6CCY: Crystal structure of Akt1 in complex with a selective inhibitor

PDB ID: 6CCYDownload
MMDB ID: 161514
PDB Deposition Date: 2018/2/7
Updated in MMDB: 2018/05
Experimental Method:
x-ray diffraction
Resolution: 2.18  Å
Source Organism:
Similar Structures:
Biological Unit for 6CCY: monomeric; determined by author and by software (PISA)
Molecular Components in 6CCY
Label Count Molecule
Protein (1 molecule)
1
Rac-alpha Serine/threonine-protein Kinase,piftide
(Gene symbol: AKT1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(5R)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1H-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one(5R)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1H-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303