVDGT------GSNNFAVNVNtgk-cslPFSFRSIT--EGEH-NGMLSA 435 Bacteroides thetaiota...
2DCM_A 349 --QVTKGEWEV----TNFAGFDPKGTRLYFESTEAS----PLERHFYCIDIK-------GGKTKDLTPESGMH-RTQLSP 410 Porphyromonas gingiva...
Q8P843 391 --QLTRGAWIV----RDVLRVDDAQRRIWFTASGMDagkdPYYRQLYSVDFD-------GRQLTRLTHSDADH-DVAIAP 456 Xanthomonas campestri...
Q8P500 419 --AITSGEGNV----TELLRVDPVSRTAWFVGVGKVpgvdPYYQQLWKVSLD-------GGAPVLLTPEAADH-SIALSP 484 Xanthomonas campestri...
6EOS_C 580 HCDFFISKYSNQKNPH 595 human
Q8A028 440 SMKYYMNKFSNLDTPM 455 Bacteroides thetaiotaomicron
Q7UXN0 516 TADYALESWSDFNSAP 531 Pirellula sp.
Q8P3V8 445 NASVYVDTWSNTTTQP 460 Xanthomonas campestris pv. campestris
Q9FNF6 443 QMKNFVDIHDSVDSPP 458 thale cress
Q7NEK8 454 NFSLVARSFTDSGAMP 469 Gloeobacter violaceus
Q8A2Q1 436 SGSYLIDRYSTPTLPR 451 Bacteroides thetaiotaomicron
2DCM_A 411 DGSAIIDIFQSPTVPR 426 Porphyromonas gingivalis W83
Q8P843 457 DGQHYVDTYSRPDLPP 472 Xanthomonas campestris pv. campestris
Q8P500 485 DGARFVDTYSTTLTPP 500 Xanthomonas campestris pv. campestris
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