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Accession: PRJNA951382 ID: 951382

Effect of mechanical ventilation and mechanical ventilationon with positive end expiratory pressure(PEEP) application on diaphragmatic dysfunction in rabbits (rabbit)

See Genome Information for Oryctolagus cuniculus
To investigate the effect of mechanical ventilation and mechanical ventilationon with PEEP application on diaphragmatic dysfunction, we established a model of mechanical ventilation on New Zealand rabbit, in which rabbits in the experimental group were ventilated with/without PEEP application for 48 hours continuously Overall design: Comparative gene expression profiling analysis of RNA-seq data on diaphragm between the control group and the mechanical ventilation group
AccessionPRJNA951382; GEO: GSE228739
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismOryctolagus cuniculus[Taxonomy ID: 9986]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus; Oryctolagus cuniculus
PublicationsShen W et al., "Cellular senescence contributes to mechanical ventilation-induced diaphragm dysfunction by upregulating p53 signalling pathways.", BMC Pulm Med, 2023 Dec 14;23(1):509
SubmissionRegistration date: 2-Apr-2023
School of Pharmaceutical Sciences, Jilin University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments9
Publications
PubMed1
PMC1
Other datasets
BioSample9
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes8
SRA Data Details
ParameterValue
Data volume, Gbases50
Data volume, Mbytes16234

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