3LXS: Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (WRR483)

PDB ID: 3LXSDownload
MMDB ID: 85589
PDB Deposition Date: 2010/2/25
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 3LXS: monomeric; determined by author and by software (PISA)
Molecular Components in 3LXS
Label Count Molecule
Protein (1 molecule)
1
Cruzain
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
(Z)-N-(5-GUANIDINO-1-OXO-1-(5-PHENYL-1-(PHENYLSULFONYL)PENT-1-EN-3-YLAMINO)PENTAN-2-YL)-4-METHYLPIPERAZINE-1-CARBOXAMID E(Z)-N-(5-GUANIDINO-1-OXO-1-(5-PHENYL-1-(PHENYLSULFONYL)PENT-1-EN-3-YLAMINO)PENTAN-2-YL)-4-METHYLPIPERAZINE-1-CARBOXAMID E
2
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
4
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303