2CW6: Crystal Structure of Human HMG-CoA Lyase: Insights into Catalysis and the Molecular Basis for Hydroxymethylglutaric Aciduria

PDB ID: 2CW6Download
MMDB ID: 36455
PDB Deposition Date: 2005/6/17
Updated in MMDB: 2005/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2CW6: dimeric; determined by author and by software (PISA)
Molecular Components in 2CW6
Label Count Molecule
Proteins (2 molecules)
2
Hydroxymethylglutaryl-coa Lyase, Mitochondrial
(Gene symbol: HMGCL)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
1
3-HYDROXYPENTANEDIOIC ACID3-HYDROXYPENTANEDIOIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303