1NVX: Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS

PDB ID: 1NVXDownload
MMDB ID: 22445
PDB Deposition Date: 2003/2/4
Updated in MMDB: 2021/11
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 1NVX: trimeric; determined by author and by software (PISA)
Molecular Components in 1NVX
Label Count Molecule
Proteins (3 molecules)
2
Transforming Protein P21/h-ras-1
(Gene symbol: HRAS)
Molecule annotation
1
SON of Sevenless Protein Homolog 1
(Gene symbol: SOS1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
3
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303