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1EF3:
FIDARESTAT BOUND TO HUMAN ALDOSE REDUCTASE
PDB ID:
1EF3
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MMDB ID:
15228
PDB Deposition Date:
2000/2/6
Updated in MMDB:
2007/10
Experimental Method:
x-ray diffraction
Resolution:
2.8 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1EF3: dimeric; determined by author
Molecular Components in 1EF3
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Aldose Reductase
(Gene symbol:
AKR1B1
)
Chemicals and Non-standard biopolymers (4 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
(2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303