4BTY: Crystal structure of human vascular adhesion protein-1 in complex with pyridazinone inhibitors

PDB ID: 4BTYDownload
MMDB ID: 116015
PDB Deposition Date: 2013/6/19
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 4BTY: dimeric; determined by author and by software (PISA)
Molecular Components in 4BTY
Label Count Molecule
Proteins (2 molecules)
2
Membrane Primary Amine Oxidase
(Gene symbol: AOC3)
Molecule annotation
Chemicals and Non-standard biopolymers (23 molecules)
1
12
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
2
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
COPPER (II) IONCOPPER (II) ION
5
4
CALCIUM IONCALCIUM ION
6
2
5-[4-(4-methylpiperazin-1-yl)phenylamino]-2-(4-chlorophenyl)-6-(1H-1,2,4-triazol-5-yl)-3(2H)-pyridazinone5-[4-(4-methylpiperazin-1-yl)phenylamino]-2-(4-chlorophenyl)-6-(1H-1,2,4-triazol-5-yl)-3(2H)-pyridazinone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303