neuronal PAS domain-containing protein 3 isoform X39 [Mus musculus]
List of domain hits
Name | Accession | Description | Interval | E-value | |||||
PAS_3 | pfam08447 | PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
239-326 | 1.66e-18 | |||||
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. : Pssm-ID: 430001 [Multi-domain] Cd Length: 89 Bit Score: 80.85 E-value: 1.66e-18
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PAS | smart00091 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
48-106 | 1.59e-11 | |||||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. : Pssm-ID: 214512 Cd Length: 67 Bit Score: 60.49 E-value: 1.59e-11
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bHLH_SF super family | cl00081 | basic Helix Loop Helix (bHLH) domain superfamily; bHLH proteins are transcriptional regulators ... |
1-22 | 1.17e-08 | |||||
basic Helix Loop Helix (bHLH) domain superfamily; bHLH proteins are transcriptional regulators that are found in organisms from yeast to humans. Members of the bHLH superfamily have two highly conserved and functionally distinct regions. The basic part is at the amino end of the bHLH that may bind DNA to a consensus hexanucleotide sequence known as the E box (CANNTG). Different families of bHLH proteins recognize different E-box consensus sequences. At the carboxyl-terminal end of the region is the HLH region that interacts with other proteins to form homo- and heterodimers. bHLH proteins function as a diverse set of regulatory factors because they recognize different DNA sequences and dimerize with different proteins. The bHLH proteins can be divided to cell-type specific and widely expressed proteins. The cell-type specific members of bHLH superfamily are involved in cell-fate determination and act in neurogenesis, cardiogenesis, myogenesis, and hematopoiesis. The actual alignment was detected with superfamily member cd19732: Pssm-ID: 469605 Cd Length: 78 Bit Score: 52.70 E-value: 1.17e-08
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MSCRAMM_ClfA super family | cl41352 | MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
332-491 | 2.55e-04 | |||||
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif. The actual alignment was detected with superfamily member NF033609: Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.90 E-value: 2.55e-04
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KinE super family | cl47428 | Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
50-309 | 5.58e-03 | |||||
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]; The actual alignment was detected with superfamily member COG5809: Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 39.96 E-value: 5.58e-03
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Name | Accession | Description | Interval | E-value | |||||
PAS_3 | pfam08447 | PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
239-326 | 1.66e-18 | |||||
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. Pssm-ID: 430001 [Multi-domain] Cd Length: 89 Bit Score: 80.85 E-value: 1.66e-18
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PAS | cd00130 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
227-309 | 1.89e-13 | |||||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction. Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 66.89 E-value: 1.89e-13
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PAS | smart00091 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
48-106 | 1.59e-11 | |||||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. Pssm-ID: 214512 Cd Length: 67 Bit Score: 60.49 E-value: 1.59e-11
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PAS | cd00130 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
54-106 | 3.67e-10 | |||||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction. Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 57.64 E-value: 3.67e-10
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PAS | pfam00989 | PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
48-106 | 7.79e-10 | |||||
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain can bind gases (O2, CO and NO), FAD, 4-hydroxycinnamic acid and NAD+ (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://0-doi-org.brum.beds.ac.uk/10.1093/femsre/fuab043). Pssm-ID: 395786 [Multi-domain] Cd Length: 113 Bit Score: 57.04 E-value: 7.79e-10
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bHLH-PAS_NPAS3_PASD6 | cd19732 | basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing ... |
1-22 | 1.17e-08 | |||||
basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 3 (NPAS3) and similar proteins; NPAS3, also termed neuronal PAS3, or Basic-helix-loop-helix-PAS protein MOP6, or Class E basic helix-loop-helix protein 12 (bHLHe12), or member of PAS protein 6, or PAS domain-containing protein 6 (PASD6), is a bHLH-PAS brain-enriched transcription factor that is involved in central nervous system development and neurogenesis. It is a replicated genetic risk factor for psychiatric disorders. Human chromosomal rearrangements that affect NPAS3 normal expression are associated with schizophrenia and mental retardation. Pssm-ID: 381575 Cd Length: 78 Bit Score: 52.70 E-value: 1.17e-08
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PAS | smart00091 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
227-283 | 8.61e-06 | |||||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. Pssm-ID: 214512 Cd Length: 67 Bit Score: 43.93 E-value: 8.61e-06
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MSCRAMM_ClfA | NF033609 | MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
332-491 | 2.55e-04 | |||||
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif. Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.90 E-value: 2.55e-04
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MSCRAMM_ClfA | NF033609 | MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
366-560 | 4.44e-04 | |||||
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif. Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.13 E-value: 4.44e-04
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MSCRAMM_ClfA | NF033609 | MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
366-491 | 9.72e-04 | |||||
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif. Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 42.97 E-value: 9.72e-04
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sensory_box | TIGR00229 | PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain ... |
43-115 | 1.26e-03 | |||||
PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain occupies the central portion of the PAS domain but is more widely distributed. It is often tandemly repeated. Known prosthetic groups bound in the S-box domain include heme in the oxygen sensor FixL, FAD in the redox potential sensor NifL, and a 4-hydroxycinnamyl chromophore in photoactive yellow protein. Proteins containing the domain often contain other regulatory domains such as response regulator or sensor histidine kinase domains. Other S-box proteins include phytochromes and the aryl hydrocarbon receptor nuclear translocator. [Regulatory functions, Small molecule interactions] Pssm-ID: 272971 [Multi-domain] Cd Length: 124 Bit Score: 39.58 E-value: 1.26e-03
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PAS | COG2202 | PAS domain [Signal transduction mechanisms]; |
38-106 | 2.06e-03 | |||||
PAS domain [Signal transduction mechanisms]; Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 40.78 E-value: 2.06e-03
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MSCRAMM_ClfA | NF033609 | MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
366-565 | 2.11e-03 | |||||
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif. Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 41.82 E-value: 2.11e-03
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PAS | COG2202 | PAS domain [Signal transduction mechanisms]; |
230-316 | 2.72e-03 | |||||
PAS domain [Signal transduction mechanisms]; Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 40.39 E-value: 2.72e-03
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KinE | COG5809 | Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
50-309 | 5.58e-03 | |||||
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]; Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 39.96 E-value: 5.58e-03
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Name | Accession | Description | Interval | E-value | |||||
PAS_3 | pfam08447 | PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
239-326 | 1.66e-18 | |||||
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. Pssm-ID: 430001 [Multi-domain] Cd Length: 89 Bit Score: 80.85 E-value: 1.66e-18
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PAS | cd00130 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
227-309 | 1.89e-13 | |||||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction. Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 66.89 E-value: 1.89e-13
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PAS | smart00091 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
48-106 | 1.59e-11 | |||||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. Pssm-ID: 214512 Cd Length: 67 Bit Score: 60.49 E-value: 1.59e-11
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PAS | cd00130 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
54-106 | 3.67e-10 | |||||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction. Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 57.64 E-value: 3.67e-10
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PAS | pfam00989 | PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
48-106 | 7.79e-10 | |||||
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain can bind gases (O2, CO and NO), FAD, 4-hydroxycinnamic acid and NAD+ (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://0-doi-org.brum.beds.ac.uk/10.1093/femsre/fuab043). Pssm-ID: 395786 [Multi-domain] Cd Length: 113 Bit Score: 57.04 E-value: 7.79e-10
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bHLH-PAS_NPAS3_PASD6 | cd19732 | basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing ... |
1-22 | 1.17e-08 | |||||
basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 3 (NPAS3) and similar proteins; NPAS3, also termed neuronal PAS3, or Basic-helix-loop-helix-PAS protein MOP6, or Class E basic helix-loop-helix protein 12 (bHLHe12), or member of PAS protein 6, or PAS domain-containing protein 6 (PASD6), is a bHLH-PAS brain-enriched transcription factor that is involved in central nervous system development and neurogenesis. It is a replicated genetic risk factor for psychiatric disorders. Human chromosomal rearrangements that affect NPAS3 normal expression are associated with schizophrenia and mental retardation. Pssm-ID: 381575 Cd Length: 78 Bit Score: 52.70 E-value: 1.17e-08
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bHLH-PAS_NPAS1_PASD5 | cd19731 | basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing ... |
1-20 | 3.38e-07 | |||||
basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 1 (NPAS1) and similar proteins; NPAS1, also termed neuronal PAS1, or Basic-helix-loop-helix-PAS protein MOP5, or Class E basic helix-loop-helix protein 11 (bHLHe11), or member of PAS protein 5, or PAS domain-containing protein 5 (PASD5), is a bHLH-PAS transcriptional repressor expressed in the central nervous system and involved in neuronal differentiation. It is active during late embryogenesis and postnatal development. Pssm-ID: 381574 Cd Length: 74 Bit Score: 48.37 E-value: 3.38e-07
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PAS | smart00091 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
227-283 | 8.61e-06 | |||||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. Pssm-ID: 214512 Cd Length: 67 Bit Score: 43.93 E-value: 8.61e-06
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bHLH-PAS_trachealess_like | cd19733 | basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in Drosophila melanogaster protein ... |
1-24 | 1.14e-05 | |||||
basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in Drosophila melanogaster protein trachealess and similar proteins; Protein trachealess is a bHLH-PAS transcription factor that acts as an inducer of tracheal cell fates in Drosophila. It is necessary for the development of the salivary gland duct and the posterior spiracles. Pssm-ID: 381576 Cd Length: 79 Bit Score: 44.15 E-value: 1.14e-05
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MSCRAMM_ClfA | NF033609 | MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
332-491 | 2.55e-04 | |||||
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif. Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.90 E-value: 2.55e-04
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MSCRAMM_ClfA | NF033609 | MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
366-560 | 4.44e-04 | |||||
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif. Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.13 E-value: 4.44e-04
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MSCRAMM_ClfA | NF033609 | MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
366-491 | 9.72e-04 | |||||
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif. Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 42.97 E-value: 9.72e-04
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sensory_box | TIGR00229 | PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain ... |
43-115 | 1.26e-03 | |||||
PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain occupies the central portion of the PAS domain but is more widely distributed. It is often tandemly repeated. Known prosthetic groups bound in the S-box domain include heme in the oxygen sensor FixL, FAD in the redox potential sensor NifL, and a 4-hydroxycinnamyl chromophore in photoactive yellow protein. Proteins containing the domain often contain other regulatory domains such as response regulator or sensor histidine kinase domains. Other S-box proteins include phytochromes and the aryl hydrocarbon receptor nuclear translocator. [Regulatory functions, Small molecule interactions] Pssm-ID: 272971 [Multi-domain] Cd Length: 124 Bit Score: 39.58 E-value: 1.26e-03
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PAS | COG2202 | PAS domain [Signal transduction mechanisms]; |
38-106 | 2.06e-03 | |||||
PAS domain [Signal transduction mechanisms]; Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 40.78 E-value: 2.06e-03
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MSCRAMM_ClfA | NF033609 | MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
366-565 | 2.11e-03 | |||||
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif. Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 41.82 E-value: 2.11e-03
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PAS | COG2202 | PAS domain [Signal transduction mechanisms]; |
230-316 | 2.72e-03 | |||||
PAS domain [Signal transduction mechanisms]; Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 40.39 E-value: 2.72e-03
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KinE | COG5809 | Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
50-309 | 5.58e-03 | |||||
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]; Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 39.96 E-value: 5.58e-03
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Blast search parameters | ||||
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