3JWR: Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with 3-isobutyl-1-methylxanthine (IBMX) and PDE6 gamma-subunit inhibitory peptide 70-87

PDB ID: 3JWRDownload
MMDB ID: 77373
PDB Deposition Date: 2009/9/18
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 2.994  Å
Source Organism:
Similar Structures:
Biological Unit for 3JWR: dimeric; determined by author and by software (PISA)
Molecular Components in 3JWR
Label Count Molecule
Proteins (2 molecules)
1
Cgmp-specific 3',5'-cyclic Phosphodiesterase Catalytic Domain, Cone Cgmp-specific 3',5'-cyclic Phosphodiesterase Subunit Alpha Chimera
(Gene symbol: PDE5A)
Molecule annotation
1
Retinal ROD Rhodopsin-sensitive Cgmp 3',5'-cyclic Phosphodiesterase Subunit Gamma
(Gene symbol: PDE6G)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ZINC IONZINC ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
3
3-ISOBUTYL-1-METHYLXANTHINE3-ISOBUTYL-1-METHYLXANTHINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303