5J2U: Tubulin-MMAF complex

PDB ID: 5J2UDownload
MMDB ID: 192040
PDB Deposition Date: 2016/3/30
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 5J2U: octameric; determined by author and by software (PISA)
Molecular Components in 5J2U
Label Count Molecule
Proteins (6 molecules)
2
Tubulin Alpha-1b Chain
Molecule annotation
2
Tubulin Beta-2b Chain
Molecule annotation
1
Stathmin-4
Molecule annotation
1
Tubulin Beta-2b Chain
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
GH
2
Monomethyl auristatin F (MMAF)
1
2
N-METHYLVALINEN-METHYLVALINE
2
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
3
5
MAGNESIUM IONMAGNESIUM ION
4
1
CALCIUM IONCALCIUM ION
5
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
6
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303