|
Name |
Accession |
Description |
Interval |
E-value |
| ATG11 |
pfam10377 |
Autophagy-related protein 11; The function of this family is conflicting. In the fission yeast, ... |
1308-1402 |
2.71e-26 |
|
Autophagy-related protein 11; The function of this family is conflicting. In the fission yeast, Schizosaccharomyces pombe, this protein has been shown to interact with the telomere cap complex and it is also required for dimerization and kinase activation of Atg1. However, in budding yeast, Saccharomyces cerevisiae, this protein is called ATG11 and is shown to be involved in autophagy.
Pssm-ID: 463063 Cd Length: 130 Bit Score: 105.38 E-value: 2.71e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1308 EKIAIRDFQVGDLVLIILDERHDN-----YVLFTVSPTLYFLHSESLPALdlkpgegasgaSRRPWVLGKVMEKEYCQAK 1382
Cdd:pfam10377 38 EKITLKNFKVGDLALFLPTRRHNDlstppWAAFNVGAPHYFLKADSLLAL-----------KSREWFVGRITSIEERVVD 106
|
90 100
....*....|....*....|...
gi 1907067116 1383 ---KAQNRFKVPLGTKFYRVKAV 1402
Cdd:pfam10377 107 lsdKDSNPFKLSKGTVWYLVTAE 129
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
629-1119 |
1.86e-12 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 71.98 E-value: 1.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 629 KEQCDLANYLKCTAVEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNK----ILKLKENLVSLE 704
Cdd:TIGR04523 166 KQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQlkdnIEKKQQEINEKT 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 705 EALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKqsreMALEDLKKLHDEKIESLRAEFQCLEQN 784
Cdd:TIGR04523 246 TEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK----SEISDLNNQKEQDWNKELKSELKNQEK 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 785 HLKELEDTLhirhtQEFEKVMTDHNMSLEKLKKE------NQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKL 858
Cdd:TIGR04523 322 KLEEIQNQI-----SQNNKIISQLNEQISQLKKEltnsesENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDL 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 859 EVELALKEAETDEIkilleESRTQQKEMLKSLLEQETENLRTEISKLNQKIHD-NNESYQVGLS--ELRALMTIEKDQCI 935
Cdd:TIGR04523 397 ESKIQNQEKLNQQK-----DEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDlTNQDSVKELIikNLDNTRESLETQLK 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 936 SELISRHEEESN--ILKAELDNVTSLHRQAYEIEKKLKEQIVELqTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKD 1013
Cdd:TIGR04523 472 VLSRSINKIKQNleQKQKELKSKEKELKKLNEEKKELEEKVKDL-TKKISSLKEKIEKLESEKKEKESKISDLEDELNKD 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1014 KERLVKNH-EQDKEHLIQELnfEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEK 1092
Cdd:TIGR04523 551 DFELKKENlEKEIDEKNKEI--EELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEK 628
|
490 500 510
....*....|....*....|....*....|
gi 1907067116 1093 LQEEKAKF---LEQLEEQEKRKNEEMQNVR 1119
Cdd:TIGR04523 629 LSSIIKNIkskKNKLKQEVKQIKETIKEIR 658
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
597-1175 |
5.88e-12 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 70.92 E-value: 5.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 597 VQLEKCRAAAQDSHSSIQTIkddlcHFRTF------VQKEQCDLANYLKCTAVEIRNIIEKVKCS----LEITLKEkHQQ 666
Cdd:pfam15921 194 VDFEEASGKKIYEHDSMSTM-----HFRSLgsaiskILRELDTEISYLKGRIFPVEDQLEALKSEsqnkIELLLQQ-HQD 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 667 ELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEF--------TSIKHEKDAIVCVQQEKDQKLLEM 738
Cdd:pfam15921 268 RIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYmrqlsdleSTVSQLRSELREAKRMYEDKIEEL 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 739 EKIMHTQHCEIKELKQSREMALEDLKKLhDEKIESLRAEFqcleqnHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKE 818
Cdd:pfam15921 348 EKQLVLANSELTEARTERDQFSQESGNL-DDQLQKLLADL------HKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 819 ------NQQRIDQMLESHASTIQ-EKEQQLQELKLKVSDL---SDMRCKLEVELALKEAETDEI---KILLEESRTQQKE 885
Cdd:pfam15921 421 lddrnmEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLekvSSLTAQLESTKEMLRKVVEELtakKMTLESSERTVSD 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 886 MLKSLLEQE--TENLRTEISKLNQKI--------HDNNE-----SYQVGLSELRALMTiEKDQCISELISRHEEESNILK 950
Cdd:pfam15921 501 LTASLQEKEraIEATNAEITKLRSRVdlklqelqHLKNEgdhlrNVQTECEALKLQMA-EKDKVIEILRQQIENMTQLVG 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 951 AELDNVTSLHRQAYEIEKKLKEQIVELQtrlnsELSALEKQKDEKITQQEEKYEAL------IQNLEKDKERLVKNHEQD 1024
Cdd:pfam15921 580 QHGRTAGAMQVEKAQLEKEINDRRLELQ-----EFKILKDKKDAKIRELEARVSDLelekvkLVNAGSERLRAVKDIKQE 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1025 KEHLIQELNFEKNKaVQTALDEFKV----------ERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQ 1094
Cdd:pfam15921 655 RDQLLNEVKTSRNE-LNSLSEDYEVlkrnfrnkseEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQ 733
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1095 EE-------------KAKFLEQ-----------LEEQEKRKNEEMQNVRTSLiAEQQTNFNTVLTREKMRKENIINDLSD 1150
Cdd:pfam15921 734 KQitakrgqidalqsKIQFLEEamtnankekhfLKEEKNKLSQELSTVATEK-NKMAGELEVLRSQERRLKEKVANMEVA 812
|
650 660
....*....|....*....|....*
gi 1907067116 1151 KLKSTMQQQERdKDLIESLSEDRAR 1175
Cdd:pfam15921 813 LDKASLQFAEC-QDIIQRQEQESVR 836
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
834-1120 |
5.93e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.86 E-value: 5.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 834 IQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAEtdeikilLEESRTQQKEMLKSLLEQETE--NLRTEISKLNQKI-- 909
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEK-------LEELRLEVSELEEEIEELQKElyALANEISRLEQQKqi 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 910 --------HDNNESYQVGLSELRAlmtieKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRL 981
Cdd:TIGR02168 307 lrerlanlERQLEELEAQLEELES-----KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 982 NSELSALEKqkdekITQQEEKYEALIQNLEKDKERLVKNHEQdkehLIQELNFEKNKAVQTALDEFKVERELVEKELLEK 1061
Cdd:TIGR02168 382 ETLRSKVAQ-----LELQIASLNNEIERLEARLERLEDRRER----LQQEIEELLKKLEEAELKELQAELEELEEELEEL 452
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1907067116 1062 VKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRT 1120
Cdd:TIGR02168 453 QEELERLEEALEELREELEEAEQALDAAERELAQLQAR-LDSLERLQENLEGFSEGVKA 510
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
678-1172 |
2.97e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 68.12 E-value: 2.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 678 KLDALVKDSEENVNKILKLKENL----VSLEEALQNKDNEFTSIKHE---KDAIVCVQQEKDQKLLEMEKimhtqhcEIK 750
Cdd:TIGR04523 149 KKEKELEKLNNKYNDLKKQKEELenelNLLEKEKLNIQKNIDKIKNKllkLELLLSNLKKKIQKNKSLES-------QIS 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 751 ELKQSREmALEDLKKLHDEKIESLRAEFQCLEQNhLKELEDtlhirhtqefekvmtdhnmSLEKLKKENQQRIDQmLESH 830
Cdd:TIGR04523 222 ELKKQNN-QLKDNIEKKQQEINEKTTEISNTQTQ-LNQLKD-------------------EQNKIKKQLSEKQKE-LEQN 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 831 ASTIQEKEQQLQELKLKVSDLSdmrcklevelalKEAETDEIKILLEESRTQQKEmlKSLLEQETENLRTEISKLNQKIH 910
Cdd:TIGR04523 280 NKKIKELEKQLNQLKSEISDLN------------NQKEQDWNKELKSELKNQEKK--LEEIQNQISQNNKIISQLNEQIS 345
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 911 D----------NNESYQVGLSE-LRALMTIEKD-QCISELISRHEEESNILKAELDNVTslhrqayEIEKKLKEQIVELQ 978
Cdd:TIGR04523 346 QlkkeltnsesENSEKQRELEEkQNEIEKLKKEnQSYKQEIKNLESQINDLESKIQNQE-------KLNQQKDEQIKKLQ 418
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 979 TRLNSELSALEKQKDEKITQQEEkyealIQNLEKD---KERLVKNHEQDKEHL---IQELNFEKNKaVQTALDEFKVERE 1052
Cdd:TIGR04523 419 QEKELLEKEIERLKETIIKNNSE-----IKDLTNQdsvKELIIKNLDNTRESLetqLKVLSRSINK-IKQNLEQKQKELK 492
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1053 LVEKELL---EKVKHLENQIAKTpafesarEDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIA----- 1124
Cdd:TIGR04523 493 SKEKELKklnEEKKELEEKVKDL-------TKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEkeide 565
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 1907067116 1125 -----EQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSED 1172
Cdd:TIGR04523 566 knkeiEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
827-1110 |
3.11e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.42 E-value: 3.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 827 LESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSL--LEQETENLRTEISK 904
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEyeLLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 905 LNQKIHDNNESYQVGLSELRALmtIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSE 984
Cdd:COG1196 307 LEERRRELEERLEELEEELAEL--EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 985 LSAL--EKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELnfeknkavqTALDEFKVERELVEKELLEKV 1062
Cdd:COG1196 385 AEELleALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE---------EEEEEEEEALEEAAEEEAELE 455
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1907067116 1063 KHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKR 1110
Cdd:COG1196 456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
649-1120 |
4.09e-11 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 67.82 E-value: 4.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 649 IEKVKCSLE--ITLKEKHQQELQ-------SLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKH 719
Cdd:pfam05483 298 LEDIKMSLQrsMSTQKALEEDLQiatkticQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNED 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 720 EKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQsremALEDLKKLHDEK--IESLRAEFQCLEQN------------H 785
Cdd:pfam05483 378 QLKIITMELQKKSSELEEMTKFKNNKEVELEELKK----ILAEDEKLLDEKkqFEKIAEELKGKEQElifllqarekeiH 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 786 LKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQ---RIDQMLESHASTIQEKEQQLQELKLKVSDLSDmrCKLEVEL 862
Cdd:pfam05483 454 DLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEltaHCDKLLLENKELTQEASDMTLELKKHQEDIIN--CKKQEER 531
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 863 ALKEAETdeikilLEESRTQQKEMLKSLLEqETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCiselisrh 942
Cdd:pfam05483 532 MLKQIEN------LEEKEMNLRDELESVRE-EFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKC-------- 596
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 943 eeesNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEkITQQEEKYEALIQNLEKDkerlVKNHE 1022
Cdd:pfam05483 597 ----NNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELE-LASAKQKFEEIIDNYQKE----IEDKK 667
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1023 QDKEHLIQELnfekNKAVQTALDEFKVERELVEK---------ELLEKVKH-----LENQIAKTPAFESAREDSSSLVAE 1088
Cdd:pfam05483 668 ISEEKLLEEV----EKAKAIADEAVKLQKEIDKRcqhkiaemvALMEKHKHqydkiIEERDSELGLYKNKEQEQSSAKAA 743
|
490 500 510
....*....|....*....|....*....|....*....
gi 1907067116 1089 LQEKLQEEKAKFLE-------QLEEQEKRKNEEMQNVRT 1120
Cdd:pfam05483 744 LEIELSNIKAELLSlkkqleiEKEEKEKLKMEAKENTAI 782
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
857-1171 |
8.23e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.00 E-value: 8.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 857 KLEVELALKEAETDEIKILLEESRTQQKEmlkslLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALmtiekdqciS 936
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAELRKELEE-----LEEELEQLRKELEELSRQISALRKDLARLEAEVEQL---------E 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 937 ELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKdEKITQQEEKYEALIQNLEKDKER 1016
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRER 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1017 LvKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEK-----ELLEKVKHLENQIAKTP-AFESAREDSSSLVAELQ 1090
Cdd:TIGR02168 826 L-ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELeelieELESELEALLNERASLEeALALLRSELEELSEELR 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1091 EKlqEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLS 1170
Cdd:TIGR02168 905 EL--ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
|
.
gi 1907067116 1171 E 1171
Cdd:TIGR02168 983 E 983
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
835-1160 |
1.47e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 66.11 E-value: 1.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 835 QEKEQQLQELKLKVSdLSDMRcKLEVELALKEAETDEIKILLEESRTQQKEmlkslLEQETENLRTEISKLNQKIHDNNE 914
Cdd:COG1196 216 RELKEELKELEAELL-LLKLR-ELEAELEELEAELEELEAELEELEAELAE-----LEAELEELRLELEELELELEEAQA 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 915 SYQVGLSElralmtiekdqciselISRHEEESNILKAELDNvtslhrqayeiekkLKEQIVELQTRLNSELSALEKQKDE 994
Cdd:COG1196 289 EEYELLAE----------------LARLEQDIARLEERRRE--------------LEERLEELEEELAELEEELEELEEE 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 995 KITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPA 1074
Cdd:COG1196 339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1075 FESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKS 1154
Cdd:COG1196 419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
|
....*.
gi 1907067116 1155 TMQQQE 1160
Cdd:COG1196 499 AEADYE 504
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
750-1113 |
2.30e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.47 E-value: 2.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 750 KELKQSREMAlEDLKKLHDEKiESLRAEFQCLEqNHLKELEDTLHiRHTQEFEKVMTDHNMSLEKLKKENQQridqmLES 829
Cdd:TIGR02169 671 SEPAELQRLR-ERLEGLKREL-SSLQSELRRIE-NRLDELSQELS-DASRKIGEIEKEIEQLEQEEEKLKER-----LEE 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 830 HASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKI 909
Cdd:TIGR02169 742 LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKL 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 910 ---HDNNESYQVGLSELRALMTIEKDQCISelISRHEEESNILKAELDNVTSLHRQA-YEIEKKLKEqIVELQTRLNSEL 985
Cdd:TIGR02169 822 nrlTLEKEYLEKEIQELQEQRIDLKEQIKS--IEKEIENLNGKKEELEEELEELEAAlRDLESRLGD-LKKERDELEAQL 898
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 986 SALEKqkdeKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKEL--LEKVK 1063
Cdd:TIGR02169 899 RELER----KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIraLEPVN 974
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1064 HLENQiaktpAFESAREDSSSLVaELQEKLQEEKAKFLEQLEEQEKRKNE 1113
Cdd:TIGR02169 975 MLAIQ-----EYEEVLKRLDELK-EKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
661-1161 |
2.69e-10 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 65.45 E-value: 2.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 661 KEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLvSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEK 740
Cdd:TIGR00606 499 LKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQME-MLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED 577
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 741 IMHTQHCEIKELKQSREMALEDLKKLHDEKiESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKEN- 819
Cdd:TIGR00606 578 WLHSKSKEINQTRDRLAKLNKELASLEQNK-NHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRa 656
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 820 ---------QQRIDQMLESHAS----------TIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEesr 880
Cdd:TIGR00606 657 mlagatavySQFITQLTDENQSccpvcqrvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAP--- 733
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 881 TQQKEMlkSLLEQETENLRTEISKLNQKIHdnnesyqvglselRALMTIEKDQCISELISRHEEESNILKAELDNVTSLH 960
Cdd:TIGR00606 734 GRQSII--DLKEKEIPELRNKLQKVNRDIQ-------------RLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQ 798
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 961 RQAYEIEKKLKEQIVELQTrlnSELSALEKQKDEKITQQEEKYEALIQNLEKDKeRLVKNHEQDKEHLIQELNFEKNKAV 1040
Cdd:TIGR00606 799 MELKDVERKIAQQAAKLQG---SDLDRTVQQVNQEKQEKQHELDTVVSKIELNR-KLIQDQQEQIQHLKSKTNELKSEKL 874
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1041 QtaLDEFKVERELVEKELLEKVKHLENQIAktpAFESAREDSSSLvAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRT 1120
Cdd:TIGR00606 875 Q--IGTNLQRRQQFEEQLVELSTEVQSLIR---EIKDAKEQDSPL-ETFLEKDQQEKEELISSKETSNKKAQDKVNDIKE 948
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 1907067116 1121 SL---IAEQQTNFNTV---LTREKMRKENIINDLSDKLKSTMQQQER 1161
Cdd:TIGR00606 949 KVkniHGYMKDIENKIqdgKDDYLKQKETELNTVNAQLEECEKHQEK 995
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
682-1190 |
2.80e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 65.09 E-value: 2.80e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 682 LVKDSEENVNKILKLKENLvslEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHT--QHCEIKELKQSREMA 759
Cdd:PRK03918 173 EIKRRIERLEKFIKRTENI---EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEleELKEEIEELEKELES 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 760 LEDLKKLHDEKIESLRAEFQCLEQnHLKELEDTlhIRHTQEFEKVMTDHnMSLEKLK---KENQQRIDQMLESHASTIQE 836
Cdd:PRK03918 250 LEGSKRKLEEKIRELEERIEELKK-EIEELEEK--VKELKELKEKAEEY-IKLSEFYeeyLDELREIEKRLSRLEEEING 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 837 KEQQLQELKLKVSDLSDMRcKLEVELALKEAETDEIKILLEESRTQQKEMLK-----------------SLLEQETENLR 899
Cdd:PRK03918 326 IEERIKELEEKEERLEELK-KKLKELEKRLEELEERHELYEEAKAKKEELERlkkrltgltpeklekelEELEKAKEEIE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 900 TEISKLNQKIhdnNESYQVGLSELRALMTIEKDQ-----CISELISRHEEE-SNILKAELDNVTSLHRQAYEIEKKLKEQ 973
Cdd:PRK03918 405 EEISKITARI---GELKKEIKELKKAIEELKKAKgkcpvCGRELTEEHRKElLEEYTAELKRIEKELKEIEEKERKLRKE 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 974 IVELQTRLN--SELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQ----DKEHLIQELNFEKNKAVQTALDEF 1047
Cdd:PRK03918 482 LRELEKVLKkeSELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKliklKGEIKSLKKELEKLEELKKKLAEL 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1048 KVERELVEKELLEKVKHLENQiaktpAFESAREDSSSLvAELQ------------EKLQEEKAKFLEQLEEQEKRKNEEM 1115
Cdd:PRK03918 562 EKKLDELEEELAELLKELEEL-----GFESVEELEERL-KELEpfyneylelkdaEKELEREEKELKKLEEELDKAFEEL 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1116 QNVRTSL------IAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSK 1189
Cdd:PRK03918 636 AETEKRLeelrkeLEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEK 715
|
.
gi 1907067116 1190 L 1190
Cdd:PRK03918 716 L 716
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
657-1174 |
3.49e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.96 E-value: 3.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 657 EITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLL 736
Cdd:COG1196 261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 737 EMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQcLEQNHLKELEDTLHIRHTQEfekvmtdhnmSLEKLK 816
Cdd:COG1196 341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE-LAEELLEALRAAAELAAQLE----------ELEEAE 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 817 KENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETE 896
Cdd:COG1196 410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 897 NLRtEISKLNQKIHDNNESYQVGLSELRALMTiEKDQCISELISRHEEESNILKAELDNVtsLHRQAYEIEKKLKEQIVE 976
Cdd:COG1196 490 AAR-LLLLLEAEADYEGFLEGVKAALLLAGLR-GLAGAVAVLIGVEAAYEAALEAALAAA--LQNIVVEDDEVAAAAIEY 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 977 LQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEK 1056
Cdd:COG1196 566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1057 ELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTR 1136
Cdd:COG1196 646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725
|
490 500 510
....*....|....*....|....*....|....*...
gi 1907067116 1137 EKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRA 1174
Cdd:COG1196 726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
657-1174 |
5.04e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 64.31 E-value: 5.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 657 EITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIvcvqQEKDQKLL 736
Cdd:PRK03918 173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI----EELEKELE 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 737 EMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRhTQEFEKVMTDhnmsLEKLK 816
Cdd:PRK03918 249 SLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDE-LREIEKRLSR----LEEEI 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 817 KENQQRIDQmLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEA-----------ETDEIKILLEESRTQQKE 885
Cdd:PRK03918 324 NGIEERIKE-LEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEElerlkkrltglTPEKLEKELEELEKAKEE 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 886 mlkslLEQETENLRTEISKLNQKIHDNNEsyqvglselrALMTIEKDQ-----CISELISRHEEE-SNILKAELDNVTSL 959
Cdd:PRK03918 403 -----IEEEISKITARIGELKKEIKELKK----------AIEELKKAKgkcpvCGRELTEEHRKElLEEYTAELKRIEKE 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 960 HRQAYEIEKKLKEQIVELQTRLN--SELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQ----DKEHLIQELN 1033
Cdd:PRK03918 468 LKEIEEKERKLRKELRELEKVLKkeSELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKliklKGEIKSLKKE 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1034 FEKNKAVQTALDEFKVERELVEKELLEKVKHLENQiaktpAFESAREDSSSLvAELQ------------EKLQEEKAKFL 1101
Cdd:PRK03918 548 LEKLEELKKKLAELEKKLDELEEELAELLKELEEL-----GFESVEELEERL-KELEpfyneylelkdaEKELEREEKEL 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1102 EQLEEQEKRKNEEMQNVRTSL------IAEQQTNFNTV----LTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSE 1171
Cdd:PRK03918 622 KKLEEELDKAFEELAETEKRLeelrkeLEELEKKYSEEeyeeLREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701
|
...
gi 1907067116 1172 DRA 1174
Cdd:PRK03918 702 ELE 704
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
687-1017 |
8.22e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.54 E-value: 8.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 687 EENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKimhtqhcEIKELKQSREMALEDLKKL 766
Cdd:TIGR02168 680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRK-------DLARLEAEVEQLEERIAQL 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 767 HDEkIESLRAEFQCLEQNhLKELEDTLHirhtqefekvmtdhnmSLEKLKKENQQRIDQMLESHA---STIQEKEQQLQE 843
Cdd:TIGR02168 753 SKE-LTELEAEIEELEER-LEEAEEELA----------------EAEAEIEELEAQIEQLKEELKalrEALDELRAELTL 814
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 844 LKLKVSDLsdmRCKLEVELALKEAETDEIKILLEESRTQQKEMLKslLEQETENLRTEISKLNQKIHDNNESYQVgLSEL 923
Cdd:TIGR02168 815 LNEEAANL---RERLESLERRIAATERRLEDLEEQIEELSEDIES--LAAEIEELEELIEELESELEALLNERAS-LEEA 888
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 924 RALMTIEKDQCISElISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALE---KQKDEKITQQE 1000
Cdd:TIGR02168 889 LALLRSELEELSEE-LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLeeaEALENKIEDDE 967
|
330
....*....|....*..
gi 1907067116 1001 EKYEALIQNLEKDKERL 1017
Cdd:TIGR02168 968 EEARRRLKRLENKIKEL 984
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
944-1175 |
9.65e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.42 E-value: 9.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 944 EESNILKAELdnvTSLHRQAYEIE-KKLKEQIVELQTRLNSELSALEkQKDEKITQQEEKYEALIQNLEKDKERLVkNHE 1022
Cdd:COG1196 220 EELKELEAEL---LLLKLRELEAElEELEAELEELEAELEELEAELA-ELEAELEELRLELEELELELEEAQAEEY-ELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1023 QDKEHLIQELNF--EKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKF 1100
Cdd:COG1196 295 AELARLEQDIARleERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907067116 1101 LEQLEEQEKRKNEEMQNVRTSL-IAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
834-1127 |
1.88e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 62.39 E-value: 1.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 834 IQEKEQQLQELKLKVSDLSDMRCKLEVELALKEaetdEIKILLEESR-TQQKEMLKSL--LEQETENLRTEISKLNQKIh 910
Cdd:TIGR02169 179 LEEVEENIERLDLIIDEKRQQLERLRREREKAE----RYQALLKEKReYEGYELLKEKeaLERQKEAIERQLASLEEEL- 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 911 dnnESYQVGLSELRALMTiEKDQCISELISR----HEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELS 986
Cdd:TIGR02169 254 ---EKLTEEISELEKRLE-EIEQLLEELNKKikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 987 ALEKQK------DEKITQQEEKYEALIQNLEKDKERL----VKNHEQDKEHliQELnFEKNKAVQTALDEFKVERELVEK 1056
Cdd:TIGR02169 330 EIDKLLaeieelEREIEEERKRRDKLTEEYAELKEELedlrAELEEVDKEF--AET-RDELKDYREKLEKLKREINELKR 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1057 E----------LLEKVKHLENQIA----KTPAFESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRTSL 1122
Cdd:TIGR02169 407 EldrlqeelqrLSEELADLNAAIAgieaKINELEEEKEDKALEIKKQEWKLEQLAAD-LSKYEQELYDLKEEYDRVEKEL 485
|
....*
gi 1907067116 1123 IAEQQ 1127
Cdd:TIGR02169 486 SKLQR 490
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
644-1116 |
2.10e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 62.39 E-value: 2.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 644 EIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKLdalvkdseenvNKILKLKENLVSLEEALQNKDNEFTSIKHEKda 723
Cdd:PRK03918 274 EIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL-----------REIEKRLSRLEEEINGIEERIKELEEKEERL-- 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 724 ivcvqQEKDQKLLEMEKimhtqhcEIKELKQSREmALEDLKKLHDEkIESLRAEFQCLEQNHLKELEDTLHIRHT--QEF 801
Cdd:PRK03918 341 -----EELKKKLKELEK-------RLEELEERHE-LYEEAKAKKEE-LERLKKRLTGLTPEKLEKELEELEKAKEeiEEE 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 802 EKVMTDHNMSLEKLKKENQQRIDQMLESHAS--------TIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIK 873
Cdd:PRK03918 407 ISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELE 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 874 ILLEESRTQQKemLKSLLEQeTENLRTEISKLNqkihdnnesyqvglselralmtIEKDQCISELISRHEEESNILKAEL 953
Cdd:PRK03918 487 KVLKKESELIK--LKELAEQ-LKELEEKLKKYN----------------------LEELEKKAEEYEKLKEKLIKLKGEI 541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 954 DNVTSLHRQAYEIEKKLKEQIVELQTrLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLV--KNHEQDKEHLIQE 1031
Cdd:PRK03918 542 KSLKKELEKLEELKKKLAELEKKLDE-LEEELAELLKELEELGFESVEELEERLKELEPFYNEYLelKDAEKELEREEKE 620
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1032 LNFEKNKAVQTA--LDEFKVERELVEKEL--LEKVKHLENQIAKTPAFESAREDSSSLVAELQ--EKLQEEKAKFLEQLE 1105
Cdd:PRK03918 621 LKKLEEELDKAFeeLAETEKRLEELRKELeeLEKKYSEEEYEELREEYLELSRELAGLRAELEelEKRREEIKKTLEKLK 700
|
490
....*....|..
gi 1907067116 1106 EQ-EKRKNEEMQ 1116
Cdd:PRK03918 701 EElEEREKAKKE 712
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
916-1175 |
2.95e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.88 E-value: 2.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 916 YQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALE--KQKD 993
Cdd:COG1196 218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYelLAEL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 994 EKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQ-----ELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQ 1068
Cdd:COG1196 298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEEleeelEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1069 IAKTPAFESAREDSSSLVAELQEKLQ------EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQT--NFNTVLTREKMR 1140
Cdd:COG1196 378 EEELEELAEELLEALRAAAELAAQLEeleeaeEALLERLERLEEELEELEEALAELEEEEEEEEEAleEAAEEEAELEEE 457
|
250 260 270
....*....|....*....|....*....|....*
gi 1907067116 1141 KENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:COG1196 458 EEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
631-1017 |
4.38e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 61.24 E-value: 4.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 631 QCDLANYLKCTAVEIRNIIEKVkcsleitlkekhqqelqSLKIEYECKLDALVKDSEEnvnkilkLKENLVSLEEALQNK 710
Cdd:TIGR02169 141 QGDVTDFISMSPVERRKIIDEI-----------------AGVAEFDRKKEKALEELEE-------VEENIERLDLIIDEK 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 711 DNEFTSIKHEKDaivcvQQEKDQKLLEmEKimhtQHCEIKELKQSREMALEDLKKLhDEKIESLRAEFQCLEQnHLKELE 790
Cdd:TIGR02169 197 RQQLERLRRERE-----KAERYQALLK-EK----REYEGYELLKEKEALERQKEAI-ERQLASLEEELEKLTE-EISELE 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 791 DTLHirhtqEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETD 870
Cdd:TIGR02169 265 KRLE-----EIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE 339
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 871 EIKillEESRTQQKEmlKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALmtiekDQCISELISRHEEesniLK 950
Cdd:TIGR02169 340 ELE---REIEEERKR--RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDY-----REKLEKLKREINE----LK 405
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907067116 951 AELDNVTSLHRQAYEIEKKLKEQIVELQTRLNsELSALEKQKDEKITQQEEKYEALIQNLEKDKERL 1017
Cdd:TIGR02169 406 RELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
748-1281 |
4.55e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.11 E-value: 4.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 748 EIKELKQSREMALEDLKKLhDEKIESLRAEFQCLE------QNHLKELEDTLHIRHTQEFEKVMTDHNM-----SLEKLK 816
Cdd:COG1196 233 KLRELEAELEELEAELEEL-EAELEELEAELAELEaeleelRLELEELELELEEAQAEEYELLAELARLeqdiaRLEERR 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 817 KENQQRIDQMLEShastIQEKEQQLQELKLKvsdlsdmrcklEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETE 896
Cdd:COG1196 312 RELEERLEELEEE----LAELEEELEELEEE-----------LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 897 NLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQcisELISRHEEESNILKAELDNVtslhRQAYEIEKKLKEQIVE 976
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALL---ERLERLEEELEELEEALAEL----EEEEEEEEEALEEAAE 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 977 LQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLvknheqdkehliQELNFEKNKAVQTALDEFKVERELVEK 1056
Cdd:COG1196 450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA------------ARLLLLLEAEADYEGFLEGVKAALLLA 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1057 ELLEKVKHLENQIAKTPAFESAREDssSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTR 1136
Cdd:COG1196 518 GLRGLAGAVAVLIGVEAAYEAALEA--ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARG 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1137 EKMRKENIINDLSDKLKStmqQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLSSApVAAAPELYGACAPELP 1216
Cdd:COG1196 596 AIGAAVDLVASDLREADA---RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG-GSAGGSLTGGSRRELL 671
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907067116 1217 GEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLKRMEH 1281
Cdd:COG1196 672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE 736
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
892-1172 |
5.07e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.23 E-value: 5.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 892 EQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKD-----QCISELISRHEEESNILKAELDNVTSLHRQAYEI 966
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQlrkelEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 967 EKKLKEQIVELQTRLNsELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEH--LIQELNFEKNKAVQTAL 1044
Cdd:TIGR02168 756 LTELEAEIEELEERLE-EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLneEAANLRERLESLERRIA 834
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1045 DEFKVERELVE--KELLEKVKHLENQIAKT----PAFESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNV 1118
Cdd:TIGR02168 835 ATERRLEDLEEqiEELSEDIESLAAEIEELeeliEELESELEALLNERASLEEALALLRSE-LEELSEELRELESKRSEL 913
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1907067116 1119 RTSLIA--EQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSED 1172
Cdd:TIGR02168 914 RRELEElrEKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
657-1171 |
5.35e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 61.22 E-value: 5.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 657 EITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVsleealQNKDNEFTSIKHEKDAIVCVQQEKDQKLL 736
Cdd:TIGR00606 270 EIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTV------REKERELVDCQRELEKLNKERRLLNQEKT 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 737 EMEKimhtqhcEIKELKQSREMALEDLKKLHDEKIE-SLRAEFQCLEQNHLKELE-DTLH--IRHTQEFEKVMTDHNM-- 810
Cdd:TIGR00606 344 ELLV-------EQGRLQLQADRHQEHIRARDSLIQSlATRLELDGFERGPFSERQiKNFHtlVIERQEDEAKTAAQLCad 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 811 --SLEKLKKENQQRIDQMLESHASTIQEK----EQQLQELKLKVSDLSD----MRCKLEVELALKEAETDeIKILLEESR 880
Cdd:TIGR00606 417 lqSKERLKQEQADEIRDEKKGLGRTIELKkeilEKKQEELKFVIKELQQlegsSDRILELDQELRKAERE-LSKAEKNSL 495
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 881 TQQKEMLKSLLEQETENLRTEISKLNQKIHD-NNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSL 959
Cdd:TIGR00606 496 TETLKKEVKSLQNEKADLDRKLRKLDQEMEQlNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQL 575
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 960 HRQAYEIEKKLKeQIVELQTRLNSELSALEKQKD------EKITQQEEKYEALI------QNLEKDKERLVKNHEQDKEH 1027
Cdd:TIGR00606 576 EDWLHSKSKEIN-QTRDRLAKLNKELASLEQNKNhinnelESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQ 654
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1028 L-------------IQELNFEKNKAVQTALDEFKVERELVE--KELLEKVKHLENQIAKTPAFESAREDSSSLV---AEL 1089
Cdd:TIGR00606 655 RamlagatavysqfITQLTDENQSCCPVCQRVFQTEAELQEfiSDLQSKLRLAPDKLKSTESELKKKEKRRDEMlglAPG 734
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1090 QEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSlIAEQQTNFNTVLTREKMrKENIINDLSDKLKSTMQQQERDKDLIESL 1169
Cdd:TIGR00606 735 RQSIIDLKEKEIPELRNKLQKVNRDIQRLKND-IEEQETLLGTIMPEEES-AKVCLTDVTIMERFQMELKDVERKIAQQA 812
|
..
gi 1907067116 1170 SE 1171
Cdd:TIGR00606 813 AK 814
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
661-1191 |
6.10e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.84 E-value: 6.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 661 KEKHQQELQSLKIEYEckldALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEK 740
Cdd:TIGR02168 304 KQILRERLANLERQLE----ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 741 IMHTQHCEIKELKQSREMALEDLKKLhDEKIESLRAEFQCLEQNhLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQ 820
Cdd:TIGR02168 380 QLETLRSKVAQLELQIASLNNEIERL-EARLERLEDRRERLQQE-IEELLKKLEEAELKELQAELEELEEELEELQEELE 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 821 QRIDQmLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESR--TQQKEMLKSLLEQEtENL 898
Cdd:TIGR02168 458 RLEEA-LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSglSGILGVLSELISVD-EGY 535
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 899 RTEISK-----LNQKIHDNNESYQVGLSELR--------------------------ALMTIEKDQCI-SELISRHEEES 946
Cdd:TIGR02168 536 EAAIEAalggrLQAVVVENLNAAKKAIAFLKqnelgrvtflpldsikgteiqgndreILKNIEGFLGVaKDLVKFDPKLR 615
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 947 NILKAELDNV------------------------------------------TSLHRQAYEIE--------KKLKEQIVE 976
Cdd:TIGR02168 616 KALSYLLGGVlvvddldnalelakklrpgyrivtldgdlvrpggvitggsakTNSSILERRREieeleekiEELEEKIAE 695
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 977 LQTRLN---SELSALEKQKDEKITQQEEKyEALIQNLEKDKERLVKNHEQdKEHLIQELNFEKNKAVQ--TALDEFKVER 1051
Cdd:TIGR02168 696 LEKALAelrKELEELEEELEQLRKELEEL-SRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAeiEELEERLEEA 773
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1052 ELVEKELLEKVKHLENQIAKtpaFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNE----EMQNVRTSLIAEQQ 1127
Cdd:TIGR02168 774 EEELAEAEAEIEELEAQIEQ---LKEELKALREALDELRAELTLLNEEAANLRERLESLERRiaatERRLEDLEEQIEEL 850
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907067116 1128 TNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLR 1191
Cdd:TIGR02168 851 SEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELR 914
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
644-1175 |
6.64e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.84 E-value: 6.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 644 EIRNIIEKVKCSLEITLKEKHQQELQSLKIEYEC-----KLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEftsik 718
Cdd:TIGR02168 292 ALANEISRLEQQKQILRERLANLERQLEELEAQLeelesKLDELAEELAELEEKLEELKEELESLEAELEELEAE----- 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 719 hekdaivcvQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLhDEKIESLRAEFQCLEQNhLKELEDTLHIRHT 798
Cdd:TIGR02168 367 ---------LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL-EARLERLEDRRERLQQE-IEELLKKLEEAEL 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 799 QEFEKVMTDHNMSLEKLKKENQQRIDQmLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEE 878
Cdd:TIGR02168 436 KELQAELEELEEELEELQEELERLEEA-LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 879 SR--TQQKEMLKSLLEQEtENLRTEISK-----LNQKIHDNNESYQVGLSELR--------------------------A 925
Cdd:TIGR02168 515 QSglSGILGVLSELISVD-EGYEAAIEAalggrLQAVVVENLNAAKKAIAFLKqnelgrvtflpldsikgteiqgndreI 593
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 926 LMTIEKDQCI-SELISRHEEESNILKAELDN---VTSLhRQAYEIEKKLKEQ--IVELQTRL------------NSELSA 987
Cdd:TIGR02168 594 LKNIEGFLGVaKDLVKFDPKLRKALSYLLGGvlvVDDL-DNALELAKKLRPGyrIVTLDGDLvrpggvitggsaKTNSSI 672
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 988 LEKQKD-EKITQQEEKYEALIQNLEKDKERLVKNHEQDKE--HLIQELNFEKNK---AVQTALDEFKVERELVEKELLEK 1061
Cdd:TIGR02168 673 LERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEelEQLRKELEELSRqisALRKDLARLEAEVEQLEERIAQL 752
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1062 VKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKF------LEQLEEQEKRKNEEMQNVRTSliAEQQTNFNTVLT 1135
Cdd:TIGR02168 753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlkeeLKALREALDELRAELTLLNEE--AANLRERLESLE 830
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 1907067116 1136 REKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:TIGR02168 831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
731-1169 |
9.58e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 60.03 E-value: 9.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 731 KDQKLLEMEKIMHTQHCEIKElKQSREMALEDLKKLHDEKIESLRAEFQCLEQNhLKELEDTLHIRHTQefekvMTDHNM 810
Cdd:TIGR04523 31 QDTEEKQLEKKLKTIKNELKN-KEKELKNLDKNLNKDEEKINNSNNKIKILEQQ-IKDLNDKLKKNKDK-----INKLNS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 811 SLEKLKKENQQRIDQMLESHaSTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSL 890
Cdd:TIGR04523 104 DLSKINSEIKNDKEQKNKLE-VELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEK 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 891 LEQETE--NLRTEISKLNQKIHD------NNESYQVGLSELRALMTIEKDQcISELISRHEEESNILKAELDNVTSLHRQ 962
Cdd:TIGR04523 183 LNIQKNidKIKNKLLKLELLLSNlkkkiqKNKSLESQISELKKQNNQLKDN-IEKKQQEINEKTTEISNTQTQLNQLKDE 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 963 AYEIEKKLKEQIVELQT-------------RLNSELSALEKQKD--------EKITQQEEKYEALIQNLEKDKERLVKNH 1021
Cdd:TIGR04523 262 QNKIKKQLSEKQKELEQnnkkikelekqlnQLKSEISDLNNQKEqdwnkelkSELKNQEKKLEEIQNQISQNNKIISQLN 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1022 EQ--DKEHLIQELNFEkNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDssslvaelQEKLQEEKAK 1099
Cdd:TIGR04523 342 EQisQLKKELTNSESE-NSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQN--------QEKLNQQKDE 412
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1100 FLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNtvLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESL 1169
Cdd:TIGR04523 413 QIKKLQQEKELLEKEIERLKETIIKNNSEIKD--LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKI 480
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
606-1192 |
1.13e-08 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 60.07 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 606 AQDSHSSIQTIKDDLCH--FRTFVQKEQCDLANYLKCTAVEIRNIIEKVkcsleitlkEKHQQELQSLKIEYECKLDAL- 682
Cdd:TIGR01612 1079 AEINITNFNEIKEKLKHynFDDFGKEENIKYADEINKIKDDIKNLDQKI---------DHHIKALEEIKKKSENYIDEIk 1149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 683 --------VKD---SEENVNKILKLKENLVSleeALQNKDNEFTSIKHEKDAIVCVqqEKDQKLLEMEKIMHTQHCeiKE 751
Cdd:TIGR01612 1150 aqindledVADkaiSNDDPEEIEKKIENIVT---KIDKKKNIYDEIKKLLNEIAEI--EKDKTSLEEVKGINLSYG--KN 1222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 752 LKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKenQQRIDQMLESHA 831
Cdd:TIGR01612 1223 LGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKD--HHIISKKHDENI 1300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 832 STIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESrTQQKEMLKSlleQETENLRTEISKLNQKIHD 911
Cdd:TIGR01612 1301 SDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEI-ANIYNILKL---NKIKKIIDEVKEYTKEIEE 1376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 912 NNESYQVGLSELRALMTIEKD-----QC------------ISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQI 974
Cdd:TIGR01612 1377 NNKNIKDELDKSEKLIKKIKDdinleECkskiestlddkdIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLF 1456
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 975 VELQTRLNSELSALEKQKDEKITQQEEKYEALIQNleKDKERLVKNhEQDKehliQELNFEKNKAVqtaldeFKVERELV 1054
Cdd:TIGR01612 1457 KNIEMADNKSQHILKIKKDNATNDHDFNINELKEH--IDKSKGCKD-EADK----NAKAIEKNKEL------FEQYKKDV 1523
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1055 eKELLEKVKHLE--NQIAKTpafesaREDSSSLVAELQEKlqeeKAKFLEQLEEQEKR----KNEEMQ------------ 1116
Cdd:TIGR01612 1524 -TELLNKYSALAikNKFAKT------KKDSEIIIKEIKDA----HKKFILEAEKSEQKikeiKKEKFRieddaakndksn 1592
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1117 ----NVRTSL---------IAEQQTNFNTVLTREKMRKENI----INDLSDKLKSTMQQQERDKDLIESLSEDRARLLEE 1179
Cdd:TIGR01612 1593 kaaiDIQLSLenfenkflkISDIKKKINDCLKETESIEKKIssfsIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDK 1672
|
650
....*....|...
gi 1907067116 1180 KKQLEEEVSKLRT 1192
Cdd:TIGR01612 1673 KKELDELDSEIEK 1685
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
949-1195 |
1.25e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.69 E-value: 1.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 949 LKAELDNVTSLHRQAYEIEKKLKEQIVELQ---TRLNSELSALEKQKDEkitQQEEKYE--ALIQNLEKDKERLV---KN 1020
Cdd:TIGR02168 237 LREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEE---LQKELYAlaNEISRLEQQKQILRerlAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1021 HEQDKEHLIQELNFEKNKavqtaLDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKF 1100
Cdd:TIGR02168 314 LERQLEELEAQLEELESK-----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1101 LeQLEEQEKRKNEEMQNVRTSL--IAEQQTNFNTVLT-----REKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDR 1173
Cdd:TIGR02168 389 A-QLELQIASLNNEIERLEARLerLEDRRERLQQEIEellkkLEEAELKELQAELEELEEELEELQEELERLEEALEELR 467
|
250 260
....*....|....*....|..
gi 1907067116 1174 ARLLEEKKQLEEEVSKLRTSSF 1195
Cdd:TIGR02168 468 EELEEAEQALDAAERELAQLQA 489
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
814-1093 |
1.94e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.24 E-value: 1.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 814 KLKKENQQRIDQMLEShastIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAEtdeikilLEESRTQQKEmlkslLEQ 893
Cdd:COG4942 20 DAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQLAALERRIAALARR-------IRALEQELAA-----LEA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 894 ETENLRTEISKLNQKIHDNNESYQvglSELRALMTiekdqciselISRHEEESNILKAElDNVTSLHRQAY--EIEKKLK 971
Cdd:COG4942 84 ELAELEKEIAELRAELEAQKEELA---ELLRALYR----------LGRQPPLALLLSPE-DFLDAVRRLQYlkYLAPARR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 972 EQIVELQTRLNsELSALEKQkdekITQQEEKYEALIQNLEKDKERLVKNhEQDKEHLIQELNfEKNKAVQTALDEFKVEr 1051
Cdd:COG4942 150 EQAEELRADLA-ELAALRAE----LEAERAELEALLAELEEERAALEAL-KAERQKLLARLE-KELAELAAELAELQQE- 221
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1907067116 1052 elvEKELLEKVKHLENQIAktpafESAREDSSSLVAELQEKL 1093
Cdd:COG4942 222 ---AEELEALIARLEAEAA-----AAAERTPAAGFAALKGKL 255
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
694-1045 |
2.86e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.54 E-value: 2.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 694 LKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLH------ 767
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEedlssl 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 768 DEKIESLRAEFQCLEQ---------NHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQR---IDQMLESHASTIQ 835
Cdd:TIGR02169 750 EQEIENVKSELKELEArieeleedlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARlreIEQKLNRLTLEKE 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 836 EKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSL--LEQETENLRTEISKLNQKIHDNN 913
Cdd:TIGR02169 830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLgdLKKERDELEAQLRELERKIEELE 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 914 ESYQvgLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLhrqayeiekklkEQIVELQTRLNSELSALEKQKD 993
Cdd:TIGR02169 910 AQIE--KKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL------------EDVQAELQRVEEEIRALEPVNM 975
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1907067116 994 EKITQQEEKYEALiQNLEKDKERLVKNHEQDKEhLIQELNFEKNKAVQTALD 1045
Cdd:TIGR02169 976 LAIQEYEEVLKRL-DELKEKRAKLEEERKAILE-RIEEYEKKKREVFMEAFE 1025
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
694-1173 |
1.19e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 56.65 E-value: 1.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 694 LKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDekies 773
Cdd:pfam05483 215 FKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIE----- 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 774 lraefqclEQNHL-KELEDTlhirhtqefeKVMTDHNMSLEKLKKENQQ----RIDQMLESHASTIQEKEQQLQELKLKV 848
Cdd:pfam05483 290 --------KKDHLtKELEDI----------KMSLQRSMSTQKALEEDLQiatkTICQLTEEKEAQMEELNKAKAAHSFVV 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 849 SDLSDMRCKLE----VELALKEAETDEIKILLEESRTQQKEM-----LKSLLEQETENLRTEISKlNQKIHDNNESYQVG 919
Cdd:pfam05483 352 TEFEATTCSLEellrTEQQRLEKNEDQLKIITMELQKKSSELeemtkFKNNKEVELEELKKILAE-DEKLLDEKKQFEKI 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 920 LSELRAlmtieKDQCISELISRHEEESNILKAELdNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQ---KDEKI 996
Cdd:pfam05483 431 AEELKG-----KEQELIFLLQAREKEIHDLEIQL-TAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKlllENKEL 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 997 TQQEEKyeaLIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAvqtaldEFKVERELVEKELLEKVKHLENQIAKTPafE 1076
Cdd:pfam05483 505 TQEASD---MTLELKKHQEDIINCKKQEERMLKQIENLEEKEM------NLRDELESVREEFIQKGDEVKCKLDKSE--E 573
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1077 SARE-DSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEqqtnfNTVLTREKMRKENIINDLSDKLKST 1155
Cdd:pfam05483 574 NARSiEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKK-----GSAENKQLNAYEIKVNKLELELASA 648
|
490
....*....|....*...
gi 1907067116 1156 MQQQERDKDLIESLSEDR 1173
Cdd:pfam05483 649 KQKFEEIIDNYQKEIEDK 666
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
728-1061 |
1.24e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.60 E-value: 1.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 728 QQEKDQKLLEMEKimhtqhcEIKELKqsREMALEDLKKLHdEKIESLRAEFQCLEQNHlKELEDTLHIRHTQEFEKVMTD 807
Cdd:TIGR02168 208 QAEKAERYKELKA-------ELRELE--LALLVLRLEELR-EELEELQEELKEAEEEL-EELTAELQELEEKLEELRLEV 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 808 HNMSleklkkENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEML 887
Cdd:TIGR02168 277 SELE------EEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 888 KSL--LEQETENLRTEISKLNQKIHDNNESYQvGLSELRALMTIEKDQcISELISRHEEESNILKAELDNvtsLHRQAYE 965
Cdd:TIGR02168 351 EELesLEAELEELEAELEELESRLEELEEQLE-TLRSKVAQLELQIAS-LNNEIERLEARLERLEDRRER---LQQEIEE 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 966 IEKKLKE-QIVELQTRLNselsalekQKDEKITQQEEKYEALIQNLEKDKERLVKNHE--QDKEHLIQELNFEKnKAVQT 1042
Cdd:TIGR02168 426 LLKKLEEaELKELQAELE--------ELEEELEELQEELERLEEALEELREELEEAEQalDAAERELAQLQARL-DSLER 496
|
330
....*....|....*....
gi 1907067116 1043 ALDEFKVERELVEKELLEK 1061
Cdd:TIGR02168 497 LQENLEGFSEGVKALLKNQ 515
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
811-1017 |
1.37e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.54 E-value: 1.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 811 SLEKLKKENQQRIDQM---LESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAEtdeikilLEESRTQQKEml 887
Cdd:COG4942 24 EAEAELEQLQQEIAELekeLAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE-------LAELEKEIAE-- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 888 kslLEQETENLRTEISKLNQKI--HDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYE 965
Cdd:COG4942 95 ---LRAELEAQKEELAELLRALyrLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1907067116 966 IEKKLKEQIVELQTRLNsELSALEKQKDE---KITQQEEKYEALIQNLEKDKERL 1017
Cdd:COG4942 172 ERAELEALLAELEEERA-ALEALKAERQKllaRLEKELAELAAELAELQQEAEEL 225
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
661-1175 |
1.41e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 56.34 E-value: 1.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 661 KEKHQQELQSLKiEYECKLDALVKDSEENVNKILKLKENLVSLEEA---LQNKDNEFTSIKHEKDAIVCVQQEKDQKLLE 737
Cdd:pfam01576 18 KERQQKAESELK-ELEKKHQQLCEEKNALQEQLQAETELCAEAEEMrarLAARKQELEEILHELESRLEEEEERSQQLQN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 738 MEKIMHTQHCEIKELKQSREMALEDL---KKLHDEKIESLRAEFQCLE-QNHLKELEDTLHIRHTQEFEKVMTDHN---M 810
Cdd:pfam01576 97 EKKKMQQHIQDLEEQLDEEEAARQKLqleKVTTEAKIKKLEEDILLLEdQNSKLSKERKLLEERISEFTSNLAEEEekaK 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 811 SLEKLKKENQQRIDQM---LESHASTIQEKEQ-------QLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESR 880
Cdd:pfam01576 177 SLSKLKNKHEAMISDLeerLKKEEKGRQELEKakrklegESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEET 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 881 TQQKEMLKSL---------LEQETENLRTEISKLNQKIHDNNEsyqvglsELRALMTIEKDQCIS-----ELISRHEEES 946
Cdd:pfam01576 257 AQKNNALKKIreleaqiseLQEDLESERAARNKAEKQRRDLGE-------ELEALKTELEDTLDTtaaqqELRSKREQEV 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 947 NILKAELDNVTSLHR-QAYEIEKKLKEQIVELQTRLnsELSALEKQKDEKITQQEEKyealiQNLEKDKE-RLVKNHEQD 1024
Cdd:pfam01576 330 TELKKALEEETRSHEaQLQEMRQKHTQALEELTEQL--EQAKRNKANLEKAKQALES-----ENAELQAElRTLQQAKQD 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1025 KEHliqelnfeKNKAVQTALDEFKV---ERELVEKELLEKVKHLENQIAKTPAFESARED----SSSLVAELQEKLQEEK 1097
Cdd:pfam01576 403 SEH--------KRKKLEGQLQELQArlsESERQRAELAEKLSKLQSELESVSSLLNEAEGknikLSKDVSSLESQLQDTQ 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1098 akflEQLEEQEKRKNEEMQNVRTslIAEQQTNFNTVLTREKMRKENI---INDLSDKLKSTMQQQERDKDLIESLSEDRA 1174
Cdd:pfam01576 475 ----ELLQEETRQKLNLSTRLRQ--LEDERNSLQEQLEEEEEAKRNVerqLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548
|
.
gi 1907067116 1175 R 1175
Cdd:pfam01576 549 R 549
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
644-1278 |
2.11e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 55.75 E-value: 2.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 644 EIRNIIEKvKCSLEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDA 723
Cdd:pfam02463 398 ELKSEEEK-EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKE 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 724 IVCVQQEkdQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEfek 803
Cdd:pfam02463 477 TQLVKLQ--EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIV--- 551
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 804 vmTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEI------KILLE 877
Cdd:pfam02463 552 --EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDdkrakvVEGIL 629
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 878 ESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVT 957
Cdd:pfam02463 630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 958 SLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQkdeKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKN 1037
Cdd:pfam02463 710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQ---KIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKL 786
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1038 KAVQTaLDEFKVERELVEKELLEKVKHLENQIAktpafESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQN 1117
Cdd:pfam02463 787 KVEEE-KEEKLKAQEEELRALEEELKEEAELLE-----EEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLE 860
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1118 VRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFLS 1197
Cdd:pfam02463 861 EEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL 940
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1198 SAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLK 1277
Cdd:pfam02463 941 LLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
|
.
gi 1907067116 1278 R 1278
Cdd:pfam02463 1021 E 1021
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
599-1116 |
2.61e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 55.36 E-value: 2.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 599 LEKCRAAAQDSHSSIQTIKDDLCHFRtfVQKEQCDLANYLKCTAVEIRNIIEKVKCSLEiTLKEKHQQELQSLKIEYECK 678
Cdd:TIGR00618 333 HVKQQSSIEEQRRLLQTLHSQEIHIR--DAHEVATSIREISCQQHTLTQHIHTLQQQKT-TLTQKLQSLCKELDILQREQ 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 679 LDALVKDSEENVNKILKL------KENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQ---EKDQKLLEMEKImHTQHCEI 749
Cdd:TIGR00618 410 ATIDTRTSAFRDLQGQLAhakkqqELQQRYAELCAAAITCTAQCEKLEKIHLQESAQslkEREQQLQTKEQI-HLQETRK 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 750 KELKQSREMALEDLKKLHDEKIESLRAEFQCL-----EQNHLKELEDTlHIRHTQEFEKVMTDHNMSLEKLK--KENQQR 822
Cdd:TIGR00618 489 KAVVLARLLELQEEPCPLCGSCIHPNPARQDIdnpgpLTRRMQRGEQT-YAQLETSEEDVYHQLTSERKQRAslKEQMQE 567
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 823 IDQMLESHASTIQE----------KEQQLQELKLKVSDLSDM-RCKLEVELALKEAETDEIKILLEESRTQQKEMLKSL- 890
Cdd:TIGR00618 568 IQQSFSILTQCDNRskedipnlqnITVRLQDLTEKLSEAEDMlACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTa 647
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 891 LEQETENLRTEisklNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESN----ILKAELDNVTSLHRQAYEI 966
Cdd:TIGR00618 648 LHALQLTLTQE----RVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAqcqtLLRELETHIEEYDREFNEI 723
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 967 EKKLKEQIVELQTR---LNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLvknheQDKEHLIQELNFeKNKAVQTA 1043
Cdd:TIGR00618 724 ENASSSLGSDLAARedaLNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTG-----AELSHLAAEIQF-FNRLREED 797
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907067116 1044 LDEFKVERELVEKELLEKVKHLENQIAKtpaFESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQ 1116
Cdd:TIGR00618 798 THLLKTLEAEIGQEIPSDEDILNLQCET---LVQEEEQFLSRLEEKSATLGEITHQ-LLKYEECSKQLAQLTQ 866
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
653-1172 |
3.59e-07 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 54.75 E-value: 3.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 653 KCSLEITLKEKHQQELQ--SLKIEYECKLDALVKDSEENVNK-------ILKLKENLVSLEEALQNKDNEFTSIKHEKDA 723
Cdd:pfam05557 8 KARLSQLQNEKKQMELEhkRARIELEKKASALKRQLDRESDRnqelqkrIRLLEKREAEAEEALREQAELNRLKKKYLEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 724 IVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMAledlkklhDEKIESLRAEFQCLEQNHlKELEDTLhirhtQEFEK 803
Cdd:pfam05557 88 LNKKLNEKESQLADAREVISCLKNELSELRRQIQRA--------ELELQSTNSELEELQERL-DLLKAKA-----SEAEQ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 804 VMTDHNMSLEKLKKENQ--QRIDQMLESHASTIQEKEQQLQELkLKVSDLSDMRCKLEVELAlKEAETDEIKILLEEsrt 881
Cdd:pfam05557 154 LRQNLEKQQSSLAEAEQriKELEFEIQSQEQDSEIVKNSKSEL-ARIPELEKELERLREHNK-HLNENIENKLLLKE--- 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 882 qQKEMLKSLLEQETE------NLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDqcISELISR---HEEESNILKAE 952
Cdd:pfam05557 229 -EVEDLKRKLEREEKyreeaaTLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRR--IEQLQQReivLKEENSSLTSS 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 953 LDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKyEALIQNLEK-DKERLVKNHEQDKEHLIQE 1031
Cdd:pfam05557 306 ARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKER-DGYRAILESyDKELTMSNYSPQLLERIEE 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1032 LNFEKNKaVQTALDEFKVERELVEKELL---EKVKHLENQIAKTPAFESAREDSSSL--VAELQEKLQEEKAkfleQLEE 1106
Cdd:pfam05557 385 AEDMTQK-MQAHNEEMEAQLSVAEEELGgykQQAQTLERELQALRQQESLADPSYSKeeVDSLRRKLETLEL----ERQR 459
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907067116 1107 QEKRKNE-EMQNVRTSLiaeqQTNFNTVLTREKMRKENIINDLSDKLKSTMQQ----QERDKDLIESLSED 1172
Cdd:pfam05557 460 LREQKNElEMELERRCL----QGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKlqaeIERLKRLLKKLEDD 526
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
674-955 |
4.71e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.68 E-value: 4.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 674 EYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKL--LEMEKIMHTQ------ 745
Cdd:TIGR02168 236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIsrLEQQKQILRErlanle 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 746 ------HCEIKELKQSREMALEDLKKLhDEKIESLRAEFQcLEQNHLKELEDTLhirhtQEFEKVMTDHNMSLEKLKKEN 819
Cdd:TIGR02168 316 rqleelEAQLEELESKLDELAEELAEL-EEKLEELKEELE-SLEAELEELEAEL-----EELESRLEELEEQLETLRSKV 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 820 QQRIDQmLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVElaLKEAETDEIKILLEESRTQQKEMLKSL--LEQETEN 897
Cdd:TIGR02168 389 AQLELQ-IASLNNEIERLEARLERLEDRRERLQQEIEELLKK--LEEAELKELQAELEELEEELEELQEELerLEEALEE 465
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907067116 898 LRTEISKLNQKIHDNNESYQVGLSELRALMTIEkdqciseliSRHEEESNILKAELDN 955
Cdd:TIGR02168 466 LREELEEAEQALDAAERELAQLQARLDSLERLQ---------ENLEGFSEGVKALLKN 514
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
703-1122 |
6.14e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.00 E-value: 6.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 703 LEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKlhdeKIESLRAEFQCLE 782
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEA----ELEELREELEKLE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 783 QnhLKELEDTLHIRhtQEFEKVMTDHNMSLEKLKKENQQRIDQM--LESHASTIQEKEQQLQELKLKVSdlsdmrckLEV 860
Cdd:COG4717 123 K--LLQLLPLYQEL--EALEAELAELPERLEELEERLEELRELEeeLEELEAELAELQEELEELLEQLS--------LAT 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 861 ELALKEAETDEIKilLEESRTQQKEMLKSlLEQETENLRTEISKLNQKIHDNNESYQvgLSELRALMTI-----EKDQCI 935
Cdd:COG4717 191 EEELQDLAEELEE--LQQRLAELEEELEE-AQEELEELEEELEQLENELEAAALEER--LKEARLLLLIaaallALLGLG 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 936 SELISRHEEESNILKAEL----DNVTSLHRQAYEIEKKLKE--QIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQN 1009
Cdd:COG4717 266 GSLLSLILTIAGVLFLVLgllaLLFLLLAREKASLGKEAEElqALPALEELEEEELEELLAALGLPPDLSPEELLELLDR 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1010 LEKDKERLVKNHEQDKEHLIQELNFEKN----KAVQTALDEF--KVERELVEKELLEKVKHLENQIAKTPAFESAREDSS 1083
Cdd:COG4717 346 IEELQELLREAEELEEELQLEELEQEIAallaEAGVEDEEELraALEQAEEYQELKEELEELEEQLEELLGELEELLEAL 425
|
410 420 430
....*....|....*....|....*....|....*....
gi 1907067116 1084 SLvAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRTSL 1122
Cdd:COG4717 426 DE-EELEEELEELEEE-LEELEEELEELREELAELEAEL 462
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
666-1074 |
7.13e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 53.97 E-value: 7.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 666 QELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKdnEFTSIKHEKdaivcVQQEKDQKLLEMEKimhtq 745
Cdd:pfam17380 247 EDVTTMTPEYTVRYNGQTMTENEFLNQLLHIVQHQKAVSERQQQE--KFEKMEQER-----LRQEKEEKAREVER----- 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 746 HCEIKELKQSREMALEDLKKLHDE----------KIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKvmtdhnmsLEKL 815
Cdd:pfam17380 315 RRKLEEAEKARQAEMDRQAAIYAEqermamererELERIRQEERKRELERIRQEEIAMEISRMRELER--------LQME 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 816 KKENQQRIDQMLE-SHASTIQEKEQQLQELKLKVsdlsdmrcklevelalkeaETDEIKILLEESRTQQKEMLKSLLEQE 894
Cdd:pfam17380 387 RQQKNERVRQELEaARKVKILEEERQRKIQQQKV-------------------EMEQIRAEQEEARQREVRRLEEERARE 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 895 TENLRTEISKLNQKIhdnnesyqvglselralmtiekdqcisELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQI 974
Cdd:pfam17380 448 MERVRLEEQERQQQV---------------------------ERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKE 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 975 VELQTRlnselSALEKQKDEKITQQEekYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELV 1054
Cdd:pfam17380 501 LEERKQ-----AMIEEERKRKLLEKE--MEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMER 573
|
410 420
....*....|....*....|
gi 1907067116 1055 EKELLEKVKHLENQIAKTPA 1074
Cdd:pfam17380 574 EREMMRQIVESEKARAEYEA 593
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
679-1281 |
9.43e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.53 E-value: 9.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 679 LDALVKDSEENvNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIvcvqqekdQKLLEMEKIMHTQhceIKELKQSREM 758
Cdd:PRK03918 137 IDAILESDESR-EKVVRQILGLDDYENAYKNLGEVIKEIKRRIERL--------EKFIKRTENIEEL---IKEKEKELEE 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 759 ALEDLKKLHDEkIESLRAEFQCLEQNhLKELEDTLHIRHTQEFEKvmtdhnMSLEKLKKENQQRIDQMLEShastIQEKE 838
Cdd:PRK03918 205 VLREINEISSE-LPELREELEKLEKE-VKELEELKEEIEELEKEL------ESLEGSKRKLEEKIRELEER----IEELK 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 839 QQLQELKLKVSDLSDMRCKLEVELALKEaETDEIKilleeSRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNEsyqv 918
Cdd:PRK03918 273 KEIEELEEKVKELKELKEKAEEYIKLSE-FYEEYL-----DELREIEKRLSRLEEEINGIEERIKELEEKEERLEE---- 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 919 glselralmtiekdqcISELISRHEEESNILKA---ELDNVTSLHRQAYEIEKKLKEQIVElqtRLNSELSALEKQKdEK 995
Cdd:PRK03918 343 ----------------LKKKLKELEKRLEELEErheLYEEAKAKKEELERLKKRLTGLTPE---KLEKELEELEKAK-EE 402
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 996 ITQQEEKYEALIQNLEKDKERLVKN------------------HEQDKEHLIQELNFEKNKavqtaLDEFKVERELVEKE 1057
Cdd:PRK03918 403 IEEEISKITARIGELKKEIKELKKAieelkkakgkcpvcgrelTEEHRKELLEEYTAELKR-----IEKELKEIEEKERK 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1058 LLEKVKHLENQIAKTPAFESAREdssslVAELQEKLQEEKAKF-LEQLEeqekRKNEEMQNVRTSLI---AEQQTnfntv 1133
Cdd:PRK03918 478 LRKELRELEKVLKKESELIKLKE-----LAEQLKELEEKLKKYnLEELE----KKAEEYEKLKEKLIklkGEIKS----- 543
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1134 LTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRtSSFLSSAPVaaapelygacap 1213
Cdd:PRK03918 544 LKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFY-NEYLELKDA------------ 610
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907067116 1214 elPGEPERSVMETADEGR-LDSAMEtsMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLKRMEH 1281
Cdd:PRK03918 611 --EKELEREEKELKKLEEeLDKAFE--ELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSREL 675
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
832-1043 |
1.06e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 52.52 E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 832 STIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEmlkslLEQETENLRTEISKLNQKIHD 911
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDK-----LQAEIAEAEAEIEERREELGE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 912 NNESYQVGLSELRALMTIEKDQCISELISRheeesniLKAeLDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQ 991
Cdd:COG3883 91 RARALYRSGGSVSYLDVLLGSESFSDFLDR-------LSA-LSKIADADADLLEELKADKAELEAKKAELEAKLAELEAL 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907067116 992 KDEKITQQEE------KYEALIQNLEKDKERLvknhEQDKEHLIQELNFEKNKAVQTA 1043
Cdd:COG3883 163 KAELEAAKAEleaqqaEQEALLAQLSAEEAAA----EAQLAELEAELAAAEAAAAAAA 216
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
662-1173 |
1.18e-06 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 53.54 E-value: 1.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 662 EKHQQELQSLKIEYEcKLDALVKDSEENVNKILKLKENLVSLE-EALQNKDNEFTSIKHEKDAI-VCVQQEKDQKLLEME 739
Cdd:COG5022 878 ELAERQLQELKIDVK-SISSLKLVNLELESEIIELKKSLSSDLiENLEFKTELIARLKKLLNNIdLEEGPSIEYVKLPEL 956
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 740 KIMHTQHCEIKELKQSREMALEDLKKLHDEKI----ESLR-----AEFQCLE---QNHLKELEDTLHI--RHTQEFEKVM 805
Cdd:COG5022 957 NKLHEVESKLKETSEEYEDLLKKSTILVREGNkansELKNfkkelAELSKQYgalQESTKQLKELPVEvaELQSASKIIS 1036
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 806 TDHNmSLEKLKKENQQRIDQMLEshastIQEKEQQLQELKLKVSDLSDMRCKLE----VELALKEAETDEIKILLEESRT 881
Cdd:COG5022 1037 SEST-ELSILKPLQKLKGLLLLE-----NNQLQARYKALKLRRENSLLDDKQLYqlesTENLLKTINVKDLEVTNRNLVK 1110
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 882 QQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQC-------------ISELISRHE----- 943
Cdd:COG5022 1111 PANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEAnlealpspppfaaLSEKRLYQSalyde 1190
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 944 ------EESNILKAELDNVTSLHRQAYEIEKKLKEQIVE--LQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKE 1015
Cdd:COG5022 1191 ksklssSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEgwVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDN 1270
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1016 RLVKNHEQDKEH--------------LIQELNFEKNKAVQTALDEFKVEREL-----VEKELLEKVKHLENQIAKTPAFE 1076
Cdd:COG5022 1271 LLSSYKLEEEVLpatinsllqyinvgLFNALRTKASSLRWKSATEVNYNSEElddwcREFEISDVDEELEELIQAVKVLQ 1350
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1077 sAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKR-------KNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLS 1149
Cdd:COG5022 1351 -LLKDDLNKLDELLDACYSLNPAEIQNLKSRYDPadkennlPKEILKKIEALLIKQELQLSLEGKDETEVHLSEIFSEEK 1429
|
570 580
....*....|....*....|....*..
gi 1907067116 1150 DKL---KSTMQQQERDKDLIESLSEDR 1173
Cdd:COG5022 1430 SLIsldRNSIYKEEVLSSLSALLTKEK 1456
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
799-1165 |
2.53e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 52.43 E-value: 2.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 799 QEFEKVMTDHNMSLEKLkkenQQRIDQMLESHA-------STIQEKEQQLQELKLKVSDLSDMRcklevelaLKEAETDE 871
Cdd:pfam15921 74 EHIERVLEEYSHQVKDL----QRRLNESNELHEkqkfylrQSVIDLQTKLQEMQMERDAMADIR--------RRESQSQE 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 872 IKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHdnneSYQVGLSELRALMTiekdqciselisRHEEESNILKA 951
Cdd:pfam15921 142 DLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMML----SHEGVLQEIRSILV------------DFEEASGKKIY 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 952 ELDNVTSLHRQAY--EIEKKLKEQIVELqTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLI 1029
Cdd:pfam15921 206 EHDSMSTMHFRSLgsAISKILRELDTEI-SYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLT 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1030 qelnfEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAktpafesareDSSSLVAELQEKLQEEKAKFLEQLEEQEK 1109
Cdd:pfam15921 285 -----EKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLS----------DLESTVSQLRSELREAKRMYEDKIEELEK 349
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907067116 1110 R---KNEEMQNVRTS--LIAEQQTNFNTVLtrekmrkENIINDLSDKLKSTMQQQERDKDL 1165
Cdd:pfam15921 350 QlvlANSELTEARTErdQFSQESGNLDDQL-------QKLLADLHKREKELSLEKEQNKRL 403
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
769-1048 |
3.45e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.84 E-value: 3.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 769 EKIESLRAEFQCLEQnHLKELEDTLHIRHTQefEKVMTDHNMSLEKLKKENQQRIDqmLESHASTIQEKEQQLQELKLKV 848
Cdd:COG4913 610 AKLAALEAELAELEE-ELAEAEERLEALEAE--LDALQERREALQRLAEYSWDEID--VASAEREIAELEAELERLDASS 684
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 849 SDLSdmrcKLEVELALKEAETDEIKILLEESRTQQKEmlkslLEQETENLRTEISKLNQKIHDNNESYQVGLSElralmt 928
Cdd:COG4913 685 DDLA----ALEEQLEELEAELEELEEELDELKGEIGR-----LEKELEQAEEELDELQDRLEAAEDLARLELRA------ 749
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 929 iekdqcisELISRHEEesnilkAELDNVTSlhrqayEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQE-------- 1000
Cdd:COG4913 750 --------LLEERFAA------ALGDAVER------ELRENLEERIDALRARLNRAEEELERAMRAFNREWPaetadlda 809
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907067116 1001 -----EKYEALIQNLEKD---------KERLVKNHEQDKEHLIQELnfekNKAVQTALDEFK 1048
Cdd:COG4913 810 dleslPEYLALLDRLEEDglpeyeerfKELLNENSIEFVADLLSKL----RRAIREIKERID 867
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
876-1125 |
3.60e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.84 E-value: 3.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 876 LEESRTqqKEMLKSLLEQ--ETENLRTEISKLNQKIH------DNNESYQVGLSELRALmtiekDQCISEL-ISRHEEES 946
Cdd:COG4913 218 LEEPDT--FEAADALVEHfdDLERAHEALEDAREQIEllepirELAERYAAARERLAEL-----EYLRAALrLWFAQRRL 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 947 NILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNselsALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQdke 1026
Cdd:COG4913 291 ELLEAELEELRAELARLEAELERLEARLDALREELD----ELEAQIRGNGGDRLEQLEREIERLERELEERERRRAR--- 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1027 hliqelnfeknkaVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESA-REDSSSLVAELQEkLQEEKAKFLEQLE 1105
Cdd:COG4913 364 -------------LEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEAlEEALAEAEAALRD-LRRELRELEAEIA 429
|
250 260
....*....|....*....|...
gi 1907067116 1106 EQEKRKN---EEMQNVRTSLIAE 1125
Cdd:COG4913 430 SLERRKSnipARLLALRDALAEA 452
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
667-1104 |
6.80e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 50.81 E-value: 6.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 667 ELQSLKIE-YECKLDALVKDSEEnvnkilkLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQ 745
Cdd:PRK02224 303 GLDDADAEaVEARREELEDRDEE-------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEA 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 746 HCEIKElkqsREMALEDLkklhDEKIESLRAEFQCLE------QNHLKELEDTLHIRHTQEFEKVMTDHNmsLEKLKKEN 819
Cdd:PRK02224 376 REAVED----RREEIEEL----EEEIEELRERFGDAPvdlgnaEDFLEELREERDELREREAELEATLRT--ARERVEEA 445
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 820 QQRID--------QMLE--SHASTIQEKEQQLQELKLKVSDLSDMRCKLEVEL----ALKEAET-----DEIKILLEESR 880
Cdd:PRK02224 446 EALLEagkcpecgQPVEgsPHVETIEEDRERVEELEAELEDLEEEVEEVEERLeraeDLVEAEDrierlEERREDLEELI 525
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 881 TQQKEMLKSLLEQeTENLRTEISKLNQKIHDNNESYQVGLSELRalmtiEKDQCISELISRHEEesniLKAELDNVTSLH 960
Cdd:PRK02224 526 AERRETIEEKRER-AEELRERAAELEAEAEEKREAAAEAEEEAE-----EAREEVAELNSKLAE----LKERIESLERIR 595
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 961 RQAYEIEkKLKEQIVELQTRLnSELSALEKQ-------KDEKITQQEEKY-EALIQNLEKDKERLVKNHEQDKEHLiQEL 1032
Cdd:PRK02224 596 TLLAAIA-DAEDEIERLREKR-EALAELNDErrerlaeKRERKRELEAEFdEARIEEAREDKERAEEYLEQVEEKL-DEL 672
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907067116 1033 NfEKNKAVQTALDefKVERELVE-KELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQL 1104
Cdd:PRK02224 673 R-EERDDLQAEIG--AVENELEElEELRERREALENRVEALEALYDEAEELESMYGDLRAELRQRNVETLERM 742
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
682-1175 |
6.85e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.99 E-value: 6.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 682 LVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHceiKELKQSREMALE 761
Cdd:pfam12128 232 AIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLD---DQWKEKRDELNG 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 762 DLKKLhDEKIESLRAEFQCLEQNHLKELEDTLHIRHtQEFEkvmtdhNMSLEKLKKENQQRIDQMLESHASTIQEKeqqL 841
Cdd:pfam12128 309 ELSAA-DAAVAKDRSELEALEDQHGAFLDADIETAA-ADQE------QLPSWQSELENLEERLKALTGKHQDVTAK---Y 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 842 QELKLKVSDlsdmrcKLEVELALKEAETDEIKilleESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLS 921
Cdd:pfam12128 378 NRRRSKIKE------QNNRDIAGIKDKLAKIR----EARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLG 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 922 ELRALM--------TIEKDQCISELISRHEEESNILKAELDNVTSLHRQAyeieKKLKEQIVELQTRLNSELSALEKQKD 993
Cdd:pfam12128 448 ELKLRLnqatatpeLLLQLENFDERIERAREEQEAANAEVERLQSELRQA----RKRRDQASEALRQASRRLEERQSALD 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 994 EKITQQEEKYEALIQNLEKD----KERLVK------------NHEQDKEHLIQELNF----------------------- 1034
Cdd:pfam12128 524 ELELQLFPQAGTLLHFLRKEapdwEQSIGKvispellhrtdlDPEVWDGSVGGELNLygvkldlkridvpewaaseeelr 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1035 EKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTP----AFESAREDSSSLVAELQEklqeEKAKFLEQLEEQEKR 1110
Cdd:pfam12128 604 ERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETfartALKNARLDLRRLFDEKQS----EKDKKNKALAERKDS 679
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907067116 1111 KNEEmqnvRTSLIAEQQTNFNTVLTREKMRKEniindlsDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:pfam12128 680 ANER----LNSLEAQLKQLDKKHQAWLEEQKE-------QKREARTEKQAYWQVVEGALDAQLAL 733
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
828-1131 |
7.67e-06 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 50.62 E-value: 7.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 828 ESHASTIQEKEQQLQELKLKVSDLSDMRCKLeVELALKEAetdeIKILLEESRTQQKEMLKSL-LEQETENLRTEISKLN 906
Cdd:PLN03229 425 EAVKTPVRELEGEVEKLKEQILKAKESSSKP-SELALNEM----IEKLKKEIDLEYTEAVIAMgLQERLENLREEFSKAN 499
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 907 -----------QKIHDNNESYQVGLSE----------LRALMTIEKDQCISELISRHE--------------------EE 945
Cdd:PLN03229 500 sqdqlmhpvlmEKIEKLKDEFNKRLSRapnylslkykLDMLNEFSRAKALSEKKSKAEklkaeinkkfkevmdrpeikEK 579
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 946 SNILKAELDNvtSLHRQAYEIEKKLKEQIVELQTRLNSELSALEK---------QKDEKITQQEEKYEALIQNLEKDKER 1016
Cdd:PLN03229 580 MEALKAEVAS--SGASSGDELDDDLKEKVEKMKKEIELELAGVLKsmglevigvTKKNKDTAEQTPPPNLQEKIESLNEE 657
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1017 LVKNHEQ-----DKEHLIQELNFEKNKAVQTALDEFKverelvekellEKVKHLENQIAKTPAfesAREDSSSLvAELQE 1091
Cdd:PLN03229 658 INKKIERvirssDLKSKIELLKLEVAKASKTPDVTEK-----------EKIEALEQQIKQKIA---EALNSSEL-KEKFE 722
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1907067116 1092 KLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFN 1131
Cdd:PLN03229 723 ELEAELAAARETAAESNGSLKNDDDKEEDSKEDGSRVEVN 762
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
681-909 |
8.80e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 8.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 681 ALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMAL 760
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 761 EDLKKLHDEKIESLRAEFQCLEQNHLKELedtLHIRHTQEFEKVMtdhnMSLEKLKKENQQRIDQMleshASTIQEKEQQ 840
Cdd:COG4942 97 AELEAQKEELAELLRALYRLGRQPPLALL---LSPEDFLDAVRRL----QYLKYLAPARREQAEEL----RADLAELAAL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907067116 841 LQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSL--LEQETENLRTEISKLNQKI 909
Cdd:COG4942 166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELaeLQQEAEELEALIARLEAEA 236
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
728-1110 |
8.95e-06 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 49.89 E-value: 8.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 728 QQEKDQKLLEMEKIMHTQHCEIKELKQSREmALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTlhiRHTQEFEKVMTD 807
Cdd:pfam07888 40 LQERAELLQAQEAANRQREKEKERYKRDRE-QWERQRRELESRVAELKEELRQSREKHEELEEKY---KELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 808 HNMSLEKLKKENQQRIDQMLESHASTIQ---EKEQQLQELKLKVSDLSDMRCKLEVElalKEAETDEIKILLEESRTQQK 884
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEDIKTLTQrvlERETELERMKERAKKAGAQRKEEEAE---RKQLQAKLQQTEEELRSLSK 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 885 EM--LKSLLEQ---ETENLRTEISKLNQKI---HDNNESYQVGLSELRALmtiekdqciSELISRHEEESNILKAELDNV 956
Cdd:pfam07888 193 EFqeLRNSLAQrdtQVLQLQDTITTLTQKLttaHRKEAENEALLEELRSL---------QERLNASERKVEGLGEELSSM 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 957 TSLHRQAYEIEKKLKEQIVELQTRLNSELSALekqKDEKITQQEEKyEALIQNLEKDKERlvknheqdkehlIQELNFEK 1036
Cdd:pfam07888 264 AAQRDRTQAELHQARLQAAQLTLQLADASLAL---REGRARWAQER-ETLQQSAEADKDR------------IEKLSAEL 327
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907067116 1037 NKAvQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKR 1110
Cdd:pfam07888 328 QRL-EERLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQR 400
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
749-1175 |
9.00e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 50.42 E-value: 9.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 749 IKELKQSREMALEDLKKLHDEKIE-SLRAEFQCLEQNhLKELEDTLHIRHTQ---------EFEKVMTDHNMSLEKLKkE 818
Cdd:PRK02224 178 VERVLSDQRGSLDQLKAQIEEKEEkDLHERLNGLESE-LAELDEEIERYEEQreqaretrdEADEVLEEHEERREELE-T 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 819 NQQRIDQMLESHASTIQEKE---QQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQ-- 893
Cdd:PRK02224 256 LEAEIEDLRETIAETEREREelaEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECrv 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 894 -------ETENLRTEISKL---NQKIHDNNESYQVGLSELRALMTIEKDQcISEL---ISRHEEESNILKAELDNVTSLH 960
Cdd:PRK02224 336 aaqahneEAESLREDADDLeerAEELREEAAELESELEEAREAVEDRREE-IEELeeeIEELRERFGDAPVDLGNAEDFL 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 961 RQAYEIEKKLKEQIVELQTRLNSELSALEKQKD-----------------------EKITQQEEKYEALIQNLEKDKERL 1017
Cdd:PRK02224 415 EELREERDELREREAELEATLRTARERVEEAEAlleagkcpecgqpvegsphvetiEEDRERVEELEAELEDLEEEVEEV 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1018 VKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEK 1097
Cdd:PRK02224 495 EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEV 574
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1098 AKFLEQLEEQEKRKnEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLS-DKLKStmqQQERDKDL--------IES 1168
Cdd:PRK02224 575 AELNSKLAELKERI-ESLERIRTLLAAIADAEDEIERLREKREALAELNDERrERLAE---KRERKRELeaefdearIEE 650
|
....*..
gi 1907067116 1169 LSEDRAR 1175
Cdd:PRK02224 651 AREDKER 657
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
654-1018 |
9.47e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.45 E-value: 9.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 654 CSLEITlkEKHQQELQSlkiEYECKLDALVKDSEENVNKILKLKENLVSLEEALqnkdneftsikhekdaivcvqqEKDQ 733
Cdd:PRK03918 441 CGRELT--EEHRKELLE---EYTAELKRIEKELKEIEEKERKLRKELRELEKVL----------------------KKES 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 734 KLLEMEKIMHtqhcEIKELKQS-REMALEDLKKlHDEKIESLRAEFQCLEQNhLKELEDTLhiRHTQEFEKVMTDHNMSL 812
Cdd:PRK03918 494 ELIKLKELAE----QLKELEEKlKKYNLEELEK-KAEEYEKLKEKLIKLKGE-IKSLKKEL--EKLEELKKKLAELEKKL 565
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 813 EKLKKENQQRIDQMLESHASTIQEKEQQLQELK--------LKVS-----DLSDMRCKLEVELALKEAETDEIKILLEES 879
Cdd:PRK03918 566 DELEEELAELLKELEELGFESVEELEERLKELEpfyneyleLKDAekeleREEKELKKLEEELDKAFEELAETEKRLEEL 645
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 880 RTQQKEMLKSLLEQETENLRTEISKLNQKIhdnnESYQVGLSELRALM-----TIEKDQCISELISRHEEESNILKAELD 954
Cdd:PRK03918 646 RKELEELEKKYSEEEYEELREEYLELSREL----AGLRAELEELEKRReeikkTLEKLKEELEEREKAKKELEKLEKALE 721
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907067116 955 NVTslhrqayEIEKKLKEQIVELQTRLNSELSALEKQKDEKITqqEEKYEALIQNLEKDKERLV 1018
Cdd:PRK03918 722 RVE-------ELREKVKKYKALLKERALSKVGEIASEIFEELT--EGKYSGVRVKAEENKVKLF 776
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
812-1175 |
1.36e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 812 LEKLKKENQQRIDQMLESHAST--IQEKEQQLQELKLKVSDLSDMRCKLEVELALKE--AETDEIKILLEESRTQQKEML 887
Cdd:COG4717 73 LKELEEELKEAEEKEEEYAELQeeLEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEELE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 888 KSLleQETENLRTEISKLNQKIHDNNESyqvgLSELRALMTIEKDQCISELISRHEEesniLKAELdnvtslhRQAYEIE 967
Cdd:COG4717 153 ERL--EELRELEEELEELEAELAELQEE----LEELLEQLSLATEEELQDLAEELEE----LQQRL-------AELEEEL 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 968 KKLKEQIVELQTRLNSELSALEKQKD-EKITQQEEKYEAL--------------------------------IQNLEKDK 1014
Cdd:COG4717 216 EEAQEELEELEEELEQLENELEAAALeERLKEARLLLLIAaallallglggsllsliltiagvlflvlgllaLLFLLLAR 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1015 ERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDS--SSLVAELQEK 1092
Cdd:COG4717 296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqlEELEQEIAAL 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1093 LQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIiNDLSDKLKSTMQQQERDKDLIESLSED 1172
Cdd:COG4717 376 LAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEELREE 454
|
...
gi 1907067116 1173 RAR 1175
Cdd:COG4717 455 LAE 457
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
864-1199 |
1.59e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.58 E-value: 1.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 864 LKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMtiEKDQCISELISRHE 943
Cdd:pfam02463 159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELE--EEYLLYLDYLKLNE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 944 EESNILKAELdNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQ 1023
Cdd:pfam02463 237 ERIDLLQELL-RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEK 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1024 DKEHLIQELNFEKN-KAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLE 1102
Cdd:pfam02463 316 LKESEKEKKKAEKElKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1103 QLEEQEKRKNE--------EMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRA 1174
Cdd:pfam02463 396 ELELKSEEEKEaqlllelaRQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLK 475
|
330 340
....*....|....*....|....*
gi 1907067116 1175 RLLEEKKQLEEEVSKLRTSSFLSSA 1199
Cdd:pfam02463 476 ETQLVKLQEQLELLLSRQKLEERSQ 500
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
649-1172 |
2.00e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.37 E-value: 2.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 649 IEKVKCSLEITLKEKHQQELQSLKIEYEckldalVKDSEENVNKILKLKENLVSLEEAlqNKDNEFTSIKHEKDAIVCVQ 728
Cdd:PTZ00121 1226 AEAVKKAEEAKKDAEEAKKAEEERNNEE------IRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADEAKK 1297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 729 QEKDQKLLEMEKIMHTQHcEIKELKQSREMA---LEDLKKLHDEKIESLRAEfQCLEQNHLKELEDTLHIRHTQEFEKVM 805
Cdd:PTZ00121 1298 AEEKKKADEAKKKAEEAK-KADEAKKKAEEAkkkADAAKKKAEEAKKAAEAA-KAEAEAAADEAEAAEEKAEAAEKKKEE 1375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 806 TDHNMSLEKLKKENQQRIDQmLESHASTIQEKEQQLQELKLKVSDLSDMRCKLE----VELALKEAE----TDEIKILLE 877
Cdd:PTZ00121 1376 AKKKADAAKKKAEEKKKADE-AKKKAEEDKKKADELKKAAAAKKKADEAKKKAEekkkADEAKKKAEeakkADEAKKKAE 1454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 878 ESRTQQKEMLKSLLEQETENLR--TEISKLNQKIHDNNESYQVGLSELRALMTIEKDqciSELISRHEEESnilKAELDN 955
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK---ADEAKKAEEAK---KADEAK 1528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 956 VTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEE-------KYEALIQNLEKDKERLVKNHEQDKEHL 1028
Cdd:PTZ00121 1529 KAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEdknmalrKAEEAKKAEEARIEEVMKLYEEEKKMK 1608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1029 IQELNFEKNKAVQTalDEFKVERElVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQE 1108
Cdd:PTZ00121 1609 AEEAKKAEEAKIKA--EELKKAEE-EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907067116 1109 KRKNEEMQNVRTSLIAEQQTNFNTVLTREK-----MRKENIINDLsdKLKSTMQQQERDKDLIESLSED 1172
Cdd:PTZ00121 1686 DEKKAAEALKKEAEEAKKAEELKKKEAEEKkkaeeLKKAEEENKI--KAEEAKKEAEEDKKKAEEAKKD 1752
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
878-1128 |
2.45e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.29 E-value: 2.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 878 ESRTQQKEMLKSLLEQETENLRTEISKLNQKIHDNNESYQVGLSELRALmtiekdqciselisrhEEESNILKAELDNVT 957
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEAL----------------QAEIDKLQAEIAEAE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 958 SLHRQAYEiekKLKEQIVELQT--RLNSELSALEKQKD--------EKITQQEEKYEALIQNLEKDKERLvknheqdkeh 1027
Cdd:COG3883 79 AEIEERRE---ELGERARALYRsgGSVSYLDVLLGSESfsdfldrlSALSKIADADADLLEELKADKAEL---------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1028 liqelnfeknKAVQTALDEFKVERELVEKELLEKVKHLENQIAKtpafesaREDSSSLVAELQEKLQEEKAKFLEQLEEQ 1107
Cdd:COG3883 146 ----------EAKKAELEAKLAELEALKAELEAAKAELEAQQAE-------QEALLAQLSAEEAAAEAQLAELEAELAAA 208
|
250 260
....*....|....*....|.
gi 1907067116 1108 EKRKNEEMQNVRTSLIAEQQT 1128
Cdd:COG3883 209 EAAAAAAAAAAAAAAAAAAAA 229
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
661-1280 |
2.99e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.98 E-value: 2.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 661 KEKHQQELQSLKIEYECKLDALVKDSEEnVNKILKLK--ENLVSLEEALQNKDNEFTSIKHEKDAivCVQQEKDQKLLEM 738
Cdd:PTZ00121 1099 KAEEAKKTETGKAEEARKAEEAKKKAED-ARKAEEARkaEDARKAEEARKAEDAKRVEIARKAED--ARKAEEARKAEDA 1175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 739 EKIMHTQHCEikELKQSREmaledLKKLHD-EKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEKLKK 817
Cdd:PTZ00121 1176 KKAEAARKAE--EVRKAEE-----LRKAEDaRKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEE 1248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 818 ENQQRIDQMLESHASTIQEKEQQLQ-ELKLKVSDLSDMRCKLEVELALKEAE---TDEIKILLEESRTQQKemlkslLEQ 893
Cdd:PTZ00121 1249 RNNEEIRKFEEARMAHFARRQAAIKaEEARKADELKKAEEKKKADEAKKAEEkkkADEAKKKAEEAKKADE------AKK 1322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 894 ETENLRTEISKLNQKIHDNNESYQVGLSELRALM-TIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKE 972
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAdEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE 1402
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 973 QivelqtrlnselsalEKQKDEKITQQEEKYEAliQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERE 1052
Cdd:PTZ00121 1403 D---------------KKKADELKKAAAAKKKA--DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1053 LVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKlQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNT 1132
Cdd:PTZ00121 1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKA-AEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE 1544
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1133 VLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARllEEKKQLEEEVSKLRTSSFLSSAPVAAAPELYGACA 1212
Cdd:PTZ00121 1545 KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK--KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907067116 1213 PELPGEPErsvmETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLErtLQLKEEENKRLNQRLKRME 1280
Cdd:PTZ00121 1623 EELKKAEE----EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE--EAKKAEEDKKKAEEAKKAE 1684
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
981-1295 |
3.39e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 48.58 E-value: 3.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 981 LNSELSALEKQKDEKITQQEEKYEALIQnlekdkERLvknhEQDKEHLIQELNF-----EKNKAVQTALDEFKVERELVE 1055
Cdd:pfam17380 271 LNQLLHIVQHQKAVSERQQQEKFEKMEQ------ERL----RQEKEEKAREVERrrkleEAEKARQAEMDRQAAIYAEQE 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1056 KELLEKVKHLENQIAKTPAFESAREDSSSLVAELqeklqeEKAKFLEQLEEQEKRKNEEmqnVRTSLIAEQQTNFntvlt 1135
Cdd:pfam17380 341 RMAMERERELERIRQEERKRELERIRQEEIAMEI------SRMRELERLQMERQQKNER---VRQELEAARKVKI----- 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1136 REKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARL----LEEKKQLEEEVSKLRTSSF----------LSSAPV 1201
Cdd:pfam17380 407 LEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREmervRLEEQERQQQVERLRQQEEerkrkkleleKEKRDR 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1202 AAAPELYGACAPELPGEPERSVMEtadEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLKRMEH 1281
Cdd:pfam17380 487 KRAEEQRRKILEKELEERKQAMIE---EERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATE 563
|
330
....*....|....
gi 1907067116 1282 VCHHSVSMDSEDKM 1295
Cdd:pfam17380 564 ERSRLEAMEREREM 577
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
785-1146 |
3.57e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 48.51 E-value: 3.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 785 HLKELEDTLHIRHTQEFEKVMTDHNMSLE---KLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVE 861
Cdd:TIGR01612 501 RMKDFKDIIDFMELYKPDEVPSKNIIGFDidqNIKAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKE 580
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 862 ---LALKEAETDEIKILLEESRTQQKEMLKSLLEQeTENLRTEISKlnQKIHDNNESYQVGLSELRALMTIE----KDQC 934
Cdd:TIGR01612 581 ikdLFDKYLEIDDEIIYINKLKLELKEKIKNISDK-NEYIKKAIDL--KKIIENNNAYIDELAKISPYQVPEhlknKDKI 657
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 935 ISELISrheEESNILKAELDnvtSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDK 1014
Cdd:TIGR01612 658 YSTIKS---ELSKIYEDDID---ALYNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKK 731
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1015 ERLVKNHEQDKEHLIQELNFEKNKAVQtaldEFKVErelvEKELLEKVKHLENQIAKTPAFESAredssslVAELQEKLQ 1094
Cdd:TIGR01612 732 NELLDIIVEIKKHIHGEINKDLNKILE----DFKNK----EKELSNKINDYAKEKDELNKYKSK-------ISEIKNHYN 796
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1907067116 1095 EEKAkfLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIIN 1146
Cdd:TIGR01612 797 DQIN--IDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLN 846
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
656-1071 |
3.67e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.39 E-value: 3.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 656 LEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIvcvqQEKDQKL 735
Cdd:COG1196 358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL----EEALAEL 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 736 LEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKVMTDHNMS-LEK 814
Cdd:COG1196 434 EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvKAA 513
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 815 LKKENQQRIDQMLESHASTIQEKEQQLQE------LKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLK 888
Cdd:COG1196 514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAalaaalQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALA 593
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 889 SLLEQETENLRTEisklnQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEK 968
Cdd:COG1196 594 RGAIGAAVDLVAS-----DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 969 KLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDK-------EHLIQELNFEKNKAVQ 1041
Cdd:COG1196 669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAleeqleaEREELLEELLEEEELL 748
|
410 420 430
....*....|....*....|....*....|
gi 1907067116 1042 TALDEFKVERELVEKELLEKVKHLENQIAK 1071
Cdd:COG1196 749 EEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
879-1175 |
5.10e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 47.81 E-value: 5.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 879 SRTQQKE----MLKSLLEQETENLRTEISKlNQKIHDNNESYQVGLSELRALMtiekdqciseliSRHEEESNILKAELD 954
Cdd:pfam17380 285 SERQQQEkfekMEQERLRQEKEEKAREVER-RRKLEEAEKARQAEMDRQAAIY------------AEQERMAMERERELE 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 955 NVTSLHRQAyEIEKKLKEQI-VELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELN 1033
Cdd:pfam17380 352 RIRQEERKR-ELERIRQEEIaMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQE 430
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1034 FEKNKAVQTALDEFKVERELVEKELLEKVKHLEnQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNE 1113
Cdd:pfam17380 431 EARQREVRRLEEERAREMERVRLEEQERQQQVE-RLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMI 509
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907067116 1114 EMQNVRTSLIAEQQTNFNTVLTREKMRKEniinDLSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:pfam17380 510 EEERKRKLLEKEMEERQKAIYEEERRREA----EEERRKQQEMEERRRIQEQMRKATEERSR 567
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
924-1063 |
5.68e-05 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 47.90 E-value: 5.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 924 RALMTIEKDQcISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKY 1003
Cdd:PRK00409 508 KKLIGEDKEK-LNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEA 586
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907067116 1004 EALIQNLekdKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVERELVEK-ELLEKVK 1063
Cdd:PRK00409 587 DEIIKEL---RQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEElKVGDEVK 644
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
695-1173 |
6.63e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.51 E-value: 6.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 695 KLKENLVSLEEalQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDlkklHDEKIESL 774
Cdd:pfam10174 204 KEKENIHLREE--LHRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTED----REEEIKQM 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 775 RA--EFQCLEQNHLKELEDTLHIRHTQefekvMTDHNMSLEKLKKEN---QQRIDQMLESHAStiqeKEQQLQELKLKVS 849
Cdd:pfam10174 278 EVykSHSKFMKNKIDQLKQELSKKESE-----LLALQTKLETLTNQNsdcKQHIEVLKESLTA----KEQRAAILQTEVD 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 850 DLsdmRCKLEVELALKEAETDEIKILLEESRTQQKEM--LKSLL---EQETENLRTEISKLNQKIHDNNESyqvgLSELR 924
Cdd:pfam10174 349 AL---RLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIrdLKDMLdvkERKINVLQKKIENLQEQLRDKDKQ----LAGLK 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 925 ---------------ALMTIE-----KDQCISELISRHEEESnilKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSE 984
Cdd:pfam10174 422 ervkslqtdssntdtALTTLEealseKERIIERLKEQRERED---RERLEELESLKKENKDLKEKVSALQPELTEKESSL 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 985 LSALEK---------QKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKE------------HLIQELNFEKNKAVQTA 1043
Cdd:pfam10174 499 IDLKEHasslassglKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAvrtnpeindrirLLEQEVARYKEESGKAQ 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1044 LDefkVERELVEKELLEKVKHLENQiaKTPAFESAR----EDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVR 1119
Cdd:pfam10174 579 AE---VERLLGILREVENEKNDKDK--KIAELESLTlrqmKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQ 653
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 1907067116 1120 TSLIAEqqtnfnTVLTREKMRKEniINDLSDKLKSTMQQ-QERDKDLiESLSEDR 1173
Cdd:pfam10174 654 QLQLEE------LMGALEKTRQE--LDATKARLSSTQQSlAEKDGHL-TNLRAER 699
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
656-1023 |
6.87e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 47.59 E-value: 6.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 656 LEITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEftsikhekdaivcvQQEKDQKL 735
Cdd:PLN02939 65 LQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDG--------------EQLSDFQL 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 736 LEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKiESLRAEFQCLEQNhlkeLEDTLHIRHTQEFEKVMTDHNMS-LEK 814
Cdd:PLN02939 131 EDLVGMIQNAEKNILLLNQARLQALEDLEKILTEK-EALQGKINILEMR----LSETDARIKLAAQEKIHVEILEEqLEK 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 815 LKKENQQRIdqmlESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELaLKEAETDEIKILLEESRTQQKEMLKSlLEQE 894
Cdd:PLN02939 206 LRNELLIRG----ATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAEL-IEVAETEERVFKLEKERSLLDASLRE-LESK 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 895 TENLRTEISKlnqkihdnnesyqvgLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQI 974
Cdd:PLN02939 280 FIVAQEDVSK---------------LSPLQYDCWWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEAN 344
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 975 VelqTRLNSELSALEKQK-----------DEKITQQEEKYEALIQNLEKDKERLVKNHEQ 1023
Cdd:PLN02939 345 V---SKFSSYKVELLQQKlklleerlqasDHEIHSYIQLYQESIKEFQDTLSKLKEESKK 401
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
728-1172 |
1.66e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.12 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 728 QQEKDQKLLEMEKIMHTQHCEIKELKQSREMALE--DLKKLHDEKIESLRAEFQCLEQnhlkeledtlhirHTQEFEKVM 805
Cdd:TIGR00618 151 QGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMefAKKKSLHGKAELLTLRSQLLTL-------------CTPCMPDTY 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 806 TDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKvSDLSDMRCKLEvELALKEAETDEikilLEESRTQQKE 885
Cdd:TIGR00618 218 HERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQ-QLLKQLRARIE-ELRAQEAVLEE----TQERINRARK 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 886 MLKSLLEQE-TENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDNVTSLHRQAY 964
Cdd:TIGR00618 292 AAPLAAHIKaVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREIS 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 965 EIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTAL 1044
Cdd:TIGR00618 372 CQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTA 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1045 DEFKVeRELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAkfleQLEEQEKRKNEEMQNvrtSLIA 1124
Cdd:TIGR00618 452 QCEKL-EKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPC----PLCGSCIHPNPARQD---IDNP 523
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1907067116 1125 EQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSED 1172
Cdd:TIGR00618 524 GPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQS 571
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
827-1109 |
1.94e-04 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 45.44 E-value: 1.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 827 LESHASTIQE----KEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKilLEESRTQQKEMLKSLLEQETENLRTEI 902
Cdd:pfam15742 46 LKQHNSLLQEenikIKAELKQAQQKLLDSTKMCSSLTAEWKHCQQKIRELE--LEVLKQAQSIKSQNSLQEKLAQEKSRV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 903 SKLNQKIHDN----NESYQVGLSELRALMT-------IEKDQCISELISRHEEESNILKAELDNVTSLHRQA---YEIEK 968
Cdd:pfam15742 124 ADAEEKILELqqklEHAHKVCLTDTCILEKkqleeriKEASENEAKLKQQYQEEQQKRKLLDQNVNELQQQVrslQDKEA 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 969 KLKEQIVELQTRLNSELSALEKQKDEKITQQEE-----KYEALIQNLEKDKERLVKNHEQDKEHLIQEL-------NFEK 1036
Cdd:pfam15742 204 QLEMTNSQQQLRIQQQEAQLKQLENEKRKSDEHlksnqELSEKLSSLQQEKEALQEELQQVLKQLDVHVrkynekhHHHK 283
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907067116 1037 NKaVQTALDEFKVERELVEkellEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEK 1109
Cdd:pfam15742 284 AK-LRRAKDRLVHEVEQRD----ERIKQLENEIGILQQQSEKEKAFQKQVTAQNEILLLEKRKLLEQLTEQEE 351
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
966-1280 |
2.06e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 966 IEKKLKEQIVELQT-------RLNSELSALEKQKDEkITQQEEKYEALIQNLEKDKERLvKNHEQDKEHLIQELNF-EKN 1037
Cdd:COG4717 47 LLERLEKEADELFKpqgrkpeLNLKELKELEEELKE-AEEKEEEYAELQEELEELEEEL-EELEAELEELREELEKlEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1038 KAVQTALDEFK-VERELveKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQ 1116
Cdd:COG4717 125 LQLLPLYQELEaLEAEL--AELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1117 NVRTSlIAEQQTNFNTvLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKLRTSSFL 1196
Cdd:COG4717 203 ELQQR-LAELEEELEE-AQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLF 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1197 SSAPVAAAPELYGACAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEENKRLNQRL 1276
Cdd:COG4717 281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360
|
....
gi 1907067116 1277 KRME 1280
Cdd:COG4717 361 EELQ 364
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
959-1113 |
2.18e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.53 E-value: 2.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 959 LHRQAYEIEKKLKE---QIVELQTRLNSELSALEKQKDEKitqqeEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFE 1035
Cdd:COG1579 15 LDSELDRLEHRLKElpaELAELEDELAALEARLEAAKTEL-----EDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNK 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907067116 1036 KNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNE 1113
Cdd:COG1579 90 EYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREE 167
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
795-1019 |
2.46e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 45.39 E-value: 2.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 795 IRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSdmRCKLEVELALKEAETDEIKI 874
Cdd:PHA02562 190 IDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLV--MDIEDPSAALNKLNTAAAKI 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 875 lleESRTQQKEMLKSLLEQE------TENLRTEISKLnQKIHDNNESYQVGLSELralmtiekDQCISELISRHEEESNI 948
Cdd:PHA02562 268 ---KSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRI-TKIKDKLKELQHSLEKL--------DTAIDELEEIMDEFNEQ 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 949 LKA--ELDNVTSLHRQAYEIE----KKLKEQIVELQ---TRLNSELSALEKQKDEKITQQ----EEKYE-ALIQNLEKD- 1013
Cdd:PHA02562 336 SKKllELKNKISTNKQSLITLvdkaKKVKAAIEELQaefVDNAEELAKLQDELDKIVKTKselvKEKYHrGIVTDLLKDs 415
|
....*...
gi 1907067116 1014 --KERLVK 1019
Cdd:PHA02562 416 giKASIIK 423
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
704-1274 |
2.54e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 45.55 E-value: 2.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 704 EEALQNKDNEFTSIKHekdaivcVQQEKDQKLLEMEKiMHTQHCEIKELKQSREMALEDLKKlhdeKIESLRAEFQCLEQ 783
Cdd:pfam01576 4 EEEMQAKEEELQKVKE-------RQQKAESELKELEK-KHQQLCEEKNALQEQLQAETELCA----EAEEMRARLAARKQ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 784 nhlkELEDTLHIRHTQEFEKvmTDHNMSLEKLKKENQQRIdQMLESHastIQEKEQQLQELKLKvsdlsdmrcKLEVELA 863
Cdd:pfam01576 72 ----ELEEILHELESRLEEE--EERSQQLQNEKKKMQQHI-QDLEEQ---LDEEEAARQKLQLE---------KVTTEAK 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 864 LKEAEtDEIKILLEESRTQQKEmlKSLLEQETENLRT------EISKLNQKIHDNNEsyqvglselrALMTIEKDQCISE 937
Cdd:pfam01576 133 IKKLE-EDILLLEDQNSKLSKE--RKLLEERISEFTSnlaeeeEKAKSLSKLKNKHE----------AMISDLEERLKKE 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 938 LISRHEEESNILKAELDNVTslhrqayeiekkLKEQIVELQTRLnSELSAlekqkdeKITQQEEKYEALIQNLEKdkERL 1017
Cdd:pfam01576 200 EKGRQELEKAKRKLEGESTD------------LQEQIAELQAQI-AELRA-------QLAKKEEELQAALARLEE--ETA 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1018 VKNHEQDKEHLIQELNFEknkaVQTALDEFKVERELVEK------ELLEKVK-HLENQIAKTPAFESAREDSSSLVAELQ 1090
Cdd:pfam01576 258 QKNNALKKIRELEAQISE----LQEDLESERAARNKAEKqrrdlgEELEALKtELEDTLDTTAAQQELRSKREQEVTELK 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1091 EKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLiaEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQ----QQERDKDLI 1166
Cdd:pfam01576 334 KALEEETRSHEAQLQEMRQKHTQALEELTEQL--EQAKRNKANLEKAKQALESENAELQAELRTLQQakqdSEHKRKKLE 411
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1167 ESLSEDRARLLEEKKQLEEEVSKLrtssflssapVAAAPELYGACApeLPGEPERSVMETADEGrldSAMETSMMSVQEN 1246
Cdd:pfam01576 412 GQLQELQARLSESERQRAELAEKL----------SKLQSELESVSS--LLNEAEGKNIKLSKDV---SSLESQLQDTQEL 476
|
570 580
....*....|....*....|....*...
gi 1907067116 1247 MLSEEKQRIMLLERTLQLKEEENKRLNQ 1274
Cdd:pfam01576 477 LQEETRQKLNLSTRLRQLEDERNSLQEQ 504
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
660-1012 |
2.81e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.40 E-value: 2.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 660 LKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEME 739
Cdd:TIGR04523 423 LLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLN 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 740 KIMHTQHCEIKELKQSREMALEDLKKLHDEKIEslraefqclEQNHLKELEDtlhirhtqEFEKVMTDHNMS-LEKLKKE 818
Cdd:TIGR04523 503 EEKKELEEKVKDLTKKISSLKEKIEKLESEKKE---------KESKISDLED--------ELNKDDFELKKEnLEKEIDE 565
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 819 NQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTqqkemlkslLEQETENL 898
Cdd:TIGR04523 566 KNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEK---------LSSIIKNI 636
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 899 RTEISKLNQKIhdnnESYQVGLSELRALMTiEKDQCISELISRHEEESNILKaELDNVTSLHRQAY---EIEKKLKEQIV 975
Cdd:TIGR04523 637 KSKKNKLKQEV----KQIKETIKEIRNKWP-EIIKKIKESKTKIDDIIELMK-DWLKELSLHYKKYitrMIRIKDLPKLE 710
|
330 340 350
....*....|....*....|....*....|....*..
gi 1907067116 976 ELQTRLNSELSALEKQKDEkitqqeekYEALIQNLEK 1012
Cdd:TIGR04523 711 EKYKEIEKELKKLDEFSKE--------LENIIKNFNK 739
|
|
| CCDC73 |
pfam15818 |
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ... |
812-1145 |
2.93e-04 |
|
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.
Pssm-ID: 464893 [Multi-domain] Cd Length: 1048 Bit Score: 45.32 E-value: 2.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 812 LEKLKKENQQRIDQMLESHASTIQEKEQQLQelkLKVSDLSDMRCKLEVELALKEAETDEIKilleesrtqqkEMLKSLl 891
Cdd:pfam15818 40 LKWQKETLQNQKETLAKQHKEAMAVFKKQLQ---MKMCALEEEKGKYQLATEIKEKEIEGLK-----------ETLKAL- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 892 EQETENLRTEISKLNQKIHDN---NESYQVGLSELR---ALMT--------------------IEKDQCISELISRHEEE 945
Cdd:pfam15818 105 QVSKYSLQKKVSEMEQKLQLHllaKEDHHKQLNEIEkyyATITgqfglvkenhgkleqnvqeaIQLNKRLSALNKKQESE 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 946 SNILKAELDNVTS---------LHRQAYE-IEKKLKEQ-IVELQTRLNSELsALEKQKDEKITQ-QEEKYEALIQnlEKD 1013
Cdd:pfam15818 185 ICSLKKELKKVTSdlikskvtcQYKMGEEnINLTIKEQkFQELQERLNMEL-ELNKKINEEITHiQEEKQDIIIS--FQH 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1014 KERLVKNHEQDKEHLIQELNFEKNKAvQTALDEFKVERELVeKELLEKVKHLENQ------IAKTPAFESARE-----DS 1082
Cdd:pfam15818 262 MQQLLQQQTQANTEMEAELKALKENN-QTLERDNELQREKV-KENEEKFLNLQNEhekalgTWKKHVEELNGEineikNE 339
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907067116 1083 SSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVrtsliaeqqTNFNTVLTREKMrkENII 1145
Cdd:pfam15818 340 LSSLKETHIKLQEHYNKLCNQKKFEEDKKFQNVPEV---------NNENSEMSTEKS--ENLI 391
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
821-981 |
3.10e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.76 E-value: 3.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 821 QRIDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEMLKS----LLEQETE 896
Cdd:COG1579 20 DRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNkeyeALQKEIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 897 NLRTEISKLNQKIHDNN---ESYQVGLSELRALMTIEKDQcISELISRHEEESNILKAELDNVTSlhrQAYEIEKKLKEQ 973
Cdd:COG1579 100 SLKRRISDLEDEILELMeriEELEEELAELEAELAELEAE-LEEKKAELDEELAELEAELEELEA---EREELAAKIPPE 175
|
....*...
gi 1907067116 974 IVELQTRL 981
Cdd:COG1579 176 LLALYERI 183
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
647-1151 |
3.38e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 45.43 E-value: 3.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 647 NIIEKVKCSLEITLKEKHQQELQSLKIEYECKldalvKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIK------HE 720
Cdd:TIGR01612 533 NIKAKLYKEIEAGLKESYELAKNWKKLIHEIK-----KELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYINklklelKE 607
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 721 KDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQSREMALEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHiRHTQE 800
Cdd:TIGR01612 608 KIKNISDKNEYIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNELS-SIVKE 686
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 801 FEKVMTDHNMSLEKLKKENQQRIDQM-------LESHASTIQEKEQQLqelklkVSDLSDMRCKLEVELalkeaeTDEIK 873
Cdd:TIGR01612 687 NAIDNTEDKAKLDDLKSKIDKEYDKIqnmetatVELHLSNIENKKNEL------LDIIVEIKKHIHGEI------NKDLN 754
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 874 ILLEESRTQQKEMLKSLLEQETENlrTEISKLNQKI-----HDNNESYQVGLSELRALMTIEKDQCISELISRHEEES-- 946
Cdd:TIGR01612 755 KILEDFKNKEKELSNKINDYAKEK--DELNKYKSKIseiknHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIfk 832
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 947 --NILKAELDNVTSLHRQAYEIEKKLKEQI-------VELQTRLNSELSalekqkDEKITQQEEKYealiqnleKDKERL 1017
Cdd:TIGR01612 833 iiNEMKFMKDDFLNKVDKFINFENNCKEKIdseheqfAELTNKIKAEIS------DDKLNDYEKKF--------NDSKSL 898
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1018 VKNHEQDKEHLIQELNFEKN--------KAVQTALDEFKVERELVEKELLEKVKHLENQIAKTPAFESAREDSsslvaeL 1089
Cdd:TIGR01612 899 INEINKSIEEEYQNINTLKKvdeyikicENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNT------L 972
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907067116 1090 QEKLQEEKAKFLE-QLEEQEKRKNEEMQNVrTSLIAEQQTNFNTVLTREKMRKENIINDLSDK 1151
Cdd:TIGR01612 973 IDKINELDKAFKDaSLNDYEAKNNELIKYF-NDLKANLGKNKENMLYHQFDEKEKATNDIEQK 1034
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
748-1172 |
3.47e-04 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 45.59 E-value: 3.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 748 EIKELKQSREMALEDLKKLHDEKIESLRAEFqcleqNHLKELEDTLHIRH-TQEFEKVMTDHNMSLEKLKKENQQRIDQM 826
Cdd:PTZ00440 429 KIADYALYSNLEIIEIKKKYDEKINELKKSI-----NQLKTLISIMKSFYdLIISEKDSMDSKEKKESSDSNYQEKVDEL 503
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 827 L------ESHASTIQEKEQQLQELKLKVSDLsdmrcKLEVELALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRT 900
Cdd:PTZ00440 504 LqiinsiKEKNNIVNNNFKNIEDYYITIEGL-----KNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEE 578
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 901 EISKLNQKIHDNNESYQV--GLSELRALMTIEKDQCISELISRHEEESNI--------LKAELDNVTSL--HRQAYEIEK 968
Cdd:PTZ00440 579 NVDHIKDIISLNDEIDNIiqQIEELINEALFNKEKFINEKNDLQEKVKYIlnkfykgdLQELLDELSHFldDHKYLYHEA 658
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 969 KLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVK-NHEQDKEHLIQELN--FEKNKAVQTALD 1045
Cdd:PTZ00440 659 KSKEDLQTLLNTSKNEYEKLEFMKSDNIDNIIKNLKKELQNLLSLKENIIKkQLNNIEQDISNSLNqyTIKYNDLKSSIE 738
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1046 EFKverelVEKELLEKVKHLENQIAKTpafesaredsssLVAELQEklQEEKakfleqLEEQEKRKNEEMQNVRTSLIAE 1125
Cdd:PTZ00440 739 EYK-----EEEEKLEVYKHQIINRKNE------------FILHLYE--NDKD------LPDGKNTYEEFLQYKDTILNKE 793
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 1907067116 1126 QQTNFNTVLTRE--KMRKENI--INDLSDKLKS-TMQQQERDKDLIESLSED 1172
Cdd:PTZ00440 794 NKISNDINILKEnkKNNQDLLnsYNILIQKLEAhTEKNDEELKQLLQKFPTE 845
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
678-914 |
3.51e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 45.28 E-value: 3.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 678 KLDALVKDSEENVNKILKLKENLVSLE-EALQNKDNEFTSIKHE-KDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQS 755
Cdd:PRK01156 487 EIEIEVKDIDEKIVDLKKRKEYLESEEiNKSINEYNKIESARADlEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSK 566
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 756 REMALEDLKKLHDEKIESLRAEFQCLEQnHLKELEDTLHirhtqEFEKVMTDHNMSLEKLKKENQQRIDqMLESHASTIQ 835
Cdd:PRK01156 567 RTSWLNALAVISLIDIETNRSRSNEIKK-QLNDLESRLQ-----EIEIGFPDDKSYIDKSIREIENEAN-NLNNKYNEIQ 639
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 836 EKEQQLQELKLKVSDLSDMRCKL-EVELALKE--AETDEIKILLEESRTQQKEMLKSLLEQET--ENLRTEISKLNQKIH 910
Cdd:PRK01156 640 ENKILIEKLRGKIDNYKKQIAEIdSIIPDLKEitSRINDIEDNLKKSRKALDDAKANRARLEStiEILRTRINELSDRIN 719
|
....
gi 1907067116 911 DNNE 914
Cdd:PRK01156 720 DINE 723
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
657-912 |
3.99e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 3.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 657 EITLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHE--KDAIVCVQQEKDQK 734
Cdd:TIGR04523 490 ELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFElkKENLEKEIDEKNKE 569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 735 LLEMekimhtqHCEIKELKQSREMALEDLKKLHDEKIEsLRAEfqcLEQNHLKELEDTLHIRHTQEFEKVMTDHNMSLEK 814
Cdd:TIGR04523 570 IEEL-------KQTQKSLKKKQEEKQELIDQKEKEKKD-LIKE---IEEKEKKISSLEKELEKAKKENEKLSSIIKNIKS 638
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 815 LKKENQQRIDQMLESHASTIQEK---EQQLQELKLKVSDLSDMRCKLEVELAL--KEAETDEIKI----LLEESRTQQKE 885
Cdd:TIGR04523 639 KKNKLKQEVKQIKETIKEIRNKWpeiIKKIKESKTKIDDIIELMKDWLKELSLhyKKYITRMIRIkdlpKLEEKYKEIEK 718
|
250 260
....*....|....*....|....*..
gi 1907067116 886 MLKSLLEQETEnLRTEISKLNQKIHDN 912
Cdd:TIGR04523 719 ELKKLDEFSKE-LENIIKNFNKKFDDA 744
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
759-1175 |
4.29e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 45.03 E-value: 4.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 759 ALEDLKKLHDEKIESLRAEFQCLEQnhlKELEDTLHirhtqEFEKVMTDHNMSLEKLKkENQQRIDQMLESHASTIQEKE 838
Cdd:PRK02224 177 GVERVLSDQRGSLDQLKAQIEEKEE---KDLHERLN-----GLESELAELDEEIERYE-EQREQARETRDEADEVLEEHE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 839 QQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKilleesrtQQKEMLKSLLEQETENL-RTEISKLNQKIhdnnesyq 917
Cdd:PRK02224 248 ERREELETLEAEIEDLRETIAETEREREELAEEVR--------DLRERLEELEEERDDLLaEAGLDDADAEA-------- 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 918 vgLSELRALMTIEKDQCISEL------ISRHEEESNILKAELDNV----TSLHRQAYEIEKKLKEQIVELQTRlNSELSA 987
Cdd:PRK02224 312 --VEARREELEDRDEELRDRLeecrvaAQAHNEEAESLREDADDLeeraEELREEAAELESELEEAREAVEDR-REEIEE 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 988 LEKQKDE------KITQQEEKYEALIQNLEKDKERLvKNHEQDKEHLIQELNFEKNKAvQTALDEFK---VERELVEKEL 1058
Cdd:PRK02224 389 LEEEIEElrerfgDAPVDLGNAEDFLEELREERDEL-REREAELEATLRTARERVEEA-EALLEAGKcpeCGQPVEGSPH 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1059 LEKVKHLENQIAKtpaFESAREDSSSLVAELQEKLqeEKAKFLEQLEEQEKRKNEEMQNVrTSLIAEQQTNFN-TVLTRE 1137
Cdd:PRK02224 467 VETIEEDRERVEE---LEAELEDLEEEVEEVEERL--ERAEDLVEAEDRIERLEERREDL-EELIAERRETIEeKRERAE 540
|
410 420 430
....*....|....*....|....*....|....*...
gi 1907067116 1138 KMRKEniindlSDKLKSTMQQQERDKDLIESLSEDRAR 1175
Cdd:PRK02224 541 ELRER------AAELEAEAEEKREAAAEAEEEAEEARE 572
|
|
| CCDC73 |
pfam15818 |
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ... |
687-1113 |
4.66e-04 |
|
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.
Pssm-ID: 464893 [Multi-domain] Cd Length: 1048 Bit Score: 44.94 E-value: 4.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 687 EENVNKILKLKENLVSLEEALQNKDNefTSIKHEKDAIVCVQQEKDQKL--LEMEKIMHTQHCEIKElkQSREMALEDLK 764
Cdd:pfam15818 27 EEQIGKIIVETQELKWQKETLQNQKE--TLAKQHKEAMAVFKKQLQMKMcaLEEEKGKYQLATEIKE--KEIEGLKETLK 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 765 KLHDEKIeSLraefqcleQNHLKELEDTLHIRHTQEfekvmTDHNMSLEKLKKENQQRIDQ---MLESHASTiqekEQQL 841
Cdd:pfam15818 103 ALQVSKY-SL--------QKKVSEMEQKLQLHLLAK-----EDHHKQLNEIEKYYATITGQfglVKENHGKL----EQNV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 842 QELKLKVSDLSDMRCKLEVELA-----LKEAETDEIKilleESRTQQKEMlksllEQETENLRTEisklNQKIHDNNEsy 916
Cdd:pfam15818 165 QEAIQLNKRLSALNKKQESEICslkkeLKKVTSDLIK----SKVTCQYKM-----GEENINLTIK----EQKFQELQE-- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 917 qvglselRALMTIEKDQCISELISRHEEEsnilkaELDNVTSL-HRQayeiekKLKEQIVELQTRLNSELSALEKQ---- 991
Cdd:pfam15818 230 -------RLNMELELNKKINEEITHIQEE------KQDIIISFqHMQ------QLLQQQTQANTEMEAELKALKENnqtl 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 992 ------KDEKITQQEEKYealiQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQTALDEFKVER---ELVEKELLEKV 1062
Cdd:pfam15818 291 erdnelQREKVKENEEKF----LNLQNEHEKALGTWKKHVEELNGEINEIKNELSSLKETHIKLQEhynKLCNQKKFEED 366
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1907067116 1063 KHLEN-QIAKTPAFESAREDSSSLVAE----LQEKLQEEKAKFLEQLEEQEKRKNE 1113
Cdd:pfam15818 367 KKFQNvPEVNNENSEMSTEKSENLIIQkynsEQEIREENTKSFCSDTEYRETEKKK 422
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
857-1120 |
4.81e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 44.53 E-value: 4.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 857 KLEVeLALKEAETDEIKILLEESRTQQKEMLKSLLEQETENLRTEISKLNQKIhDNNESYQVGLSELRALMTIEKDQCIS 936
Cdd:PRK05771 8 KVLI-VTLKSYKDEVLEALHELGVVHIEDLKEELSNERLRKLRSLLTKLSEAL-DKLRSYLPKLNPLREEKKKVSVKSLE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 937 ELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQ--TRLNSELSAL-------------EKQKDEKITQQEE 1001
Cdd:PRK05771 86 ELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEpwGNFDLDLSLLlgfkyvsvfvgtvPEDKLEELKLESD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1002 KYEALIQNLEKDKERLV----KNHEQDKEHLIQELNFEKN-----KAVQTALDEFKVERELVEKELlekvKHLENQIakt 1072
Cdd:PRK05771 166 VENVEYISTDKGYVYVVvvvlKELSDEVEEELKKLGFERLeleeeGTPSELIREIKEELEEIEKER----ESLLEEL--- 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1907067116 1073 pafesaredssslvAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRT 1120
Cdd:PRK05771 239 --------------KELAKKYLEELLALYEYLEIELERAEALSKFLKT 272
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
811-1057 |
5.44e-04 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 44.25 E-value: 5.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 811 SLEKLKKENQQRIDQMleshastiqekEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQ--KEMLK 888
Cdd:pfam05667 325 TEEELQQQREEELEEL-----------QEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYkvKKKTL 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 889 SLLEQETENlrteISKLNQKIHDNNESyqvgLSELRALMtiEKDQciSELISRHEEesniLKAELDNvtslhrQAYEIEK 968
Cdd:pfam05667 394 DLLPDAEEN----IAKLQALVDASAQR----LVELAGQW--EKHR--VPLIEEYRA----LKEAKSN------KEDESQR 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 969 KLkEQIVELQTRLNsELSALEKQKDEKITQQEEKYEAL----------------IQNLEKDKERLVKNhEQDKEHLIQEL 1032
Cdd:pfam05667 452 KL-EEIKELREKIK-EVAEEAKQKEELYKQLVAEYERLpkdvsrsaytrrileiVKNIKKQKEEITKI-LSDTKSLQKEI 528
|
250 260
....*....|....*....|....*
gi 1907067116 1033 NFEKNKAVQTaldeFKVERELVEKE 1057
Cdd:pfam05667 529 NSLTGKLDRT----FTVTDELVFKD 549
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
608-1171 |
6.09e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 44.66 E-value: 6.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 608 DSHSSIQTIKDDLCHFRTFVQKEQCDLANyLKCTAVEIRNIIEKVKCSLEITLKEK-------HQQELQSLKIEYECKLD 680
Cdd:TIGR01612 1650 DNLNSLQEFLESLKDQKKNIEDKKKELDE-LDSEIEKIEIDVDQHKKNYEIGIIEKikeiaiaNKEEIESIKELIEPTIE 1728
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 681 ALVKDSEENVNKILKLKENLVSLEEALQNKDNEFtsIKHEKDAIVCVqqekdqKLLEMEKIMHTQHCEIKELKQSREMAL 760
Cdd:TIGR01612 1729 NLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEF--IELYNIIAGCL------ETVSKEPITYDEIKNTRINAQNEFLKI 1800
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 761 EDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEFEKV----------------MTDHNMSLEKLKKENQQRID 824
Cdd:TIGR01612 1801 IEIEKKSKSYLDDIEAKEFDRIINHFKKKLDHVNDKFTKEYSKInegfddisksienvknSTDENLLFDILNKTKDAYAG 1880
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 825 QMLESHASTIQEKEQQLQEL-KLKVS-----------DLSDmRCKLEVELALKEAETDEIKILLE-----ESRTQQKEML 887
Cdd:TIGR01612 1881 IIGKKYYSYKDEAEKIFINIsKLANSiniqiqnnsgiDLFD-NINIAILSSLDSEKEDTLKFIPSpekepEIYTKIRDSY 1959
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 888 KSLL------------EQETENLRTEISKLNQKIHDNNESYQVgLSELRalmtIEKDQCISE--LISRHEEESNILKAEL 953
Cdd:TIGR01612 1960 DTLLdifkksqdlhkkEQDTLNIIFENQQLYEKIQASNELKDT-LSDLK----YKKEKILNDvkLLLHKFDELNKLSCDS 2034
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 954 DNVTSLHRQAYEIEKKLKEQIVELQTR---LNSELSALEKQKDEKITQQEEkyealIQNLEKDKERLVKNHEQDKEHLIQ 1030
Cdd:TIGR01612 2035 QNYDTILELSKQDKIKEKIDNYEKEKEkfgIDFDVKAMEEKFDNDIKDIEK-----FENNYKHSEKDNHDFSEEKDNIIQ 2109
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1031 ElnfekNKAVQTALDEFKVERELVEKELLEKvKHLENQIAKTPAfESAREDSSSLVAELQEKLQEEkAKFLEQLEEQEKR 1110
Cdd:TIGR01612 2110 S-----KKKLKELTEAFNTEIKIIEDKIIEK-NDLIDKLIEMRK-ECLLFSYATLVETLKSKVINH-SEFITSAAKFSKD 2181
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907067116 1111 KNEEMQNVRTSL---IAEQQTNFNTVLTREKMrkENIINDLSDKLKSTMQQQERDKDLIESLSE 1171
Cdd:TIGR01612 2182 FFEFIEDISDSLnddIDALQIKYNLNQTKKHM--ISILADATKDHNNLIEKEKEATKIINNLTE 2243
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
834-1110 |
6.42e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 6.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 834 IQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTqqkemlksllEQETENLRTEISKLNQKIhdnn 913
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWD----------EIDVASAEREIAELEAEL---- 677
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 914 ESYQVGLSELRALmtiekdqciselisrhEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKD 993
Cdd:COG4913 678 ERLDASSDDLAAL----------------EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAED 741
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 994 EKITQQEEKYEALIQNLEKDK--ERLVKNHEQDKEHLIQELNfEKNKAVQTALDEFKVERELVEKELlekvkhlenqiak 1071
Cdd:COG4913 742 LARLELRALLEERFAAALGDAveRELRENLEERIDALRARLN-RAEEELERAMRAFNREWPAETADL------------- 807
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1907067116 1072 TPAFESAREdssslVAELQEKLQEE-----KAKFLEQLEEQEKR 1110
Cdd:COG4913 808 DADLESLPE-----YLALLDRLEEDglpeyEERFKELLNENSIE 846
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
656-1175 |
6.61e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 44.26 E-value: 6.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 656 LEITLKEKHQQELQSLKIEYECKL---DALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKD 732
Cdd:PRK02224 192 LKAQIEEKEEKDLHERLNGLESELaelDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETE 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 733 QKLLEMEKIMHTQHCEIKELKQSREMALED--LKKLHDEKIESLRAEFQcleqNHLKELEDTLhirhtQEFEKVMTDHNM 810
Cdd:PRK02224 272 REREELAEEVRDLRERLEELEEERDDLLAEagLDDADAEAVEARREELE----DRDEELRDRL-----EECRVAAQAHNE 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 811 SLEKLKKenqqRIDQmLESHASTIQEK----EQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESrtqqkEM 886
Cdd:PRK02224 343 EAESLRE----DADD-LEERAEELREEaaelESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNA-----ED 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 887 LKSLLEQETENLRTEISKLNQKIhdnnESYQVGLSELRALMTIEK---------DQCISELISRHEEESNILKAELDnvt 957
Cdd:PRK02224 413 FLEELREERDELREREAELEATL----RTARERVEEAEALLEAGKcpecgqpveGSPHVETIEEDRERVEELEAELE--- 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 958 SLHRQAYEIEKKLK--EQIVELQTRLNSelsALEKQKD--EKITQQEEKyealiqnLEKDKERLVKNHEQDKEHliQELN 1033
Cdd:PRK02224 486 DLEEEVEEVEERLEraEDLVEAEDRIER---LEERREDleELIAERRET-------IEEKRERAEELRERAAEL--EAEA 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1034 FEKNKAVQTALDEFKVERELVeKELLEKVKHLENQIaktpafESAR--EDSSSLVAELQEKLQE--EKAKFLEQLEEQEK 1109
Cdd:PRK02224 554 EEKREAAAEAEEEAEEAREEV-AELNSKLAELKERI------ESLEriRTLLAAIADAEDEIERlrEKREALAELNDERR 626
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907067116 1110 RKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLkstmqqqerdkdliESLSEDRAR 1175
Cdd:PRK02224 627 ERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKL--------------DELREERDD 678
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
729-1218 |
6.89e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 44.27 E-value: 6.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 729 QEKDQKLLEMEKIMHTQH----CEIKELKQSREMALEDLKKL---HDEKIESLRAEFQCLEQNHLKELEDTLHIRHTQEF 801
Cdd:TIGR00606 198 QGQKVQEHQMELKYLKQYkekaCEIRDQITSKEAQLESSREIvksYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSR 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 802 EKVMTDHNMSLEKLKKENQQRIDQML----ESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELAlkEAETDEIKILLE 877
Cdd:TIGR00606 278 KKQMEKDNSELELKMEKVFQGTDEQLndlyHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKT--ELLVEQGRLQLQ 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 878 ESRTQQKEMLKSLLEQETEnLRTEISKLnqkihdnnesyqvglsELRALMTIEKDQCISELISRHEEESNILKAELDNVT 957
Cdd:TIGR00606 356 ADRHQEHIRARDSLIQSLA-TRLELDGF----------------ERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQ 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 958 SLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKITQQEEkyealIQNLEKDKERLVKNHEQDKEHLIQELNFEKN 1037
Cdd:TIGR00606 419 SKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKE-----LQQLEGSSDRILELDQELRKAERELSKAEKN 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1038 KAVQTALDEFKVERElvEKELLEKVKHLENQiaktpafESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQN 1117
Cdd:TIGR00606 494 SLTETLKKEVKSLQN--EKADLDRKLRKLDQ-------EMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTS 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1118 VRTSLIAEQQ-------TNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKQLEEEVSKL 1190
Cdd:TIGR00606 565 LLGYFPNKKQledwlhsKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERL 644
|
490 500 510
....*....|....*....|....*....|.
gi 1907067116 1191 RTSSFLSS---APVAAAPELYGACAPELPGE 1218
Cdd:TIGR00606 645 KEEIEKSSkqrAMLAGATAVYSQFITQLTDE 675
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
871-1276 |
7.32e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 44.26 E-value: 7.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 871 EIKILLEESRTQQKEMLKSLLEQET-ENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNIL 949
Cdd:PRK02224 139 EVNKLINATPSDRQDMIDDLLQLGKlEEYRERASDARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAEL 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 950 KAELDNVTSLHRQAYEIEKKLKEQIVELQTRLnSELSALEKQKD---EKITQQEEKYEALIQNLEKDKERLvKNHEQDKE 1026
Cdd:PRK02224 219 DEEIERYEEQREQARETRDEADEVLEEHEERR-EELETLEAEIEdlrETIAETEREREELAEEVRDLRERL-EELEEERD 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1027 HLIQELNFEK--NKAVQTALDEFKVERELVEKELLEK---VKHLENQIaktpafESAREDSSSLVAELQEKlqEEKAKFL 1101
Cdd:PRK02224 297 DLLAEAGLDDadAEAVEARREELEDRDEELRDRLEECrvaAQAHNEEA------ESLREDADDLEERAEEL--REEAAEL 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1102 EqleeqekrknEEMQNVRTSlIAEQQTnfntvlTREKMRKEniINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKK 1181
Cdd:PRK02224 369 E----------SELEEAREA-VEDRRE------EIEELEEE--IEELRERFGDAPVDLGNAEDFLEELREERDELREREA 429
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1182 QLEEEVSKLRTSsflssapVAAAPELYGA-----CAPELPGEPERSVMETADEGRLDSAMETSMMSVQENMLSEEKQRIM 1256
Cdd:PRK02224 430 ELEATLRTARER-------VEEAEALLEAgkcpeCGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAE 502
|
410 420
....*....|....*....|...
gi 1907067116 1257 LL---ERTLQLKEEENKRLNQRL 1276
Cdd:PRK02224 503 DLveaEDRIERLEERREDLEELI 525
|
|
| ATG17_like |
pfam04108 |
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ... |
114-339 |
8.73e-04 |
|
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ATG17 and ATG11, conserved across eukaryotes. ATG17 forms a complex with ATG29 and ATG31, critical for both PAS (preautophagosomal structure) formation and autophagy. Together with ATG13, it is required for ATG1 kinase activation. ATG11 is a scaffold protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway during starvation and to recruit ATG proteins to the pre-autophagosome. It is also required for ATG1 kinase activation. In many eukaryotes, ATG11 (the orthologue in mammals is RB1-inducible coiled-coil protein 1 (RB1CC1) and in S. pombe is Taz1-interacting factor 1 (taf1)) is essential for bulk autophagy, except in S.cerevisiae. ATG17 and ATG11 are large similar proteins, both predicted to be almost entirely helical, containing conserved coiled-coil regions and lack obvious functional motifs.
Pssm-ID: 427715 [Multi-domain] Cd Length: 360 Bit Score: 43.15 E-value: 8.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 114 NVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAikgLEDRLYALDQMIASCSRLVNEQKELAQG 193
Cdd:pfam04108 127 ELQAAQESLDSDLKRFDDDLRDLQKELESLSSPSESISLIPTLLKELES---LEEEMASLLESLTNHYDQCVTAVKLTEG 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 194 FLANqMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHV------RLKWCCFVMLHADQDG 267
Cdd:pfam04108 204 GRAE-MLEVLENDARELDDVVPELQDRLDEMENNYERLQKLLEQKNSLIDELLSALQLiaeiqsRLPEYLAALKEFEERW 282
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907067116 268 EKLQALLRLVIELLERVRivEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESF 339
Cdd:pfam04108 283 EEEKETIEDYLSELEDLR--EFYEGFPSAYGSLLLEVERRREWAEKMKKILRKLAEELDRLQEEERKRREKF 352
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
988-1153 |
9.72e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.61 E-value: 9.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 988 LEKQKDEKITQQEEKYEALIQNLEKDKERLvknheqdkehliqelnfeKNKAVQTALDEFKVERELVEKELLEKVKHLEN 1067
Cdd:PRK12704 25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAI------------------KKEALLEAKEEIHKLRNEFEKELRERRNELQK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1068 QIAKTPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKnEEMQNvrtsLIAEQQTNFNTV--LTREKMRKEnII 1145
Cdd:PRK12704 87 LEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKE-EELEE----LIEEQLQELERIsgLTAEEAKEI-LL 160
|
....*...
gi 1907067116 1146 NDLSDKLK 1153
Cdd:PRK12704 161 EKVEEEAR 168
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
639-1041 |
1.16e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 43.41 E-value: 1.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 639 KCTAVEIRNIIEKVKCSLEITLKEKHQQEL-QSLKIEYECKLDALVKDSEENVNKILKLKE-NLVSLEEALQNKDNEFTS 716
Cdd:COG5185 143 LDEIADIEASYGEVETGIIKDIFGKLTQELnQNLKKLEIFGLTLGLLKGISELKKAEPSGTvNSIKESETGNLGSESTLL 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 717 IKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKE-LKQSREMALEDLK------KLHDEKIESLRAEFQCLEQNhLKEL 789
Cdd:COG5185 223 EKAKEIINIEEALKGFQDPESELEDLAQTSDKLEKlVEQNTDLRLEKLGenaessKRLNENANNLIKQFENTKEK-IAEY 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 790 EDTLHIR-HTQEFEKVM--TDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLSDmrcklEVELALKE 866
Cdd:COG5185 302 TKSIDIKkATESLEEQLaaAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVG-----EVELSKSS 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 867 AETDEIKILLEESRT-----------QQKEMLKSL------LEQETENLRTEISKLNQKIHDNNESYQVGLSELRALMTI 929
Cdd:COG5185 377 EELDSFKDTIESTKEsldeipqnqrgYAQEILATLedtlkaADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMRE 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 930 EKDQCISELISRHEEESNILKAELDNVTSLHRQAYEIEKKLKEQIVELQTRLNSELSALEKQKDEKI-------TQQEEK 1002
Cdd:COG5185 457 ADEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAeslkdfmRARGYA 536
|
410 420 430
....*....|....*....|....*....|....*....
gi 1907067116 1003 YEALIQNLEKDKERLVKNHEQDKEHLIQELNFEKNKAVQ 1041
Cdd:COG5185 537 HILALENLIPASELIQASNAKTDGQAANLRTAVIDELTQ 575
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
936-1161 |
2.12e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 42.58 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 936 SELISRHEEESNILKAELDNVTSLHRQAyeiekklkeqivelqTRLNSELSALEKQKDEKITQQEEKyealIQNLEKDKE 1015
Cdd:PLN02939 63 SKLQSNTDENGQLENTSLRTVMELPQKS---------------TSSDDDHNRASMQRDEAIAAIDNE----QQTNSKDGE 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1016 RLVKNHEQDKEHLIQelNFEKN-----KAVQTALDEfkVERELVEKELLE-KVKHLENQIAKTPAfesaredssslvael 1089
Cdd:PLN02939 124 QLSDFQLEDLVGMIQ--NAEKNilllnQARLQALED--LEKILTEKEALQgKINILEMRLSETDA--------------- 184
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907067116 1090 QEKLQEEKAKFLEQLEEQ-EKRKNEEMQNVRTSLIAEQQTNFN-TVLTREKMRKENIINDLSDKLKSTMQQQER 1161
Cdd:PLN02939 185 RIKLAAQEKIHVEILEEQlEKLRNELLIRGATEGLCVHSLSKElDVLKEENMLLKDDIQFLKAELIEVAETEER 258
|
|
| GOLGA2L5 |
pfam15070 |
Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein ... |
812-1108 |
2.53e-03 |
|
Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein family remains unknown. This family of proteins is thought to be found in the Golgi apparatus of eukaryotes.
Pssm-ID: 464485 [Multi-domain] Cd Length: 521 Bit Score: 41.97 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 812 LEKLKKEN---QQRIDQMLESHASTIQEKEQ---QLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKE 885
Cdd:pfam15070 17 AENLKEEGavwQQKMQQLSEQVRTLREEKERsvsQVQELETSLAELKNQAAVPPAEEEQPPAGPSEEEQRLQEEAEQLQK 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 886 MLKSLLEQETENLR--TEISKLNQK-------IHDNNESY-QVGLSELRALMTIEKDQC-ISELISRHEEESNILkAELD 954
Cdd:pfam15070 97 ELEALAGQLQAQVQdnEQLSRLNQEqeqrlleLERAAERWgEQAEDRKQILEDMQSDRAtISRALSQNRELKEQL-AELQ 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 955 N-----------VTSLHRQAYEIEKKLKEQIVELQTRL----------NSELSALEKQKDEKITQQEEkYEALIQNLEKD 1013
Cdd:pfam15070 176 NgfvkltnenmeLTSALQSEQHVKKELAKKLGQLQEELgelketlelkSQEAQSLQEQRDQYLAHLQQ-YVAAYQQLASE 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1014 KERLVKNHEQdKEHLIQELNFEKnkaVQTaldefKVERELVEKELLEKVKHLenqiaktpafESAREDSSSLVAELQEKL 1093
Cdd:pfam15070 255 KEELHKQYLL-QTQLMDRLQHEE---VQG-----KVAAEMARQELQETQERL----------EALTQQNQQLQAQLSLLA 315
|
330
....*....|....*
gi 1907067116 1094 QEEKAKFLEQLEEQE 1108
Cdd:pfam15070 316 NPGEGDGLESEEEEE 330
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
629-908 |
2.62e-03 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 42.16 E-value: 2.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 629 KEQCDLANYLKCTAVEIRNIIEKVKCSLEITLKEKHQQELQSLKIEYECKldalvkdSEENVNKILKLKENLVSLEEALQ 708
Cdd:pfam02029 80 QEALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYK-------EEETEIREKEYQENKWSTEVRQA 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 709 NKDNEftsiKHEKDAIVCVQQEKDQKLLEMEKIMHTQhceiKELKQSREM-ALEDLKKLHDE-KIESLRAEFQCLEQNHL 786
Cdd:pfam02029 153 EEEGE----EEEDKSEEAEEVPTENFAKEEVKDEKIK----KEKKVKYESkVFLDQKRGHPEvKSQNGEEEVTKLKVTTK 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 787 KELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQRIDQMLESHASTIQEKEQQLQELKLKvsdLSDMRCKLEVELALKE 866
Cdd:pfam02029 225 RRQGGLSQSQEREEEAEVFLEAEQKLEELRRRRQEKESEEFEKLRQKQQEAELELEELKKK---REERRKLLEEEEQRRK 301
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1907067116 867 AETDEIKILLEESRTQQKEmlkslleqETENLRTEISKLNQK 908
Cdd:pfam02029 302 QEEAERKLREEEEKRRMKE--------EIERRRAEAAEKRQK 335
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
749-1011 |
2.87e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 42.22 E-value: 2.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 749 IKELKQSREMALEDLK-KLHDEKIESLRAEFQcleqnHLKELEDTLhiRHTQEFEKVMTDHNMSLEKLKKEN-QQRIDQM 826
Cdd:PRK05771 22 LEALHELGVVHIEDLKeELSNERLRKLRSLLT-----KLSEALDKL--RSYLPKLNPLREEKKKVSVKSLEElIKDVEEE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 827 LESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEaetdEIKILLEESRTQQKemLKSLLEQETENLRTEISKLN 906
Cdd:PRK05771 95 LEKIEKEIKELEEEISELENEIKELEQEIERLEPWGNFDL----DLSLLLGFKYVSVF--VGTVPEDKLEELKLESDVEN 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 907 QKIHDNNESYQ----VGLSELRALmtiekdqcISELISRHEEESNILKAEldnvtslhRQAYEIEKKLKEQIVELQT--- 979
Cdd:PRK05771 169 VEYISTDKGYVyvvvVVLKELSDE--------VEEELKKLGFERLELEEE--------GTPSELIREIKEELEEIEKere 232
|
250 260 270
....*....|....*....|....*....|..
gi 1907067116 980 RLNSELSALEKQKDEKITQQEEKYEALIQNLE 1011
Cdd:PRK05771 233 SLLEELKELAKKYLEELLALYEYLEIELERAE 264
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
960-1080 |
2.96e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.07 E-value: 2.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 960 HRQAYEIEKKLKEQIVELQT----------RLNSELSALEKqKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLI 1029
Cdd:PRK12704 67 HKLRNEFEKELRERRNELQKlekrllqkeeNLDRKLELLEK-REEELEKKEKELEQKQQELEKKEEELEELIEEQLQELE 145
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1907067116 1030 QELNFEKNKAVQTALDefKVERELvEKELLEKVKHLENQiAKTPAFESARE 1080
Cdd:PRK12704 146 RISGLTAEEAKEILLE--KVEEEA-RHEAAVLIKEIEEE-AKEEADKKAKE 192
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
736-1122 |
3.75e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 41.76 E-value: 3.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 736 LEMEKImhtqhcEIKELKQSREmaLEDLKKLH-----DEKIESLRAEFQCLEQNHLKELEDTLHirhtqefekvmtDHNM 810
Cdd:pfam06160 15 LEERKN------ELMNLPVQEE--LSKVKKLNltgetQEKFEEWRKKWDDIVTKSLPDIEELLF------------EAEE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 811 SLEKLK----KENQQRIDQMLESHASTIQEKEQQLQELklkvsdlsdmrckLEVElalkEAETDEIKILLEESRTQQKEM 886
Cdd:pfam06160 75 LNDKYRfkkaKKALDEIEELLDDIEEDIKQILEELDEL-------------LESE----EKNREEVEELKDKYRELRKTL 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 887 LK---------SLLEQETENLRTEISKLNQKIH--DNNESYQVgLSELRAlMTIEKDQCISELISRHEEESNILKAELDN 955
Cdd:pfam06160 138 LAnrfsygpaiDELEKQLAEIEEEFSQFEELTEsgDYLEAREV-LEKLEE-ETDALEELMEDIPPLYEELKTELPDQLEE 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 956 VTSLHRQA----YEIE-KKLKEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNL------EKDKERLVKNHEQD 1024
Cdd:pfam06160 216 LKEGYREMeeegYALEhLNVDKEIQQLEEQLEENLALLENLELDEAEEALEEIEERIDQLydllekEVDAKKYVEKNLPE 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1025 KEHLIQELNfEKNKAVQTALDEFKVERELVEKELlEKVKHLENQIA---------------KTPAFESAREDSSSLVAEL 1089
Cdd:pfam06160 296 IEDYLEHAE-EQNKELKEELERVQQSYTLNENEL-ERVRGLEKQLEelekrydeiverleeKEVAYSELQEELEEILEQL 373
|
410 420 430
....*....|....*....|....*....|....*
gi 1907067116 1090 Q--EKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSL 1122
Cdd:pfam06160 374 EeiEEEQEEFKESLQSLRKDELEAREKLDEFKLEL 408
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
664-1166 |
3.92e-03 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 41.66 E-value: 3.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 664 HQQELQSLKIEYECKLDALVKDSEenvnkilKLKENLVSLEEALQNKDNEFTSIKHEKDaIVCVQQEKDQKLLEM----- 738
Cdd:pfam07111 149 HQEQLSSLTQAHEEALSSLTSKAE-------GLEKSLNSLETKRAGEAKQLAEAQKEAE-LLRKQLSKTQEELEAqvtlv 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 739 --------EKIMHTQHCEIKELKqsREMALEDLKKLHDEK------IESLRAEFQCLEQN-HLKELEDTLHIRHTQEFEK 803
Cdd:pfam07111 221 eslrkyvgEQVPPEVHSQTWELE--RQELLDTMQHLQEDRadlqatVELLQVRVQSLTHMlALQEEELTRKIQPSDSLEP 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 804 VMTDHNMSL-----EKLKKENQQRIDQMLEsHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAETD----EIKI 874
Cdd:pfam07111 299 EFPKKCRSLlnrwrEKVFALMVQLKAQDLE-HRDSVKQLRGQVAELQEQVTSQSQEQAILQRALQDKAAEVEvermSAKG 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 875 L------LEESRTQQKEMLKSLLEQ----------ETENLRTEISKLNQKIH-----DNNESYQVglselRALMTIEKDQ 933
Cdd:pfam07111 378 LqmelsrAQEARRRQQQQTASAEEQlkfvvnamssTQIWLETTMTRVEQAVAripslSNRLSYAV-----RKVHTIKGLM 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 934 CISELISRHEEESNILKAELDNVTSlhrqayEIEKKLkEQIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKD 1013
Cdd:pfam07111 453 ARKVALAQLRQESCPPPPPAPPVDA------DLSLEL-EQLREERNRLDAELQLSAHLIQQEVGRAREQGEAERQQLSEV 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1014 KERLVKNHEQDKEHLI---QELNFEKNKAVQTALDEFKVERELVEKELLEKvkhlenqiaktpafesaredssslvAELQ 1090
Cdd:pfam07111 526 AQQLEQELQRAQESLAsvgQQLEVARQGQQESTEEAASLRQELTQQQEIYG-------------------------QALQ 580
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1091 EKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDK-----LKSTMQQQERDKDL 1165
Cdd:pfam07111 581 EKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERNQELRRLQDEARKeegqrLARRVQELERDKNL 660
|
.
gi 1907067116 1166 I 1166
Cdd:pfam07111 661 M 661
|
|
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
817-990 |
4.02e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 41.58 E-value: 4.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 817 KENQQRIDQMLESHASTIQEKEQQLQELKLKVSDLS---DMRCKLEVELALKEAETDEIKILLEESRtqqKEMLKSL--- 890
Cdd:pfam13166 282 TEFQNRLQKLIEKVESAISSLLAQLPAVSDLASLLSafeLDVEDIESEAEVLNSQLDGLRRALEAKR---KDPFKSIeld 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 891 -LEQETENLRTEISKLNQKIHDNNEsyqvGLSELRALMTIEKDQ----CISELISRHEEESNILKAELDNVTSLHRQAYE 965
Cdd:pfam13166 359 sVDAKIESINDLVASINELIAKHNE----ITDNFEEEKNKAKKKlrlhLVEEFKSEIDEYKDKYAGLEKAINSLEKEIKN 434
|
170 180
....*....|....*....|....*...
gi 1907067116 966 IE---KKLKEQIVELQTRLNSELSALEK 990
Cdd:pfam13166 435 LEaeiKKLREEIKELEAQLRDHKPGADE 462
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
949-1161 |
4.04e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 4.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 949 LKAELDNVTSLHRQAYEIEKKLKEQIVELQT---RLNSELSALEKQKDEkITQQEEKYEALIQNLEKDKERLVKNHEQDK 1025
Cdd:COG4942 25 AEAELEQLQQEIAELEKELAALKKEEKALLKqlaALERRIAALARRIRA-LEQELAALEAELAELEKEIAELRAELEAQK 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1026 EHLIQELNF----EKNKAVQTALDEFKVERELVEKELLEKV-KHLENQIAktpAFESAREDSSSLVAELQEKlQEEKAKF 1100
Cdd:COG4942 104 EELAELLRAlyrlGRQPPLALLLSPEDFLDAVRRLQYLKYLaPARREQAE---ELRADLAELAALRAELEAE-RAELEAL 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907067116 1101 LEQLEEQEKRKNEEMQNvRTSLIAEQQTNFNTVLTR--EKMRKENIINDLSDKLKSTMQQQER 1161
Cdd:COG4942 180 LAELEEERAALEALKAE-RQKLLARLEKELAELAAElaELQQEAEELEALIARLEAEAAAAAE 241
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
676-1158 |
5.73e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.19 E-value: 5.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 676 ECKLDALVKDSEenvNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQKLLEMEKIMHTQHCEIKELKQS 755
Cdd:TIGR00606 690 EAELQEFISDLQ---SKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKND 766
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 756 REMALEDLKKL--HDEKIESLRAEFQCLEQNHLkELEDTLHIRHTQEFEKVMTDHNMSLEKLKKENQQR------IDQML 827
Cdd:TIGR00606 767 IEEQETLLGTImpEEESAKVCLTDVTIMERFQM-ELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqheldtVVSKI 845
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 828 ESHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAetdeikilleesrtqqkemlkslLEQETENLRTEISKLNQ 907
Cdd:TIGR00606 846 ELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQ-----------------------FEEQLVELSTEVQSLIR 902
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 908 KIHDNNEsyqvglSELRALMTIEKDQC-ISELISRHEEESNILKAELDnvtslhrqayEIEKKLKEQIVELQTRLNSels 986
Cdd:TIGR00606 903 EIKDAKE------QDSPLETFLEKDQQeKEELISSKETSNKKAQDKVN----------DIKEKVKNIHGYMKDIENK--- 963
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 987 aLEKQKDEKITQQEEKYEALIQNLEKDKERLvKNHEQDKEHLIQELNFEKNKA--VQTALDEFKVERELveKELLEKVKH 1064
Cdd:TIGR00606 964 -IQDGKDDYLKQKETELNTVNAQLEECEKHQ-EKINEDMRLMRQDIDTQKIQErwLQDNLTLRKRENEL--KEVEEELKQ 1039
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1065 LENQIAKTPAFESAREDSsslvaELQEKLQ---EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRK 1141
Cdd:TIGR00606 1040 HLKEMGQMQVLQMKQEHQ-----KLEENIDlikRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKYREMMIVMRTTE 1114
|
490
....*....|....*..
gi 1907067116 1142 EnIINDLsDKLKSTMQQ 1158
Cdd:TIGR00606 1115 L-VNKDL-DIYYKTLDQ 1129
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
807-1070 |
6.23e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 41.07 E-value: 6.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 807 DHNMSLEKLKkENQQRIDQMLeSHASTIQEKEQQLQELKLKVSDLSDMRCKLEVELALKEAEtDEIKILLEEsRTQQKEM 886
Cdd:PRK05771 40 LSNERLRKLR-SLLTKLSEAL-DKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIE-KEIKELEEE-ISELENE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 887 LKSLLEQETE-----NLRTEISKLNqkihdNNESYQVGLSELRA----LMTIEKDQCISELISRHEEESNILkaeldnVT 957
Cdd:PRK05771 116 IKELEQEIERlepwgNFDLDLSLLL-----GFKYVSVFVGTVPEdkleELKLESDVENVEYISTDKGYVYVV------VV 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 958 SLHRQAYEIEKKLKE-QIVELQTRLNSELSALEKQKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDKEHLIQELNFEK 1036
Cdd:PRK05771 185 VLKELSDEVEEELKKlGFERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELERAE 264
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1907067116 1037 nkavqtALDEFKVEREL------VEKELLEKVKHLENQIA 1070
Cdd:PRK05771 265 ------ALSKFLKTDKTfaiegwVPEDRVKKLKELIDKAT 298
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
661-842 |
7.01e-03 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 40.90 E-value: 7.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 661 KEKHQQELQSLKIEYECKLDALVKDSEENVNK-ILKLKENLVSLEEALQN-KDNEFtsiKHEKDAIVcvQQEKDQKLLEM 738
Cdd:pfam09731 256 RIVFQQELVSIFPDIIPVLKEDNLLSNDDLNSlIAHAHREIDQLSKKLAElKKREE---KHIERALE--KQKEELDKLAE 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 739 EKIMHTQHCEIKELKQSR---EMALEDLKKLHDEKIES-LRAEFQCLEQ---NHLKELEDTLHIRHTQEF-EKVMTDHNM 810
Cdd:pfam09731 331 ELSARLEEVRAADEAQLRlefEREREEIRESYEEKLRTeLERQAEAHEEhlkDVLVEQEIELQREFLQDIkEKVEEERAG 410
|
170 180 190
....*....|....*....|....*....|....*.
gi 1907067116 811 SLEKLKK--ENQQRIDQMLESHASTIQE--KEQQLQ 842
Cdd:pfam09731 411 RLLKLNEllANLKGLEKATSSHSEVEDEnrKAQQLW 446
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
976-1191 |
7.15e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.52 E-value: 7.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 976 ELQTRLNSELSALEKQKDE---KITQQEEKYEALIQNLEKDKERLVKNHEQdkehlIQELNfEKNKAVQTALDEFKVERE 1052
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAElekELAALKKEEKALLKQLAALERRIAALARR-----IRALE-QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1053 LVEKELLEKVKHLENQIAKtpAFESAREDSSSLVAELQEKLQEEK-AKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTnfn 1131
Cdd:COG4942 94 ELRAELEAQKEELAELLRA--LYRLGRQPPLALLLSPEDFLDAVRrLQYLKYLAPARREQAEELRADLAELAALRAE--- 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1132 tvLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEekkqleeEVSKLR 1191
Cdd:COG4942 169 --LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAA-------ELAELQ 219
|
|
| Metal_resist |
pfam13801 |
Heavy-metal resistance; This is a metal-binding protein which is involved in resistance to ... |
1026-1104 |
8.02e-03 |
|
Heavy-metal resistance; This is a metal-binding protein which is involved in resistance to heavy-metal ions. The protein forms a four-helix hooked hairpin, consisting of two long alpha helices each flanked by a shorter alpha helix. It binds a metal ion in a type-2 like centre. It contains two copies of an LTXXQ motif.
Pssm-ID: 433488 [Multi-domain] Cd Length: 119 Bit Score: 37.66 E-value: 8.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 1026 EHLIQELNFEKNKAVQTALDEFKVERELVEKELLEKVKHLENQIAKTP----AFESAREDSSSLVAELQEKLQEEKAKFL 1101
Cdd:pfam13801 33 LRAALGLPAEQRERLRAALRDHARELRALRRELRAARRELAALLAAPPfdpaAIEAALAEARQARAALQAQIEEALLEFA 112
|
...
gi 1907067116 1102 EQL 1104
Cdd:pfam13801 113 ATL 115
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
575-889 |
8.03e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 40.82 E-value: 8.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 575 SRRMQDTSTRGNEGFGDRAALHVQLEKCRAAAQDSHSSIQTIKDDLCHFRTFVQKEQCDLANYLKCTAVEIRNIIEKVKC 654
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLER 308
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 655 SLEitLKEKHQQELQSLKIEYECKLDALVKDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVCVQQEKDQK 734
Cdd:TIGR02169 309 SIA--EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 735 LLEMEKIMHTQHCEIKELKQSREMALEDLKKLHdEKIESLRAEFQCLEQNHLkeledtlhirhtqEFEKVMTDHNMSLEK 814
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLQEELQRLS-EELADLNAAIAGIEAKIN-------------ELEEEKEDKALEIKK 452
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250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907067116 815 lKKENQQRIDQMLESHastiqekEQQLQELKLKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQkEMLKS 889
Cdd:TIGR02169 453 -QEWKLEQLAADLSKY-------EQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE-EVLKA 518
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|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
650-1068 |
8.33e-03 |
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exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 40.72 E-value: 8.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 650 EKVKCSLEITLKEKHQQELQSLK---IEYECKLDALVkDSEENVNKILKLKENLVSLEEALQNKDNEFTSIKHEKDAIVC 726
Cdd:TIGR00618 485 ETRKKAVVLARLLELQEEPCPLCgscIHPNPARQDID-NPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKE 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 727 VQQEKDQKLLEMEKIMHTQHCEIKELKQsremALEDLKKLHDEKIEsLRAEFQCLEQNHLKELEDTLH----IRHTQEFE 802
Cdd:TIGR00618 564 QMQEIQQSFSILTQCDNRSKEDIPNLQN----ITVRLQDLTEKLSE-AEDMLACEQHALLRKLQPEQDlqdvRLHLQQCS 638
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 803 KVMTDHNMSLEKLKKENQQriDQMLESHASTIQEKEQQLQELKLKVSDLSDMRCKLEV---ELALKEAETDEIKILLEES 879
Cdd:TIGR00618 639 QELALKLTALHALQLTLTQ--ERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYwkeMLAQCQTLLRELETHIEEY 716
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 880 RTQQKEM------LKSLLEQETENLRTEISKLNQKI-----HDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNI 948
Cdd:TIGR00618 717 DREFNEIenasssLGSDLAAREDALNQSLKELMHQArtvlkARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREE 796
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907067116 949 LKAELDNVTSLHRQ-AYEIEKKLKEQIVELQTRLNSELSALEK--QKDEKITQQEEKYEALIQNLEKDKERLVKNHEQDK 1025
Cdd:TIGR00618 797 DTHLLKTLEAEIGQeIPSDEDILNLQCETLVQEEEQFLSRLEEksATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSD 876
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1907067116 1026 ehliqELNFEKNKAVQTALDEFkveRELVEKELLEKVKHLENQ 1068
Cdd:TIGR00618 877 -----KLNGINQIKIQFDGDAL---IKFLHEITLYANVRLANQ 911
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