National Center for
Biotechnology Information

7VPX: The cryo-EM structure of the human pre-A complex

PDB ID:

MMDB ID:

229670

PDB Deposition Date:

2021/10/18

Updated in MMDB:

2024/05

Experimental Method:

electron microscopy

Resolution:

3 Å

Source Organism:

unidentified adenovirus▼

Taxonomy	Molecule
unidentified adenovirus	I, K
Homo sapiens	B, D, J, H, 1, 2, 3, 4, 5, A, C, E, F, G, a, b, c, d, e, f, g, L, O, m, h, k, M, n, l, i, N, j, 6

Similar Structures:

Biological Unit for 7VPX: 35-meric; determined by author

Molecular Components in 7VPX
Label	Count	Molecule
Proteins (31 molecules)
B	1	Splicing Factor 3A Subunit 2
D	1	Splicing Factor 1
J	1	Dnaj Homolog Subfamily C Member 8
1	1	Splicing Factor 3B Subunit 1
2	1	Splicing Factor 3B Subunit 2
3	1	Splicing Factor 3B Subunit 3
4	1	Splicing Factor 3B Subunit 4
5	1	Splicing Factor 3B Subunit 5
A	1	Splicing Factor 3A Subunit 1
C	1	Splicing Factor 3A Subunit 3
E	1	Probable Atp-dependent RNA Helicase Ddx46
F	1	U2 Small Nuclear Ribonucleoprotein A'
G	1	U2 Small Nuclear Ribonucleoprotein B''
a i	2	Small Nuclear Ribonucleoprotein SM D2
b m	2	Small Nuclear Ribonucleoprotein F
c l	2	Small Nuclear Ribonucleoprotein E
d n	2	Small Nuclear Ribonucleoprotein G
e j	2	Small Nuclear Ribonucleoprotein SM D3
f k	2	Small Nuclear Ribonucleoprotein-associated Proteins B and B'
g h	2	Small Nuclear Ribonucleoprotein SM D1
O	1	U1 Small Nuclear Ribonucleoprotein 70 KDA
M	1	U1 Small Nuclear Ribonucleoprotein a
N	1	U1 Small Nuclear Ribonucleoprotein C
6	1	PHD Finger-like Domain-containing Protein 5A
Nucleotides(4 molecules)
H	1	U2 Snrna
I	1	Pre-mrna
K	1	5SS
L	1	U1 Snrna
Chemicals and Non-standard biopolymers (7 molecules)
1	6	ZINC ION
2	1	spliceostatin A (form II)

* Click molecule labels to explore molecular sequence information.

Citing MMDB