NCBI
National Center for
Biotechnology Information
Search
7UFC:
Human CYP3A4 bound to an inhibitor
PDB ID:
7UFC
Download
MMDB ID:
218440
PDB Deposition Date:
2022/3/22
Updated in MMDB:
2023/10
Experimental Method:
x-ray diffraction
Resolution:
2.35 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 7UFC: dimeric; determined by author
Molecular Components in 7UFC
Label
Count
Molecule
Proteins (2 molecules)
A
A_1
2
Cytochrome P450 3A4
(Gene symbol:
CYP3A4
)
Chemicals and Non-standard biopolymers (4 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FE
2
2
(2R)-3-phenyl-2-({(2S)-3-phenyl-2-[3-(pyridin-3-yl)propanamido]propyl}sulfanyl)-N-[2-(pyridin-3-yl)ethyl]propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303