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HR1: Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
The HR1 domain, also called the ACC (anti-parallel coiled-coil) finger domain or Rho-binding domain ...
View in Cn3D
HR1_ROCK1: Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rho-associated coiled-coil containing protein kinase 1
ROCK1 is a serine/threonine kinase and is preferentially expressed in the liver, lung, spleen, teste...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
HR1_ROCK2: Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rho-associated coiled-coil containing protein kinase 2
ROCK2 is a serine/threonine protein kinase and was the first identified target of activated RhoA. It...
HR1_PKN3_3: Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N3
PKN3, also called PKNbeta, is a serine/threonine protein kinase that is activated by the Rho family ...
HR1_PKN1_3: Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1
PKN1, also called PKNalpha or Protein-kinase C-related kinase 1 (PRK1), is a serine/threonine protei...
HR1_PKN2_3: Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
PKN2, also called PKNgamma or Protein-kinase C-related kinase 2 (PRK2), is a serine/threonine protei...
HR1_Rhophilin-2: Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rhophilin-2
Rhophilin-2 is a scaffolding protein that functions as an effector of the Rho family of small GTPase...
HR1_Rhophilin-1: Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rhophilin-1
Rhophilin-1 is a scaffolding protein that functions as an effector of the Rho family of small GTPase...
HR1_PKN3_2: Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N3
HR1_PKN2_2: Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2
HR1_PKN1_2: Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1
HR1_FBP17: Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Formin Binding Protein 17
FBP17, also called FormiN Binding Protein 1 (FNBP1), is involved in dynamin-mediated endocytosis. It...
HR1_CIP4_FNBP1L: Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of vertebrate Cdc42-Interacting Protein 4 and FormiN Binding Protein 1-Like
CIP4 and FNBP1L are Cdc42 effectors that bind Wiskott-Aldrich syndrome protein (WASP) and function i...
HR1_Ste20-like: Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Schizosaccharomyces pombe Ste20-like proteins
This group is composed of predominantly uncharacterized fungal proteins, which contain two known dom...
HR1_ROCK: Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rho-associated coiled-coil containing protein kinase
ROCK is also referred to as Rho-associated kinase or simply as Rho kinase. It is a serine/threonine ...
View in Cn3D SuperfamilySuperfamily MembersPubMed
HR1_PKN_3: Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
PKN, also called Protein-kinase C-related kinase (PRK), is a serine/threonine protein kinase that ca...
HR1_Rhophilin: Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rhophilin
Rhophilins are scaffolding proteins that function as effectors of the Rho family of small GTPases. V...
HR1_PKN_2: Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
HR1_PKN_1: First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N
HR1_PKC-like_1_fungi: First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of fungal Protein Kinase C-like proteins
This subfamily is composed of fungal PKC-like proteins including Pkc1p from Saccharomyces cerevisiae...
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