4NPV: Crystal structure of human PDE1B bound to inhibitor 7A (6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine)

PDB ID: 4NPVDownload
MMDB ID: 121511
PDB Deposition Date: 2013/11/22
Updated in MMDB: 2014/07
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 4NPV: monomeric; determined by author and by software (PISA)
Molecular Components in 4NPV
Label Count Molecule
Protein (1 molecule)
1
Calcium/calmodulin-dependent 3',5'-cyclic Nucleotide Phosphodiesterase 1B
(Gene symbol: PDE1B)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303