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Conserved domains on  [gi|2052103028|ref|XP_041909894|]
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GTP:AMP phosphotransferase AK3, mitochondrial isoform X2 [Corvus kubaryi]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11995178)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
11-205 5.55e-93

Adenylate kinase;


:

Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 271.10  E-value: 5.55e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  11 IMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDR-YNWLLD 89
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCkNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  90 GFPRTVAQAEALDK----ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVqtvlpesqeltfkirtQGI 165
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKV----------------PGK 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2052103028 166 DDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKK 205
Cdd:pfam00406 145 DDVTGEPLVQRSDDNEETVKKRLETYHKQTKPLIDYYKKK 184
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
11-205 5.55e-93

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 271.10  E-value: 5.55e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  11 IMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDR-YNWLLD 89
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCkNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  90 GFPRTVAQAEALDK----ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVqtvlpesqeltfkirtQGI 165
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKV----------------PGK 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2052103028 166 DDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKK 205
Cdd:pfam00406 145 DDVTGEPLVQRSDDNEETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 8-214 2.03e-92

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 270.46  E-value: 2.03e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLD-RYNW 86
Cdd:COG0563     2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDcANGF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  87 LLDGFPRTVAQAEALDK-----ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVqtvlpesqeltfkir 161
Cdd:COG0563    82 ILDGFPRTVAQAEALDEllaelGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKV--------------- 146

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2052103028 162 tQGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGT 214
Cdd:COG0563   147 -EGVCDKCGGELVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
adk PRK00279
adenylate kinase; Reviewed
 7-228 1.21e-90

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 266.25  E-value: 1.21e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   7 LRAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLD-RYN 85
Cdd:PRK00279    1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDcKNG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  86 WLLDGFPRTVAQAEALDKECH-----IDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVqtvlpesqeltfki 160
Cdd:PRK00279   81 FLLDGFPRTIPQAEALDEMLKelgikLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKV-------------- 146

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2052103028 161 rtQGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET-NKIWPHIYAFLQ 228
Cdd:PRK00279  147 --EGKCDVCGEELIQRADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSiDEVFADILKALG 213
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 8-228 2.11e-88

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 260.24  E-value: 2.11e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYN-- 85
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDNEng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  86 WLLDGFPRTVAQAEALDK--ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVqtvlpesqeltfkirtQ 163
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKV----------------P 144

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2052103028 164 GIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGT-ETNKIWPHIYAFLQ 228
Cdd:TIGR01351 145 GCDDCTGELLVQREDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 8-216 3.27e-84

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 249.08  E-value: 3.27e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYN-W 86
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKgF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  87 LLDGFPRTVAQAEALDKECH----IDTVIDLDVPFETIKCRLTARWIHPASGRVYNLefsppkvqtvlpesqeltfkirt 162
Cdd:cd01428    81 ILDGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL----------------------- 137

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2052103028 163 qGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 216
Cdd:cd01428   138 -GKDDVTGEPLSQRSDDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
11-205 5.55e-93

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 271.10  E-value: 5.55e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  11 IMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDR-YNWLLD 89
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCkNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  90 GFPRTVAQAEALDK----ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVqtvlpesqeltfkirtQGI 165
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKV----------------PGK 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2052103028 166 DDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKK 205
Cdd:pfam00406 145 DDVTGEPLVQRSDDNEETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 8-214 2.03e-92

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 270.46  E-value: 2.03e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLD-RYNW 86
Cdd:COG0563     2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDcANGF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  87 LLDGFPRTVAQAEALDK-----ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVqtvlpesqeltfkir 161
Cdd:COG0563    82 ILDGFPRTVAQAEALDEllaelGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKV--------------- 146

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2052103028 162 tQGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGT 214
Cdd:COG0563   147 -EGVCDKCGGELVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
adk PRK00279
adenylate kinase; Reviewed
 7-228 1.21e-90

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 266.25  E-value: 1.21e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   7 LRAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLD-RYN 85
Cdd:PRK00279    1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDcKNG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  86 WLLDGFPRTVAQAEALDKECH-----IDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVqtvlpesqeltfki 160
Cdd:PRK00279   81 FLLDGFPRTIPQAEALDEMLKelgikLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKV-------------- 146

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2052103028 161 rtQGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET-NKIWPHIYAFLQ 228
Cdd:PRK00279  147 --EGKCDVCGEELIQRADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSiDEVFADILKALG 213
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 8-228 2.11e-88

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 260.24  E-value: 2.11e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYN-- 85
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDNEng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  86 WLLDGFPRTVAQAEALDK--ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVqtvlpesqeltfkirtQ 163
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKV----------------P 144

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2052103028 164 GIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGT-ETNKIWPHIYAFLQ 228
Cdd:TIGR01351 145 GCDDCTGELLVQREDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 8-216 3.27e-84

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 249.08  E-value: 3.27e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYN-W 86
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKgF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  87 LLDGFPRTVAQAEALDKECH----IDTVIDLDVPFETIKCRLTARWIHPASGRVYNLefsppkvqtvlpesqeltfkirt 162
Cdd:cd01428    81 ILDGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL----------------------- 137

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2052103028 163 qGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 216
Cdd:cd01428   138 -GKDDVTGEPLSQRSDDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
PLN02674 PLN02674
adenylate kinase
 5-208 6.37e-57

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 181.62  E-value: 6.37e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   5 PLLRAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLD-R 83
Cdd:PLN02674   30 PDKRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPScQ 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  84 YNWLLDGFPRTVAQAEALD-----KECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKVQtvlpesqeltf 158
Cdd:PLN02674  110 KGFILDGFPRTVVQAQKLDemlakQGAKIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVP----------- 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2052103028 159 kirtqGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLL 208
Cdd:PLN02674  179 -----GVDDVTGEPLIQRKDDTAAVLKSRLEAFHKQTEPVIDYYAKKGVV 223
PRK14530 PRK14530
adenylate kinase; Provisional
 8-231 9.95e-48

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 156.87  E-value: 9.95e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKK-----TEVGIlAKSYIDQGKLIPDDIMTQLMLNELKGLD 82
Cdd:PRK14530    5 RILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRANKQMDisdmdTEYDT-PGEYMDAGELVPDAVVNEIVEEALSDAD 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  83 RYnwLLDGFPRTVAQAEALDKECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPPKvqtvlpesqeltfkirT 162
Cdd:PRK14530   84 GF--VLDGYPRNLEQAEYLESITDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPE----------------E 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028 163 QGIDDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET-NKIWPHIYAFLQTRL 231
Cdd:PRK14530  146 EGVCDECGGELIQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTpDEVWADIQDAIDDAT 215
adk PRK02496
adenylate kinase; Provisional
 8-216 3.76e-41

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 139.11  E-value: 3.76e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYN-W 86
Cdd:PRK02496    3 RLIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPDAANgW 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  87 LLDGFPRTVAQAEALDK---ECH--IDTVIDLDVPFETIKCRLTARwihpasgrvynlefsppkvqtvlpesqeltfkir 161
Cdd:PRK02496   83 ILDGFPRKVTQAAFLDEllqEIGqsGERVVNLDVPDDVVVERLLAR---------------------------------- 128

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2052103028 162 tqgidditgeplvQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 216
Cdd:PRK02496  129 -------------GRKDDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQS 170
PRK14527 PRK14527
adenylate kinase; Provisional
 8-216 5.08e-37

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 128.75  E-value: 5.08e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVI-MGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYNW 86
Cdd:PRK14527    7 KVVIfLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPVRV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  87 LLDGFPRTVAQAEALDK-----ECHIDTVIDLDVPFETIKCRLTARwihpasgrvynlefsppkvqtvlpESQEltfkir 161
Cdd:PRK14527   87 IFDGFPRTLAQAEALDRlleelGARLLAVVLLEVPDEELIRRIVER------------------------ARQE------ 136

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2052103028 162 tqgidditgeplvQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 216
Cdd:PRK14527  137 -------------GRSDDNEETVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGT 178
PRK14526 PRK14526
adenylate kinase; Provisional
 7-216 5.49e-37

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 129.20  E-value: 5.49e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   7 LRAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLD-RYN 85
Cdd:PRK14526    1 MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKnNDN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  86 WLLDGFPRTVAQAEALDKECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLefsppkvqtvlpesqeLTFKIRTQGI 165
Cdd:PRK14526   81 FILDGFPRNINQAKALDKFLPNIKIINFLIDEELLIKRLSGRRICKSCNNIFNI----------------YTLPTKEKGI 144

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2052103028 166 DDITGEPLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 216
Cdd:PRK14526  145 CDVCKGDLYQRKDDKEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKD 195
PRK14531 PRK14531
adenylate kinase; Provisional
 8-210 9.98e-37

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 127.62  E-value: 9.98e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYNWL 87
Cdd:PRK14531    4 RLLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLKALNSGGWL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  88 LDGFPRTVAQAEALDKechidTVIDLDVPFETIkcrltarwihpasgrvynlefsppkvqtVLPESQeltfkirtqgiDD 167
Cdd:PRK14531   84 LDGFPRTVAQAEALEP-----LLEELKQPIEAV----------------------------VLLELD-----------DA 119

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2052103028 168 ITGEPLVQ--RDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKS 210
Cdd:PRK14531  120 VLIERLLArgRADDNEAVIRNRLEVYREKTAPLIDHYRQRGLLQS 164
PLN02842 PLN02842
nucleotide kinase
 10-202 1.81e-36

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 134.22  E-value: 1.81e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  10 VIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLD--RYNWL 87
Cdd:PLN02842    1 MISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDakEKGWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  88 LDGFPRTVAQAEALDK-ECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNLEFSPpkvqtvlPESQELtfKIRtqgid 166
Cdd:PLN02842   81 LDGYPRSFAQAQSLEKlKIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFP-------PESEEI--KAR----- 146

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2052103028 167 ditgepLVQRDDDKPETVSKRLQAYDAQTKPVLEYY 202
Cdd:PLN02842  147 ------LITRPDDTEEKVKARLQIYKKNAEAILSTY 176
PLN02459 PLN02459
probable adenylate kinase
 10-211 3.29e-36

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 128.81  E-value: 3.29e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  10 VIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELK-GLDR--YNW 86
Cdd:PLN02459   33 VFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEaGEEEgeSGF 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  87 LLDGFPRTVAQAEALDKECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYNL--------EFSPPKVQTVLPESQELTF 158
Cdd:PLN02459  113 ILDGFPRTVRQAEILEGVTDIDLVVNLKLREEVLVEKCLGRRICSECGKNFNVadidlkgeDGRPGIVMPPLLPPPECAS 192

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2052103028 159 KirtqgidditgepLVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSF 211
Cdd:PLN02459  193 K-------------LITRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEF 232
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 11-214 4.57e-35

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 123.64  E-value: 4.57e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  11 IMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKK-TEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDR-YNWLL 88
Cdd:TIGR01359   4 VLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKREgSENGSLIESYIKEGKIVPSEVTVELLKKAIQEDGSsKKFLI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  89 DGFPRTVAQAEA----LDKECHIDTVIDLDVPFETIKCRLTARwiHPASGRVynlefsppkvqtvlpesqeltfkirtqg 164
Cdd:TIGR01359  84 DGFPRNEENLEAweklMDNKVNFKFVLFFDCPEETMIKRLLKR--GQTSGRV---------------------------- 133

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2052103028 165 idditgeplvqrdDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGT 214
Cdd:TIGR01359 134 -------------DDNIETLKKRFRTYNEETLPIIEHFENKGKVKEINAE 170
PRK14532 PRK14532
adenylate kinase; Provisional
 10-213 1.45e-34

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 122.24  E-value: 1.45e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  10 VIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLM---LNELKGLDryNW 86
Cdd:PRK14532    4 ILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIeerLPEAEAAG--GA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  87 LLDGFPRTVAQAEALDK-----ECHIDTVIDLDVPFETIKCRLTARWihpasgrvynlefsppkvqtvlpesqeltfkiR 161
Cdd:PRK14532   82 IFDGFPRTVAQAEALDKmlasrGQKIDVVIRLKVDDEALIERIVKRF--------------------------------E 129

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2052103028 162 TQGidditgeplvqRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSG 213
Cdd:PRK14532  130 EQG-----------RPDDNPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDG 170
PRK13808 PRK13808
adenylate kinase; Provisional
 7-213 7.06e-34

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 124.23  E-value: 7.06e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   7 LRAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYN- 85
Cdd:PRK13808    1 MRLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAANg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  86 WLLDGFPRTVAQAEALD-----KECHIDTVIDLDVPfetiKCRLTARwihpasgrvynlefsppkVQTVLPESQEltfki 160
Cdd:PRK13808   81 FILDGFPRTVPQAEALDallkdKQLKLDAVVELRVN----EGALLAR------------------VETRVAEMRA----- 133

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2052103028 161 rtqgiddiTGEPLvqRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSG 213
Cdd:PRK13808  134 --------RGEEV--RADDTPEVLAKRLASYRAQTEPLVHYYSEKRKLLTVDG 176
PRK14528 PRK14528
adenylate kinase; Provisional
 8-216 1.97e-33

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 119.35  E-value: 1.97e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   8 RAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYN-W 86
Cdd:PRK14528    3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNgF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  87 LLDGFPRTVAQAEALD---KECH--IDTVIDLDVPFETIKCRLTARWIhpasgrvynlefsppkvqtvlpesqeltfkir 161
Cdd:PRK14528   83 LLDGFPRTVEQADALDallKNEGksIDKAINLEVPDGELLKRLLGRAE-------------------------------- 130

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2052103028 162 tqgiddITGeplvqRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET 216
Cdd:PRK14528  131 ------IEG-----RADDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGS 174
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 7-231 7.96e-32

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 116.44  E-value: 7.96e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028   7 LRAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNEL-KGLDRY- 84
Cdd:PTZ00088    7 LKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIaKVTDDCf 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  85 -NWLLDGFPRTVAQAEALDKECHIDTVIDLDVPFETIKCRLTARWIHPASGRVYN---LEFSPPKVQTVLPEsqeltfki 160
Cdd:PTZ00088   87 kGFILDGFPRNLKQCKELGKITNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNiahIRSDPYDMPPILPP-------- 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2052103028 161 rtQGIDDITGEP-LVQRDDDKPETVSKRLQAYDAQTKPVLEYYRKKGL-LKSFSGTETNKIWPHIYAFLQTRL 231
Cdd:PTZ00088  159 --ADCEGCKGNPkLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNENCnLVDFEITRGLRDFDDFYRIVLQRL 229
PRK14529 PRK14529
adenylate kinase; Provisional
 10-127 2.15e-31

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 115.20  E-value: 2.15e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  10 VIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYNWLLD 89
Cdd:PRK14529    4 LIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQDGKNGWLLD 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2052103028  90 GFPRTVAQAEALDKECH-----IDTVIDLDVPFETIKCRLTAR 127
Cdd:PRK14529   84 GFPRNKVQAEKLWEALQkegmkLDYVIEILLPREVAKNRIMGR 126
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 11-208 1.36e-27

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 104.13  E-value: 1.36e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  11 IMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQlMLNE--LKGLDRYN-WL 87
Cdd:TIGR01360   8 IVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLD-LLKDamVAALGTSKgFL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  88 LDGFPRTVAQAEALDKEC-HIDTVIDLDVPFETIKCRLTARwiHPASGRVynlefsppkvqtvlpesqeltfkirtqgid 166
Cdd:TIGR01360  87 IDGYPREVKQGEEFERRIgPPTLVLYFDCSEDTMVKRLLKR--AETSGRV------------------------------ 134

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2052103028 167 ditgeplvqrdDDKPETVSKRLQAYDAQTKPVLEYYRKKGLL 208
Cdd:TIGR01360 135 -----------DDNEKTIKKRLETYYKATEPVIAYYETKGKL 165
AAA_17 pfam13207
AAA domain;
12-140 2.07e-24

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 94.23  E-value: 2.07e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  12 MGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTevGILAKSYIDQGKLIPDDIMTQLMLNELKGLD-RYNWLLDG 90
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERIAEEAgEGGVIVDG 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2052103028  91 FPRTVAQAEALD-------KECHIDTVIDLDVPFETIKCRLTARwihPASGRVY-NLE 140
Cdd:pfam13207  79 HPRIKTPAGYLPglpvevlRELKPDAIILLEADPEEILERRLKD---RTRGRDDdSEE 133
PLN02200 PLN02200
adenylate kinase family protein
 11-223 3.97e-24

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 96.50  E-value: 3.97e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  11 IMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKKTEVGILAKSYIDQGKLIPDDIMTQLMLNELKGLDRYNWLLDG 90
Cdd:PLN02200   48 VLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSDNNKFLIDG 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  91 FPRTVAQAEALDK--ECHIDTVIDLDVPFETIKCRLTARwihpASGRVynlefsppkvqtvlpesqeltfkirtqgiddi 168
Cdd:PLN02200  128 FPRTEENRIAFERiiGAEPNVVLFFDCPEEEMVKRVLNR----NQGRV-------------------------------- 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2052103028 169 tgeplvqrdDDKPETVSKRLQAYDAQTKPVLEYYRKKGLLKSFSGTET-NKIWPHI 223
Cdd:PLN02200  172 ---------DDNIDTIKKRLKVFNALNLPVIDYYSKKGKLYTINAVGTvDEIFEQV 218
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 127-178 3.88e-13

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 61.71  E-value: 3.88e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2052103028 127 RWIHPASGRVYNLEFSPPKVqtvlpesqeltfkirtQGIDDITGEPLVQRDD 178
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKV----------------EGVCDVCGGELVQRDD 36
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 10-48 2.25e-07

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 49.34  E-value: 2.25e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2052103028  10 VIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRDNMQKK 48
Cdd:TIGR02173   4 TISGPPGSGKTTVAKILAEKLSLKLISAGDIFRELAAKM 42
PRK04182 PRK04182
cytidylate kinase; Provisional
 7-43 5.31e-07

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 48.26  E-value: 5.31e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2052103028   7 LRAVIMGPPGSGKGTVSARIIKHFGMKHLSSGDLLRD 43
Cdd:PRK04182    1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRE 37
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 11-40 7.22e-07

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 47.48  E-value: 7.22e-07
                          10        20        30
                  ....*....|....*....|....*....|
gi 2052103028  11 IMGPPGSGKGTVSARIIKHFGMKHLSSGDL 40
Cdd:cd02020     4 IDGPAGSGKSTVAKLLAKKLGLPYLDTGGI 33
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 10-130 1.90e-05

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 43.40  E-value: 1.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  10 VIMGPPGSGKGTVSARIIKHFGMKHLsSGDLLR--DNMQKKTevgilaksyidQGklIP-DDIMTQLMLNELKGlDRYNW 86
Cdd:cd02021     3 VVMGVSGSGKSTVGKALAERLGAPFI-DGDDLHppANIAKMA-----------AG--IPlNDEDRWPWLQALTD-ALLAK 67

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2052103028  87 LLDGFPRTVAQAEAL--------DKECHI--DTVIDLDVPFETIKCRLTARWIH 130
Cdd:cd02021    68 LASAGEGVVVACSALkriyrdilRGGAANprVRFVHLDGPREVLAERLAARKGH 121
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
10-167 1.95e-05

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 43.75  E-value: 1.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  10 VIMGPPGSGKGTVSARIIKHFGMKHLSSgDLLRdnmqkKTevgiLAKSYIDQGKLIPD------DIMTQLMLNELK-Gld 82
Cdd:COG0645     3 LVCGLPGSGKSTLARALAERLGAVRLRS-DVVR-----KR----LFGAGLAPLERSPEatartyARLLALARELLAaG-- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  83 rYNWLLD-GFPR--TVAQAEALDKECHID-TVIDLDVPFETIKCRLTARW----IHPASGRVYN--LEFSPPkvqtvLPE 152
Cdd:COG0645    71 -RSVILDaTFLRraQREAFRALAEEAGAPfVLIWLDAPEEVLRERLEARNaeggDSDATWEVLErqLAFEEP-----LTE 144

                         170
                  ....*....|....*
gi 2052103028 153 SQELTFKIRTQGIDD 167
Cdd:COG0645   145 DEGFLLVVDTSGLEE 159
AAA_18 pfam13238
AAA domain;
10-127 8.41e-04

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 38.18  E-value: 8.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052103028  10 VIMGPPGSGKGTVSARIikhfgMKHLSSGDLLRDNMQKKtEVGILAKSYIDQGKLIPDDIMTQLmLNELKGLDRY----N 85
Cdd:pfam13238   2 LITGTPGVGKTTLAKEL-----SKRLGFGDNVRDLALEN-GLVLGDDPETRESKRLDEDKLDRL-LDLLEENAALeeggN 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2052103028  86 WLLDGFPrtvAQAEA-LDKECHidtVIDLDVPFETIKCRLTAR 127
Cdd:pfam13238  75 LIIDGHL---AELEPeRAKDLV---GIVLRASPEELLERLEKR 111
PRK11860 PRK11860
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
11-42 8.91e-04

bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;


Pssm-ID: 237003 [Multi-domain]  Cd Length: 661  Bit Score: 40.03  E-value: 8.91e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2052103028  11 IMGPPGSGKGTVSARIIKHFGMKHLSSGDLLR 42
Cdd:PRK11860  447 IDGPTASGKGTVAARVAEALGYHYLDSGALYR 478
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
13-38 4.09e-03

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 37.31  E-value: 4.09e-03
                          10        20
                  ....*....|....*....|....*.
gi 2052103028  13 GPPGSGKGTVSARIIKHFGMKHLSSG 38
Cdd:COG0283     7 GPAGSGKSTVAKALAKRLGYHYLDTG 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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