3LPG: Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)urea

PDB ID: 3LPGDownload
MMDB ID: 86236
PDB Deposition Date: 2010/2/5
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.425  Å
Source Organism:
Similar Structures:
Biological Unit for 3LPG: tetrameric; determined by author and by software (PISA)
Molecular Components in 3LPG
Label Count Molecule
Proteins (4 molecules)
4
Beta-glucuronidase
(Gene symbol: uidA)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-[(6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]urea3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-[(6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303