2Z81: Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

PDB ID: 2Z81Download
MMDB ID: 59996
PDB Deposition Date: 2007/8/30
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2Z81: monomeric; determined by author and by software (PISA)
Molecular Components in 2Z81
Label Count Molecule
Protein (1 molecule)
1
Toll-like Receptor 2, Variable Lymphocyte Receptor B
(Gene symbol: Tlr2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
5
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
1
alpha-D-mannopyranosealpha-D-mannopyranose
4
1
(2R)-3-{[(2S)-3-HYDROXY-2-(PALMITOYLAMINO)PROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE(2R)-3-{[(2S)-3-HYDROXY-2-(PALMITOYLAMINO)PROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303