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Conserved domains on  [gi|1907134308|ref|XP_036013224|]
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AP-4 complex subunit epsilon-1 isoform X3 [Mus musculus]

Protein Classification

AP4E_app_platf domain-containing protein( domain architecture ID 13560692)

AP4E_app_platf domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Adaptin_N super family cl37648
Adaptin N terminal region; This family consists of the N terminal region of various alpha, ...
2-517 2.97e-79

Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles.


The actual alignment was detected with superfamily member pfam01602:

Pssm-ID: 396262 [Multi-domain]  Cd Length: 523  Bit Score: 268.72  E-value: 2.97e-79
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308    2 KECMVRLIYCEMLGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVV 81
Cdd:pfam01602   24 KNAVKKLLYLIMLGEDISFLFFEVVKLVASKDFTLKRLGYLYLMLLAEESPDLAILVTNSIQKDLQSPNQLIRGLALRTL 103
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308   82 SQIFPREMIPAVLPLIEDKLQHSKEIIRRKAVLALYKFYLIAPNQVQHIHTKFRKALCDRDVGVMAASLHIYLRMIKENA 161
Cdd:pfam01602  104 SCIRVPELARDLAPDIKKLLVDRSPYVRKKAALAILKLYRKSPDLVRDFVPELKELLSDKDPGVQSAAVALLYEICKNDR 183
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  162 SgYKDLTESFVTILKQVVGgklpvefsyhsVPAPWLQIQLLRILGLLGKDDERTSELMYDVLDESLRraelnhNVTYAIL 241
Cdd:pfam01602  184 L-YLKLLPLLFRRLCNLLG-----------VLNPWLQVKILRLLTRLAPLDPLLPKELLEDLLNLLQ------NSNNAVL 245
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  242 FECVHTIYSIYPKSELLEKAAKCIGKFVLSPKINLKYLGLKALTYVIQQDPSlALQHQITIIECLDHPDPI-IKRETLEL 320
Cdd:pfam01602  246 YETANTIVHLAPAPELIVLAVNALGRLLSSPDENLRYVALRNLNKIVMKEPK-AVQHLDLIIFCLKTDDDIsIRLRALDL 324
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  321 LYRITNAQNVVVIVQKMLEYLHQSKEEHIIISLVGRIAELAEKYAPDNVWFIQTMNAVFSVGGDVMHPDILSNFLRLLae 400
Cdd:pfam01602  325 LYALVNESNVKEIVKELLKYVHEIADPDFKIELVRAIGRLAEKFPTDAEWYLDVLLDLLSLAGSYVVDEIVEVIRDII-- 402
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  401 gfddeTEDQQLRLYAVQS-YLTLLDMENtfypQRFLQVMSWVLGEYSYLL-DKESPEEVITRLYKLLMSDSIssETKAWL 478
Cdd:pfam01602  403 -----QNVPELREYILEHlCELLEDIES----PEALAAALWILGEYGELIpNGSSPPDLLRSILEVFVLESA--KVRAAA 471
                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 1907134308  479 FAAVTKLTPQAHSSPLVEKLIQEFTvslnTCLRQHAFEL 517
Cdd:pfam01602  472 LTALAKLGLTSPEETTQNLIIQLLL----TLATQDSLDL 506
AP4E_app_platf pfam14807
Adaptin AP4 complex epsilon appendage platform; This domain is found at the C terminal of ...
943-1043 1.81e-38

Adaptin AP4 complex epsilon appendage platform; This domain is found at the C terminal of clathrin-adaptor epsilon subunit, and at the C-terminus of the appendage on the platform domain.


:

Pssm-ID: 464326  Cd Length: 100  Bit Score: 138.55  E-value: 1.81e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  943 PLKISTEDFGKLWLSFANDVKQTIKisEPGVALTSVLTELQQNLRLRVIDVIGNEGLLACKLLPST-PCVLHCRVHADAV 1021
Cdd:pfam14807    1 PLTISTEEFGQLWLSFSNERKQNLK--SSQVSTLSDLNLLLQKLHLHVVEVIGNEGIVACQLLNSSnPCLLHVRVNAGVL 78
                           90       100
                   ....*....|....*....|..
gi 1907134308 1022 ALWFRSSSSVLSDYLSCHCQKV 1043
Cdd:pfam14807   79 DVWVRSNDKPLADCVLYHCQRA 100
 
Name Accession Description Interval E-value
Adaptin_N pfam01602
Adaptin N terminal region; This family consists of the N terminal region of various alpha, ...
2-517 2.97e-79

Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles.


Pssm-ID: 396262 [Multi-domain]  Cd Length: 523  Bit Score: 268.72  E-value: 2.97e-79
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308    2 KECMVRLIYCEMLGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVV 81
Cdd:pfam01602   24 KNAVKKLLYLIMLGEDISFLFFEVVKLVASKDFTLKRLGYLYLMLLAEESPDLAILVTNSIQKDLQSPNQLIRGLALRTL 103
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308   82 SQIFPREMIPAVLPLIEDKLQHSKEIIRRKAVLALYKFYLIAPNQVQHIHTKFRKALCDRDVGVMAASLHIYLRMIKENA 161
Cdd:pfam01602  104 SCIRVPELARDLAPDIKKLLVDRSPYVRKKAALAILKLYRKSPDLVRDFVPELKELLSDKDPGVQSAAVALLYEICKNDR 183
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  162 SgYKDLTESFVTILKQVVGgklpvefsyhsVPAPWLQIQLLRILGLLGKDDERTSELMYDVLDESLRraelnhNVTYAIL 241
Cdd:pfam01602  184 L-YLKLLPLLFRRLCNLLG-----------VLNPWLQVKILRLLTRLAPLDPLLPKELLEDLLNLLQ------NSNNAVL 245
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  242 FECVHTIYSIYPKSELLEKAAKCIGKFVLSPKINLKYLGLKALTYVIQQDPSlALQHQITIIECLDHPDPI-IKRETLEL 320
Cdd:pfam01602  246 YETANTIVHLAPAPELIVLAVNALGRLLSSPDENLRYVALRNLNKIVMKEPK-AVQHLDLIIFCLKTDDDIsIRLRALDL 324
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  321 LYRITNAQNVVVIVQKMLEYLHQSKEEHIIISLVGRIAELAEKYAPDNVWFIQTMNAVFSVGGDVMHPDILSNFLRLLae 400
Cdd:pfam01602  325 LYALVNESNVKEIVKELLKYVHEIADPDFKIELVRAIGRLAEKFPTDAEWYLDVLLDLLSLAGSYVVDEIVEVIRDII-- 402
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  401 gfddeTEDQQLRLYAVQS-YLTLLDMENtfypQRFLQVMSWVLGEYSYLL-DKESPEEVITRLYKLLMSDSIssETKAWL 478
Cdd:pfam01602  403 -----QNVPELREYILEHlCELLEDIES----PEALAAALWILGEYGELIpNGSSPPDLLRSILEVFVLESA--KVRAAA 471
                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 1907134308  479 FAAVTKLTPQAHSSPLVEKLIQEFTvslnTCLRQHAFEL 517
Cdd:pfam01602  472 LTALAKLGLTSPEETTQNLIIQLLL----TLATQDSLDL 506
AP4E_app_platf pfam14807
Adaptin AP4 complex epsilon appendage platform; This domain is found at the C terminal of ...
943-1043 1.81e-38

Adaptin AP4 complex epsilon appendage platform; This domain is found at the C terminal of clathrin-adaptor epsilon subunit, and at the C-terminus of the appendage on the platform domain.


Pssm-ID: 464326  Cd Length: 100  Bit Score: 138.55  E-value: 1.81e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  943 PLKISTEDFGKLWLSFANDVKQTIKisEPGVALTSVLTELQQNLRLRVIDVIGNEGLLACKLLPST-PCVLHCRVHADAV 1021
Cdd:pfam14807    1 PLTISTEEFGQLWLSFSNERKQNLK--SSQVSTLSDLNLLLQKLHLHVVEVIGNEGIVACQLLNSSnPCLLHVRVNAGVL 78
                           90       100
                   ....*....|....*....|..
gi 1907134308 1022 ALWFRSSSSVLSDYLSCHCQKV 1043
Cdd:pfam14807   79 DVWVRSNDKPLADCVLYHCQRA 100
COG5096 COG5096
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ...
2-485 6.29e-14

Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 227427 [Multi-domain]  Cd Length: 757  Bit Score: 76.31  E-value: 6.29e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308    2 KECMVRLIYCEMLGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVV 81
Cdd:COG5096     37 IDAMKKIIAQMSLGEDMSSLFPDVIKNVATRDVELKRLLYLYLERYAKLKPELALLAVNTIQKDLQDPNEEIRGFALRTL 116
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308   82 SQIFPREMIPAVLPLIEDKLQHSKEIIRRKAVLALYKFYLIAPNQVQH----IHTKFrkALCDRDVGVMAASLHIYLRMI 157
Cdd:COG5096    117 SLLRVKELLGNIIDPIKKLLTDPHAYVRKTAALAVAKLYRLDKDLYHElgliDILKE--LVADSDPIVIANALASLAEID 194
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  158 KENASGYKdltESFVTILKQvvggklpVEFSYHSVPAPWLQIQLLRILGLLGKDDERTSELMydvldESLRRAELNHNVT 237
Cdd:COG5096    195 PELAHGYS---LEVILRIPQ-------LDLLSLSVSTEWLLLIILEVLTERVPTTPDSAEDF-----EERLSPPLQHNNA 259
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  238 YAILFEcVHTIYSIYPKSELLEKAAKCIGKFVL---SPKINLKYLGLKALTYVIQQdPSLALQHQITIIECLDHPDPIIK 314
Cdd:COG5096    260 EVLLIA-VKVILRLLVFLPSNNLFLISSPPLVTllaKPESLIQYVLRRNIQIDLEV-CSKLLDKVKKLFLIEYNDDIYIK 337
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  315 RETLELLYRITNAQNVVVIVQKMLEYLH-------------------QSKEEHIIISLvgrIAELAEKY--APDNVWFIQ 373
Cdd:COG5096    338 LEKLDQLTRLADDQNLSQILLELIYYIAenhidaemvseaikalgdlASKAESSVNDC---ISELLELLegVWIRGSYIV 414
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  374 TMNAVFSVggdVMHPDILSNFLRLLAegfdDETEDQQLR-LYAVQSYLTLLDMentfyPQRFLQVMS-----WVLGEYSY 447
Cdd:COG5096    415 QEVRIVDC---ISVIRISVLVLRILP----NEYPKILLRgLYALEETLELQSR-----EPRAKSVTDkylgaWLLGEFSD 482
                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 1907134308  448 LLDKESPEevITRLYKLLMSDSiSSETKAWLFAAVTKL 485
Cdd:COG5096    483 IIPRLEPE--LLRIAISNFVDE-TLEVQYTILMSSVKL 517
 
Name Accession Description Interval E-value
Adaptin_N pfam01602
Adaptin N terminal region; This family consists of the N terminal region of various alpha, ...
2-517 2.97e-79

Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles.


Pssm-ID: 396262 [Multi-domain]  Cd Length: 523  Bit Score: 268.72  E-value: 2.97e-79
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308    2 KECMVRLIYCEMLGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVV 81
Cdd:pfam01602   24 KNAVKKLLYLIMLGEDISFLFFEVVKLVASKDFTLKRLGYLYLMLLAEESPDLAILVTNSIQKDLQSPNQLIRGLALRTL 103
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308   82 SQIFPREMIPAVLPLIEDKLQHSKEIIRRKAVLALYKFYLIAPNQVQHIHTKFRKALCDRDVGVMAASLHIYLRMIKENA 161
Cdd:pfam01602  104 SCIRVPELARDLAPDIKKLLVDRSPYVRKKAALAILKLYRKSPDLVRDFVPELKELLSDKDPGVQSAAVALLYEICKNDR 183
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  162 SgYKDLTESFVTILKQVVGgklpvefsyhsVPAPWLQIQLLRILGLLGKDDERTSELMYDVLDESLRraelnhNVTYAIL 241
Cdd:pfam01602  184 L-YLKLLPLLFRRLCNLLG-----------VLNPWLQVKILRLLTRLAPLDPLLPKELLEDLLNLLQ------NSNNAVL 245
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  242 FECVHTIYSIYPKSELLEKAAKCIGKFVLSPKINLKYLGLKALTYVIQQDPSlALQHQITIIECLDHPDPI-IKRETLEL 320
Cdd:pfam01602  246 YETANTIVHLAPAPELIVLAVNALGRLLSSPDENLRYVALRNLNKIVMKEPK-AVQHLDLIIFCLKTDDDIsIRLRALDL 324
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  321 LYRITNAQNVVVIVQKMLEYLHQSKEEHIIISLVGRIAELAEKYAPDNVWFIQTMNAVFSVGGDVMHPDILSNFLRLLae 400
Cdd:pfam01602  325 LYALVNESNVKEIVKELLKYVHEIADPDFKIELVRAIGRLAEKFPTDAEWYLDVLLDLLSLAGSYVVDEIVEVIRDII-- 402
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  401 gfddeTEDQQLRLYAVQS-YLTLLDMENtfypQRFLQVMSWVLGEYSYLL-DKESPEEVITRLYKLLMSDSIssETKAWL 478
Cdd:pfam01602  403 -----QNVPELREYILEHlCELLEDIES----PEALAAALWILGEYGELIpNGSSPPDLLRSILEVFVLESA--KVRAAA 471
                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 1907134308  479 FAAVTKLTPQAHSSPLVEKLIQEFTvslnTCLRQHAFEL 517
Cdd:pfam01602  472 LTALAKLGLTSPEETTQNLIIQLLL----TLATQDSLDL 506
AP4E_app_platf pfam14807
Adaptin AP4 complex epsilon appendage platform; This domain is found at the C terminal of ...
943-1043 1.81e-38

Adaptin AP4 complex epsilon appendage platform; This domain is found at the C terminal of clathrin-adaptor epsilon subunit, and at the C-terminus of the appendage on the platform domain.


Pssm-ID: 464326  Cd Length: 100  Bit Score: 138.55  E-value: 1.81e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  943 PLKISTEDFGKLWLSFANDVKQTIKisEPGVALTSVLTELQQNLRLRVIDVIGNEGLLACKLLPST-PCVLHCRVHADAV 1021
Cdd:pfam14807    1 PLTISTEEFGQLWLSFSNERKQNLK--SSQVSTLSDLNLLLQKLHLHVVEVIGNEGIVACQLLNSSnPCLLHVRVNAGVL 78
                           90       100
                   ....*....|....*....|..
gi 1907134308 1022 ALWFRSSSSVLSDYLSCHCQKV 1043
Cdd:pfam14807   79 DVWVRSNDKPLADCVLYHCQRA 100
COG5096 COG5096
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ...
2-485 6.29e-14

Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 227427 [Multi-domain]  Cd Length: 757  Bit Score: 76.31  E-value: 6.29e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308    2 KECMVRLIYCEMLGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVV 81
Cdd:COG5096     37 IDAMKKIIAQMSLGEDMSSLFPDVIKNVATRDVELKRLLYLYLERYAKLKPELALLAVNTIQKDLQDPNEEIRGFALRTL 116
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308   82 SQIFPREMIPAVLPLIEDKLQHSKEIIRRKAVLALYKFYLIAPNQVQH----IHTKFrkALCDRDVGVMAASLHIYLRMI 157
Cdd:COG5096    117 SLLRVKELLGNIIDPIKKLLTDPHAYVRKTAALAVAKLYRLDKDLYHElgliDILKE--LVADSDPIVIANALASLAEID 194
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  158 KENASGYKdltESFVTILKQvvggklpVEFSYHSVPAPWLQIQLLRILGLLGKDDERTSELMydvldESLRRAELNHNVT 237
Cdd:COG5096    195 PELAHGYS---LEVILRIPQ-------LDLLSLSVSTEWLLLIILEVLTERVPTTPDSAEDF-----EERLSPPLQHNNA 259
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  238 YAILFEcVHTIYSIYPKSELLEKAAKCIGKFVL---SPKINLKYLGLKALTYVIQQdPSLALQHQITIIECLDHPDPIIK 314
Cdd:COG5096    260 EVLLIA-VKVILRLLVFLPSNNLFLISSPPLVTllaKPESLIQYVLRRNIQIDLEV-CSKLLDKVKKLFLIEYNDDIYIK 337
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  315 RETLELLYRITNAQNVVVIVQKMLEYLH-------------------QSKEEHIIISLvgrIAELAEKY--APDNVWFIQ 373
Cdd:COG5096    338 LEKLDQLTRLADDQNLSQILLELIYYIAenhidaemvseaikalgdlASKAESSVNDC---ISELLELLegVWIRGSYIV 414
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907134308  374 TMNAVFSVggdVMHPDILSNFLRLLAegfdDETEDQQLR-LYAVQSYLTLLDMentfyPQRFLQVMS-----WVLGEYSY 447
Cdd:COG5096    415 QEVRIVDC---ISVIRISVLVLRILP----NEYPKILLRgLYALEETLELQSR-----EPRAKSVTDkylgaWLLGEFSD 482
                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 1907134308  448 LLDKESPEevITRLYKLLMSDSiSSETKAWLFAAVTKL 485
Cdd:COG5096    483 IIPRLEPE--LLRIAISNFVDE-TLEVQYTILMSSVKL 517
Coatomer_b_Cpla pfam14806
Coatomer beta subunit appendage platform; This family is found at the C-terminus of the ...
937-1004 5.21e-04

Coatomer beta subunit appendage platform; This family is found at the C-terminus of the coatamer beta subunit proteins (Beta-coat proteins). It is a platform domain on the appendage that carries a highly conserved tryptophan.


Pssm-ID: 434227  Cd Length: 128  Bit Score: 41.02  E-value: 5.21e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907134308  937 LLDFIRPLKISTEDFGKLWLSFANDVKQTIKISEPGvaLTSVLTELQQNLRLRVI----DVIGNEGLLACKL 1004
Cdd:pfam14806   14 IMDYIKPATCDDEEFREMWAEFEWENKITVNTNITD--LREYLDHLMKKTNMNCLtpeeALSGECGFLSANL 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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