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Accession: PRJNA170188 ID: 170188

Mus musculus (house mouse)

Gene expression profiling of NK cells isolated from the pancreas of BDC TCR expressing NOD mice before or after Treg ablation by DTR. Also, NK cells cultured in vitro with activating cytokines IL12 and IL-18 with or without regulatory TGFb.

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Following Treg ablation in the BDC/NOD.Foxp3-DTR strain, NK cells produce IFNg and accumulate to higher percentage and number. More...
AccessionPRJNA170188; GEO: GSE39197
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsSitrin J et al., "Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2.", J Exp Med, 2013 Jun 3;210(6):1153-65
SubmissionRegistration date: 9-Jul-2012
CBDM, Microbiology and Immunobiology, Harvard Medical School
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets3
GEO Data Details
ParameterValue
Data volume, Spots1032954
Data volume, Processed Mbytes18
Data volume, Supplementary Mbytes173

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  • Mus musculus
    Mus musculus
    Gene expression profiling of NK cells isolated from the pancreas of BDC TCR expressing NOD mice before or after Treg ablation by DTR. Also, NK cells cultured in vitro with activating cytokines IL12 and IL-18 with or without regulatory TGFb.
    BioProject
  • BioProject Links for GEO DataSets (Select 4946) (1)
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