3JUS: Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with econazole

PDB ID: 3JUSDownload
MMDB ID: 80462
PDB Deposition Date: 2009/9/15
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 3JUS: dimeric; determined by author
Molecular Components in 3JUS
Label Count Molecule
Proteins (2 molecules)
2
Lanosterol 14-alpha Demethylase
(Gene symbol: CYP51A1)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
14
alpha-D-glucopyranosealpha-D-glucopyranose
2
2
1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
3
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
4
2
1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303