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3VHE:
Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor
PDB ID:
3VHE
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MMDB ID:
94853
PDB Deposition Date:
2011/8/24
Updated in MMDB:
2011/11
Experimental Method:
x-ray diffraction
Resolution:
1.55 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 3VHE: monomeric; determined by author and by software (PISA)
Molecular Components in 3VHE
Label
Count
Molecule
Protein (1 molecule)
A
1
Vascular Endothelial Growth Factor Receptor 2
(Gene symbol:
KDR
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-{2-fluoro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[3-(trifluoromethyl)phenyl]urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303