4MXZ: Src M314L T338M double mutant bound to kinase inhibitor bosutinib

PDB ID: 4MXZDownload
MMDB ID: 115692
PDB Deposition Date: 2013/9/26
Updated in MMDB: 2013/12
Experimental Method:
x-ray diffraction
Resolution: 2.582  Å
Source Organism:
Similar Structures:
Biological Unit for 4MXZ: monomeric; determined by author and by software (PISA)
Molecular Components in 4MXZ
Label Count Molecule
Protein (1 molecule)
1
Proto-oncogene Tyrosine-protein Kinase SRC
(Gene symbol: SRC)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303