NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1907198995|ref|XP_036011004|]
View 

golgin subfamily A member 4 isoform X14 [Mus musculus]

Protein Classification

GRIP and coiled-coil domain-containing protein( domain architecture ID 13380436)

GRIP and coiled-coil domain-containing protein similar to Mus musculus GRIP and coiled-coil domain-containing protein 1 that is probably involved in maintaining Golgi structure

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 697-1303 1.87e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.87e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  697 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 774
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  775 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 854
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  855 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 934
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  935 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 1013
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1014 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1089
Cdd:COG1196    487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1090 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1169
Cdd:COG1196    567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1170 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1249
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198995 1250 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1303
Cdd:COG1196    720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 364-898 3.89e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 88.46  E-value: 3.89e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  364 LLLSEKEALQEQLDERLQELEKmkgmvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQ---------KEKSE 434
Cdd:COG1196    229 LLLLKLRELEAELEELEAELEE-----LEAELEELEAELAELEAELEELRLELEELELELEEAQAEeyellaelaRLEQD 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  435 RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELsrvrQEAASMAKNSEEQVAALQKLHAEELA 514
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL----EEAEAELAEAEEALLEAEAELAEAEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  515 SKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRIL 594
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  595 ELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEG-------LQQQQDSLWTE--RLQSLSQQHQAA 665
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLegvkaalLLAGLRGLAGAvaVLIGVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  666 VEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQAL 745
Cdd:COG1196    540 LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  746 EAELEEQRRHHQREVGSI----SEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL 821
Cdd:COG1196    620 DTLLGRTLVAARLEAALRravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  822 AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQ----VVEMETHKKHVCEELDAQRAQVQQLERQRSEL 897
Cdd:COG1196    700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEeeelLEEEALEELPEPPDLEELERELERLEREIEAL 779


                   .
gi 1907198995  898 E 898
Cdd:COG1196    780 G 780
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1023-1717 1.79e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 1.79e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1023 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1097
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1098 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1177
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1178 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1257
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1258 SRDKAD----AILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1333
Cdd:TIGR02168  420 QQEIEEllkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1334 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1403
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1404 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1459
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1460 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1523
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1524 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1590
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1591 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1670
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198995 1671 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1493-2161 1.88e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.88e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1493 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1572
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1573 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1652
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1653 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1732
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1733 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1809
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1810 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1862
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1863 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1925
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1926 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 2005
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2006 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2085
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2086 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2160
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907198995 2161 A 2161
Cdd:TIGR02168  910 R 910
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2186-2229 3.58e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.45  E-value: 3.58e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907198995  2186 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2229
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 697-1303 1.87e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.87e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  697 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 774
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  775 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 854
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  855 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 934
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  935 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 1013
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1014 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1089
Cdd:COG1196    487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1090 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1169
Cdd:COG1196    567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1170 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1249
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198995 1250 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1303
Cdd:COG1196    720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 697-1403 3.03e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.52  E-value: 3.03e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  697 EKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRGDADKMkQALEAELEEQRRHHQREVGSISEQQELTVRRAEK 776
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  777 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 855
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  856 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ----RSELEEKVRSLAQLQDsQLKNSTVEKEQA---RQSLME 928
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEledlRAELEEVDKEFAETRD-ELKDYREKLEKLkreINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  929 KENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA---KLKKELE 1005
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1006 NTVLELSQKEKQ---------FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 1076
Cdd:TIGR02169  487 KLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1077 LRDKHA--------EQMEEKEQGLGELRQK------VRIVQSEKEELTKEVARLKEAVSGQDVALA----------GLQG 1132
Cdd:TIGR02169  567 LKRRKAgratflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAArrlmgkyrmvTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1133 QLEQKSAVIVSLSERESQLQS-------QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1205
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1206 SCKSLHELSK----------KSLEDKSLNLKSLLEELASQLDSRcERTKALLEAKTNELvctsrdKADAILARLSQCQRH 1275
Cdd:TIGR02169  727 QLEQEEEKLKerleeleedlSSLEQEIENVKSELKELEARIEEL-EEDLHKLEEALNDL------EARLSHSRIPEIQAE 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1276 TATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASE 1355
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198995 1356 KESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLE 1403
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 364-898 3.89e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 88.46  E-value: 3.89e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  364 LLLSEKEALQEQLDERLQELEKmkgmvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQ---------KEKSE 434
Cdd:COG1196    229 LLLLKLRELEAELEELEAELEE-----LEAELEELEAELAELEAELEELRLELEELELELEEAQAEeyellaelaRLEQD 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  435 RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELsrvrQEAASMAKNSEEQVAALQKLHAEELA 514
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL----EEAEAELAEAEEALLEAEAELAEAEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  515 SKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRIL 594
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  595 ELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEG-------LQQQQDSLWTE--RLQSLSQQHQAA 665
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLegvkaalLLAGLRGLAGAvaVLIGVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  666 VEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQAL 745
Cdd:COG1196    540 LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  746 EAELEEQRRHHQREVGSI----SEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL 821
Cdd:COG1196    620 DTLLGRTLVAARLEAALRravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  822 AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQ----VVEMETHKKHVCEELDAQRAQVQQLERQRSEL 897
Cdd:COG1196    700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEeeelLEEEALEELPEPPDLEELERELERLEREIEAL 779


                   .
gi 1907198995  898 E 898
Cdd:COG1196    780 G 780
PTZ00121 PTZ00121
MAEBL; Provisional
 368-1088 1.00e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 87.50  E-value: 1.00e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  368 EKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAA--FEELEKA- 444
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAArkAEEVRKAe 1191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  445 -LSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAEELASKEQELSRR 523
Cdd:PTZ00121  1192 eLRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAA 1271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  524 LEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKailTESENKLQELGQEAEAYRTRILEletsLEKS 603
Cdd:PTZ00121  1272 IKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKA---DEAKKKAEEAKKKADAAKKKAEE----AKKA 1344

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  604 LQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKE 683
Cdd:PTZ00121  1345 AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK 1424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  684 KESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSI 763
Cdd:PTZ00121  1425 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKK 1504

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  764 SEQQEltvRRAEKALKDELSRLGALLDERDEHLRERQARvqdlEAHLQKSAGELQQAlakLDLLHSEQSAAREQAGAYEE 843
Cdd:PTZ00121  1505 AAEAK---KKADEAKKAEEAKKADEAKKAEEAKKADEAK----KAEEKKKADELKKA---EELKKAEEKKKAEEAKKAEE 1574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  844 QLAQMQQKVLDL-ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKvrslaQLQDSQLKNSTVEKEQA 922
Cdd:PTZ00121  1575 DKNMALRKAEEAkKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK-----KKVEQLKKKEAEEKKKA 1649

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  923 RQSLMEKENIILQMREEQAKEIEILKQTLSSKEEsisilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 1002
Cdd:PTZ00121  1650 EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA------EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1003 ELENTVLELSQKEKQFNAQILEMAQAnsagisdtvsRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHA 1082
Cdd:PTZ00121  1724 AEEENKIKAEEAKKEAEEDKKKAEEA----------KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRR 1793


                   ....*.
gi 1907198995 1083 EQMEEK 1088
Cdd:PTZ00121  1794 MEVDKK 1799
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 412-1219 7.12e-15

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 80.93  E-value: 7.12e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  412 LRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDaqrrMKMEMDEQMKAVERASE-EERLRLQ-----HELS 485
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQE----MQMERDAMADIRRRESQsQEDLRNQlqntvHELE 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  486 RVRQEAASMAKNSEEQVAALQKLhaeelaskeqelsrrLEARERELQEqmrialekSRSEYLKLTQEKEQQESLALEELE 565
Cdd:pfam15921  156 AAKCLKEDMLEDSNTQIEQLRKM---------------MLSHEGVLQE--------IRSILVDFEEASGKKIYEHDSMST 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  566 LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaekNKHNKELTALAEQHRTEVEGLQQ 645
Cdd:pfam15921  213 MHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLL-------QQHQDRIEQLISEHEVEITGLTE 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  646 QQDSLWTERlQSLSQQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRA 723
Cdd:pfam15921  286 KASSARSQA-NSIQSQLEIIQEQARNQNSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTE 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  724 RDQLAEElsvlRGDADKMKQALEAELeeqrrhHQREvgsiseqQELTVRRAE-KALKDELSRLGALLDERDEHLRERQAR 802
Cdd:pfam15921  365 RDQFSQE----SGNLDDQLQKLLADL------HKRE-------KELSLEKEQnKRLWDRDTGNSITIDHLRRELDDRNME 427

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  803 VQDLEAHLQKSAGELQqalakldllhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLlTKQVVEMETHKKHVCEELDA 882
Cdd:pfam15921  428 VQRLEALLKAMKSECQ--------------------GQMERQMAAIQGKNESLEKVSSL-TAQLESTKEMLRKVVEELTA 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  883 QRAQVQQLERQRSEL----EEKVRSLaqlqdsQLKNSTVEKEQARQSLMEKENIILQMREEQAK----EIEILKQTLSSK 954
Cdd:pfam15921  487 KKMTLESSERTVSDLtaslQEKERAI------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqtECEALKLQMAEK 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  955 EESISILHEEyetkfknqekrMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ----------KEKQFNAQI-- 1022
Cdd:pfam15921  561 DKVIEILRQQ-----------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdaKIRELEARVsd 629

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1023 LEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVieaweKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIV 1102
Cdd:pfam15921  630 LELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNEL-----NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSA 704

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1103 QSEKEElTKEVARLKEAVSGQDVALA-GLQGQLEQKSAVIVSL----------------------------SERESQLQS 1153
Cdd:pfam15921  705 QSELEQ-TRNTLKSMEGSDGHAMKVAmGMQKQITAKRGQIDALqskiqfleeamtnankekhflkeeknklSQELSTVAT 783

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198995 1154 QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE 1219
Cdd:pfam15921  784 EKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 197-993 1.54e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 1.54e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  197 LRRMERSLSSYRgKYSELVTAFQTLQREKKKLQGILS----QSQDKSLRRISELREELQMDQQAKKHLQDEFDACLEEKD 272
Cdd:TIGR02168  195 LNELERQLKSLE-RQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  273 QYISVLQTQVSLLKQRLQNgpmnvdapkplppgeLQAEVHG-DTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRC 351
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYA---------------LANEISRlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  352 KETIgshKEQCALLLSEKEALQEQLDERLQELEKMKGMVitETKRQMLETLE----LKEDEIAQLRSHIKQMTTQGEELR 427
Cdd:TIGR02168  339 LAEL---EEKLEELKEELESLEAELEELEAELEELESRL--EELEEQLETLRskvaQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  428 EQKEKsERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQK 507
Cdd:TIGR02168  414 DRRER-LQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  508 LhaeeLASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQkkAILTESEN---KLQELGQ 584
Cdd:TIGR02168  493 S----LERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQ--AVVVENLNaakKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  585 EAEAYRTRILELETSLEKSLQESKTQSehlavhleAEKNKHNKELTALAEQHRTEVEGLQQQ--QDSLWTERLQS-LSQQ 661
Cdd:TIGR02168  567 QNELGRVTFLPLDSIKGTEIQGNDREI--------LKNIEGFLGVAKDLVKFDPKLRKALSYllGGVLVVDDLDNaLELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  662 HQAAVEEL---REKYQQEKDALLKEKESLFQAHIQDmNEKTLEKLDKKQMELES----VSSELSEALRARDQLAEELSVL 734
Cdd:TIGR02168  639 KKLRPGYRivtLDGDLVRPGGVITGGSAKTNSSILE-RRREIEELEEKIEELEEkiaeLEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  735 RGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEkaLKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSA 814
Cdd:TIGR02168  718 RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE--LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  815 GELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQR 894
Cdd:TIGR02168  796 EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  895 SELEEKVRSLAQ---LQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAK---EIEILKQTLSSKEESISilhEEYETK 968
Cdd:TIGR02168  876 EALLNERASLEEalaLLRSELEELSEELRELESKRSELRRELEELREKLAQlelRLEGLEVRIDNLQERLS---EEYSLT 952

                          810       820
                   ....*....|....*....|....*
gi 1907198995  969 FKNQEKRMEKIKQKAKEMQETKKKL 993
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL 977
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1023-1717 1.79e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 1.79e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1023 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1097
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1098 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1177
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1178 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1257
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1258 SRDKAD----AILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1333
Cdd:TIGR02168  420 QQEIEEllkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1334 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1403
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1404 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1459
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1460 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1523
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1524 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1590
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1591 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1670
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198995 1671 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1493-2161 1.88e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.88e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1493 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1572
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1573 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1652
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1653 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1732
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1733 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1809
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1810 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1862
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1863 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1925
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1926 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 2005
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2006 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2085
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2086 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2160
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907198995 2161 A 2161
Cdd:TIGR02168  910 R 910
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1534-2101 2.68e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 2.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1534 DLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHV 1613
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1614 SSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQryAKDTENRLS 1693
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA--AAELAAQLE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1694 ELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRR 1773
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1774 LEQGEGEARPSQPEAQHRALSGKLDCTRARQLED--HVLIGCLPEELEEKMKCSLIVSQPMGEETGNNtgvkqnwasVVD 1851
Cdd:COG1196    484 EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglRGLAGAVAVLIGVEAAYEAALEAALAAALQNI---------VVE 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1852 SVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQS 1931
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1932 NVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 2011
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2012 LMREFNTQLAQKEQELERTVQETIDKAQEVEAEL-------------LESHQEETQQLHRKIAEK-------EDDLRRTA 2071
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLeeealeelpeppdLEELERELERLEREIEALgpvnllaIEEYEELE 794

                          570       580       590
                   ....*....|....*....|....*....|
gi 1907198995 2072 RRYeeildareEEMTGKVTDLQTQLEELQK 2101
Cdd:COG1196    795 ERY--------DFLSEQREDLEEARETLEE 816
PTZ00121 PTZ00121
MAEBL; Provisional
 332-802 3.14e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.85  E-value: 3.14e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  332 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQ 411
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE 1422

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  412 LRSHIKQMTtQGEELREQKEKSERAafEELEKALSTAQKTEDAQRRMkmemDEQMKAVERASEEERLRLQHELSRVRQEA 491
Cdd:PTZ00121  1423 AKKKAEEKK-KADEAKKKAEEAKKA--DEAKKKAEEAKKAEEAKKKA----EEAKKADEAKKKAEEAKKADEAKKKAEEA 1495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  492 ---ASMAKNSEEQVAALQKLHAEELASKEQELSRRLEARErelQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQK 568
Cdd:PTZ00121  1496 kkkADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK---ADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA 1572

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  569 KAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQD 648
Cdd:PTZ00121  1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL 1652

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  649 SLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLA 728
Cdd:PTZ00121  1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKA 1732

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198995  729 EELSvlRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDElsrlgaLLDERDEHLRERQAR 802
Cdd:PTZ00121  1733 EEAK--KEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE------ELDEEDEKRRMEVDK 1798
PTZ00121 PTZ00121
MAEBL; Provisional
 1444-2160 4.78e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 4.78e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1444 SKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEME 1522
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1523 VRKSKMEKKEcdlETALKTQTAR-VVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVRE 1601
Cdd:PTZ00121  1163 ARKAEEARKA---EDAKKAEAARkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1602 AE----ETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQkiaAIRKQLLSQM 1677
Cdd:PTZ00121  1240 EEakkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE---AKKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1678 EEKTQRYAKDTENRLSELSAQLKEREKQvhslEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERL 1757
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1758 CMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETG 1837
Cdd:PTZ00121  1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1838 NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1917
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1918 dRPEENSQSHEIQSnvgtVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-EKLKQ 1996
Cdd:PTZ00121  1553 -KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1997 EQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE---AELLESHQEETQQLHRKIAEKEDDLRRTA-- 2071
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEel 1707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2072 -------RRYEEILDAREEEMTGKVTDLQTQLEElQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELR 2144
Cdd:PTZ00121  1708 kkkeaeeKKKAEELKKAEEENKIKAEEAKKEAEE-DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                          730
                   ....*....|....*.
gi 1907198995 2145 EQVHNLEDRLKRYEKN 2160
Cdd:PTZ00121  1787 EEDEKRRMEVDKKIKD 1802
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1289-1717 1.41e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1289 QVSELEAQLTQLTEEQRTLKSSFQQVTNQL---EEKEKQIKTMKADIEGL-------LTEKEALQQEGGQQRQAASEKES 1358
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLretiaetEREREELAEEVRDLRERLEELEE 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1359 CITQLKKELA---ENINAVTLLREELSEKKSEIA-SLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQ 1434
Cdd:PRK02224   294 ERDDLLAEAGlddADAEAVEARREELEDRDEELRdRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1435 ELSLKVDAlSKEKMSALE-QVDHWSNKFS---EWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLlKEDLDRQ 1510
Cdd:PRK02224   374 EAREAVED-RREEIEELEeEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1511 NKKFECLK-----------GEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQrKKEVESLNETLKNYNQQRDTEHS 1579
Cdd:PRK02224   452 GKCPECGQpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1580 GLVQRLQHLEEL----------GEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNsSVKSRDGELKALEDKLE 1649
Cdd:PRK02224   531 TIEEKRERAEELreraaeleaeAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIE 609

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198995 1650 LESAAKVELKRKAEQKiaaiRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:PRK02224   610 RLREKREALAELNDER----RERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2186-2229 3.58e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.45  E-value: 3.58e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907198995  2186 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2229
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1189-1717 1.66e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1189 RVSELTGQVQAAEK--ELQSCKSLHELSKKSLEDKSLNLK-SLLEELASQLDSRCERTKALLEAKTNEL------VCTSR 1259
Cdd:COG1196    201 QLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELeelrleLEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1260 DKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKssfqqvtNQLEEKEKQIKTMKADIEGLLTEK 1339
Cdd:COG1196    281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1340 EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISpsdKAEAISALS 1419
Cdd:COG1196    354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1420 KQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQStiKDLQAQLDVKATDAREKEEQ 1499
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1500 ICLLKEDLDRQNKKFECLKGEMEVRKSkmekkecdLETALktQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT--- 1576
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAA--------YEAAL--EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflp 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1577 ----EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGEL-KALEDKLELE 1651
Cdd:COG1196    579 ldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLReVTLEGEGGSA 658

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198995 1652 SAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 352-685 3.05e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.43  E-value: 3.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  352 KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQmletlelkedeiAQLRSHIKQMTTQGEELREQKE 431
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQ------------AEMDRQAAIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  432 KSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKaVERASEEERLRLQHELSR-VRQEAASMAKNSEEQVAALQKLHA 510
Cdd:pfam17380  349 ELERIRQEERKRELERIRQEEIAMEISRMRELERLQ-MERQQKNERVRQELEAARkVKILEEERQRKIQQQKVEMEQIRA 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  511 EELASKEQELSRRLEARERELqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKlQELGQEAEAYR 590
Cdd:pfam17380  428 EQEEARQREVRRLEEERAREM-ERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRR-KILEKELEERK 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  591 TRILELETslEKSLQESKTQSEHLAVHLEAEKNKHNKELTalAEQHRTEVEGLQQQQDSLWTERlqslsqQHQAAVEELR 670
Cdd:pfam17380  506 QAMIEEER--KRKLLEKEMEERQKAIYEEERRREAEEERR--KQQEMEERRRIQEQMRKATEER------SRLEAMERER 575

                          330
                   ....*....|....*
gi 1907198995  671 EKYQQEKDALLKEKE 685
Cdd:pfam17380  576 EMMRQIVESEKARAE 590
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1037-1717 3.81e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 3.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1037 VSRLEENQRQQIESLtgahQRKLDDVIEAWEKK---LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEV 1113
Cdd:pfam15921   76 IERVLEEYSHQVKDL----QRRLNESNELHEKQkfyLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1114 ARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLR---- 1189
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILReldt 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1190 -VSELTGQVQAAEKELQSCKSlhelskksledkslNLKSLLEELASQLDSRCERTKALLEAKTN---ELVCTSRDKADAI 1265
Cdd:pfam15921  232 eISYLKGRIFPVEDQLEALKS--------------ESQNKIELLLQQHQDRIEQLISEHEVEITgltEKASSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1266 LARLSQCQRHTATVGEALLRrmgQVSELEAQLTQLTEEQRTLKSSFQqvtNQLEEKEKQIKTMKADIEGLLTEKEALQQE 1345
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSELREAKRMYE---DKIEELEKQLVLANSELTEARTERDQFSQE 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1346 GG------QQRQAASEKESCITQLKKELAENI------NAVTL--LREELSEKKSEIASLSKQL----SDLGAQLESSIS 1407
Cdd:pfam15921  372 SGnlddqlQKLLADLHKREKELSLEKEQNKRLwdrdtgNSITIdhLRRELDDRNMEVQRLEALLkamkSECQGQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1408 P----SDKAEAISALSKQHEEQELQLQAQLQELSLKVDALS-------------KEKMSALEQVDHWSNKFS---EWKKK 1467
Cdd:pfam15921  452 AiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLEssertvsdltaslQEKERAIEATNAEITKLRsrvDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1468 AQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNK---KFECLKGEMEVRKSKMEKKECDLETALK---- 1540
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQefki 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1541 ---TQTARVVELE----DCVTQRKKEVESLNETL---KNYNQQRDTEHSGLVQRLQHLEELGEEKD-------NKVREAE 1603
Cdd:pfam15921  612 lkdKKDAKIRELEarvsDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEvlkrnfrNKSEEME 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1604 ETVLRLREHVSSLEAELGTVKKELEHVNSS--------------VKSRDGELKALEDKLELESAAKVELKRKaeqkiaai 1669
Cdd:pfam15921  692 TTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgmqkqITAKRGQIDALQSKIQFLEEAMTNANKE-------- 763

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198995 1670 rKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:pfam15921  764 -KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2187-2226 1.56e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.88  E-value: 1.56e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907198995 2187 TEFEYLRKVMFEYMMGRET---KTMAKVITTVLKFPDDQAQKI 2226
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1480-2159 4.63e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 45.73  E-value: 4.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1480 KDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV--RKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1557
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEeeKEKKLQEEELKLLAKEEEELKSELLKLERRKVDD 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1558 KEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSR 1637
Cdd:pfam02463  313 EEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1638 DGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQmEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:pfam02463  393 KEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEI-LEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1718 SSPHPEVPAVSRSMQSVAASPEQEAPDSQDCThkACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKL 1797
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKES--KARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1798 DCTRAR-QLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELES 1876
Cdd:pfam02463  550 IVEVSAtADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGIL 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1877 DLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK 1956
Cdd:pfam02463  630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1957 LSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNtqlaQKEQELERTVQETID 2036
Cdd:pfam02463  710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELS----LKEKELAEEREKTEK 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2037 KAQEVEAELLESHQEETqqlhrkIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDS 2116
Cdd:pfam02463  786 LKVEEEKEEKLKAQEEE------LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL 859

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|...
gi 1907198995 2117 VTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEK 2159
Cdd:pfam02463  860 EEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEL 902
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 606-850 2.12e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  606 ESKTQSEHLAVHLE---AEKNKHNKELTALAEQHRTEVEGlQQQQDSLWTERLQSLSQQHQAaveeLREKYQQEKDALLK 682
Cdd:NF012221  1539 ESSQQADAVSKHAKqddAAQNALADKERAEADRQRLEQEK-QQQLAAISGSQSQLESTDQNA----LETNGQAQRDAILE 1613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  683 EKESlFQAHIQDMNeKTLEKLDkkqmELESVSSELSEalRARDQLAEE-LSVLRGDADKMKQALEAELEEQRRHH---QR 758
Cdd:NF012221  1614 ESRA-VTKELTTLA-QGLDALD----SQATYAGESGD--QWRNPFAGGlLDRVQEQLDDAKKISGKQLADAKQRHvdnQQ 1685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  759 EVGSISEQQELTVRRAEKalkdelSRLGALLDERDEHlreRQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 838
Cdd:NF012221  1686 KVKDAVAKSEAGVAQGEQ------NQANAEQDIDDAK---ADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                          250
                   ....*....|..
gi 1907198995  839 GAyEEQLAQMQQ 850
Cdd:NF012221  1757 AA-ENKANQAQA 1767
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1937-2047 6.05e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 6.05e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  1937 DGLRSDLESKLTGAERDKQKLSKE-------VARLQKELRALRREHQQeLDILKRECEQEAEEKLKQEQEDLElkhtSTL 2009
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKElellnsiKPKLRDRKDALEEELRQ-LKQLEDELEDCDPTELDRAKEKLK----KLL 217

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 1907198995  2010 KQLMREFN--TQLAQKEQELERTVQETIDKAQEVEAELLE 2047
Cdd:smart00787  218 QEIMIKVKklEELEEELQELESKIEDLTNKKSELNTEIAE 257
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 697-1303 1.87e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.87e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  697 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 774
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  775 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 854
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  855 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 934
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  935 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 1013
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1014 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1089
Cdd:COG1196    487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1090 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1169
Cdd:COG1196    567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1170 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1249
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198995 1250 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1303
Cdd:COG1196    720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 697-1403 3.03e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.52  E-value: 3.03e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  697 EKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRGDADKMkQALEAELEEQRRHHQREVGSISEQQELTVRRAEK 776
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  777 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 855
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  856 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ----RSELEEKVRSLAQLQDsQLKNSTVEKEQA---RQSLME 928
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEledlRAELEEVDKEFAETRD-ELKDYREKLEKLkreINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  929 KENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA---KLKKELE 1005
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1006 NTVLELSQKEKQ---------FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 1076
Cdd:TIGR02169  487 KLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1077 LRDKHA--------EQMEEKEQGLGELRQK------VRIVQSEKEELTKEVARLKEAVSGQDVALA----------GLQG 1132
Cdd:TIGR02169  567 LKRRKAgratflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAArrlmgkyrmvTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1133 QLEQKSAVIVSLSERESQLQS-------QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1205
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1206 SCKSLHELSK----------KSLEDKSLNLKSLLEELASQLDSRcERTKALLEAKTNELvctsrdKADAILARLSQCQRH 1275
Cdd:TIGR02169  727 QLEQEEEKLKerleeleedlSSLEQEIENVKSELKELEARIEEL-EEDLHKLEEALNDL------EARLSHSRIPEIQAE 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1276 TATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASE 1355
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198995 1356 KESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLE 1403
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 574-1411 1.52e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 1.52e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  574 ESENKLQElgqeAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALA---EQHRTEVEGLQQQQDSL 650
Cdd:TIGR02168  176 ETERKLER----TRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVlrlEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  651 WTER--LQSLSQQHQAAVEELReKYQQEKDALLKEKESLFQAHIQDMNEKTL------EKLDKKQMELESVSSELSEALR 722
Cdd:TIGR02168  252 EEELeeLTAELQELEEKLEELR-LEVSELEEEIEELQKELYALANEISRLEQqkqilrERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  723 ARDQLAEELsvlrgdadkmkQALEAELEEQRRHHQREVGSISEQQELTV--RRAEKALKDELSRLGALLDERDEHLRERQ 800
Cdd:TIGR02168  331 KLDELAEEL-----------AELEEKLEELKEELESLEAELEELEAELEelESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  801 ARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAR-----EQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKH 875
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  876 VCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNS----------TVEKEQARQ---SLMEKENIILQMREEQAK 942
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSgilgvlseliSVDEGYEAAieaALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  943 E-IEILKQTLSSKE---ESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL----------------LDQEAKLKK 1002
Cdd:TIGR02168  560 KaIAFLKQNELGRVtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1003 ELENTVLELSQKEKQFNAQILeMAQANSAGISDTVSRLEE--NQRQQIESLTGAhQRKLDDVIEAWEKKLSQQAAELRDK 1080
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGGV-ITGGSAKTNSSILERRREieELEEKIEELEEK-IAELEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1081 HAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEA 1160
Cdd:TIGR02168  718 RKE-LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1161 DLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckslhELSKKSLEDKSLNLKSLLEELASqldsrc 1240
Cdd:TIGR02168  797 ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL-------EDLEEQIEELSEDIESLAAEIEE------ 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1241 ertkalLEAKTNELvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEE 1320
Cdd:TIGR02168  864 ------LEELIEEL----ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1321 KEKQIKTMKADI--EGLLTEKEALQQEGGQQRQAASEKEScITQLKKELAE----NINAVtllrEELSEKKSEIASLSKQ 1394
Cdd:TIGR02168  934 LEVRIDNLQERLseEYSLTLEEAEALENKIEDDEEEARRR-LKRLENKIKElgpvNLAAI----EEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|
gi 1907198995 1395 LSDLG---AQLESSISPSDK 1411
Cdd:TIGR02168 1009 KEDLTeakETLEEAIEEIDR 1028
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 461-1052 4.12e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.54  E-value: 4.12e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  461 EMDEQMKAVERASE--EERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQE----- 533
Cdd:COG1196    197 ELERQLEPLERQAEkaERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEElrlel 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  534 -QMRIALEKSRSEYLKLTQEKEQ--QESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQ 610
Cdd:COG1196    277 eELELELEEAQAEEYELLAELARleQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  611 SEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLfqa 690
Cdd:COG1196    357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL--- 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  691 hiqdmnektLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadkmkqALEAELEEQRRHHQREVGSISEQQELT 770
Cdd:COG1196    434 ---------EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL--------EEAALLEAALAELLEELAEAAARLLLL 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  771 VRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQ 850
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  851 KVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKE 930
Cdd:COG1196    577 LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGG 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  931 NIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLE 1010
Cdd:COG1196    657 SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE 736

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1907198995 1011 LSQKEKQFNAQILEMAQANSAGISDtvsrlEENQRQQIESLT 1052
Cdd:COG1196    737 LLEELLEEEELLEEEALEELPEPPD-----LEELERELERLE 773
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 393-1180 4.23e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 4.23e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  393 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER-----AAFEELEKALSTAQKTEDAQRRMKMEMDEQMK 467
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERykelkAELRELELALLVLRLEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  468 AVERASEEERLR-LQHELSRVRQEAASMAKNSEEQVAALQKLhaeelaskeQELSRRLEARERELQEQMRIALEKsrSEY 546
Cdd:TIGR02168  252 EEELEELTAELQeLEEKLEELRLEVSELEEEIEELQKELYAL---------ANEISRLEQQKQILRERLANLERQ--LEE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  547 LKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHN 626
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  627 KELTALaeqhRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkekeslfqahiqdmnEKTLEKLDKK 706
Cdd:TIGR02168  400 NEIERL----EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL----------------EELQEELERL 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  707 QMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRR-----HHQRE----VGSISEQ----------- 766
Cdd:TIGR02168  460 EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGvkallKNQSGlsgiLGVLSELisvdegyeaai 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  767 --------QELTVRRAEKALKD---------------ELSRL-GALLDERDEHLRERQARVQDLEAHLQKSAGE------ 816
Cdd:TIGR02168  540 eaalggrlQAVVVENLNAAKKAiaflkqnelgrvtflPLDSIkGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkals 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  817 -----------LQQALAKLDLLHSEQSAAREQA------GAYEEQLAQMQQKVLDLETEKSLLTKQVVEMEthkkhvcEE 879
Cdd:TIGR02168  620 yllggvlvvddLDNALELAKKLRPGYRIVTLDGdlvrpgGVITGGSAKTNSSILERRREIEELEEKIEELE-------EK 692

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  880 LDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEESIs 959
Cdd:TIGR02168  693 IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAEIEELEERL- 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  960 ilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEkqfnaQILEMAQANSAGISDTVSR 1039
Cdd:TIGR02168  771 ---EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-----ERLESLERRIAATERRLED 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1040 LE---ENQRQQIESLTGAhQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARL 1116
Cdd:TIGR02168  843 LEeqiEELSEDIESLAAE-IEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198995 1117 KEAVSGQDVALAGLQGQLEQksaVIVSLSERESQLQSQVEKLEADLGCSLSEklsLQEELAELK 1180
Cdd:TIGR02168  921 REKLAQLELRLEGLEVRIDN---LQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 364-898 3.89e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 88.46  E-value: 3.89e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  364 LLLSEKEALQEQLDERLQELEKmkgmvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQ---------KEKSE 434
Cdd:COG1196    229 LLLLKLRELEAELEELEAELEE-----LEAELEELEAELAELEAELEELRLELEELELELEEAQAEeyellaelaRLEQD 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  435 RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELsrvrQEAASMAKNSEEQVAALQKLHAEELA 514
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL----EEAEAELAEAEEALLEAEAELAEAEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  515 SKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRIL 594
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  595 ELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEG-------LQQQQDSLWTE--RLQSLSQQHQAA 665
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLegvkaalLLAGLRGLAGAvaVLIGVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  666 VEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQAL 745
Cdd:COG1196    540 LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  746 EAELEEQRRHHQREVGSI----SEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL 821
Cdd:COG1196    620 DTLLGRTLVAARLEAALRravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  822 AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQ----VVEMETHKKHVCEELDAQRAQVQQLERQRSEL 897
Cdd:COG1196    700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEeeelLEEEALEELPEPPDLEELERELERLEREIEAL 779


                   .
gi 1907198995  898 E 898
Cdd:COG1196    780 G 780
PTZ00121 PTZ00121
MAEBL; Provisional
 368-1088 1.00e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 87.50  E-value: 1.00e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  368 EKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAA--FEELEKA- 444
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAArkAEEVRKAe 1191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  445 -LSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAEELASKEQELSRR 523
Cdd:PTZ00121  1192 eLRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAA 1271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  524 LEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKailTESENKLQELGQEAEAYRTRILEletsLEKS 603
Cdd:PTZ00121  1272 IKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKA---DEAKKKAEEAKKKADAAKKKAEE----AKKA 1344

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  604 LQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKE 683
Cdd:PTZ00121  1345 AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK 1424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  684 KESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSI 763
Cdd:PTZ00121  1425 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKK 1504

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  764 SEQQEltvRRAEKALKDELSRLGALLDERDEHLRERQARvqdlEAHLQKSAGELQQAlakLDLLHSEQSAAREQAGAYEE 843
Cdd:PTZ00121  1505 AAEAK---KKADEAKKAEEAKKADEAKKAEEAKKADEAK----KAEEKKKADELKKA---EELKKAEEKKKAEEAKKAEE 1574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  844 QLAQMQQKVLDL-ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKvrslaQLQDSQLKNSTVEKEQA 922
Cdd:PTZ00121  1575 DKNMALRKAEEAkKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK-----KKVEQLKKKEAEEKKKA 1649

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  923 RQSLMEKENIILQMREEQAKEIEILKQTLSSKEEsisilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 1002
Cdd:PTZ00121  1650 EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA------EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1003 ELENTVLELSQKEKQFNAQILEMAQAnsagisdtvsRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHA 1082
Cdd:PTZ00121  1724 AEEENKIKAEEAKKEAEEDKKKAEEA----------KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRR 1793


                   ....*.
gi 1907198995 1083 EQMEEK 1088
Cdd:PTZ00121  1794 MEVDKK 1799
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 765-1711 1.73e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 1.73e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  765 EQQELTVRRAEKALKDeLSRLGALLDERDEHLR--ERQAR--VQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGA 840
Cdd:TIGR02168  172 ERRKETERKLERTREN-LDRLEDILNELERQLKslERQAEkaERYKELKAELRELELALLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  841 YEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQrseLEEKVRSLAQLQDSQLKNSTVEKE 920
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ---KQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  921 QARQSLMEKENiiLQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQEtkkklldQEAKL 1000
Cdd:TIGR02168  328 LESKLDELAEE--LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------QIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1001 KKELENTVLELSQKEkqfnaqilEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKkLSQQAAELRdk 1080
Cdd:TIGR02168  399 NNEIERLEARLERLE--------DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELER-LEEALEELR-- 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1081 haEQMEEKEQGLGELRQKVRIVQSEKEELtkevARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSER---ESQLQSQVEK 1157
Cdd:TIGR02168  468 --EELEEAEQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEA 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1158 -LEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTG----QVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEEL 1232
Cdd:TIGR02168  542 aLGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1233 ASQLdsrcertkalleaktneLVCTSRDKADAILARLSQCQRHTATVGEaLLRRMGQVSELEAQLTQLTEEQRtlkssfq 1312
Cdd:TIGR02168  622 LGGV-----------------LVVDDLDNALELAKKLRPGYRIVTLDGD-LVRPGGVITGGSAKTNSSILERR------- 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1313 qvtNQLEEKEKQIKTMKADIEGLLTEKEALqqeggqqRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLS 1392
Cdd:TIGR02168  677 ---REIEELEEKIEELEEKIAELEKALAEL-------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1393 KQLSDLGAQLEssispsdKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRL 1472
Cdd:TIGR02168  747 ERIAQLSKELT-------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1473 AQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLdrqnkkfECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEdc 1552
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDI-------ESLAAEIEELEELIEELESELEALLNERASLEEALA-- 890

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1553 vtQRKKEVESLNETLKNYNQQRDTehsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLeaelgtVKKELEHVNS 1632
Cdd:TIGR02168  891 --LLRSELEELSEELRELESKRSE----LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE------YSLTLEEAEA 958

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198995 1633 SVKSRDGELKALEDKLelesaakvelkRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLED 1711
Cdd:TIGR02168  959 LENKIEDDEEEARRRL-----------KRLENKIKELGPVNLAAIEE-----YEELKERYDFLTAQKEDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 884-1716 7.38e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.34  E-value: 7.38e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  884 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQaKEIEILKQTLSSKEESISILHE 963
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEEL-EELTAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  964 EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQansagisdtvsrleen 1043
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE---------------- 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1044 QRQQIESLTGAHQRKLDDVIEAWEKklsQQAAELRdkhaeqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQ 1123
Cdd:TIGR02168  342 LEEKLEELKEELESLEAELEELEAE---LEELESR------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1124 DVALAGLQGQLEQKSAVIVSLSEREsqLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKE 1203
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1204 LQSCKSLHEL------SKKSLEDKSLNLKSLLEELASQLDSRCERTKAL---LEAKTNELVCTSRDKADAILARLSQCQR 1274
Cdd:TIGR02168  491 LDSLERLQENlegfseGVKALLKNQSGLSGILGVLSELISVDEGYEAAIeaaLGGRLQAVVVENLNAAKKAIAFLKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1275 HTATVGEALLRRmgqvselEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQ--- 1351
Cdd:TIGR02168  571 GRVTFLPLDSIK-------GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlrp 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1352 --------------------AASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDK 1411
Cdd:TIGR02168  644 gyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1412 AEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKAT 1491
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1492 DAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYN 1571
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1572 QQRdtehsglvQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgelkaledklele 1651
Cdd:TIGR02168  884 SLE--------EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE----------------------- 932

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198995 1652 saakvelkrKAEQKIAairkQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNL 1716
Cdd:TIGR02168  933 ---------GLEVRID----NLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 218-874 1.02e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.83  E-value: 1.02e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  218 FQTLQREKKKLQGILSqsqdksLRRISELREELQMDQQAKKHLQDEFDACLEEKDQyisvLQTQVSLLKQRLQngpmnvd 297
Cdd:COG1196    215 YRELKEELKELEAELL------LLKLRELEAELEELEAELEELEAELEELEAELAE----LEAELEELRLELE------- 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  298 apkplppgELQAEVHGDTEKMEGVGEPVGGGtsAKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLD 377
Cdd:COG1196    278 --------ELELELEEAQAEEYELLAELARL--EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  378 ERLQELekmkgmvitETKRQMLETLELKEDEIAQLRshikqmttqgEELREQKEKSERAAFEELEKALSTAQKTEDAQRR 457
Cdd:COG1196    348 EAEEEL---------EEAEAELAEAEEALLEAEAEL----------AEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  458 MKMEMDEQmkavERASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRI 537
Cdd:COG1196    409 EEALLERL----ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  538 ALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVH 617
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIE 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  618 LEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNE 697
Cdd:COG1196    565 YLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  698 KTLEKL-------DKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVgsISEQQELT 770
Cdd:COG1196    645 RLREVTlegeggsAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE--ERLEEELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  771 VRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQ 850
Cdd:COG1196    723 EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVNLLAIEEYEELEERYDFLSE 802

                          650       660
                   ....*....|....*....|....
gi 1907198995  851 KVLDLETEKSLLTKQVVEMETHKK 874
Cdd:COG1196    803 QREDLEEARETLEEAIEEIDRETR 826
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 412-1219 7.12e-15

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 80.93  E-value: 7.12e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  412 LRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDaqrrMKMEMDEQMKAVERASE-EERLRLQ-----HELS 485
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQE----MQMERDAMADIRRRESQsQEDLRNQlqntvHELE 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  486 RVRQEAASMAKNSEEQVAALQKLhaeelaskeqelsrrLEARERELQEqmrialekSRSEYLKLTQEKEQQESLALEELE 565
Cdd:pfam15921  156 AAKCLKEDMLEDSNTQIEQLRKM---------------MLSHEGVLQE--------IRSILVDFEEASGKKIYEHDSMST 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  566 LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaekNKHNKELTALAEQHRTEVEGLQQ 645
Cdd:pfam15921  213 MHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLL-------QQHQDRIEQLISEHEVEITGLTE 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  646 QQDSLWTERlQSLSQQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRA 723
Cdd:pfam15921  286 KASSARSQA-NSIQSQLEIIQEQARNQNSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTE 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  724 RDQLAEElsvlRGDADKMKQALEAELeeqrrhHQREvgsiseqQELTVRRAE-KALKDELSRLGALLDERDEHLRERQAR 802
Cdd:pfam15921  365 RDQFSQE----SGNLDDQLQKLLADL------HKRE-------KELSLEKEQnKRLWDRDTGNSITIDHLRRELDDRNME 427

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  803 VQDLEAHLQKSAGELQqalakldllhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLlTKQVVEMETHKKHVCEELDA 882
Cdd:pfam15921  428 VQRLEALLKAMKSECQ--------------------GQMERQMAAIQGKNESLEKVSSL-TAQLESTKEMLRKVVEELTA 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  883 QRAQVQQLERQRSEL----EEKVRSLaqlqdsQLKNSTVEKEQARQSLMEKENIILQMREEQAK----EIEILKQTLSSK 954
Cdd:pfam15921  487 KKMTLESSERTVSDLtaslQEKERAI------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqtECEALKLQMAEK 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  955 EESISILHEEyetkfknqekrMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ----------KEKQFNAQI-- 1022
Cdd:pfam15921  561 DKVIEILRQQ-----------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdaKIRELEARVsd 629

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1023 LEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVieaweKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIV 1102
Cdd:pfam15921  630 LELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNEL-----NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSA 704

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1103 QSEKEElTKEVARLKEAVSGQDVALA-GLQGQLEQKSAVIVSL----------------------------SERESQLQS 1153
Cdd:pfam15921  705 QSELEQ-TRNTLKSMEGSDGHAMKVAmGMQKQITAKRGQIDALqskiqfleeamtnankekhflkeeknklSQELSTVAT 783

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198995 1154 QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE 1219
Cdd:pfam15921  784 EKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 402-1121 1.19e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.19e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  402 LELKEDEIAQLRSHIKQMTTQGEELREQKEKSE------RAAFEELEKALSTAQKTEDAQR-------RMKMEMDEQMKA 468
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEekleelRLEVSELEEEIEELQKELYALAneisrleQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  469 VERASEEERLRLQHELSRvRQEAASMAKNSEEQVAALQKLHA------EELASKEQELSRRLEARERELQE------QMR 536
Cdd:TIGR02168  314 LERQLEELEAQLEELESK-LDELAEELAELEEKLEELKEELEsleaelEELEAELEELESRLEELEEQLETlrskvaQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  537 IALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE------KSLQESKTQ 610
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELErleealEELREELEE 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  611 SEHLAVHLEAEKNKHNKELTALaEQHRTEVEGLQQQQDSLWTERLQsLSQQHQAAVE--ELREKYQQEKDALLKE----- 683
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG-LSGILGVLSEliSVDEGYEAAIEAALGGrlqav 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  684 ----------------KESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGD-------ADK 740
Cdd:TIGR02168  551 vvenlnaakkaiaflkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvVDD 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  741 MKQALEaeleeQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALldERDEHLRERQARVQDLEAHLQKSAGELQQA 820
Cdd:TIGR02168  631 LDNALE-----LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSIL--ERRREIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  821 LAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEK 900
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  901 VRSLAQLQDSQLKNSTVEKEQ-------------ARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYEt 967
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREAldelraeltllneEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE- 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  968 kfkNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNA--QILEMAQANSAGISDTVSRLEENQR 1045
Cdd:TIGR02168  863 ---ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSElrRELEELREKLAQLELRLEGLEVRID 939

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1046 QQIESLTGAHQRKLDDVIEAWEKKLSQQaAELRDKhAEQMEEKEQGLG-----------ELRQKVRIVQSEKEELTKEVA 1114
Cdd:TIGR02168  940 NLQERLSEEYSLTLEEAEALENKIEDDE-EEARRR-LKRLENKIKELGpvnlaaieeyeELKERYDFLTAQKEDLTEAKE 1017


                   ....*..
gi 1907198995 1115 RLKEAVS 1121
Cdd:TIGR02168 1018 TLEEAIE 1024
PTZ00121 PTZ00121
MAEBL; Provisional
 428-1099 6.84e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 78.26  E-value: 6.84e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  428 EQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKNSEEQVAA--- 504
Cdd:PTZ00121  1216 EARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAdea 1295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  505 ---LQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQE 581
Cdd:PTZ00121  1296 kkaEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE 1375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  582 LGQEAEAYRTRILELETS--LEKSLQESKTQSEHLAVHLE-----------AEKNKHNKELTALAEQHRTEVEGLQQQQD 648
Cdd:PTZ00121  1376 AKKKADAAKKKAEEKKKAdeAKKKAEEDKKKADELKKAAAakkkadeakkkAEEKKKADEAKKKAEEAKKADEAKKKAEE 1455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  649 SLWTERLQSLSQQHQAAvEELREKYQQEKDA-LLKEKESLFQAHIQDMNEKTLEKL---DKKQMELESVSSELSEALRAR 724
Cdd:PTZ00121  1456 AKKAEEAKKKAEEAKKA-DEAKKKAEEAKKAdEAKKKAEEAKKKADEAKKAAEAKKkadEAKKAEEAKKADEAKKAEEAK 1534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  725 DQLAEELSVLRGDADKMKQALEAELEEQRRHHQrEVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRE-----R 799
Cdd:PTZ00121  1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAE-EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMkaeeaK 1613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  800 QARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEE 879
Cdd:PTZ00121  1614 KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEA 1693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  880 LDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENI-ILQMREEQAKEIEILKQTLSSKEESI 958
Cdd:PTZ00121  1694 LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAeEAKKDEEEKKKIAHLKKEEEKKAEEI 1773

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  959 SI---------LHEEYETKFKNQEKRMEKIKQKAKEMQE----------TKKKLLDQEAKLKKELENTVLELSQKEKQ-- 1017
Cdd:PTZ00121  1774 RKekeavieeeLDEEDEKRRMEVDKKIKDIFDNFANIIEggkegnlvinDSKEMEDSAIKEVADSKNMQLEEADAFEKhk 1853

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1018 FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDV-IEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELR 1096
Cdd:PTZ00121  1854 FNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIeREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETR 1933


                   ...
gi 1907198995 1097 QKV 1099
Cdd:PTZ00121  1934 EEI 1936
PTZ00121 PTZ00121
MAEBL; Provisional
 405-1125 1.01e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.49  E-value: 1.01e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  405 KEDEIAQLRSHIKQMTTQGE-ELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHE 483
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEAfGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  484 LSRVRQ-------EAASMAKNSEEQVAALQKLHAEELASKEQ----ELSRRLEaRERELQEQMRIALEKSRSEYLKLTQE 552
Cdd:PTZ00121  1157 ARKAEDarkaeeaRKAEDAKKAEAARKAEEVRKAEELRKAEDarkaEAARKAE-EERKAEEARKAEDAKKAEAVKKAEEA 1235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  553 KEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSlqESKTQSEHLAvhlEAEKNKHNKELTAL 632
Cdd:PTZ00121  1236 KKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKA--EEKKKADEAK---KAEEKKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  633 AEQHRTEVEGLQQQQDS-LWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELE 711
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAkKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  712 SVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDE 791
Cdd:PTZ00121  1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  792 RDEHLRERQARVQDLEaHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMET 871
Cdd:PTZ00121  1471 KADEAKKKAEEAKKAD-EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD 1549

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  872 HKKHVCEELDAQraQVQQLERQRSELEEKVRSLAQLQDSQlknstvEKEQAR-QSLMEKENIILQMREEQAK--EIEILK 948
Cdd:PTZ00121  1550 ELKKAEELKKAE--EKKKAEEAKKAEEDKNMALRKAEEAK------KAEEARiEEVMKLYEEEKKMKAEEAKkaEEAKIK 1621

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  949 QTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQA 1028
Cdd:PTZ00121  1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA 1701

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1029 NSAgisDTVSRLEENQRQQIESLTGAHQRKLDDVIEAwekklsQQAAELRDKHAEQMEEKEqglgELRQKVRIVQSEKEE 1108
Cdd:PTZ00121  1702 KKA---EELKKKEAEEKKKAEELKKAEEENKIKAEEA------KKEAEEDKKKAEEAKKDE----EEKKKIAHLKKEEEK 1768

                          730
                   ....*....|....*..
gi 1907198995 1109 LTKEVARLKEAVSGQDV 1125
Cdd:PTZ00121  1769 KAEEIRKEKEAVIEEEL 1785
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 197-993 1.54e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 1.54e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  197 LRRMERSLSSYRgKYSELVTAFQTLQREKKKLQGILS----QSQDKSLRRISELREELQMDQQAKKHLQDEFDACLEEKD 272
Cdd:TIGR02168  195 LNELERQLKSLE-RQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  273 QYISVLQTQVSLLKQRLQNgpmnvdapkplppgeLQAEVHG-DTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRC 351
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYA---------------LANEISRlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  352 KETIgshKEQCALLLSEKEALQEQLDERLQELEKMKGMVitETKRQMLETLE----LKEDEIAQLRSHIKQMTTQGEELR 427
Cdd:TIGR02168  339 LAEL---EEKLEELKEELESLEAELEELEAELEELESRL--EELEEQLETLRskvaQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  428 EQKEKsERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQK 507
Cdd:TIGR02168  414 DRRER-LQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  508 LhaeeLASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQkkAILTESEN---KLQELGQ 584
Cdd:TIGR02168  493 S----LERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQ--AVVVENLNaakKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  585 EAEAYRTRILELETSLEKSLQESKTQSehlavhleAEKNKHNKELTALAEQHRTEVEGLQQQ--QDSLWTERLQS-LSQQ 661
Cdd:TIGR02168  567 QNELGRVTFLPLDSIKGTEIQGNDREI--------LKNIEGFLGVAKDLVKFDPKLRKALSYllGGVLVVDDLDNaLELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  662 HQAAVEEL---REKYQQEKDALLKEKESLFQAHIQDmNEKTLEKLDKKQMELES----VSSELSEALRARDQLAEELSVL 734
Cdd:TIGR02168  639 KKLRPGYRivtLDGDLVRPGGVITGGSAKTNSSILE-RRREIEELEEKIEELEEkiaeLEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  735 RGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEkaLKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSA 814
Cdd:TIGR02168  718 RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE--LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  815 GELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQR 894
Cdd:TIGR02168  796 EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  895 SELEEKVRSLAQ---LQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAK---EIEILKQTLSSKEESISilhEEYETK 968
Cdd:TIGR02168  876 EALLNERASLEEalaLLRSELEELSEELRELESKRSELRRELEELREKLAQlelRLEGLEVRIDNLQERLS---EEYSLT 952

                          810       820
                   ....*....|....*....|....*
gi 1907198995  969 FKNQEKRMEKIKQKAKEMQETKKKL 993
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL 977
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1023-1717 1.79e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 1.79e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1023 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1097
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1098 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1177
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1178 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1257
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1258 SRDKAD----AILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1333
Cdd:TIGR02168  420 QQEIEEllkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1334 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1403
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1404 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1459
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1460 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1523
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1524 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1590
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1591 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1670
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198995 1671 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 365-1118 1.95e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.26  E-value: 1.95e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  365 LLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKA 444
Cdd:TIGR02169  235 LERQKEAIERQLASLEEELEKLT------------EEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAE 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  445 LSTAQKTEDAQRRMKMEMDEQmkavERASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAE--ELASKEQELSR 522
Cdd:TIGR02169  303 IASLERSIAEKERELEDAEER----LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEleDLRAELEEVDK 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  523 RL-EARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE 601
Cdd:TIGR02169  379 EFaETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  602 KSLQE-SKTQSEHLAvhLEAEKNKHNKELTALAEQH----------RTEVEGLQQQQDSLWTER---------LQSLSQQ 661
Cdd:TIGR02169  459 QLAADlSKYEQELYD--LKEEYDRVEKELSKLQRELaeaeaqarasEERVRGGRAVEEVLKASIqgvhgtvaqLGSVGER 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  662 HQAAVEEL-----------REKYQQEKDALLKEKEsLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEE 730
Cdd:TIGR02169  537 YATAIEVAagnrlnnvvveDDAVAKEAIELLKRRK-AGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPA 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  731 LSVLRGDA---DKMKQA-----------LEAELEEQ--------RRHHQREVGSISEQQEL-TVRRAEKALKDELSRLGA 787
Cdd:TIGR02169  616 FKYVFGDTlvvEDIEAArrlmgkyrmvtLEGELFEKsgamtggsRAPRGGILFSRSEPAELqRLRERLEGLKRELSSLQS 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  788 LLDERDEHLRERQARVQDLEAHLQKSAGELQQalakldlLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVV 867
Cdd:TIGR02169  696 ELRRIENRLDELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  868 EMETHKKHVCEELDA-----QRAQVQQLERQRSELEEKVRSL-AQLQ--DSQLKNSTVEKEQARQSLMEKENIILQM--- 936
Cdd:TIGR02169  769 ELEEDLHKLEEALNDlearlSHSRIPEIQAELSKLEEEVSRIeARLReiEQKLNRLTLEKEYLEKEIQELQEQRIDLkeq 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  937 REEQAKEIEILKQTLSSKEESIsilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEK 1016
Cdd:TIGR02169  849 IKSIEKEIENLNGKKEELEEEL----EELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA 924

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1017 QfnaqiLEMAQANSAGISDTVSRLEEnqrqqiESLTGAHQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELR 1096
Cdd:TIGR02169  925 K-----LEALEEELSEIEDPKGEDEE------IPEEELSLEDVQAELQRVEEEI-RALEPVNMLAIQEYEEVLKRLDELK 992

                          810       820
                   ....*....|....*....|..
gi 1907198995 1097 QKVRIVQSEKEELTKEVARLKE 1118
Cdd:TIGR02169  993 EKRAKLEEERKAILERIEEYEK 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 393-1220 3.11e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.87  E-value: 3.11e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  393 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER----------AAFEELEKALSTAQKTEDAQRRMKMEM 462
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqallkekreYEGYELLKEKEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  463 DEQMKAVERASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKlHAEELASKEQELSRRLEARERELQE--------Q 534
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKE-KIGELEAEIASLERSIAEKERELEDaeerlaklE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  535 MRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKsLQESKTQSEHL 614
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK-LKREINELKRE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  615 AVHLEAEKnkhnKELTALAEQHRTEVEGLQQQQDSLWTERLQSlsqqhQAAVEELREKYQQEKDALLKEKESLFQahiqd 694
Cdd:TIGR02169  408 LDRLQEEL----QRLSEELADLNAAIAGIEAKINELEEEKEDK-----ALEIKKQEWKLEQLAADLSKYEQELYD----- 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  695 mnekTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadkmkqALEAELEEQRR--HHQ-REVGSISEQQELTV 771
Cdd:TIGR02169  474 ----LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGR--------AVEEVLKASIQgvHGTvAQLGSVGERYATAI 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  772 RRAEKAlkdelsRLGALLDERD-------EHLRERQA-----------RVQDLEAHLQKSAGELQQALAKLD-------- 825
Cdd:TIGR02169  542 EVAAGN------RLNNVVVEDDavakeaiELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEfdpkyepa 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  826 --------LLHSEQSAAREQAGAYeeQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSEL 897
Cdd:TIGR02169  616 fkyvfgdtLVVEDIEAARRLMGKY--RMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  898 EEKVRSlaqlQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQtlssKEESISILHEEYEtkfkNQEKRME 977
Cdd:TIGR02169  694 QSELRR----IENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE----LEEDLSSLEQEIE----NVKSELK 761

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  978 KIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFnaqILEMAQANSAGISDTVSRLEENQrQQIESLTGAHQR 1057
Cdd:TIGR02169  762 ELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSK---LEEEVSRIEARLREIEQKLNRLT-LEKEYLEKEIQE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1058 KLDDVIEAWEKKLSQQAAELRDKhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQK 1137
Cdd:TIGR02169  838 LQEQRIDLKEQIKSIEKEIENLN--GKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1138 SAVIVSLSERESQLQSQVEKLEADLGCSLSE----------KLSLQEELAELKLLADKSQLRVSELTgQVQAAEKELQSC 1207
Cdd:TIGR02169  916 RKRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsledvQAELQRVEEEIRALEPVNMLAIQEYE-EVLKRLDELKEK 994

                          890
                   ....*....|...
gi 1907198995 1208 KSLHELSKKSLED 1220
Cdd:TIGR02169  995 RAKLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1493-2161 1.88e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.88e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1493 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1572
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1573 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1652
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1653 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1732
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1733 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1809
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1810 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1862
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1863 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1925
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1926 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 2005
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2006 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2085
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2086 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2160
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907198995 2161 A 2161
Cdd:TIGR02168  910 R 910
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 866-1717 2.03e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 2.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  866 VVEMETHKKHVCEELDAQRaqvQQLERQRSELEEKVRSLAQLQDsqlknstvEKEQARQSLmekeniILQMREEQAKEIE 945
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVE---ENIERLDLIIDEKRQQLERLRR--------EREKAERYQ------ALLKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  946 ILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQIlEM 1025
Cdd:TIGR02169  228 LLKE-KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEI-AS 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1026 AQANSAGISDTVSRLEENQRQQIESLtgahqRKLDDVIEAWEKKLSQQAAElRDKHAEQMEEKEQGLGELRQKVRIVQSE 1105
Cdd:TIGR02169  306 LERSIAEKERELEDAEERLAKLEAEI-----DKLLAEIEELEREIEEERKR-RDKLTEEYAELKEELEDLRAELEEVDKE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1106 KEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEElaelklladk 1185
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE---------- 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1186 sqlrVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCtsRDKADAI 1265
Cdd:TIGR02169  450 ----IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVL--KASIQGV 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1266 LARLSQC----QRHTATVGEALLRRMGQV----SELEAQLTQLTEEQRTLKSSFQQVTN-QLEEKEKQIKTMKADIE--- 1333
Cdd:TIGR02169  524 HGTVAQLgsvgERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLNKmRDERRDLSILSEDGVIGfav 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1334 --------------------GLLTEKEALQQEGGQQRQAA-----SEKESCITQLKKELAENINAVTLLREELSEKKSEI 1388
Cdd:TIGR02169  604 dlvefdpkyepafkyvfgdtLVVEDIEAARRLMGKYRMVTlegelFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERL 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1389 ASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKA 1468
Cdd:TIGR02169  684 EGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1469 QSRLAQHQSTIKDLQAQL-DVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVV 1547
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1548 ELEDCVTQRKKEVESLN----------ETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLE 1617
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNgkkeeleeelEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1618 AELGTVKKELEHVNSSVKSrdgelkALEDKLELESAAKVELKRKA-EQKIAAIRKQLLSQMEEktqryAKDTENRLSELS 1696
Cdd:TIGR02169  924 AKLEALEEELSEIEDPKGE------DEEIPEEELSLEDVQAELQRvEEEIRALEPVNMLAIQE-----YEEVLKRLDELK 992

                          890       900
                   ....*....|....*....|.
gi 1907198995 1697 AQLKEREKQVHSLEDKLKNLE 1717
Cdd:TIGR02169  993 EKRAKLEEERKAILERIEEYE 1013
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 516-1348 3.04e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 3.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  516 KEQELSRRLEARERElqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAiLTESENKLQELGQEAEAYRTRILE 595
Cdd:TIGR02169  172 KEKALEELEEVEENI--ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYE-GYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  596 LETSLEKS---LQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREK 672
Cdd:TIGR02169  249 LEEELEKLteeISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--ERSIAEKERELEDAEERLAK 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  673 YQQEKDALLKEKESL---------FQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQ 743
Cdd:TIGR02169  327 LEAEIDKLLAEIEELereieeerkRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  744 ALEAELEEQRRHHQRevgsiseqqeltVRRAEKALKDELSRLGALlderdehlrerQARVQDLEAHLQKSAGELQQALAK 823
Cdd:TIGR02169  407 ELDRLQEELQRLSEE------------LADLNAAIAGIEAKINEL-----------EEEKEDKALEIKKQEWKLEQLAAD 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  824 LDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKslltKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEK-VR 902
Cdd:TIGR02169  464 LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA----RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyAT 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  903 SLAQLQDSQLKNSTVEKEQARQSLMEkenIILQMREEQAKEIEILKqtLSSKEESISILHEE----YETKFKNQEKRMEK 978
Cdd:TIGR02169  540 AIEVAAGNRLNNVVVEDDAVAKEAIE---LLKRRKAGRATFLPLNK--MRDERRDLSILSEDgvigFAVDLVEFDPKYEP 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  979 IKQKA------KEMQETKKKLLDQEAKLKKELEntvlelsqkekqfnaqILEMAQANSAGiSDTVSRLEENQRQQIESLt 1052
Cdd:TIGR02169  615 AFKYVfgdtlvVEDIEAARRLMGKYRMVTLEGE----------------LFEKSGAMTGG-SRAPRGGILFSRSEPAEL- 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1053 gahqRKLDDVIEAWEKKLSQQAAELRDKHAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQG 1132
Cdd:TIGR02169  677 ----QRLRERLEGLKRELSSLQSELRRIENR-LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1133 QLEQKSAVIVSLSERESQLQSQVEKLEADLGcSLSEKLSlQEELAELKLLADKSQLRVSELTGQVQAAEKELQSckslHE 1212
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALN-DLEARLS-HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNR----LT 825

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1213 LSKKSLEDKSLNLKSLLEELASQLDSRCERTKALleaktnelvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSE 1292
Cdd:TIGR02169  826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL------------NGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198995 1293 LEAQLTQLTEEQRTLKSsfqqvtnQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQ 1348
Cdd:TIGR02169  894 LEAQLRELERKIEELEA-------QIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 189-897 7.66e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 7.66e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  189 SREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSQdkslRRISELREELQMDQQAKKHLQDEF---D 265
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA----NEISRLEQQKQILRERLANLERQLeelE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  266 ACLEEKDQYISVLQTQVSLLKQRLQNGPMNVDapkplppgELQAEVhgDTEKMEGVGEPVGGGTSAKTLEMLQQRV---K 342
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELE--------SLEAEL--EELEAELEELESRLEELEEQLETLRSKVaqlE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  343 RQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQ 422
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEE 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  423 GEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQM--------------------KAVERASEEerlRLQH 482
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSglsgilgvlselisvdegyeAAIEAALGG---RLQA 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  483 ELSR----VRQEAASMAKNSEEQVA----------ALQKLHAEELASKEQELSRRLEARERELQ---------------E 533
Cdd:TIGR02168  550 VVVEnlnaAKKAIAFLKQNELGRVTflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  534 QMRIALE---KSRSEYLKLTQEKEQQESL-ALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE--KSLQES 607
Cdd:TIGR02168  630 DLDNALElakKLRPGYRIVTLDGDLVRPGgVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAelRKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  608 KTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQslSQQHQAAVEELREKYQQEKDALLKEKESL 687
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE--LEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  688 fQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQ 767
Cdd:TIGR02168  788 -EAQIEQLKEE-LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  768 EltvrrAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQ 847
Cdd:TIGR02168  866 E-----LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907198995  848 MQQKVldleTEKSLLTKQvvEMETHKKHVCEELDAQRAQVQQLERQRSEL 897
Cdd:TIGR02168  941 LQERL----SEEYSLTLE--EAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1534-2101 2.68e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 2.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1534 DLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHV 1613
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1614 SSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQryAKDTENRLS 1693
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA--AAELAAQLE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1694 ELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRR 1773
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1774 LEQGEGEARPSQPEAQHRALSGKLDCTRARQLED--HVLIGCLPEELEEKMKCSLIVSQPMGEETGNNtgvkqnwasVVD 1851
Cdd:COG1196    484 EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglRGLAGAVAVLIGVEAAYEAALEAALAAALQNI---------VVE 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1852 SVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQS 1931
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1932 NVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 2011
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2012 LMREFNTQLAQKEQELERTVQETIDKAQEVEAEL-------------LESHQEETQQLHRKIAEK-------EDDLRRTA 2071
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLeeealeelpeppdLEELERELERLEREIEALgpvnllaIEEYEELE 794

                          570       580       590
                   ....*....|....*....|....*....|
gi 1907198995 2072 RRYeeildareEEMTGKVTDLQTQLEELQK 2101
Cdd:COG1196    795 ERY--------DFLSEQREDLEEARETLEE 816
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1854-2158 2.73e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 2.73e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1854 QKTLQEKELTCQALEQRVKELESDLVRErgahrlEVEKLTLKYEKSQSSQQEMdgENKCVEVLEDRPEENSQSHEIQSNV 1933
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEA------ELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1934 GTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQEldilkreceQEAEEKLKQEQEDLELKHTSTLKQLM 2013
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL---------EEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2014 REFNTQLAQKEQELERtvQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQ 2093
Cdd:COG1196    362 EAEEALLEAEAELAEA--EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198995 2094 TQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2158
Cdd:COG1196    440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1465-2156 6.59e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 6.59e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1465 KKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKM---EKKECDLETALKT 1541
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLanlERQLEELEAQLEE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1542 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHsglvQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELG 1621
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELE----AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1622 TVKKELEHVNSSVKSRDGELKALEDKLEL----ESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKdTENRLSELSA 1697
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEaelkELQAELEELEEELEELQEELERLEEALEELREELEE-AEQALDAAER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1698 QLKEREKQVHSLEDKLKNLE-------------SSPHPEVPAVSR------------------SMQSVAASPEQEAPDSQ 1746
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEgfsegvkallknqSGLSGILGVLSElisvdegyeaaieaalggRLQAVVVENLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1747 DCTHKACKERLCMLQRRLSEKEKL----LRRLEQGEGEARP-----SQPEAQHRALSGKLDCTR-----------ARQLE 1806
Cdd:TIGR02168  563 AFLKQNELGRVTFLPLDSIKGTEIqgndREILKNIEGFLGVakdlvKFDPKLRKALSYLLGGVLvvddldnalelAKKLR 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1807 DHVLIGCLPEEL---------EEKMKCSLIVSQpmGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESD 1877
Cdd:TIGR02168  643 PGYRIVTLDGDLvrpggvitgGSAKTNSSILER--RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1878 LVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLED-RPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK 1956
Cdd:TIGR02168  721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAeIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1957 LSKEVARLQKELRALRREHQQeldilkreceqeAEEKLKQEQEDLELKhtstlKQLMREFNTQLAQKEQELERTVQEtID 2036
Cdd:TIGR02168  801 LREALDELRAELTLLNEEAAN------------LRERLESLERRIAAT-----ERRLEDLEEQIEELSEDIESLAAE-IE 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2037 KAQEVEAELLESHQEETQQLhrkiaEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKds 2116
Cdd:TIGR02168  863 ELEELIEELESELEALLNER-----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE-- 935

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198995 2117 VTILELQTQLAQK--------TTLISDSKLKEQELREQVHNLEDRLKR 2156
Cdd:TIGR02168  936 VRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIKE 983
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 534-1220 6.80e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 64.86  E-value: 6.80e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  534 QMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKaiLTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEH 613
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFG--YKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNG 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  614 LAVHLEAEKNKHNKELTALAEQHR------TEVEGLQQQQDSLWTERLQSLSQQHqAAVEELREKYQQEKDALLKEKESL 687
Cdd:pfam12128  309 ELSAADAAVAKDRSELEALEDQHGafldadIETAAADQEQLPSWQSELENLEERL-KALTGKHQDVTAKYNRRRSKIKEQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  688 FQAHIQDMNEKTLEKLDKKQMELESVSSELsEALRA--RDQLAEELSVLRGDADKMKQAL------------EAELEEQR 753
Cdd:pfam12128  388 NNRDIAGIKDKLAKIREARDRQLAVAEDDL-QALESelREQLEAGKLEFNEEEYRLKSRLgelklrlnqataTPELLLQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  754 RHHQREVGSISEQQElTVRRAEKALKDELSRLGALLDERDEHLRERQARVQdleahlqksagELQQALAKLDLLHSEQSA 833
Cdd:pfam12128  467 ENFDERIERAREEQE-AANAEVERLQSELRQARKRRDQASEALRQASRRLE-----------ERQSALDELELQLFPQAG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  834 A-----REQAGAYEEQLAQMQQKVLDLETEkslLTKQVVEMETHKKHVCE--ELDAQRAQV-------QQLERQRSELEE 899
Cdd:pfam12128  535 TllhflRKEAPDWEQSIGKVISPELLHRTD---LDPEVWDGSVGGELNLYgvKLDLKRIDVpewaaseEELRERLDKAEE 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  900 KV---RSLAQLQDSQLKnstvekeQARQSLmekeniilqmrEEQAKEIEILKQTLSSKEESISILHEEYET-KFKNQEKR 975
Cdd:pfam12128  612 ALqsaREKQAAAEEQLV-------QANGEL-----------EKASREETFARTALKNARLDLRRLFDEKQSeKDKKNKAL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  976 MEKIKQKAKEMQ--ETKKKLLDQEAKL-KKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLT 1052
Cdd:pfam12128  674 AERKDSANERLNslEAQLKQLDKKHQAwLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALE 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1053 GAHQRKLD--DVIEAWEKKLSQQAAELRDKhAEQMEEKEQGLGELRQKVRivqsekEELTKEVARLKEAVSGQDVALAGL 1130
Cdd:pfam12128  754 TWYKRDLAslGVDPDVIAKLKREIRTLERK-IERIAVRRQEVLRYFDWYQ------ETWLQRRPRLATQLSNIERAISEL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1131 QGQLEQKSA-VIVSLSERESQLQSQvEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSeLTGQVQAAEKELQSCKS 1209
Cdd:pfam12128  827 QQQLARLIAdTKLRRAKLEMERKAS-EKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGS-IGERLAQLEDLKLKRDY 904

                          730
                   ....*....|.
gi 1907198995 1210 LHELSKKSLED 1220
Cdd:pfam12128  905 LSESVKKYVEH 915
PTZ00121 PTZ00121
MAEBL; Provisional
 332-802 3.14e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.85  E-value: 3.14e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  332 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQ 411
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE 1422

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  412 LRSHIKQMTtQGEELREQKEKSERAafEELEKALSTAQKTEDAQRRMkmemDEQMKAVERASEEERLRLQHELSRVRQEA 491
Cdd:PTZ00121  1423 AKKKAEEKK-KADEAKKKAEEAKKA--DEAKKKAEEAKKAEEAKKKA----EEAKKADEAKKKAEEAKKADEAKKKAEEA 1495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  492 ---ASMAKNSEEQVAALQKLHAEELASKEQELSRRLEARErelQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQK 568
Cdd:PTZ00121  1496 kkkADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK---ADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA 1572

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  569 KAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQD 648
Cdd:PTZ00121  1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL 1652

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  649 SLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLA 728
Cdd:PTZ00121  1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKA 1732

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198995  729 EELSvlRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDElsrlgaLLDERDEHLRERQAR 802
Cdd:PTZ00121  1733 EEAK--KEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE------ELDEEDEKRRMEVDK 1798
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 837-1719 3.80e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 62.37  E-value: 3.80e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  837 QAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRseleeKVRSLAQLQDSQLKNST 916
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSR-----EIVKSYENELDPLKNRL 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  917 VEKEQARQSLMEKENII-------LQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQET 989
Cdd:TIGR00606  255 KEIEHNLSKIMKLDNEIkalksrkKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  990 KKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVieaweKK 1069
Cdd:TIGR00606  335 RRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEA-----KT 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1070 LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSEres 1149
Cdd:TIGR00606  410 AAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERE--- 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1150 qlQSQVEKlEADLGCSLSEKLSLQEELAELklladksqlrvseltgqvqaaekELQSCKSLHELSKKSLEDKSLNLKSLL 1229
Cdd:TIGR00606  487 --LSKAEK-NSLTETLKKEVKSLQNEKADL-----------------------DRKLRKLDQEMEQLNHHTTTRTQMEML 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1230 EELASQLDSRCERTKAlleaktnelvctsrdKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKS 1309
Cdd:TIGR00606  541 TKDKMDKDEQIRKIKS---------------RHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQ 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1310 SFQQVTNQLEEKEKQIKTMKADI------EGLLTEKEALQQE---GGQQRQAASEKESCITQLKKELAENINAVTLLREE 1380
Cdd:TIGR00606  606 NKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEiekSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1381 LSEKKSEIASLSKQLSDLgaqlesSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNK 1460
Cdd:TIGR00606  686 VFQTEAELQEFISDLQSK------LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1461 FSEWKKKAQSRLAQHQSTIKDLQAQLDVKA--TDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLEta 1538
Cdd:TIGR00606  760 IQRLKNDIEEQETLLGTIMPEEESAKVCLTdvTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHE-- 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1539 LKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRlQHLEELGEEKDNKVREAEETVLRLREHVSSLEA 1618
Cdd:TIGR00606  838 LDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR-QQFEEQLVELSTEVQSLIREIKDAKEQDSPLET 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1619 elgTVKKELEHVNSSVKSRDGELKALEDKLElesaakvELKRKAEQKIAAiRKQLLSQMEEKTQRYAKDTENRLSELSAQ 1698
Cdd:TIGR00606  917 ---FLEKDQQEKEELISSKETSNKKAQDKVN-------DIKEKVKNIHGY-MKDIENKIQDGKDDYLKQKETELNTVNAQ 985

                          890       900
                   ....*....|....*....|.
gi 1907198995 1699 LKEREKQVHSLEDKLKNLESS 1719
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQD 1006
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 364-1185 4.73e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 4.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  364 LLLSEKEALQEQLDERLQELEKmkgmvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEK 443
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLAS-----LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEA 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  444 ALSTAQKTEDAQRRMKMEMDEQmkavERASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAE--ELASKEQELS 521
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEER----LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEleDLRAELEEVD 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  522 RRL-EARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSL 600
Cdd:TIGR02169  378 KEFaETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  601 EKSLQE-SKTQSEHLAvhLEAEKNKHNKELTALAEQH----------RTEVEGLQQQQDSLWTER---------LQSLSQ 660
Cdd:TIGR02169  458 EQLAADlSKYEQELYD--LKEEYDRVEKELSKLQRELaeaeaqarasEERVRGGRAVEEVLKASIqgvhgtvaqLGSVGE 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  661 QHQAAVEEL-----------REKYQQEKDALLKEKEsLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAE 729
Cdd:TIGR02169  536 RYATAIEVAagnrlnnvvveDDAVAKEAIELLKRRK-AGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEP 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  730 ELSVLRGDA---DKMKQA-----------LEAELEEQ--------RRHHQREVGSISEQQEL-TVRRAEKALKDELSRLG 786
Cdd:TIGR02169  615 AFKYVFGDTlvvEDIEAArrlmgkyrmvtLEGELFEKsgamtggsRAPRGGILFSRSEPAELqRLRERLEGLKRELSSLQ 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  787 ALLDERDEHLRERQARVQDLEAHLQKSAGELQQalakldlLHSEQSAAREQAGAYEEQLAQMQQKVLDLEtekslltkqv 866
Cdd:TIGR02169  695 SELRRIENRLDELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLSSLEQEIENVK---------- 757

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  867 vemethkkhvcEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNSTVEKEQArqslmekeniilqmrEEQAKEIE 945
Cdd:TIGR02169  758 -----------SELKELEARIEELEEDLHKLEEALNDLeARLSHSRIPEIQAELSKL---------------EEEVSRIE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  946 ILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFnaqilem 1025
Cdd:TIGR02169  812 ARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRL------- 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1026 aqansAGISDTVSRLEENQRQQiesltgahqrklddvieawEKKLSQQAAELrdkhaeqmEEKEQGLGELRQKVRIVQSE 1105
Cdd:TIGR02169  885 -----GDLKKERDELEAQLREL-------------------ERKIEELEAQI--------EKKRKRLSELKAKLEALEEE 932

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1106 KEELTKEVARLKEaVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADK 1185
Cdd:TIGR02169  933 LSEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEE 1011
PTZ00121 PTZ00121
MAEBL; Provisional
 1444-2160 4.78e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 4.78e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1444 SKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEME 1522
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1523 VRKSKMEKKEcdlETALKTQTAR-VVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVRE 1601
Cdd:PTZ00121  1163 ARKAEEARKA---EDAKKAEAARkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1602 AE----ETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQkiaAIRKQLLSQM 1677
Cdd:PTZ00121  1240 EEakkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE---AKKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1678 EEKTQRYAKDTENRLSELSAQLKEREKQvhslEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERL 1757
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1758 CMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETG 1837
Cdd:PTZ00121  1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1838 NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1917
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1918 dRPEENSQSHEIQSnvgtVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-EKLKQ 1996
Cdd:PTZ00121  1553 -KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1997 EQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE---AELLESHQEETQQLHRKIAEKEDDLRRTA-- 2071
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEel 1707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2072 -------RRYEEILDAREEEMTGKVTDLQTQLEElQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELR 2144
Cdd:PTZ00121  1708 kkkeaeeKKKAEELKKAEEENKIKAEEAKKEAEE-DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                          730
                   ....*....|....*.
gi 1907198995 2145 EQVHNLEDRLKRYEKN 2160
Cdd:PTZ00121  1787 EEDEKRRMEVDKKIKD 1802
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 541-1007 5.26e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.57  E-value: 5.26e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  541 KSRSEYLKLTQEKEQQESLALEELE--LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQE-SKTQSEHLAVH 617
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTeiKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNiDKIKNKLLKLE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  618 LE----AEKNKHNKELTA----LAEQHRTEVEGLQQQQDSL---------WTERLQSLSQQHQAAVEELREKYQQ--EKD 678
Cdd:TIGR04523  201 LLlsnlKKKIQKNKSLESqiseLKKQNNQLKDNIEKKQQEInektteisnTQTQLNQLKDEQNKIKKQLSEKQKEleQNN 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  679 ALLKEKESLFQA-----------HIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKmKQALEA 747
Cdd:TIGR04523  281 KKIKELEKQLNQlkseisdlnnqKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTN-SESENS 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  748 ELEEQRRHHQREVGSISEQQELTVRRAEKaLKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLL 827
Cdd:TIGR04523  360 EKQRELEEKQNEIEKLKKENQSYKQEIKN-LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  828 HSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQL 907
Cdd:TIGR04523  439 NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  908 QDSQLKNS---TVEKEQARQSLMEKENIILQMREEQAKEIeiLKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAK 984
Cdd:TIGR04523  519 ISSLKEKIeklESEKKEKESKISDLEDELNKDDFELKKEN--LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEK 596

                          490       500
                   ....*....|....*....|....*.
gi 1907198995  985 EMQETKKKLLDQEAK---LKKELENT 1007
Cdd:TIGR04523  597 EKKDLIKEIEEKEKKissLEKELEKA 622
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1292-2107 5.62e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 5.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1292 ELEAQLTQLteEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENI 1371
Cdd:TIGR02168  217 ELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1372 NAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSAL 1451
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1452 EQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQL-DVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEK 1530
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLeRLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1531 KECDLETALKTQTARVVELEDCVTQRKKEVESLN---ETLKNYNQQRDTEHSGLVQRLQHLEELGE---------EKDNK 1598
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEGVKALLKNQSGLSGilgvlseliSVDEG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1599 VREAEETVlrLREHVSSLEAElgTVKKELEHVNSSVKSRDGELKALEdkLELESAAKVELKRKAEQKIAAIRKQLLSQME 1678
Cdd:TIGR02168  535 YEAAIEAA--LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVTFLP--LDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1679 EKTQRYAKDTENRLS------------ELSAQLKEREKQVhSLEDKLknleSSPHPEVPAVSRSMQSVAASPEQEAPDSQ 1746
Cdd:TIGR02168  609 KFDPKLRKALSYLLGgvlvvddldnalELAKKLRPGYRIV-TLDGDL----VRPGGVITGGSAKTNSSILERRREIEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1747 DCThKACKERLCMLQRRLSEKEKLLRRLEQGEGEAR--PSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKC 1824
Cdd:TIGR02168  684 EKI-EELEEKIAELEKALAELRKELEELEEELEQLRkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1825 SLIVSQPMGEETGNNTGVKQNWASVVDSVQKtlqekeltcqaLEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQ 1904
Cdd:TIGR02168  763 IEELEERLEEAEEELAEAEAEIEELEAQIEQ-----------LKEELKALREALDELRAELTLLNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1905 EMDGENKCVEVLEDRPEENSQSHE-IQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALR---REHQQELD 1980
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIEsLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSeelRELESKRS 911

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1981 ILKRECE--QEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLaqkeQELERTVQETIDKAQEVEAElLESHQEETQQLHR 2058
Cdd:TIGR02168  912 ELRRELEelREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL----EEAEALENKIEDDEEEARRR-LKRLENKIKELGP 986

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1907198995 2059 KIAEKEDDLRRTARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRL 2107
Cdd:TIGR02168  987 VNLAAIEEYEELKERYDF-LTAQKEDLTEAKETLEEAIEEIDREARERF 1034
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 377-1226 6.11e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.53  E-value: 6.11e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  377 DERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKqmttqGEELREQKEKSERAAFEELEKALSTAQKTEDAQR 456
Cdd:pfam02463  153 ERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLE-----ELKLQELKLKEQAKKALEYYQLKEKLELEEEYLL 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  457 RMKMEMD--EQMKAVERASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQ 534
Cdd:pfam02463  228 YLDYLKLneERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLER 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  535 MRIALEKSRSEyLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHL 614
Cdd:pfam02463  308 RKVDDEEKLKE-SEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERL 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  615 AvhLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQqhQAAVEELREKYQQEKDALLKEKESLfQAHIQD 694
Cdd:pfam02463  387 S--SAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELE--ILEEEEESIELKQGKLTEEKEELEK-QELKLL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  695 MNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRA 774
Cdd:pfam02463  462 KDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  775 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQaLAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 854
Cdd:pfam02463  542 KVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPK-LKLPLKSIAVLEIDPILNLAQLDKATLEADEDDK 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  855 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQvqqlERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIIL 934
Cdd:pfam02463  621 RAKVVEGILKDTELTKLKESAKAKESGLRKGV----SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  935 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQK 1014
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1015 EKQFNAQILEMAQ--------ANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQME 1086
Cdd:pfam02463  777 AEEREKTEKLKVEeekeeklkAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEEL 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1087 EKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSL 1166
Cdd:pfam02463  857 ERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEE 936

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1167 SEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLK 1226
Cdd:pfam02463  937 PEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELE 996
PTZ00121 PTZ00121
MAEBL; Provisional
 1458-2118 6.26e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 6.26e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1458 SNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKME----KKE 1532
Cdd:PTZ00121  1169 ARKAEDAKKAEAARKAEEVRKAEELRKAEDArKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEakkaEEE 1248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1533 CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGE--EKDNKVREAEETVLRLR 1610
Cdd:PTZ00121  1249 RNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAK 1328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1611 EHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEqkiAAIRKQLLSQMEEKTQRYAKDTEN 1690
Cdd:PTZ00121  1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD---AAKKKAEEKKKADEAKKKAEEDKK 1405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1691 RLSELSAQlKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKL 1770
Cdd:PTZ00121  1406 KADELKKA-AAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK 1484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1771 LRRLEQGEGEARPSQPEAQHRAlSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVV 1850
Cdd:PTZ00121  1485 ADEAKKKAEEAKKKADEAKKAA-EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEK 1563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1851 DSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQ 1930
Cdd:PTZ00121  1564 KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1931 SNVGTVDGLRSDLESKLTGAERDKQKlSKEVARLQKELRALRREHQQELDILKRECEQ--EAEEKLKQEQEDLELKHTST 2008
Cdd:PTZ00121  1644 EEKKKAEELKKAEEENKIKAAEEAKK-AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEakKAEELKKKEAEEKKKAEELK 1722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2009 LKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGK 2088
Cdd:PTZ00121  1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802

                          650       660       670
                   ....*....|....*....|....*....|
gi 1907198995 2089 VTDLQTQLEELQKKYQQRLEQEESTKDSVT 2118
Cdd:PTZ00121  1803 IFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 966-1569 6.96e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.19  E-value: 6.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  966 ETKFKNQEKRMEKI----KQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEKQFNAQILEMAQANSAGISD-TVSRL 1040
Cdd:TIGR04523   32 DTEEKQLEKKLKTIknelKNKEKELKNLDKNLNKDEEK-INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDlSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1041 EENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAV 1120
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKE-LEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1121 SGQDVALAglqgQLEQKSAVIVSLSERESQLQSQVEKLEadlgcslseklslqEELAELKLLADKSQLRVSELTGQVQAA 1200
Cdd:TIGR04523  190 DKIKNKLL----KLELLLSNLKKKIQKNKSLESQISELK--------------KQNNQLKDNIEKKQQEINEKTTEISNT 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1201 EKELQSCKSLHELSKKSLEDKSLNL---KSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTA 1277
Cdd:TIGR04523  252 QTQLNQLKDEQNKIKKQLSEKQKELeqnNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQIS 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1278 TVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKE 1357
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKD 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1358 SCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLES-SISPSDKAEAISALSKQHEEQELQLQAQLQEL 1436
Cdd:TIGR04523  412 EQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNlDNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1437 SLKV---DALSKEKMSALEQVDHWSNKFSEWKKKAQ---SRLAQHQSTIKDLQAQLDVKATDAREKeeqicLLKEDLDRQ 1510
Cdd:TIGR04523  492 KSKEkelKKLNEEKKELEEKVKDLTKKISSLKEKIEkleSEKKEKESKISDLEDELNKDDFELKKE-----NLEKEIDEK 566

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198995 1511 NKKFECLKGEMEVRKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKN 1569
Cdd:TIGR04523  567 NKEIEELKQTQKSLKKKQEEKQelidqkekekKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 332-1137 7.48e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.53  E-value: 7.48e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  332 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQ 411
Cdd:pfam02463  227 LYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLE 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  412 LRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRrmkmemdeqmkAVERASEEERLRLQHELSRVRQEA 491
Cdd:pfam02463  307 RRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKR-----------EAEEEEEEELEKLQEKLEQLEEEL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  492 ASMAKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMriaLEKSRSEYLKLTQEKEQQESLALEELELQKKAI 571
Cdd:pfam02463  376 LAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLED---LLKEEKKEELEILEEEEESIELKQGKLTEEKEE 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  572 LTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLW 651
Cdd:pfam02463  453 LEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLG 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  652 TERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAE-E 730
Cdd:pfam02463  533 DLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKaT 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  731 LSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHL 810
Cdd:pfam02463  613 LEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  811 QKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQL 890
Cdd:pfam02463  693 EILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLK 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  891 ERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFK 970
Cdd:pfam02463  773 EKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLA 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  971 NQEKRMEKIKQKAKEmQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIES 1050
Cdd:pfam02463  853 EEELERLEEEITKEE-LLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILL 931

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1051 LTGAHQRKLDDVIEAWEKKLSQQAAELRDKhAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGL 1130
Cdd:pfam02463  932 KYEEEPEELLLEEADEKEKEENNKEEEEER-NKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRA 1010


                   ....*..
gi 1907198995 1131 QGQLEQK 1137
Cdd:pfam02463 1011 IIEETCQ 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1553-2158 1.04e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 1.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1553 VTQRKKEVESLNETLKNYNQQRDTehsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNS 1632
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEE----LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1633 SVKSRDGELKALEDKLELESAAKVELKRKAEQ--------------------KIAAIRKQLLSQMEEKTQRY------AK 1686
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAEleekleelkeelesleaeleELEAELEELESRLEELEEQLetlrskVA 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1687 DTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSE 1766
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1767 KEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV------------LIGCLPEELE--------------- 1819
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkallknqsglsgILGVLSELISvdegyeaaieaalgg 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1820 -----------------------EKMKCSLIV--------SQPMGEETGNNTGVKQNWASVVDSVQKTLQE--------- 1859
Cdd:TIGR02168  546 rlqavvvenlnaakkaiaflkqnELGRVTFLPldsikgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggv 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1860 ---KELTcQALEQRVKE--------LESDLVRERGAHRLEVEKLTLkyeKSQSSQQEMDGENKCVEVLEdrpeenSQSHE 1928
Cdd:TIGR02168  626 lvvDDLD-NALELAKKLrpgyrivtLDGDLVRPGGVITGGSAKTNS---SILERRREIEELEEKIEELE------EKIAE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1929 IQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTST 2008
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2009 LKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAEL------LESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDARE 2082
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELtllneeAANLRERLESLERRIAATERRLEDLEEQIEE-LSEDI 854

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198995 2083 EEMTGKVTDLQTQLEELQKKYQQRLEQEESTKdsVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2158
Cdd:TIGR02168  855 ESLAAEIEELEELIEELESELEALLNERASLE--EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1289-1719 1.09e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.42  E-value: 1.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1289 QVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELA 1368
Cdd:TIGR04523  219 QISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1369 ENINAVTllREELSEKKSEIASLSKQLSDLGAQLESSISP-SDKAEAISALSKQHEEQELQLQAQLQELSLKVDA---LS 1444
Cdd:TIGR04523  299 DLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIiSQLNEQISQLKKELTNSESENSEKQRELEEKQNEiekLK 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1445 KEKMSALEQVDHWSNKFSEWKKKAQsrlaQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVR 1524
Cdd:TIGR04523  377 KENQSYKQEIKNLESQINDLESKIQ----NQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1525 K---SKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKVRE 1601
Cdd:TIGR04523  453 EliiKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEK 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1602 AEETVLRLREHVSSLEAELGTVKKEL--EHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKiAAIRKQLLSQMEE 1679
Cdd:TIGR04523  529 LESEKKEKESKISDLEDELNKDDFELkkENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQK-EKEKKDLIKEIEE 607

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1907198995 1680 KTQryakdtenRLSELSAQLKEREKQVHSLEDKLKNLESS 1719
Cdd:TIGR04523  608 KEK--------KISSLEKELEKAKKENEKLSSIIKNIKSK 639
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
483-1007 1.30e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.70  E-value: 1.30e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  483 ELSRVRQEAASMaknsEEQVAALQKLhaEELASKEQELSRRLEARERELQeqmrialeksrseylKLTQEKEQQESLALE 562
Cdd:COG4913    236 DLERAHEALEDA----REQIELLEPI--RELAERYAAARERLAELEYLRA---------------ALRLWFAQRRLELLE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  563 ELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEG 642
Cdd:COG4913    295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLP 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  643 LQQQQDSLWteRLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHiqdmnektlEKLDKKQMELESVSSEL-SEAL 721
Cdd:COG4913    375 LPASAEEFA--ALRAEAAALLEALEEELEALEEALAEAEAALRDLRREL---------RELEAEIASLERRKSNIpARLL 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  722 RARDQLAEELSV-------------LRGDADKMKQALEAELEEQRR------HHQREVGSISEQQELTVR-RAEKALKDE 781
Cdd:COG4913    444 ALRDALAEALGLdeaelpfvgelieVRPEEERWRGAIERVLGGFALtllvppEHYAAALRWVNRLHLRGRlVYERVRTGL 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  782 LSRLGALLDER-----------------DEHLRERQARV-----QDLEAH--------LQKSAGEL-------------- 817
Cdd:COG4913    524 PDPERPRLDPDslagkldfkphpfrawlEAELGRRFDYVcvdspEELRRHpraitragQVKGNGTRhekddrrrirsryv 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  818 --QQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLtkqvvemETHKKHVCEELDAQ--RAQVQQLERQ 893
Cdd:COG4913    604 lgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-------QRLAEYSWDEIDVAsaEREIAELEAE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  894 RSELEEKVRSLAQLQD--SQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISI-LHEEYETKFK 970
Cdd:COG4913    677 LERLDASSDDLAALEEqlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFA 756

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1907198995  971 NQEKRmEKIKQKAKEMQETKKKLLDQEAKLKKELENT 1007
Cdd:COG4913    757 AALGD-AVERELRENLEERIDALRARLNRAEEELERA 792
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1289-1717 1.41e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1289 QVSELEAQLTQLTEEQRTLKSSFQQVTNQL---EEKEKQIKTMKADIEGL-------LTEKEALQQEGGQQRQAASEKES 1358
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLretiaetEREREELAEEVRDLRERLEELEE 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1359 CITQLKKELA---ENINAVTLLREELSEKKSEIA-SLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQ 1434
Cdd:PRK02224   294 ERDDLLAEAGlddADAEAVEARREELEDRDEELRdRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1435 ELSLKVDAlSKEKMSALE-QVDHWSNKFS---EWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLlKEDLDRQ 1510
Cdd:PRK02224   374 EAREAVED-RREEIEELEeEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1511 NKKFECLK-----------GEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQrKKEVESLNETLKNYNQQRDTEHS 1579
Cdd:PRK02224   452 GKCPECGQpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1580 GLVQRLQHLEEL----------GEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNsSVKSRDGELKALEDKLE 1649
Cdd:PRK02224   531 TIEEKRERAEELreraaeleaeAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIE 609

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198995 1650 LESAAKVELKRKAEQKiaaiRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:PRK02224   610 RLREKREALAELNDER----RERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
997-1401 1.48e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.48e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  997 EAKLKKELENTVLELSQKEKQFNAQIlemaqansagisdtvSRLEENQRQQIESLTgahqrKLDDVIEAWEKKLsqqaae 1076
Cdd:PRK02224   197 EEKEEKDLHERLNGLESELAELDEEI---------------ERYEEQREQARETRD-----EADEVLEEHEERR------ 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1077 lrdkhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1156
Cdd:PRK02224   251 ------EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1157 KLEADL-------GCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSL------ 1223
Cdd:PRK02224   325 ELRDRLeecrvaaQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdap 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1224 ----NLKSLLEELASQLD-----------------SRCERTKALLEA----------KTNELVCT---SRDKADAILARL 1269
Cdd:PRK02224   405 vdlgNAEDFLEELREERDelrereaeleatlrtarERVEEAEALLEAgkcpecgqpvEGSPHVETieeDRERVEELEAEL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1270 SQCQRHTATVgEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ 1349
Cdd:PRK02224   485 EDLEEEVEEV-EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198995 1350 RQAASEKESCITQLKKELAENINAVTLLR------EELSEKKSEIASLSKQLSDLGAQ 1401
Cdd:PRK02224   564 EEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAEL 621
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1554-2109 2.61e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1554 TQRKKEVESLNETLKNYNQQRDTEHsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEA--------ELGTVKK 1625
Cdd:COG4913    268 RERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELERLEARLDALREELDELEAqirgnggdRLEQLER 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1626 ELEHVNSSVKSRDGELKALEDKLelesaAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQ 1705
Cdd:COG4913    346 EIERLERELEERERRRARLEALL-----AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1706 VHSLEDKLKNLESSP---HPEVPAVSRSMQSVAASPEQEAP--------DSQDCTHKACKER------LCML--QRRLS- 1765
Cdd:COG4913    421 LRELEAEIASLERRKsniPARLLALRDALAEALGLDEAELPfvgelievRPEEERWRGAIERvlggfaLTLLvpPEHYAa 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1766 -----EKEKLLRRL---EQGEGEARPSQPEAQHRALSGKLD----------------------CTRARQLEDH---VLIG 1812
Cdd:COG4913    501 alrwvNRLHLRGRLvyeRVRTGLPDPERPRLDPDSLAGKLDfkphpfrawleaelgrrfdyvcVDSPEELRRHpraITRA 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1813 CL---PEELEEKmkcslivsqpmgeetGNNTGVKQNWASVVDSVQKtLQEKELTCQALEQRVKELESDLVRERGAHRLEV 1889
Cdd:COG4913    581 GQvkgNGTRHEK---------------DDRRRIRSRYVLGFDNRAK-LAALEAELAELEEELAEAEERLEALEAELDALQ 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1890 EKLTL--KYEKSQSSQQEMDGENKCVEVLEDRPEE----NSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVAR 1963
Cdd:COG4913    645 ERREAlqRLAEYSWDEIDVASAEREIAELEAELERldasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQ 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1964 LQKELRALRREHQQELDILKRECEQEAEEKLKQE-QEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE 2042
Cdd:COG4913    725 AEEELDELQDRLEAAEDLARLELRALLEERFAAAlGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAET 804

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198995 2043 AELLES--HQEETQQLHRKIaeKEDDLrrtARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQ 2109
Cdd:COG4913    805 ADLDADleSLPEYLALLDRL--EEDGL---PEYEERFKELLNENSIEFVADLLSKLRRAIREIKERIDP 868
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2186-2229 3.58e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.45  E-value: 3.58e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907198995  2186 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2229
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 408-1002 3.87e-08

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 58.60  E-value: 3.87e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  408 EIAQLRSHIKQMTTQgeelREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVER--ASEEERLRLQHELS 485
Cdd:pfam05557    3 ELIESKARLSQLQNE----KKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKreAEAEEALREQAELN 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  486 RV-RQEAASMAKNSEEQVAALQKLHaEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEEL 564
Cdd:pfam05557   79 RLkKKYLEALNKKLNEKESQLADAR-EVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQN 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  565 ELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHleaEKNKHNKELTALAEQHRTEVEGLQ 644
Cdd:pfam05557  158 LEKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELERLR---EHNKHLNENIENKLLLKEEVEDLK 234

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  645 QQQDSlwterlQSLSQQHQAAVEELREKYQQEkdalLKEKESLFQAHIQDMNE--------KTLEKLDKKQME-LESVSS 715
Cdd:pfam05557  235 RKLER------EEKYREEAATLELEKEKLEQE----LQSWVKLAQDTGLNLRSpedlsrriEQLQQREIVLKEeNSSLTS 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  716 ELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQELtVRRAEKALKDELSrlgalldeRDEH 795
Cdd:pfam05557  305 SARQLEKARRELEQELAQYLKKIEDLNKKLK-RHKALVRRLQRRVLLLTKERDG-YRAILESYDKELT--------MSNY 374

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  796 LRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVldlETEKSLLTKQVVEmethkkH 875
Cdd:pfam05557  375 SPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQE---SLADPSYSKEEVD------S 445

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  876 VCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVekeqarqsLMEKENIILQMREEQAKEIEILKQTLSSKE 955
Cdd:pfam05557  446 LRRKLETLELERQRLREQKNELEMELERRCLQGDYDPKKTKV--------LHLSMNPAAEAYQQRKNQLEKLQAEIERLK 517

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198995  956 ESISILHEEYETKfknQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 1002
Cdd:pfam05557  518 RLLKKLEDDLEQV---LRLPETTSTMNFKEVLDLRKELESAELKNQR 561
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 627-1010 4.25e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 4.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  627 KELTALAEQHRTEVEGLQQQQDSLWTE--RLQSLSQQHQAAVEELrekyQQEKDALLKEKESLFQAHiqdmnEKTLEKLD 704
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSElrRIENRLDELSQELSDA----SRKIGEIEKEIEQLEQEE-----EKLKERLE 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  705 KKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSR 784
Cdd:TIGR02169  741 ELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQK 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  785 LGALLDERDEHLRERQARVQDL-EAHLQKSAGELQQALAKLDLlhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLLT 863
Cdd:TIGR02169  821 LNRLTLEKEYLEKEIQELQEQRiDLKEQIKSIEKEIENLNGKK------------EELEEELEELEAALRDLESRLGDLK 888

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  864 KQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQlqdsqlKNSTVEKEQARQSLMEKENIILQMREEQAKE 943
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE------ELSEIEDPKGEDEEIPEEELSLEDVQAELQR 962

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907198995  944 IEILKQTLsskeESISILHEEyetKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLE 1010
Cdd:TIGR02169  963 VEEEIRAL----EPVNMLAIQ---EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 857-1672 5.23e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 5.23e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  857 TEKSLLTKQVVEMETHKKHVceeldaQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQM 936
Cdd:pfam15921   49 TQIPIFPKYEVELDSPRKII------AYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  937 REEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLkKELENTVLELSQKEK 1016
Cdd:pfam15921  123 QMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVL-QEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1017 QFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGaHQRKLDDVIEAWEKKLSQQAAELRDKHAEQME----EKEQGL 1092
Cdd:pfam15921  202 KKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG-RIFPVEDQLEALKSESQNKIELLLQQHQDRIEqlisEHEVEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1093 GELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVS-LSERESQLQSQVEKLEADLGCSLSEKLS 1171
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSeLREAKRMYEDKIEELEKQLVLANSELTE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1172 LQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckSLHELSKKSLEDKSLNLKSLLEELASQLDSR---CERTKALLE 1248
Cdd:pfam15921  361 ARTERDQFSQESGNLDDQLQKLLADLHKREKEL----SLEKEQNKRLWDRDTGNSITIDHLRRELDDRnmeVQRLEALLK 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1249 AKTNELVCTSRDKADAILARLSQCQRHTATVGE-----ALLRRMgqVSELEAQLTQLTEEQRT---LKSSFQQVTNQLEE 1320
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQlestkEMLRKV--VEELTAKKMTLESSERTvsdLTASLQEKERAIEA 514

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1321 KEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitqLKKELAENINAVTLLREELSEKKSEIASLSKQLSDL-- 1398
Cdd:pfam15921  515 TNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEA----LKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqv 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1399 -GAQLESSISpsdkaeaisalskqheeqelqlqaQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQS 1477
Cdd:pfam15921  591 eKAQLEKEIN------------------------DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR 646

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1478 TIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1557
Cdd:pfam15921  647 AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM 726

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1558 KEVESLNETLKNYNQQRDtehsGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSS---V 1634
Cdd:pfam15921  727 KVAMGMQKQITAKRGQID----ALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQerrL 802

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1907198995 1635 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQ 1672
Cdd:pfam15921  803 KEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQ 840
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 406-754 5.38e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 5.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  406 EDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASE-EERLR-LQHE 483
Cdd:TIGR02169  673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEElEEDLSsLEQE 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  484 LSRVRQEAASMAKNSEEQVAALQKLHaEELASKEQELSRrleARERELQEQMRiALEKSRSEYLKLTQE------KEQQE 557
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEDLHKLE-EALNDLEARLSH---SRIPEIQAELS-KLEEEVSRIEARLREieqklnRLTLE 827

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  558 SLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEqhr 637
Cdd:TIGR02169  828 KEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG-DLKKERDELEAQLRELER--- 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  638 teveglQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVS--- 714
Cdd:TIGR02169  904 ------KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNmla 977

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 1907198995  715 -SELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRR 754
Cdd:TIGR02169  978 iQEYEEVLKRLDELKEKRAKLEEERKAILERIE-EYEKKKR 1017
PTZ00121 PTZ00121
MAEBL; Provisional
 999-1717 5.91e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 5.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  999 KLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELR 1078
Cdd:PTZ00121  1028 KIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTE 1107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1079 DKHAEQMEEKEQGLGELRQKVRIVQSEKEEltkEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSlseRESQLQSQVEKL 1158
Cdd:PTZ00121  1108 TGKAEEARKAEEAKKKAEDARKAEEARKAE---DARKAEEARKAEDAKRVEIARKAEDARKAEEA---RKAEDAKKAEAA 1181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1159 EADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAE-----KELQSCKSLHELSKKSLEDKSLNLKSLLEELA 1233
Cdd:PTZ00121  1182 RKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKkaeavKKAEEAKKDAEEAKKAEEERNNEEIRKFEEAR 1261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1234 SQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTatvgeallRRMGQVSELEAQLTQLTEEQRTLKSSFQQ 1313
Cdd:PTZ00121  1262 MAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA--------DEAKKKAEEAKKADEAKKKAEEAKKKADA 1333

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1314 VTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAvtllrEELSEKKSEIASLSK 1393
Cdd:PTZ00121  1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA-----DEAKKKAEEDKKKAD 1408

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1394 QLSDLGAQLESSISPSDKAEAIsalsKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSrlA 1473
Cdd:PTZ00121  1409 ELKKAAAAKKKADEAKKKAEEK----KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE--A 1482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1474 QHQSTIKDLQAQLDVKATDAREKEEQicllKEDLDRQNKKFECLKGEmEVRKSKMEKKECDLETA---------LKTQTA 1544
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADEAKKAAEA----KKKADEAKKAEEAKKAD-EAKKAEEAKKADEAKKAeekkkadelKKAEEL 1557

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1545 RVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEaelgtVK 1624
Cdd:PTZ00121  1558 KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE-----EK 1632

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1625 KELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREK 1704
Cdd:PTZ00121  1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEA 1712

                          730
                   ....*....|...
gi 1907198995 1705 QVHSLEDKLKNLE 1717
Cdd:PTZ00121  1713 EEKKKAEELKKAE 1725
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
332-939 7.67e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.77  E-value: 7.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  332 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLD---ERLQELEKMKGMvITETKRQmletLELKEDE 408
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEE-IEELEKE----LESLEGS 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  409 IAQLRSHIKQMTTQGEELREQKEKseraaFEELEKALSTAQKTEDAQRRMKMEMDEqmkaveraSEEERLRLQHELSRVR 488
Cdd:PRK03918   254 KRKLEEKIRELEERIEELKKEIEE-----LEEKVKELKELKEKAEEYIKLSEFYEE--------YLDELREIEKRLSRLE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  489 QEAASMAKNSEEqvAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQK 568
Cdd:PRK03918   321 EEINGIEERIKE--LEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  569 KAilTESENKLQELGQEAEAYRTRILELETSLEKsLQESKT------------QSEHLAVHLEAEKNKHNKELTALAEQH 636
Cdd:PRK03918   399 AK--EEIEEEISKITARIGELKKEIKELKKAIEE-LKKAKGkcpvcgrelteeHRKELLEEYTAELKRIEKELKEIEEKE 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  637 RTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFqahiqdmnEKTLEKLDKKQMELESVSSE 716
Cdd:PRK03918   476 RKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEY--------EKLKEKLIKLKGEIKSLKKE 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  717 LSEalrardqlAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSrlgaLLDERDEhL 796
Cdd:PRK03918   548 LEK--------LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLE----LKDAEKE-L 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  797 RERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGayEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHV 876
Cdd:PRK03918   615 EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEELEKRREEI 692

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907198995  877 CEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREE 939
Cdd:PRK03918   693 KKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEE 755
mukB PRK04863
chromosome partition protein MukB;
535-906 1.73e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 56.89  E-value: 1.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  535 MRIALEKSRSEYLKLTQEKEQQeslaleelelQKKAILTESENKLQELGQEAEAyrtrILELETSLEkslQESKTQSEHL 614
Cdd:PRK04863   275 MRHANERRVHLEEALELRRELY----------TSRRQLAAEQYRLVEMARELAE----LNEAESDLE---QDYQAASDHL 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  615 AVHLEAEK--NKHNK------ELTALAEQHRTEVEGLQQQQDSLWTE---------RLQSLSQQHQAAVEELREK---YQ 674
Cdd:PRK04863   338 NLVQTALRqqEKIERyqadleELEERLEEQNEVVEEADEQQEENEARaeaaeeevdELKSQLADYQQALDVQQTRaiqYQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  675 QEKDALLKEKE-----SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVL--------RGDADKM 741
Cdd:PRK04863   418 QAVQALERAKQlcglpDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVrkiagevsRSEAWDV 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  742 KQALEAELEEQRRHHQREVGSISEQQELTVR-----RAEKALKDELSRLGALLDERDE---HLRERQARVQDLE---AHL 810
Cdd:PRK04863   498 ARELLRRLREQRHLAEQLQQLRMRLSELEQRlrqqqRAERLLAEFCKRLGKNLDDEDEleqLQEELEARLESLSesvSEA 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  811 QKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDletekSLLTKQvvEMETHKKHVCEELDAQRAQVQQL 890
Cdd:PRK04863   578 RERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGE-----EFEDSQ--DVTEYMQQLLERERELTVERDEL 650

                          410
                   ....*....|....*.
gi 1907198995  891 ERQRSELEEKVRSLAQ 906
Cdd:PRK04863   651 AARKQALDEEIERLSQ 666
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1572-2156 1.88e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1572 QQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLE-L 1650
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1651 ESAAKVELKRKAEqkIAAIRKQLLSQMEEKTQRYAKDTEnRLSELSAQLKEREKQVHSLEDKLKNLESSphpevpavsRS 1730
Cdd:COG1196    301 EQDIARLEERRRE--LEERLEELEEELAELEEELEELEE-ELEELEEELEEAEEELEEAEAELAEAEEA---------LL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1731 MQSVAASPEQEApdsqdctHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARpsqpEAQHRALSGKLDCTRARQLEDHVL 1810
Cdd:COG1196    369 EAEAELAEAEEE-------LEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEELEELEEALAELEEEE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1811 IGCLPEELEEKmkcslivsqpmGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVE 1890
Cdd:COG1196    438 EEEEEALEEAA-----------EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1891 KLTLKYEKSQSSQQEMDGEnkcVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK-------LSKEVAR 1963
Cdd:COG1196    507 LEGVKAALLLAGLRGLAGA---VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratfLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1964 LQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEA 2043
Cdd:COG1196    584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2044 ELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSVTILELQ 2123
Cdd:COG1196    664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1907198995 2124 TQLAQKTTLISD--SKLKEQELREQVHNLEDRLKR 2156
Cdd:COG1196    744 EEELLEEEALEElpEPPDLEELERELERLEREIEA 778
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 467-1098 2.22e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 56.39  E-value: 2.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  467 KAVERASEEERLRLQHELSRVRQEAASMAKNSEEQVAAL--QKLHAEELASKEQELSRRLEARERelqeqmriALEKSRS 544
Cdd:pfam12128  268 KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELngELSAADAAVAKDRSELEALEDQHG--------AFLDADI 339

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  545 EYLKLTQEKEQQESLALEELELQKKAiLTESENKLQElgqeaeAYRTRILELetslekslqesktqSEHLAVHLEAEKNK 624
Cdd:pfam12128  340 ETAAADQEQLPSWQSELENLEERLKA-LTGKHQDVTA------KYNRRRSKI--------------KEQNNRDIAGIKDK 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  625 HNKELTALAEQHrTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEK----DALLKEKESLFQAHIQDMNEKTL 700
Cdd:pfam12128  399 LAKIREARDRQL-AVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKlrlnQATATPELLLQLENFDERIERAR 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  701 EKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQ------RRHH--QREVGSISEQQELTVR 772
Cdd:pfam12128  478 EEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALD-ELELQlfpqagTLLHflRKEAPDWEQSIGKVIS 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  773 RA------------EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAReqaGA 840
Cdd:pfam12128  557 PEllhrtdldpevwDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQAN---GE 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  841 YEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRA----QVQQLERQRSELEEKVRSLAQLQDSQLKNST 916
Cdd:pfam12128  634 LEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDsaneRLNSLEAQLKQLDKKHQAWLEEQKEQKREAR 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  917 VEKEQARQSLM-EKENIILQMREEQAKEIEILKQTLSS--------------KEESISILH---EEYETKFKNQEKRMEK 978
Cdd:pfam12128  714 TEKQAYWQVVEgALDAQLALLKAAIAARRSGAKAELKAletwykrdlaslgvDPDVIAKLKreiRTLERKIERIAVRRQE 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  979 IKQKAKEMQETkkkLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgISDTVSRLEENQRQQIESLTG--AHQ 1056
Cdd:pfam12128  794 VLRYFDWYQET---WLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAK-LEMERKASEKQQVRLSENLRGlrCEM 869

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|..
gi 1907198995 1057 RKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQK 1098
Cdd:pfam12128  870 SKLATLKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKK 911
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 474-1403 2.65e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 56.34  E-value: 2.65e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  474 EEERLRLQHELSRVRQEAASMAKN-----------SEEQVAALQKLHAE-ELASKEQELSRRLEARERELQE-----QMR 536
Cdd:pfam01576    4 EEEMQAKEEELQKVKERQQKAESElkelekkhqqlCEEKNALQEQLQAEtELCAEAEEMRARLAARKQELEEilhelESR 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  537 IALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESK-------- 608
Cdd:pfam01576   84 LEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKlleerise 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  609 -----TQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDslWTERLQSLSQQHQAAVEELREKYQQEKDALLKE 683
Cdd:pfam01576  164 ftsnlAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEK--AKRKLEGESTDLQEQIAELQAQIAELRAQLAKK 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  684 KESLfQAHIQDMNEKTLEK--LDKKQMELESVSSELSEALrardqlaEELSVLRGDADKMKQALEAELEEQRRHHQREVG 761
Cdd:pfam01576  242 EEEL-QAALARLEEETAQKnnALKKIRELEAQISELQEDL-------ESERAARNKAEKQRRDLGEELEALKTELEDTLD 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  762 SISEQQELTVRRAEKalkdelsrLGALLDERDEHLRERQARVQDLEahlqksagelQQALAKLDLLHSEQSAAREQAGAY 841
Cdd:pfam01576  314 TTAAQQELRSKREQE--------VTELKKALEEETRSHEAQLQEMR----------QKHTQALEELTEQLEQAKRNKANL 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  842 EEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL--------AQLQDSQLK 913
Cdd:pfam01576  376 EKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLqselesvsSLLNEAEGK 455

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  914 NSTVEKE--------QARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKE 985
Cdd:pfam01576  456 NIKLSKDvsslesqlQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEE 535

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  986 MQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAqiLEMAQANSAGISDTVSRLEENQRQQIESLTgAHQRKLDDVIeA 1065
Cdd:pfam01576  536 DAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDK--LEKTKNRLQQELDDLLVDLDHQRQLVSNLE-KKQKKFDQML-A 611

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1066 WEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEV----ARLKEAVSGQDVALAGLQGQLEQKSAvi 1141
Cdd:pfam01576  612 EEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNkqlrAEMEDLVSSKDDVGKNVHELERSKRA-- 689

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1142 vsLSERESQLQSQVEKLEADLGCSLSEKLSLqeelaELKLLADKSQLrvseltgqvqaaEKELQSCKSLHELSKKSLedk 1221
Cdd:pfam01576  690 --LEQQVEEMKTQLEELEDELQATEDAKLRL-----EVNMQALKAQF------------ERDLQARDEQGEEKRRQL--- 747

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1222 slnLKSLLEELASQLDSRCERTKALLEAKTNELvctsrdkadailaRLSQCQRHTATVGEALLRRMGQVSELEAQLTQLT 1301
Cdd:pfam01576  748 ---VKQVRELEAELEDERKQRAQAVAAKKKLEL-------------DLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQ 811

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1302 EEQRTLKSSFQQVTNQLEEKEKQIKTMKADiegLLTEKEALQQEGGQQRQAASEKEscitQLKKELAENINAVTLLREEL 1381
Cdd:pfam01576  812 RELEEARASRDEILAQSKESEKKLKNLEAE---LLQLQEDLAASERARRQAQQERD----ELADEIASGASGKSALQDEK 884

                          970       980
                   ....*....|....*....|..
gi 1907198995 1382 SEKKSEIASLSKQLSDLGAQLE 1403
Cdd:pfam01576  885 RRLEARIAQLEEELEEEQSNTE 906
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 620-958 2.77e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.11  E-value: 2.77e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  620 AEKNKHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQA----HIQDM 695
Cdd:COG3096    278 NERRELSERALELRRELFGARRQLAEEQYRL--VEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQekieRYQED 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  696 NEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaelEEQRR--HHQREVGSISEQQELTVRR 773
Cdd:COG3096    356 LEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALD---VQQTRaiQYQQAVQALEKARALCGLP 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  774 --AEKALKDELSRLGALLDERDEHLRERQARVQDLEAH----------LQKSAGE------------------------- 816
Cdd:COG3096    433 dlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAArrqfekayelVCKIAGEversqawqtarellrryrsqqalaq 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  817 ----LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLER 892
Cdd:COG3096    513 rlqqLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRA 592

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198995  893 QRSELEEKVRSLAQLQDS--QLKNSTVEKEQARQSLMEKeniiLQMREEQAKEIEILKQTLSSKEESI 958
Cdd:COG3096    593 RIKELAARAPAWLAAQDAleRLREQSGEALADSQEVTAA----MQQLLEREREATVERDELAARKQAL 656
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 800-1021 2.91e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.16  E-value: 2.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  800 QARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEE 879
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  880 LDAQRAQVQQLER--QRSELEEKVRSLAQLQDSQ--LKNSTVEKE--QARQSLMEKENIILQMREEQAKEIEILKQTLSS 953
Cdd:COG4942     99 LEAQKEELAELLRalYRLGRQPPLALLLSPEDFLdaVRRLQYLKYlaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198995  954 KEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQ 1021
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 332-697 3.14e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.83  E-value: 3.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  332 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDEIAQ 411
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE------------EELAEAEAEIEE 786

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  412 LRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEmdeqmkaverasEEERLRLQHELSRVRQEA 491
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT------------ERRLEDLEEQIEELSEDI 854

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  492 ASMAKNSEEQVAALQKLHAE-ELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEqqeslaleelelQKKA 570
Cdd:TIGR02168  855 ESLAAEIEELEELIEELESElEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE------------ELRE 922

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  571 ILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQdsl 650
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELK--- 999

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198995  651 wtERLQSLSQQHqAAVEELREKYQQEKDALLKEKESLFQAHIQDMNE 697
Cdd:TIGR02168 1000 --ERYDFLTAQK-EDLTEAKETLEEAIEEIDREARERFKDTFDQVNE 1043
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
332-899 3.26e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.82  E-value: 3.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  332 KTLEMLQQRVKRQENLLQRC---KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDE 408
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYeeqREQARETRDEADEVLEEHEERREELETLEAEIEDLR------------ETIAETERE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  409 IAQLRSHIKQMTTQGEELREqkEKSERAAFEELEKAlstAQKTEDAQRRmkmEMDEQMKAVERASEEERLRLQhelsRVR 488
Cdd:PRK02224   274 REELAEEVRDLRERLEELEE--ERDDLLAEAGLDDA---DAEAVEARRE---ELEDRDEELRDRLEECRVAAQ----AHN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  489 QEAASMAKNseeqvaalqklhAEELASKEQELSRRLEARERELQEQmRIALEKSRSEYLKLTQEKEQQESLALEELELqk 568
Cdd:PRK02224   342 EEAESLRED------------ADDLEERAEELREEAAELESELEEA-REAVEDRREEIEELEEEIEELRERFGDAPVD-- 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  569 kaiLTESENKLQELGQEAEAYRTRILELETSLeKSLQESKTQSEHL---------------AVHLEA--EKNKHNKELTA 631
Cdd:PRK02224   407 ---LGNAEDFLEELREERDELREREAELEATL-RTARERVEEAEALleagkcpecgqpvegSPHVETieEDRERVEELEA 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  632 LAEQHRTEVEGLQQQqdslwTERLQSLSQQhQAAVEELREKYQQEKDALLKEKESLfqahiqDMNEKTLEKLDKKQMELE 711
Cdd:PRK02224   483 ELEDLEEEVEEVEER-----LERAEDLVEA-EDRIERLEERREDLEELIAERRETI------EEKRERAEELRERAAELE 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  712 SVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRhhqrevgsISEQQEL--TVRRAEKALKDELSRLGALL 789
Cdd:PRK02224   551 AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER--------IRTLLAAiaDAEDEIERLREKREALAELN 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  790 DERDEHLRERQARVQDLEAHLQKSAGElqqalakldllhseqsAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQV--V 867
Cdd:PRK02224   623 DERRERLAEKRERKRELEAEFDEARIE----------------EAREDKERAEEYLEQVEEKLDELREERDDLQAEIgaV 686

                          570       580       590
                   ....*....|....*....|....*....|...
gi 1907198995  868 EMETHK-KHVCEELDAQRAQVQQLERQRSELEE 899
Cdd:PRK02224   687 ENELEElEELRERREALENRVEALEALYDEAEE 719
PTZ00121 PTZ00121
MAEBL; Provisional
 705-1513 3.88e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 3.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  705 KKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQRevgsiseqqeltVRRAEKALKDELSR 784
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAED------------ARKAEEARKAEDAK 1152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  785 LGALLDERDEHLRERQARVQDlEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQlaQMQQKVLDLETEKSLltK 864
Cdd:PTZ00121  1153 RVEIARKAEDARKAEEARKAE-DAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEE--RKAEEARKAEDAKKA--E 1227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  865 QVVEMETHKKhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEI 944
Cdd:PTZ00121  1228 AVKKAEEAKK---DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA 1304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  945 EILKQTLSSKEESisilhEEYETKFKNQEKRMEKIKQKAKEmqetkKKLLDQEAKLKKELENTVLELSQKEKQfnaqile 1024
Cdd:PTZ00121  1305 DEAKKKAEEAKKA-----DEAKKKAEEAKKKADAAKKKAEE-----AKKAAEAAKAEAEAAADEAEAAEEKAE------- 1367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1025 maqansagiSDTVSRLEENQRQQiesltgAHQRKLDDVIEAWEKKlsqQAAELRDKHAEQMEEKEQGlgelrqkvrivQS 1104
Cdd:PTZ00121  1368 ---------AAEKKKEEAKKKAD------AAKKKAEEKKKADEAK---KKAEEDKKKADELKKAAAA-----------KK 1418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1105 EKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAvivslsERESQLQSQVEKLEAdlgcslSEKLSLQEELAELKLLAD 1184
Cdd:PTZ00121  1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA------EEAKKAEEAKKKAEE------AKKADEAKKKAEEAKKAD 1486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1185 KSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADA 1264
Cdd:PTZ00121  1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKA 1566

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1265 ILARLSQCQRHTATVGEALLRRMGQVSELEaqLTQLTEEQRTLKSsfQQVTNQLEEKEKQIKTMKAdieglltekEALQQ 1344
Cdd:PTZ00121  1567 EEAKKAEEDKNMALRKAEEAKKAEEARIEE--VMKLYEEEKKMKA--EEAKKAEEAKIKAEELKKA---------EEEKK 1633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1345 EGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQhee 1424
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKK--- 1710

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1425 qelqlqaqLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLK 1504
Cdd:PTZ00121  1711 --------EAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782


                   ....*....
gi 1907198995 1505 EDLDRQNKK 1513
Cdd:PTZ00121  1783 EELDEEDEK 1791
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
806-1034 4.48e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 55.41  E-value: 4.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  806 LEAHLQKSAGELQQALAKLDllhSEQSAAREQAGAYEEQLAQMQQK--VLDLETEKSLLTKQVVEMETHKKHVCEELDAQ 883
Cdd:COG3206    162 LEQNLELRREEARKALEFLE---EQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELAEA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  884 RAQVQQLERQRSELEEKVRSLAQLQ-----DSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESI 958
Cdd:COG3206    239 EARLAALRAQLGSGPDALPELLQSPviqqlRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  959 SILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL--LDQEAKLKKELENTVL------ELSQKEKQFNAQILEMAQANS 1030
Cdd:COG3206    319 EAELEALQAREASLQAQLAQLEARLAELPELEAELrrLEREVEVARELYESLLqrleeaRLAEALTVGNVRVIDPAVVPL 398


                   ....
gi 1907198995 1031 AGIS 1034
Cdd:COG3206    399 KPVS 402
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 765-1329 4.50e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.41  E-value: 4.50e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  765 EQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSeqsaareqagayeeQ 844
Cdd:TIGR04523  130 EKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKN--------------K 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  845 LAQMQQKVLDLETEKS---LLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQD---SQLKNSTVE 918
Cdd:TIGR04523  196 LLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNkikKQLSEKQKE 275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  919 KEQARQSLMEKENIILQMReeqaKEIEILKQtlsskeESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA 998
Cdd:TIGR04523  276 LEQNNKKIKELEKQLNQLK----SEISDLNN------QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQIS 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  999 KLKKELENTVLELSQKEKQfnaqilemaqansagisdtvsrLEENQrQQIESLTGAHQRKLDDVieaweKKLSQQAAELR 1078
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRE----------------------LEEKQ-NEIEKLKKENQSYKQEI-----KNLESQINDLE 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1079 DKHAEQMEEKEQglgeLRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKL 1158
Cdd:TIGR04523  398 SKIQNQEKLNQQ----KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVL 473

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1159 EADLGCSLSEKLSLQEELAE-----LKLLADKSQL--RVSELTGQVQAA---EKELQSCKSLHELSKKSLEDKSLNLKSL 1228
Cdd:TIGR04523  474 SRSINKIKQNLEQKQKELKSkekelKKLNEEKKELeeKVKDLTKKISSLkekIEKLESEKKEKESKISDLEDELNKDDFE 553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1229 L--EELASQLDSRCERTKALLEAKTNELVctSRDKADAILARLSQCQRhtaTVGEALLRRMGQVSELEAQLTQLTEEQRT 1306
Cdd:TIGR04523  554 LkkENLEKEIDEKNKEIEELKQTQKSLKK--KQEEKQELIDQKEKEKK---DLIKEIEEKEKKISSLEKELEKAKKENEK 628

                          570       580
                   ....*....|....*....|...
gi 1907198995 1307 LKSSFQQVTNQLEEKEKQIKTMK 1329
Cdd:TIGR04523  629 LSSIIKNIKSKKNKLKQEVKQIK 651
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 568-1684 5.70e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.44  E-value: 5.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  568 KKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQES---KTQSEHL---------------AVHLE--------AE 621
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSihlEKEIKDLfdkyleiddeiiyinKLKLElkekikniSD 614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  622 KNKHNK---ELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQ--------- 689
Cdd:TIGR01612  615 KNEYIKkaiDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNELSSIVKenaidnted 694

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  690 -AHIQDMNEKTLEKLDKKQ-MELESVSSELSEALRARDQLAEELSvlrgdadKMKQALEAELeeqrrhhQREVGSISEQq 767
Cdd:TIGR01612  695 kAKLDDLKSKIDKEYDKIQnMETATVELHLSNIENKKNELLDIIV-------EIKKHIHGEI-------NKDLNKILED- 759

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  768 eltVRRAEKALKdelSRLGALLDERDEhLRERQARVQDLEAHL--QKSAGELQQALAKLDLLHSEQSAarEQAGAYEEQL 845
Cdd:TIGR01612  760 ---FKNKEKELS---NKINDYAKEKDE-LNKYKSKISEIKNHYndQINIDNIKDEDAKQNYDKSKEYI--KTISIKEDEI 830

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  846 AQMQQKVLDLETEKSLLTKQVVEMETHKKhvcEELDAQRAQVQQL---------ERQRSELEEKVRSLAQLQDSqlKNST 916
Cdd:TIGR01612  831 FKIINEMKFMKDDFLNKVDKFINFENNCK---EKIDSEHEQFAELtnkikaeisDDKLNDYEKKFNDSKSLINE--INKS 905

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  917 VEKEQARQSLMEKEN-----------IILQMREEQAKEIEILKQTLSSKEESISIlHEEYETKFKN----QEKRMEKIKQ 981
Cdd:TIGR01612  906 IEEEYQNINTLKKVDeyikicentkeSIEKFHNKQNILKEILNKNIDTIKESNLI-EKSYKDKFDNtlidKINELDKAFK 984

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  982 KAK------EMQETKKKLLDQEAKLKKELENTVL-ELSQKEKQFNAQILEMAQANS----------AGISDTVSRLEENQ 1044
Cdd:TIGR01612  985 DASlndyeaKNNELIKYFNDLKANLGKNKENMLYhQFDEKEKATNDIEQKIEDANKnipnieiaihTSIYNIIDEIEKEI 1064

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1045 RQQIESLTGAHQRKLDDVIEAWEK--------KLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKE---- 1112
Cdd:TIGR01612 1065 GKNIELLNKEILEEAEINITNFNEikeklkhyNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKseny 1144

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1113 VARLKEAVSG-QDVALAGLQGQ----LEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQE----------ELA 1177
Cdd:TIGR01612 1145 IDEIKAQINDlEDVADKAISNDdpeeIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEvkginlsygkNLG 1224

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1178 ELKLLADKSQLRVSELTgqVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCT 1257
Cdd:TIGR01612 1225 KLFLEKIDEEKKKSEHM--IKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISD 1302

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1258 SRDKADAIL-----------------ARLSQCQRHTATVGEAL-----LRRMGQVSELEAQLTQLTEEQRTLKSSFQQVT 1315
Cdd:TIGR01612 1303 IREKSLKIIedfseesdindikkelqKNLLDAQKHNSDINLYLneianIYNILKLNKIKKIIDEVKEYTKEIEENNKNIK 1382

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1316 NQLEEKEKQIKTMKAD---------IEGLLTEK---EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLRE-ELS 1382
Cdd:TIGR01612 1383 DELDKSEKLIKKIKDDinleeckskIESTLDDKdidECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNiEMA 1462

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1383 EKKSE-IASLSKQ--LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKeKMSALEqvdhWSN 1459
Cdd:TIGR01612 1463 DNKSQhILKIKKDnaTNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLN-KYSALA----IKN 1537

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1460 KFSEWKKKAQSRLAQhqstIKDLQAQLDVKATDAREKEEQIcllkedldrqnkKFECLKGEMEVRKS-KMEKKECDLETA 1538
Cdd:TIGR01612 1538 KFAKTKKDSEIIIKE----IKDAHKKFILEAEKSEQKIKEI------------KKEKFRIEDDAAKNdKSNKAAIDIQLS 1601

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1539 LKTQTARVVELEDCVTQRK---KEVESLNETLKNYN-QQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETvlrlrehvs 1614
Cdd:TIGR01612 1602 LENFENKFLKISDIKKKINdclKETESIEKKISSFSiDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDK--------- 1672

                         1210      1220      1230      1240      1250      1260      1270
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198995 1615 sleaelgtvKKELEHVNSSVKSRDGELKALEDKLELESAAKV-ELKRKAEQKIAAIRKQLLSQMEEKTQRY 1684
Cdd:TIGR01612 1673 ---------KKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIkEIAIANKEEIESIKELIEPTIENLISSF 1734
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
338-889 6.35e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 6.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  338 QQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQmLETLELKEDEIAQLRSHIK 417
Cdd:COG4913    287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLERE-IERLERELEERERRRARLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  418 QMTTQGEElreqKEKSERAAFEEL-EKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERlRLQHELSRVRQeaasMAK 496
Cdd:COG4913    366 ALLAALGL----PLPASAEEFAALrAEAAALLEALEEELEALEEALAEAEAALRDLRRELR-ELEAEIASLER----RKS 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  497 NSEEQVAALQKLHAEELASKEQELS--------RRLEAR-----EREL----------QEQMRIALEKSRSEYLK--LTQ 551
Cdd:COG4913    437 NIPARLLALRDALAEALGLDEAELPfvgelievRPEEERwrgaiERVLggfaltllvpPEHYAAALRWVNRLHLRgrLVY 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  552 EKEQQESLALEELELQKKAILteseNKLQELGQEAEAYRTRILELETSLEK--SLQESKT---------QSEHLAVHLEA 620
Cdd:COG4913    517 ERVRTGLPDPERPRLDPDSLA----GKLDFKPHPFRAWLEAELGRRFDYVCvdSPEELRRhpraitragQVKGNGTRHEK 592

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  621 EKNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQhQAAVEELREKYQQEKDALLKEKESLF--------QAHI 692
Cdd:COG4913    593 DDRRRIRSRYVLGFDNRAKLAALEAELAEL-EEELAEAEER-LEALEAELDALQERREALQRLAEYSWdeidvasaEREI 670

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  693 QDmNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVR 772
Cdd:COG4913    671 AE-LEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  773 RAEKALKDelsrlgALLDERDEHLRER-QARVQDLEAHLQKSAGELQQALAKL----DLLHSEQSAAREQAGAYEEQLAQ 847
Cdd:COG4913    750 LLEERFAA------ALGDAVERELRENlEERIDALRARLNRAEEELERAMRAFnrewPAETADLDADLESLPEYLALLDR 823

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1907198995  848 MQQKVL-DLETE-KSLLTKQvveMETHKKHVCEELDAQRAQVQQ 889
Cdd:COG4913    824 LEEDGLpEYEERfKELLNEN---SIEFVADLLSKLRRAIREIKE 864
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
498-1108 9.24e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.30  E-value: 9.24e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  498 SEEQVAALQKLHAEELASKEQELSRrLEARERELQEQmriaLEKSRSEYLKLTQEKEQQESLALEELELQKKaiLTESEN 577
Cdd:PRK03918   187 RTENIEELIKEKEKELEEVLREINE-ISSELPELREE----LEKLEKEVKELEELKEEIEELEKELESLEGS--KRKLEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  578 KLQELGQEAEAYRTRILELETSLE--KSLQESKTQSEHLaVHLEAEKNKHNKELTALAEQHRTEVEGLQqqqdslwtERL 655
Cdd:PRK03918   260 KIRELEERIEELKKEIEELEEKVKelKELKEKAEEYIKL-SEFYEEYLDELREIEKRLSRLEEEINGIE--------ERI 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  656 QSLSQQhQAAVEELREKYQ--QEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSV 733
Cdd:PRK03918   331 KELEEK-EERLEELKKKLKelEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISK 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  734 LRGDADKMKQaleaeleeqrrhhqrevgsISEQQELTVRRAEKAlKDELSRLGALLDE--RDEHLRERQARVQDLEAHLQ 811
Cdd:PRK03918   410 ITARIGELKK-------------------EIKELKKAIEELKKA-KGKCPVCGRELTEehRKELLEEYTAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  812 KSAGELQQALAKLDLLHSEQSAAREQAGAYE--EQLAQMQQKVLDLETEKslLTKQVVEMETHKkhvcEELDAQRAQVQQ 889
Cdd:PRK03918   470 EIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYNLEE--LEKKAEEYEKLK----EKLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  890 LERQRSELEEKVRSLAQLQDsqlKNSTVEKeqarqslmEKENIILQMREEQAKEIEILKQTLSSKEEsisiLHEEYeTKF 969
Cdd:PRK03918   544 LKKELEKLEELKKKLAELEK---KLDELEE--------ELAELLKELEELGFESVEELEERLKELEP----FYNEY-LEL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  970 KNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEEnqrqQIE 1049
Cdd:PRK03918   608 KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRA----ELE 683

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198995 1050 SLtgahqRKLDDVIEAWEKKLSQQAAELRD--KHAEQMEEKEQGLGELRQKVRIVQSEKEE 1108
Cdd:PRK03918   684 EL-----EKRREEIKKTLEKLKEELEEREKakKELEKLEKALERVEELREKVKKYKALLKE 739
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
407-1024 9.31e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.28  E-value: 9.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  407 DEIAQLRSHIKQMTTQGEELREQKEKSeRAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVErASEEERLRLQHELSR 486
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQREQA-RETRDEADEVLEEHEERREELETLEAEIEDLRETIA-ETEREREELAEEVRD 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  487 VRQEAASMAKNSEEQVA--ALQKLHAEELASKEQELSRRLEARERELQEQmRIALEKSRSEYLKLTQEKEqqeslaleel 564
Cdd:PRK02224   284 LRERLEELEEERDDLLAeaGLDDADAEAVEARREELEDRDEELRDRLEEC-RVAAQAHNEEAESLREDAD---------- 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  565 elqkkailtesenklqELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaeknkhnkELTALAEQHRTEVEGLQ 644
Cdd:PRK02224   353 ----------------DLEERAEELREEAAELESELEEAREAVEDRREEIE------------ELEEEIEELRERFGDAP 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  645 QQQDSLwTERLQSLSQQHQAAVE---ELREKYQQEKDALlKEKESLFQAHIQDMNEKTLEkldkkqmelesvSSELSEAL 721
Cdd:PRK02224   405 VDLGNA-EDFLEELREERDELREreaELEATLRTARERV-EEAEALLEAGKCPECGQPVE------------GSPHVETI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  722 RARDQLAEELSVLRGDADKMKQALEAELEEqrrhhqrevgsiSEQQELTVRRAEKaLKDELSRLGALLDERDEHLRERQA 801
Cdd:PRK02224   471 EEDRERVEELEAELEDLEEEVEEVEERLER------------AEDLVEAEDRIER-LEERREDLEELIAERRETIEEKRE 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  802 RVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLtkqvvEMETHKKHVCEELD 881
Cdd:PRK02224   538 RAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLL-----AAIADAEDEIERLR 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  882 AQRAQVQQLERQR----SELEEKVRSL-AQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKeieiLKQTLSSKEE 956
Cdd:PRK02224   613 EKREALAELNDERrerlAEKRERKRELeAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDD----LQAEIGAVEN 688

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  957 SIsilheeyetkfknqeKRMEKIKQKAKEMQETKKKL--LDQEAklkKELENTVLELSQKEKQFNAQILE 1024
Cdd:PRK02224   689 EL---------------EELEELRERREALENRVEALeaLYDEA---EELESMYGDLRAELRQRNVETLE 740
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
395-929 1.02e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.15  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  395 KRQMLETLELKEDeIAQLRSHIKQ---MTTQGEELREQKEKSE--RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAv 469
Cdd:COG4913    214 REYMLEEPDTFEA-ADALVEHFDDlerAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLE- 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  470 erASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAEELAS---KEQELSRRLEARERELQEQMRIALE-KSRSE 545
Cdd:COG4913    292 --LLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNggdRLEQLEREIERLERELEERERRRARlEALLA 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  546 YLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKnkh 625
Cdd:COG4913    370 ALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALR--- 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  626 nKELTALAEQHRTEV----EGLQ-QQQDSLWT---ERL---QSLS----QQHQAAVeelREKYQQEKDAL----LKEKES 686
Cdd:COG4913    447 -DALAEALGLDEAELpfvgELIEvRPEEERWRgaiERVlggFALTllvpPEHYAAA---LRWVNRLHLRGrlvyERVRTG 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  687 LFQAHIQDMNEKTL-EKLDKK--------QMELESVSS--------ELSEALRA------------------RDQLAEEL 731
Cdd:COG4913    523 LPDPERPRLDPDSLaGKLDFKphpfrawlEAELGRRFDyvcvdspeELRRHPRAitragqvkgngtrhekddRRRIRSRY 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  732 sVLRGDADKMKQALEAELEEQRRHHQRevgsiSEQQELTVRRAEKALKDELSRLGALLDerdehLRERQARVQDLEAHLQ 811
Cdd:COG4913    603 -VLGFDNRAKLAALEAELAELEEELAE-----AEERLEALEAELDALQERREALQRLAE-----YSWDEIDVASAEREIA 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  812 ksagELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDA-----QRAQ 886
Cdd:COG4913    672 ----ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaedlaRLEL 747

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1907198995  887 VQQLERQRSEL--EEKVRSLAQLQDSQLKNSTVEKEQARQSLMEK 929
Cdd:COG4913    748 RALLEERFAAAlgDAVERELRENLEERIDALRARLNRAEEELERA 792
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1189-1717 1.66e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1189 RVSELTGQVQAAEK--ELQSCKSLHELSKKSLEDKSLNLK-SLLEELASQLDSRCERTKALLEAKTNEL------VCTSR 1259
Cdd:COG1196    201 QLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELeelrleLEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1260 DKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKssfqqvtNQLEEKEKQIKTMKADIEGLLTEK 1339
Cdd:COG1196    281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1340 EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISpsdKAEAISALS 1419
Cdd:COG1196    354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1420 KQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQStiKDLQAQLDVKATDAREKEEQ 1499
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1500 ICLLKEDLDRQNKKFECLKGEMEVRKSkmekkecdLETALktQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT--- 1576
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAA--------YEAAL--EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflp 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1577 ----EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGEL-KALEDKLELE 1651
Cdd:COG1196    579 ldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLReVTLEGEGGSA 658

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198995 1652 SAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 686-910 1.82e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 1.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  686 SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALeAELEEQRRHHQREVGSISE 765
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI-RALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  766 QQElTVRRAEKALKDELSRLGALLderdehlrERQARVQDLEAHLqkSAGELQQALAKLDLLHSEQSAAREQAGAYEEQL 845
Cdd:COG4942     91 EIA-ELRAELEAQKEELAELLRAL--------YRLGRQPPLALLL--SPEDFLDAVRRLQYLKYLAPARREQAEELRADL 159

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198995  846 AQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDS 910
Cdd:COG4942    160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 576-925 2.15e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.42  E-value: 2.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  576 ENKLQELGQEAEAYRTRILELETSLEK--SLQESKTQ--SEHLAVHLEAEKnkhnKELTALAEQHRTEVEGLQQQQdslw 651
Cdd:COG3096    784 EKRLEELRAERDELAEQYAKASFDVQKlqRLHQAFSQfvGGHLAVAFAPDP----EAELAALRQRRSELERELAQH---- 855

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  652 terlQSLSQQHQAAVEELREKyQQEKDALLKEKESLFQAHIQDMnektLEKLDKKQMELESVSSELSEALRARDQLAEEL 731
Cdd:COG3096    856 ----RAQEQQLRQQLDQLKEQ-LQLLNKLLPQANLLADETLADR----LEELREELDAAQEAQAFIQQHGKALAQLEPLV 926

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  732 SVLRGDA---DKMKQALEAELEEQRRHHQRevgsISEQQELTVRRAEKALKDELSRLGALlDERDEHLRER-----QARV 803
Cdd:COG3096    927 AVLQSDPeqfEQLQADYLQAKEQQRRLKQQ----IFALSEVVQRRPHFSYEDAVGLLGEN-SDLNEKLRARleqaeEARR 1001

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  804 QDLEAhLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSlltkqvvemETHKKHVCEELDAQ 883
Cdd:COG3096   1002 EAREQ-LRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEERA---------RIRRDELHEELSQN 1071

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1907198995  884 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 925
Cdd:COG3096   1072 RSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQA 1113
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 777-1003 2.47e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  777 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLE 856
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  857 TE----KSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENI 932
Cdd:COG4942     97 AEleaqKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198995  933 ILQMREEQAKEIEILKQTLSSKEESISILheeyETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKE 1003
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARL----EKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1917-2160 2.82e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 2.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1917 EDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK------LSKEVARLQKELRALR-REHQQELDILKREcEQE 1989
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKaerykeLKAELRELELALLVLRlEELREELEELQEE-LKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1990 AEEKLKQEQEDLELKHTStLKQLMREFNtQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRR 2069
Cdd:TIGR02168  251 AEEELEELTAELQELEEK-LEELRLEVS-ELEEEIEELQKELYALANEISRLEQQ-KQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2070 TARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSVTilELQTQLAQKTTLISDSKLKEQELREQVHN 2149
Cdd:TIGR02168  328 LESKLDE-LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE--ELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250
                   ....*....|.
gi 1907198995 2150 LEDRLKRYEKN 2160
Cdd:TIGR02168  405 LEARLERLEDR 415
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 360-1006 2.89e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.66  E-value: 2.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  360 EQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAafE 439
Cdd:TIGR00618  179 TQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQ--L 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  440 ELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHE-LSRVRQEAASMAKNSEEQVAALQKLHAEELASKEQ 518
Cdd:TIGR00618  257 KKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKaVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQ 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  519 ELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKkaILTESENKLQELGQEAEAYRTrilELET 598
Cdd:TIGR00618  337 QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQ--QKTTLTQKLQSLCKELDILQR---EQAT 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  599 SLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQqqdslwterlqSLSQQHQAAVEELREKYQQEKD 678
Cdd:TIGR00618  412 IDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEK-----------IHLQESAQSLKEREQQLQTKEQ 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  679 ALLKEKEslfqahIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQ------ALEAELEEQ 752
Cdd:TIGR00618  481 IHLQETR------KKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQletseeDVYHQLTSE 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  753 RRHHQREvgsisEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLdllhsEQS 832
Cdd:TIGR00618  555 RKQRASL-----KEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKL-----QPE 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  833 AAREQAGAYEEQLAQMQQKvldletekSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQlQDSQL 912
Cdd:TIGR00618  625 QDLQDVRLHLQQCSQELAL--------KLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKE-QLTYW 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  913 KNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKK 992
Cdd:TIGR00618  696 KEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQ 775

                          650
                   ....*....|....
gi 1907198995  993 LLDQEAKLKKELEN 1006
Cdd:TIGR00618  776 TGAELSHLAAEIQF 789
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1301-1513 2.95e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1301 TEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREE 1380
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1381 LSEKKSEIASLSKQLSDLGAQ--LESSISPSDKAEAISALS---------KQHEEQELQLQAQLQELSLKVDALSKEKMS 1449
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQppLALLLSPEDFLDAVRRLQylkylaparREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198995 1450 ALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKK 1513
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 352-685 3.05e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.43  E-value: 3.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  352 KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQmletlelkedeiAQLRSHIKQMTTQGEELREQKE 431
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQ------------AEMDRQAAIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  432 KSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKaVERASEEERLRLQHELSR-VRQEAASMAKNSEEQVAALQKLHA 510
Cdd:pfam17380  349 ELERIRQEERKRELERIRQEEIAMEISRMRELERLQ-MERQQKNERVRQELEAARkVKILEEERQRKIQQQKVEMEQIRA 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  511 EELASKEQELSRRLEARERELqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKlQELGQEAEAYR 590
Cdd:pfam17380  428 EQEEARQREVRRLEEERAREM-ERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRR-KILEKELEERK 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  591 TRILELETslEKSLQESKTQSEHLAVHLEAEKNKHNKELTalAEQHRTEVEGLQQQQDSLWTERlqslsqQHQAAVEELR 670
Cdd:pfam17380  506 QAMIEEER--KRKLLEKEMEERQKAIYEEERRREAEEERR--KQQEMEERRRIQEQMRKATEER------SRLEAMERER 575

                          330
                   ....*....|....*
gi 1907198995  671 EKYQQEKDALLKEKE 685
Cdd:pfam17380  576 EMMRQIVESEKARAE 590
PRK11281 PRK11281
mechanosensitive channel MscK;
763-1113 3.58e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.61  E-value: 3.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  763 ISEQQELTVrrAEKALKDELSRLGALLDERDEHlrerQARVQDLEAHLQKSAGELQQALAKLDLL-HSEQSAAREQAGAY 841
Cdd:PRK11281    48 LNKQKLLEA--EDKLVQQDLEQTLALLDKIDRQ----KEETEQLKQQLAQAPAKLRQAQAELEALkDDNDEETRETLSTL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  842 -----EEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSEL---------EEKVRSLAQL 907
Cdd:PRK11281   122 slrqlESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGkvggkalrpSQRVLLQAEQ 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  908 QDSQLKNstvekEQARQSLmeKENIILQM-----REEQAKEIEILKQTLSSKEESISilheeyetkfknqEKRMEKIKQK 982
Cdd:PRK11281   202 ALLNAQN-----DLQRKSL--EGNTQLQDllqkqRDYLTARIQRLEHQLQLLQEAIN-------------SKRLTLSEKT 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  983 AKEMQETKKK-------LLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQansagISDTVSRLEENQRQQIESLTGA- 1054
Cdd:PRK11281   262 VQEAQSQDEAariqanpLVAQELEINLQLSQRLLKATEKLNTLTQQNLRVKN-----WLDRLTQSERNIKEQISVLKGSl 336

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1055 --------HQRKL--DDVIeaweKKLSQQAAELRDKHAEQMEEKEQgLGELRQKV-RIVQSEKEELTKEV 1113
Cdd:PRK11281   337 llsrilyqQQQALpsADLI----EGLADRIADLRLEQFEINQQRDA-LFQPDAYIdKLEAGHKSEVTDEV 401
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1037-1717 3.81e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 3.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1037 VSRLEENQRQQIESLtgahQRKLDDVIEAWEKK---LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEV 1113
Cdd:pfam15921   76 IERVLEEYSHQVKDL----QRRLNESNELHEKQkfyLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1114 ARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLR---- 1189
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILReldt 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1190 -VSELTGQVQAAEKELQSCKSlhelskksledkslNLKSLLEELASQLDSRCERTKALLEAKTN---ELVCTSRDKADAI 1265
Cdd:pfam15921  232 eISYLKGRIFPVEDQLEALKS--------------ESQNKIELLLQQHQDRIEQLISEHEVEITgltEKASSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1266 LARLSQCQRHTATVGEALLRrmgQVSELEAQLTQLTEEQRTLKSSFQqvtNQLEEKEKQIKTMKADIEGLLTEKEALQQE 1345
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSELREAKRMYE---DKIEELEKQLVLANSELTEARTERDQFSQE 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1346 GG------QQRQAASEKESCITQLKKELAENI------NAVTL--LREELSEKKSEIASLSKQL----SDLGAQLESSIS 1407
Cdd:pfam15921  372 SGnlddqlQKLLADLHKREKELSLEKEQNKRLwdrdtgNSITIdhLRRELDDRNMEVQRLEALLkamkSECQGQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1408 P----SDKAEAISALSKQHEEQELQLQAQLQELSLKVDALS-------------KEKMSALEQVDHWSNKFS---EWKKK 1467
Cdd:pfam15921  452 AiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLEssertvsdltaslQEKERAIEATNAEITKLRsrvDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1468 AQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNK---KFECLKGEMEVRKSKMEKKECDLETALK---- 1540
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQefki 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1541 ---TQTARVVELE----DCVTQRKKEVESLNETL---KNYNQQRDTEHSGLVQRLQHLEELGEEKD-------NKVREAE 1603
Cdd:pfam15921  612 lkdKKDAKIRELEarvsDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEvlkrnfrNKSEEME 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1604 ETVLRLREHVSSLEAELGTVKKELEHVNSS--------------VKSRDGELKALEDKLELESAAKVELKRKaeqkiaai 1669
Cdd:pfam15921  692 TTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgmqkqITAKRGQIDALQSKIQFLEEAMTNANKE-------- 763

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198995 1670 rKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:pfam15921  764 -KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1918-2160 4.85e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 4.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1918 DRPEENSQSHEIQSNVGTVDGLRSDLESkltgaERDKQKLSKEVARLQKELRALRRE---HQQELDILKRECEQEAEEKL 1994
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALED-----AREQIELLEPIRELAERYAAARERlaeLEYLRAALRLWFAQRRLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1995 KQEQEDLELKHTstlkqlmrefntQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRY 2074
Cdd:COG4913    294 EAELEELRAELA------------RLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRR 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2075 EEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDsvtilELQTQLAqkttlisDSKLKEQELREQVHNLEDRL 2154
Cdd:COG4913    362 AR-LEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE-----ALEEALA-------EAEAALRDLRRELRELEAEI 428


                   ....*.
gi 1907198995 2155 KRYEKN 2160
Cdd:COG4913    429 ASLERR 434
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 674-1706 5.08e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.10  E-value: 5.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  674 QQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQR 753
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  754 RHHQREvgsisEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSA 833
Cdd:pfam01576   82 SRLEEE-----EERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  834 AREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLaQLQDSQLK 913
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAEL-QAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  914 NSTVEKEQARQSLMEKeniilqMREEQAKEIEILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL 993
Cdd:pfam01576  236 AQLAKKEEELQAALAR------LEEETAQKNNALKK-IRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  994 LD--------QEAKLKKELENTVLE--LSQKEKQFNAQILEMAQANSAGISDTVSRLE---------ENQRQQIESLTGA 1054
Cdd:pfam01576  309 EDtldttaaqQELRSKREQEVTELKkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEqakrnkanlEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1055 HQRKLDDV------IEAWEKKLSQQAAELRDKHAE---QMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDV 1125
Cdd:pfam01576  389 LQAELRTLqqakqdSEHKRKKLEGQLQELQARLSEserQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1126 ALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1205
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1206 SCKSLHELSKKSLEDKSLNLKSL----------LEELASQLDSRCERTKAL---------LEAKTNELVCTSRDKADAIL 1266
Cdd:pfam01576  549 RLQRELEALTQQLEEKAAAYDKLektknrlqqeLDDLLVDLDHQRQLVSNLekkqkkfdqMLAEEKAISARYAEERDRAE 628

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1267 ARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEG 1346
Cdd:pfam01576  629 AEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1347 GQQRQAASEKESCITQLKKELAENINAvtllREELSEKKSEiaSLSKQLSDLGAQLESsiSPSDKAEAISALSKqheeqe 1426
Cdd:pfam01576  709 QATEDAKLRLEVNMQALKAQFERDLQA----RDEQGEEKRR--QLVKQVRELEAELED--ERKQRAQAVAAKKK------ 774

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1427 lqLQAQLQELSLKVDALSKEKMSALEQVdhwsnkfsewkKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEE-------Q 1499
Cdd:pfam01576  775 --LELDLKELEAQIDAANKGREEAVKQL-----------KKLQAQMKDLQRELEEARASRDEILAQSKESEKklknleaE 841

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1500 ICLLKEDL---DRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT 1576
Cdd:pfam01576  842 LLQLQEDLaasERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQ 921

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1577 EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREhvssleaELGTVKKELEhvnSSVKSRDGELKALEDKLELES---A 1653
Cdd:pfam01576  922 LTTELAAERSTSQKSESARQQLERQNKELKAKLQE-------MEGTVKSKFK---SSIAALEAKIAQLEEQLEQESrerQ 991

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198995 1654 AKVELKRKAEQKIaairKQLLSQME------EKTQRYAKDTENRLSELSAQLKEREKQV 1706
Cdd:pfam01576  992 AANKLVRRTEKKL----KEVLLQVEderrhaDQYKDQAEKGNSRMKQLKRQLEEAEEEA 1046
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1471-2160 5.71e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 5.71e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1471 RLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELE 1550
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1551 DCVTQRKKEVESLNETLKNYNQQR-----------DTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAE 1619
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEqlrvkekigelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELERE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1620 LGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRkaEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQL 1699
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD--ELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1700 KEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDctHKACKERLCMLQRRLSEKEKLLRRLEQGEG 1779
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE--LYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1780 EARPSQPE-------------------------------AQHRALSGKL---------DCTRARQLEDHVLIGCLPEELE 1819
Cdd:TIGR02169  501 ASEERVRGgraveevlkasiqgvhgtvaqlgsvgeryatAIEVAAGNRLnnvvveddaVAKEAIELLKRRKAGRATFLPL 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1820 EKMKCSLIVSQPMGEETGNNTGV-----KQNWASVVDSV-QKTLQEKELTC---QALEQRVKELESDLVRERGA------ 1884
Cdd:TIGR02169  581 NKMRDERRDLSILSEDGVIGFAVdlvefDPKYEPAFKYVfGDTLVVEDIEAarrLMGKYRMVTLEGELFEKSGAmtggsr 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1885 --HRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVA 1962
Cdd:TIGR02169  661 apRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1963 RLQKELRALRRE---HQQELDILKRECE--QEAEEKLKQEQEDLElkhtstlKQLMREFNTQLAQKEQELERTVQETIDK 2037
Cdd:TIGR02169  741 ELEEDLSSLEQEienVKSELKELEARIEelEEDLHKLEEALNDLE-------ARLSHSRIPEIQAELSKLEEEVSRIEAR 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2038 AQEVEAELLESHQEEtQQLHRKIAEKEDDLRRTARRYEEIlDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSV 2117
Cdd:TIGR02169  814 LREIEQKLNRLTLEK-EYLEKEIQELQEQRIDLKEQIKSI-EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKER 891

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198995 2118 TILE-----LQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2160
Cdd:TIGR02169  892 DELEaqlreLERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 625-1253 7.59e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.38  E-value: 7.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  625 HNKELTALAEQHRTEVEGLQQQQDSLWTERLQ-SLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKL 703
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTKLQQEFNTLESAELRlSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELN 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  704 DKKQMELESVSSELSEALRARDQ----LAEELSVLRGDADKMKQaLEAELEEQRRHHQREVGSISEQQELTVRRaEKALK 779
Cdd:pfam12128  308 GELSAADAAVAKDRSELEALEDQhgafLDADIETAAADQEQLPS-WQSELENLEERLKALTGKHQDVTAKYNRR-RSKIK 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  780 DELSRLGALLDERDEHLRERQARVQDL-EAHLQKSAGELQqalaklDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETE 858
Cdd:pfam12128  386 EQNNRDIAGIKDKLAKIREARDRQLAVaEDDLQALESELR------EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATAT 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  859 KSLLTKQVVEMEThKKHVCEELDAQRAQVQQLERQRSELeekvRSLAQLQDSQLKNSTVEKEQARQSLMEKE-------- 930
Cdd:pfam12128  460 PELLLQLENFDER-IERAREEQEAANAEVERLQSELRQA----RKRRDQASEALRQASRRLEERQSALDELElqlfpqag 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  931 NIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVL- 1009
Cdd:pfam12128  535 TLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALq 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1010 -----------ELSQKEKQFNAQILEMAQANSA--GISDTVSRLEENQRQ---QIESLTGAHQRKLDDVIEAWEKKLSQQ 1073
Cdd:pfam12128  615 sarekqaaaeeQLVQANGELEKASREETFARTAlkNARLDLRRLFDEKQSekdKKNKALAERKDSANERLNSLEAQLKQL 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1074 AAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEEltkEVARLKEAVSGQDVALAGLQGQLEQKSA-----------VIV 1142
Cdd:pfam12128  695 DKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDA---QLALLKAAIAARRSGAKAELKALETWYKrdlaslgvdpdVIA 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1143 SLSERESQLQSQVEKLEADLGCSLSEKLSLQEE--LAELKLLADKSQLR--VSELTGQVQAAEKELQSCKSLHELSKKSL 1218
Cdd:pfam12128  772 KLKREIRTLERKIERIAVRRQEVLRYFDWYQETwlQRRPRLATQLSNIEraISELQQQLARLIADTKLRRAKLEMERKAS 851

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1907198995 1219 EDkslnLKSLLEELASQLDSRCERTKALLEAKTNE 1253
Cdd:pfam12128  852 EK----QQVRLSENLRGLRCEMSKLATLKEDANSE 882
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 838-1076 7.61e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 7.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  838 AGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNST 916
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALeAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  917 VEKEQARQSLMEKENIILQMREEQAKEIEILkqtLSSKEESISILHEEYETKF-KNQEKRMEKIKQKAKEMQETKKKLLD 995
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALL---LSPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  996 QEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgisdtvsrlEENQRQQIESLTGAhQRKLDDVIEAWEKKLSQQAA 1075
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKE---------LAELAAELAELQQE-AEELEALIARLEAEAAAAAE 241


                   .
gi 1907198995 1076 E 1076
Cdd:COG4942    242 R 242
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 726-1357 1.33e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.74  E-value: 1.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  726 QLAEELSVLRGDADKMKQALEAELEEQRRHHQ--REVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARV 803
Cdd:TIGR00618  230 HLREALQQTQQSHAYLTQKREAQEEQLKKQQLlkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  804 QDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAyeEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQ 883
Cdd:TIGR00618  310 QRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRL--LQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  884 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQArqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHE 963
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQL---AHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQES 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  964 EYETK-FKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnAQILEMAQANSAGISDTVSRLEE 1042
Cdd:TIGR00618  465 AQSLKeREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQD--IDNPGPLTRRMQRGEQTYAQLET 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1043 ----------NQRQQIESLTGAHQRKLDDVIEAWEK---------KLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQ 1103
Cdd:TIGR00618  543 seedvyhqltSERKQRASLKEQMQEIQQSFSILTQCdnrskedipNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQ 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1104 SE--KEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEAdlgcsLSEKLSLQEELAELKL 1181
Cdd:TIGR00618  623 PEqdLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLA-----LQKMQSEKEQLTYWKE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1182 LADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCtsrdk 1261
Cdd:TIGR00618  698 MLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTA----- 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1262 ADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQ--------LTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1333
Cdd:TIGR00618  773 ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQeipsdediLNLQCETLVQEEEQFLSRLEEKSATLGEITHQLL 852

                          650       660
                   ....*....|....*....|....
gi 1907198995 1334 GLLTEKEALQQEGGQQRQAASEKE 1357
Cdd:TIGR00618  853 KYEECSKQLAQLTQEQAKIIQLSD 876
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2187-2226 1.56e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.88  E-value: 1.56e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907198995 2187 TEFEYLRKVMFEYMMGRET---KTMAKVITTVLKFPDDQAQKI 2226
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
339-546 1.68e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  339 QRVKRQENLLQRCKETIGSHKEQcALLLSEKEALQEQLD-----ERLQELEKmkgmVITETKRQmletLELKEDEIAQLR 413
Cdd:COG4913    245 EDAREQIELLEPIRELAERYAAA-RERLAELEYLRAALRlwfaqRRLELLEA----ELEELRAE----LARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  414 SHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERlrlqHELSRVRQEAAS 493
Cdd:COG4913    316 ARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASA----EEFAALRAEAAA 391

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907198995  494 MAKNSEEQVAALQKLHAeELASKEQELSRRLEARERELQeqmriALEKSRSEY 546
Cdd:COG4913    392 LLEALEEELEALEEALA-EAEAALRDLRRELRELEAEIA-----SLERRKSNI 438
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 963-1162 1.70e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  963 EEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgISDTVSRLEE 1042
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE-IAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1043 NQRQQIESLTGAHQRKLDDVIE---------------AWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKE 1107
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLAlllspedfldavrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907198995 1108 ELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADL 1162
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
770-1384 2.62e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  770 TVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQ 849
Cdd:COG4913    236 DLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  850 QKVLDLETEKSLLTKQvvemetHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLqdsqLKNSTVEKEQARQSLmek 929
Cdd:COG4913    316 ARLDALREELDELEAQ------IRGNGGDRLEQLEREIERLERELEERERRRARLEAL----LAALGLPLPASAEEF--- 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  930 eniilqmrEEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEnTVL 1009
Cdd:COG4913    383 --------AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALA-EAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1010 ELSQKEKQFNAQILEmaqansagisdtVSRLEENQRQQIESLTGAH-------QRKLDDVIEA-----WEKKLSQQAAEL 1077
Cdd:COG4913    454 GLDEAELPFVGELIE------------VRPEEERWRGAIERVLGGFaltllvpPEHYAAALRWvnrlhLRGRLVYERVRT 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1078 RDKHAEQMEEKEQGLGElrqKVRIVQSE-----KEELTKEVARLK----EAVSGQDVALAgLQGQLEQKSAV----IVSL 1144
Cdd:COG4913    522 GLPDPERPRLDPDSLAG---KLDFKPHPfrawlEAELGRRFDYVCvdspEELRRHPRAIT-RAGQVKGNGTRhekdDRRR 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1145 SERESQL-QSQVEKLEAdlgcslseklsLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSkksleDKSL 1223
Cdd:COG4913    598 IRSRYVLgFDNRAKLAA-----------LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYS-----WDEI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1224 NLKSLLEELASqldsrcertkalLEAKTNELvctsrDKADAILARLSQcqrhtatvgeallrrmgQVSELEAQLTQLTEE 1303
Cdd:COG4913    662 DVASAEREIAE------------LEAELERL-----DASSDDLAALEE-----------------QLEELEAELEELEEE 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1304 QRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSE 1383
Cdd:COG4913    708 LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEE 787


                   .
gi 1907198995 1384 K 1384
Cdd:COG4913    788 E 788
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 334-976 3.67e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 3.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  334 LEMLQQRVKRQENLLQRCKETIGSHKEQCALLlSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLR 413
Cdd:TIGR00618  221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQ-EEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHI 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  414 SHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQmkaveraSEEERLRLQHELSRVRQEAAS 493
Cdd:TIGR00618  300 KAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLH-------SQEIHIRDAHEVATSIREISC 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  494 MAKNSEEQVAALQKlHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKA-IL 572
Cdd:TIGR00618  373 QQHTLTQHIHTLQQ-QKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITcTA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  573 TESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLE-AEKNKHNKELTALAEQHRTEVEGLQQQQDSLw 651
Cdd:TIGR00618  452 QCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLElQEEPCPLCGSCIHPNPARQDIDNPGPLTRRM- 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  652 tERLQSLSQQHQAAVEELREKYQQEKD--ALLKEKESLFQAHIQDMNEK---TLEKLDKKQMELESVSSELSEALRARDQ 726
Cdd:TIGR00618  531 -QRGEQTYAQLETSEEDVYHQLTSERKqrASLKEQMQEIQQSFSILTQCdnrSKEDIPNLQNITVRLQDLTEKLSEAEDM 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  727 LAEELSVLrgdadkMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDE--HLRERQARVQ 804
Cdd:TIGR00618  610 LACEQHAL------LRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPkeLLASRQLALQ 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  805 DLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQR 884
Cdd:TIGR00618  684 KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAH 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  885 AQ------------------VQQLERQRSELEEKVRSLAQLQ---------DSQLKNSTVEK-----EQARQSLMEKENI 932
Cdd:TIGR00618  764 FNnneevtaalqtgaelshlAAEIQFFNRLREEDTHLLKTLEaeigqeipsDEDILNLQCETlvqeeEQFLSRLEEKSAT 843

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 1907198995  933 ILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRM 976
Cdd:TIGR00618  844 LGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 661-1020 4.38e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.97  E-value: 4.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  661 QHQAAVEElreKYQQEKdallkeKESLFQAHIQDMNEKTLEKLDKKQmelesvssELSEALRARDQLAEELSVLRGDADK 740
Cdd:pfam17380  279 QHQKAVSE---RQQQEK------FEKMEQERLRQEKEEKAREVERRR--------KLEEAEKARQAEMDRQAAIYAEQER 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  741 MKQALEAELEEQRRHHQREVGSISEQQELTVrraEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQA 820
Cdd:pfam17380  342 MAMERERELERIRQEERKRELERIRQEEIAM---EISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQ 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  821 LAKLDLLHSEQSAAReqagayeeqlaqmQQKVLDLETEKSLLTKQVVEMETHKKHVCEELdaqRAQVQQLERQRSELEEK 900
Cdd:pfam17380  419 KVEMEQIRAEQEEAR-------------QREVRRLEEERAREMERVRLEEQERQQQVERL---RQQEEERKRKKLELEKE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  901 VRSLAQLQDSQLKNSTVEKEQARQSLMEKENiilqMREEQAKEIeilkqtlsskEESISILHEEYETKFKNQEKRMEKIK 980
Cdd:pfam17380  483 KRDRKRAEEQRRKILEKELEERKQAMIEEER----KRKLLEKEM----------EERQKAIYEEERRREAEEERRKQQEM 548

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1907198995  981 QKAKEMQETKKKLLDQEAKL-----KKELENTVLELSQKEKQFNA 1020
Cdd:pfam17380  549 EERRRIQEQMRKATEERSRLeamerEREMMRQIVESEKARAEYEA 593
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
968-1569 4.76e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 4.76e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  968 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnaqilemaqansagisdtVSRLEENQRQQ 1047
Cdd:PRK03918   159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLRE-------------------INEISSELPEL 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1048 IESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKeqgLGELRQKVRIVQSEKEELTKEVARLKEaVSGQDVAL 1127
Cdd:PRK03918   220 REELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEK---IRELEERIEELKKEIEELEEKVKELKE-LKEKAEEY 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1128 AGLQGQLEQKSAVIVSLSERESQLQSQVEKLEAdlgcSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSC 1207
Cdd:PRK03918   296 IKLSEFYEEYLDELREIEKRLSRLEEEINGIEE----RIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKK 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1208 KSLHELSKKSLEDKSLNLKSLLEELasqldsrcERTKALLEAKTNElvctsrdkadaILARLSQCQRHTATVGEALLRRM 1287
Cdd:PRK03918   372 EELERLKKRLTGLTPEKLEKELEEL--------EKAKEEIEEEISK-----------ITARIGELKKEIKELKKAIEELK 432

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1288 GQVSELEAQLTQLTEEQRtlKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEscITQLKKEL 1367
Cdd:PRK03918   433 KAKGKCPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKE--LAEQLKEL 508

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1368 AENINAVTLlrEELSEKKSEIASLSKQLSDLGAQLESSispSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEK 1447
Cdd:PRK03918   509 EEKLKKYNL--EELEKKAEEYEKLKEKLIKLKGEIKSL---KKELEKLEELKKKLAELEKKLDELEEELAELLKELEELG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1448 MSALEQVDHWSNKFSEWKKKaQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRK-S 1526
Cdd:PRK03918   584 FESVEELEERLKELEPFYNE-YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyE 662

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907198995 1527 KMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKN 1569
Cdd:PRK03918   663 ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
770-1254 4.92e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 4.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  770 TVRRAEKALKDELSRLG---ALLDERDEHLRERQARVQDLEAHLQKSAGELQQA---LAKLDLLHSEQSAAREQAGAYEE 843
Cdd:PRK03918   173 EIKRRIERLEKFIKRTEnieELIKEKEKELEEVLREINEISSELPELREELEKLekeVKELEELKEEIEELEKELESLEG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  844 QLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVcEELDAQRAQVQQLERQRSELEEKVRSLAQLQD--SQLKNSTVEKEQ 921
Cdd:PRK03918   253 SKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYIKLSEFYEEYLDELREIEKRLSrlEEEINGIEERIK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  922 ARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK 1001
Cdd:PRK03918   332 ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKIT 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1002 KELENTVLELSQKEKQFNA---------------------QILEMAQANSAGISDTVSRLEENQRQQIESLTGAH----- 1055
Cdd:PRK03918   412 ARIGELKKEIKELKKAIEElkkakgkcpvcgrelteehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEkvlkk 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1056 ------QRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSE---KEELTKEVARLKEAVSGQDVA 1126
Cdd:PRK03918   492 eselikLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKElekLEELKKKLAELEKKLDELEEE 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1127 LAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQS 1206
Cdd:PRK03918   572 LAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907198995 1207 CKSL-----HELSKKSLEDKSLNLKSLLEELaSQLDSRCERTKALLEAKTNEL 1254
Cdd:PRK03918   652 LEKKyseeeYEELREEYLELSRELAGLRAEL-EELEKRREEIKKTLEKLKEEL 703
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 920-1063 6.43e-05

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 48.12  E-value: 6.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  920 EQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAK 999
Cdd:pfam10168  553 DLAREEIQKRVKLLKLQKEQQLQELQSLEEERKSLSERAEKLAEKYEEIKDKQEKLMRRCKKVLQRLNSQLPVLSDAERE 632

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198995 1000 LKKELE--NTVLE-----LSQKEKQFNAQILEMAQANSAGISDTVSrLEENQRQQIESLTGAHQRKLDDVI 1063
Cdd:pfam10168  633 MKKELEtiNEQLKhlanaIKQAKKKMNYQRYQIAKSQSIRKKSSLS-LSEKQRKTIKEILKQLGSEIDELI 702
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
711-908 6.45e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 6.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  711 ESVSSELSEALRARDQLAEELSVLRGDADkmkqALEAELEEQRRHHQreVGSISEQQELTVRRaekalkdeLSRLGALLD 790
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELE----EAEAALEEFRQKNG--LVDLSEEAKLLLQQ--------LSELESQLA 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  791 ERDEHLRERQARVQDLEAHLQKSAGE---------LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSL 861
Cdd:COG3206    230 EARAELAEAEARLAALRAQLGSGPDAlpellqspvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQ 309

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198995  862 LTKQVVEMETHkkhvceELDAQRAQVQQLERQRSELEEKVRSLAQLQ 908
Cdd:COG3206    310 EAQRILASLEA------ELEALQAREASLQAQLAQLEARLAELPELE 350
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
663-810 7.54e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.93  E-value: 7.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  663 QAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEElsvlrgdadkmk 742
Cdd:COG2433    379 EEALEELIEKELPEEEPEAEREKEHEERELTEEEEE-IRRLEEQVERLEAEVEELEAELEEKDERIER------------ 445

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198995  743 qaLEAELEEQRRhhqrevgsiSEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHL 810
Cdd:COG2433    446 --LERELSEARS---------EERREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELW 502
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
776-1063 8.04e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.20  E-value: 8.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  776 KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 855
Cdd:COG4372     48 EQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  856 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQ-DSQLKNSTVEKEQARQSLMEKENIIL 934
Cdd:COG4372    128 EQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEaEQALDELLKEANRNAEKEEELAEAEK 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  935 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQK 1014
Cdd:COG4372    208 LIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEA 287

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1907198995 1015 EKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVI 1063
Cdd:COG4372    288 LEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILL 336
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1958-2169 8.68e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 8.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1958 SKEVARLQKELRALRREHQQELDILKREceQEAEEKLKQEQEDLELKhTSTLKQLMREFNTQLAQKEQELERT------V 2031
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAAL--KKEEKALLKQLAALERR-IAALARRIRALEQELAALEAELAELekeiaeL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2032 QETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARR---YEEILDAREEEMTG------KVTDLQTQLEELQKK 2102
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARREQAEElradlaELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198995 2103 YQQRLEQEESTKDSVT--ILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKNACAATVGTP 2169
Cdd:COG4942    176 LEALLAELEEERAALEalKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 709-925 9.35e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.13  E-value: 9.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  709 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQEltvrraekALKDELSRLGAL 788
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYN-ELQAELEALQAEIDKLQAEIA--------EAEAEIEERREE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  789 LDERDEHLRERQARVQDLEAHLqkSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVE 868
Cdd:COG3883     88 LGERARALYRSGGSVSYLDVLL--GSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAE 165

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907198995  869 METHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 925
Cdd:COG3883    166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1138-1369 9.47e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1138 SAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKS 1217
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1218 LEDKSLNLKSLLeeLASQLDSRCERTKALLEAKtnelvctSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQL 1297
Cdd:COG4942     99 LEAQKEELAELL--RALYRLGRQPPLALLLSPE-------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907198995 1298 TQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEgllTEKEALQQEGGQQRQAASEKESCITQLKKELAE 1369
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARLEAEAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 697-911 9.63e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  697 EKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQ---ALEAELEEQRRHHQREVGSISEQQELTVRR 773
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQelaALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  774 AEKALK-DELSRLGALLDERD-EHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAgayEEQLAQMQQK 851
Cdd:COG4942    110 LRALYRlGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL---EALLAELEEE 186

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  852 VLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQ 911
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
mukB PRK04863
chromosome partition protein MukB;
660-925 1.06e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  660 QQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALR-------ARDQLAEE 730
Cdd:PRK04863   847 VELERALADHESQEQQQRSQLeqAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRfvqqhgnALAQLEPI 926

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  731 LSVLRGDadkmkqalEAELEEQRRHHQRevgsiSEQQELTVRRAEKALKDelsrlgalLDERDEHLRERQArVQDLEAhl 810
Cdd:PRK04863   927 VSVLQSD--------PEQFEQLKQDYQQ-----AQQTQRDAKQQAFALTE--------VVQRRAHFSYEDA-AEMLAK-- 982

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  811 qksAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEME------------------- 870
Cdd:PRK04863   983 ---NSDLNEKLrQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKqelqdlgvpadsgaeerar 1059

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907198995  871 THKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 925
Cdd:PRK04863  1060 ARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNA 1114
PRK12704 PRK12704
phosphodiesterase; Provisional
 1954-2085 1.13e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.08  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1954 KQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNtQLAQKEQELERtvqe 2033
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK-RLLQKEENLDR---- 100

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907198995 2034 tidkaqevEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEM 2085
Cdd:PRK12704   101 --------KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
171-838 1.18e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  171 PSDMESEAEDAPWNSDGLSR-EQLLQRLRRMERSLS---SYRGKYSELVTAFQTLQREKKKLQGILSQSQDKSLR-RISE 245
Cdd:COG4913    220 EPDTFEAADALVEHFDDLERaHEALEDAREQIELLEpirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEaELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  246 LREELQMDQQAKKHLQDEFDACLEEKDQyisvlqtqvsLLKQRLQNGPMNVDapkplppgELQAEVHGDTEKmegvgepv 325
Cdd:COG4913    300 LRAELARLEAELERLEARLDALREELDE----------LEAQIRGNGGDRLE--------QLEREIERLERE-------- 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  326 gggtsaktLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITEtKRQMLETLELK 405
Cdd:COG4913    354 --------LEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA-LRDLRRELREL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  406 EDEIAQLRSHIKQMTTQGEELReqkekseraafEELEKALSTAQ------------KTEDAQRRMKMEM----------- 462
Cdd:COG4913    425 EAEIASLERRKSNIPARLLALR-----------DALAEALGLDEaelpfvgelievRPEEERWRGAIERvlggfaltllv 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  463 -DEQMKAVERASEEERLRLQHELSRVRQEAAsmaknSEEQVAALQKLHAEELASKEQELSRRLEAR------------ER 529
Cdd:COG4913    494 pPEHYAAALRWVNRLHLRGRLVYERVRTGLP-----DPERPRLDPDSLAGKLDFKPHPFRAWLEAElgrrfdyvcvdsPE 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  530 EL-QEQMRIALE---KSRSEylklTQEKEQQESLALE----ELELQKKAILtesENKLQELGQEAEAYRTRILELETSLE 601
Cdd:COG4913    569 ELrRHPRAITRAgqvKGNGT----RHEKDDRRRIRSRyvlgFDNRAKLAAL---EAELAELEEELAEAEERLEALEAELD 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  602 kSLQESKTQSEHLAVHLEAEKNkhnkeltalAEQHRTEVEGLQQQQDSLWTE--RLQSLSQQHQAAVEELREkYQQEKDA 679
Cdd:COG4913    642 -ALQERREALQRLAEYSWDEID---------VASAEREIAELEAELERLDASsdDLAALEEQLEELEAELEE-LEEELDE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  680 LLKEKESLFQAHIQdmnekTLEKLDKKQMELESVSSELSEALRARdqLAEELSVLRGDADkmKQALEAELEEQRRHHQRE 759
Cdd:COG4913    711 LKGEIGRLEKELEQ-----AEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAV--ERELRENLEERIDALRAR 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  760 VGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQA-RVQDLEAHLQKSAGEL-QQALAKLDLLHSEQSAAREQ 837
Cdd:COG4913    782 LNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRlEEDGLPEYEERFKELLnENSIEFVADLLSKLRRAIRE 861


                   .
gi 1907198995  838 A 838
Cdd:COG4913    862 I 862
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 444-668 1.65e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  444 ALSTAQKTEDAQRRMKmEMDEQMKAVER---ASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAE--ELASKEQ 518
Cdd:COG4942     15 AAAQADAAAEAEAELE-QLQQEIAELEKelaALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElaELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  519 ELSRRLEARERELQEQMRIALEKSRSEYLK--LTQEKEQQESLALEELELQKKAILTESEnKLQELGQEAEAYRTRILEL 596
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPLAllLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRADLAELAALRAELEAE 172

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907198995  597 ETSLEKSLQESKTQSEHLAVhLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVEE 668
Cdd:COG4942    173 RAELEALLAELEEERAALEA-LKAERQKLLARLEKELAELAAELAELQQEAEEL-EALIARLEAEAAAAAER 242
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 714-874 1.72e-04

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 45.90  E-value: 1.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  714 SSELSEALRARDQLAEELSVLRGDAdkmkQALEAELEEQRRHHQREVGSISEQ------QELTVRRAEKALKDELSRLGA 787
Cdd:pfam09787   46 TLELEELRQERDLLREEIQKLRGQI----QQLRTELQELEAQQQEEAESSREQlqeleeQLATERSARREAEAELERLQE 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  788 LLDERDEHLRE----RQARVQDLEAHLQKSAGELQQAlaklDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLT 863
Cdd:pfam09787  122 ELRYLEEELRRskatLQSRIKDREAEIEKLRNQLTSK----SQSSSSQSELENRLHQLTETLIQKQTMLEALSTEKNSLV 197

                          170
                   ....*....|.
gi 1907198995  864 KQVVEMETHKK 874
Cdd:pfam09787  198 LQLERMEQQIK 208
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
436-908 1.98e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  436 AAFEELEKALSTAQKTEDAQRRMKMEMDEqmkaveraSEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAEELAS 515
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEELEE--------LEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  516 KEQELSRRLEARERELQEQMRiALEKSRSEYlkltQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILE 595
Cdd:COG4717    143 ELPERLEELEERLEELRELEE-ELEELEAEL----AELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEE 217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  596 LETSLEkSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQ 675
Cdd:COG4717    218 AQEELE-ELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLARE 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  676 EKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSseLSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRH 755
Cdd:COG4717    297 KASLGKEAEELQALPALEELEEEELEELLAALGLPPDLS--PEELLELLDRIEELQELLREAEELEEELQLEELEQEIAA 374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  756 HQREVGSISEqqeltvrraekalkDELSRLGalldERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDL--LHSEQSA 833
Cdd:COG4717    375 LLAEAGVEDE--------------EELRAAL----EQAEEYQELKEELEELEEQLEELLGELEELLEALDEeeLEEELEE 436

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198995  834 AREQAGAYEEQLAQMQQKVLDLETEKSLLTKQvvemethkkhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQ 908
Cdd:COG4717    437 LEEELEELEEELEELREELAELEAELEQLEED------------GELAELLQELEELKAELRELAEEWAALKLAL 499
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
332-766 2.39e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 2.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  332 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCAL--LLSEKEALQEQLDERLQELEKMKGMVitETKRQMLETLELKEDEI 409
Cdd:COG4717     95 EELEELEEELEELEAELEELREELEKLEKLLQLlpLYQELEALEAELAELPERLEELEERL--EELRELEEELEELEAEL 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  410 AQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERL--RLQHELSRV 487
Cdd:COG4717    173 AELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALeeRLKEARLLL 252

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  488 RQEAA--------SMAKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIAlEKSRSEYLKLTQEKEQQESL 559
Cdd:COG4717    253 LIAAAllallglgGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALP-ALEELEEEELEELLAALGLP 331

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  560 ALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEhlavhleaeknkhnKELTALAEQHRTE 639
Cdd:COG4717    332 PDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDE--------------EELRAALEQAEEY 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  640 VEglqqqqdslWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKT---LEKLDKKQMELESVSS- 715
Cdd:COG4717    398 QE---------LKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELeelREELAELEAELEQLEEd 468

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907198995  716 -ELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ 766
Cdd:COG4717    469 gELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLER 520
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
775-1242 2.60e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 2.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  775 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQ--KV 852
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKllQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  853 LDLETEKSLLTKQVVEMETHKkhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKeni 932
Cdd:COG4717    128 LPLYQELEALEAELAELPERL----EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE--- 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  933 ilqmREEQAKEIEILKQTLSSKEESISILHEEYETkfknqekrmekiKQKAKEMQETKKKLldQEAKLKKELENTVLELS 1012
Cdd:COG4717    201 ----LEELQQRLAELEEELEEAQEELEELEEELEQ------------LENELEAAALEERL--KEARLLLLIAAALLALL 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1013 QKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGL 1092
Cdd:COG4717    263 GLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLEL 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1093 GELRQKVRIVQSEKEELTKEvARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSL 1172
Cdd:COG4717    343 LDRIEELQELLREAEELEEE-LQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907198995 1173 QEELAELKLLADKSQLR--VSELTGQVQAAEKELQSCKslHELSKKSLEDKSLNLKSLLEELASQLDSRCER 1242
Cdd:COG4717    422 LEALDEEELEEELEELEeeLEELEEELEELREELAELE--AELEQLEEDGELAELLQELEELKAELRELAEE 491
PLN02939 PLN02939
transferase, transferring glycosyl groups
 775-998 2.64e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.43  E-value: 2.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  775 EKALKDELSRLGALLDERDEHLR---ERQARVQDLEAHLQKSAGELQQALA-----------KLDLLHSEQSAAREQAGA 840
Cdd:PLN02939   165 KEALQGKINILEMRLSETDARIKlaaQEKIHVEILEEQLEKLRNELLIRGAteglcvhslskELDVLKEENMLLKDDIQF 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  841 YEEQLAQMQ---QKVLDLETEKSLLTKQVVEMEthkkhvCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSqlknSTV 917
Cdd:PLN02939   245 LKAELIEVAeteERVFKLEKERSLLDASLRELE------SKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDR----ATN 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  918 EKEQARQSLMEKENI--ILQMREEQAKE----------IEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKE 985
Cdd:PLN02939   315 QVEKAALVLDQNQDLrdKVDKLEASLKEanvskfssykVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSK 394

                          250
                   ....*....|....
gi 1907198995  986 M-QETKKKLLDQEA 998
Cdd:PLN02939   395 LkEESKKRSLEHPA 408
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 892-1717 2.87e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.32  E-value: 2.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  892 RQRSELEEKVRSLAQLQDSQLK--NSTVEKEQARQSLMEKENII---LQMREEQAKEIEILKQTLSSKEESISILHEEYE 966
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKaeSELKELEKKHQQLCEEKNALqeqLQAETELCAEAEEMRARLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  967 TKFKNQEKRMEKIKQKAKEMQETKKKL---LDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSA----------GI 1033
Cdd:pfam01576   82 SRLEEEEERSQQLQNEKKKMQQHIQDLeeqLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKlskerklleeRI 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1034 SDTVSRL--EENQRQQIESLTGAHQRKLDDV-------------IEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQK 1098
Cdd:pfam01576  162 SEFTSNLaeEEEKAKSLSKLKNKHEAMISDLeerlkkeekgrqeLEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKK 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1099 vrivqseKEELTKEVARLKEAVSGQDVALAGLQgQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSeklSLQEELAE 1178
Cdd:pfam01576  242 -------EEELQAALARLEEETAQKNNALKKIR-ELEAQISELQEDLESERAARNKAEKQRRDLGEELE---ALKTELED 310

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1179 LKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSlnlKSLLEELASQLD------SRCERTKALLEAKTN 1252
Cdd:pfam01576  311 TLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKH---TQALEELTEQLEqakrnkANLEKAKQALESENA 387

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1253 ELVCTSRDKADAILARLSQCQRHTATVGEALLRrmgqVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKE-KQIKTMK-- 1329
Cdd:pfam01576  388 ELQAELRTLQQAKQDSEHKRKKLEGQLQELQAR----LSESERQRAELAEKLSKLQSELESVSSLLNEAEgKNIKLSKdv 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1330 ADIEGLLTEKEALQQEGGQQRQAASEK----ESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESS 1405
Cdd:pfam01576  464 SSLESQLQDTQELLQEETRQKLNLSTRlrqlEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAL 543

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1406 ISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQ 1485
Cdd:pfam01576  544 EEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEE 623

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1486 LDVKATDAREKE----------EQICLLKEDLDRQNKKfecLKGEMEVRKS----------KMEKKECDLETALKTQTAR 1545
Cdd:pfam01576  624 RDRAEAEAREKEtralslaralEEALEAKEELERTNKQ---LRAEMEDLVSskddvgknvhELERSKRALEQQVEEMKTQ 700

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1546 VVELEDCVTQRKKEVESLNETLKNYNQQRDTEhsglvqrLQHLEELGEEKDNKvreaeetvlrLREHVSSLEAELGTVKK 1625
Cdd:pfam01576  701 LEELEDELQATEDAKLRLEVNMQALKAQFERD-------LQARDEQGEEKRRQ----------LVKQVRELEAELEDERK 763

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1626 ELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAeqkiaairKQLLSQMEEkTQRYAKDTENRLSELSAQLKEREKQ 1705
Cdd:pfam01576  764 QRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQL--------KKLQAQMKD-LQRELEEARASRDEILAQSKESEKK 834

                          890
                   ....*....|..
gi 1907198995 1706 VHSLEDKLKNLE 1717
Cdd:pfam01576  835 LKNLEAELLQLQ 846
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 342-687 2.88e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.21  E-value: 2.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  342 KRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRqmletLELKEDEIAQLRSHIKQMTT 421
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKE-----IEQLEQEEEKLKERLEELEE 744

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  422 QGEELrEQKEKSERAAFEELEKALstaqkteDAQRRMKMEMDEQMKAVERASEEERLR-LQHELSRVRQEAASMAKNSEE 500
Cdd:TIGR02169  745 DLSSL-EQEIENVKSELKELEARI-------EELEEDLHKLEEALNDLEARLSHSRIPeIQAELSKLEEEVSRIEARLRE 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  501 QVAALQKLHAEElaSKEQELSRRLEARERELQEQmrIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQ 580
Cdd:TIGR02169  817 IEQKLNRLTLEK--EYLEKEIQELQEQRIDLKEQ--IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERD 892

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  581 ELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQ 660
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEP 972

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1907198995  661 QHQAAVEELRE------KYQQEKDALLKEKESL 687
Cdd:TIGR02169  973 VNMLAIQEYEEvlkrldELKEKRAKLEEERKAI 1005
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1171-1411 3.30e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1171 SLQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckslhelskKSLEDKSLNLKSLLEELASQLDSRcERTKALLEAK 1250
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQL-----------AALERRIAALARRIRALEQELAAL-EAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1251 TNELVCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLT---QLTEEQRTLKSSFQQVTNQLEEKEKQIKT 1327
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1328 MKADIEGLLTEKEALQQEggqQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSIS 1407
Cdd:COG4942    172 ERAELEALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ....
gi 1907198995 1408 PSDK 1411
Cdd:COG4942    249 AALK 252
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 368-616 3.53e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.88  E-value: 3.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  368 EKEALQEQLDERLQELEKMKGMVITETKRQMLEtLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALST 447
Cdd:pfam17380  347 ERELERIRQEERKRELERIRQEEIAMEISRMRE-LERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQI 425

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  448 AQKTEDA-QRRMKMEMDEQMKAVERASEEERLRlQHELSRVRQ-EAASMAKNSEEQVAALQKLHAEELASK--EQELSRR 523
Cdd:pfam17380  426 RAEQEEArQREVRRLEEERAREMERVRLEEQER-QQQVERLRQqEEERKRKKLELEKEKRDRKRAEEQRRKilEKELEER 504

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  524 LEARERElqEQMRIALEKSRSEYLKLTQEKEQQeslaLEELELQKKAILTESENKLQELGQEAEAYRTRI--LELETSLE 601
Cdd:pfam17380  505 KQAMIEE--ERKRKLLEKEMEERQKAIYEEERR----REAEEERRKQQEMEERRRIQEQMRKATEERSRLeaMEREREMM 578

                          250
                   ....*....|....*
gi 1907198995  602 KSLQESKTQSEHLAV 616
Cdd:pfam17380  579 RQIVESEKARAEYEA 593
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 708-818 3.86e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 45.84  E-value: 3.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  708 MELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEltvrrAEKALKDELSRLGA 787
Cdd:COG0542    404 MEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWE-----AEKELIEEIQELKE 478

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1907198995  788 LLDERDEHLRERQARVQDLEAHLQKSAGELQ 818
Cdd:COG0542    479 ELEQRYGKIPELEKELAELEEELAELAPLLR 509
PTZ00121 PTZ00121
MAEBL; Provisional
 308-718 3.95e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.90  E-value: 3.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  308 QAEVHGDTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMK 387
Cdd:PTZ00121  1529 KAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK 1608

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  388 GMVITETKRQMLETLELKEDE-----IAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQrrmKMEM 462
Cdd:PTZ00121  1609 AEEAKKAEEAKIKAEELKKAEeekkkVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK---KAEE 1685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  463 DEQMKAVERASEEERLRLQHELSRVRQEaasmaknseeqvaalQKLHAEELASKEQELSRRLEARERELQEqmrialEKS 542
Cdd:PTZ00121  1686 DEKKAAEALKKEAEEAKKAEELKKKEAE---------------EKKKAEELKKAEEENKIKAEEAKKEAEE------DKK 1744

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  543 RSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRtrilelETSLEKSLQESKTQSEHLavhleAEK 622
Cdd:PTZ00121  1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKR------RMEVDKKIKDIFDNFANI-----IEG 1813

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  623 NKHNKELTALAEQhrTEVEGLQQQQDSLWTERLQSLS-QQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLE 701
Cdd:PTZ00121  1814 GKEGNLVINDSKE--MEDSAIKEVADSKNMQLEEADAfEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIE 1891

                          410
                   ....*....|....*..
gi 1907198995  702 KLDKKQMELESVSSELS 718
Cdd:PTZ00121  1892 KIDKDDIEREIPNNNMA 1908
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1930-2121 4.03e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 4.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1930 QSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTL 2009
Cdd:COG3206    204 KNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELS 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2010 KQL------MREFNTQLAQKEQELERTVQETIDKAqEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEIldAREe 2083
Cdd:COG3206    284 ARYtpnhpdVIALRAQIAALRAQLQQEAQRILASL-EAELEALQAREASLQAQLAQLEARLAELPELEAELRRL--ERE- 359

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1907198995 2084 emtgkVTDLQTQLEELQKKYQQRLEQEESTKDSVTILE 2121
Cdd:COG3206    360 -----VEVARELYESLLQRLEEARLAEALTVGNVRVID 392
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1227-1403 4.18e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1227 SLLEELASQLDS-RCERTKALLEAKTNELvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELE-AQLTQLTEEQ 1304
Cdd:COG4913    272 AELEYLRAALRLwFAQRRLELLEAELEEL----RAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREI 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1305 RTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitQLKKELAENINAVTLLREELSEK 1384
Cdd:COG4913    348 ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE---ALEEALAEAEAALRDLRRELREL 424

                          170
                   ....*....|....*....
gi 1907198995 1385 KSEIASLSKQLSDLGAQLE 1403
Cdd:COG4913    425 EAEIASLERRKSNIPARLL 443
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1480-2159 4.63e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 45.73  E-value: 4.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1480 KDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV--RKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1557
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEeeKEKKLQEEELKLLAKEEEELKSELLKLERRKVDD 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1558 KEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSR 1637
Cdd:pfam02463  313 EEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1638 DGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQmEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:pfam02463  393 KEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEI-LEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1718 SSPHPEVPAVSRSMQSVAASPEQEAPDSQDCThkACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKL 1797
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKES--KARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1798 DCTRAR-QLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELES 1876
Cdd:pfam02463  550 IVEVSAtADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGIL 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1877 DLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK 1956
Cdd:pfam02463  630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1957 LSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNtqlaQKEQELERTVQETID 2036
Cdd:pfam02463  710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELS----LKEKELAEEREKTEK 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2037 KAQEVEAELLESHQEETqqlhrkIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDS 2116
Cdd:pfam02463  786 LKVEEEKEEKLKAQEEE------LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL 859

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|...
gi 1907198995 2117 VTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEK 2159
Cdd:pfam02463  860 EEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEL 902
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1058-1718 5.04e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 45.35  E-value: 5.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1058 KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQK 1137
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1138 SAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKS 1217
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1218 LEDKSLNLKSLLEELASQLDSRCERTKALLEAKtnelvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQL 1297
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEEEE--------EELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1298 TQLTEEQRTLKSSfQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLL 1377
Cdd:pfam02463  398 ELKSEEEKEAQLL-LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1378 REELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLkVDALSKEKMSALEQVDHW 1457
Cdd:pfam02463  477 TQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVA-VENYKVAISTAVIVEVSA 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1458 SNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLET 1537
Cdd:pfam02463  556 TADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELT 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1538 ALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHsglVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLE 1617
Cdd:pfam02463  636 KLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELL---EIQELQEKAESELAKEEILRRQLEIKKKEQREKEEL 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1618 AELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSA 1697
Cdd:pfam02463  713 KKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEK 792

                          650       660
                   ....*....|....*....|.
gi 1907198995 1698 QLKEREKQVHSLEDKLKNLES 1718
Cdd:pfam02463  793 EEKLKAQEEELRALEEELKEE 813
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1955-2156 5.67e-04

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 45.07  E-value: 5.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1955 QKLSKEVARLQKELRALR---REHQQELDILKRECEQEAEEKLKQ-EQEDLE-----LKHTSTLKQLMREFNTQLAQKEQ 2025
Cdd:COG0497    161 REAYRAWRALKKELEELRadeAERARELDLLRFQLEELEAAALQPgEEEELEeerrrLSNAEKLREALQEALEALSGGEG 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2026 ELERTVQETIDKAQEVE---------AELLESHQEETQqlhrkiaekedDLRRTARRYEEILDAREEEMTgKVTDLQTQL 2096
Cdd:COG0497    241 GALDLLGQALRALERLAeydpslaelAERLESALIELE-----------EAASELRRYLDSLEFDPERLE-EVEERLALL 308

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2097 EELQKKYQQRLEQeestkdsvtILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKR 2156
Cdd:COG0497    309 RRLARKYGVTVEE---------LLAYAEELRAELAELENSDERLEELEAELAEAEAELLE 359
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 191-851 6.05e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 6.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  191 EQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSQDkslrRISELREELQMDQQAKKHLQDEFDACLEE 270
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE----ELEDLRAELEEVDKEFAETRDELKDYREK 393

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  271 KDQYIS---VLQTQVSLLKQRLQNGPMNVdapkplppGELQAEVHGDTEKMEGvgepvgggtSAKTLEMLQQRVKRQENL 347
Cdd:TIGR02169  394 LEKLKReinELKRELDRLQEELQRLSEEL--------ADLNAAIAGIEAKINE---------LEEEKEDKALEIKKQEWK 456

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  348 LQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKG--MVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEE 425
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAqaRASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGER 536

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  426 LREQKE--KSERAAFEELEKALSTAQKTEDAQRRM----------KM-----------------------EMDEQMKA-- 468
Cdd:TIGR02169  537 YATAIEvaAGNRLNNVVVEDDAVAKEAIELLKRRKagratflplnKMrderrdlsilsedgvigfavdlvEFDPKYEPaf 616

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  469 ---------VERASEEERLRLQHELSRVRQE---------AASMAKNSEEQVAALQKLHAEELASKEQELSRRLEA--RE 528
Cdd:TIGR02169  617 kyvfgdtlvVEDIEAARRLMGKYRMVTLEGElfeksgamtGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSlqSE 696

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  529 RELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQkKAILTESENKLQELGQEAEAYRTRILELETSLEKsLQESK 608
Cdd:TIGR02169  697 LRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL-KERLEELEEDLSSLEQEIENVKSELKELEARIEE-LEEDL 774

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  609 TQSEHLAVHLEAEKNKHN-KELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKyqQEKDALLKEKESL 687
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREI-EQKLNRLTLEKEYLEKEIQEL--QEQRIDLKEQIKS 851

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  688 FQAHIQDMN---EKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadKMKQALEAELEEQRRHHQREVGSIS 764
Cdd:TIGR02169  852 IEKEIENLNgkkEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELE----RKIEELEAQIEKKRKRLSELKAKLE 927

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  765 EQQElTVRRAEKALKDELSRLGALLDERD--EHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYE 842
Cdd:TIGR02169  928 ALEE-ELSEIEDPKGEDEEIPEEELSLEDvqAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006


                   ....*....
gi 1907198995  843 EQLAQMQQK 851
Cdd:TIGR02169 1007 ERIEEYEKK 1015
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1534-2076 6.17e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 6.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1534 DLETALKTQTArvvELEDCVTQRKKEVESLNETlknynQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHV 1613
Cdd:PRK02224   210 GLESELAELDE---EIERYEEQREQARETRDEA-----DEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEV 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1614 SSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIrKQLLSQMEEKTQRyAKDTENRLS 1693
Cdd:PRK02224   282 RDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAA-QAHNEEAESLRED-ADDLEERAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1694 ELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQeaPDSQDCTHKACKERLCMLQRRLSEKEKLLRR 1773
Cdd:PRK02224   360 ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD--LGNAEDFLEELREERDELREREAELEATLRT 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1774 LEQGEGEARPSQPEaqhralsGKldCTRARQ-LEDHVLIGCLPEELEEKMKCSLIVSQPmgEETGNNTGVKQNWASVVDS 1852
Cdd:PRK02224   438 ARERVEEAEALLEA-------GK--CPECGQpVEGSPHVETIEEDRERVEELEAELEDL--EEEVEEVEERLERAEDLVE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1853 VQKTLQEKELTCQALEQRVKElesdlvrergaHRLEVEKLTLKYEKSQSSQQEMDGEnkCVEVLEDRPEENSQSHEIQSN 1932
Cdd:PRK02224   507 AEDRIERLEERREDLEELIAE-----------RRETIEEKRERAEELRERAAELEAE--AEEKREAAAEAEEEAEEAREE 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1933 VGTVDGLRSDLESKLTGAERDKQKLSK-EVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 2011
Cdd:PRK02224   574 VAELNSKLAELKERIESLERIRTLLAAiADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEARE 653

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198995 2012 LMREFNTQLAQKEQELERTVQETIDKAQEVEAelLESHQEETQQLHRKIAEKEDDLRRTARRYEE 2076
Cdd:PRK02224   654 DKERAEEYLEQVEEKLDELREERDDLQAEIGA--VENELEELEELRERREALENRVEALEALYDE 716
mukB PRK04863
chromosome partition protein MukB;
361-989 6.90e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.95  E-value: 6.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  361 QCALLLSEKEALQEQldERLQELEKMKGMVitetkRQMLETLELKEDEIAQLRSHIKQMTTQGEELrEQKEKSERAAFEE 440
Cdd:PRK04863   403 QQALDVQQTRAIQYQ--QAVQALERAKQLC-----GLPDLTADNAEDWLEEFQAKEQEATEELLSL-EQKLSVAQAAHSQ 474

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  441 LEKALSTAQKT------EDAQR------------RMKMEMDEQMKAvERASEEERLRLQHELSRVRQEAASMAKNSEEQV 502
Cdd:PRK04863   475 FEQAYQLVRKIagevsrSEAWDvarellrrlreqRHLAEQLQQLRM-RLSELEQRLRQQQRAERLLAEFCKRLGKNLDDE 553

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  503 AALQKLHAE---ELASKEQELSrrlEARERelQEQMRIALEKSRSEYLKLTQEKEQQESLALEELElqkkaiLTESENKL 579
Cdd:PRK04863   554 DELEQLQEEleaRLESLSESVS---EARER--RMALRQQLEQLQARIQRLAARAPAWLAAQDALAR------LREQSGEE 622

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  580 QELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKE---LTALAEQHR----TEVEGLQQQQDSLWT 652
Cdd:PRK04863   623 FEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIERLSQPGGSEdprLNALAERFGgvllSEIYDDVSLEDAPYF 702

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  653 ERLqsLSQQHQAAV--------EELREKYQQEKDALLKE------KESLFQAhiQDMNEKTLEKLDKKQMELESVSSE-- 716
Cdd:PRK04863   703 SAL--YGPARHAIVvpdlsdaaEQLAGLEDCPEDLYLIEgdpdsfDDSVFSV--EELEKAVVVKIADRQWRYSRFPEVpl 778

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  717 --------LSEALRA-RDQLAEELSVLRGDADKMKQALE----------------------AELEEQRRHHQREVGSIsE 765
Cdd:PRK04863   779 fgraarekRIEQLRAeREELAERYATLSFDVQKLQRLHQafsrfigshlavafeadpeaelRQLNRRRVELERALADH-E 857

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  766 QQELTVRRAEKALKDELSRLGALLDE----RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQagay 841
Cdd:PRK04863   858 SQEQQQRSQLEQAKEGLSALNRLLPRlnllADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSD---- 933

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  842 EEQLAQMQQKVLDLETEKSLLTKQ------VVEMETH------KKHVCEELDAQ---RAQVQQLERQRSELEEKVR-SLA 905
Cdd:PRK04863   934 PEQFEQLKQDYQQAQQTQRDAKQQafalteVVQRRAHfsyedaAEMLAKNSDLNeklRQRLEQAEQERTRAREQLRqAQA 1013

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  906 QLQD-----SQLKNSTVEKEQARQSLM-EKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKI 979
Cdd:PRK04863  1014 QLAQynqvlASLKSSYDAKRQMLQELKqELQDLGVPADSGAEERARARRDELHARLSANRSRRNQLEKQLTFCEAEMDNL 1093

                          730
                   ....*....|
gi 1907198995  980 KQKAKEMQET 989
Cdd:PRK04863  1094 TKKLRKLERD 1103
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 816-1034 7.03e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 7.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  816 ELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 895
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  896 ELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKR 975
Cdd:COG3883     97 RSGGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198995  976 MEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGIS 1034
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
PRK09039 PRK09039
peptidoglycan -binding protein;
1095-1236 7.18e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.19  E-value: 7.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1095 LRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQE 1174
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907198995 1175 ELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKslEDKSLNLKslLEELASQL 1236
Cdd:PRK09039   124 ELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEK--RDRESQAK--IADLGRRL 181
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 970-1206 8.48e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  970 KNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnaqiLEMAQANSAGISDTVSRLEENQRQQIE 1049
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR-----IRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1050 SLTgAHQRKLDDVIEAWEKKLSQQAAELRdKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAG 1129
Cdd:COG4942     98 ELE-AQKEELAELLRALYRLGRQPPLALL-LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907198995 1130 LQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGcslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQS 1206
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELA-------ELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
mukB PRK04863
chromosome partition protein MukB;
717-1176 9.03e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 9.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  717 LSEALRARDQLAEELSVLRGDADKMKQALEAEL----------EEQRRHHQREVGSIseQQELTvrRAEKALKDELSRLG 786
Cdd:PRK04863   235 MEAALRENRMTLEAIRVTQSDRDLFKHLITESTnyvaadymrhANERRVHLEEALEL--RRELY--TSRRQLAAEQYRLV 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  787 ALLDERDEHLRERQARVQDLEA---HL---------QKSAGELQQALAKLDLLHSEQSAAREQAgayeeqlaqmQQKVLD 854
Cdd:PRK04863   311 EMARELAELNEAESDLEQDYQAasdHLnlvqtalrqQEKIERYQADLEELEERLEEQNEVVEEA----------DEQQEE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  855 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLeRQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIIL 934
Cdd:PRK04863   381 NEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQY-QQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  935 QmreeqakeieiLKQTLSSKEESISILHEEYETKFK-NQEKRMEKIKQKAKEM---QETKKKLLDQEAKLKKELEntvlE 1010
Cdd:PRK04863   460 S-----------LEQKLSVAQAAHSQFEQAYQLVRKiAGEVSRSEAWDVARELlrrLREQRHLAEQLQQLRMRLS----E 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1011 LSQKEKQFNAQILEMAQANSagisdtVSRLEENQRQQIESLTGAHQRKLDDvieawekkLSQQAAELRDKHAEQMEEKEQ 1090
Cdd:PRK04863   525 LEQRLRQQQRAERLLAEFCK------RLGKNLDDEDELEQLQEELEARLES--------LSESVSEARERRMALRQQLEQ 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1091 gLGELRQKVRIVQSEKEELTKEVARLKEAV-----SGQDVaLAGLQGQLEQKSAVIVS---LSERESQLQSQVEKLEADL 1162
Cdd:PRK04863   591 -LQARIQRLAARAPAWLAAQDALARLREQSgeefeDSQDV-TEYMQQLLERERELTVErdeLAARKQALDEEIERLSQPG 668

                          490
                   ....*....|....
gi 1907198995 1163 GCSLSEKLSLQEEL 1176
Cdd:PRK04863   669 GSEDPRLNALAERF 682
COG5022 COG5022
Myosin heavy chain [General function prediction only];
837-1388 9.17e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.68  E-value: 9.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  837 QAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQ----VQQLERQRSELEEKVRSLAQL--QDS 910
Cdd:COG5022    823 QKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQsaqrVELAERQLQELKIDVKSISSLklVNL 902

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  911 QLKNSTVEKEQARQSLMEKENIILQ---------------------MREEQAKEIEIL--KQTLSSKEESISILHEEYET 967
Cdd:COG5022    903 ELESEIIELKKSLSSDLIENLEFKTeliarlkkllnnidleegpsiEYVKLPELNKLHevESKLKETSEEYEDLLKKSTI 982

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  968 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK--KELENTVLELSQKEKQFNAQILEMAQANSagISDTVSRLEENQR 1045
Cdd:COG5022    983 LVREGNKANSELKNFKKELAELSKQYGALQESTKqlKELPVEVAELQSASKIISSESTELSILKP--LQKLKGLLLLENN 1060

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1046 QQIESLTGAHQRKLDDVI-----------EAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVA 1114
Cdd:COG5022   1061 QLQARYKALKLRRENSLLddkqlyqlestENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVN 1140

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1115 RLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEEL-AELKLLADKS------Q 1187
Cdd:COG5022   1141 TLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLkNELIALFSKIfsgwprG 1220

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1188 LRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRC--ERTKALLEAKTNELVCTSRDKADAI 1265
Cdd:COG5022   1221 DKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSsyKLEEEVLPATINSLLQYINVGLFNA 1300

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1266 LArlSQCQRHTATVGEAL----------LRRMGqVSELEAQLTQLTEEQRTLkssfQQVTNQLEEKEKQIKTMK----AD 1331
Cdd:COG5022   1301 LR--TKASSLRWKSATEVnynseelddwCREFE-ISDVDEELEELIQAVKVL----QLLKDDLNKLDELLDACYslnpAE 1373

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198995 1332 IEGLLTEKEALQQEGG--QQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEI 1388
Cdd:COG5022   1374 IQNLKSRYDPADKENNlpKEILKKIEALLIKQELQLSLEGKDETEVHLSEIFSEEKSLI 1432
COG5022 COG5022
Myosin heavy chain [General function prediction only];
338-937 1.09e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.30  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  338 QQRVKRQENLLQRCKETIGShkeqcallLSEKEALQEQLDERLQELEKmkgmvitETKRQMLETLELKEDEIAQLRSHIK 417
Cdd:COG5022    874 AQRVELAERQLQELKIDVKS--------ISSLKLVNLELESEIIELKK-------SLSSDLIENLEFKTELIARLKKLLN 938

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  418 QMTTQGEELREQKEKSERAAFEELEKALSTAQKT-EDAQRRMKMEMDEQMKAVEraseeerlrlqhELSRVRQEAASMAK 496
Cdd:COG5022    939 NIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEyEDLLKKSTILVREGNKANS------------ELKNFKKELAELSK 1006

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  497 NSEeqvaALQKlHAEELASKEQELSrrlearerELQEQMRIaLEKSRSEYLKLTQEKEQQESLALEELELQK--KAILTE 574
Cdd:COG5022   1007 QYG----ALQE-STKQLKELPVEVA--------ELQSASKI-ISSESTELSILKPLQKLKGLLLLENNQLQAryKALKLR 1072

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  575 SENKLQELGQEAEAYRTRILELETsLEKSLQESKTQSEHLA-----VHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDS 649
Cdd:COG5022   1073 RENSLLDDKQLYQLESTENLLKTI-NVKDLEVTNRNLVKPAnvlqfIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSV 1151

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  650 LWTE-----RLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLE----------------KLDKKQM 708
Cdd:COG5022   1152 LQLEldglfWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLKNELIAlfskifsgwprgdklkKLISEGW 1231

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  709 ELESVSSELSEALRARDQLAEE--------LSVLRGDADKMK-QALEAELEEQRRHHQREVGSISEQQELTVRRAEKALK 779
Cdd:COG5022   1232 VPTEYSTSLKGFNNLNKKFDTPasmsneklLSLLNSIDNLLSsYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWK 1311

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  780 --DELSRLGALLDERDehlreRQARVQDLEAHLQksagELQQALAKLDLLHSEQSAAREqagayeeqLAQMQQKVLDLET 857
Cdd:COG5022   1312 saTEVNYNSEELDDWC-----REFEISDVDEELE----ELIQAVKVLQLLKDDLNKLDE--------LLDACYSLNPAEI 1374

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  858 EKSLLTKQVVEMETH-KKHVCEELDAQRAQvqqlERQRSELEEKVRSLAQLQDS--------QLKNSTVEKEQARQSLME 928
Cdd:COG5022   1375 QNLKSRYDPADKENNlPKEILKKIEALLIK----QELQLSLEGKDETEVHLSEIfseeksliSLDRNSIYKEEVLSSLSA 1450

                          650
                   ....*....|..
gi 1907198995  929 ---KENIILQMR 937
Cdd:COG5022   1451 lltKEKIALLDR 1462
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1077-1320 1.10e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1077 LRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKeavsgQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1156
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELA 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1157 KLEADLgcslsEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQsckslhELSKKSLED--KSLNLKSLLEELAS 1234
Cdd:COG3206    237 EAEARL-----AALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELA------ELSARYTPNhpDVIALRAQIAALRA 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1235 QLDSRCERTKALLEAKTNELvctsRDKADAILARLSQcqrhtatvgeaLLRRMGQVSELEAQLTQLTEEQRTLKSSFQQV 1314
Cdd:COG3206    306 QLQQEAQRILASLEAELEAL----QAREASLQAQLAQ-----------LEARLAELPELEAELRRLEREVEVARELYESL 370


                   ....*.
gi 1907198995 1315 TNQLEE 1320
Cdd:COG3206    371 LQRLEE 376
46 PHA02562
endonuclease subunit; Provisional
 849-1088 1.12e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  849 QQKVLDLETEKSLLTKQVvemETHKKHVcEELDAQRAQ-VQQLERQRSELEEKVRSLAQLQDS---QLKNSTVEKEqarq 924
Cdd:PHA02562   180 NQQIQTLDMKIDHIQQQI---KTYNKNI-EEQRKKNGEnIARKQNKYDELVEEAKTIKAEIEEltdELLNLVMDIE---- 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  925 slmEKENIILQMREEQAKeieilkqtLSSKEESISILHEEYET---------KFKNQEKRMEKIKQKAKEMQETKKKLLD 995
Cdd:PHA02562   252 ---DPSAALNKLNTAAAK--------IKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDT 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  996 QEAKLkKELENTVLELSQKEKQFNAQIlemaQANSAGISDTVSRLEENQRqQIESLTGAHQRKLDDVieaweKKLSQQAA 1075
Cdd:PHA02562   321 AIDEL-EEIMDEFNEQSKKLLELKNKI----STNKQSLITLVDKAKKVKA-AIEELQAEFVDNAEEL-----AKLQDELD 389

                          250
                   ....*....|...
gi 1907198995 1076 ELRDKHAEQMEEK 1088
Cdd:PHA02562   390 KIVKTKSELVKEK 402
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 709-954 1.13e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  709 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQeltvrraeKALKDELSRLGAL 788
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQEL--------AALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  789 LDERDEHLRERQARVQDLEAHLQKSAgelQQALAKLdLLHSEQSAAREQAGAYEEQLAQMQQKVLDLetekslLTKQVVE 868
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLG---RQPPLAL-LLSPEDFLDAVRRLQYLKYLAPARREQAEE------LRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  869 METHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQdSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILK 948
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLL-ARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                   ....*.
gi 1907198995  949 QTLSSK 954
Cdd:COG4942    241 ERTPAA 246
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1463-2099 1.14e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1463 EWKKKAQSRLAQHQSTIKDLQAQLDV-----KATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLET 1537
Cdd:TIGR00618  253 EEQLKKQQLLKQLRARIEELRAQEAVleetqERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1538 ALKTQTA--RVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSS 1615
Cdd:TIGR00618  333 HVKQQSSieEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHT-LTQHIHTLQQQKTTLTQKLQSLCKELDILQREQAT 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1616 LEAELGTVKKELEHVNSSvksrDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSEL 1695
Cdd:TIGR00618  412 IDTRTSAFRDLQGQLAHA----KKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETR 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1696 SAQLKEREKQVHSLEDKLKNlESSPHPEVPAVSRSMQSVAASPEQEAPDsqdcTHKACKERLCMLQRRLSEKEKLLRRLE 1775
Cdd:TIGR00618  488 KKAVVLARLLELQEEPCPLC-GSCIHPNPARQDIDNPGPLTRRMQRGEQ----TYAQLETSEEDVYHQLTSERKQRASLK 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1776 QGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVL-IGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQ 1854
Cdd:TIGR00618  563 EQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQdLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELA 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1855 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDgenkcvevLEDRPEENSQSHEIQSNVG 1934
Cdd:TIGR00618  643 LKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYW--------KEMLAQCQTLLRELETHIE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1935 TVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDIlkrECEQEAEEKLKQEQEDLELKHTSTLKQLMR 2014
Cdd:TIGR00618  715 EYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTE---AHFNNNEEVTAALQTGAELSHLAAEIQFFN 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2015 EFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDARE--EEMTGKVTDL 2092
Cdd:TIGR00618  792 RLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKqlAQLTQEQAKI 871


                   ....*..
gi 1907198995 2093 QTQLEEL 2099
Cdd:TIGR00618  872 IQLSDKL 878
PRK01156 PRK01156
chromosome segregation protein; Provisional
 817-1404 1.24e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.12  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  817 LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSE 896
Cdd:PRK01156   178 LRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  897 LEEKVRSLAQLQDSQLKNSTVEKEqarqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILheeyetkfKNQEKRM 976
Cdd:PRK01156   258 IKTAESDLSMELEKNNYYKELEER-----HMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNI--------DAEINKY 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  977 EKIKQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEKQFNAQILEMAQANsagisdtvsRLEENQRQQIESLTGAHQ 1056
Cdd:PRK01156   325 HAIIKKLSVLQKDYNDYIKKKSR-YDDLNNQILELEGYEMDYNSYLKSIESLK---------KKIEEYSKNIERMSAFIS 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1057 RKLdDVIEAWEKKLSQQAAELRDKhaeqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLkeavSGQDVA-LAGLQGQLE 1135
Cdd:PRK01156   395 EIL-KIQEIDPDAIKKELNEINVK----LQDISSKVSSLNQRIRALRENLDELSRNMEML----NGQSVCpVCGTTLGEE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1136 QKSAVIVSLSERESQLQSQVEKLEADLGcSLSEKLSLQEELAElkLLADKSQLRVSELTGQVQAAEKELQSckslHELSK 1215
Cdd:PRK01156   466 KSNHIINHYNEKKSRLEEKIREIEIEVK-DIDEKIVDLKKRKE--YLESEEINKSINEYNKIESARADLED----IKIKI 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1216 KSLEDKSLNLKSLLEELAS----QLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTAtvgEALLRRMGQVS 1291
Cdd:PRK01156   539 NELKDKHDKYEEIKNRYKSlkleDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQ---EIEIGFPDDKS 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1292 ELEAQLTQLTEEQRTLKSSFqqvtNQLEEKEKQIKTMKADIEGL---LTEKEALQQEGGQQRQAASEKESCITQLKKELA 1368
Cdd:PRK01156   616 YIDKSIREIENEANNLNNKY----NEIQENKILIEKLRGKIDNYkkqIAEIDSIIPDLKEITSRINDIEDNLKKSRKALD 691

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1907198995 1369 ENINAVTLLREELSEKKSEIASLSKQLSDLGAQLES 1404
Cdd:PRK01156   692 DAKANRARLESTIEILRTRINELSDRINDINETLES 727
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
332-798 1.27e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  332 KTLEMLQQRVKRQENLLQRCKETIGSHKEqcalLLSEKEALQEQLDERLQELEKMKGMV----ITETKRQMLETLELKED 407
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEELEE----LEEELEELEAELEELREELEKLEKLLqllpLYQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  408 EIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERAsEEERLRLQHELSRV 487
Cdd:COG4717    147 RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAEL-EEELEEAQEELEEL 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  488 RQEAASMAKNSEEQvAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQ 567
Cdd:COG4717    226 EEELEQLENELEAA-ALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  568 KKAILTESENKLQELGQEAEAyrtRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELtaLAEQHRTEVEGLQQQQ 647
Cdd:COG4717    305 EELQALPALEELEEEELEELL---AALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL--QLEELEQEIAALLAEA 379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  648 DSLWTERLQSLSQQHQAAvEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQL 727
Cdd:COG4717    380 GVEDEEELRAALEQAEEY-QELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAEL 458

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198995  728 AEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDElsRLGALLDERDEHLRE 798
Cdd:COG4717    459 EAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE--RLPPVLERASEYFSR 527
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1982-2064 1.33e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.05  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1982 LKRECEQEAEE--KLKQEQEDLELKhtstLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRK 2059
Cdd:PRK00409   528 LERELEQKAEEaeALLKEAEKLKEE----LEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYAS 603


                   ....*
gi 1907198995 2060 IAEKE 2064
Cdd:PRK00409   604 VKAHE 608
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 365-1335 1.40e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.01  E-value: 1.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  365 LLSEKEALQEQLDERLQELEkmkgmvitETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFE-ELEK 443
Cdd:pfam01576   55 LCAEAEEMRARLAARKQELE--------EILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKlQLEK 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  444 ALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLrlqhelsrvrQEAASMAKNSEEQVAALQKL-HAEELASKEQELSR 522
Cdd:pfam01576  127 VTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERI----------SEFTSNLAEEEEKAKSLSKLkNKHEAMISDLEERL 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  523 RLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLAleelelqkKAILTESENKLQELGQEAEAYRTRilelETSLEK 602
Cdd:pfam01576  197 KKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAEL--------RAQLAKKEEELQAALARLEEETAQ----KNNALK 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  603 SLQESKTQSEHLAVHLEAEKNKHNKeltalAEQHRTEvegLQQQQDSLWTERLQSLSQQhqAAVEELREKYQQEKDAL-- 680
Cdd:pfam01576  265 KIRELEAQISELQEDLESERAARNK-----AEKQRRD---LGEELEALKTELEDTLDTT--AAQQELRSKREQEVTELkk 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  681 -LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQAlEAELEEQRRHHQRE 759
Cdd:pfam01576  335 aLEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQA-KQDSEHKRKKLEGQ 413

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  760 V----GSISEQQELTVRRAEKA--LKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSA 833
Cdd:pfam01576  414 LqelqARLSESERQRAELAEKLskLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQ 493

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  834 AREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEM--------------ETHKKHVCEELDAQR-------AQVQQLER 892
Cdd:pfam01576  494 LEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMkkkleedagtlealEEGKKRLQRELEALTqqleekaAAYDKLEK 573

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  893 QRSELEEKVRSLAQLQDSQLKN-STVEKEQAR--QSLMEKENIILQMREE------QAKEIEILKQTLSSKEESISILHE 963
Cdd:pfam01576  574 TKNRLQQELDDLLVDLDHQRQLvSNLEKKQKKfdQMLAEEKAISARYAEErdraeaEAREKETRALSLARALEEALEAKE 653

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  964 EYETKFKNQEKRMEK-------IKQKAKEMQETKKKLLDQEAKLKKELENTVLEL------------------SQKEKQF 1018
Cdd:pfam01576  654 ELERTNKQLRAEMEDlvsskddVGKNVHELERSKRALEQQVEEMKTQLEELEDELqatedaklrlevnmqalkAQFERDL 733

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1019 NA---QILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLD-----DVIEAWEKKLSQQAAELRDKHAeQMEEKEQ 1090
Cdd:pfam01576  734 QArdeQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDlkeleAQIDAANKGREEAVKQLKKLQA-QMKDLQR 812

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1091 GLGELRQ-KVRIVQSEKEE------LTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLG 1163
Cdd:pfam01576  813 ELEEARAsRDEILAQSKESekklknLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIA 892

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1164 cslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSL---HELSKKSLEDKSLNLKSLLEELASQLDSRC 1240
Cdd:pfam01576  893 -------QLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTsqkSESARQQLERQNKELKAKLQEMEGTVKSKF 965

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1241 ERTKALLEAK-----------------TNELVCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1303
Cdd:pfam01576  966 KSSIAALEAKiaqleeqleqesrerqaANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEE 1045

                         1050      1060      1070
                   ....*....|....*....|....*....|..
gi 1907198995 1304 QRTLKSSFQQVTNQLEEKEKQIKTMKADIEGL 1335
Cdd:pfam01576 1046 ASRANAARRKLQRELDDATESNESMNREVSTL 1077
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1936-2133 1.41e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1936 VDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREH------QQELDILKRECE--QEAEEKLKQEQEDLE-LKHT 2006
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEeeyaelQEELEELEEELEelEAELEELREELEKLEkLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2007 STLKQLMREFNTQLAQKEQELER------TVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDA 2080
Cdd:COG4717    128 LPLYQELEALEAELAELPERLEEleerleELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907198995 2081 REEemtgkvtdLQTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLI 2133
Cdd:COG4717    208 LAE--------LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLL 252
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
365-555 1.54e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  365 LLSEKEALQEQLDERLQELEKMK----GMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAA--- 437
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEFRqkngLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALpel 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  438 -----FEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKlhaeE 512
Cdd:COG3206    260 lqspvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQA----Q 335

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1907198995  513 LASKEQELsRRLEARERELQEQMRiALEKSRSEYLKLTQEKEQ 555
Cdd:COG3206    336 LAQLEARL-AELPELEAELRRLER-EVEVARELYESLLQRLEE 376
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 777-1412 1.99e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 1.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  777 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLdllhSEQSAAREQAGAYEEQLAQMQQKVLDLE 856
Cdd:TIGR00618  198 LLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYL----TQKREAQEEQLKKQQLLKQLRARIEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  857 TEKSLLTKQ--VVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLqdsqlknstvekeqarqsLMEKENIIL 934
Cdd:TIGR00618  274 AQEAVLEETqeRINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL------------------LMKRAAHVK 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  935 QMREEQakEIEILKQTLSSKEESISILHEEyETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEntvlelsqK 1014
Cdd:TIGR00618  336 QQSSIE--EQRRLLQTLHSQEIHIRDAHEV-ATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELD--------I 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1015 EKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGE 1094
Cdd:TIGR00618  405 LQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQ 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1095 LRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLqGQLEQKSAVIVSLSERESQLQSQVEKLEADLgcslsekLSLQE 1174
Cdd:TIGR00618  485 ETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDI-DNPGPLTRRMQRGEQTYAQLETSEEDVYHQL-------TSERK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1175 ELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNEL 1254
Cdd:TIGR00618  557 QRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQ 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1255 VCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQrTLKSSFQQVTNQLEEKEKQIKTMKADIEG 1334
Cdd:TIGR00618  637 CSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQ-SEKEQLTYWKEMLAQCQTLLRELETHIEE 715

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198995 1335 LLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKA 1412
Cdd:TIGR00618  716 YDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRL 793
mukB PRK04863
chromosome partition protein MukB;
474-1217 2.06e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 2.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  474 EEERLRLQHELSRVRQEAASmaknSEEQVAALQKLHaEELASKEQELSRRLEARERELQ----------EQMRI--ALEK 541
Cdd:PRK04863   278 ANERRVHLEEALELRRELYT----SRRQLAAEQYRL-VEMARELAELNEAESDLEQDYQaasdhlnlvqTALRQqeKIER 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  542 SRSEYLKLTQEKEQQESLALEELELQkkailTESENKLQELGQEAEAYRTRILELETSLEksLQESKTQSEHLAVHLEAE 621
Cdd:PRK04863   353 YQADLEELEERLEEQNEVVEEADEQQ-----EENEARAEAAEEEVDELKSQLADYQQALD--VQQTRAIQYQQAVQALER 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  622 KNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQ---HQAAVEELREKYQ---------QEKDALLKEKESLFQ 689
Cdd:PRK04863   426 AKQLCGLPDLTADNAEDWLEEFQAKEQEA-TEELLSLEQKlsvAQAAHSQFEQAYQlvrkiagevSRSEAWDVARELLRR 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  690 AHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMkQALEAELEEQRRHHQREVGSISEQQEl 769
Cdd:PRK04863   505 LREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDEL-EQLQEELEARLESLSESVSEARERRM- 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  770 TVRRAEKALKDELSRLGAL------LDERDEHLRE----RQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA- 838
Cdd:PRK04863   583 ALRQQLEQLQARIQRLAARapawlaAQDALARLREqsgeEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIe 662

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  839 ------GAYEEQLAQMQQK---------------------------------VLDLETEKSLLTKQ-------------- 865
Cdd:PRK04863   663 rlsqpgGSEDPRLNALAERfggvllseiyddvsledapyfsalygparhaivVPDLSDAAEQLAGLedcpedlyliegdp 742

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  866 ------VVEMETHKKHVCEEL-DAQ--------------RAQVQQLERQRSELEEKVRSLAQLQ-DSQLKNSTVEK---- 919
Cdd:PRK04863   743 dsfddsVFSVEELEKAVVVKIaDRQwrysrfpevplfgrAAREKRIEQLRAEREELAERYATLSfDVQKLQRLHQAfsrf 822

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  920 -----------------EQARQSLMEKENIILQMRE------EQAKEIEILKQTLSSKEESISILHEEyetkfkNQEKRM 976
Cdd:PRK04863   823 igshlavafeadpeaelRQLNRRRVELERALADHESqeqqqrSQLEQAKEGLSALNRLLPRLNLLADE------TLADRV 896

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  977 EKIKQKAKEMQETkKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgisdtvsrlEENQRQQIESLTGAHQ 1056
Cdd:PRK04863   897 EEIREQLDEAEEA-KRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQT---------QRDAKQQAFALTEVVQ 966

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1057 RKLDDVIEAWEKKLSqQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQ 1136
Cdd:PRK04863   967 RRAHFSYEDAAEMLA-KNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQD 1045

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1137 KSAVIVslSERESQLQSQVEKLEADLGCSLSEKLSLQEELAelklladKSQLRVSELTGQVQAAEKELQSCKSLHELSKK 1216
Cdd:PRK04863  1046 LGVPAD--SGAEERARARRDELHARLSANRSRRNQLEKQLT-------FCEAEMDNLTKKLRKLERDYHEMREQVVNAKA 1116


                   .
gi 1907198995 1217 S 1217
Cdd:PRK04863  1117 G 1117
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 606-850 2.12e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  606 ESKTQSEHLAVHLE---AEKNKHNKELTALAEQHRTEVEGlQQQQDSLWTERLQSLSQQHQAaveeLREKYQQEKDALLK 682
Cdd:NF012221  1539 ESSQQADAVSKHAKqddAAQNALADKERAEADRQRLEQEK-QQQLAAISGSQSQLESTDQNA----LETNGQAQRDAILE 1613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  683 EKESlFQAHIQDMNeKTLEKLDkkqmELESVSSELSEalRARDQLAEE-LSVLRGDADKMKQALEAELEEQRRHH---QR 758
Cdd:NF012221  1614 ESRA-VTKELTTLA-QGLDALD----SQATYAGESGD--QWRNPFAGGlLDRVQEQLDDAKKISGKQLADAKQRHvdnQQ 1685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  759 EVGSISEQQELTVRRAEKalkdelSRLGALLDERDEHlreRQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 838
Cdd:NF012221  1686 KVKDAVAKSEAGVAQGEQ------NQANAEQDIDDAK---ADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                          250
                   ....*....|..
gi 1907198995  839 GAyEEQLAQMQQ 850
Cdd:NF012221  1757 AA-ENKANQAQA 1767
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1921-2112 2.18e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1921 EENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-----EKLK 1995
Cdd:COG4942     38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEllralYRLG 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1996 QEQEDLELKHTSTLKQ------LMREFNTQLAQKEQELERTVQETIDKAQEVEAE------LLESHQEETQQLHRKIAEK 2063
Cdd:COG4942    118 RQPPLALLLSPEDFLDavrrlqYLKYLAPARREQAEELRADLAELAALRAELEAEraeleaLLAELEEERAALEALKAER 197

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1907198995 2064 EDDLRRTARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 2112
Cdd:COG4942    198 QKLLARLEKELAE-LAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 352-1163 2.20e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.50  E-value: 2.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  352 KETIGSHKEQCALLLSEKEALQEQLDERLQ------ELEKMKGMVIT--------ETKRQMLETLELKEDEI-------- 409
Cdd:TIGR00606  151 NNVIFCHQEDSNWPLSEGKALKQKFDEIFSatryikALETLRQVRQTqgqkvqehQMELKYLKQYKEKACEIrdqitske 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  410 AQLRSHIKQMTTQGEELREQKEKSE-----RAAFEELEKALSTAQKTEDAQRRMKMEM-----------DEQMKAVE--- 470
Cdd:TIGR00606  231 AQLESSREIVKSYENELDPLKNRLKeiehnLSKIMKLDNEIKALKSRKKQMEKDNSELelkmekvfqgtDEQLNDLYhnh 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  471 ----RASEEERLRLQHELSRVRQEAASMAKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEY 546
Cdd:TIGR00606  311 qrtvREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSER 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  547 -LKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRT---RILELETSLEKSLQESKTQSEHLAVHLEAEK 622
Cdd:TIGR00606  391 qIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKglgRTIELKKEILEKKQEELKFVIKELQQLEGSS 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  623 NKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLsQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTL-E 701
Cdd:TIGR00606  471 DRILELDQELRKAERELSKAEKNSLTETLKKEVKSL-QNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKdE 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  702 KLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMkqaleaelEEQRRHHQREVGSiSEQQELTVRRAEKALKDE 781
Cdd:TIGR00606  550 QIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQT--------RDRLAKLNKELAS-LEQNKNHINNELESKEEQ 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  782 LSRLGALLDERDEHlRERQARVQDLEAHLQKSAGELQQALAKLDLLHS--EQSAAREQA------------GAYEEQLAQ 847
Cdd:TIGR00606  621 LSSYEDKLFDVCGS-QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQfiTQLTDENQSccpvcqrvfqteAELQEFISD 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  848 MQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQlQDSQLKNSTVEKEQARQSLM 927
Cdd:TIGR00606  700 LQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNR-DIQRLKNDIEEQETLLGTIM 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  928 EKENI---------ILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEK--RMEKIKQKAKEMQetkkKLLDQ 996
Cdd:TIGR00606  779 PEEESakvcltdvtIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqhELDTVVSKIELNR----KLIQD 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  997 EAKLKKELENTVLELsqkeKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESltgAHQRKLDDVIEAWEKKLSQQAAE 1076
Cdd:TIGR00606  855 QQEQIQHLKSKTNEL----KSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREI---KDAKEQDSPLETFLEKDQQEKEE 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1077 LRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARlkeavsgqdvalaGLQGQLEQKSAVIVSLSERESQLQSQVE 1156
Cdd:TIGR00606  928 LISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQD-------------GKDDYLKQKETELNTVNAQLEECEKHQE 994


                   ....*..
gi 1907198995 1157 KLEADLG 1163
Cdd:TIGR00606  995 KINEDMR 1001
PRK11281 PRK11281
mechanosensitive channel MscK;
1951-2154 2.23e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.36  E-value: 2.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1951 ERDKQKLSKEVARLQKELRalrrEHQQELDILKRECEQEAEEKL-KQEQEDLELKHTSTLKQL------MREFNTQLAQK 2023
Cdd:PRK11281    79 KEETEQLKQQLAQAPAKLR----QAQAELEALKDDNDEETRETLsTLSLRQLESRLAQTLDQLqnaqndLAEYNSQLVSL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2024 EQELERtVQETIDKA----QEVEAELLESHQEET-------QQLHRKIA--EKEDDLRRT----ARRYEEILDAREEEMT 2086
Cdd:PRK11281   155 QTQPER-AQAALYANsqrlQQIRNLLKGGKVGGKalrpsqrVLLQAEQAllNAQNDLQRKslegNTQLQDLLQKQRDYLT 233

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198995 2087 GKVTDLQTQLEELQKK-YQQRLEQEESTKDsvtilelQTQLAQKTTLISDSKLKEQELrEQVHNLEDRL 2154
Cdd:PRK11281   234 ARIQRLEHQLQLLQEAiNSKRLTLSEKTVQ-------EAQSQDEAARIQANPLVAQEL-EINLQLSQRL 294
PRK12704 PRK12704
phosphodiesterase; Provisional
 505-685 2.34e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  505 LQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQeslaleelelqkkaiLTESENKLQELGQ 584
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKE---------------LRERRNELQKLEK 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  585 eaeayrtRILELETSLEKSLQESKTQSEhlavHLEAEKNKHNKELTALAEQhRTEVEGLQQQQDslwtERLQSLSQ--QH 662
Cdd:PRK12704    90 -------RLLQKEENLDRKLELLEKREE----ELEKKEKELEQKQQELEKK-EEELEELIEEQL----QELERISGltAE 153

                          170       180
                   ....*....|....*....|....*.
gi 1907198995  663 QA---AVEELREKYQQEKDALLKEKE 685
Cdd:PRK12704   154 EAkeiLLEKVEEEARHEAAVLIKEIE 179
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 417-863 2.46e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 43.12  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  417 KQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKmemdEQMKAVE---RASEEERLRLQHELSRVRQEAAS 493
Cdd:PRK10929    26 KQITQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAK----QYQQVIDnfpKLSAELRQQLNNERDEPRSVPPN 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  494 MAKNSEEQvAALQklhaeeLASKEQELSRRLEarerelQEQMRiALEKSRSeylkLTQEKEQQESLaleelelqkKAILT 573
Cdd:PRK10929   102 MSTDALEQ-EILQ------VSSQLLEKSRQAQ------QEQDR-AREISDS----LSQLPQQQTEA---------RRQLN 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  574 ESENKLQELGQEAeayrtrileleTSLEKSlQESKTQSEHLavhleAEKNKHNK-ELTALAEQHRTEVEGLQQQqdsLWT 652
Cdd:PRK10929   155 EIERRLQTLGTPN-----------TPLAQA-QLTALQAESA-----ALKALVDElELAQLSANNRQELARLRSE---LAK 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  653 ERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQahiqdmNEKTLEKLDKKQMElesVSSELSEALrarDQLAEELS 732
Cdd:PRK10929   215 KRSQQLDAYLQALRNQLNSQRQREAERALESTELLAE------QSGDLPKSIVAQFK---INRELSQAL---NQQAQRMD 282

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  733 VLrgdADKMKQAleaeleeqrrhhqrevgsisEQQELTVRRAEKALKDELSRLGA--LLDERdehLRERQARVQDLEAHL 810
Cdd:PRK10929   283 LI---ASQQRQA--------------------ASQTLQVRQALNTLREQSQWLGVsnALGEA---LRAQVARLPEMPKPQ 336

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907198995  811 QksageLQQALAKL--------DLLHSEQSaAREQAGAYEEQLAQMQQKVLD--LETEKSLLT 863
Cdd:PRK10929   337 Q-----LDTEMAQLrvqrlryeDLLNKQPQ-LRQIRQADGQPLTAEQNRILDaqLRTQRELLN 393
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1858-2171 2.70e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.80  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1858 QEKELTCQALEQRVKELESDLVRERgahrlEVEKLTLKYEKSQSSQQEMDGENKCVEvLEDRPEENSQ--SHEIQSNVGT 1935
Cdd:pfam17380  303 QEKEEKAREVERRRKLEEAEKARQA-----EMDRQAAIYAEQERMAMERERELERIR-QEERKRELERirQEEIAMEISR 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1936 VDGLRSDLESKLTGAERDKQKLskEVARLQKelrALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMRE 2015
Cdd:pfam17380  377 MRELERLQMERQQKNERVRQEL--EAARKVK---ILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERV 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2016 FNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEildaREEEMtgkvtdLQTQ 2095
Cdd:pfam17380  452 RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEE----RKRKL------LEKE 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2096 LEELQK---KYQQRLEQEESTKDSVTILE---LQTQLAQKTTLIS--DSKLKEQELREQVHNLEDRLKRYEKNACAATVG 2167
Cdd:pfam17380  522 MEERQKaiyEEERRREAEEERRKQQEMEErrrIQEQMRKATEERSrlEAMEREREMMRQIVESEKARAEYEATTPITTIK 601


                   ....
gi 1907198995 2168 TPYK 2171
Cdd:pfam17380  602 PIYR 605
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
961-1418 2.91e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  961 LHEEYETKfKNQEKRMEKIKQKAKEMQETKKKLLDQEAklkkELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRL 1040
Cdd:COG4913    240 AHEALEDA-REQIELLEPIRELAERYAAARERLAELEY----LRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1041 EENQRQQIESLTGAHQRKLD---DVIEAWEKKLSQQAAELRDK--HAEQMEEKEQGLG--------ELRQKVRIVQSEKE 1107
Cdd:COG4913    315 EARLDALREELDELEAQIRGnggDRLEQLEREIERLERELEERerRRARLEALLAALGlplpasaeEFAALRAEAAALLE 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1108 ELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLgcslSEKLSLQEelAELKLLADKSQ 1187
Cdd:COG4913    395 ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAL----AEALGLDE--AELPFVGELIE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1188 LRVSELTGQvQAAEKELQSCK------------------SLH----------ELSKKSLEDKSLNLKSLLEELASQLDSR 1239
Cdd:COG4913    469 VRPEEERWR-GAIERVLGGFAltllvppehyaaalrwvnRLHlrgrlvyervRTGLPDPERPRLDPDSLAGKLDFKPHPF 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1240 CERTKALLEAKTNELVCTS----RDKADAILArlsQCQ-RHTATVGEALLRRMG------------QVSELEAQLTQLTE 1302
Cdd:COG4913    548 RAWLEAELGRRFDYVCVDSpeelRRHPRAITR---AGQvKGNGTRHEKDDRRRIrsryvlgfdnraKLAALEAELAELEE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1303 EQRTLKSSFQQVTNQLEEKEKQIKTMKA---------DIEGLLTEKEALQqeggQQRQAASEKESCITQLKKELAENINA 1373
Cdd:COG4913    625 ELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAELE----AELERLDASSDDLAALEEQLEELEAE 700

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 1907198995 1374 VTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISAL 1418
Cdd:COG4913    701 LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745
Gp58 pfam07902
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
 598-852 3.12e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 42.63  E-value: 3.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  598 TSLEKSLQESKTQSEHLAVHLEAEKNK-----------------HNKELTA----LAEQHRTEVEGLQQQQDSLWTERLQ 656
Cdd:pfam07902   74 TGLFKSLEEMLSQLKELNLELTDTKNSnlwskiklnnngmlreyHNDTIKTeiveSAEGIATRISEDTDKKLALINETIS 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  657 SLSQQHQAAVEELREKYQQEKDAL---LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEAlrARDQLAEELSV 733
Cdd:pfam07902  154 GIRREYQDADRQLSSSYQAGIEGLkatMASDKIGLQAEIQASAQGLSQRYDNEIRKLSAKITTTSSG--TTEAYESKLDD 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  734 LRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKAlkdeLSRLGALLDerdehlrERQARVQDLEahlqKS 813
Cdd:pfam07902  232 LRAEFTRSNQGMRTELESKISGLQSTQQSTAYQISQEISNREGA----VSRVQQDLD-------SYQRRLQDAE----KN 296

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1907198995  814 AGELQQALAKLdllhseQSAAREQAGAYEEQLAQMQ----QKV 852
Cdd:pfam07902  297 YSSLTQTVKGL------QSTVSDPNSKLESRITQLAglieQKV 333
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 190-759 3.19e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.65  E-value: 3.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  190 REQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQ--------SQDKSLRRISE----LREELQMDQQAK 257
Cdd:TIGR00618  309 AQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQeihirdahEVATSIREISCqqhtLTQHIHTLQQQK 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  258 KHLQDEFDACLEEKDQYISVLQTQVSLLKQRlqngpmnvdapkplPPGELQAEVHGDTEKMEGVGEPVGGGTSAKTLEML 337
Cdd:TIGR00618  389 TTLTQKLQSLCKELDILQREQATIDTRTSAF--------------RDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCE 454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  338 QQRVKRQENLLQRCKETIG--SHKEQCALLLSEKEALQEQLDERLQELEKM--KGMVITETKRQMLETLELKEDEIAQLR 413
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQqlQTKEQIHLQETRKKAVVLARLLELQEEPCPlcGSCIHPNPARQDIDNPGPLTRRMQRGE 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  414 SHIKQMTTQGEELREQKEkSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEeerlRLQHELSrvrqeaas 493
Cdd:TIGR00618  535 QTYAQLETSEEDVYHQLT-SERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV----RLQDLTE-------- 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  494 maKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILT 573
Cdd:TIGR00618  602 --KLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQ 679

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  574 ESENKLQELGQEAEAYR---TRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAE-------------QHR 637
Cdd:TIGR00618  680 LALQKMQSEKEQLTYWKemlAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQslkelmhqartvlKAR 759

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  638 TEVEGLQQQQDSLWTERLQSLsqQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSEL 717
Cdd:TIGR00618  760 TEAHFNNNEEVTAALQTGAEL--SHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRL 837

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1907198995  718 SEalraRDQLAEELSVLRGDADKMKQALEAELEEQRRHHQRE 759
Cdd:TIGR00618  838 EE----KSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 844-1024 3.36e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 3.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  844 QLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNSTVEKEQA 922
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVeARIKKYEEQLGNVRNNKE 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  923 RQSLMekeniilqmreeqaKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 1002
Cdd:COG1579     91 YEALQ--------------KEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA 156

                          170       180
                   ....*....|....*....|..
gi 1907198995 1003 ELENTVLELSQKEKQFNAQILE 1024
Cdd:COG1579    157 ELEELEAEREELAAKIPPELLA 178
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1574-1717 3.39e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.54  E-value: 3.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1574 RDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELgtvkkelehvnssvKSRDGELKALEDKLElesa 1653
Cdd:COG2433    390 LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEL--------------EEKDERIERLERELS---- 451

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198995 1654 akvELKRKAEQKIaairkqllsqmeeKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1717
Cdd:COG2433    452 ---EARSEERREI-------------RKDREISRLDREIERLERELEEERERIEELKRKLERLK 499
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1103-1327 3.44e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1103 QSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLL 1182
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1183 AdKSQLRVSELTGQvQAAEKELQSCKSLHELSKKSLEDKSLN--LKSLLEELASQLDsRCERTKALLEAKTNELvctsRD 1260
Cdd:COG4942    106 L-AELLRALYRLGR-QPPLALLLSPEDFLDAVRRLQYLKYLApaRREQAEELRADLA-ELAALRAELEAERAEL----EA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907198995 1261 KADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKT 1327
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 329-527 3.47e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  329 TSAKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLeLKEDE 408
Cdd:COG4942     52 ALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALL-LSPED 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  409 IAQLRSHIKQMTTQGEELREQKE--KSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSR 486
Cdd:COG4942    131 FLDAVRRLQYLKYLAPARREQAEelRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAE 210

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1907198995  487 VRQEAASMAKNSEEQVAALQKLHAEELASKEQELSRRLEAR 527
Cdd:COG4942    211 LAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1083-1702 3.64e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 3.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1083 EQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEA-- 1160
Cdd:PRK03918   158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEElk 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1161 -DLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE-----DKSLNLKSLLEELAS 1234
Cdd:PRK03918   238 eEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKlsefyEEYLDELREIEKRLS 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1235 QLDSRCERTKALLE--AKTNELVCTSRDKADAILARLSQCQRHTATVGEAlLRRMGQVSELEAQLTQLTEEqrtlkssfq 1312
Cdd:PRK03918   318 RLEEEINGIEERIKelEEKEERLEELKKKLKELEKRLEELEERHELYEEA-KAKKEELERLKKRLTGLTPE--------- 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1313 QVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKES-------CITQLKKELAENINAVtlLREELSEKK 1385
Cdd:PRK03918   388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvCGRELTEEHRKELLEE--YTAELKRIE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1386 SEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEkmsaLEQVDHWSNKFsewk 1465
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEE----YEKLKEKLIKL---- 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1466 KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQIC-LLKEDLDRQNKKFECLKGEMEvRKSKMEKKECDLETALKTQTA 1544
Cdd:PRK03918   538 KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAeLLKELEELGFESVEELEERLK-ELEPFYNEYLELKDAEKELER 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1545 RVVELEDCVTQRKKEVESLNETLKNYNQQRdtehsglvqrlQHLEELGEE-KDNKVREAEETVLRLREHVSSLEAELGTV 1623
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELAETEKRLEELR-----------KELEELEKKySEEEYEELREEYLELSRELAGLRAELEEL 685

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198995 1624 KKELEHVNSSVKSRDGELKALEDKLElesaaKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKER 1702
Cdd:PRK03918   686 EKRREEIKKTLEKLKEELEEREKAKK-----ELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEELTEG 759
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1955-2147 3.85e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 3.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1955 QKLSKEVARLQKELRALRREH------QQELDILKRECEQEAE-EKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQEL 2027
Cdd:COG3206    185 PELRKELEEAEAALEEFRQKNglvdlsEEAKLLLQQLSELESQlAEARAELAEAEARLAALRAQLGSGPDALPELLQSPV 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2028 ERTVQETIDKAQEVEAELLESHQEET---QQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQ 2104
Cdd:COG3206    265 IQQLRAQLAELEAELAELSARYTPNHpdvIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLA 344

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1907198995 2105 QRLEQEestkdsVTILELQTQLAQKTTLISD--SKLKEQELREQV 2147
Cdd:COG3206    345 ELPELE------AELRRLEREVEVARELYESllQRLEEARLAEAL 383
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 974-1589 4.16e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 42.43  E-value: 4.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  974 KRMEKIKQKAKEMQETKKKLLDQEAKLKKE-LENTVLELSQKEKQFNAQILEMAQAnsaGISDTVSRLEENQRQQIESLT 1052
Cdd:pfam07111   70 RQLQELRRLEEEVRLLRETSLQQKMRLEAQaMELDALAVAEKAGQAEAEGLRAALA---GAEMVRKNLEEGSQRELEEIQ 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1053 GAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQkVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQG 1132
Cdd:pfam07111  147 RLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQ-LAEAQKEAELLRKQLSKTQEELEAQVTLVESLRK 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1133 QLEQKSAVIVSLSERESQLQSQVEKLEadlgcslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSckslhe 1212
Cdd:pfam07111  226 YVGEQVPPEVHSQTWELERQELLDTMQ-----------HLQEDRADLQATVELLQVRVQSLTHMLALQEEELTR------ 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1213 lskksledKSLNLKSLLEELASqldsrcertkalleaKTNELVCTSRDKADAILARL-SQCQRHTATVGEAllrrMGQVS 1291
Cdd:pfam07111  289 --------KIQPSDSLEPEFPK---------------KCRSLLNRWREKVFALMVQLkAQDLEHRDSVKQL----RGQVA 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1292 ELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQ-------AASEKESCITQLK 1364
Cdd:pfam07111  342 ELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEEqlkfvvnAMSSTQIWLETTM 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1365 KELAENINAVTLLREELSEKKSEIAS----LSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKV 1440
Cdd:pfam07111  422 TRVEQAVARIPSLSNRLSYAVRKVHTikglMARKVALAQLRQESCPPPPPAPPVDADLSLELEQLREERNRLDAELQLSA 501

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1441 DALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKF----EC 1516
Cdd:pfam07111  502 HLIQQEVGRAREQGEAERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYgqalQE 581

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198995 1517 LKGEMEVR-KSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLE 1589
Cdd:pfam07111  582 KVAEVETRlREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERNQELRRLQDEARKEEGQRLARRVQELE 655
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1488-2157 4.21e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 4.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1488 VKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEK---KECDLETALKTQTARVVELEDCVTQRKKEVESLN 1564
Cdd:PRK03918   141 LESDESREKVVRQILGLDDYENAYKNLGEVIKEIKRRIERLEKfikRTENIEELIKEKEKELEEVLREINEISSELPELR 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1565 ETLKNYnqqrdtehSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKAL 1644
Cdd:PRK03918   221 EELEKL--------EKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK----ELKEL 288

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1645 EDKlELESAAKVELKRKAEQKIAAIRKQL--LSQMEEKTQRYAKDTEN---RLSELSAQLKEREKQVHSLEDKLKNLEss 1719
Cdd:PRK03918   289 KEK-AEEYIKLSEFYEEYLDELREIEKRLsrLEEEINGIEERIKELEEkeeRLEELKKKLKELEKRLEELEERHELYE-- 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1720 phpEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARpsqpEAQHRALSGKLDC 1799
Cdd:PRK03918   366 ---EAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELK----KAIEELKKAKGKC 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1800 -TRARQLEDHVLIGCLPEELEEkmkcslivsqpmgeetgnntgvkqnwasvVDSVQKTLQEKELTCQALEQRVKELESDL 1878
Cdd:PRK03918   439 pVCGRELTEEHRKELLEEYTAE-----------------------------LKRIEKELKEIEEKERKLRKELRELEKVL 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1879 VRERgahrlEVEKLTLKYEKSQSSQQEMDGENkcvevLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLtgaeRDKQKLS 1958
Cdd:PRK03918   490 KKES-----ELIKLKELAEQLKELEEKLKKYN-----LEELEKKAEEYEKLKEKLIKLKGEIKSLKKEL----EKLEELK 555

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1959 KEVARLQKELRALRREHQQELDILKR---ECEQEAEEKLKQeqedlelkhtstLKQLMREFNTqLAQKEQELERtvqeti 2035
Cdd:PRK03918   556 KKLAELEKKLDELEEELAELLKELEElgfESVEELEERLKE------------LEPFYNEYLE-LKDAEKELER------ 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2036 dkaqevEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKD 2115
Cdd:PRK03918   617 ------EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRRE 690

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907198995 2116 SV--TILELQTQLAQKTTLISDSKLKE------QELREQVHNLEDRLKRY 2157
Cdd:PRK03918   691 EIkkTLEKLKEELEEREKAKKELEKLEkalervEELREKVKKYKALLKER 740
PLN02939 PLN02939
transferase, transferring glycosyl groups
 908-1231 4.25e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.58  E-value: 4.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  908 QDSQLKN----STVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILH-EEYETKFKNQEKRMEKIKQK 982
Cdd:PLN02939    71 ENGQLENtslrTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQlEDLVGMIQNAEKNILLLNQA 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  983 AKEMQETKKKLLDQEAKLKKELENTVLELSQK--------EKQFNAQIL---------EMAQANSAGISDTVSRLEENQR 1045
Cdd:PLN02939   151 RLQALEDLEKILTEKEALQGKINILEMRLSETdariklaaQEKIHVEILeeqleklrnELLIRGATEGLCVHSLSKELDV 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1046 QQIESLTgahqrkLDDVIEAWEKKLS--QQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEEL-TKEVARLKEAVSG 1122
Cdd:PLN02939   231 LKEENML------LKDDIQFLKAELIevAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLsPLQYDCWWEKVEN 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1123 QDVALAGLQGQLEQKSAVIvslsERESQLQSQVEKLEADLGCSLSEKLSLQeelaelklLADKSQLRVSELTGQVQAAEK 1202
Cdd:PLN02939   305 LQDLLDRATNQVEKAALVL----DQNQDLRDKVDKLEASLKEANVSKFSSY--------KVELLQQKLKLLEERLQASDH 372

                          330       340
                   ....*....|....*....|....*....
gi 1907198995 1203 ELQSCKSLHELSKKSLEDkslNLKSLLEE 1231
Cdd:PLN02939   373 EIHSYIQLYQESIKEFQD---TLSKLKEE 398
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
702-827 4.86e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.57  E-value: 4.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  702 KLDKKQMELESVSSELsEALRARDQLAEELSVLRGDADKMKQALE-AELEEQRRHHQREVGSISEQQELTVRRAEKALKD 780
Cdd:COG1566     84 ALAQAEAQLAAAEAQL-ARLEAELGAEAEIAAAEAQLAAAQAQLDlAQRELERYQALYKKGAVSQQELDEARAALDAAQA 162

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198995  781 ELSRLGALLDERDEHLRErQARVQDLEAHLQKSAGELQQALAKLDLL 827
Cdd:COG1566    163 QLEAAQAQLAQAQAGLRE-EEELAAAQAQVAQAEAALAQAELNLART 208
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 374-482 5.10e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.99  E-value: 5.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  374 EQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGE-------ELREQKEKSERAAFE--ELEKA 444
Cdd:COG0542    414 DELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEaekelieEIQELKEELEQRYGKipELEKE 493

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1907198995  445 LSTAQKTEDAQRRM-KMEMDEQMKA----------VERASEEERLRLQH 482
Cdd:COG0542    494 LAELEEELAELAPLlREEVTEEDIAevvsrwtgipVGKLLEGEREKLLN 542
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 332-927 5.52e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 42.09  E-value: 5.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  332 KTLEMLQQRVKRQENLLQRCKETigsHKEQCALLLSEKEALQEQLDERLQeLEKMKGMVITETKRQMLETLELKEDEIAQ 411
Cdd:PRK10246   233 KQLLTAQQQQQQSLNWLTRLDEL---QQEASRRQQALQQALAAEEKAQPQ-LAALSLAQPARQLRPHWERIQEQSAALAH 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  412 LRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQK------TEDAQRRMKMEMdeqmkAVERASEEERLRLQHELS 485
Cdd:PRK10246   309 TRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSlntwlaEHDRFRQWNNEL-----AGWRAQFSQQTSDREQLR 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  486 RVRQEAASMAKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELE 565
Cdd:PRK10246   384 QWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAAL 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  566 LQKKAILTESENKLQELGQEAEAyRTRILELEtSLEKSLQESKT-----QSEHLAVH----LEAEKNKH-----NKELTA 631
Cdd:PRK10246   464 NEMRQRYKEKTQQLADVKTICEQ-EARIKDLE-AQRAQLQAGQPcplcgSTSHPAVEayqaLEPGVNQSrldalEKEVKK 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  632 LAEQH---RTEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQM 708
Cdd:PRK10246   542 LGEEGaalRGQLDALTKQLQRD-ESEAQSLRQEEQALTQQWQAVCASLNITLQPQDDIQPWLDAQEEHERQLRLLSQRHE 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  709 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTvrrAEKALKDELSRLGAL 788
Cdd:PRK10246   621 LQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEASWLATRQQEAQSWQQRQN---ELTALQNRIQQLTPL 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  789 LD---ERDEHLRER------------------QARVQDLEAHLQKSAGELQQALAKLD--LLHS--EQSAAREQAGAYEE 843
Cdd:PRK10246   698 LEtlpQSDDLPHSEetvaldnwrqvheqclslHSQLQTLQQQDVLEAQRLQKAQAQFDtaLQASvfDDQQAFLAALLDEE 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  844 QLAQMQQKVLDLETE----KSLLTKQVVEMETHKKHVCEELDAQrAQVQQLERQRSELEEKVRSLAQLQD---SQLKNST 916
Cdd:PRK10246   778 TLTQLEQLKQNLENQrqqaQTLVTQTAQALAQHQQHRPDGLDLT-VTVEQIQQELAQLAQQLRENTTRQGeirQQLKQDA 856

                          650
                   ....*....|.
gi 1907198995  917 vEKEQARQSLM 927
Cdd:PRK10246   857 -DNRQQQQALM 866
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1618-1974 5.85e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 5.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1618 AELGTVKKELEHVNSSVKSRDGELKALEDKLE--LESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSEL 1695
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREkaERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1696 SAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDcTHKACKERLCMLQRRLSEKEKLLRRLE 1775
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLER-SIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1776 qgegearpsqpeAQHRALSGKLDCTRARQLEdhvligcLPEELEEKmkcslivsqpmgeetgnntgvkqnwASVVDSVQK 1855
Cdd:TIGR02169  336 ------------AEIEELEREIEEERKRRDK-------LTEEYAEL-------------------------KEELEDLRA 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1856 TLQEKELTCQALEQRVKELE---SDLVRERGAHRLEVEKLtlKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSN 1932
Cdd:TIGR02169  372 ELEEVDKEFAETRDELKDYReklEKLKREINELKRELDRL--QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE 449

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1907198995 1933 VGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRRE 1974
Cdd:TIGR02169  450 IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 929-1151 5.86e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 5.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  929 KENIIlqmreEQAKEIeilkqtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTV 1008
Cdd:PRK00409   500 PENII-----EEAKKL------IGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLL 568

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1009 LELSQKEKqfnaQILEMAQANSAGIsdtVSRLEENQRQQIESLtgahqrKLDDVIEAweKKLSQQAAELRDKHAEQMEEK 1088
Cdd:PRK00409   569 EEAEKEAQ----QAIKEAKKEADEI---IKELRQLQKGGYASV------KAHELIEA--RKRLNKANEKKEKKKKKQKEK 633

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907198995 1089 EQGL--GE------LRQKVRIVQ-SEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQL 1151
Cdd:PRK00409   634 QEELkvGDevkylsLGQKGEVLSiPDDKEAIVQAGIMKMKVPLSDLEKIQKPKKKKKKKPKTVKPKPRTVSL 705
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
400-601 6.04e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 6.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  400 ETLELKEDEIAQLRSHIKQmttQGEELREQKEKSERA--AFEELEKALSTAQKTEDAQRRMKmEMDEQMKAV--ERASEE 475
Cdd:COG3206    164 QNLELRREEARKALEFLEE---QLPELRKELEEAEAAleEFRQKNGLVDLSEEAKLLLQQLS-ELESQLAEAraELAEAE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  476 ERLR-LQHELSRVRQEAASMAKNSE-----EQVAALQKLHAEELAS------KEQELSRRLEARERELQEQMRIALEKSR 543
Cdd:COG3206    240 ARLAaLRAQLGSGPDALPELLQSPViqqlrAQLAELEAELAELSARytpnhpDVIALRAQIAALRAQLQQEAQRILASLE 319

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198995  544 SEYLKLTQEKEQQESLALEELELQKKaiLTESENKLQELGQEAEAYRTRILELETSLE 601
Cdd:COG3206    320 AELEALQAREASLQAQLAQLEARLAE--LPELEAELRRLEREVEVARELYESLLQRLE 375
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1937-2047 6.05e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 6.05e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  1937 DGLRSDLESKLTGAERDKQKLSKE-------VARLQKELRALRREHQQeLDILKRECEQEAEEKLKQEQEDLElkhtSTL 2009
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKElellnsiKPKLRDRKDALEEELRQ-LKQLEDELEDCDPTELDRAKEKLK----KLL 217

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 1907198995  2010 KQLMREFN--TQLAQKEQELERTVQETIDKAQEVEAELLE 2047
Cdd:smart00787  218 QEIMIKVKklEELEEELQELESKIEDLTNKKSELNTEIAE 257
PRK01156 PRK01156
chromosome segregation protein; Provisional
 576-1118 6.48e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.81  E-value: 6.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  576 ENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSE----------------HLAVHLEAEKNKHNKELTALaeQHRTE 639
Cdd:PRK01156   189 EEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIeynnamddynnlksalNELSSLEDMKNRYESEIKTA--ESDLS 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  640 VEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAhiqDMNEKTLEKLDKKQMELESVSSELSE 719
Cdd:PRK01156   267 MELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNI---DAEINKYHAIIKKLSVLQKDYNDYIK 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  720 ALRARDQLAEELSVLRGDADKMKQALEA--ELEEQRRHHQREVGSISEQQELTVRRAE---KALKDELSRLGALLDERDE 794
Cdd:PRK01156   344 KKSRYDDLNNQILELEGYEMDYNSYLKSieSLKKKIEEYSKNIERMSAFISEILKIQEidpDAIKKELNEINVKLQDISS 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  795 HLRERQARVQDLEAHLQksagELQQALAKLD--------LLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQV 866
Cdd:PRK01156   424 KVSSLNQRIRALRENLD----ELSRNMEMLNgqsvcpvcGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKI 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  867 VEMETHKKHVC-EELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKnstvekeqarqslmeKENIILQMReeqAKEIE 945
Cdd:PRK01156   500 VDLKKRKEYLEsEEINKSINEYNKIESARADLEDIKIKINELKDKHDK---------------YEEIKNRYK---SLKLE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  946 ILKQTLSSKEESISILHE-EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNaqile 1024
Cdd:PRK01156   562 DLDSKRTSWLNALAVISLiDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYN----- 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1025 MAQANSAGIsDTVSRLEENQRQQIESLtgahqrkldDVIEAWEKKLSQQAAELRD---KHAEQMEEKEQGLGELRQKVRI 1101
Cdd:PRK01156   637 EIQENKILI-EKLRGKIDNYKKQIAEI---------DSIIPDLKEITSRINDIEDnlkKSRKALDDAKANRARLESTIEI 706

                          570
                   ....*....|....*..
gi 1907198995 1102 VQSEKEELTKEVARLKE 1118
Cdd:PRK01156   707 LRTRINELSDRINDINE 723
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 890-1118 8.24e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 8.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  890 LERQRSELEEKVRSL--AQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYET 967
Cdd:PRK05771    14 LKSYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEE 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  968 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKeLENTVLELsqkekqfnaqILEMAQANSAGISDTVSRLEENQRQQ 1047
Cdd:PRK05771    94 ELEKIEKEIKELEEEISELENEIKELEQEIERLEP-WGNFDLDL----------SLLLGFKYVSVFVGTVPEDKLEELKL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1048 IESLTGA---HQRKLDDVIEAW-EKKLSQQAAELRDKH-AEQMEEKEQG-----LGELRQKVRIVQSEKEELTKEVARLK 1117
Cdd:PRK05771   163 ESDVENVeyiSTDKGYVYVVVVvLKELSDEVEEELKKLgFERLELEEEGtpselIREIKEELEEIEKERESLLEELKELA 242


                   .
gi 1907198995 1118 E 1118
Cdd:PRK05771   243 K 243
PRK11281 PRK11281
mechanosensitive channel MscK;
989-1407 8.33e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.44  E-value: 8.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  989 TKKKLLDQEAKL-KKELENTVLELSQKEKQfnaqilemaqansagisdtvsrleenqRQQIESLtgahqrklddvieawE 1067
Cdd:PRK11281    49 NKQKLLEAEDKLvQQDLEQTLALLDKIDRQ---------------------------KEETEQL---------------K 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1068 KKLSQQAAELRDKHAEQMEEKEQGLGELRQK-----VRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIV 1142
Cdd:PRK11281    87 QQLAQAPAKLRQAQAELEALKDDNDEETRETlstlsLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALY 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1143 SLSERESQLQSQVEKLEAD-LGCSLSEKLSLQEELAEL--------KLLADKSQL------RVSELTGQVQAAEKELQ-- 1205
Cdd:PRK11281   167 ANSQRLQQIRNLLKGGKVGgKALRPSQRVLLQAEQALLnaqndlqrKSLEGNTQLqdllqkQRDYLTARIQRLEHQLQll 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1206 ----SCKSLHELSKKSLEDKSLNLKSLLEE---LASQLDSRCERTKALLEA--KTNELvctSRD--KADAILARLSQCQR 1274
Cdd:PRK11281   247 qeaiNSKRLTLSEKTVQEAQSQDEAARIQAnplVAQELEINLQLSQRLLKAteKLNTL---TQQnlRVKNWLDRLTQSER 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1275 HtatvgeallrrmgqvseLEAQLTQLteeQRTLKSS---FQQvtNQLEEKEKQIKTMKADIEGLLTEkealQQEGGQQRQ 1351
Cdd:PRK11281   324 N-----------------IKEQISVL---KGSLLLSrilYQQ--QQALPSADLIEGLADRIADLRLE----QFEINQQRD 377

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198995 1352 AASEKESCITQLKKELAENINAVTL--LREELSEKKSEIASLSKQlsdLGAQLESSIS 1407
Cdd:PRK11281   378 ALFQPDAYIDKLEAGHKSEVTDEVRdaLLQLLDERRELLDQLNKQ---LNNQLNLAIN 432
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1289-1404 9.00e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 9.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995 1289 QVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKAD--IEGLLTEKEALQQEGGQQRQAASEKESCITQLKKE 1366
Cdd:COG3206    220 QLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQ 299

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1907198995 1367 LAENINAV-TLLREELSEKKSEIASLSKQLSDLGAQLES 1404
Cdd:COG3206    300 IAALRAQLqQEAQRILASLEAELEALQAREASLQAQLAQ 338
PRK12704 PRK12704
phosphodiesterase; Provisional
 363-517 9.17e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.92  E-value: 9.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  363 ALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMttqgEELREQKEKSERAAFEELE 442
Cdd:PRK12704    31 AKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKL----EKRLLQKEENLDRKLELLE 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198995  443 KALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQH--ELSR--------------VRQEAASMAKNSEEQvaalq 506
Cdd:PRK12704   107 KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERisGLTAeeakeillekveeeARHEAAVLIKEIEEE----- 181

                          170
                   ....*....|.
gi 1907198995  507 klhAEELASKE 517
Cdd:PRK12704   182 ---AKEEADKK 189
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH