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Conserved domains on  [gi|1907198992|ref|XP_036011003|]
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golgin subfamily A member 4 isoform X13 [Mus musculus]

Protein Classification

Gp58 and Grip domain-containing protein( domain architecture ID 13382842)

Gp58 and Grip domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 406-987 4.01e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.63  E-value: 4.01e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  406 EDEIAQLRSHIKQMTTQGE------ELREQKEKSE-RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 477
Cdd:COG1196    192 EDILGELERQLEPLERQAEkaeryrELKEELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  478 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 557
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  558 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 637
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  638 RTEVEGLQQQQDSL-----WTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHiqdmNEKTLEKLDKKQMELE 712
Cdd:COG1196    431 AELEEEEEEEEEALeeaaeEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA----ARLLLLLEAEADYEGF 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  713 SVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALL 790
Cdd:COG1196    507 LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARA 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  791 DERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEM 870
Cdd:COG1196    587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SL 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  871 ETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQ 950
Cdd:COG1196    663 TGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1907198992  951 TLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 987
Cdd:COG1196    743 EEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 698-1304 1.85e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.85e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  698 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 775
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  776 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 855
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  856 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 935
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  936 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 1014
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1015 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1090
Cdd:COG1196    487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1091 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1170
Cdd:COG1196    567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1171 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1250
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198992 1251 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1304
Cdd:COG1196    720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1024-1718 1.80e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 1.80e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1024 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1098
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1099 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1178
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1179 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1258
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1259 SRDKAD----AILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1334
Cdd:TIGR02168  420 QQEIEEllkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1335 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1404
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1405 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1460
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1461 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1524
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1525 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1591
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1592 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1671
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198992 1672 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1718
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1494-2162 1.92e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.92e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1494 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1573
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1574 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1653
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1654 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1733
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1734 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1810
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1811 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1863
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1864 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1926
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1927 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 2006
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2007 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2086
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2087 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2161
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907198992 2162 A 2162
Cdd:TIGR02168  910 R 910
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2187-2230 3.62e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.45  E-value: 3.62e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907198992  2187 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2230
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
241-519 6.11e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 6.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  241 RRISELREELQMDQQAKKHLQDEFDACLEEKDQyisvLQTQVSLLKQRLQNGPMNVDAPkplppgELQAEVHgdtekmEG 320
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDA----LQERREALQRLAEYSWDEIDVA------SAEREIA------EL 673

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  321 VGEPVGGGTSAKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETkRQMLE 400
Cdd:COG4913    674 EAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL-RALLE 752

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  401 TLELKEDEIAQLRSHIKQMTTQGEELREQKEKSEraafEELEKALStaqkteDAQRRMKMEMDEQMKAVERASE-EERLR 479
Cdd:COG4913    753 ERFAAALGDAVERELRENLEERIDALRARLNRAE----EELERAMR------AFNREWPAETADLDADLESLPEyLALLD 822

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1907198992  480 --LQHELSRVRQEAASMAKKNSEEQVAALQ-KLHAEELASKEQ 519
Cdd:COG4913    823 rlEEDGLPEYEERFKELLNENSIEFVADLLsKLRRAIREIKER 865
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 406-987 4.01e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.63  E-value: 4.01e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  406 EDEIAQLRSHIKQMTTQGE------ELREQKEKSE-RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 477
Cdd:COG1196    192 EDILGELERQLEPLERQAEkaeryrELKEELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  478 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 557
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  558 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 637
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  638 RTEVEGLQQQQDSL-----WTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHiqdmNEKTLEKLDKKQMELE 712
Cdd:COG1196    431 AELEEEEEEEEEALeeaaeEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA----ARLLLLLEAEADYEGF 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  713 SVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALL 790
Cdd:COG1196    507 LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARA 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  791 DERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEM 870
Cdd:COG1196    587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SL 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  871 ETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQ 950
Cdd:COG1196    663 TGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1907198992  951 TLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 987
Cdd:COG1196    743 EEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 698-1304 1.85e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.85e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  698 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 775
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  776 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 855
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  856 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 935
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  936 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 1014
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1015 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1090
Cdd:COG1196    487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1091 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1170
Cdd:COG1196    567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1171 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1250
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198992 1251 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1304
Cdd:COG1196    720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 698-1404 3.01e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.52  E-value: 3.01e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  698 EKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRGDADKMkQALEAELEEQRRHHQREVGSISEQQELTVRRAEK 777
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  778 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 856
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  857 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ----RSELEEKVRSLAQLQDsQLKNSTVEKEQA---RQSLME 929
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEledlRAELEEVDKEFAETRD-ELKDYREKLEKLkreINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  930 KENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA---KLKKELE 1006
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1007 NTVLELSQKEKQ---------FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 1077
Cdd:TIGR02169  487 KLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1078 LRDKHA--------EQMEEKEQGLGELRQK------VRIVQSEKEELTKEVARLKEAVSGQDVALA----------GLQG 1133
Cdd:TIGR02169  567 LKRRKAgratflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAArrlmgkyrmvTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1134 QLEQKSAVIVSLSERESQLQS-------QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1206
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1207 SCKSLHELSK----------KSLEDKSLNLKSLLEELASQLDSRcERTKALLEAKTNELvctsrdKADAILARLSQCQRH 1276
Cdd:TIGR02169  727 QLEQEEEKLKerleeleedlSSLEQEIENVKSELKELEARIEEL-EEDLHKLEEALNDL------EARLSHSRIPEIQAE 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1277 TATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASE 1356
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198992 1357 KESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLE 1404
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 393-1181 1.21e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 1.21e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  393 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER-----AAFEELEKALSTAQKTEDAQRRMKMEMDEQMK 467
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERykelkAELRELELALLVLRLEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  468 AVERASEEERLR-LQHELSRVRQEAASMakknsEEQVAALQKlhaeELASKEQELSrRLEARERELQEQMRIALEKsrSE 546
Cdd:TIGR02168  252 EEELEELTAELQeLEEKLEELRLEVSEL-----EEEIEELQK----ELYALANEIS-RLEQQKQILRERLANLERQ--LE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  547 YLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKH 626
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  627 NKELTALaeqhRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkekeslfqahiqdmnEKTLEKLDK 706
Cdd:TIGR02168  399 NNEIERL----EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL----------------EELQEELER 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  707 KQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRR-----HHQRE----VGSISEQ---------- 767
Cdd:TIGR02168  459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGvkallKNQSGlsgiLGVLSELisvdegyeaa 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  768 ---------QELTVRRAEKALKD---------------ELSRL-GALLDERDEHLRERQARVQDLEAHLQKSAGE----- 817
Cdd:TIGR02168  539 ieaalggrlQAVVVENLNAAKKAiaflkqnelgrvtflPLDSIkGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  818 ------------LQQALAKLDLLHSEQSAAREQA------GAYEEQLAQMQQKVLDLETEKSLLTKQVVEMEthkkhvcE 879
Cdd:TIGR02168  619 syllggvlvvddLDNALELAKKLRPGYRIVTLDGdlvrpgGVITGGSAKTNSSILERRREIEELEEKIEELE-------E 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  880 ELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEESI 959
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAEIEELEERL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  960 silhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEkqfnaQILEMAQANSAGISDTVS 1039
Cdd:TIGR02168  771 ----EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-----ERLESLERRIAATERRLE 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1040 RLE---ENQRQQIESLTGAhQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVAR 1116
Cdd:TIGR02168  842 DLEeqiEELSEDIESLAAE-IEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992 1117 LKEAVSGQDVALAGLQGQLEQksaVIVSLSERESQLQSQVEKLEADLGCSLSEklsLQEELAELK 1181
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDN---LQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978
PTZ00121 PTZ00121
MAEBL; Provisional
 379-1069 3.00e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.41  E-value: 3.00e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  379 RLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTtQGEELREQKEKSERAafeELEKALSTAQKTEDAQRRM 458
Cdd:PTZ00121  1189 KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK-KAEEAKKDAEEAKKA---EEERNNEEIRKFEEARMAH 1264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  459 KMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQmri 538
Cdd:PTZ00121  1265 FARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEA--- 1341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  539 aleKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTrilelETSLEKSLQESKTQSEHLAVh 618
Cdd:PTZ00121  1342 ---KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK-----ADEAKKKAEEDKKKADELKK- 1412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  619 lEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAvEELREKYQQEKDALLKEKESlfqahiqdMNE 698
Cdd:PTZ00121  1413 -AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA-EEAKKKAEEAKKADEAKKKA--------EEA 1482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  699 KTLEKLDKKQMELESVSSELSEALRARDQlaeelsvlrgdADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKA 778
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADEAKKAAEAKKK-----------ADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADEL 1551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  779 LKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLET 858
Cdd:PTZ00121  1552 KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE 1631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  859 EKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSlaqlqdSQLKNSTVEKEQARQSLMEKeniilqmr 938
Cdd:PTZ00121  1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA------EEAKKAEEDEKKAAEALKKE-------- 1697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  939 EEQAKEIEILKQTLSSKEesisilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLldQEAKLKKELENTVLELSQKEKQ 1018
Cdd:PTZ00121  1698 AEEAKKAEELKKKEAEEK-------KKAEELKKAEEENKIKAEEAKKEAEEDKKKA--EEAKKDEEEKKKIAHLKKEEEK 1768

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907198992 1019 fnaQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEK 1069
Cdd:PTZ00121  1769 ---KAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 580-1220 3.99e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 78.62  E-value: 3.99e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  580 LQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaekNKHNKELTALAEQHRTEVEGLQQQQDSLWTERlQSL 659
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLL-------QQHQDRIEQLISEHEVEITGLTEKASSARSQA-NSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  660 SQQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRG 737
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQE----SG 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  738 DADKMKQALEAELeeqrrhHQREvgsiseqQELTVRRAE-KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAG 816
Cdd:pfam15921  374 NLDDQLQKLLADL------HKRE-------KELSLEKEQnKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  817 ELQqalakldllhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLlTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 896
Cdd:pfam15921  441 ECQ--------------------GQMERQMAAIQGKNESLEKVSSL-TAQLESTKEMLRKVVEELTAKKMTLESSERTVS 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  897 EL----EEKVRSLaqlqdsQLKNSTVEKEQARQSLMEKENIILQMREEQAK----EIEILKQTLSSKEESISILHEEyet 968
Cdd:pfam15921  500 DLtaslQEKERAI------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqtECEALKLQMAEKDKVIEILRQQ--- 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  969 kfknqekrMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ----------KEKQFNAQI--LEMAQANSAGISD 1036
Cdd:pfam15921  571 --------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdaKIRELEARVsdLELEKVKLVNAGS 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1037 TVSRLEENQRQQIESLTGAHQRKLDDVieaweKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEElTKEVAR 1116
Cdd:pfam15921  643 ERLRAVKDIKQERDQLLNEVKTSRNEL-----NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQ-TRNTLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1117 LKEAVSGQDVALA-GLQGQLEQKSAVIVSL----------------------------SERESQLQSQVEKLEADLGCSL 1167
Cdd:pfam15921  717 SMEGSDGHAMKVAmGMQKQITAKRGQIDALqskiqfleeamtnankekhflkeeknklSQELSTVATEKNKMAGELEVLR 796

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907198992 1168 SEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE 1220
Cdd:pfam15921  797 SQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1024-1718 1.80e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 1.80e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1024 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1098
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1099 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1178
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1179 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1258
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1259 SRDKAD----AILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1334
Cdd:TIGR02168  420 QQEIEEllkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1335 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1404
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1405 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1460
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1461 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1524
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1525 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1591
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1592 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1671
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198992 1672 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1718
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1494-2162 1.92e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.92e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1494 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1573
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1574 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1653
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1654 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1733
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1734 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1810
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1811 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1863
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1864 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1926
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1927 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 2006
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2007 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2086
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2087 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2161
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907198992 2162 A 2162
Cdd:TIGR02168  910 R 910
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1855-2159 2.68e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 2.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1855 QKTLQEKELTCQALEQRVKELESDLVRErgahrlEVEKLTLKYEKSQSSQQEMdgENKCVEVLEDRPEENSQSHEIQSNV 1934
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEA------ELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1935 GTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQEldilkreceQEAEEKLKQEQEDLELKHTSTLKQLM 2014
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL---------EEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2015 REFNTQLAQKEQELERtvQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQ 2094
Cdd:COG1196    362 EAEEALLEAEAELAEA--EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992 2095 TQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2159
Cdd:COG1196    440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
PTZ00121 PTZ00121
MAEBL; Provisional
 1445-2161 5.29e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 5.29e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1445 SKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEME 1523
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1524 VRKSKMEKKEcdlETALKTQTAR-VVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVRE 1602
Cdd:PTZ00121  1163 ARKAEEARKA---EDAKKAEAARkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1603 AE----ETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQkiaAIRKQLLSQM 1678
Cdd:PTZ00121  1240 EEakkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE---AKKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1679 EEKTQRYAKDTENRLSELSAQLKEREKQvhslEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERL 1758
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1759 CMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETG 1838
Cdd:PTZ00121  1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1839 NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1918
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1919 dRPEENSQSHEIQSnvgtVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-EKLKQ 1997
Cdd:PTZ00121  1553 -KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1998 EQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE---AELLESHQEETQQLHRKIAEKEDDLRRTA-- 2072
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEel 1707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2073 -------RRYEEILDAREEEMTGKVTDLQTQLEElQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELR 2145
Cdd:PTZ00121  1708 kkkeaeeKKKAEELKKAEEENKIKAEEAKKEAEE-DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                          730
                   ....*....|....*.
gi 1907198992 2146 EQVHNLEDRLKRYEKN 2161
Cdd:PTZ00121  1787 EEDEKRRMEVDKKIKD 1802
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1290-1718 1.35e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1290 QVSELEAQLTQLTEEQRTLKSSFQQVTNQL---EEKEKQIKTMKADIEGL-------LTEKEALQQEGGQQRQAASEKES 1359
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLretiaetEREREELAEEVRDLRERLEELEE 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1360 CITQLKKELA---ENINAVTLLREELSEKKSEIA-SLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQ 1435
Cdd:PRK02224   294 ERDDLLAEAGlddADAEAVEARREELEDRDEELRdRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1436 ELSLKVDAlSKEKMSALE-QVDHWSNKFS---EWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLlKEDLDRQ 1511
Cdd:PRK02224   374 EAREAVED-RREEIEELEeEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1512 NKKFECLK-----------GEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQrKKEVESLNETLKNYNQQRDTEHS 1580
Cdd:PRK02224   452 GKCPECGQpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1581 GLVQRLQHLEEL----------GEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNsSVKSRDGELKALEDKLE 1650
Cdd:PRK02224   531 TIEEKRERAEELreraaeleaeAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIE 609

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992 1651 LESAAKVELKRKAEQKiaaiRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1718
Cdd:PRK02224   610 RLREKREALAELNDER----RERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
998-1402 1.50e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  998 EAKLKKELENTVLELSQKEKQFNAQIlemaqansagisdtvSRLEENQRQQIESLTgahqrKLDDVIEAWEKKLsqqaae 1077
Cdd:PRK02224   197 EEKEEKDLHERLNGLESELAELDEEI---------------ERYEEQREQARETRD-----EADEVLEEHEERR------ 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1078 lrdkhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1157
Cdd:PRK02224   251 ------EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1158 KLEADL-------GCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSL------ 1224
Cdd:PRK02224   325 ELRDRLeecrvaaQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdap 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1225 ----NLKSLLEELASQLD-----------------SRCERTKALLEA----------KTNELVCT---SRDKADAILARL 1270
Cdd:PRK02224   405 vdlgNAEDFLEELREERDelrereaeleatlrtarERVEEAEALLEAgkcpecgqpvEGSPHVETieeDRERVEELEAEL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1271 SQCQRHTATVgEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ 1350
Cdd:PRK02224   485 EDLEEEVEEV-EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992 1351 RQAASEKESCITQLKKELAENINAVTLLR------EELSEKKSEIASLSKQLSDLGAQ 1402
Cdd:PRK02224   564 EEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAEL 621
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2187-2230 3.62e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.45  E-value: 3.62e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907198992  2187 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2230
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 858-1673 5.65e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 5.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  858 TEKSLLTKQVVEMETHKKHVceeldaQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQM 937
Cdd:pfam15921   49 TQIPIFPKYEVELDSPRKII------AYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  938 REEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLkKELENTVLELSQKEK 1017
Cdd:pfam15921  123 QMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVL-QEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1018 QFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGaHQRKLDDVIEAWEKKLSQQAAELRDKHAEQME----EKEQGL 1093
Cdd:pfam15921  202 KKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG-RIFPVEDQLEALKSESQNKIELLLQQHQDRIEqlisEHEVEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1094 GELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVS-LSERESQLQSQVEKLEADLGCSLSEKLS 1172
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSeLREAKRMYEDKIEELEKQLVLANSELTE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1173 LQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckSLHELSKKSLEDKSLNLKSLLEELASQLDSR---CERTKALLE 1249
Cdd:pfam15921  361 ARTERDQFSQESGNLDDQLQKLLADLHKREKEL----SLEKEQNKRLWDRDTGNSITIDHLRRELDDRnmeVQRLEALLK 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1250 AKTNELVCTSRDKADAILARLSQCQRHTATVGE-----ALLRRMgqVSELEAQLTQLTEEQRT---LKSSFQQVTNQLEE 1321
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQlestkEMLRKV--VEELTAKKMTLESSERTvsdLTASLQEKERAIEA 514

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1322 KEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitqLKKELAENINAVTLLREELSEKKSEIASLSKQLSDL-- 1399
Cdd:pfam15921  515 TNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEA----LKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqv 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1400 -GAQLESSISpsdkaeaisalskqheeqelqlqaQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQS 1478
Cdd:pfam15921  591 eKAQLEKEIN------------------------DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR 646

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1479 TIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1558
Cdd:pfam15921  647 AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM 726

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1559 KEVESLNETLKNYNQQRDtehsGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSS---V 1635
Cdd:pfam15921  727 KVAMGMQKQITAKRGQID----ALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQerrL 802

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1907198992 1636 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQ 1673
Cdd:pfam15921  803 KEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQ 840
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1190-1718 1.66e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1190 RVSELTGQVQAAEK--ELQSCKSLHELSKKSLEDKSLNLK-SLLEELASQLDSRCERTKALLEAKTNEL------VCTSR 1260
Cdd:COG1196    201 QLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELeelrleLEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1261 DKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKssfqqvtNQLEEKEKQIKTMKADIEGLLTEK 1340
Cdd:COG1196    281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1341 EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISpsdKAEAISALS 1420
Cdd:COG1196    354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1421 KQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQStiKDLQAQLDVKATDAREKEEQ 1500
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1501 ICLLKEDLDRQNKKFECLKGEMEVRKSkmekkecdLETALktQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT--- 1577
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAA--------YEAAL--EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflp 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1578 ----EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGEL-KALEDKLELE 1652
Cdd:COG1196    579 ldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLReVTLEGEGGSA 658

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198992 1653 SAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1718
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1320-2115 2.86e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.05  E-value: 2.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1320 EEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAAS----EKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQ 1395
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKlkeqAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1396 LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQ 1475
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1476 HQSTIKDLQAQLDVKATDAREKEEQICLLKEdldrQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVT 1555
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEE----EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1556 QRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSV 1635
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1636 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLK 1715
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1716 NLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCT--HKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRA 1793
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVleIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1794 LSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVK 1873
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1874 ELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAER 1953
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEE 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1954 DKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQ 2033
Cdd:pfam02463  802 ELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2034 ETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 2113
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER 961


                   ..
gi 1907198992 2114 TK 2115
Cdd:pfam02463  962 NK 963
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2188-2227 1.58e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.88  E-value: 1.58e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907198992 2188 TEFEYLRKVMFEYMMGRET---KTMAKVITTVLKFPDDQAQKI 2227
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1463-2160 6.77e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.43  E-value: 6.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1463 SEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKeeqicllKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALkt 1542
Cdd:pfam02463  175 LKKLIEETENLAELIIDLEELKLQELKLKEQAKKA-------LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL-- 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1543 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKdNKVREAEETVLRLREHVSSLEAELG 1622
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK-SELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1623 TVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEK--TQRYAKDTENRLSELSAQL 1700
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESerLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1701 KEREKQVHSLEDKL-----KNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRL 1775
Cdd:pfam02463  405 KEAQLLLELARQLEdllkeEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1776 EQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVsqPMGEETGNNTGVKQNWASVVDSVQ 1855
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAV--ENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1856 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYE-KSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNV 1934
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1935 GTVDGLR--SDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 2012
Cdd:pfam02463  643 AKESGLRkgVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2013 LMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTD 2092
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992 2093 LQTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEK 2160
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 607-851 2.12e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  607 ESKTQSEHLAVHLE---AEKNKHNKELTALAEQHRTEVEGlQQQQDSLWTERLQSLSQQHQAaveeLREKYQQEKDALLK 683
Cdd:NF012221  1539 ESSQQADAVSKHAKqddAAQNALADKERAEADRQRLEQEK-QQQLAAISGSQSQLESTDQNA----LETNGQAQRDAILE 1613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  684 EKESlFQAHIQDMNeKTLEKLDkkqmELESVSSELSEalRARDQLAEE-LSVLRGDADKMKQALEAELEEQRRHH---QR 759
Cdd:NF012221  1614 ESRA-VTKELTTLA-QGLDALD----SQATYAGESGD--QWRNPFAGGlLDRVQEQLDDAKKISGKQLADAKQRHvdnQQ 1685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  760 EVGSISEQQELTVRRAEKalkdelSRLGALLDERDEHlreRQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 839
Cdd:NF012221  1686 KVKDAVAKSEAGVAQGEQ------NQANAEQDIDDAK---ADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                          250
                   ....*....|..
gi 1907198992  840 GAyEEQLAQMQQ 851
Cdd:NF012221  1757 AA-ENKANQAQA 1767
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1938-2048 6.10e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 6.10e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  1938 DGLRSDLESKLTGAERDKQKLSKE-------VARLQKELRALRREHQQeLDILKRECEQEAEEKLKQEQEDLElkhtSTL 2010
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKElellnsiKPKLRDRKDALEEELRQ-LKQLEDELEDCDPTELDRAKEKLK----KLL 217

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 1907198992  2011 KQLMREFN--TQLAQKEQELERTVQETIDKAQEVEAELLE 2048
Cdd:smart00787  218 QEIMIKVKklEELEEELQELESKIEDLTNKKSELNTEIAE 257
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
241-519 6.11e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 6.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  241 RRISELREELQMDQQAKKHLQDEFDACLEEKDQyisvLQTQVSLLKQRLQNGPMNVDAPkplppgELQAEVHgdtekmEG 320
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDA----LQERREALQRLAEYSWDEIDVA------SAEREIA------EL 673

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  321 VGEPVGGGTSAKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETkRQMLE 400
Cdd:COG4913    674 EAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL-RALLE 752

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  401 TLELKEDEIAQLRSHIKQMTTQGEELREQKEKSEraafEELEKALStaqkteDAQRRMKMEMDEQMKAVERASE-EERLR 479
Cdd:COG4913    753 ERFAAALGDAVERELRENLEERIDALRARLNRAE----EELERAMR------AFNREWPAETADLDADLESLPEyLALLD 822

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1907198992  480 --LQHELSRVRQEAASMAKKNSEEQVAALQ-KLHAEELASKEQ 519
Cdd:COG4913    823 rlEEDGLPEYEERFKELLNENSIEFVADLLsKLRRAIREIKER 865
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 406-987 4.01e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.63  E-value: 4.01e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  406 EDEIAQLRSHIKQMTTQGE------ELREQKEKSE-RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 477
Cdd:COG1196    192 EDILGELERQLEPLERQAEkaeryrELKEELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  478 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 557
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  558 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 637
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  638 RTEVEGLQQQQDSL-----WTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHiqdmNEKTLEKLDKKQMELE 712
Cdd:COG1196    431 AELEEEEEEEEEALeeaaeEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA----ARLLLLLEAEADYEGF 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  713 SVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALL 790
Cdd:COG1196    507 LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARA 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  791 DERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEM 870
Cdd:COG1196    587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SL 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  871 ETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQ 950
Cdd:COG1196    663 TGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1907198992  951 TLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 987
Cdd:COG1196    743 EEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 698-1304 1.85e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.85e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  698 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 775
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  776 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 855
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  856 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 935
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  936 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 1014
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1015 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1090
Cdd:COG1196    487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1091 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1170
Cdd:COG1196    567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1171 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1250
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198992 1251 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1304
Cdd:COG1196    720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 698-1404 3.01e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.52  E-value: 3.01e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  698 EKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRGDADKMkQALEAELEEQRRHHQREVGSISEQQELTVRRAEK 777
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  778 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 856
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  857 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ----RSELEEKVRSLAQLQDsQLKNSTVEKEQA---RQSLME 929
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEledlRAELEEVDKEFAETRD-ELKDYREKLEKLkreINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  930 KENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA---KLKKELE 1006
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1007 NTVLELSQKEKQ---------FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 1077
Cdd:TIGR02169  487 KLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1078 LRDKHA--------EQMEEKEQGLGELRQK------VRIVQSEKEELTKEVARLKEAVSGQDVALA----------GLQG 1133
Cdd:TIGR02169  567 LKRRKAgratflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAArrlmgkyrmvTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1134 QLEQKSAVIVSLSERESQLQS-------QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1206
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1207 SCKSLHELSK----------KSLEDKSLNLKSLLEELASQLDSRcERTKALLEAKTNELvctsrdKADAILARLSQCQRH 1276
Cdd:TIGR02169  727 QLEQEEEKLKerleeleedlSSLEQEIENVKSELKELEARIEEL-EEDLHKLEEALNDL------EARLSHSRIPEIQAE 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1277 TATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASE 1356
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198992 1357 KESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLE 1404
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 575-1412 1.56e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 1.56e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  575 ESENKLQElgqeAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALA---EQHRTEVEGLQQQQDSL 651
Cdd:TIGR02168  176 ETERKLER----TRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVlrlEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  652 WTER--LQSLSQQHQAAVEELReKYQQEKDALLKEKESLFQAHIQDMNEKTL------EKLDKKQMELESVSSELSEALR 723
Cdd:TIGR02168  252 EEELeeLTAELQELEEKLEELR-LEVSELEEEIEELQKELYALANEISRLEQqkqilrERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  724 ARDQLAEELsvlrgdadkmkQALEAELEEQRRHHQREVGSISEQQELTV--RRAEKALKDELSRLGALLDERDEHLRERQ 801
Cdd:TIGR02168  331 KLDELAEEL-----------AELEEKLEELKEELESLEAELEELEAELEelESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  802 ARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAR-----EQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKH 876
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  877 VCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNS----------TVEKEQARQ---SLMEKENIILQMREEQAK 943
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSgilgvlseliSVDEGYEAAieaALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  944 E-IEILKQTLSSKE---ESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL----------------LDQEAKLKK 1003
Cdd:TIGR02168  560 KaIAFLKQNELGRVtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1004 ELENTVLELSQKEKQFNAQILeMAQANSAGISDTVSRLEE--NQRQQIESLTGAhQRKLDDVIEAWEKKLSQQAAELRDK 1081
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGGV-ITGGSAKTNSSILERRREieELEEKIEELEEK-IAELEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1082 HAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEA 1161
Cdd:TIGR02168  718 RKE-LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1162 DLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckslhELSKKSLEDKSLNLKSLLEELASqldsrc 1241
Cdd:TIGR02168  797 ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL-------EDLEEQIEELSEDIESLAAEIEE------ 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1242 ertkalLEAKTNELvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEE 1321
Cdd:TIGR02168  864 ------LEELIEEL----ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1322 KEKQIKTMKADI--EGLLTEKEALQQEGGQQRQAASEKEScITQLKKELAE----NINAVtllrEELSEKKSEIASLSKQ 1395
Cdd:TIGR02168  934 LEVRIDNLQERLseEYSLTLEEAEALENKIEDDEEEARRR-LKRLENKIKElgpvNLAAI----EEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|
gi 1907198992 1396 LSDLG---AQLESSISPSDK 1412
Cdd:TIGR02168 1009 KEDLTeakETLEEAIEEIDR 1028
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 461-1053 2.56e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 92.31  E-value: 2.56e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  461 EMDEQMKAVERASE--EERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLhAEELASKEQELSRRLEARERELQE---- 534
Cdd:COG1196    197 ELERQLEPLERQAEkaERYRELKEELKELEAELLLLKLRELEAELEELEAE-LEELEAELEELEAELAELEAELEElrle 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  535 --QMRIALEKSRSEYLKLTQEKEQ--QESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKT 610
Cdd:COG1196    276 leELELELEEAQAEEYELLAELARleQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  611 QSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLfq 690
Cdd:COG1196    356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL-- 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  691 ahiqdmnektLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadkmkqALEAELEEQRRHHQREVGSISEQQEL 770
Cdd:COG1196    434 ----------EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL--------EEAALLEAALAELLEELAEAAARLLL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  771 TVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQ 850
Cdd:COG1196    496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  851 QKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEK 930
Cdd:COG1196    576 FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  931 ENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVL 1010
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE 735

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907198992 1011 ELSQKEKQFNAQILEMAQANSAGISDtvsrlEENQRQQIESLT 1053
Cdd:COG1196    736 ELLEELLEEEELLEEEALEELPEPPD-----LEELERELERLE 773
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 334-899 5.83e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.15  E-value: 5.83e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  334 LEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKmkgmvITETKRQMLETLELKEDEIAQLR 413
Cdd:COG1196    227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-----LELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  414 SHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAAS 493
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  494 MAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEylkLTQEKEQQESLALEELELQKKAIL 573
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE---EEEEEEEEALEEAAEEEAELEEEE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  574 TESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWT 653
Cdd:COG1196    459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  654 ERLQSLSQQHQAAVEELREKYQQEKDALLKEKES--LFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEE 731
Cdd:COG1196    539 ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGraTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVL 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  732 LSVLRGDADKmKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKAlkDELSRLGALLDERDEHLRERQARVQDLEAHL 811
Cdd:COG1196    619 GDTLLGRTLV-AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG--GSRRELLAALLEAEAELEELAERLAEEELEL 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  812 QKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKhvcEELDAQRAQVQQL 891
Cdd:COG1196    696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP---PDLEELERELERL 772


                   ....*...
gi 1907198992  892 ERQRSELE 899
Cdd:COG1196    773 EREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 393-1181 1.21e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 1.21e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  393 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER-----AAFEELEKALSTAQKTEDAQRRMKMEMDEQMK 467
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERykelkAELRELELALLVLRLEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  468 AVERASEEERLR-LQHELSRVRQEAASMakknsEEQVAALQKlhaeELASKEQELSrRLEARERELQEQMRIALEKsrSE 546
Cdd:TIGR02168  252 EEELEELTAELQeLEEKLEELRLEVSEL-----EEEIEELQK----ELYALANEIS-RLEQQKQILRERLANLERQ--LE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  547 YLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKH 626
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  627 NKELTALaeqhRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkekeslfqahiqdmnEKTLEKLDK 706
Cdd:TIGR02168  399 NNEIERL----EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL----------------EELQEELER 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  707 KQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRR-----HHQRE----VGSISEQ---------- 767
Cdd:TIGR02168  459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGvkallKNQSGlsgiLGVLSELisvdegyeaa 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  768 ---------QELTVRRAEKALKD---------------ELSRL-GALLDERDEHLRERQARVQDLEAHLQKSAGE----- 817
Cdd:TIGR02168  539 ieaalggrlQAVVVENLNAAKKAiaflkqnelgrvtflPLDSIkGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  818 ------------LQQALAKLDLLHSEQSAAREQA------GAYEEQLAQMQQKVLDLETEKSLLTKQVVEMEthkkhvcE 879
Cdd:TIGR02168  619 syllggvlvvddLDNALELAKKLRPGYRIVTLDGdlvrpgGVITGGSAKTNSSILERRREIEELEEKIEELE-------E 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  880 ELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEESI 959
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAEIEELEERL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  960 silhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEkqfnaQILEMAQANSAGISDTVS 1039
Cdd:TIGR02168  771 ----EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-----ERLESLERRIAATERRLE 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1040 RLE---ENQRQQIESLTGAhQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVAR 1116
Cdd:TIGR02168  842 DLEeqiEELSEDIESLAAE-IEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992 1117 LKEAVSGQDVALAGLQGQLEQksaVIVSLSERESQLQSQVEKLEADLGCSLSEklsLQEELAELK 1181
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDN---LQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 766-1712 1.73e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 1.73e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  766 EQQELTVRRAEKALKDeLSRLGALLDERDEHLR--ERQARVQDLEAHLQKSAGELQQALAKLDLLhseqsAAREQAGAYE 843
Cdd:TIGR02168  172 ERRKETERKLERTREN-LDRLEDILNELERQLKslERQAEKAERYKELKAELRELELALLVLRLE-----ELREELEELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  844 EQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQlQDSQLKNSTVEKEQA 923
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE-RLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  924 RQSLMEKENIILQMREEQAKEIEILKQTLsskeESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 1003
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEEL----ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1004 ELENTVLELSQKEkqfnaqilEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKkLSQQAAELRdkha 1083
Cdd:TIGR02168  401 EIERLEARLERLE--------DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELER-LEEALEELR---- 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1084 EQMEEKEQGLGELRQKVRIVQSEKEELtkevARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSER---ESQLQSQVEK-L 1159
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAaL 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1160 EADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTG----QVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAS 1235
Cdd:TIGR02168  544 GGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1236 QLdsrcertkalleaktneLVCTSRDKADAILARLSQCQRHTATVGEaLLRRMGQVSELEAQLTQLTEEQRtlkssfqqv 1315
Cdd:TIGR02168  624 GV-----------------LVVDDLDNALELAKKLRPGYRIVTLDGD-LVRPGGVITGGSAKTNSSILERR--------- 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1316 tNQLEEKEKQIKTMKADIEGLLTEKEALqqeggqqRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQ 1395
Cdd:TIGR02168  677 -REIEELEEKIEELEEKIAELEKALAEL-------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1396 LSDLGAQLEssispsdKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQ 1475
Cdd:TIGR02168  749 IAQLSKELT-------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1476 HQSTIKDLQAQLDVKATDAREKEEQICLLKEDLdrqnkkfECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEdcvt 1555
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDI-------ESLAAEIEELEELIEELESELEALLNERASLEEALA---- 890

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1556 QRKKEVESLNETLKNYNQQRDTehsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLeaelgtVKKELEHVNSSV 1635
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSE----LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE------YSLTLEEAEALE 960

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907198992 1636 KSRDGELKALEDKLelesaakvelkRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLED 1712
Cdd:TIGR02168  961 NKIEDDEEEARRRL-----------KRLENKIKELGPVNLAAIEE-----YEELKERYDFLTAQKEDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 885-1717 7.64e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.34  E-value: 7.64e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  885 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQaKEIEILKQTLSSKEESISILHE 964
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEEL-EELTAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  965 EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQansagisdtvsrleen 1044
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE---------------- 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1045 QRQQIESLTGAHQRKLDDVIEAWEKklsQQAAELRdkhaeqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQ 1124
Cdd:TIGR02168  342 LEEKLEELKEELESLEAELEELEAE---LEELESR------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1125 DVALAGLQGQLEQKSAVIVSLSEREsqLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKE 1204
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1205 LQSCKSLHEL------SKKSLEDKSLNLKSLLEELASQLDSRCERTKAL---LEAKTNELVCTSRDKADAILARLSQCQR 1275
Cdd:TIGR02168  491 LDSLERLQENlegfseGVKALLKNQSGLSGILGVLSELISVDEGYEAAIeaaLGGRLQAVVVENLNAAKKAIAFLKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1276 HTATVGEALLRRmgqvselEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQ--- 1352
Cdd:TIGR02168  571 GRVTFLPLDSIK-------GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlrp 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1353 --------------------AASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDK 1412
Cdd:TIGR02168  644 gyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1413 AEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKAT 1492
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1493 DAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYN 1572
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1573 QQRdtehsglvQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgelkaledklele 1652
Cdd:TIGR02168  884 SLE--------EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE----------------------- 932

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992 1653 saakvelkrKAEQKIAairkQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNL 1717
Cdd:TIGR02168  933 ---------GLEVRID----NLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 379-1069 3.00e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.41  E-value: 3.00e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  379 RLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTtQGEELREQKEKSERAafeELEKALSTAQKTEDAQRRM 458
Cdd:PTZ00121  1189 KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK-KAEEAKKDAEEAKKA---EEERNNEEIRKFEEARMAH 1264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  459 KMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQmri 538
Cdd:PTZ00121  1265 FARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEA--- 1341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  539 aleKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTrilelETSLEKSLQESKTQSEHLAVh 618
Cdd:PTZ00121  1342 ---KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK-----ADEAKKKAEEDKKKADELKK- 1412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  619 lEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAvEELREKYQQEKDALLKEKESlfqahiqdMNE 698
Cdd:PTZ00121  1413 -AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA-EEAKKKAEEAKKADEAKKKA--------EEA 1482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  699 KTLEKLDKKQMELESVSSELSEALRARDQlaeelsvlrgdADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKA 778
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADEAKKAAEAKKK-----------ADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADEL 1551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  779 LKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLET 858
Cdd:PTZ00121  1552 KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE 1631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  859 EKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSlaqlqdSQLKNSTVEKEQARQSLMEKeniilqmr 938
Cdd:PTZ00121  1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA------EEAKKAEEDEKKAAEALKKE-------- 1697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  939 EEQAKEIEILKQTLSSKEesisilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLldQEAKLKKELENTVLELSQKEKQ 1018
Cdd:PTZ00121  1698 AEEAKKAEELKKKEAEEK-------KKAEELKKAEEENKIKAEEAKKEAEEDKKKA--EEAKKDEEEKKKIAHLKKEEEK 1768

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907198992 1019 fnaQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEK 1069
Cdd:PTZ00121  1769 ---KAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 402-1122 3.06e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 3.06e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  402 LELKEDEIAQLRSHIKQMTTQGEELREQKEKSE------RAAFEELEKALSTAQKTEDAQR-------RMKMEMDEQMKA 468
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEekleelRLEVSELEEEIEELQKELYALAneisrleQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  469 VER---ASEEERLRLQHELSRVRQEAASMAKKNSE--EQVAALQKLHaEELASKEQELSRRLEARERELQE------QMR 537
Cdd:TIGR02168  314 LERqleELEAQLEELESKLDELAEELAELEEKLEElkEELESLEAEL-EELEAELEELESRLEELEEQLETlrskvaQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  538 IALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE------KSLQESKTQ 611
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELErleealEELREELEE 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  612 SEHLAVHLEAEKNKHNKELTALaEQHRTEVEGLQQQQDSLWTERLQsLSQQHQAAVE--ELREKYQQEKDALLKE----- 684
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG-LSGILGVLSEliSVDEGYEAAIEAALGGrlqav 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  685 ----------------KESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGD-------ADK 741
Cdd:TIGR02168  551 vvenlnaakkaiaflkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvVDD 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  742 MKQALEaeleeQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALldERDEHLRERQARVQDLEAHLQKSAGELQQA 821
Cdd:TIGR02168  631 LDNALE-----LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSIL--ERRREIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  822 LAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEK 901
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  902 VRSLAQLQDSQLKNSTVEKEQ-------------ARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYEt 968
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREAldelraeltllneEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE- 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  969 kfkNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNA--QILEMAQANSAGISDTVSRLEENQR 1046
Cdd:TIGR02168  863 ---ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSElrRELEELREKLAQLELRLEGLEVRID 939

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1047 QQIESLTGAHQRKLDDVIEAWEKKLSQQaAELRDKhAEQMEEKEQGLG-----------ELRQKVRIVQSEKEELTKEVA 1115
Cdd:TIGR02168  940 NLQERLSEEYSLTLEEAEALENKIEDDE-EEARRR-LKRLENKIKELGpvnlaaieeyeELKERYDFLTAQKEDLTEAKE 1017


                   ....*..
gi 1907198992 1116 RLKEAVS 1122
Cdd:TIGR02168 1018 TLEEAIE 1024
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 580-1220 3.99e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 78.62  E-value: 3.99e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  580 LQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaekNKHNKELTALAEQHRTEVEGLQQQQDSLWTERlQSL 659
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLL-------QQHQDRIEQLISEHEVEITGLTEKASSARSQA-NSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  660 SQQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRG 737
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQE----SG 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  738 DADKMKQALEAELeeqrrhHQREvgsiseqQELTVRRAE-KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAG 816
Cdd:pfam15921  374 NLDDQLQKLLADL------HKRE-------KELSLEKEQnKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  817 ELQqalakldllhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLlTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 896
Cdd:pfam15921  441 ECQ--------------------GQMERQMAAIQGKNESLEKVSSL-TAQLESTKEMLRKVVEELTAKKMTLESSERTVS 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  897 EL----EEKVRSLaqlqdsQLKNSTVEKEQARQSLMEKENIILQMREEQAK----EIEILKQTLSSKEESISILHEEyet 968
Cdd:pfam15921  500 DLtaslQEKERAI------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqtECEALKLQMAEKDKVIEILRQQ--- 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  969 kfknqekrMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ----------KEKQFNAQI--LEMAQANSAGISD 1036
Cdd:pfam15921  571 --------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdaKIRELEARVsdLELEKVKLVNAGS 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1037 TVSRLEENQRQQIESLTGAHQRKLDDVieaweKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEElTKEVAR 1116
Cdd:pfam15921  643 ERLRAVKDIKQERDQLLNEVKTSRNEL-----NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQ-TRNTLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1117 LKEAVSGQDVALA-GLQGQLEQKSAVIVSL----------------------------SERESQLQSQVEKLEADLGCSL 1167
Cdd:pfam15921  717 SMEGSDGHAMKVAmGMQKQITAKRGQIDALqskiqfleeamtnankekhflkeeknklSQELSTVATEKNKMAGELEVLR 796

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907198992 1168 SEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE 1220
Cdd:pfam15921  797 SQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 365-1119 4.57e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.57  E-value: 4.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  365 LLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKA 444
Cdd:TIGR02169  235 LERQKEAIERQLASLEEELEKLT------------EEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAE 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  445 LSTAQKTEDAQRRMKMEMDEQMKAVEraSEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRR 524
Cdd:TIGR02169  303 IASLERSIAEKERELEDAEERLAKLE--AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  525 LEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKS 604
Cdd:TIGR02169  381 AETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQL 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  605 LQE-SKTQSEHLAvhLEAEKNKHNKELTALAEQH----------RTEVEGLQQQQDSLWTER---------LQSLSQQHQ 664
Cdd:TIGR02169  461 AADlSKYEQELYD--LKEEYDRVEKELSKLQRELaeaeaqarasEERVRGGRAVEEVLKASIqgvhgtvaqLGSVGERYA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  665 AAVEEL-----------REKYQQEKDALLKEKEsLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELS 733
Cdd:TIGR02169  539 TAIEVAagnrlnnvvveDDAVAKEAIELLKRRK-AGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFK 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  734 VLRGDA---DKMKQA-----------LEAELEEQ--------RRHHQREVGSISEQQEL-TVRRAEKALKDELSRLGALL 790
Cdd:TIGR02169  618 YVFGDTlvvEDIEAArrlmgkyrmvtLEGELFEKsgamtggsRAPRGGILFSRSEPAELqRLRERLEGLKRELSSLQSEL 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  791 DERDEHLRERQARVQDLEAHLQKSAGELQQalakldlLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEM 870
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  871 ETHKKHVCEELDA-----QRAQVQQLERQRSELEEKVRSL-AQLQ--DSQLKNSTVEKEQARQSLMEKENIILQM---RE 939
Cdd:TIGR02169  771 EEDLHKLEEALNDlearlSHSRIPEIQAELSKLEEEVSRIeARLReiEQKLNRLTLEKEYLEKEIQELQEQRIDLkeqIK 850

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  940 EQAKEIEILKQTLSSKEESIsilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQf 1019
Cdd:TIGR02169  851 SIEKEIENLNGKKEELEEEL----EELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK- 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1020 naqiLEMAQANSAGISDTVSRLEEnqrqqiESLTGAHQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQK 1099
Cdd:TIGR02169  926 ----LEALEEELSEIEDPKGEDEE------IPEEELSLEDVQAELQRVEEEI-RALEPVNMLAIQEYEEVLKRLDELKEK 994

                          810       820
                   ....*....|....*....|
gi 1907198992 1100 VRIVQSEKEELTKEVARLKE 1119
Cdd:TIGR02169  995 RAKLEEERKAILERIEEYEK 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 393-1221 5.14e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.19  E-value: 5.14e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  393 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER----------AAFEELEKALSTAQKTEDAQRRMKMEM 462
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqallkekreYEGYELLKEKEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  463 DEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHA-----EELASKEQELSRRLEARERELQE-QM 536
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGEleaeiASLERSIAEKERELEDAEERLAKlEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  537 RIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKsLQESKTQSEHLA 616
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK-LKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  617 VHLEAEKnkhnKELTALAEQHRTEVEGLQQQQDSLWTERLQSlsqqhQAAVEELREKYQQEKDALLKEKESLFQahiqdm 696
Cdd:TIGR02169  409 DRLQEEL----QRLSEELADLNAAIAGIEAKINELEEEKEDK-----ALEIKKQEWKLEQLAADLSKYEQELYD------ 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  697 nekTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadkmkqALEAELEEQRR--HHQ-REVGSISEQQELTVR 773
Cdd:TIGR02169  474 ---LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGR--------AVEEVLKASIQgvHGTvAQLGSVGERYATAIE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  774 RAEKAlkdelsRLGALLDERD-------EHLRERQA-----------RVQDLEAHLQKSAGELQQALAKLD--------- 826
Cdd:TIGR02169  543 VAAGN------RLNNVVVEDDavakeaiELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEfdpkyepaf 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  827 -------LLHSEQSAAREQAGAYeeQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELE 899
Cdd:TIGR02169  617 kyvfgdtLVVEDIEAARRLMGKY--RMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  900 EKVRSlaqlQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQtlssKEESISILHEEYEtkfkNQEKRMEK 979
Cdd:TIGR02169  695 SELRR----IENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE----LEEDLSSLEQEIE----NVKSELKE 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  980 IKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFnaqILEMAQANSAGISDTVSRLEENQrQQIESLTGAHQRK 1059
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSK---LEEEVSRIEARLREIEQKLNRLT-LEKEYLEKEIQEL 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1060 LDDVIEAWEKKLSQQAAELRDKhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKS 1139
Cdd:TIGR02169  839 QEQRIDLKEQIKSIEKEIENLN--GKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1140 AVIVSLSERESQLQSQVEKLEADLGCSLSE----------KLSLQEELAELKLLADKSQLRVSELTgQVQAAEKELQSCK 1209
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsledvQAELQRVEEEIRALEPVNMLAIQEYE-EVLKRLDELKEKR 995

                          890
                   ....*....|..
gi 1907198992 1210 SLHELSKKSLED 1221
Cdd:TIGR02169  996 AKLEEERKAILE 1007
PTZ00121 PTZ00121
MAEBL; Provisional
 424-1089 5.54e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 78.26  E-value: 5.54e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  424 EELREQKEKSERAAFEELEKA--LSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEE 501
Cdd:PTZ00121  1143 EEARKAEDAKRVEIARKAEDArkAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAED 1222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  502 QVAALQKLHAEELASKEQELSRRLEARERELQEQMRIAL--------------EKSRSEYLKLTQEKEQ-----QESLAL 562
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARmahfarrqaaikaeEARKADELKKAEEKKKadeakKAEEKK 1302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  563 EELELQKKAiltESENKLQELGQEAEAYRTRILELETSLE---KSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRT 639
Cdd:PTZ00121  1303 KADEAKKKA---EEAKKADEAKKKAEEAKKKADAAKKKAEeakKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK 1379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  640 EVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELS 719
Cdd:PTZ00121  1380 ADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA 1459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  720 EALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEltvRRAEKALKDELSRLGALLDERDEHLRE 799
Cdd:PTZ00121  1460 EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK---KKADEAKKAEEAKKADEAKKAEEAKKA 1536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  800 RQARvqdlEAHLQKSAGELQQAlakLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL-ETEKSLLTKQVVEMETHKKHVC 878
Cdd:PTZ00121  1537 DEAK----KAEEKKKADELKKA---EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAkKAEEARIEEVMKLYEEEKKMKA 1609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  879 EELDAQRAQVQQLERQRSELEEKvrslaQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEEs 958
Cdd:PTZ00121  1610 EEAKKAEEAKIKAEELKKAEEEK-----KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA- 1683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  959 isilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQAnsagisdtv 1038
Cdd:PTZ00121  1684 -----EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEA--------- 1749

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907198992 1039 sRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEK 1089
Cdd:PTZ00121  1750 -KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
PTZ00121 PTZ00121
MAEBL; Provisional
 403-1114 7.69e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.87  E-value: 7.69e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  403 ELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAafEELEKAlSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRlQH 482
Cdd:PTZ00121  1091 EATEEAFGKAEEAKKTETGKAEEARKAEEAKKKA--EDARKA-EEARKAEDARKAEEARKAEDAKRVEIARKAEDAR-KA 1166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  483 ELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERE---LQEQMRIALEKSRSEYLKLTQEKEQQES 559
Cdd:PTZ00121  1167 EEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEearKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  560 LALEELELQKKAILTESENKLQELGQEAEAYRtRILELETSLEKSLQESKTQSEHL----AVHLEAEKNKHNKELTALAE 635
Cdd:PTZ00121  1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEAR-KADELKKAEEKKKADEAKKAEEKkkadEAKKKAEEAKKADEAKKKAE 1325

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  636 QHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKYQQEKDALLK---EKESLFQAHIQDMNEKTLEKLDKKQMELE 712
Cdd:PTZ00121  1326 EAKKKADAAKKKAEEA-KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKkeeAKKKADAAKKKAEEKKKADEAKKKAEEDK 1404

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  713 SVSSELSEALRARDQLAEelsvLRGDADKMKQALEAELEEQRRHHQREVGSISEQQ---ELTVRRAEKALKDELSRLGAL 789
Cdd:PTZ00121  1405 KKADELKKAAAAKKKADE----AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkaEEAKKKAEEAKKADEAKKKAE 1480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  790 LDERDEHLRERQARVQDLEAHLQKSAGELQQA----LAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTK 865
Cdd:PTZ00121  1481 EAKKADEAKKKAEEAKKKADEAKKAAEAKKKAdeakKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKA 1560

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  866 QVVEMETHKKHVCEE--LDAQRAQV-QQLERQRSELEEKV-RSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQ 941
Cdd:PTZ00121  1561 EEKKKAEEAKKAEEDknMALRKAEEaKKAEEARIEEVMKLyEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  942 AKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENtvLELSQKEKQFNA 1021
Cdd:PTZ00121  1641 KEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE--LKKKEAEEKKKA 1718

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1022 QILEMAQANSAGISDTVSRLEENQRQQIESLTgahqrklddVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGE-LRQKV 1100
Cdd:PTZ00121  1719 EELKKAEEENKIKAEEAKKEAEEDKKKAEEAK---------KDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEeLDEED 1789

                          730
                   ....*....|....
gi 1907198992 1101 RIVQSEKEELTKEV 1114
Cdd:PTZ00121  1790 EKRRMEVDKKIKDI 1803
PTZ00121 PTZ00121
MAEBL; Provisional
 339-1100 1.48e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.10  E-value: 1.48e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  339 QRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQ 418
Cdd:PTZ00121  1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAE 1312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  419 MTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERlrlqhELSRVRQEAASMAKKN 498
Cdd:PTZ00121  1313 EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK-----KKEEAKKKADAAKKKA 1387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  499 SEEQVAALQKLHAEELASKEQELSRRLEARERElQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAiltesen 578
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELKKAAAAKKKA-DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA------- 1459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  579 klQELGQEAEAYRTrilelETSLEKSLQESKTQSEhlaVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQS 658
Cdd:PTZ00121  1460 --EEAKKKAEEAKK-----ADEAKKKAEEAKKADE---AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKK 1529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  659 LSQQHQAavEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESvsselsealrardqlaeelsvlrgd 738
Cdd:PTZ00121  1530 AEEAKKA--DEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK------------------------- 1582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  739 ADKMKQALEAELEEQRRHHQREvgsiseqqelTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGEL 818
Cdd:PTZ00121  1583 AEEAKKAEEARIEEVMKLYEEE----------KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL 1652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  819 QQAlakldllHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSEL 898
Cdd:PTZ00121  1653 KKA-------EEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAE 1725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  899 EEKVRSLAQLQDSQLKNSTvEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESisiLHEEYETKFKNQEKRME 978
Cdd:PTZ00121  1726 EENKIKAEEAKKEAEEDKK-KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE---LDEEDEKRRMEVDKKIK 1801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  979 KIKQKAKEMQE----------TKKKLLDQEAKLKKELENTVLELSQKEKQ--FNAQILEMAQANSAGISDTVSRLEENQR 1046
Cdd:PTZ00121  1802 DIFDNFANIIEggkegnlvinDSKEMEDSAIKEVADSKNMQLEEADAFEKhkFNKNNENGEDGNKEADFNKEKDLKEDDE 1881

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992 1047 QQIESLTGAHQRKLDDV-IEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKV 1100
Cdd:PTZ00121  1882 EEIEEADEIEKIDKDDIeREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREEI 1936
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1024-1718 1.80e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 1.80e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1024 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1098
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1099 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1178
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1179 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1258
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1259 SRDKAD----AILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1334
Cdd:TIGR02168  420 QQEIEEllkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1335 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1404
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1405 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1460
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1461 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1524
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1525 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1591
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1592 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1671
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198992 1672 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1718
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 197-1011 1.04e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.94  E-value: 1.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  197 LRRMERSLSSYRgKYSELVTAFQTLQREKKKLQGILS----QSQDKSLRRISELREELQMDQQAKKHLQDEFDACLEEKD 272
Cdd:TIGR02168  195 LNELERQLKSLE-RQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  273 QYISVLQTQVSLLKQRLQNgpmnvdapkplppgeLQAEVHG-DTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRC 351
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYA---------------LANEISRlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  352 KETIgshKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKR---------QMLETLELKEDEIAQLRSHIKQMTTQ 422
Cdd:TIGR02168  339 LAEL---EEKLEELKEELESLEAELEELEAELEELESRLEELEEQletlrskvaQLELQIASLNNEIERLEARLERLEDR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  423 GEELREQKEKSERAA-----------FEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEA 491
Cdd:TIGR02168  416 RERLQQEIEELLKKLeeaelkelqaeLEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  492 ASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARErELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKA 571
Cdd:TIGR02168  496 RLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE-GYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVT 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  572 IL-------TESENKLQELGQEAEAYRTRILELETSLEK----------------SLQE-----SKTQSEHLAVHLEAEK 623
Cdd:TIGR02168  575 FLpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvdDLDNalelaKKLRPGYRIVTLDGDL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  624 -------NKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDM 696
Cdd:TIGR02168  655 vrpggviTGGSAKTNSSILERRREIEELEEKIEEL-EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  697 NEKTLEKldkkqmELESVSSELSEALRARDQLAEELSVLRGDADKMKQALeAELEEQRRHHQREVGSISEQQElTVRRAE 776
Cdd:TIGR02168  734 DLARLEA------EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-AEAEAEIEELEAQIEQLKEELK-ALREAL 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  777 KALKDELSRLGALLDErdehLRERQARVQDLEAHLQKSAGELQQALAKLdllhseqsaaREQAGAYEEQLAQMQQKVLDL 856
Cdd:TIGR02168  806 DELRAELTLLNEEAAN----LRERLESLERRIAATERRLEDLEEQIEEL----------SEDIESLAAEIEELEELIEEL 871

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  857 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNS--TVEKEQARQSLMEKENI 933
Cdd:TIGR02168  872 ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELrEKLAQLELRLEglEVRIDNLQERLSEEYSL 951

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  934 ILQMREEQAKEIEI----LKQTLSSKEESISILHE---EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELE 1006
Cdd:TIGR02168  952 TLEEAEALENKIEDdeeeARRRLKRLENKIKELGPvnlAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREAR 1031


                   ....*
gi 1907198992 1007 NTVLE 1011
Cdd:TIGR02168 1032 ERFKD 1036
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1494-2162 1.92e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.92e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1494 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1573
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1574 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1653
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1654 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1733
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1734 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1810
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1811 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1863
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1864 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1926
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1927 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 2006
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2007 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2086
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2087 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2161
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907198992 2162 A 2162
Cdd:TIGR02168  910 R 910
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 867-1718 2.06e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 2.06e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  867 VVEMETHKKHVCEELDAQRaqvQQLERQRSELEEKVRSLAQLQDsqlknstvEKEQARQSLmekeniILQMREEQAKEIE 946
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVE---ENIERLDLIIDEKRQQLERLRR--------EREKAERYQ------ALLKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  947 ILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQIlEM 1026
Cdd:TIGR02169  228 LLKE-KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEI-AS 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1027 AQANSAGISDTVSRLEENQRQQIESLtgahqRKLDDVIEAWEKKLSQQAAElRDKHAEQMEEKEQGLGELRQKVRIVQSE 1106
Cdd:TIGR02169  306 LERSIAEKERELEDAEERLAKLEAEI-----DKLLAEIEELEREIEEERKR-RDKLTEEYAELKEELEDLRAELEEVDKE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1107 KEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEElaelklladk 1186
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE---------- 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1187 sqlrVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCtsRDKADAI 1266
Cdd:TIGR02169  450 ----IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVL--KASIQGV 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1267 LARLSQC----QRHTATVGEALLRRMGQV----SELEAQLTQLTEEQRTLKSSFQQVTN-QLEEKEKQIKTMKADIE--- 1334
Cdd:TIGR02169  524 HGTVAQLgsvgERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLNKmRDERRDLSILSEDGVIGfav 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1335 --------------------GLLTEKEALQQEGGQQRQAA-----SEKESCITQLKKELAENINAVTLLREELSEKKSEI 1389
Cdd:TIGR02169  604 dlvefdpkyepafkyvfgdtLVVEDIEAARRLMGKYRMVTlegelFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERL 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1390 ASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKA 1469
Cdd:TIGR02169  684 EGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1470 QSRLAQHQSTIKDLQAQL-DVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVV 1548
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1549 ELEDCVTQRKKEVESLN----------ETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLE 1618
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNgkkeeleeelEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1619 AELGTVKKELEHVNSSVKSrdgelkALEDKLELESAAKVELKRKA-EQKIAAIRKQLLSQMEEktqryAKDTENRLSELS 1697
Cdd:TIGR02169  924 AKLEALEEELSEIEDPKGE------DEEIPEEELSLEDVQAELQRvEEEIRALEPVNMLAIQE-----YEEVLKRLDELK 992

                          890       900
                   ....*....|....*....|.
gi 1907198992 1698 AQLKEREKQVHSLEDKLKNLE 1718
Cdd:TIGR02169  993 EKRAKLEEERKAILERIEEYE 1013
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 517-1349 3.17e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 3.17e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  517 KEQELSRRLEARERElqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAiLTESENKLQELGQEAEAYRTRILE 596
Cdd:TIGR02169  172 KEKALEELEEVEENI--ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYE-GYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  597 LETSLEKS---LQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREK 673
Cdd:TIGR02169  249 LEEELEKLteeISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--ERSIAEKERELEDAEERLAK 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  674 YQQEKDALLKEKESL---------FQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQ 744
Cdd:TIGR02169  327 LEAEIDKLLAEIEELereieeerkRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  745 ALEAELEEQRRHHQRevgsiseqqeltVRRAEKALKDELSRLGALlderdehlrerQARVQDLEAHLQKSAGELQQALAK 824
Cdd:TIGR02169  407 ELDRLQEELQRLSEE------------LADLNAAIAGIEAKINEL-----------EEEKEDKALEIKKQEWKLEQLAAD 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  825 LDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKslltKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEK-VR 903
Cdd:TIGR02169  464 LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA----RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyAT 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  904 SLAQLQDSQLKNSTVEKEQARQSLMEkenIILQMREEQAKEIEILKqtLSSKEESISILHEE----YETKFKNQEKRMEK 979
Cdd:TIGR02169  540 AIEVAAGNRLNNVVVEDDAVAKEAIE---LLKRRKAGRATFLPLNK--MRDERRDLSILSEDgvigFAVDLVEFDPKYEP 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  980 IKQKA------KEMQETKKKLLDQEAKLKKELEntvlelsqkekqfnaqILEMAQANSAGiSDTVSRLEENQRQQIESLt 1053
Cdd:TIGR02169  615 AFKYVfgdtlvVEDIEAARRLMGKYRMVTLEGE----------------LFEKSGAMTGG-SRAPRGGILFSRSEPAEL- 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1054 gahqRKLDDVIEAWEKKLSQQAAELRDKHAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQG 1133
Cdd:TIGR02169  677 ----QRLRERLEGLKRELSSLQSELRRIENR-LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1134 QLEQKSAVIVSLSERESQLQSQVEKLEADLGcSLSEKLSlQEELAELKLLADKSQLRVSELTGQVQAAEKELQSckslHE 1213
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALN-DLEARLS-HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNR----LT 825

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1214 LSKKSLEDKSLNLKSLLEELASQLDSRCERTKALleaktnelvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSE 1293
Cdd:TIGR02169  826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL------------NGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198992 1294 LEAQLTQLTEEQRTLKSsfqqvtnQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQ 1349
Cdd:TIGR02169  894 LEAQLRELERKIEELEA-------QIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 188-875 7.93e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 7.93e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  188 LSREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGilsqsqdkslrRISELREELQMDQQAKKHLQDEFDAC 267
Cdd:COG1196    225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEA-----------ELEELRLELEELELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  268 LEEKDQyisvLQTQVSLLKQRLQNgpmnvdapkplppgelqaevhgdtekmegvgepvgggtsaktlemLQQRVKRQEnl 347
Cdd:COG1196    294 LAELAR----LEQDIARLEERRRE---------------------------------------------LEERLEELE-- 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  348 lqrcketigshkEQCALLLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDEIAQLRSHIKQMTTQGEELR 427
Cdd:COG1196    323 ------------EELAELEEELEELEEELEELEEELEEAE------------EELEEAEAELAEAEEALLEAEAELAEAE 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  428 EQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQmkaveRASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQ 507
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERL-----ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  508 KLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEA 587
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  588 EAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAV 667
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  668 EELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKL-------DKKQMELESVSSELSEALRARDQLAEELSVLRGDAD 740
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTlegeggsAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  741 KMKQALEAELEEQRRHHQREVgsISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQ 820
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEE--ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992  821 ALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKK 875
Cdd:COG1196    772 LEREIEALGPVNLLAIEEYEELEERYDFLSEQREDLEEARETLEEAIEEIDRETR 826
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 365-1113 2.12e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 66.53  E-value: 2.12e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  365 LLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELRE-QKEKSERAAFEELEK 443
Cdd:pfam02463  178 LIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlQELLRDEQEEIESSK 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  444 ALSTAQKTEDAQRRMKMEMDEQ------MKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASK 517
Cdd:pfam02463  258 QEIEKEEEKLAQVLKENKEEEKekklqeEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEI 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  518 EQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILEL 597
Cdd:pfam02463  338 EELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  598 ETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQE 677
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  678 KDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHH 757
Cdd:pfam02463  498 RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  758 QREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAARE 837
Cdd:pfam02463  578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEG 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  838 QAgAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNST 917
Cdd:pfam02463  658 LA-EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINE 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  918 VEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMeKIKQKAKEMQETKKKLLDQ 997
Cdd:pfam02463  737 ELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKL-KAQEEELRALEEELKEEAE 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  998 EAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 1077
Cdd:pfam02463  816 LLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKE 895

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 1907198992 1078 LRDKHaEQMEEKEQGLGELRQKVRIVQSEKEELTKE 1113
Cdd:pfam02463  896 KEEKK-ELEEESQKLNLLEEKENEIEERIKEEAEIL 930
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1855-2159 2.68e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 2.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1855 QKTLQEKELTCQALEQRVKELESDLVRErgahrlEVEKLTLKYEKSQSSQQEMdgENKCVEVLEDRPEENSQSHEIQSNV 1934
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEA------ELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1935 GTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQEldilkreceQEAEEKLKQEQEDLELKHTSTLKQLM 2014
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL---------EEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2015 REFNTQLAQKEQELERtvQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQ 2094
Cdd:COG1196    362 EAEEALLEAEAELAEA--EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992 2095 TQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2159
Cdd:COG1196    440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1535-2102 2.70e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 2.70e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1535 DLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHV 1614
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1615 SSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQryAKDTENRLS 1694
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA--AAELAAQLE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1695 ELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRR 1774
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1775 LEQGEGEARPSQPEAQHRALSGKLDCTRARQLED--HVLIGCLPEELEEKMKCSLIVSQPMGEETGNNtgvkqnwasVVD 1852
Cdd:COG1196    484 EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglRGLAGAVAVLIGVEAAYEAALEAALAAALQNI---------VVE 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1853 SVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQS 1932
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1933 NVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 2012
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2013 LMREFNTQLAQKEQELERTVQETIDKAQEVEAEL-------------LESHQEETQQLHRKIAEK-------EDDLRRTA 2072
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLeeealeelpeppdLEELERELERLEREIEALgpvnllaIEEYEELE 794

                          570       580       590
                   ....*....|....*....|....*....|
gi 1907198992 2073 RRYeeildareEEMTGKVTDLQTQLEELQK 2102
Cdd:COG1196    795 ERY--------DFLSEQREDLEEARETLEE 816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 189-898 2.74e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.23  E-value: 2.74e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  189 SREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSQdkslRRISELREELQMDQQAKKHLQDEF---D 265
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA----NEISRLEQQKQILRERLANLERQLeelE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  266 ACLEEKDQYISVLQTQVSLLKQRLQNGPMNVDapkplppgELQAEVhgDTEKMEGVGEPVGGGTSAKTLEMLQQRV---K 342
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELE--------SLEAEL--EELEAELEELESRLEELEEQLETLRSKVaqlE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  343 RQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQ 422
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEE 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  423 GEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQM--------------------KAVERASEEerlRLQH 482
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSglsgilgvlselisvdegyeAAIEAALGG---RLQA 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  483 ELSR----VRQEAASMAKKN---------SEEQVAALQKLHAEELASKEQELSRRLEARERELQ---------------E 534
Cdd:TIGR02168  550 VVVEnlnaAKKAIAFLKQNElgrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  535 QMRIALE---KSRSEYLKLTQEKEQQESL-ALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE--KSLQES 608
Cdd:TIGR02168  630 DLDNALElakKLRPGYRIVTLDGDLVRPGgVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAelRKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  609 KTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQslSQQHQAAVEELREKYQQEKDALLKEKESL 688
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE--LEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  689 fQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQ 768
Cdd:TIGR02168  788 -EAQIEQLKEE-LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  769 EltvrrAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQ 848
Cdd:TIGR02168  866 E-----LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907198992  849 MQQKVldleTEKSLLTKQvvEMETHKKHVCEELDAQRAQVQQLERQRSEL 898
Cdd:TIGR02168  941 LQERL----SEEYSLTLE--EAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1466-2157 6.65e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 6.65e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1466 KKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKM---EKKECDLETALKT 1542
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLanlERQLEELEAQLEE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1543 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHsglvQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELG 1622
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELE----AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1623 TVKKELEHVNSSVKSRDGELKALEDKLEL----ESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKdTENRLSELSA 1698
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEaelkELQAELEELEEELEELQEELERLEEALEELREELEE-AEQALDAAER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1699 QLKEREKQVHSLEDKLKNLE-------------SSPHPEVPAVSR------------------SMQSVAASPEQEAPDSQ 1747
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEgfsegvkallknqSGLSGILGVLSElisvdegyeaaieaalggRLQAVVVENLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1748 DCTHKACKERLCMLQRRLSEKEKL----LRRLEQGEGEARP-----SQPEAQHRALSGKLDCTR-----------ARQLE 1807
Cdd:TIGR02168  563 AFLKQNELGRVTFLPLDSIKGTEIqgndREILKNIEGFLGVakdlvKFDPKLRKALSYLLGGVLvvddldnalelAKKLR 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1808 DHVLIGCLPEEL---------EEKMKCSLIVSQpmGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESD 1878
Cdd:TIGR02168  643 PGYRIVTLDGDLvrpggvitgGSAKTNSSILER--RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1879 LVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLED-RPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK 1957
Cdd:TIGR02168  721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAeIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1958 LSKEVARLQKELRALRREHQQeldilkreceqeAEEKLKQEQEDLELKhtstlKQLMREFNTQLAQKEQELERTVQEtID 2037
Cdd:TIGR02168  801 LREALDELRAELTLLNEEAAN------------LRERLESLERRIAAT-----ERRLEDLEEQIEELSEDIESLAAE-IE 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2038 KAQEVEAELLESHQEETQQLhrkiaEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKds 2117
Cdd:TIGR02168  863 ELEELIEELESELEALLNER-----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE-- 935

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198992 2118 VTILELQTQLAQK--------TTLISDSKLKEQELREQVHNLEDRLKR 2157
Cdd:TIGR02168  936 VRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIKE 983
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 535-1221 6.75e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 64.86  E-value: 6.75e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  535 QMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKaiLTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEH 614
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFG--YKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNG 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  615 LAVHLEAEKNKHNKELTALAEQHR------TEVEGLQQQQDSLWTERLQSLSQQHqAAVEELREKYQQEKDALLKEKESL 688
Cdd:pfam12128  309 ELSAADAAVAKDRSELEALEDQHGafldadIETAAADQEQLPSWQSELENLEERL-KALTGKHQDVTAKYNRRRSKIKEQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  689 FQAHIQDMNEKTLEKLDKKQMELESVSSELsEALRA--RDQLAEELSVLRGDADKMKQAL------------EAELEEQR 754
Cdd:pfam12128  388 NNRDIAGIKDKLAKIREARDRQLAVAEDDL-QALESelREQLEAGKLEFNEEEYRLKSRLgelklrlnqataTPELLLQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  755 RHHQREVGSISEQQElTVRRAEKALKDELSRLGALLDERDEHLRERQARVQdleahlqksagELQQALAKLDLLHSEQSA 834
Cdd:pfam12128  467 ENFDERIERAREEQE-AANAEVERLQSELRQARKRRDQASEALRQASRRLE-----------ERQSALDELELQLFPQAG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  835 A-----REQAGAYEEQLAQMQQKVLDLETEkslLTKQVVEMETHKKHVCE--ELDAQRAQV-------QQLERQRSELEE 900
Cdd:pfam12128  535 TllhflRKEAPDWEQSIGKVISPELLHRTD---LDPEVWDGSVGGELNLYgvKLDLKRIDVpewaaseEELRERLDKAEE 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  901 KV---RSLAQLQDSQLKnstvekeQARQSLmekeniilqmrEEQAKEIEILKQTLSSKEESISILHEEYET-KFKNQEKR 976
Cdd:pfam12128  612 ALqsaREKQAAAEEQLV-------QANGEL-----------EKASREETFARTALKNARLDLRRLFDEKQSeKDKKNKAL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  977 MEKIKQKAKEMQ--ETKKKLLDQEAKL-KKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLT 1053
Cdd:pfam12128  674 AERKDSANERLNslEAQLKQLDKKHQAwLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALE 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1054 GAHQRKLD--DVIEAWEKKLSQQAAELRDKhAEQMEEKEQGLGELRQKVRivqsekEELTKEVARLKEAVSGQDVALAGL 1131
Cdd:pfam12128  754 TWYKRDLAslGVDPDVIAKLKREIRTLERK-IERIAVRRQEVLRYFDWYQ------ETWLQRRPRLATQLSNIERAISEL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1132 QGQLEQKSA-VIVSLSERESQLQSQvEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSeLTGQVQAAEKELQSCKS 1210
Cdd:pfam12128  827 QQQLARLIAdTKLRRAKLEMERKAS-EKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGS-IGERLAQLEDLKLKRDY 904

                          730
                   ....*....|.
gi 1907198992 1211 LHELSKKSLED 1221
Cdd:pfam12128  905 LSESVKKYVEH 915
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 364-1186 1.08e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.93  E-value: 1.08e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  364 LLLSEKEALQEQLDERLQELEKmkgmvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEK 443
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLAS-----LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEA 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  444 ALSTAQKTEDAQRRMKMEMDEQMKAVEraSEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSR 523
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEERLAKLE--AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  524 RLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEK 603
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  604 SLQE-SKTQSEHLAvhLEAEKNKHNKELTALAEQH----------RTEVEGLQQQQDSLWTER---------LQSLSQQH 663
Cdd:TIGR02169  460 LAADlSKYEQELYD--LKEEYDRVEKELSKLQRELaeaeaqarasEERVRGGRAVEEVLKASIqgvhgtvaqLGSVGERY 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  664 QAAVEEL-----------REKYQQEKDALLKEKEsLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEEL 732
Cdd:TIGR02169  538 ATAIEVAagnrlnnvvveDDAVAKEAIELLKRRK-AGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAF 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  733 SVLRGDA---DKMKQA-----------LEAELEEQ--------RRHHQREVGSISEQQEL-TVRRAEKALKDELSRLGAL 789
Cdd:TIGR02169  617 KYVFGDTlvvEDIEAArrlmgkyrmvtLEGELFEKsgamtggsRAPRGGILFSRSEPAELqRLRERLEGLKRELSSLQSE 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  790 LDERDEHLRERQARVQDLEAHLQKSAGELQQalakldlLHSEQSAAREQAGAYEEQLAQMQQKVLDLEtekslltkqvve 869
Cdd:TIGR02169  697 LRRIENRLDELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLSSLEQEIENVK------------ 757

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  870 methkkhvcEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNSTVEKEQArqslmekeniilqmrEEQAKEIEIL 948
Cdd:TIGR02169  758 ---------SELKELEARIEELEEDLHKLEEALNDLeARLSHSRIPEIQAELSKL---------------EEEVSRIEAR 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  949 KQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFnaqilemaq 1028
Cdd:TIGR02169  814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRL--------- 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1029 ansAGISDTVSRLEENQRQQiesltgahqrklddvieawEKKLSQQAAELrdkhaeqmEEKEQGLGELRQKVRIVQSEKE 1108
Cdd:TIGR02169  885 ---GDLKKERDELEAQLREL-------------------ERKIEELEAQI--------EKKRKRLSELKAKLEALEEELS 934

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992 1109 ELTKEVARLKEaVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADK 1186
Cdd:TIGR02169  935 EIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEE 1011
PTZ00121 PTZ00121
MAEBL; Provisional
 332-803 1.54e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.62  E-value: 1.54e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  332 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQ 411
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE 1422

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  412 LRSHIKQMTtQGEELREQKEKSERAafEELEKALSTAQKTEDAQRRMkmemDEQMKAVERASEEERLRLQHELSRVRQEA 491
Cdd:PTZ00121  1423 AKKKAEEKK-KADEAKKKAEEAKKA--DEAKKKAEEAKKAEEAKKKA----EEAKKADEAKKKAEEAKKADEAKKKAEEA 1495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  492 ---ASMAKKNSEEQVAALQKLHAEElASKEQELSRRLEARErelQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQ 568
Cdd:PTZ00121  1496 kkkADEAKKAAEAKKKADEAKKAEE-AKKADEAKKAEEAKK---ADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKK 1571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  569 KKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQ 648
Cdd:PTZ00121  1572 AEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE 1651

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  649 DSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQL 728
Cdd:PTZ00121  1652 LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIK 1731

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992  729 AEELSvlRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDElsrlgaLLDERDEHLRERQAR 803
Cdd:PTZ00121  1732 AEEAK--KEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE------ELDEEDEKRRMEVDK 1798
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 838-1720 3.96e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 62.37  E-value: 3.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  838 QAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRseleeKVRSLAQLQDSQLKNST 917
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSR-----EIVKSYENELDPLKNRL 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  918 VEKEQARQSLMEKENII-------LQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQET 990
Cdd:TIGR00606  255 KEIEHNLSKIMKLDNEIkalksrkKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  991 KKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVieaweKK 1070
Cdd:TIGR00606  335 RRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEA-----KT 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1071 LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSEres 1150
Cdd:TIGR00606  410 AAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERE--- 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1151 qlQSQVEKlEADLGCSLSEKLSLQEELAELklladksqlrvseltgqvqaaekELQSCKSLHELSKKSLEDKSLNLKSLL 1230
Cdd:TIGR00606  487 --LSKAEK-NSLTETLKKEVKSLQNEKADL-----------------------DRKLRKLDQEMEQLNHHTTTRTQMEML 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1231 EELASQLDSRCERTKAlleaktnelvctsrdKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKS 1310
Cdd:TIGR00606  541 TKDKMDKDEQIRKIKS---------------RHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQ 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1311 SFQQVTNQLEEKEKQIKTMKADI------EGLLTEKEALQQE---GGQQRQAASEKESCITQLKKELAENINAVTLLREE 1381
Cdd:TIGR00606  606 NKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEiekSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1382 LSEKKSEIASLSKQLSDLgaqlesSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNK 1461
Cdd:TIGR00606  686 VFQTEAELQEFISDLQSK------LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1462 FSEWKKKAQSRLAQHQSTIKDLQAQLDVKA--TDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLEta 1539
Cdd:TIGR00606  760 IQRLKNDIEEQETLLGTIMPEEESAKVCLTdvTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHE-- 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1540 LKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRlQHLEELGEEKDNKVREAEETVLRLREHVSSLEA 1619
Cdd:TIGR00606  838 LDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR-QQFEEQLVELSTEVQSLIREIKDAKEQDSPLET 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1620 elgTVKKELEHVNSSVKSRDGELKALEDKLElesaakvELKRKAEQKIAAiRKQLLSQMEEKTQRYAKDTENRLSELSAQ 1699
Cdd:TIGR00606  917 ---FLEKDQQEKEELISSKETSNKKAQDKVN-------DIKEKVKNIHGY-MKDIENKIQDGKDDYLKQKETELNTVNAQ 985

                          890       900
                   ....*....|....*....|.
gi 1907198992 1700 LKEREKQVHSLEDKLKNLESS 1720
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQD 1006
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 408-1003 4.52e-09

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 61.68  E-value: 4.52e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  408 EIAQLRSHIKQMTTQgeelREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRV 487
Cdd:pfam05557    3 ELIESKARLSQLQNE----KKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELN 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  488 RQEAASMAKKNSEEQVAALQKLHAEELAS-KEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELE 566
Cdd:pfam05557   79 RLKKKYLEALNKKLNEKESQLADAREVIScLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNL 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  567 LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHleaEKNKHNKELTALAEQHRTEVEGLQQ 646
Cdd:pfam05557  159 EKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELERLR---EHNKHLNENIENKLLLKEEVEDLKR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  647 QQDSlwterlQSLSQQHQAAVEELREKYQQEkdalLKEKESLFQAHIQDMNE--------KTLEKLDKKQME-LESVSSE 717
Cdd:pfam05557  236 KLER------EEKYREEAATLELEKEKLEQE----LQSWVKLAQDTGLNLRSpedlsrriEQLQQREIVLKEeNSSLTSS 305

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  718 LSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQELtVRRAEKALKDELSrlgalldeRDEHL 797
Cdd:pfam05557  306 ARQLEKARRELEQELAQYLKKIEDLNKKLK-RHKALVRRLQRRVLLLTKERDG-YRAILESYDKELT--------MSNYS 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  798 RERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVldlETEKSLLTKQVVEmethkkHV 877
Cdd:pfam05557  376 PQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQE---SLADPSYSKEEVD------SL 446

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  878 CEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVekeqarqsLMEKENIILQMREEQAKEIEILKQTLSSKEE 957
Cdd:pfam05557  447 RRKLETLELERQRLREQKNELEMELERRCLQGDYDPKKTKV--------LHLSMNPAAEAYQQRKNQLEKLQAEIERLKR 518

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1907198992  958 SISILHEEYETKfknQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 1003
Cdd:pfam05557  519 LLKKLEDDLEQV---LRLPETTSTMNFKEVLDLRKELESAELKNQR 561
PTZ00121 PTZ00121
MAEBL; Provisional
 1445-2161 5.29e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 5.29e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1445 SKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEME 1523
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1524 VRKSKMEKKEcdlETALKTQTAR-VVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVRE 1602
Cdd:PTZ00121  1163 ARKAEEARKA---EDAKKAEAARkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1603 AE----ETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQkiaAIRKQLLSQM 1678
Cdd:PTZ00121  1240 EEakkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE---AKKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1679 EEKTQRYAKDTENRLSELSAQLKEREKQvhslEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERL 1758
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1759 CMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETG 1838
Cdd:PTZ00121  1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1839 NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1918
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1919 dRPEENSQSHEIQSnvgtVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-EKLKQ 1997
Cdd:PTZ00121  1553 -KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1998 EQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE---AELLESHQEETQQLHRKIAEKEDDLRRTA-- 2072
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEel 1707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2073 -------RRYEEILDAREEEMTGKVTDLQTQLEElQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELR 2145
Cdd:PTZ00121  1708 kkkeaeeKKKAEELKKAEEENKIKAEEAKKEAEE-DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                          730
                   ....*....|....*.
gi 1907198992 2146 EQVHNLEDRLKRYEKN 2161
Cdd:PTZ00121  1787 EEDEKRRMEVDKKIKD 1802
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1293-2108 5.58e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 5.58e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1293 ELEAQLTQLteEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENI 1372
Cdd:TIGR02168  217 ELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1373 NAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSAL 1452
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1453 EQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQL-DVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEK 1531
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLeRLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1532 KECDLETALKTQTARVVELEDCVTQRKKEVESLN---ETLKNYNQQRDTEHSGLVQRLQHLEELGE---------EKDNK 1599
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEGVKALLKNQSGLSGilgvlseliSVDEG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1600 VREAEETVlrLREHVSSLEAElgTVKKELEHVNSSVKSRDGELKALEdkLELESAAKVELKRKAEQKIAAIRKQLLSQME 1679
Cdd:TIGR02168  535 YEAAIEAA--LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVTFLP--LDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1680 EKTQRYAKDTENRLS------------ELSAQLKEREKQVhSLEDKLknleSSPHPEVPAVSRSMQSVAASPEQEAPDSQ 1747
Cdd:TIGR02168  609 KFDPKLRKALSYLLGgvlvvddldnalELAKKLRPGYRIV-TLDGDL----VRPGGVITGGSAKTNSSILERRREIEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1748 DCThKACKERLCMLQRRLSEKEKLLRRLEQGEGEAR--PSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKC 1825
Cdd:TIGR02168  684 EKI-EELEEKIAELEKALAELRKELEELEEELEQLRkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1826 SLIVSQPMGEETGNNTGVKQNWASVVDSVQKtlqekeltcqaLEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQ 1905
Cdd:TIGR02168  763 IEELEERLEEAEEELAEAEAEIEELEAQIEQ-----------LKEELKALREALDELRAELTLLNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1906 EMDGENKCVEVLEDRPEENSQSHE-IQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALR---REHQQELD 1981
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIEsLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSeelRELESKRS 911

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1982 ILKRECE--QEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLaqkeQELERTVQETIDKAQEVEAElLESHQEETQQLHR 2059
Cdd:TIGR02168  912 ELRRELEelREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL----EEAEALENKIEDDEEEARRR-LKRLENKIKELGP 986

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1907198992 2060 KIAEKEDDLRRTARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRL 2108
Cdd:TIGR02168  987 VNLAAIEEYEELKERYDF-LTAQKEDLTEAKETLEEAIEEIDREARERF 1034
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 542-1008 6.03e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.57  E-value: 6.03e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  542 KSRSEYLKLTQEKEQQESLALEELE--LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQE-SKTQSEHLAVH 618
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTeiKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNiDKIKNKLLKLE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  619 LE----AEKNKHNKELTA----LAEQHRTEVEGLQQQQDSL---------WTERLQSLSQQHQAAVEELREKYQQ--EKD 679
Cdd:TIGR04523  201 LLlsnlKKKIQKNKSLESqiseLKKQNNQLKDNIEKKQQEInektteisnTQTQLNQLKDEQNKIKKQLSEKQKEleQNN 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  680 ALLKEKESLFQA-----------HIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKmKQALEA 748
Cdd:TIGR04523  281 KKIKELEKQLNQlkseisdlnnqKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTN-SESENS 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  749 ELEEQRRHHQREVGSISEQQELTVRRAEKaLKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLL 828
Cdd:TIGR04523  360 EKQRELEEKQNEIEKLKKENQSYKQEIKN-LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  829 HSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQL 908
Cdd:TIGR04523  439 NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  909 QDSQLKNS---TVEKEQARQSLMEKENIILQMREEQAKEIeiLKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAK 985
Cdd:TIGR04523  519 ISSLKEKIeklESEKKEKESKISDLEDELNKDDFELKKEN--LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEK 596

                          490       500
                   ....*....|....*....|....*.
gi 1907198992  986 EMQETKKKLLDQEAK---LKKELENT 1008
Cdd:TIGR04523  597 EKKDLIKEIEEKEKKissLEKELEKA 622
PTZ00121 PTZ00121
MAEBL; Provisional
 1459-2119 6.64e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 6.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1459 SNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKME----KKE 1533
Cdd:PTZ00121  1169 ARKAEDAKKAEAARKAEEVRKAEELRKAEDArKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEakkaEEE 1248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1534 CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGE--EKDNKVREAEETVLRLR 1611
Cdd:PTZ00121  1249 RNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAK 1328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1612 EHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEqkiAAIRKQLLSQMEEKTQRYAKDTEN 1691
Cdd:PTZ00121  1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD---AAKKKAEEKKKADEAKKKAEEDKK 1405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1692 RLSELSAQlKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKL 1771
Cdd:PTZ00121  1406 KADELKKA-AAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK 1484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1772 LRRLEQGEGEARPSQPEAQHRAlSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVV 1851
Cdd:PTZ00121  1485 ADEAKKKAEEAKKKADEAKKAA-EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEK 1563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1852 DSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQ 1931
Cdd:PTZ00121  1564 KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1932 SNVGTVDGLRSDLESKLTGAERDKQKlSKEVARLQKELRALRREHQQELDILKRECEQ--EAEEKLKQEQEDLELKHTST 2009
Cdd:PTZ00121  1644 EEKKKAEELKKAEEENKIKAAEEAKK-AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEakKAEELKKKEAEEKKKAEELK 1722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2010 LKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGK 2089
Cdd:PTZ00121  1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802

                          650       660       670
                   ....*....|....*....|....*....|
gi 1907198992 2090 VTDLQTQLEELQKKYQQRLEQEESTKDSVT 2119
Cdd:PTZ00121  1803 IFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 967-1570 8.25e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.80  E-value: 8.25e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  967 ETKFKNQEKRMEKI----KQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEKQFNAQILEMAQANSAGISD-TVSRL 1041
Cdd:TIGR04523   32 DTEEKQLEKKLKTIknelKNKEKELKNLDKNLNKDEEK-INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDlSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1042 EENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAV 1121
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKE-LEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1122 SGQDVALAglqgQLEQKSAVIVSLSERESQLQSQVEKLEadlgcslseklslqEELAELKLLADKSQLRVSELTGQVQAA 1201
Cdd:TIGR04523  190 DKIKNKLL----KLELLLSNLKKKIQKNKSLESQISELK--------------KQNNQLKDNIEKKQQEINEKTTEISNT 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1202 EKELQSCKSLHELSKKSLEDKSLNL---KSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTA 1278
Cdd:TIGR04523  252 QTQLNQLKDEQNKIKKQLSEKQKELeqnNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQIS 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1279 TVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKE 1358
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKD 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1359 SCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLES-SISPSDKAEAISALSKQHEEQELQLQAQLQEL 1437
Cdd:TIGR04523  412 EQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNlDNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1438 SLKV---DALSKEKMSALEQVDHWSNKFSEWKKKAQ---SRLAQHQSTIKDLQAQLDVKATDAREKeeqicLLKEDLDRQ 1511
Cdd:TIGR04523  492 KSKEkelKKLNEEKKELEEKVKDLTKKISSLKEKIEkleSEKKEKESKISDLEDELNKDDFELKKE-----NLEKEIDEK 566

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198992 1512 NKKFECLKGEMEVRKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKN 1570
Cdd:TIGR04523  567 NKEIEELKQTQKSLKKKQEEKQelidqkekekKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 377-1227 1.05e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 60.76  E-value: 1.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  377 DERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKqmttqGEELREQKEKSERAAFEELEKALSTAQKTEDAQR 456
Cdd:pfam02463  153 ERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLE-----ELKLQELKLKEQAKKALEYYQLKEKLELEEEYLL 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  457 RMKMEMDEQmKAVERASEEERLRLQHELS--RVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQE 534
Cdd:pfam02463  228 YLDYLKLNE-ERIDLLQELLRDEQEEIESskQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLE 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  535 QMRIALEKSRSEyLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEH 614
Cdd:pfam02463  307 RRKVDDEEKLKE-SEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  615 LAvhLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQqhQAAVEELREKYQQEKDALLKEKESLfQAHIQ 694
Cdd:pfam02463  386 LS--SAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELE--ILEEEEESIELKQGKLTEEKEELEK-QELKL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  695 DMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRR 774
Cdd:pfam02463  461 LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  775 AEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQaLAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVL 854
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPK-LKLPLKSIAVLEIDPILNLAQLDKATLEADEDD 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  855 DLETEKSLLTKQVVEMETHKKHVCEELDAQRAQvqqlERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENII 934
Cdd:pfam02463  620 KRAKVVEGILKDTELTKLKESAKAKESGLRKGV----SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEIL 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  935 LQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ 1014
Cdd:pfam02463  696 RRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1015 KEKQFNAQILEMAQ--------ANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQM 1086
Cdd:pfam02463  776 LAEEREKTEKLKVEeekeeklkAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1087 EEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCS 1166
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE 935

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198992 1167 LSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLK 1227
Cdd:pfam02463  936 EPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELE 996
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1554-2159 1.05e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 1.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1554 VTQRKKEVESLNETLKNYNQQRDTehsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNS 1633
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEE----LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1634 SVKSRDGELKALEDKLELESAAKVELKRKAEQ--------------------KIAAIRKQLLSQMEEKTQRY------AK 1687
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAEleekleelkeelesleaeleELEAELEELESRLEELEEQLetlrskVA 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1688 DTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSE 1767
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1768 KEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV------------LIGCLPEELE--------------- 1820
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkallknqsglsgILGVLSELISvdegyeaaieaalgg 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1821 -----------------------EKMKCSLIV--------SQPMGEETGNNTGVKQNWASVVDSVQKTLQE--------- 1860
Cdd:TIGR02168  546 rlqavvvenlnaakkaiaflkqnELGRVTFLPldsikgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggv 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1861 ---KELTcQALEQRVKE--------LESDLVRERGAHRLEVEKLTLkyeKSQSSQQEMDGENKCVEVLEdrpeenSQSHE 1929
Cdd:TIGR02168  626 lvvDDLD-NALELAKKLrpgyrivtLDGDLVRPGGVITGGSAKTNS---SILERRREIEELEEKIEELE------EKIAE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1930 IQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTST 2009
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2010 LKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAEL------LESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDARE 2083
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELtllneeAANLRERLESLERRIAATERRLEDLEEQIEE-LSEDI 854

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198992 2084 EEMTGKVTDLQTQLEELQKKYQQRLEQEESTKdsVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2159
Cdd:TIGR02168  855 ESLAAEIEELEELIEELESELEALLNERASLE--EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1290-1720 1.23e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.42  E-value: 1.23e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1290 QVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELA 1369
Cdd:TIGR04523  219 QISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1370 ENINAVTllREELSEKKSEIASLSKQLSDLGAQLESSISP-SDKAEAISALSKQHEEQELQLQAQLQELSLKVDA---LS 1445
Cdd:TIGR04523  299 DLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIiSQLNEQISQLKKELTNSESENSEKQRELEEKQNEiekLK 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1446 KEKMSALEQVDHWSNKFSEWKKKAQsrlaQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVR 1525
Cdd:TIGR04523  377 KENQSYKQEIKNLESQINDLESKIQ----NQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1526 K---SKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKVRE 1602
Cdd:TIGR04523  453 EliiKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEK 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1603 AEETVLRLREHVSSLEAELGTVKKEL--EHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKiAAIRKQLLSQMEE 1680
Cdd:TIGR04523  529 LESEKKEKESKISDLEDELNKDDFELkkENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQK-EKEKKDLIKEIEE 607

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1907198992 1681 KTQryakdtenRLSELSAQLKEREKQVHSLEDKLKNLESS 1720
Cdd:TIGR04523  608 KEK--------KISSLEKELEKAKKENEKLSSIIKNIKSK 639
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1290-1718 1.35e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1290 QVSELEAQLTQLTEEQRTLKSSFQQVTNQL---EEKEKQIKTMKADIEGL-------LTEKEALQQEGGQQRQAASEKES 1359
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLretiaetEREREELAEEVRDLRERLEELEE 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1360 CITQLKKELA---ENINAVTLLREELSEKKSEIA-SLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQ 1435
Cdd:PRK02224   294 ERDDLLAEAGlddADAEAVEARREELEDRDEELRdRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1436 ELSLKVDAlSKEKMSALE-QVDHWSNKFS---EWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLlKEDLDRQ 1511
Cdd:PRK02224   374 EAREAVED-RREEIEELEeEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1512 NKKFECLK-----------GEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQrKKEVESLNETLKNYNQQRDTEHS 1580
Cdd:PRK02224   452 GKCPECGQpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1581 GLVQRLQHLEEL----------GEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNsSVKSRDGELKALEDKLE 1650
Cdd:PRK02224   531 TIEEKRERAEELreraaeleaeAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIE 609

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992 1651 LESAAKVELKRKAEQKiaaiRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1718
Cdd:PRK02224   610 RLREKREALAELNDER----RERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
998-1402 1.50e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  998 EAKLKKELENTVLELSQKEKQFNAQIlemaqansagisdtvSRLEENQRQQIESLTgahqrKLDDVIEAWEKKLsqqaae 1077
Cdd:PRK02224   197 EEKEEKDLHERLNGLESELAELDEEI---------------ERYEEQREQARETRD-----EADEVLEEHEERR------ 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1078 lrdkhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1157
Cdd:PRK02224   251 ------EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1158 KLEADL-------GCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSL------ 1224
Cdd:PRK02224   325 ELRDRLeecrvaaQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdap 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1225 ----NLKSLLEELASQLD-----------------SRCERTKALLEA----------KTNELVCT---SRDKADAILARL 1270
Cdd:PRK02224   405 vdlgNAEDFLEELREERDelrereaeleatlrtarERVEEAEALLEAgkcpecgqpvEGSPHVETieeDRERVEELEAEL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1271 SQCQRHTATVgEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ 1350
Cdd:PRK02224   485 EDLEEEVEEV-EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992 1351 RQAASEKESCITQLKKELAENINAVTLLR------EELSEKKSEIASLSKQLSDLGAQ 1402
Cdd:PRK02224   564 EEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAEL 621
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
483-1008 1.68e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.31  E-value: 1.68e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  483 ELSRVRQEAASMakknsEEQVAALQKLhaEELASKEQELSRRLEARERELQeqmrialeksrseylKLTQEKEQQESLAL 562
Cdd:COG4913    236 DLERAHEALEDA-----REQIELLEPI--RELAERYAAARERLAELEYLRA---------------ALRLWFAQRRLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  563 EELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVE 642
Cdd:COG4913    294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGL 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  643 GLQQQQDSLWteRLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHiqdmnektlEKLDKKQMELESVSSEL-SEA 721
Cdd:COG4913    374 PLPASAEEFA--ALRAEAAALLEALEEELEALEEALAEAEAALRDLRREL---------RELEAEIASLERRKSNIpARL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  722 LRARDQLAEELSV-------------LRGDADKMKQALEAELEEQRR------HHQREVGSISEQQELTVR-RAEKALKD 781
Cdd:COG4913    443 LALRDALAEALGLdeaelpfvgelieVRPEEERWRGAIERVLGGFALtllvppEHYAAALRWVNRLHLRGRlVYERVRTG 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  782 ELSRLGALLDER-----------------DEHLRERQARV-----QDLEAH--------LQKSAGEL------------- 818
Cdd:COG4913    523 LPDPERPRLDPDslagkldfkphpfrawlEAELGRRFDYVcvdspEELRRHpraitragQVKGNGTRhekddrrrirsry 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  819 ---QQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLtkqvvemETHKKHVCEELDAQ--RAQVQQLER 893
Cdd:COG4913    603 vlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-------QRLAEYSWDEIDVAsaEREIAELEA 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  894 QRSELEEKVRSLAQLQD--SQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISI-LHEEYETKF 970
Cdd:COG4913    676 ELERLDASSDDLAALEEqlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERF 755

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1907198992  971 KNQEKRmEKIKQKAKEMQETKKKLLDQEAKLKKELENT 1008
Cdd:COG4913    756 AAALGD-AVERELRENLEERIDALRARLNRAEEELERA 792
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1555-2110 2.59e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1555 TQRKKEVESLNETLKNYNQQRDTEHsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEA--------ELGTVKK 1626
Cdd:COG4913    268 RERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELERLEARLDALREELDELEAqirgnggdRLEQLER 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1627 ELEHVNSSVKSRDGELKALEDKLelesaAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQ 1706
Cdd:COG4913    346 EIERLERELEERERRRARLEALL-----AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1707 VHSLEDKLKNLESSP---HPEVPAVSRSMQSVAASPEQEAP--------DSQDCTHKACKER------LCML--QRRLS- 1766
Cdd:COG4913    421 LRELEAEIASLERRKsniPARLLALRDALAEALGLDEAELPfvgelievRPEEERWRGAIERvlggfaLTLLvpPEHYAa 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1767 -----EKEKLLRRL---EQGEGEARPSQPEAQHRALSGKLD----------------------CTRARQLEDH---VLIG 1813
Cdd:COG4913    501 alrwvNRLHLRGRLvyeRVRTGLPDPERPRLDPDSLAGKLDfkphpfrawleaelgrrfdyvcVDSPEELRRHpraITRA 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1814 CL---PEELEEKmkcslivsqpmgeetGNNTGVKQNWASVVDSVQKtLQEKELTCQALEQRVKELESDLVRERGAHRLEV 1890
Cdd:COG4913    581 GQvkgNGTRHEK---------------DDRRRIRSRYVLGFDNRAK-LAALEAELAELEEELAEAEERLEALEAELDALQ 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1891 EKLTL--KYEKSQSSQQEMDGENKCVEVLEDRPEE----NSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVAR 1964
Cdd:COG4913    645 ERREAlqRLAEYSWDEIDVASAEREIAELEAELERldasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQ 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1965 LQKELRALRREHQQELDILKRECEQEAEEKLKQE-QEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE 2043
Cdd:COG4913    725 AEEELDELQDRLEAAEDLARLELRALLEERFAAAlGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAET 804

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198992 2044 AELLES--HQEETQQLHRKIaeKEDDLrrtARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQ 2110
Cdd:COG4913    805 ADLDADleSLPEYLALLDRL--EEDGL---PEYEERFKELLNENSIEFVADLLSKLRRAIREIKERIDP 868
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2187-2230 3.62e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.45  E-value: 3.62e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907198992  2187 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2230
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 628-1011 4.43e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 4.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  628 KELTALAEQHRTEVEGLQQQQDSLWTE--RLQSLSQQHQAAVEELrekyQQEKDALLKEKESLFQAHiqdmnEKTLEKLD 705
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSElrRIENRLDELSQELSDA----SRKIGEIEKEIEQLEQEE-----EKLKERLE 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  706 KKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSR 785
Cdd:TIGR02169  741 ELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQK 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  786 LGALLDERDEHLRERQARVQDL-EAHLQKSAGELQQALAKLDLlhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLLT 864
Cdd:TIGR02169  821 LNRLTLEKEYLEKEIQELQEQRiDLKEQIKSIEKEIENLNGKK------------EELEEELEELEAALRDLESRLGDLK 888

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  865 KQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQlqdsqlKNSTVEKEQARQSLMEKENIILQMREEQAKE 944
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE------ELSEIEDPKGEDEEIPEEELSLEDVQAELQR 962

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907198992  945 IEILKQTLsskeESISILHEEyetKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLE 1011
Cdd:TIGR02169  963 VEEEIRAL----EPVNMLAIQ---EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 858-1673 5.65e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 5.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  858 TEKSLLTKQVVEMETHKKHVceeldaQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQM 937
Cdd:pfam15921   49 TQIPIFPKYEVELDSPRKII------AYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  938 REEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLkKELENTVLELSQKEK 1017
Cdd:pfam15921  123 QMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVL-QEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1018 QFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGaHQRKLDDVIEAWEKKLSQQAAELRDKHAEQME----EKEQGL 1093
Cdd:pfam15921  202 KKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG-RIFPVEDQLEALKSESQNKIELLLQQHQDRIEqlisEHEVEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1094 GELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVS-LSERESQLQSQVEKLEADLGCSLSEKLS 1172
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSeLREAKRMYEDKIEELEKQLVLANSELTE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1173 LQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckSLHELSKKSLEDKSLNLKSLLEELASQLDSR---CERTKALLE 1249
Cdd:pfam15921  361 ARTERDQFSQESGNLDDQLQKLLADLHKREKEL----SLEKEQNKRLWDRDTGNSITIDHLRRELDDRnmeVQRLEALLK 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1250 AKTNELVCTSRDKADAILARLSQCQRHTATVGE-----ALLRRMgqVSELEAQLTQLTEEQRT---LKSSFQQVTNQLEE 1321
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQlestkEMLRKV--VEELTAKKMTLESSERTvsdLTASLQEKERAIEA 514

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1322 KEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitqLKKELAENINAVTLLREELSEKKSEIASLSKQLSDL-- 1399
Cdd:pfam15921  515 TNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEA----LKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqv 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1400 -GAQLESSISpsdkaeaisalskqheeqelqlqaQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQS 1478
Cdd:pfam15921  591 eKAQLEKEIN------------------------DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR 646

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1479 TIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1558
Cdd:pfam15921  647 AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM 726

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1559 KEVESLNETLKNYNQQRDtehsGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSS---V 1635
Cdd:pfam15921  727 KVAMGMQKQITAKRGQID----ALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQerrL 802

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1907198992 1636 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQ 1673
Cdd:pfam15921  803 KEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQ 840
PTZ00121 PTZ00121
MAEBL; Provisional
 1000-1718 6.37e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 6.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1000 KLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELR 1079
Cdd:PTZ00121  1028 KIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTE 1107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1080 DKHAEQMEEKEQGLGELRQKVRIVQSEKEEltkEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSlseRESQLQSQVEKL 1159
Cdd:PTZ00121  1108 TGKAEEARKAEEAKKKAEDARKAEEARKAE---DARKAEEARKAEDAKRVEIARKAEDARKAEEA---RKAEDAKKAEAA 1181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1160 EADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAE-----KELQSCKSLHELSKKSLEDKSLNLKSLLEELA 1234
Cdd:PTZ00121  1182 RKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKkaeavKKAEEAKKDAEEAKKAEEERNNEEIRKFEEAR 1261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1235 SQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTatvgeallRRMGQVSELEAQLTQLTEEQRTLKSSFQQ 1314
Cdd:PTZ00121  1262 MAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA--------DEAKKKAEEAKKADEAKKKAEEAKKKADA 1333

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1315 VTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAvtllrEELSEKKSEIASLSK 1394
Cdd:PTZ00121  1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA-----DEAKKKAEEDKKKAD 1408

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1395 QLSDLGAQLESSISPSDKAEAIsalsKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSrlA 1474
Cdd:PTZ00121  1409 ELKKAAAAKKKADEAKKKAEEK----KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE--A 1482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1475 QHQSTIKDLQAQLDVKATDAREKEEQicllKEDLDRQNKKFECLKGEmEVRKSKMEKKECDLETA---------LKTQTA 1545
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADEAKKAAEA----KKKADEAKKAEEAKKAD-EAKKAEEAKKADEAKKAeekkkadelKKAEEL 1557

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1546 RVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEaelgtVK 1625
Cdd:PTZ00121  1558 KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE-----EK 1632

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1626 KELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREK 1705
Cdd:PTZ00121  1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEA 1712

                          730
                   ....*....|...
gi 1907198992 1706 QVHSLEDKLKNLE 1718
Cdd:PTZ00121  1713 EEKKKAEELKKAE 1725
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 367-1026 6.82e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 6.82e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  367 SEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALS 446
Cdd:pfam02463  271 LKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIK 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  447 TAQKTEDAQRRMKmEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELAS-----KEQEL 521
Cdd:pfam02463  351 REAEEEEEEELEK-LQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDllkeeKKEEL 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  522 SRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSL 601
Cdd:pfam02463  430 EILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGL 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  602 EKSLQESKTQ-----------SEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEEL 670
Cdd:pfam02463  510 KVLLALIKDGvggriisahgrLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKL 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  671 REK-YQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAE 749
Cdd:pfam02463  590 PLKsIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLS 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  750 LEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLH 829
Cdd:pfam02463  670 ELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEE 749

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  830 SEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQvqqlERQRSELEEKVRSLAQLQ 909
Cdd:pfam02463  750 EEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE----EELKEEAELLEEEQLLIE 825

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  910 DSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEkiKQKAKEMQE 989
Cdd:pfam02463  826 QEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEK--EKEEKKELE 903

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1907198992  990 TKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEM 1026
Cdd:pfam02463  904 EESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL 940
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 406-755 1.17e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  406 EDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASE-EERLR-LQHE 483
Cdd:TIGR02169  673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEElEEDLSsLEQE 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  484 LSRVRQEAASMAKKNSEEQV------AALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEylkltqEKEQQ 557
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEdlhkleEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKL------NRLTL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  558 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEqh 637
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG-DLKKERDELEAQLRELER-- 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  638 rteveglQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVS-- 715
Cdd:TIGR02169  904 -------KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNml 976

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1907198992  716 --SELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRR 755
Cdd:TIGR02169  977 aiQEYEEVLKRLDELKEKRAKLEEERKAILERIE-EYEKKKR 1017
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 360-1028 1.32e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 57.29  E-value: 1.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  360 EQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAafE 439
Cdd:TIGR00618  179 TQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQ--L 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  440 ELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERL------------RLQHELSRVRQEAASMAKKNSEEQVAALQ 507
Cdd:TIGR00618  257 KKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLaahikavtqieqQAQRIHTELQSKMRSRAKLLMKRAAHVKQ 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  508 KLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLK---LTQEKEQQESLALEELELQKKAILTESENKLQELG 584
Cdd:TIGR00618  337 QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTqhiHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRT 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  585 QEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKhNKELTALAEQHRTEVEGLQQQQDSLwterlqsLSQQHQ 664
Cdd:TIGR00618  417 SAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLE-KIHLQESAQSLKEREQQLQTKEQIH-------LQETRK 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  665 AAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEAlRARDQLAEELSVLRGDADKMKQ 744
Cdd:TIGR00618  489 KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE-DVYHQLTSERKQRASLKEQMQE 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  745 ALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAK 824
Cdd:TIGR00618  568 IQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTA 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  825 L-----DLLHSEQSAAREQAGAYEEQLAQMQQKVLD---------------LETEKSLLTKQVVEMETHKKHVCEELDAQ 884
Cdd:TIGR00618  648 LhalqlTLTQERVREHALSIRVLPKELLASRQLALQkmqsekeqltywkemLAQCQTLLRELETHIEEYDREFNEIENAS 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  885 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEESISILHE 964
Cdd:TIGR00618  728 SSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQ-TGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198992  965 EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQ 1028
Cdd:TIGR00618  807 EIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAK 870
mukB PRK04863
chromosome partition protein MukB;
536-907 1.69e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 56.89  E-value: 1.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  536 MRIALEKSRSEYLKLTQEKEQQeslaleelelQKKAILTESENKLQELGQEAEAyrtrILELETSLEkslQESKTQSEHL 615
Cdd:PRK04863   275 MRHANERRVHLEEALELRRELY----------TSRRQLAAEQYRLVEMARELAE----LNEAESDLE---QDYQAASDHL 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  616 AVHLEAEK--NKHNK------ELTALAEQHRTEVEGLQQQQDSLWTE---------RLQSLSQQHQAAVEELREK---YQ 675
Cdd:PRK04863   338 NLVQTALRqqEKIERyqadleELEERLEEQNEVVEEADEQQEENEARaeaaeeevdELKSQLADYQQALDVQQTRaiqYQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  676 QEKDALLKEKE-----SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVL--------RGDADKM 742
Cdd:PRK04863   418 QAVQALERAKQlcglpDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVrkiagevsRSEAWDV 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  743 KQALEAELEEQRRHHQREVGSISEQQELTVR-----RAEKALKDELSRLGALLDERDE---HLRERQARVQDLE---AHL 811
Cdd:PRK04863   498 ARELLRRLREQRHLAEQLQQLRMRLSELEQRlrqqqRAERLLAEFCKRLGKNLDDEDEleqLQEELEARLESLSesvSEA 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  812 QKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDletekSLLTKQvvEMETHKKHVCEELDAQRAQVQQL 891
Cdd:PRK04863   578 RERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGE-----EFEDSQ--DVTEYMQQLLERERELTVERDEL 650

                          410
                   ....*....|....*.
gi 1907198992  892 ERQRSELEEKVRSLAQ 907
Cdd:PRK04863   651 AARKQALDEEIERLSQ 666
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1573-2157 1.80e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.80e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1573 QQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLE-L 1651
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1652 ESAAKVELKRKAEqkIAAIRKQLLSQMEEKTQRYAKDTEnRLSELSAQLKEREKQVHSLEDKLKNLESSphpevpavsRS 1731
Cdd:COG1196    301 EQDIARLEERRRE--LEERLEELEEELAELEEELEELEE-ELEELEEELEEAEEELEEAEAELAEAEEA---------LL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1732 MQSVAASPEQEApdsqdctHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARpsqpEAQHRALSGKLDCTRARQLEDHVL 1811
Cdd:COG1196    369 EAEAELAEAEEE-------LEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEELEELEEALAELEEEE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1812 IGCLPEELEEKmkcslivsqpmGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVE 1891
Cdd:COG1196    438 EEEEEALEEAA-----------EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1892 KLTLKYEKSQSSQQEMDGEnkcVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK-------LSKEVAR 1964
Cdd:COG1196    507 LEGVKAALLLAGLRGLAGA---VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratfLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1965 LQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEA 2044
Cdd:COG1196    584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2045 ELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSVTILELQ 2124
Cdd:COG1196    664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1907198992 2125 TQLAQKTTLISD--SKLKEQELREQVHNLEDRLKR 2157
Cdd:COG1196    744 EEELLEEEALEElpEPPDLEELERELERLEREIEA 778
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
395-930 2.64e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.08  E-value: 2.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  395 KRQMLETLELKEDeIAQLRSHIKQ---MTTQGEELREQKEKSE--RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV 469
Cdd:COG4913    214 REYMLEEPDTFEA-ADALVEHFDDlerAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLEL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  470 ERAsEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALE-KSRSEYL 548
Cdd:COG4913    293 LEA-ELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARlEALLAAL 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  549 KLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKnkhnK 628
Cdd:COG4913    372 GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALR----D 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  629 ELTALAEQHRTEV----EGLQ-QQQDSLWT---ERL---QSLS----QQHQAAVeelREKYQQEKDAL----LKEKESLF 689
Cdd:COG4913    448 ALAEALGLDEAELpfvgELIEvRPEEERWRgaiERVlggFALTllvpPEHYAAA---LRWVNRLHLRGrlvyERVRTGLP 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  690 QAHIQDMNEKTL-EKLDKK--------QMELESVSS--------ELSEALRA------------------RDQLAEELsV 734
Cdd:COG4913    525 DPERPRLDPDSLaGKLDFKphpfrawlEAELGRRFDyvcvdspeELRRHPRAitragqvkgngtrhekddRRRIRSRY-V 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  735 LRGDADKMKQALEAELEEQRRHHQRevgsiSEQQELTVRRAEKALKDELSRLGALLDerdehLRERQARVQDLEAHLQks 814
Cdd:COG4913    604 LGFDNRAKLAALEAELAELEEELAE-----AEERLEALEAELDALQERREALQRLAE-----YSWDEIDVASAEREIA-- 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  815 agELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDA-----QRAQVQ 889
Cdd:COG4913    672 --ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaedlaRLELRA 749

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907198992  890 QLERQRSEL--EEKVRSLAQLQDSQLKNSTVEKEQARQSLMEK 930
Cdd:COG4913    750 LLEERFAAAlgDAVERELRENLEERIDALRARLNRAEEELERA 792
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 488-1099 2.69e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 56.39  E-value: 2.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  488 RQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEA-----RERELQEQMRIALEKSRSEYLKLTQEKEQQESLAL 562
Cdd:pfam12128  277 RQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvakdrSELEALEDQHGAFLDADIETAAADQEQLPSWQSEL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  563 EELELQKKAiLTESENKLQElgqeaeAYRTRILELetslekslqesktqSEHLAVHLEAEKNKHNKELTALAEQHrTEVE 642
Cdd:pfam12128  357 ENLEERLKA-LTGKHQDVTA------KYNRRRSKI--------------KEQNNRDIAGIKDKLAKIREARDRQL-AVAE 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  643 GLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEK----DALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSEL 718
Cdd:pfam12128  415 DDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKlrlnQATATPELLLQLENFDERIERAREEQEAANAEVERLQSEL 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  719 SEALRARDQLAEELSVLRGDADKMKQALEaELEEQ------RRHH--QREVGSISEQQELTVRRA------------EKA 778
Cdd:pfam12128  495 RQARKRRDQASEALRQASRRLEERQSALD-ELELQlfpqagTLLHflRKEAPDWEQSIGKVISPEllhrtdldpevwDGS 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  779 LKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAReqaGAYEEQLAQMQQKVLDLET 858
Cdd:pfam12128  574 VGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQAN---GELEKASREETFARTALKN 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  859 EKSLLTKQVVEMETHKKHVCEELDAQRA----QVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLM-EKENI 933
Cdd:pfam12128  651 ARLDLRRLFDEKQSEKDKKNKALAERKDsaneRLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEgALDAQ 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  934 ILQMREEQAKEIEILKQTLSS--------------KEESISILH---EEYETKFKNQEKRMEKIKQKAKEMQETkkkLLD 996
Cdd:pfam12128  731 LALLKAAIAARRSGAKAELKAletwykrdlaslgvDPDVIAKLKreiRTLERKIERIAVRRQEVLRYFDWYQET---WLQ 807

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  997 QEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgISDTVSRLEENQRQQIESLTG--AHQRKLDDVIEAWEKKLSQQ 1074
Cdd:pfam12128  808 RRPRLATQLSNIERAISELQQQLARLIADTKLRRAK-LEMERKASEKQQVRLSENLRGlrCEMSKLATLKEDANSEQAQG 886

                          650       660
                   ....*....|....*....|....*
gi 1907198992 1075 AAELRDKHAEQMEEKEQGLGELRQK 1099
Cdd:pfam12128  887 SIGERLAQLEDLKLKRDYLSESVKK 911
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 621-959 2.73e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.11  E-value: 2.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  621 AEKNKHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQA----HIQDM 696
Cdd:COG3096    278 NERRELSERALELRRELFGARRQLAEEQYRL--VEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQekieRYQED 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  697 NEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaelEEQRR--HHQREVGSISEQQELTVRR 774
Cdd:COG3096    356 LEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALD---VQQTRaiQYQQAVQALEKARALCGLP 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  775 --AEKALKDELSRLGALLDERDEHLRERQARVQDLEAH----------LQKSAGE------------------------- 817
Cdd:COG3096    433 dlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAArrqfekayelVCKIAGEversqawqtarellrryrsqqalaq 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  818 ----LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLER 893
Cdd:COG3096    513 rlqqLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRA 592

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992  894 QRSELEEKVRSLAQLQDS--QLKNSTVEKEQARQSLMEKeniiLQMREEQAKEIEILKQTLSSKEESI 959
Cdd:COG3096    593 RIKELAARAPAWLAAQDAleRLREQSGEALADSQEVTAA----MQQLLEREREATVERDELAARKQAL 656
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 801-1022 2.89e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.16  E-value: 2.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  801 QARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEE 880
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  881 LDAQRAQVQQLER--QRSELEEKVRSLAQLQDSQ--LKNSTVEKE--QARQSLMEKENIILQMREEQAKEIEILKQTLSS 954
Cdd:COG4942     99 LEAQKEELAELLRalYRLGRQPPLALLLSPEDFLdaVRRLQYLKYlaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992  955 KEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQ 1022
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
338-890 3.29e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.08  E-value: 3.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  338 QQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQmLETLELKEDEIAQLRSHIK 417
Cdd:COG4913    287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLERE-IERLERELEERERRRARLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  418 QMTTQGEElreqKEKSERAAFEEL-EKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERlRLQHELSRVRQeaasmAK 496
Cdd:COG4913    366 ALLAALGL----PLPASAEEFAALrAEAAALLEALEEELEALEEALAEAEAALRDLRRELR-ELEAEIASLER-----RK 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  497 KNSEEQVAALQKLHAEELASKEQELS--------RRLEAR-----EREL----------QEQMRIALEKSRSEYLK--LT 551
Cdd:COG4913    436 SNIPARLLALRDALAEALGLDEAELPfvgelievRPEEERwrgaiERVLggfaltllvpPEHYAAALRWVNRLHLRgrLV 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  552 QEKEQQESLALEELELQKKAILteseNKLQELGQEAEAYRTRILELETSLEK--SLQESKT---------QSEHLAVHLE 620
Cdd:COG4913    516 YERVRTGLPDPERPRLDPDSLA----GKLDFKPHPFRAWLEAELGRRFDYVCvdSPEELRRhpraitragQVKGNGTRHE 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  621 AEKNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQhQAAVEELREKYQQEKDALLKEKESLF--------QAH 692
Cdd:COG4913    592 KDDRRRIRSRYVLGFDNRAKLAALEAELAEL-EEELAEAEER-LEALEAELDALQERREALQRLAEYSWdeidvasaERE 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  693 IQDmNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTV 772
Cdd:COG4913    670 IAE-LEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR 748

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  773 RRAEKALKDelsrlgALLDERDEHLRER-QARVQDLEAHLQKSAGELQQALAKL----DLLHSEQSAAREQAGAYEEQLA 847
Cdd:COG4913    749 ALLEERFAA------ALGDAVERELRENlEERIDALRARLNRAEEELERAMRAFnrewPAETADLDADLESLPEYLALLD 822

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1907198992  848 QMQQKVL-DLETE-KSLLTKQvveMETHKKHVCEELDAQRAQVQQ 890
Cdd:COG4913    823 RLEEDGLpEYEERfKELLNEN---SIEFVADLLSKLRRAIREIKE 864
PTZ00121 PTZ00121
MAEBL; Provisional
 706-1514 4.15e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 4.15e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  706 KKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQRevgsiseqqeltVRRAEKALKDELSR 785
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAED------------ARKAEEARKAEDAK 1152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  786 LGALLDERDEHLRERQARVQDlEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQlaQMQQKVLDLETEKSLltK 865
Cdd:PTZ00121  1153 RVEIARKAEDARKAEEARKAE-DAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEE--RKAEEARKAEDAKKA--E 1227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  866 QVVEMETHKKhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEI 945
Cdd:PTZ00121  1228 AVKKAEEAKK---DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA 1304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  946 EILKQTLSSKEESisilhEEYETKFKNQEKRMEKIKQKAKEmqetkKKLLDQEAKLKKELENTVLELSQKEKQfnaqile 1025
Cdd:PTZ00121  1305 DEAKKKAEEAKKA-----DEAKKKAEEAKKKADAAKKKAEE-----AKKAAEAAKAEAEAAADEAEAAEEKAE------- 1367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1026 maqansagiSDTVSRLEENQRQQiesltgAHQRKLDDVIEAWEKKlsqQAAELRDKHAEQMEEKEQGlgelrqkvrivQS 1105
Cdd:PTZ00121  1368 ---------AAEKKKEEAKKKAD------AAKKKAEEKKKADEAK---KKAEEDKKKADELKKAAAA-----------KK 1418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1106 EKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAvivslsERESQLQSQVEKLEAdlgcslSEKLSLQEELAELKLLAD 1185
Cdd:PTZ00121  1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA------EEAKKAEEAKKKAEE------AKKADEAKKKAEEAKKAD 1486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1186 KSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADA 1265
Cdd:PTZ00121  1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKA 1566

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1266 ILARLSQCQRHTATVGEALLRRMGQVSELEaqLTQLTEEQRTLKSsfQQVTNQLEEKEKQIKTMKAdieglltekEALQQ 1345
Cdd:PTZ00121  1567 EEAKKAEEDKNMALRKAEEAKKAEEARIEE--VMKLYEEEKKMKA--EEAKKAEEAKIKAEELKKA---------EEEKK 1633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1346 EGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQhee 1425
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKK--- 1710

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1426 qelqlqaqLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLK 1505
Cdd:PTZ00121  1711 --------EAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782


                   ....*....
gi 1907198992 1506 EDLDRQNKK 1514
Cdd:PTZ00121  1783 EELDEEDEK 1791
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
807-1035 4.48e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 55.41  E-value: 4.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  807 LEAHLQKSAGELQQALAKLDllhSEQSAAREQAGAYEEQLAQMQQK--VLDLETEKSLLTKQVVEMETHKKHVCEELDAQ 884
Cdd:COG3206    162 LEQNLELRREEARKALEFLE---EQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELAEA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  885 RAQVQQLERQRSELEEKVRSLAQLQ-----DSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESI 959
Cdd:COG3206    239 EARLAALRAQLGSGPDALPELLQSPviqqlRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  960 SILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL--LDQEAKLKKELENTVL------ELSQKEKQFNAQILEMAQANS 1031
Cdd:COG3206    319 EAELEALQAREASLQAQLAQLEARLAELPELEAELrrLEREVEVARELYESLLqrleeaRLAEALTVGNVRVIDPAVVPL 398


                   ....
gi 1907198992 1032 AGIS 1035
Cdd:COG3206    399 KPVS 402
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 766-1330 5.02e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.03  E-value: 5.02e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  766 EQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSeqsaareqagayeeQ 845
Cdd:TIGR04523  130 EKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKN--------------K 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  846 LAQMQQKVLDLETEKS---LLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQD---SQLKNSTVE 919
Cdd:TIGR04523  196 LLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNkikKQLSEKQKE 275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  920 KEQARQSLMEKENIILQMReeqaKEIEILKQtlsskeESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA 999
Cdd:TIGR04523  276 LEQNNKKIKELEKQLNQLK----SEISDLNN------QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQIS 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1000 KLKKELENTVLELSQKEKQfnaqilemaqansagisdtvsrLEENQrQQIESLTGAHQRKLDDVieaweKKLSQQAAELR 1079
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRE----------------------LEEKQ-NEIEKLKKENQSYKQEI-----KNLESQINDLE 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1080 DKHAEQMEEKEQglgeLRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKL 1159
Cdd:TIGR04523  398 SKIQNQEKLNQQ----KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVL 473

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1160 EADLGCSLSEKLSLQEELAE-----LKLLADKSQL--RVSELTGQVQAA---EKELQSCKSLHELSKKSLEDKSLNLKSL 1229
Cdd:TIGR04523  474 SRSINKIKQNLEQKQKELKSkekelKKLNEEKKELeeKVKDLTKKISSLkekIEKLESEKKEKESKISDLEDELNKDDFE 553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1230 L--EELASQLDSRCERTKALLEAKTNELVctSRDKADAILARLSQCQRhtaTVGEALLRRMGQVSELEAQLTQLTEEQRT 1307
Cdd:TIGR04523  554 LkkENLEKEIDEKNKEIEELKQTQKSLKK--KQEEKQELIDQKEKEKK---DLIKEIEEKEKKISSLEKELEKAKKENEK 628

                          570       580
                   ....*....|....*....|...
gi 1907198992 1308 LKSSFQQVTNQLEEKEKQIKTMK 1330
Cdd:TIGR04523  629 LSSIIKNIKSKKNKLKQEVKQIK 651
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 352-686 5.26e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.13  E-value: 5.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  352 KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQmletlelkedeiAQLRSHIKQMTTQGEELREQKE 431
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQ------------AEMDRQAAIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  432 KSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKaVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHA 511
Cdd:pfam17380  349 ELERIRQEERKRELERIRQEEIAMEISRMRELERLQ-MERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRA 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  512 EELASKEQELSRRLEARERELqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKlQELGQEAEAYR 591
Cdd:pfam17380  428 EQEEARQREVRRLEEERAREM-ERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRR-KILEKELEERK 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  592 TRILELETslEKSLQESKTQSEHLAVHLEAEKNKHNKELTalAEQHRTEVEGLQQQQDSLWTERlqslsqQHQAAVEELR 671
Cdd:pfam17380  506 QAMIEEER--KRKLLEKEMEERQKAIYEEERRREAEEERR--KQQEMEERRRIQEQMRKATEER------SRLEAMERER 575

                          330
                   ....*....|....*
gi 1907198992  672 EKYQQEKDALLKEKE 686
Cdd:pfam17380  576 EMMRQIVESEKARAE 590
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 569-1685 5.52e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.44  E-value: 5.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  569 KKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQES---KTQSEHL---------------AVHLE--------AE 622
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSihlEKEIKDLfdkyleiddeiiyinKLKLElkekikniSD 614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  623 KNKHNK---ELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQ--------- 690
Cdd:TIGR01612  615 KNEYIKkaiDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNELSSIVKenaidnted 694

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  691 -AHIQDMNEKTLEKLDKKQ-MELESVSSELSEALRARDQLAEELSvlrgdadKMKQALEAELeeqrrhhQREVGSISEQq 768
Cdd:TIGR01612  695 kAKLDDLKSKIDKEYDKIQnMETATVELHLSNIENKKNELLDIIV-------EIKKHIHGEI-------NKDLNKILED- 759

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  769 eltVRRAEKALKdelSRLGALLDERDEhLRERQARVQDLEAHL--QKSAGELQQALAKLDLLHSEQSAarEQAGAYEEQL 846
Cdd:TIGR01612  760 ---FKNKEKELS---NKINDYAKEKDE-LNKYKSKISEIKNHYndQINIDNIKDEDAKQNYDKSKEYI--KTISIKEDEI 830

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  847 AQMQQKVLDLETEKSLLTKQVVEMETHKKhvcEELDAQRAQVQQL---------ERQRSELEEKVRSLAQLQDSqlKNST 917
Cdd:TIGR01612  831 FKIINEMKFMKDDFLNKVDKFINFENNCK---EKIDSEHEQFAELtnkikaeisDDKLNDYEKKFNDSKSLINE--INKS 905

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  918 VEKEQARQSLMEKEN-----------IILQMREEQAKEIEILKQTLSSKEESISIlHEEYETKFKN----QEKRMEKIKQ 982
Cdd:TIGR01612  906 IEEEYQNINTLKKVDeyikicentkeSIEKFHNKQNILKEILNKNIDTIKESNLI-EKSYKDKFDNtlidKINELDKAFK 984

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  983 KAK------EMQETKKKLLDQEAKLKKELENTVL-ELSQKEKQFNAQILEMAQANS----------AGISDTVSRLEENQ 1045
Cdd:TIGR01612  985 DASlndyeaKNNELIKYFNDLKANLGKNKENMLYhQFDEKEKATNDIEQKIEDANKnipnieiaihTSIYNIIDEIEKEI 1064

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1046 RQQIESLTGAHQRKLDDVIEAWEK--------KLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKE---- 1113
Cdd:TIGR01612 1065 GKNIELLNKEILEEAEINITNFNEikeklkhyNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKseny 1144

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1114 VARLKEAVSG-QDVALAGLQGQ----LEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQE----------ELA 1178
Cdd:TIGR01612 1145 IDEIKAQINDlEDVADKAISNDdpeeIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEvkginlsygkNLG 1224

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1179 ELKLLADKSQLRVSELTgqVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCT 1258
Cdd:TIGR01612 1225 KLFLEKIDEEKKKSEHM--IKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISD 1302

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1259 SRDKADAIL-----------------ARLSQCQRHTATVGEAL-----LRRMGQVSELEAQLTQLTEEQRTLKSSFQQVT 1316
Cdd:TIGR01612 1303 IREKSLKIIedfseesdindikkelqKNLLDAQKHNSDINLYLneianIYNILKLNKIKKIIDEVKEYTKEIEENNKNIK 1382

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1317 NQLEEKEKQIKTMKAD---------IEGLLTEK---EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLRE-ELS 1383
Cdd:TIGR01612 1383 DELDKSEKLIKKIKDDinleeckskIESTLDDKdidECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNiEMA 1462

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1384 EKKSE-IASLSKQ--LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKeKMSALEqvdhWSN 1460
Cdd:TIGR01612 1463 DNKSQhILKIKKDnaTNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLN-KYSALA----IKN 1537

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1461 KFSEWKKKAQSRLAQhqstIKDLQAQLDVKATDAREKEEQIcllkedldrqnkKFECLKGEMEVRKS-KMEKKECDLETA 1539
Cdd:TIGR01612 1538 KFAKTKKDSEIIIKE----IKDAHKKFILEAEKSEQKIKEI------------KKEKFRIEDDAAKNdKSNKAAIDIQLS 1601

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1540 LKTQTARVVELEDCVTQRK---KEVESLNETLKNYN-QQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETvlrlrehvs 1615
Cdd:TIGR01612 1602 LENFENKFLKISDIKKKINdclKETESIEKKISSFSiDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDK--------- 1672

                         1210      1220      1230      1240      1250      1260      1270
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198992 1616 sleaelgtvKKELEHVNSSVKSRDGELKALEDKLELESAAKV-ELKRKAEQKIAAIRKQLLSQMEEKTQRY 1685
Cdd:TIGR01612 1673 ---------KKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIkEIAIANKEEIESIKELIEPTIENLISSF 1734
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
332-900 7.86e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.66  E-value: 7.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  332 KTLEMLQQRVKRQENLLQRC---KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDE 408
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYeeqREQARETRDEADEVLEEHEERREELETLEAEIEDLR------------ETIAETERE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  409 IAQLRSHIKQMTTQGEELREqkEKSERAAFEELEKAlstAQKTEDAQRRmkmEMDEQMKAVERASEEERLRLQhelsRVR 488
Cdd:PRK02224   274 REELAEEVRDLRERLEELEE--ERDDLLAEAGLDDA---DAEAVEARRE---ELEDRDEELRDRLEECRVAAQ----AHN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  489 QEAASMAKKnseeqvaalqklhAEELASKEQELSRRLEARERELQEQmRIALEKSRSEYLKLTQEKEQQESLALEELELq 568
Cdd:PRK02224   342 EEAESLRED-------------ADDLEERAEELREEAAELESELEEA-REAVEDRREEIEELEEEIEELRERFGDAPVD- 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  569 kkaiLTESENKLQELGQEAEAYRTRILELETSLeKSLQESKTQSEHL---------------AVHLEA--EKNKHNKELT 631
Cdd:PRK02224   407 ----LGNAEDFLEELREERDELREREAELEATL-RTARERVEEAEALleagkcpecgqpvegSPHVETieEDRERVEELE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  632 ALAEQHRTEVEGLQQQqdslwTERLQSLSQQhQAAVEELREKYQQEKDALLKEKESLfqahiqDMNEKTLEKLDKKQMEL 711
Cdd:PRK02224   482 AELEDLEEEVEEVEER-----LERAEDLVEA-EDRIERLEERREDLEELIAERRETI------EEKRERAEELRERAAEL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  712 ESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRhhqrevgsISEQQEL--TVRRAEKALKDELSRLGAL 789
Cdd:PRK02224   550 EAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER--------IRTLLAAiaDAEDEIERLREKREALAEL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  790 LDERDEHLRERQARVQDLEAHLQKSAGElqqalakldllhseqsAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQV-- 867
Cdd:PRK02224   622 NDERRERLAEKRERKRELEAEFDEARIE----------------EAREDKERAEEYLEQVEEKLDELREERDDLQAEIga 685

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1907198992  868 VEMETHK-KHVCEELDAQRAQVQQLERQRSELEE 900
Cdd:PRK02224   686 VENELEElEELRERREALENRVEALEALYDEAEE 719
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
499-1109 1.03e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.30  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  499 SEEQVAALQKLHAEELASKEQELSRrLEARERELQEQmriaLEKSRSEYLKLTQEKEQQESLALEELELQKKaiLTESEN 578
Cdd:PRK03918   187 RTENIEELIKEKEKELEEVLREINE-ISSELPELREE----LEKLEKEVKELEELKEEIEELEKELESLEGS--KRKLEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  579 KLQELGQEAEAYRTRILELETSLE--KSLQESKTQSEHLaVHLEAEKNKHNKELTALAEQHRTEVEGLQqqqdslwtERL 656
Cdd:PRK03918   260 KIRELEERIEELKKEIEELEEKVKelKELKEKAEEYIKL-SEFYEEYLDELREIEKRLSRLEEEINGIE--------ERI 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  657 QSLSQQhQAAVEELREKYQ--QEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSV 734
Cdd:PRK03918   331 KELEEK-EERLEELKKKLKelEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISK 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  735 LRGDADKMKQaleaeleeqrrhhqrevgsISEQQELTVRRAEKAlKDELSRLGALLDE--RDEHLRERQARVQDLEAHLQ 812
Cdd:PRK03918   410 ITARIGELKK-------------------EIKELKKAIEELKKA-KGKCPVCGRELTEehRKELLEEYTAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  813 KSAGELQQALAKLDLLHSEQSAAREQAGAYE--EQLAQMQQKVLDLETEKslLTKQVVEMETHKkhvcEELDAQRAQVQQ 890
Cdd:PRK03918   470 EIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYNLEE--LEKKAEEYEKLK----EKLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  891 LERQRSELEEKVRSLAQLQDsqlKNSTVEKeqarqslmEKENIILQMREEQAKEIEILKQTLSSKEEsisiLHEEYeTKF 970
Cdd:PRK03918   544 LKKELEKLEELKKKLAELEK---KLDELEE--------ELAELLKELEELGFESVEELEERLKELEP----FYNEY-LEL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  971 KNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEEnqrqQIE 1050
Cdd:PRK03918   608 KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRA----ELE 683

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198992 1051 SLtgahqRKLDDVIEAWEKKLSQQAAELRD--KHAEQMEEKEQGLGELRQKVRIVQSEKEE 1109
Cdd:PRK03918   684 EL-----EKRREEIKKTLEKLKEELEEREKakKELEKLEKALERVEELREKVKKYKALLKE 739
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
407-1025 1.48e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  407 DEIAQLRSHIKQMTTQGEELREQKEKSeRAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVErASEEERLRLQHELSR 486
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQREQA-RETRDEADEVLEEHEERREELETLEAEIEDLRETIA-ETEREREELAEEVRD 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  487 VRQEAASMAKKNSEEQV-AALQKLHAEELASKEQELSRRLEARERELQEQmRIALEKSRSEYLKLTQEKEqqeslaleel 565
Cdd:PRK02224   284 LRERLEELEEERDDLLAeAGLDDADAEAVEARREELEDRDEELRDRLEEC-RVAAQAHNEEAESLREDAD---------- 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  566 elqkkailtesenklqELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaeknkhnkELTALAEQHRTEVEGLQ 645
Cdd:PRK02224   353 ----------------DLEERAEELREEAAELESELEEAREAVEDRREEIE------------ELEEEIEELRERFGDAP 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  646 QQQDSLwTERLQSLSQQHQAAVE---ELREKYQQEKDALlKEKESLFQAHIQDMNEKTLEkldkkqmelesvSSELSEAL 722
Cdd:PRK02224   405 VDLGNA-EDFLEELREERDELREreaELEATLRTARERV-EEAEALLEAGKCPECGQPVE------------GSPHVETI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  723 RARDQLAEELSVLRGDADKMKQALEAELEEqrrhhqrevgsiSEQQELTVRRAEKaLKDELSRLGALLDERDEHLRERQA 802
Cdd:PRK02224   471 EEDRERVEELEAELEDLEEEVEEVEERLER------------AEDLVEAEDRIER-LEERREDLEELIAERRETIEEKRE 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  803 RVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLtkqvvEMETHKKHVCEELD 882
Cdd:PRK02224   538 RAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLL-----AAIADAEDEIERLR 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  883 AQRAQVQQLERQR----SELEEKVRSL-AQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKeieiLKQTLSSKEE 957
Cdd:PRK02224   613 EKREALAELNDERrerlAEKRERKRELeAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDD----LQAEIGAVEN 688

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  958 SIsilheeyetkfknqeKRMEKIKQKAKEMQETKKKL--LDQEAklkKELENTVLELSQKEKQFNAQILE 1025
Cdd:PRK02224   689 EL---------------EELEELRERREALENRVEALeaLYDEA---EELESMYGDLRAELRQRNVETLE 740
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1190-1718 1.66e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1190 RVSELTGQVQAAEK--ELQSCKSLHELSKKSLEDKSLNLK-SLLEELASQLDSRCERTKALLEAKTNEL------VCTSR 1260
Cdd:COG1196    201 QLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELeelrleLEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1261 DKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKssfqqvtNQLEEKEKQIKTMKADIEGLLTEK 1340
Cdd:COG1196    281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1341 EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISpsdKAEAISALS 1420
Cdd:COG1196    354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1421 KQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQStiKDLQAQLDVKATDAREKEEQ 1500
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1501 ICLLKEDLDRQNKKFECLKGEMEVRKSkmekkecdLETALktQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT--- 1577
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAA--------YEAAL--EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflp 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1578 ----EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGEL-KALEDKLELE 1652
Cdd:COG1196    579 ldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLReVTLEGEGGSA 658

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198992 1653 SAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1718
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 687-911 1.82e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 1.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  687 SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALeAELEEQRRHHQREVGSISE 766
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI-RALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  767 QQElTVRRAEKALKDELSRLGALLderdehlrERQARVQDLEAHLqkSAGELQQALAKLDLLHSEQSAAREQAGAYEEQL 846
Cdd:COG4942     91 EIA-ELRAELEAQKEELAELLRAL--------YRLGRQPPLALLL--SPEDFLDAVRRLQYLKYLAPARREQAEELRADL 159

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992  847 AQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDS 911
Cdd:COG4942    160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 577-926 2.11e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.42  E-value: 2.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  577 ENKLQELGQEAEAYRTRILELETSLEK--SLQESKTQ--SEHLAVHLEAEKnkhnKELTALAEQHRTEVEGLQQQQdslw 652
Cdd:COG3096    784 EKRLEELRAERDELAEQYAKASFDVQKlqRLHQAFSQfvGGHLAVAFAPDP----EAELAALRQRRSELERELAQH---- 855

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  653 terlQSLSQQHQAAVEELREKyQQEKDALLKEKESLFQAHIQDMnektLEKLDKKQMELESVSSELSEALRARDQLAEEL 732
Cdd:COG3096    856 ----RAQEQQLRQQLDQLKEQ-LQLLNKLLPQANLLADETLADR----LEELREELDAAQEAQAFIQQHGKALAQLEPLV 926

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  733 SVLRGDA---DKMKQALEAELEEQRRHHQRevgsISEQQELTVRRAEKALKDELSRLGALlDERDEHLRER-----QARV 804
Cdd:COG3096    927 AVLQSDPeqfEQLQADYLQAKEQQRRLKQQ----IFALSEVVQRRPHFSYEDAVGLLGEN-SDLNEKLRARleqaeEARR 1001

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  805 QDLEAhLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSlltkqvvemETHKKHVCEELDAQ 884
Cdd:COG3096   1002 EAREQ-LRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEERA---------RIRRDELHEELSQN 1071

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1907198992  885 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 926
Cdd:COG3096   1072 RSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQA 1113
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 332-698 2.17e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 2.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  332 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDEIAQ 411
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE------------EELAEAEAEIEE 786

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  412 LRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMkmemdeqmkaverASEEERLRLQHELSRVRQEA 491
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI-------------AATERRLEDLEEQIEELSED 853

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  492 ASMAKKNSEEQVAALQKLHAE-ELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEqqeslaleelelQKK 570
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESElEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE------------ELR 921

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  571 AILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQds 650
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELK-- 999

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198992  651 lwtERLQSLSQQHqAAVEELREKYQQEKDALLKEKESLFQAHIQDMNE 698
Cdd:TIGR02168 1000 ---ERYDFLTAQK-EDLTEAKETLEEAIEEIDREARERFKDTFDQVNE 1043
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 778-1004 2.48e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  778 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLE 857
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  858 TE----KSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENI 933
Cdd:COG4942     97 AEleaqKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198992  934 ILQMREEQAKEIEILKQTLSSKEESISILheeyETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKE 1004
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARL----EKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1918-2161 2.84e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 2.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1918 EDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK------LSKEVARLQKELRALR-REHQQELDILKREcEQE 1990
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKaerykeLKAELRELELALLVLRlEELREELEELQEE-LKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1991 AEEKLKQEQEDLELKHTStLKQLMREFNtQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRR 2070
Cdd:TIGR02168  251 AEEELEELTAELQELEEK-LEELRLEVS-ELEEEIEELQKELYALANEISRLEQQ-KQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2071 TARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSVTilELQTQLAQKTTLISDSKLKEQELREQVHN 2150
Cdd:TIGR02168  328 LESKLDE-LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE--ELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250
                   ....*....|.
gi 1907198992 2151 LEDRLKRYEKN 2161
Cdd:TIGR02168  405 LEARLERLEDR 415
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1320-2115 2.86e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.05  E-value: 2.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1320 EEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAAS----EKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQ 1395
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKlkeqAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1396 LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQ 1475
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1476 HQSTIKDLQAQLDVKATDAREKEEQICLLKEdldrQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVT 1555
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEE----EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1556 QRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSV 1635
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1636 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLK 1715
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1716 NLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCT--HKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRA 1793
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVleIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1794 LSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVK 1873
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1874 ELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAER 1953
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEE 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1954 DKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQ 2033
Cdd:pfam02463  802 ELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2034 ETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 2113
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER 961


                   ..
gi 1907198992 2114 TK 2115
Cdd:pfam02463  962 NK 963
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1302-1514 2.97e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1302 TEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREE 1381
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1382 LSEKKSEIASLSKQLSDLGAQ--LESSISPSDKAEAISALS---------KQHEEQELQLQAQLQELSLKVDALSKEKMS 1450
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQppLALLLSPEDFLDAVRRLQylkylaparREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198992 1451 ALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKK 1514
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK11281 PRK11281
mechanosensitive channel MscK;
764-1114 3.58e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.61  E-value: 3.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  764 ISEQQELTVrrAEKALKDELSRLGALLDERDEHlrerQARVQDLEAHLQKSAGELQQALAKLDLL-HSEQSAAREQAGAY 842
Cdd:PRK11281    48 LNKQKLLEA--EDKLVQQDLEQTLALLDKIDRQ----KEETEQLKQQLAQAPAKLRQAQAELEALkDDNDEETRETLSTL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  843 -----EEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSEL---------EEKVRSLAQL 908
Cdd:PRK11281   122 slrqlESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGkvggkalrpSQRVLLQAEQ 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  909 QDSQLKNstvekEQARQSLmeKENIILQM-----REEQAKEIEILKQTLSSKEESISilheeyetkfknqEKRMEKIKQK 983
Cdd:PRK11281   202 ALLNAQN-----DLQRKSL--EGNTQLQDllqkqRDYLTARIQRLEHQLQLLQEAIN-------------SKRLTLSEKT 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  984 AKEMQETKKK-------LLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQansagISDTVSRLEENQRQQIESLTGA- 1055
Cdd:PRK11281   262 VQEAQSQDEAariqanpLVAQELEINLQLSQRLLKATEKLNTLTQQNLRVKN-----WLDRLTQSERNIKEQISVLKGSl 336

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1056 --------HQRKL--DDVIeaweKKLSQQAAELRDKHAEQMEEKEQgLGELRQKV-RIVQSEKEELTKEV 1114
Cdd:PRK11281   337 llsrilyqQQQALpsADLI----EGLADRIADLRLEQFEINQQRDA-LFQPDAYIdKLEAGHKSEVTDEV 401
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1038-1718 4.40e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 4.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1038 VSRLEENQRQQIESLtgahQRKLDDVIEAWEKK---LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEV 1114
Cdd:pfam15921   76 IERVLEEYSHQVKDL----QRRLNESNELHEKQkfyLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1115 ARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLR---- 1190
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILReldt 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1191 -VSELTGQVQAAEKELQSCKSlhelskksledkslNLKSLLEELASQLDSRCERTKALLEAKTN---ELVCTSRDKADAI 1266
Cdd:pfam15921  232 eISYLKGRIFPVEDQLEALKS--------------ESQNKIELLLQQHQDRIEQLISEHEVEITgltEKASSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1267 LARLSQCQRHTATVGEALLRrmgQVSELEAQLTQLTEEQRTLKSSFQqvtNQLEEKEKQIKTMKADIEGLLTEKEALQQE 1346
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSELREAKRMYE---DKIEELEKQLVLANSELTEARTERDQFSQE 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1347 GG------QQRQAASEKESCITQLKKELAENI------NAVTL--LREELSEKKSEIASLSKQL----SDLGAQLESSIS 1408
Cdd:pfam15921  372 SGnlddqlQKLLADLHKREKELSLEKEQNKRLwdrdtgNSITIdhLRRELDDRNMEVQRLEALLkamkSECQGQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1409 P----SDKAEAISALSKQHEEQELQLQAQLQELSLKVDALS-------------KEKMSALEQVDHWSNKFS---EWKKK 1468
Cdd:pfam15921  452 AiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLEssertvsdltaslQEKERAIEATNAEITKLRsrvDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1469 AQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNK---KFECLKGEMEVRKSKMEKKECDLETALK---- 1541
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQefki 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1542 ---TQTARVVELE----DCVTQRKKEVESLNETL---KNYNQQRDTEHSGLVQRLQHLEELGEEKD-------NKVREAE 1604
Cdd:pfam15921  612 lkdKKDAKIRELEarvsDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEvlkrnfrNKSEEME 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1605 ETVLRLREHVSSLEAELGTVKKELEHVNSS--------------VKSRDGELKALEDKLELESAAKVELKRKaeqkiaai 1670
Cdd:pfam15921  692 TTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgmqkqITAKRGQIDALQSKIQFLEEAMTNANKE-------- 763

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198992 1671 rKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1718
Cdd:pfam15921  764 -KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1919-2161 4.86e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 4.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1919 DRPEENSQSHEIQSNVGTVDGLRSDLESkltgaERDKQKLSKEVARLQKELRALRRE---HQQELDILKRECEQEAEEKL 1995
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALED-----AREQIELLEPIRELAERYAAARERlaeLEYLRAALRLWFAQRRLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1996 KQEQEDLELKHTstlkqlmrefntQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRY 2075
Cdd:COG4913    294 EAELEELRAELA------------RLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRR 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2076 EEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDsvtilELQTQLAqkttlisDSKLKEQELREQVHNLEDRL 2155
Cdd:COG4913    362 AR-LEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE-----ALEEALA-------EAEAALRDLRRELRELEAEI 428


                   ....*.
gi 1907198992 2156 KRYEKN 2161
Cdd:COG4913    429 ASLERR 434
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 675-1707 5.13e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.10  E-value: 5.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  675 QQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQR 754
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  755 RHHQREvgsisEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSA 834
Cdd:pfam01576   82 SRLEEE-----EERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  835 AREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLaQLQDSQLK 914
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAEL-QAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  915 NSTVEKEQARQSLMEKeniilqMREEQAKEIEILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL 994
Cdd:pfam01576  236 AQLAKKEEELQAALAR------LEEETAQKNNALKK-IRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  995 LD--------QEAKLKKELENTVLE--LSQKEKQFNAQILEMAQANSAGISDTVSRLE---------ENQRQQIESLTGA 1055
Cdd:pfam01576  309 EDtldttaaqQELRSKREQEVTELKkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEqakrnkanlEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1056 HQRKLDDV------IEAWEKKLSQQAAELRDKHAE---QMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDV 1126
Cdd:pfam01576  389 LQAELRTLqqakqdSEHKRKKLEGQLQELQARLSEserQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1127 ALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1206
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1207 SCKSLHELSKKSLEDKSLNLKSL----------LEELASQLDSRCERTKAL---------LEAKTNELVCTSRDKADAIL 1267
Cdd:pfam01576  549 RLQRELEALTQQLEEKAAAYDKLektknrlqqeLDDLLVDLDHQRQLVSNLekkqkkfdqMLAEEKAISARYAEERDRAE 628

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1268 ARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEG 1347
Cdd:pfam01576  629 AEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1348 GQQRQAASEKESCITQLKKELAENINAvtllREELSEKKSEiaSLSKQLSDLGAQLESsiSPSDKAEAISALSKqheeqe 1427
Cdd:pfam01576  709 QATEDAKLRLEVNMQALKAQFERDLQA----RDEQGEEKRR--QLVKQVRELEAELED--ERKQRAQAVAAKKK------ 774

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1428 lqLQAQLQELSLKVDALSKEKMSALEQVdhwsnkfsewkKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEE-------Q 1500
Cdd:pfam01576  775 --LELDLKELEAQIDAANKGREEAVKQL-----------KKLQAQMKDLQRELEEARASRDEILAQSKESEKklknleaE 841

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1501 ICLLKEDL---DRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT 1577
Cdd:pfam01576  842 LLQLQEDLaasERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQ 921

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1578 EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREhvssleaELGTVKKELEhvnSSVKSRDGELKALEDKLELES---A 1654
Cdd:pfam01576  922 LTTELAAERSTSQKSESARQQLERQNKELKAKLQE-------MEGTVKSKFK---SSIAALEAKIAQLEEQLEQESrerQ 991

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198992 1655 AKVELKRKAEQKIaairKQLLSQME------EKTQRYAKDTENRLSELSAQLKEREKQV 1707
Cdd:pfam01576  992 AANKLVRRTEKKL----KEVLLQVEderrhaDQYKDQAEKGNSRMKQLKRQLEEAEEEA 1046
PTZ00121 PTZ00121
MAEBL; Provisional
 541-1249 5.53e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 5.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  541 EKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRtRILELETSLEKSLQESKTQSEHLAVHLE 620
Cdd:PTZ00121  1090 DEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDAR-KAEEARKAEDAKRVEIARKAEDARKAEE 1168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  621 AEKNKHNKELTAL--AEQHRTEVEgLQQQQDSLWTERLQSLSQQHQAavEELReKYQQEKDAllkekESLFQAHIQDMNE 698
Cdd:PTZ00121  1169 ARKAEDAKKAEAArkAEEVRKAEE-LRKAEDARKAEAARKAEEERKA--EEAR-KAEDAKKA-----EAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  699 KTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQRevgsISEQQELTVRRAEKA 778
Cdd:PTZ00121  1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEE----KKKADEAKKKAEEAK 1315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  779 LKDELSRLGALLDERDEHLRERqarvqdleAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLET 858
Cdd:PTZ00121  1316 KADEAKKKAEEAKKKADAAKKK--------AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA 1387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  859 EKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiiLQMR 938
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEE--AKKK 1465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  939 EEQAKEIEILKQTLSSKEESISILHEEYETKFKNQE-KRMEKIKQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEK 1017
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEaKKAAEAKKKADEAKKAEEAKKADEAK-KAEEAKKADEAKKAEE 1544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1018 QFNAQilEMAQANSAGISDTVSRLEENQRQQ---------IESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEE 1088
Cdd:PTZ00121  1545 KKKAD--ELKKAEELKKAEEKKKAEEAKKAEedknmalrkAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1089 KE-QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQ--KSAVIVSLSERESQLQSQVEKLEADLGC 1165
Cdd:PTZ00121  1623 EElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1166 SLSEklsLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTK 1245
Cdd:PTZ00121  1703 KAEE---LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779


                   ....
gi 1907198992 1246 ALLE 1249
Cdd:PTZ00121  1780 VIEE 1783
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1472-2161 5.81e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 5.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1472 RLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELE 1551
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1552 DCVTQRKKEVESLNETLKNYNQQR-----------DTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAE 1620
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEqlrvkekigelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELERE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1621 LGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRkaEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQL 1700
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD--ELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1701 KEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDctHKACKERLCMLQRRLSEKEKLLRRLEQGEG 1780
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE--LYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1781 EARPSQPE-------------------------------AQHRALSGKL---------DCTRARQLEDHVLIGCLPEELE 1820
Cdd:TIGR02169  501 ASEERVRGgraveevlkasiqgvhgtvaqlgsvgeryatAIEVAAGNRLnnvvveddaVAKEAIELLKRRKAGRATFLPL 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1821 EKMKCSLIVSQPMGEETGNNTGV-----KQNWASVVDSV-QKTLQEKELTC---QALEQRVKELESDLVRERGA------ 1885
Cdd:TIGR02169  581 NKMRDERRDLSILSEDGVIGFAVdlvefDPKYEPAFKYVfGDTLVVEDIEAarrLMGKYRMVTLEGELFEKSGAmtggsr 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1886 --HRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVA 1963
Cdd:TIGR02169  661 apRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1964 RLQKELRALRRE---HQQELDILKRECE--QEAEEKLKQEQEDLElkhtstlKQLMREFNTQLAQKEQELERTVQETIDK 2038
Cdd:TIGR02169  741 ELEEDLSSLEQEienVKSELKELEARIEelEEDLHKLEEALNDLE-------ARLSHSRIPEIQAELSKLEEEVSRIEAR 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2039 AQEVEAELLESHQEEtQQLHRKIAEKEDDLRRTARRYEEIlDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSV 2118
Cdd:TIGR02169  814 LREIEQKLNRLTLEK-EYLEKEIQELQEQRIDLKEQIKSI-EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKER 891

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907198992 2119 TILE-----LQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2161
Cdd:TIGR02169  892 DELEaqlreLERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
332-940 6.05e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.60  E-value: 6.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  332 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLD---ERLQELEKMKGMvITETKRQM------LETL 402
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEE-IEELEKELeslegsKRKL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  403 ELK----EDEIAQLRSHIKQMTTQGEELREQKEKSERaaFEELEKALstaqktedaqrrmkmemdEQMKAVERASEEERL 478
Cdd:PRK03918   258 EEKirelEERIEELKKEIEELEEKVKELKELKEKAEE--YIKLSEFY------------------EEYLDELREIEKRLS 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  479 RLQHELSRVRQEAASMAKKNSEeqvaalqklhAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQE 558
Cdd:PRK03918   318 RLEEEINGIEERIKELEEKEER----------LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  559 SLALEELELQKKAilTESENKLQELGQEAEAYRTRILELETSLEKsLQESKT------------QSEHLAVHLEAEKNKH 626
Cdd:PRK03918   388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEE-LKKAKGkcpvcgrelteeHRKELLEEYTAELKRI 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  627 NKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFqahiqdmnEKTLEKLDK 706
Cdd:PRK03918   465 EKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEY--------EKLKEKLIK 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  707 KQMELESVSSELSEalrardqlAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSrl 786
Cdd:PRK03918   537 LKGEIKSLKKELEK--------LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLE-- 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  787 gaLLDERDEhLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGayEEQLAQMQQKVLDLETEKSLLTKQ 866
Cdd:PRK03918   607 --LKDAEKE-LEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAE 681

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198992  867 VVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREE 940
Cdd:PRK03918   682 LEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEE 755
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 626-1254 7.59e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.38  E-value: 7.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  626 HNKELTALAEQHRTEVEGLQQQQDSLWTERLQ-SLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKL 704
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTKLQQEFNTLESAELRlSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELN 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  705 DKKQMELESVSSELSEALRARDQ----LAEELSVLRGDADKMKQaLEAELEEQRRHHQREVGSISEQQELTVRRaEKALK 780
Cdd:pfam12128  308 GELSAADAAVAKDRSELEALEDQhgafLDADIETAAADQEQLPS-WQSELENLEERLKALTGKHQDVTAKYNRR-RSKIK 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  781 DELSRLGALLDERDEHLRERQARVQDL-EAHLQKSAGELQqalaklDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETE 859
Cdd:pfam12128  386 EQNNRDIAGIKDKLAKIREARDRQLAVaEDDLQALESELR------EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATAT 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  860 KSLLTKQVVEMEThKKHVCEELDAQRAQVQQLERQRSELeekvRSLAQLQDSQLKNSTVEKEQARQSLMEKE-------- 931
Cdd:pfam12128  460 PELLLQLENFDER-IERAREEQEAANAEVERLQSELRQA----RKRRDQASEALRQASRRLEERQSALDELElqlfpqag 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  932 NIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVL- 1010
Cdd:pfam12128  535 TLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALq 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1011 -----------ELSQKEKQFNAQILEMAQANSA--GISDTVSRLEENQRQ---QIESLTGAHQRKLDDVIEAWEKKLSQQ 1074
Cdd:pfam12128  615 sarekqaaaeeQLVQANGELEKASREETFARTAlkNARLDLRRLFDEKQSekdKKNKALAERKDSANERLNSLEAQLKQL 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1075 AAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEEltkEVARLKEAVSGQDVALAGLQGQLEQKSA-----------VIV 1143
Cdd:pfam12128  695 DKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDA---QLALLKAAIAARRSGAKAELKALETWYKrdlaslgvdpdVIA 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1144 SLSERESQLQSQVEKLEADLGCSLSEKLSLQEE--LAELKLLADKSQLR--VSELTGQVQAAEKELQSCKSLHELSKKSL 1219
Cdd:pfam12128  772 KLKREIRTLERKIERIAVRRQEVLRYFDWYQETwlQRRPRLATQLSNIEraISELQQQLARLIADTKLRRAKLEMERKAS 851

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1907198992 1220 EDkslnLKSLLEELASQLDSRCERTKALLEAKTNE 1254
Cdd:pfam12128  852 EK----QQVRLSENLRGLRCEMSKLATLKEDANSE 882
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 839-1077 7.96e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 7.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  839 AGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNST 917
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALeAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  918 VEKEQARQSLMEKENIILQMREEQAKEIEILkqtLSSKEESISILHEEYETKF-KNQEKRMEKIKQKAKEMQETKKKLLD 996
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALL---LSPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  997 QEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgisdtvsrlEENQRQQIESLTGAhQRKLDDVIEAWEKKLSQQAA 1076
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKE---------LAELAAELAELQQE-AEELEALIARLEAEAAAAAE 241


                   .
gi 1907198992 1077 E 1077
Cdd:COG4942    242 R 242
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 727-1358 1.38e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.74  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  727 QLAEELSVLRGDADKMKQALEAELEEQRRHHQ--REVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARV 804
Cdd:TIGR00618  230 HLREALQQTQQSHAYLTQKREAQEEQLKKQQLlkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  805 QDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAyeEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQ 884
Cdd:TIGR00618  310 QRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRL--LQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  885 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQArqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHE 964
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQL---AHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQES 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  965 EYETK-FKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnAQILEMAQANSAGISDTVSRLEE 1043
Cdd:TIGR00618  465 AQSLKeREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQD--IDNPGPLTRRMQRGEQTYAQLET 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1044 ----------NQRQQIESLTGAHQRKLDDVIEAWEK---------KLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQ 1104
Cdd:TIGR00618  543 seedvyhqltSERKQRASLKEQMQEIQQSFSILTQCdnrskedipNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQ 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1105 SE--KEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEAdlgcsLSEKLSLQEELAELKL 1182
Cdd:TIGR00618  623 PEqdLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLA-----LQKMQSEKEQLTYWKE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1183 LADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCtsrdk 1262
Cdd:TIGR00618  698 MLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTA----- 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1263 ADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQ--------LTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1334
Cdd:TIGR00618  773 ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQeipsdediLNLQCETLVQEEEQFLSRLEEKSATLGEITHQLL 852

                          650       660
                   ....*....|....*....|....
gi 1907198992 1335 GLLTEKEALQQEGGQQRQAASEKE 1358
Cdd:TIGR00618  853 KYEECSKQLAQLTQEQAKIIQLSD 876
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2188-2227 1.58e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.88  E-value: 1.58e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907198992 2188 TEFEYLRKVMFEYMMGRET---KTMAKVITTVLKFPDDQAQKI 2227
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 964-1163 1.73e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  964 EEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgISDTVSRLEE 1043
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE-IAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1044 NQRQQIESLTGAHQRKLDDVIE---------------AWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKE 1108
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLAlllspedfldavrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992 1109 ELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADL 1163
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
771-1385 2.63e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  771 TVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQ 850
Cdd:COG4913    236 DLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  851 QKVLDLETEKSLLTKQvvemetHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLqdsqLKNSTVEKEQARQSLmek 930
Cdd:COG4913    316 ARLDALREELDELEAQ------IRGNGGDRLEQLEREIERLERELEERERRRARLEAL----LAALGLPLPASAEEF--- 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  931 eniilqmrEEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEnTVL 1010
Cdd:COG4913    383 --------AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALA-EAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1011 ELSQKEKQFNAQILEmaqansagisdtVSRLEENQRQQIESLTGAH-------QRKLDDVIEA-----WEKKLSQQAAEL 1078
Cdd:COG4913    454 GLDEAELPFVGELIE------------VRPEEERWRGAIERVLGGFaltllvpPEHYAAALRWvnrlhLRGRLVYERVRT 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1079 RDKHAEQMEEKEQGLGElrqKVRIVQSE-----KEELTKEVARLK----EAVSGQDVALAgLQGQLEQKSAV----IVSL 1145
Cdd:COG4913    522 GLPDPERPRLDPDSLAG---KLDFKPHPfrawlEAELGRRFDYVCvdspEELRRHPRAIT-RAGQVKGNGTRhekdDRRR 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1146 SERESQL-QSQVEKLEAdlgcslseklsLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSkksleDKSL 1224
Cdd:COG4913    598 IRSRYVLgFDNRAKLAA-----------LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYS-----WDEI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1225 NLKSLLEELASqldsrcertkalLEAKTNELvctsrDKADAILARLSQcqrhtatvgeallrrmgQVSELEAQLTQLTEE 1304
Cdd:COG4913    662 DVASAEREIAE------------LEAELERL-----DASSDDLAALEE-----------------QLEELEAELEELEEE 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1305 QRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSE 1384
Cdd:COG4913    708 LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEE 787


                   .
gi 1907198992 1385 K 1385
Cdd:COG4913    788 E 788
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 336-922 2.68e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.73  E-value: 2.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  336 MLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITEtkrqmletLELKEDEIAQLRSH 415
Cdd:pfam15921  261 LLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQ--------LSDLESTVSQLRSE 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  416 IKQMTTQGEELREQKEKSERAAFEELEKALStaQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRV---RQEAA 492
Cdd:pfam15921  333 LREAKRMYEDKIEELEKQLVLANSELTEART--ERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRlwdRDTGN 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  493 SMA----KKNSEEQVAALQKLHAEELASKEQ---ELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEEL 565
Cdd:pfam15921  411 SITidhlRRELDDRNMEVQRLEALLKAMKSEcqgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMT 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  566 ELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQE---SKTQSEHLAvHLEAEKNKHNKELTalaeQHRTEVE 642
Cdd:pfam15921  491 LESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQElqhLKNEGDHLR-NVQTECEALKLQMA----EKDKVIE 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  643 GLQQQQDSLwterLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSEL---- 718
Cdd:pfam15921  566 ILRQQIENM----TQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLvnag 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  719 SEALRA-------RDQLAEELSVLRGDADKMKQALEAeleeqrrhHQREVGSISEQQELTVRRAEKALKDELSRLgalld 791
Cdd:pfam15921  642 SERLRAvkdikqeRDQLLNEVKTSRNELNSLSEDYEV--------LKRNFRNKSEEMETTTNKLKMQLKSAQSEL----- 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  792 erdEHLRERQARVQDLEAHLQKSA-GELQQALAKLDLLHSEQSAAReqagAYEEQLAQMQQKVLDLETEKSLLTKQVVEM 870
Cdd:pfam15921  709 ---EQTRNTLKSMEGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQ----FLEEAMTNANKEKHFLKEEKNKLSQELSTV 781

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907198992  871 ETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSlAQLQDSQLKNSTVEKEQ 922
Cdd:pfam15921  782 ATEKNKMAGELEVLRSQERRLKEKVANMEVALDK-ASLQFAECQDIIQRQEQ 832
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 662-1021 4.20e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.97  E-value: 4.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  662 QHQAAVEElreKYQQEKdallkeKESLFQAHIQDMNEKTLEKLDKKQmelesvssELSEALRARDQLAEELSVLRGDADK 741
Cdd:pfam17380  279 QHQKAVSE---RQQQEK------FEKMEQERLRQEKEEKAREVERRR--------KLEEAEKARQAEMDRQAAIYAEQER 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  742 MKQALEAELEEQRRHHQREVGSISEQQELTVrraEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQA 821
Cdd:pfam17380  342 MAMERERELERIRQEERKRELERIRQEEIAM---EISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQ 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  822 LAKLDLLHSEQSAAReqagayeeqlaqmQQKVLDLETEKSLLTKQVVEMETHKKHVCEELdaqRAQVQQLERQRSELEEK 901
Cdd:pfam17380  419 KVEMEQIRAEQEEAR-------------QREVRRLEEERAREMERVRLEEQERQQQVERL---RQQEEERKRKKLELEKE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  902 VRSLAQLQDSQLKNSTVEKEQARQSLMEKENiilqMREEQAKEIeilkqtlsskEESISILHEEYETKFKNQEKRMEKIK 981
Cdd:pfam17380  483 KRDRKRAEEQRRKILEKELEERKQAMIEEER----KRKLLEKEM----------EERQKAIYEEERRREAEEERRKQQEM 548

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1907198992  982 QKAKEMQETKKKLLDQEAKL-----KKELENTVLELSQKEKQFNA 1021
Cdd:pfam17380  549 EERRRIQEQMRKATEERSRLeamerEREMMRQIVESEKARAEYEA 593
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
771-1255 4.84e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 4.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  771 TVRRAEKALKDELSRLG---ALLDERDEHLRERQARVQDLEAHLQKSAGELQQA---LAKLDLLHSEQSAAREQAGAYEE 844
Cdd:PRK03918   173 EIKRRIERLEKFIKRTEnieELIKEKEKELEEVLREINEISSELPELREELEKLekeVKELEELKEEIEELEKELESLEG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  845 QLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVcEELDAQRAQVQQLERQRSELEEKVRSLAQLQD--SQLKNSTVEKEQ 922
Cdd:PRK03918   253 SKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYIKLSEFYEEYLDELREIEKRLSrlEEEINGIEERIK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  923 ARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK 1002
Cdd:PRK03918   332 ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKIT 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1003 KELENTVLELSQKEKQFNA---------------------QILEMAQANSAGISDTVSRLEENQRQQIESLTGAH----- 1056
Cdd:PRK03918   412 ARIGELKKEIKELKKAIEElkkakgkcpvcgrelteehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEkvlkk 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1057 ------QRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSE---KEELTKEVARLKEAVSGQDVA 1127
Cdd:PRK03918   492 eselikLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKElekLEELKKKLAELEKKLDELEEE 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1128 LAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQS 1207
Cdd:PRK03918   572 LAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907198992 1208 CKSL-----HELSKKSLEDKSLNLKSLLEELaSQLDSRCERTKALLEAKTNEL 1255
Cdd:PRK03918   652 LEKKyseeeYEELREEYLELSRELAGLRAEL-EELEKRREEIKKTLEKLKEEL 703
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
969-1570 4.97e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 4.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  969 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnaqilemaqansagisdtVSRLEENQRQQ 1048
Cdd:PRK03918   159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLRE-------------------INEISSELPEL 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1049 IESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKeqgLGELRQKVRIVQSEKEELTKEVARLKEaVSGQDVAL 1128
Cdd:PRK03918   220 REELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEK---IRELEERIEELKKEIEELEEKVKELKE-LKEKAEEY 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1129 AGLQGQLEQKSAVIVSLSERESQLQSQVEKLEAdlgcSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSC 1208
Cdd:PRK03918   296 IKLSEFYEEYLDELREIEKRLSRLEEEINGIEE----RIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKK 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1209 KSLHELSKKSLEDKSLNLKSLLEELasqldsrcERTKALLEAKTNElvctsrdkadaILARLSQCQRHTATVGEALLRRM 1288
Cdd:PRK03918   372 EELERLKKRLTGLTPEKLEKELEEL--------EKAKEEIEEEISK-----------ITARIGELKKEIKELKKAIEELK 432

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1289 GQVSELEAQLTQLTEEQRtlKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEscITQLKKEL 1368
Cdd:PRK03918   433 KAKGKCPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKE--LAEQLKEL 508

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1369 AENINAVTLlrEELSEKKSEIASLSKQLSDLGAQLESSispSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEK 1448
Cdd:PRK03918   509 EEKLKKYNL--EELEKKAEEYEKLKEKLIKLKGEIKSL---KKELEKLEELKKKLAELEKKLDELEEELAELLKELEELG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1449 MSALEQVDHWSNKFSEWKKKaQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRK-S 1527
Cdd:PRK03918   584 FESVEELEERLKELEPFYNE-YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyE 662

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907198992 1528 KMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKN 1570
Cdd:PRK03918   663 ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 668-1454 5.17e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.81  E-value: 5.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  668 EELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELES---VSSELSEALRARDQLAEELSVLRGDADKMKQ 744
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEyllYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  745 ALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGAL-LDERDEHLRERQARVQDLEAHLQKSAGELQQALA 823
Cdd:pfam02463  259 EIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLkLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  824 KLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVR 903
Cdd:pfam02463  339 ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  904 SLAQLqdsqLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQK 983
Cdd:pfam02463  419 DLLKE----EKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQK 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  984 AKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRK---- 1059
Cdd:pfam02463  495 LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALtelp 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1060 ---------LDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAG 1130
Cdd:pfam02463  575 lgarklrllIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1131 LQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKS 1210
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1211 LHEL--------SKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTATVGE 1282
Cdd:pfam02463  735 NEELkllkqkidEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1283 ALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ--RQAASEKESC 1360
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQklKDELESKEEK 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1361 ITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLK 1440
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGK 974

                          810
                   ....*....|....
gi 1907198992 1441 VDALSKEKMSALEQ 1454
Cdd:pfam02463  975 VNLMAIEEFEEKEE 988
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 921-1064 6.44e-05

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 48.12  E-value: 6.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  921 EQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAK 1000
Cdd:pfam10168  553 DLAREEIQKRVKLLKLQKEQQLQELQSLEEERKSLSERAEKLAEKYEEIKDKQEKLMRRCKKVLQRLNSQLPVLSDAERE 632

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198992 1001 LKKELE--NTVLE-----LSQKEKQFNAQILEMAQANSAGISDTVSrLEENQRQQIESLTGAHQRKLDDVI 1064
Cdd:pfam10168  633 MKKELEtiNEQLKhlanaIKQAKKKMNYQRYQIAKSQSIRKKSSLS-LSEKQRKTIKEILKQLGSEIDELI 702
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
712-909 6.45e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 6.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  712 ESVSSELSEALRARDQLAEELSVLRGDADkmkqALEAELEEQRRHHQreVGSISEQQELTVRRaekalkdeLSRLGALLD 791
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELE----EAEAALEEFRQKNG--LVDLSEEAKLLLQQ--------LSELESQLA 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  792 ERDEHLRERQARVQDLEAHLQKSAGE---------LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSL 862
Cdd:COG3206    230 EARAELAEAEARLAALRAQLGSGPDAlpellqspvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQ 309

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198992  863 LTKQVVEMETHkkhvceELDAQRAQVQQLERQRSELEEKVRSLAQLQ 909
Cdd:COG3206    310 EAQRILASLEA------ELEALQAREASLQAQLAQLEARLAELPELE 350
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 275-977 6.47e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.43  E-value: 6.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  275 ISVLQTQVSLLKQRLQNGPMNVDAPKPLPPGELQAEVHGDTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRCKET 354
Cdd:TIGR00618  196 AELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQ 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  355 IGSHKE-QCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQM--LETLELKEDEIAQLRSHIKQMTTQGEELREQKE 431
Cdd:TIGR00618  276 EAVLEEtQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMrsRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEI 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  432 KSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQmkaverASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHA 511
Cdd:TIGR00618  356 HIRDAHEVATSIREISCQQHTLTQHIHTLQQQKT------TLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHA 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  512 EELASKEQELSRRLEARERElQEQMRIALEKSRSEYLKLTQEKEQQESLALEELElQKKAILTESENKLQELGQEAEAYR 591
Cdd:TIGR00618  430 KKQQELQQRYAELCAAAITC-TAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHL-QETRKKAVVLARLLELQEEPCPLC 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  592 TRILELETSLEKSLQESKTQSEHLAvhLEAEKNKHNKELTALAEQHRTEVEGLQ--QQQDSLWTERLQSLSQQHQAAVEE 669
Cdd:TIGR00618  508 GSCIHPNPARQDIDNPGPLTRRMQR--GEQTYAQLETSEEDVYHQLTSERKQRAslKEQMQEIQQSFSILTQCDNRSKED 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  670 LrEKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK--------KQMELESVSSELSEALRARDQLAEELSvlrgdADK 741
Cdd:TIGR00618  586 I-PNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLqpeqdlqdVRLHLQQCSQELALKLTALHALQLTLT-----QER 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  742 MKQALEAELEEQRRHHQREVGSISEQQELtvRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQA 821
Cdd:TIGR00618  660 VREHALSIRVLPKELLASRQLALQKMQSE--KEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  822 LAKLDllHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMETHKKHVCEELDAQRAQVQQLERQRSELEEK 901
Cdd:TIGR00618  738 EDALN--QSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGA----ELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE 811

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198992  902 VRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRM 977
Cdd:TIGR00618  812 IPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1463-2160 6.77e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.43  E-value: 6.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1463 SEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKeeqicllKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALkt 1542
Cdd:pfam02463  175 LKKLIEETENLAELIIDLEELKLQELKLKEQAKKA-------LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL-- 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1543 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKdNKVREAEETVLRLREHVSSLEAELG 1622
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK-SELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1623 TVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEK--TQRYAKDTENRLSELSAQL 1700
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESerLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1701 KEREKQVHSLEDKL-----KNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRL 1775
Cdd:pfam02463  405 KEAQLLLELARQLEdllkeEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1776 EQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVsqPMGEETGNNTGVKQNWASVVDSVQ 1855
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAV--ENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1856 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYE-KSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNV 1934
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1935 GTVDGLR--SDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 2012
Cdd:pfam02463  643 AKESGLRkgVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2013 LMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTD 2092
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992 2093 LQTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEK 2160
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
664-811 7.60e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.93  E-value: 7.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  664 QAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEElsvlrgdadkmk 743
Cdd:COG2433    379 EEALEELIEKELPEEEPEAEREKEHEERELTEEEEE-IRRLEEQVERLEAEVEELEAELEEKDERIER------------ 445

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992  744 qaLEAELEEQRRhhqrevgsiSEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHL 811
Cdd:COG2433    446 --LERELSEARS---------EERREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELW 502
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
436-909 7.92e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 7.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  436 AAFEELEKALSTAQKTEDAQRRMKMEMDEqmkaveraSEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELA 515
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEELEE--------LEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  516 SKEQELsRRLEARERELQEQMRiALEKSRSEYlkltQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRIL 595
Cdd:COG4717    143 ELPERL-EELEERLEELRELEE-ELEELEAEL----AELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  596 ELETSLEkSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQ 675
Cdd:COG4717    217 EAQEELE-ELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAR 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  676 QEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSseLSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRR 755
Cdd:COG4717    296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLS--PEELLELLDRIEELQELLREAEELEEELQLEELEQEIA 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  756 HHQREVGSISEqqeltvrraekalkDELSRLGalldERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDL--LHSEQS 833
Cdd:COG4717    374 ALLAEAGVEDE--------------EELRAAL----EQAEEYQELKEELEELEEQLEELLGELEELLEALDEeeLEEELE 435

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907198992  834 AAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQvvemethkkhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQ 909
Cdd:COG4717    436 ELEEELEELEEELEELREELAELEAELEQLEED------------GELAELLQELEELKAELRELAEEWAALKLAL 499
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
777-1064 8.04e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.20  E-value: 8.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  777 KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 856
Cdd:COG4372     48 EQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  857 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQ-DSQLKNSTVEKEQARQSLMEKENIIL 935
Cdd:COG4372    128 EQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEaEQALDELLKEANRNAEKEEELAEAEK 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  936 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQK 1015
Cdd:COG4372    208 LIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEA 287

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1907198992 1016 EKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVI 1064
Cdd:COG4372    288 LEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILL 336
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
372-799 8.47e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 8.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  372 LQEQLDERLQELEKMKGMVIT------ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKE--KSERAAFEELEK 443
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPElnlkelKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEelREELEKLEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  444 ALSTAQKTEDAQRRMKmEMDEQMKAVERAsEEERLRLQHELSRVRQEAASMAKK--NSEEQVAALQKLHAEELASKEQEL 521
Cdd:COG4717    127 LLPLYQELEALEAELA-ELPERLEELEER-LEELRELEEELEELEAELAELQEEleELLEQLSLATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  522 SRRLEARERELQEQmRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAIL---------------------------- 573
Cdd:COG4717    205 QQRLAELEEELEEA-QEELEELEEELEQLENELEAAALEERLKEARLLLLIAaallallglggsllsliltiagvlflvl 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  574 --------------TESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRT 639
Cdd:COG4717    284 gllallflllarekASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  640 EVEGLQQQQDSLWT-------ERLQSLSQQHQAAvEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELE 712
Cdd:COG4717    364 QLEELEQEIAALLAeagvedeEELRAALEQAEEY-QELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELE 442

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  713 SVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDElsRLGALLDE 792
Cdd:COG4717    443 ELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE--RLPPVLER 520


                   ....*..
gi 1907198992  793 RDEHLRE 799
Cdd:COG4717    521 ASEYFSR 527
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1959-2170 8.61e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 8.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1959 SKEVARLQKELRALRREHQQELDILKREceQEAEEKLKQEQEDLELKhTSTLKQLMREFNTQLAQKEQELERT------V 2032
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAAL--KKEEKALLKQLAALERR-IAALARRIRALEQELAALEAELAELekeiaeL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2033 QETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARR---YEEILDAREEEMTG------KVTDLQTQLEELQKK 2103
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARREQAEElradlaELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198992 2104 YQQRLEQEESTKDSVT--ILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKNACAATVGTP 2170
Cdd:COG4942    176 LEALLAELEEERAALEalKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 710-926 9.19e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.13  E-value: 9.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  710 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQEltvrraekALKDELSRLGAL 789
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYN-ELQAELEALQAEIDKLQAEIA--------EAEAEIEERREE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  790 LDERDEHLRERQARVQDLEAHLqkSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVE 869
Cdd:COG3883     88 LGERARALYRSGGSVSYLDVLL--GSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAE 165

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907198992  870 METHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 926
Cdd:COG3883    166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1139-1370 9.64e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1139 SAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKS 1218
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1219 LEDKSLNLKSLLeeLASQLDSRCERTKALLEAKtnelvctSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQL 1298
Cdd:COG4942     99 LEAQKEELAELL--RALYRLGRQPPLALLLSPE-------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907198992 1299 TQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEgllTEKEALQQEGGQQRQAASEKESCITQLKKELAE 1370
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARLEAEAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 698-912 9.72e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  698 EKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQ---ALEAELEEQRRHHQREVGSISEQQELTVRR 774
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQelaALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  775 AEKALK-DELSRLGALLDERD-EHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAgayEEQLAQMQQK 852
Cdd:COG4942    110 LRALYRlGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL---EALLAELEEE 186

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  853 VLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQ 912
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
mukB PRK04863
chromosome partition protein MukB;
661-926 1.05e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  661 QQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALR-------ARDQLAEE 731
Cdd:PRK04863   847 VELERALADHESQEQQQRSQLeqAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRfvqqhgnALAQLEPI 926

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  732 LSVLRGDadkmkqalEAELEEQRRHHQRevgsiSEQQELTVRRAEKALKDelsrlgalLDERDEHLRERQArVQDLEAhl 811
Cdd:PRK04863   927 VSVLQSD--------PEQFEQLKQDYQQ-----AQQTQRDAKQQAFALTE--------VVQRRAHFSYEDA-AEMLAK-- 982

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  812 qksAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEME------------------- 871
Cdd:PRK04863   983 ---NSDLNEKLrQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKqelqdlgvpadsgaeerar 1059

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992  872 THKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 926
Cdd:PRK04863  1060 ARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNA 1114
PRK12704 PRK12704
phosphodiesterase; Provisional
 1955-2086 1.13e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.08  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1955 KQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNtQLAQKEQELERtvqe 2034
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK-RLLQKEENLDR---- 100

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907198992 2035 tidkaqevEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEM 2086
Cdd:PRK12704   101 --------KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 444-669 1.38e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  444 ALSTAQKTEDAQRRMKmEMDEQMKAVER---ASEEERLRLQHELSRVRQEAASMAKK--NSEEQVAALQKLHAEeLASKE 518
Cdd:COG4942     15 AAAQADAAAEAEAELE-QLQQEIAELEKelaALKKEEKALLKQLAALERRIAALARRirALEQELAALEAELAE-LEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  519 QELSRRLEARERELQEQMRIALEKSRSEYLK--LTQEKEQQESLALEELELQKKAILTESEnKLQELGQEAEAYRTRILE 596
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYRLGRQPPLAllLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907198992  597 LETSLEKSLQESKTQSEHLAVhLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVEE 669
Cdd:COG4942    172 ERAELEALLAELEEERAALEA-LKAERQKLLARLEKELAELAAELAELQQEAEEL-EALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
171-839 1.53e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  171 PSDMESEAEDAPWNSDGLSR-EQLLQRLRRMERSLS---SYRGKYSELVTAFQTLQREKKKLQGILSQSQDKSLR-RISE 245
Cdd:COG4913    220 EPDTFEAADALVEHFDDLERaHEALEDAREQIELLEpirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEaELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  246 LREELQMDQQAKKHLQDEFDACLEEKDQyisvlqtqvsLLKQRLQNGPMNVDapkplppgELQAEVHGDTEKmegvgepv 325
Cdd:COG4913    300 LRAELARLEAELERLEARLDALREELDE----------LEAQIRGNGGDRLE--------QLEREIERLERE-------- 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  326 gggtsaktLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITEtKRQMLETLELK 405
Cdd:COG4913    354 --------LEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA-LRDLRRELREL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  406 EDEIAQLRSHIKQMTTQGEELReqkekseraafEELEKALSTAQ------------KTEDAQRRMKMEM----------- 462
Cdd:COG4913    425 EAEIASLERRKSNIPARLLALR-----------DALAEALGLDEaelpfvgelievRPEEERWRGAIERvlggfaltllv 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  463 -DEQMKAVERASEEERLRLQHELSRVRQEAAsmakknSEEQVAALQKLHAEELASKEQELSRRLEAR------------E 529
Cdd:COG4913    494 pPEHYAAALRWVNRLHLRGRLVYERVRTGLP------DPERPRLDPDSLAGKLDFKPHPFRAWLEAElgrrfdyvcvdsP 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  530 REL-QEQMRIALE---KSRSEylklTQEKEQQESLALE----ELELQKKAILtesENKLQELGQEAEAYRTRILELETSL 601
Cdd:COG4913    568 EELrRHPRAITRAgqvKGNGT----RHEKDDRRRIRSRyvlgFDNRAKLAAL---EAELAELEEELAEAEERLEALEAEL 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  602 EkSLQESKTQSEHLAVHLEAEKNkhnkeltalAEQHRTEVEGLQQQQDSLWTE--RLQSLSQQHQAAVEELREkYQQEKD 679
Cdd:COG4913    641 D-ALQERREALQRLAEYSWDEID---------VASAEREIAELEAELERLDASsdDLAALEEQLEELEAELEE-LEEELD 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  680 ALLKEKESLFQAHIQdmnekTLEKLDKKQMELESVSSELSEALRARdqLAEELSVLRGDADkmKQALEAELEEQRRHHQR 759
Cdd:COG4913    710 ELKGEIGRLEKELEQ-----AEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAV--ERELRENLEERIDALRA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  760 EVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQA-RVQDLEAHLQKSAGEL-QQALAKLDLLHSEQSAARE 837
Cdd:COG4913    781 RLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRlEEDGLPEYEERFKELLnENSIEFVADLLSKLRRAIR 860


                   ..
gi 1907198992  838 QA 839
Cdd:COG4913    861 EI 862
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 715-875 1.73e-04

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 45.90  E-value: 1.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  715 SSELSEALRARDQLAEELSVLRGDAdkmkQALEAELEEQRRHHQREVGSISEQ------QELTVRRAEKALKDELSRLGA 788
Cdd:pfam09787   46 TLELEELRQERDLLREEIQKLRGQI----QQLRTELQELEAQQQEEAESSREQlqeleeQLATERSARREAEAELERLQE 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  789 LLDERDEHLRE----RQARVQDLEAHLQKSAGELQQAlaklDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLT 864
Cdd:pfam09787  122 ELRYLEEELRRskatLQSRIKDREAEIEKLRNQLTSK----SQSSSSQSELENRLHQLTETLIQKQTMLEALSTEKNSLV 197

                          170
                   ....*....|.
gi 1907198992  865 KQVVEMETHKK 875
Cdd:pfam09787  198 LQLERMEQQIK 208
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
776-1243 2.60e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 2.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  776 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQ--KV 853
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKllQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  854 LDLETEKSLLTKQVVEMETHKkhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKeni 933
Cdd:COG4717    128 LPLYQELEALEAELAELPERL----EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE--- 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  934 ilqmREEQAKEIEILKQTLSSKEESISILHEEYETkfknqekrmekiKQKAKEMQETKKKLldQEAKLKKELENTVLELS 1013
Cdd:COG4717    201 ----LEELQQRLAELEEELEEAQEELEELEEELEQ------------LENELEAAALEERL--KEARLLLLIAAALLALL 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1014 QKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGL 1093
Cdd:COG4717    263 GLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLEL 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1094 GELRQKVRIVQSEKEELTKEvARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSL 1173
Cdd:COG4717    343 LDRIEELQELLREAEELEEE-LQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907198992 1174 QEELAELKLLADKSQLR--VSELTGQVQAAEKELQSCKslHELSKKSLEDKSLNLKSLLEELASQLDSRCER 1243
Cdd:COG4717    422 LEALDEEELEEELEELEeeLEELEEELEELREELAELE--AELEQLEEDGELAELLQELEELKAELRELAEE 491
PLN02939 PLN02939
transferase, transferring glycosyl groups
 776-999 2.69e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.43  E-value: 2.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  776 EKALKDELSRLGALLDERDEHLR---ERQARVQDLEAHLQKSAGELQQALA-----------KLDLLHSEQSAAREQAGA 841
Cdd:PLN02939   165 KEALQGKINILEMRLSETDARIKlaaQEKIHVEILEEQLEKLRNELLIRGAteglcvhslskELDVLKEENMLLKDDIQF 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  842 YEEQLAQMQ---QKVLDLETEKSLLTKQVVEMEthkkhvCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSqlknSTV 918
Cdd:PLN02939   245 LKAELIEVAeteERVFKLEKERSLLDASLRELE------SKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDR----ATN 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  919 EKEQARQSLMEKENI--ILQMREEQAKE----------IEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKE 986
Cdd:PLN02939   315 QVEKAALVLDQNQDLrdKVDKLEASLKEanvskfssykVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSK 394

                          250
                   ....*....|....
gi 1907198992  987 M-QETKKKLLDQEA 999
Cdd:PLN02939   395 LkEESKKRSLEHPA 408
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 893-1718 2.90e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.32  E-value: 2.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  893 RQRSELEEKVRSLAQLQDSQLK--NSTVEKEQARQSLMEKENII---LQMREEQAKEIEILKQTLSSKEESISILHEEYE 967
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKaeSELKELEKKHQQLCEEKNALqeqLQAETELCAEAEEMRARLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  968 TKFKNQEKRMEKIKQKAKEMQETKKKL---LDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSA----------GI 1034
Cdd:pfam01576   82 SRLEEEEERSQQLQNEKKKMQQHIQDLeeqLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKlskerklleeRI 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1035 SDTVSRL--EENQRQQIESLTGAHQRKLDDV-------------IEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQK 1099
Cdd:pfam01576  162 SEFTSNLaeEEEKAKSLSKLKNKHEAMISDLeerlkkeekgrqeLEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKK 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1100 vrivqseKEELTKEVARLKEAVSGQDVALAGLQgQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSeklSLQEELAE 1179
Cdd:pfam01576  242 -------EEELQAALARLEEETAQKNNALKKIR-ELEAQISELQEDLESERAARNKAEKQRRDLGEELE---ALKTELED 310

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1180 LKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSlnlKSLLEELASQLD------SRCERTKALLEAKTN 1253
Cdd:pfam01576  311 TLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKH---TQALEELTEQLEqakrnkANLEKAKQALESENA 387

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1254 ELVCTSRDKADAILARLSQCQRHTATVGEALLRrmgqVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKE-KQIKTMK-- 1330
Cdd:pfam01576  388 ELQAELRTLQQAKQDSEHKRKKLEGQLQELQAR----LSESERQRAELAEKLSKLQSELESVSSLLNEAEgKNIKLSKdv 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1331 ADIEGLLTEKEALQQEGGQQRQAASEK----ESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESS 1406
Cdd:pfam01576  464 SSLESQLQDTQELLQEETRQKLNLSTRlrqlEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAL 543

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1407 ISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQ 1486
Cdd:pfam01576  544 EEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEE 623

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1487 LDVKATDAREKE----------EQICLLKEDLDRQNKKfecLKGEMEVRKS----------KMEKKECDLETALKTQTAR 1546
Cdd:pfam01576  624 RDRAEAEAREKEtralslaralEEALEAKEELERTNKQ---LRAEMEDLVSskddvgknvhELERSKRALEQQVEEMKTQ 700

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1547 VVELEDCVTQRKKEVESLNETLKNYNQQRDTEhsglvqrLQHLEELGEEKDNKvreaeetvlrLREHVSSLEAELGTVKK 1626
Cdd:pfam01576  701 LEELEDELQATEDAKLRLEVNMQALKAQFERD-------LQARDEQGEEKRRQ----------LVKQVRELEAELEDERK 763

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1627 ELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAeqkiaairKQLLSQMEEkTQRYAKDTENRLSELSAQLKEREKQ 1706
Cdd:pfam01576  764 QRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQL--------KKLQAQMKD-LQRELEEARASRDEILAQSKESEKK 834

                          890
                   ....*....|..
gi 1907198992 1707 VHSLEDKLKNLE 1718
Cdd:pfam01576  835 LKNLEAELLQLQ 846
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1172-1412 3.33e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1172 SLQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckslhelskKSLEDKSLNLKSLLEELASQLDSRcERTKALLEAK 1251
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQL-----------AALERRIAALARRIRALEQELAAL-EAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1252 TNELVCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLT---QLTEEQRTLKSSFQQVTNQLEEKEKQIKT 1328
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1329 MKADIEGLLTEKEALQQEggqQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSIS 1408
Cdd:COG4942    172 ERAELEALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ....
gi 1907198992 1409 PSDK 1412
Cdd:COG4942    249 AALK 252
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 709-819 3.86e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 45.84  E-value: 3.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  709 MELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEltvrrAEKALKDELSRLGA 788
Cdd:COG0542    404 MEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWE-----AEKELIEEIQELKE 478

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1907198992  789 LLDERDEHLRERQARVQDLEAHLQKSAGELQ 819
Cdd:COG0542    479 ELEQRYGKIPELEKELAELEEELAELAPLLR 509
COG5022 COG5022
Myosin heavy chain [General function prediction only];
338-938 3.92e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.84  E-value: 3.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  338 QQRVKRQENLLQRCKETIGShkeqcallLSEKEALQEQLDERLQELEKmkgmvitETKRQMLETLELKEDEIAQLRSHIK 417
Cdd:COG5022    874 AQRVELAERQLQELKIDVKS--------ISSLKLVNLELESEIIELKK-------SLSSDLIENLEFKTELIARLKKLLN 938

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  418 QMTTQGEELREQKEKSERAAFEELEKALSTAQKT-EDAQRRMKMEMDEQMKAverasEEERLRLQHELS--RVRQEAASM 494
Cdd:COG5022    939 NIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEyEDLLKKSTILVREGNKA-----NSELKNFKKELAelSKQYGALQE 1013

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  495 AKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAIL- 573
Cdd:COG5022   1014 STKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLl 1093

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  574 ---TESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKE---------LTALAEQHRTEV 641
Cdd:COG5022   1094 ktiNVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLqleldglfwEANLEALPSPPP 1173

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  642 EGLQQQ----QDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESL-FQAHIQDMNEkTLEKLDkkqmelESVSS 716
Cdd:COG5022   1174 FAALSEkrlyQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKkLISEGWVPTE-YSTSLK------GFNNL 1246

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  717 ELSEALRARDQLAEELSVLRGDADKMK-QALEAELEEQRRHHQREVGSISEQQELTVRRAEKALK--DELSRLGALLDER 793
Cdd:COG5022   1247 NKKFDTPASMSNEKLLSLLNSIDNLLSsYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKsaTEVNYNSEELDDW 1326

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  794 DehlreRQARVQDLEAHLQksagELQQALAKLDLLHSEQSAAREqagayeeqLAQMQQKVLDLETEKSLLTKQVVEMETH 873
Cdd:COG5022   1327 C-----REFEISDVDEELE----ELIQAVKVLQLLKDDLNKLDE--------LLDACYSLNPAEIQNLKSRYDPADKENN 1389

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907198992  874 -KKHVCEELDAQRAQvqqlERQRSELEEKVRSLAQLQDS--------QLKNSTVEKEQARQSLME---KENIILQMR 938
Cdd:COG5022   1390 lPKEILKKIEALLIK----QELQLSLEGKDETEVHLSEIfseeksliSLDRNSIYKEEVLSSLSAlltKEKIALLDR 1462
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1931-2122 3.93e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1931 QSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTL 2010
Cdd:COG3206    204 KNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELS 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2011 KQL------MREFNTQLAQKEQELERTVQETIDKAqEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEIldAREe 2084
Cdd:COG3206    284 ARYtpnhpdVIALRAQIAALRAQLQQEAQRILASL-EAELEALQAREASLQAQLAQLEARLAELPELEAELRRL--ERE- 359

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1907198992 2085 emtgkVTDLQTQLEELQKKYQQRLEQEESTKDSVTILE 2122
Cdd:COG3206    360 -----VEVARELYESLLQRLEEARLAEALTVGNVRVID 392
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1228-1404 4.14e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1228 SLLEELASQLDS-RCERTKALLEAKTNELvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELE-AQLTQLTEEQ 1305
Cdd:COG4913    272 AELEYLRAALRLwFAQRRLELLEAELEEL----RAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREI 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1306 RTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitQLKKELAENINAVTLLREELSEK 1385
Cdd:COG4913    348 ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE---ALEEALAEAEAALRDLRRELREL 424

                          170
                   ....*....|....*....
gi 1907198992 1386 KSEIASLSKQLSDLGAQLE 1404
Cdd:COG4913    425 EAEIASLERRKSNIPARLL 443
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1956-2157 5.62e-04

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 45.07  E-value: 5.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1956 QKLSKEVARLQKELRALR---REHQQELDILKRECEQEAEEKLKQ-EQEDLE-----LKHTSTLKQLMREFNTQLAQKEQ 2026
Cdd:COG0497    161 REAYRAWRALKKELEELRadeAERARELDLLRFQLEELEAAALQPgEEEELEeerrrLSNAEKLREALQEALEALSGGEG 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2027 ELERTVQETIDKAQEVE---------AELLESHQEETQqlhrkiaekedDLRRTARRYEEILDAREEEMTgKVTDLQTQL 2097
Cdd:COG0497    241 GALDLLGQALRALERLAeydpslaelAERLESALIELE-----------EAASELRRYLDSLEFDPERLE-EVEERLALL 308

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2098 EELQKKYQQRLEQeestkdsvtILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKR 2157
Cdd:COG0497    309 RRLARKYGVTVEE---------LLAYAEELRAELAELENSDERLEELEAELAEAEAELLE 359
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1535-2077 6.02e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 6.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1535 DLETALKTQTArvvELEDCVTQRKKEVESLNETlknynQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHV 1614
Cdd:PRK02224   210 GLESELAELDE---EIERYEEQREQARETRDEA-----DEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEV 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1615 SSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIrKQLLSQMEEKTQRyAKDTENRLS 1694
Cdd:PRK02224   282 RDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAA-QAHNEEAESLRED-ADDLEERAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1695 ELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQeaPDSQDCTHKACKERLCMLQRRLSEKEKLLRR 1774
Cdd:PRK02224   360 ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD--LGNAEDFLEELREERDELREREAELEATLRT 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1775 LEQGEGEARPSQPEaqhralsGKldCTRARQ-LEDHVLIGCLPEELEEKMKCSLIVSQPmgEETGNNTGVKQNWASVVDS 1853
Cdd:PRK02224   438 ARERVEEAEALLEA-------GK--CPECGQpVEGSPHVETIEEDRERVEELEAELEDL--EEEVEEVEERLERAEDLVE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1854 VQKTLQEKELTCQALEQRVKElesdlvrergaHRLEVEKLTLKYEKSQSSQQEMDGEnkCVEVLEDRPEENSQSHEIQSN 1933
Cdd:PRK02224   507 AEDRIERLEERREDLEELIAE-----------RRETIEEKRERAEELRERAAELEAE--AEEKREAAAEAEEEAEEAREE 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1934 VGTVDGLRSDLESKLTGAERDKQKLSK-EVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 2012
Cdd:PRK02224   574 VAELNSKLAELKERIESLERIRTLLAAiADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEARE 653

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907198992 2013 LMREFNTQLAQKEQELERTVQETIDKAQEVEAelLESHQEETQQLHRKIAEKEDDLRRTARRYEE 2077
Cdd:PRK02224   654 DKERAEEYLEQVEEKLDELREERDDLQAEIGA--VENELEELEELRERREALENRVEALEALYDE 716
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 817-1035 7.04e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 7.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  817 ELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 896
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  897 ELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKR 976
Cdd:COG3883     97 RSGGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198992  977 MEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGIS 1035
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
PRK09039 PRK09039
peptidoglycan -binding protein;
1096-1237 7.18e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.19  E-value: 7.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1096 LRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQE 1175
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907198992 1176 ELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKslEDKSLNLKslLEELASQL 1237
Cdd:PRK09039   124 ELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEK--RDRESQAK--IADLGRRL 181
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 971-1207 8.34e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  971 KNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnaqiLEMAQANSAGISDTVSRLEENQRQQIE 1050
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR-----IRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1051 SLTgAHQRKLDDVIEAWEKKLSQQAAELRdKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAG 1130
Cdd:COG4942     98 ELE-AQKEELAELLRALYRLGRQPPLALL-LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907198992 1131 LQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGcslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQS 1207
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELA-------ELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
mukB PRK04863
chromosome partition protein MukB;
718-1177 8.89e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 8.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  718 LSEALRARDQLAEELSVLRGDADKMKQALEAEL----------EEQRRHHQREVGSIseQQELTvrRAEKALKDELSRLG 787
Cdd:PRK04863   235 MEAALRENRMTLEAIRVTQSDRDLFKHLITESTnyvaadymrhANERRVHLEEALEL--RRELY--TSRRQLAAEQYRLV 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  788 ALLDERDEHLRERQARVQDLEA---HL---------QKSAGELQQALAKLDLLHSEQSAAREQAgayeeqlaqmQQKVLD 855
Cdd:PRK04863   311 EMARELAELNEAESDLEQDYQAasdHLnlvqtalrqQEKIERYQADLEELEERLEEQNEVVEEA----------DEQQEE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  856 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLeRQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIIL 935
Cdd:PRK04863   381 NEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQY-QQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  936 QmreeqakeieiLKQTLSSKEESISILHEEYETKFK-NQEKRMEKIKQKAKEM---QETKKKLLDQEAKLKKELEntvlE 1011
Cdd:PRK04863   460 S-----------LEQKLSVAQAAHSQFEQAYQLVRKiAGEVSRSEAWDVARELlrrLREQRHLAEQLQQLRMRLS----E 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1012 LSQKEKQFNAQILEMAQANSagisdtVSRLEENQRQQIESLTGAHQRKLDDvieawekkLSQQAAELRDKHAEQMEEKEQ 1091
Cdd:PRK04863   525 LEQRLRQQQRAERLLAEFCK------RLGKNLDDEDELEQLQEELEARLES--------LSESVSEARERRMALRQQLEQ 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1092 gLGELRQKVRIVQSEKEELTKEVARLKEAV-----SGQDVaLAGLQGQLEQKSAVIVS---LSERESQLQSQVEKLEADL 1163
Cdd:PRK04863   591 -LQARIQRLAARAPAWLAAQDALARLREQSgeefeDSQDV-TEYMQQLLERERELTVErdeLAARKQALDEEIERLSQPG 668

                          490
                   ....*....|....
gi 1907198992 1164 GCSLSEKLSLQEEL 1177
Cdd:PRK04863   669 GSEDPRLNALAERF 682
COG5022 COG5022
Myosin heavy chain [General function prediction only];
838-1389 9.65e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.68  E-value: 9.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  838 QAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQ----VQQLERQRSELEEKVRSLAQL--QDS 911
Cdd:COG5022    823 QKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQsaqrVELAERQLQELKIDVKSISSLklVNL 902

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  912 QLKNSTVEKEQARQSLMEKENIILQ---------------------MREEQAKEIEIL--KQTLSSKEESISILHEEYET 968
Cdd:COG5022    903 ELESEIIELKKSLSSDLIENLEFKTeliarlkkllnnidleegpsiEYVKLPELNKLHevESKLKETSEEYEDLLKKSTI 982

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  969 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK--KELENTVLELSQKEKQFNAQILEMAQANSagISDTVSRLEENQR 1046
Cdd:COG5022    983 LVREGNKANSELKNFKKELAELSKQYGALQESTKqlKELPVEVAELQSASKIISSESTELSILKP--LQKLKGLLLLENN 1060

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1047 QQIESLTGAHQRKLDDVI-----------EAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVA 1115
Cdd:COG5022   1061 QLQARYKALKLRRENSLLddkqlyqlestENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVN 1140

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1116 RLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEEL-AELKLLADKS------Q 1188
Cdd:COG5022   1141 TLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLkNELIALFSKIfsgwprG 1220

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1189 LRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRC--ERTKALLEAKTNELVCTSRDKADAI 1266
Cdd:COG5022   1221 DKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSsyKLEEEVLPATINSLLQYINVGLFNA 1300

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1267 LArlSQCQRHTATVGEAL----------LRRMGqVSELEAQLTQLTEEQRTLkssfQQVTNQLEEKEKQIKTMK----AD 1332
Cdd:COG5022   1301 LR--TKASSLRWKSATEVnynseelddwCREFE-ISDVDEELEELIQAVKVL----QLLKDDLNKLDELLDACYslnpAE 1373

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198992 1333 IEGLLTEKEALQQEGG--QQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEI 1389
Cdd:COG5022   1374 IQNLKSRYDPADKENNlpKEILKKIEALLIKQELQLSLEGKDETEVHLSEIFSEEKSLI 1432
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1078-1321 1.08e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1078 LRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKeavsgQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1157
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELA 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1158 KLEADLgcslsEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQsckslhELSKKSLED--KSLNLKSLLEELAS 1235
Cdd:COG3206    237 EAEARL-----AALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELA------ELSARYTPNhpDVIALRAQIAALRA 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1236 QLDSRCERTKALLEAKTNELvctsRDKADAILARLSQcqrhtatvgeaLLRRMGQVSELEAQLTQLTEEQRTLKSSFQQV 1315
Cdd:COG3206    306 QLQQEAQRILASLEAELEAL----QAREASLQAQLAQ-----------LEARLAELPELEAELRRLEREVEVARELYESL 370


                   ....*.
gi 1907198992 1316 TNQLEE 1321
Cdd:COG3206    371 LQRLEE 376
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 710-955 1.13e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  710 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQeltvrraeKALKDELSRLGAL 789
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQEL--------AALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  790 LDERDEHLRERQARVQDLEAHLQKSAgelQQALAKLdLLHSEQSAAREQAGAYEEQLAQMQQKVLDLetekslLTKQVVE 869
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLG---RQPPLAL-LLSPEDFLDAVRRLQYLKYLAPARREQAEE------LRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  870 METHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQdSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILK 949
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLL-ARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                   ....*.
gi 1907198992  950 QTLSSK 955
Cdd:COG4942    241 ERTPAA 246
46 PHA02562
endonuclease subunit; Provisional
 850-1089 1.15e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.85  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  850 QQKVLDLETEKSLLTKQVvemETHKKHVcEELDAQRAQ-VQQLERQRSELEEKVRSLAQLQDS---QLKNSTVEKEqarq 925
Cdd:PHA02562   180 NQQIQTLDMKIDHIQQQI---KTYNKNI-EEQRKKNGEnIARKQNKYDELVEEAKTIKAEIEEltdELLNLVMDIE---- 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  926 slmEKENIILQMREEQAKeieilkqtLSSKEESISILHEEYET---------KFKNQEKRMEKIKQKAKEMQETKKKLLD 996
Cdd:PHA02562   252 ---DPSAALNKLNTAAAK--------IKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDT 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  997 QEAKLkKELENTVLELSQKEKQFNAQIlemaQANSAGISDTVSRLEENQRqQIESLTGAHQRKLDDVieaweKKLSQQAA 1076
Cdd:PHA02562   321 AIDEL-EEIMDEFNEQSKKLLELKNKI----STNKQSLITLVDKAKKVKA-AIEELQAEFVDNAEEL-----AKLQDELD 389

                          250
                   ....*....|...
gi 1907198992 1077 ELRDKHAEQMEEK 1089
Cdd:PHA02562   390 KIVKTKSELVKEK 402
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1464-2100 1.17e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1464 EWKKKAQSRLAQHQSTIKDLQAQLDV-----KATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLET 1538
Cdd:TIGR00618  253 EEQLKKQQLLKQLRARIEELRAQEAVleetqERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1539 ALKTQTA--RVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSS 1616
Cdd:TIGR00618  333 HVKQQSSieEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHT-LTQHIHTLQQQKTTLTQKLQSLCKELDILQREQAT 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1617 LEAELGTVKKELEHVNSSvksrDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSEL 1696
Cdd:TIGR00618  412 IDTRTSAFRDLQGQLAHA----KKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETR 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1697 SAQLKEREKQVHSLEDKLKNlESSPHPEVPAVSRSMQSVAASPEQEAPDsqdcTHKACKERLCMLQRRLSEKEKLLRRLE 1776
Cdd:TIGR00618  488 KKAVVLARLLELQEEPCPLC-GSCIHPNPARQDIDNPGPLTRRMQRGEQ----TYAQLETSEEDVYHQLTSERKQRASLK 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1777 QGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVL-IGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQ 1855
Cdd:TIGR00618  563 EQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQdLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELA 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1856 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDgenkcvevLEDRPEENSQSHEIQSNVG 1935
Cdd:TIGR00618  643 LKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYW--------KEMLAQCQTLLRELETHIE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1936 TVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDIlkrECEQEAEEKLKQEQEDLELKHTSTLKQLMR 2015
Cdd:TIGR00618  715 EYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTE---AHFNNNEEVTAALQTGAELSHLAAEIQFFN 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2016 EFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDARE--EEMTGKVTDL 2093
Cdd:TIGR00618  792 RLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKqlAQLTQEQAKI 871


                   ....*..
gi 1907198992 2094 QTQLEEL 2100
Cdd:TIGR00618  872 IQLSDKL 878
Rabaptin pfam03528
Rabaptin;
374-749 1.28e-03

Rabaptin;


Pssm-ID: 367545 [Multi-domain]  Cd Length: 486  Bit Score: 43.94  E-value: 1.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  374 EQLDERLQELEKMKGmvitetkrQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEkalstAQKTED 453
Cdd:pfam03528    4 EDLQQRVAELEKENA--------EFYRLKQQLEAEFNQKRAKFKELYLAKEEDLKRQNAVLQEAQVELD-----ALQNQL 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  454 AQRRMKMEmdeQMKAVERASEEerlrlqhelsrVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEaRERELQ 533
Cdd:pfam03528   71 ALARAEME---NIKAVATVSEN-----------TKQEAIDEVKSQWQEEVASLQAIMKETVREYEVQFHRRLE-QERAQW 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  534 EQMRIALEKSRSEYLKLTQEKEQQESLaleelelqkkailtesENKLQELGQEAEAYRTRILELETSLeKSLQESKTQSE 613
Cdd:pfam03528  136 NQYRESAEREIADLRRRLSEGQEEENL----------------EDEMKKAQEDAEKLRSVVMPMEKEI-AALKAKLTEAE 198

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  614 HLAVHLEAEKNKHNKELTALAEQHRTEVE---GLQQQQDSLWTERLQSLSQQhqaaVEELREKYQQEKDALLKEKESLFQ 690
Cdd:pfam03528  199 DKIKELEASKMKELNHYLEAEKSCRTDLEmyvAVLNTQKSVLQEDAEKLRKE----LHEVCHLLEQERQQHNQLKHTWQK 274

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907198992  691 AHIQDMNEKTLEKLDKKQMELESVSSELS--EALRARDQLAEELSVLRGDADKMKQALEAE 749
Cdd:pfam03528  275 ANDQFLESQRLLMRDMQRMESVLTSEQLRqvEEIKKKDQEEHKRARTHKEKETLKSDREHT 335
PRK01156 PRK01156
chromosome segregation protein; Provisional
 818-1405 1.29e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.12  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  818 LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSE 897
Cdd:PRK01156   178 LRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  898 LEEKVRSLAQLQDSQLKNSTVEKEqarqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILheeyetkfKNQEKRM 977
Cdd:PRK01156   258 IKTAESDLSMELEKNNYYKELEER-----HMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNI--------DAEINKY 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  978 EKIKQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEKQFNAQILEMAQANsagisdtvsRLEENQRQQIESLTGAHQ 1057
Cdd:PRK01156   325 HAIIKKLSVLQKDYNDYIKKKSR-YDDLNNQILELEGYEMDYNSYLKSIESLK---------KKIEEYSKNIERMSAFIS 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1058 RKLdDVIEAWEKKLSQQAAELRDKhaeqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLkeavSGQDVA-LAGLQGQLE 1136
Cdd:PRK01156   395 EIL-KIQEIDPDAIKKELNEINVK----LQDISSKVSSLNQRIRALRENLDELSRNMEML----NGQSVCpVCGTTLGEE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1137 QKSAVIVSLSERESQLQSQVEKLEADLGcSLSEKLSLQEELAElkLLADKSQLRVSELTGQVQAAEKELQSckslHELSK 1216
Cdd:PRK01156   466 KSNHIINHYNEKKSRLEEKIREIEIEVK-DIDEKIVDLKKRKE--YLESEEINKSINEYNKIESARADLED----IKIKI 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1217 KSLEDKSLNLKSLLEELAS----QLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTAtvgEALLRRMGQVS 1292
Cdd:PRK01156   539 NELKDKHDKYEEIKNRYKSlkleDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQ---EIEIGFPDDKS 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1293 ELEAQLTQLTEEQRTLKSSFqqvtNQLEEKEKQIKTMKADIEGL---LTEKEALQQEGGQQRQAASEKESCITQLKKELA 1369
Cdd:PRK01156   616 YIDKSIREIENEANNLNNKY----NEIQENKILIEKLRGKIDNYkkqIAEIDSIIPDLKEITSRINDIEDNLKKSRKALD 691

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1907198992 1370 ENINAVTLLREELSEKKSEIASLSKQLSDLGAQLES 1405
Cdd:PRK01156   692 DAKANRARLESTIEILRTRINELSDRINDINETLES 727
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1983-2065 1.34e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.05  E-value: 1.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1983 LKRECEQEAEE--KLKQEQEDLELKhtstLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRK 2060
Cdd:PRK00409   528 LERELEQKAEEaeALLKEAEKLKEE----LEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYAS 603


                   ....*
gi 1907198992 2061 IAEKE 2065
Cdd:PRK00409   604 VKAHE 608
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1937-2134 1.40e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1937 VDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREH------QQELDILKRECE--QEAEEKLKQEQEDLE-LKHT 2007
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEeeyaelQEELEELEEELEelEAELEELREELEKLEkLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2008 STLKQLMREFNTQLAQKEQELER------TVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDA 2081
Cdd:COG4717    128 LPLYQELEALEAELAELPERLEEleerleELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907198992 2082 REEemtgkvtdLQTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLI 2134
Cdd:COG4717    208 LAE--------LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLL 252
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 342-610 1.43e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 1.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  342 KRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKR--QMLETLELKEDEIAQLRSHIKQM 419
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEieQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  420 TTQGEELREQKEKSErAAFEELEKALSTAQKT-EDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRV---------RQ 489
Cdd:TIGR02169  750 EQEIENVKSELKELE-ARIEELEEDLHKLEEAlNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIeqklnrltlEK 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  490 EAASMAKKNSEEQVAALqKLHAEELASKEQELSRRLEARERELQEqMRIALEKSRSEYLKLTQEKEQQeslaleelelqk 569
Cdd:TIGR02169  829 EYLEKEIQELQEQRIDL-KEQIKSIEKEIENLNGKKEELEEELEE-LEAALRDLESRLGDLKKERDEL------------ 894

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1907198992  570 KAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKT 610
Cdd:TIGR02169  895 EAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 778-1413 2.06e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 2.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  778 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLdllhSEQSAAREQAGAYEEQLAQMQQKVLDLE 857
Cdd:TIGR00618  198 LLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYL----TQKREAQEEQLKKQQLLKQLRARIEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  858 TEKSLLTKQ--VVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLqdsqlknstvekeqarqsLMEKENIIL 935
Cdd:TIGR00618  274 AQEAVLEETqeRINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL------------------LMKRAAHVK 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  936 QMREEQakEIEILKQTLSSKEESISILHEEyETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEntvlelsqK 1015
Cdd:TIGR00618  336 QQSSIE--EQRRLLQTLHSQEIHIRDAHEV-ATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELD--------I 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1016 EKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGE 1095
Cdd:TIGR00618  405 LQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQ 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1096 LRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLqGQLEQKSAVIVSLSERESQLQSQVEKLEADLgcslsekLSLQE 1175
Cdd:TIGR00618  485 ETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDI-DNPGPLTRRMQRGEQTYAQLETSEEDVYHQL-------TSERK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1176 ELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNEL 1255
Cdd:TIGR00618  557 QRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQ 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1256 VCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQrTLKSSFQQVTNQLEEKEKQIKTMKADIEG 1335
Cdd:TIGR00618  637 CSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQ-SEKEQLTYWKEMLAQCQTLLRELETHIEE 715

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992 1336 LLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKA 1413
Cdd:TIGR00618  716 YDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRL 793
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 607-851 2.12e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  607 ESKTQSEHLAVHLE---AEKNKHNKELTALAEQHRTEVEGlQQQQDSLWTERLQSLSQQHQAaveeLREKYQQEKDALLK 683
Cdd:NF012221  1539 ESSQQADAVSKHAKqddAAQNALADKERAEADRQRLEQEK-QQQLAAISGSQSQLESTDQNA----LETNGQAQRDAILE 1613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  684 EKESlFQAHIQDMNeKTLEKLDkkqmELESVSSELSEalRARDQLAEE-LSVLRGDADKMKQALEAELEEQRRHH---QR 759
Cdd:NF012221  1614 ESRA-VTKELTTLA-QGLDALD----SQATYAGESGD--QWRNPFAGGlLDRVQEQLDDAKKISGKQLADAKQRHvdnQQ 1685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  760 EVGSISEQQELTVRRAEKalkdelSRLGALLDERDEHlreRQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 839
Cdd:NF012221  1686 KVKDAVAKSEAGVAQGEQ------NQANAEQDIDDAK---ADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                          250
                   ....*....|..
gi 1907198992  840 GAyEEQLAQMQQ 851
Cdd:NF012221  1757 AA-ENKANQAQA 1767
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 352-1164 2.13e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.50  E-value: 2.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  352 KETIGSHKEQCALLLSEKEALQEQLDERLQ------ELEKMKGMVIT--------ETKRQMLETLELKEDEI-------- 409
Cdd:TIGR00606  151 NNVIFCHQEDSNWPLSEGKALKQKFDEIFSatryikALETLRQVRQTqgqkvqehQMELKYLKQYKEKACEIrdqitske 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  410 AQLRSHIKQMTTQGEELREQKEKSE-----RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHEL 484
Cdd:TIGR00606  231 AQLESSREIVKSYENELDPLKNRLKeiehnLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNH 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  485 SRVRQEaasmakknSEEQVAALQKlHAEELASKEQELSRR---LEARERELQEQMRIALEKSR---SEYLKLTQEKEQQE 558
Cdd:TIGR00606  311 QRTVRE--------KERELVDCQR-ELEKLNKERRLLNQEkteLLVEQGRLQLQADRHQEHIRardSLIQSLATRLELDG 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  559 SLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELtalaEQHR 638
Cdd:TIGR00606  382 FERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQ----EELK 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  639 TEVEGLQQQQDSlwTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMnEKTLEKLDKKQMELESVSSEL 718
Cdd:TIGR00606  458 FVIKELQQLEGS--SDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADL-DRKLRKLDQEMEQLNHHTTTR 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  719 SEAL--------------RARDQLAEELSVLRGDADKMKQALE---------AELEEQRRHHQREVGSiSEQQELTVRRA 775
Cdd:TIGR00606  535 TQMEmltkdkmdkdeqirKIKSRHSDELTSLLGYFPNKKQLEDwlhskskeiNQTRDRLAKLNKELAS-LEQNKNHINNE 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  776 EKALKDELSRLGALLDERDEHlRERQARVQDLEAHLQKSAGELQQALAKLDLLHS--EQSAAREQA------------GA 841
Cdd:TIGR00606  614 LESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQfiTQLTDENQSccpvcqrvfqteAE 692

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  842 YEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQlQDSQLKNSTVEKE 921
Cdd:TIGR00606  693 LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNR-DIQRLKNDIEEQE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  922 QARQSLMEKENI---------ILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEK--RMEKIKQKAKEMQet 990
Cdd:TIGR00606  772 TLLGTIMPEEESakvcltdvtIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqhELDTVVSKIELNR-- 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  991 kkKLLDQEAKLKKELENTVLELsqkeKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESltgAHQRKLDDVIEAWEKK 1070
Cdd:TIGR00606  850 --KLIQDQQEQIQHLKSKTNEL----KSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREI---KDAKEQDSPLETFLEK 920

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1071 LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARlkeavsgqdvalaGLQGQLEQKSAVIVSLSERES 1150
Cdd:TIGR00606  921 DQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQD-------------GKDDYLKQKETELNTVNAQLE 987

                          890
                   ....*....|....
gi 1907198992 1151 QLQSQVEKLEADLG 1164
Cdd:TIGR00606  988 ECEKHQEKINEDMR 1001
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 337-1336 2.17e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 2.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  337 LQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKmkgmviTETKRQMLE----TLELK----EDE 408
Cdd:pfam01576   66 LAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDE------EEAARQKLQlekvTTEAKikklEED 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  409 IAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTaQKTEDAQRRMKMEMDEQMKaverasEEERLRLQHELSRVR 488
Cdd:pfam01576  140 ILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSL-SKLKNKHEAMISDLEERLK------KEEKGRQELEKAKRK 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  489 QEAASmakKNSEEQVAALQKLHAE---ELASKEQELSRRLeARERELQEQMRIALEKSRSEYLKLTQEKEQqeslaleel 565
Cdd:pfam01576  213 LEGES---TDLQEQIAELQAQIAElraQLAKKEEELQAAL-ARLEEETAQKNNALKKIRELEAQISELQED--------- 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  566 ELQKKAILTESENKLQELGQEAEAYRTrilELETSLEKSL--QESKTQSE----HLAVHLEAEKNKHNKELTALAEQHRT 639
Cdd:pfam01576  280 LESERAARNKAEKQRRDLGEELEALKT---ELEDTLDTTAaqQELRSKREqevtELKKALEEETRSHEAQLQEMRQKHTQ 356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  640 EVEGLQQQQDSL------WTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESlfQAHIQDMNEKT----------LEK 703
Cdd:pfam01576  357 ALEELTEQLEQAkrnkanLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKL--EGQLQELQARLseserqraelAEK 434

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  704 LDKKQMELESVSSELSEALRARDQLAEELSVLrgdadkmkqaleaeleEQRRHHQREVGSISEQQELTVRRAEKALKDEL 783
Cdd:pfam01576  435 LSKLQSELESVSSLLNEAEGKNIKLSKDVSSL----------------ESQLQDTQELLQEETRQKLNLSTRLRQLEDER 498

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  784 SRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLL 863
Cdd:pfam01576  499 NSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRL 578

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  864 TKQVVEMEThkkhvceELDAQRAQVQQLERQRSEL------EEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQM 937
Cdd:pfam01576  579 QQELDDLLV-------DLDHQRQLVSNLEKKQKKFdqmlaeEKAISARYAEERDRAEAEAREKETRALSLARALEEALEA 651

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  938 REEQAKEIEILK----QTLSSKEESISILHEEYETKfKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELS 1013
Cdd:pfam01576  652 KEELERTNKQLRaemeDLVSSKDDVGKNVHELERSK-RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFE 730

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1014 QKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLD-----DVIEAWEKKLSQQAAELRDKHAeQMEE 1088
Cdd:pfam01576  731 RDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDlkeleAQIDAANKGREEAVKQLKKLQA-QMKD 809

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1089 KEQGLGELRQ-KVRIVQSEKEE------LTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEA 1161
Cdd:pfam01576  810 LQRELEEARAsRDEILAQSKESekklknLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEA 889

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1162 DLGcslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSL---HELSKKSLEDKSLNLKSLLEELASQLD 1238
Cdd:pfam01576  890 RIA-------QLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTsqkSESARQQLERQNKELKAKLQEMEGTVK 962

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1239 SRCERTKALLEAK-----------------TNELVCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQL 1301
Cdd:pfam01576  963 SKFKSSIAALEAKiaqleeqleqesrerqaANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEA 1042

                         1050      1060      1070
                   ....*....|....*....|....*....|....*
gi 1907198992 1302 TEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGL 1336
Cdd:pfam01576 1043 EEEASRANAARRKLQRELDDATESNESMNREVSTL 1077
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1922-2113 2.20e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1922 EENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-----EKLK 1996
Cdd:COG4942     38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEllralYRLG 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1997 QEQEDLELKHTSTLKQ------LMREFNTQLAQKEQELERTVQETIDKAQEVEAE------LLESHQEETQQLHRKIAEK 2064
Cdd:COG4942    118 RQPPLALLLSPEDFLDavrrlqYLKYLAPARREQAEELRADLAELAALRAELEAEraeleaLLAELEEERAALEALKAER 197

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1907198992 2065 EDDLRRTARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 2113
Cdd:COG4942    198 QKLLARLEKELAE-LAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK11281 PRK11281
mechanosensitive channel MscK;
1952-2155 2.22e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.36  E-value: 2.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1952 ERDKQKLSKEVARLQKELRalrrEHQQELDILKRECEQEAEEKL-KQEQEDLELKHTSTLKQL------MREFNTQLAQK 2024
Cdd:PRK11281    79 KEETEQLKQQLAQAPAKLR----QAQAELEALKDDNDEETRETLsTLSLRQLESRLAQTLDQLqnaqndLAEYNSQLVSL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2025 EQELERtVQETIDKA----QEVEAELLESHQEET-------QQLHRKIA--EKEDDLRRT----ARRYEEILDAREEEMT 2087
Cdd:PRK11281   155 QTQPER-AQAALYANsqrlQQIRNLLKGGKVGGKalrpsqrVLLQAEQAllNAQNDLQRKslegNTQLQDLLQKQRDYLT 233

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198992 2088 GKVTDLQTQLEELQKK-YQQRLEQEESTKDsvtilelQTQLAQKTTLISDSKLKEQELrEQVHNLEDRL 2155
Cdd:PRK11281   234 ARIQRLEHQLQLLQEAiNSKRLTLSEKTVQ-------EAQSQDEAARIQANPLVAQEL-EINLQLSQRL 294
PRK12704 PRK12704
phosphodiesterase; Provisional
 506-686 2.38e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 2.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  506 LQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQeslaleelelqkkaiLTESENKLQELGQ 585
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKE---------------LRERRNELQKLEK 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  586 eaeayrtRILELETSLEKSLQESKTQSEhlavHLEAEKNKHNKELTALAEQhRTEVEGLQQQQDslwtERLQSLSQ--QH 663
Cdd:PRK12704    90 -------RLLQKEENLDRKLELLEKREE----ELEKKEKELEQKQQELEKK-EEELEELIEEQL----QELERISGltAE 153

                          170       180
                   ....*....|....*....|....*.
gi 1907198992  664 QA---AVEELREKYQQEKDALLKEKE 686
Cdd:PRK12704   154 EAkeiLLEKVEEEARHEAAVLIKEIE 179
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1859-2172 2.59e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 2.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1859 QEKELTCQALEQRVKELESDLVRERgahrlEVEKLTLKYEKSQSSQQEMDGENKCVEvLEDRPEENSQ--SHEIQSNVGT 1936
Cdd:pfam17380  303 QEKEEKAREVERRRKLEEAEKARQA-----EMDRQAAIYAEQERMAMERERELERIR-QEERKRELERirQEEIAMEISR 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1937 VDGLRSDLESKLTGAERDKQKLskEVARLQKelrALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMRE 2016
Cdd:pfam17380  377 MRELERLQMERQQKNERVRQEL--EAARKVK---ILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERV 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2017 FNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEildaREEEMtgkvtdLQTQ 2096
Cdd:pfam17380  452 RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEE----RKRKL------LEKE 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2097 LEELQK---KYQQRLEQEESTKDSVTILE---LQTQLAQKTTLIS--DSKLKEQELREQVHNLEDRLKRYEKNACAATVG 2168
Cdd:pfam17380  522 MEERQKaiyEEERRREAEEERRKQQEMEErrrIQEQMRKATEERSrlEAMEREREMMRQIVESEKARAEYEATTPITTIK 601


                   ....
gi 1907198992 2169 TPYK 2172
Cdd:pfam17380  602 PIYR 605
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 332-928 2.61e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 43.25  E-value: 2.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  332 KTLEMLQQRVKRQENLLQRCKETigsHKEQCALLLSEKEALQEQLDERLQeLEKMKGMVITETKRQMLETLELKEDEIAQ 411
Cdd:PRK10246   233 KQLLTAQQQQQQSLNWLTRLDEL---QQEASRRQQALQQALAAEEKAQPQ-LAALSLAQPARQLRPHWERIQEQSAALAH 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  412 LRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQK------TEDAQRRMKMEMdeqmkAVERASEEERLRLQHELS 485
Cdd:PRK10246   309 TRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSlntwlaEHDRFRQWNNEL-----AGWRAQFSQQTSDREQLR 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  486 RVRQEAASMAKKNSEEQVAALQkLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEEL 565
Cdd:PRK10246   384 QWQQQLTHAEQKLNALPAITLT-LTADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  566 ELQKKAILTESENKLQELGQEAEAyRTRILELEtSLEKSLQESKT-----QSEHLAVH----LEAEKNKH-----NKELT 631
Cdd:PRK10246   463 LNEMRQRYKEKTQQLADVKTICEQ-EARIKDLE-AQRAQLQAGQPcplcgSTSHPAVEayqaLEPGVNQSrldalEKEVK 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  632 ALAEQH---RTEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQ 708
Cdd:PRK10246   541 KLGEEGaalRGQLDALTKQLQRD-ESEAQSLRQEEQALTQQWQAVCASLNITLQPQDDIQPWLDAQEEHERQLRLLSQRH 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  709 MELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTvrrAEKALKDELSRLGA 788
Cdd:PRK10246   620 ELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEASWLATRQQEAQSWQQRQN---ELTALQNRIQQLTP 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  789 LLD---ERDEHLRER------------------QARVQDLEAHLQKSAGELQQALAKLD--LLHS--EQSAAREQAGAYE 843
Cdd:PRK10246   697 LLEtlpQSDDLPHSEetvaldnwrqvheqclslHSQLQTLQQQDVLEAQRLQKAQAQFDtaLQASvfDDQQAFLAALLDE 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  844 EQLAQMQQKVLDLETE----KSLLTKQVVEMETHKKHVCEELDAQrAQVQQLERQRSELEEKVRSLAQLQD---SQLKNS 916
Cdd:PRK10246   777 ETLTQLEQLKQNLENQrqqaQTLVTQTAQALAQHQQHRPDGLDLT-VTVEQIQQELAQLAQQLRENTTRQGeirQQLKQD 855

                          650
                   ....*....|..
gi 1907198992  917 TvEKEQARQSLM 928
Cdd:PRK10246   856 A-DNRQQQQALM 866
mukB PRK04863
chromosome partition protein MukB;
474-1218 2.63e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  474 EEERLRLQHELSRVRQEAASmakknSEEQVAALQKLHaEELASKEQELSRRLEARERELQ----------EQMRI--ALE 541
Cdd:PRK04863   278 ANERRVHLEEALELRRELYT-----SRRQLAAEQYRL-VEMARELAELNEAESDLEQDYQaasdhlnlvqTALRQqeKIE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  542 KSRSEYLKLTQEKEQQESLALEELELQkkailTESENKLQELGQEAEAYRTRILELETSLEksLQESKTQSEHLAVHLEA 621
Cdd:PRK04863   352 RYQADLEELEERLEEQNEVVEEADEQQ-----EENEARAEAAEEEVDELKSQLADYQQALD--VQQTRAIQYQQAVQALE 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  622 EKNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQ---HQAAVEELREKYQ---------QEKDALLKEKESLF 689
Cdd:PRK04863   425 RAKQLCGLPDLTADNAEDWLEEFQAKEQEA-TEELLSLEQKlsvAQAAHSQFEQAYQlvrkiagevSRSEAWDVARELLR 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  690 QAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMkQALEAELEEQRRHHQREVGSISEQQE 769
Cdd:PRK04863   504 RLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDEL-EQLQEELEARLESLSESVSEARERRM 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  770 lTVRRAEKALKDELSRLGAL------LDERDEHLRE----RQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 839
Cdd:PRK04863   583 -ALRQQLEQLQARIQRLAARapawlaAQDALARLREqsgeEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEI 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  840 -------GAYEEQLAQMQQK---------------------------------VLDLETEKSLLTKQ------------- 866
Cdd:PRK04863   662 erlsqpgGSEDPRLNALAERfggvllseiyddvsledapyfsalygparhaivVPDLSDAAEQLAGLedcpedlyliegd 741

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  867 -------VVEMETHKKHVCEEL-DAQ--------------RAQVQQLERQRSELEEKVRSLAQLQ-DSQLKNSTVEK--- 920
Cdd:PRK04863   742 pdsfddsVFSVEELEKAVVVKIaDRQwrysrfpevplfgrAAREKRIEQLRAEREELAERYATLSfDVQKLQRLHQAfsr 821

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  921 ------------------EQARQSLMEKENIILQMRE------EQAKEIEILKQTLSSKEESISILHEEyetkfkNQEKR 976
Cdd:PRK04863   822 figshlavafeadpeaelRQLNRRRVELERALADHESqeqqqrSQLEQAKEGLSALNRLLPRLNLLADE------TLADR 895

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  977 MEKIKQKAKEMQETkKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgisdtvsrlEENQRQQIESLTGAH 1056
Cdd:PRK04863   896 VEEIREQLDEAEEA-KRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQT---------QRDAKQQAFALTEVV 965

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1057 QRKLDDVIEAWEKKLSqQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLE 1136
Cdd:PRK04863   966 QRRAHFSYEDAAEMLA-KNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQ 1044

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1137 QKSAVIVslSERESQLQSQVEKLEADLGCSLSEKLSLQEELAelklladKSQLRVSELTGQVQAAEKELQSCKSLHELSK 1216
Cdd:PRK04863  1045 DLGVPAD--SGAEERARARRDELHARLSANRSRRNQLEKQLT-------FCEAEMDNLTKKLRKLERDYHEMREQVVNAK 1115


                   ..
gi 1907198992 1217 KS 1218
Cdd:PRK04863  1116 AG 1117
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 191-852 2.81e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 2.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  191 EQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSQDkslrRISELREELQMDQQAKKHLQDEFDACLEE 270
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE----ELEDLRAELEEVDKEFAETRDELKDYREK 393

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  271 KDQYIS---VLQTQVSLLKQRLQNGPMNVdapkplppGELQAEVHGDTEKMEGvgepvgggtSAKTLEMLQQRVKRQENL 347
Cdd:TIGR02169  394 LEKLKReinELKRELDRLQEELQRLSEEL--------ADLNAAIAGIEAKINE---------LEEEKEDKALEIKKQEWK 456

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  348 LQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKG--MVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEE 425
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAqaRASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGER 536

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  426 LREQKE--KSERAAFEELEKALSTAQKTEDAQRRM----------KM-----------------------EMDEQMKA-- 468
Cdd:TIGR02169  537 YATAIEvaAGNRLNNVVVEDDAVAKEAIELLKRRKagratflplnKMrderrdlsilsedgvigfavdlvEFDPKYEPaf 616

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  469 ---------VERASEEERLRLQHELSRVRQE----AASMA----KKNSEEQVAALQKLHAEELASKEQELSRRLEA--RE 529
Cdd:TIGR02169  617 kyvfgdtlvVEDIEAARRLMGKYRMVTLEGElfekSGAMTggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSlqSE 696

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  530 RELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQkKAILTESENKLQELGQEAEAYRTRILELETSLEKsLQESK 609
Cdd:TIGR02169  697 LRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL-KERLEELEEDLSSLEQEIENVKSELKELEARIEE-LEEDL 774

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  610 TQSEHLAVHLEAEKNKHN-KELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKyqQEKDALLKEKESL 688
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREI-EQKLNRLTLEKEYLEKEIQEL--QEQRIDLKEQIKS 851

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  689 FQAHIQDMN---EKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadKMKQALEAELEEQRRHHQREVGSIS 765
Cdd:TIGR02169  852 IEKEIENLNgkkEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELE----RKIEELEAQIEKKRKRLSELKAKLE 927

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  766 EQQElTVRRAEKALKDELSRLGALLDERD--EHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYE 843
Cdd:TIGR02169  928 ALEE-ELSEIEDPKGEDEEIPEEELSLEDvqAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006


                   ....*....
gi 1907198992  844 EQLAQMQQK 852
Cdd:TIGR02169 1007 ERIEEYEKK 1015
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
962-1419 2.89e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  962 LHEEYETKfKNQEKRMEKIKQKAKEMQETKKKLLDQEAklkkELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRL 1041
Cdd:COG4913    240 AHEALEDA-REQIELLEPIRELAERYAAARERLAELEY----LRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1042 EENQRQQIESLTGAHQRKLD---DVIEAWEKKLSQQAAELRDK--HAEQMEEKEQGLG--------ELRQKVRIVQSEKE 1108
Cdd:COG4913    315 EARLDALREELDELEAQIRGnggDRLEQLEREIERLERELEERerRRARLEALLAALGlplpasaeEFAALRAEAAALLE 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1109 ELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLgcslSEKLSLQEelAELKLLADKSQ 1188
Cdd:COG4913    395 ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAL----AEALGLDE--AELPFVGELIE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1189 LRVSELTGQvQAAEKELQSCK------------------SLH----------ELSKKSLEDKSLNLKSLLEELASQLDSR 1240
Cdd:COG4913    469 VRPEEERWR-GAIERVLGGFAltllvppehyaaalrwvnRLHlrgrlvyervRTGLPDPERPRLDPDSLAGKLDFKPHPF 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1241 CERTKALLEAKTNELVCTS----RDKADAILArlsQCQ-RHTATVGEALLRRMG------------QVSELEAQLTQLTE 1303
Cdd:COG4913    548 RAWLEAELGRRFDYVCVDSpeelRRHPRAITR---AGQvKGNGTRHEKDDRRRIrsryvlgfdnraKLAALEAELAELEE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1304 EQRTLKSSFQQVTNQLEEKEKQIKTMKA---------DIEGLLTEKEALQqeggQQRQAASEKESCITQLKKELAENINA 1374
Cdd:COG4913    625 ELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAELE----AELERLDASSDDLAALEEQLEELEAE 700

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 1907198992 1375 VTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISAL 1419
Cdd:COG4913    701 LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745
Gp58 pfam07902
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
 599-853 3.15e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 42.63  E-value: 3.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  599 TSLEKSLQESKTQSEHLAVHLEAEKNK-----------------HNKELTA----LAEQHRTEVEGLQQQQDSLWTERLQ 657
Cdd:pfam07902   74 TGLFKSLEEMLSQLKELNLELTDTKNSnlwskiklnnngmlreyHNDTIKTeiveSAEGIATRISEDTDKKLALINETIS 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  658 SLSQQHQAAVEELREKYQQEKDAL---LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEAlrARDQLAEELSV 734
Cdd:pfam07902  154 GIRREYQDADRQLSSSYQAGIEGLkatMASDKIGLQAEIQASAQGLSQRYDNEIRKLSAKITTTSSG--TTEAYESKLDD 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  735 LRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKAlkdeLSRLGALLDerdehlrERQARVQDLEahlqKS 814
Cdd:pfam07902  232 LRAEFTRSNQGMRTELESKISGLQSTQQSTAYQISQEISNREGA----VSRVQQDLD-------SYQRRLQDAE----KN 296

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1907198992  815 AGELQQALAKLdllhseQSAAREQAGAYEEQLAQMQ----QKV 853
Cdd:pfam07902  297 YSSLTQTVKGL------QSTVSDPNSKLESRITQLAglieQKV 333
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 845-1025 3.42e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 3.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  845 QLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNSTVEKEQA 923
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVeARIKKYEEQLGNVRNNKE 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  924 RQSLMekeniilqmreeqaKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 1003
Cdd:COG1579     91 YEALQ--------------KEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA 156

                          170       180
                   ....*....|....*....|..
gi 1907198992 1004 ELENTVLELSQKEKQFNAQILE 1025
Cdd:COG1579    157 ELEELEAEREELAAKIPPELLA 178
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1575-1718 3.42e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.54  E-value: 3.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1575 RDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELgtvkkelehvnssvKSRDGELKALEDKLElesa 1654
Cdd:COG2433    390 LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEL--------------EEKDERIERLERELS---- 451

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198992 1655 akvELKRKAEQKIaairkqllsqmeeKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1718
Cdd:COG2433    452 ---EARSEERREI-------------RKDREISRLDREIERLERELEEERERIEELKRKLERLK 499
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1104-1328 3.44e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1104 QSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLL 1183
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1184 AdKSQLRVSELTGQvQAAEKELQSCKSLHELSKKSLEDKSLN--LKSLLEELASQLDsRCERTKALLEAKTNELvctsRD 1261
Cdd:COG4942    106 L-AELLRALYRLGR-QPPLALLLSPEDFLDAVRRLQYLKYLApaRREQAEELRADLA-ELAALRAELEAERAEL----EA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907198992 1262 KADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKT 1328
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 362-1089 3.47e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.73  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  362 CALLLSEKEALQEQLDERLQELEKMKGMVITETkrqmlETLELKEDEIAQLRSHIKQMTTQGEELREqKEKSERAAFEEL 441
Cdd:TIGR00606  414 CADLQSKERLKQEQADEIRDEKKGLGRTIELKK-----EILEKKQEELKFVIKELQQLEGSSDRILE-LDQELRKAEREL 487

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  442 EKA-----LSTAQKTEDAQRRMKMEMDEQMKAVERASEEERlrlQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELAS 516
Cdd:TIGR00606  488 SKAeknslTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLN---HHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTS 564

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  517 KEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQeAEAYRTRILE 596
Cdd:TIGR00606  565 LLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCG-SQDEESDLER 643

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  597 LETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQ 676
Cdd:TIGR00606  644 LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  677 EKDALLKEKESlfQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEEL-------SVLRGDADKMKQALEAE 749
Cdd:TIGR00606  724 RRDEMLGLAPG--RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpeeesaKVCLTDVTIMERFQMEL 801

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  750 LEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARvQDLEAHLQKSAGELQQALAKLdllh 829
Cdd:TIGR00606  802 KDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQ-QEQIQHLKSKTNELKSEKLQI---- 876

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  830 seqSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKhvceeldaqraQVQQLERQRSELEEKVRSLAQLQ 909
Cdd:TIGR00606  877 ---GTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLE-----------KDQQEKEELISSKETSNKKAQDK 942

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  910 DSQLKNSTVEKEQARQSLmekENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQE 989
Cdd:TIGR00606  943 VNDIKEKVKNIHGYMKDI---ENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQD 1019

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  990 --TKKKLLDQEAKLKKELENTVLELSQKekqfnaQILEMAQANsagisdtvSRLEENQRqqiesLTGAHQRKLDDVIEAW 1067
Cdd:TIGR00606 1020 nlTLRKRENELKEVEEELKQHLKEMGQM------QVLQMKQEH--------QKLEENID-----LIKRNHVLALGRQKGY 1080

                          730       740
                   ....*....|....*....|..
gi 1907198992 1068 EKKLSQQAAELRDKHAEQMEEK 1089
Cdd:TIGR00606 1081 EKEIKHFKKELREPQFRDAEEK 1102
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1084-1703 3.68e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 3.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1084 EQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEA-- 1161
Cdd:PRK03918   158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEElk 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1162 -DLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE-----DKSLNLKSLLEELAS 1235
Cdd:PRK03918   238 eEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKlsefyEEYLDELREIEKRLS 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1236 QLDSRCERTKALLE--AKTNELVCTSRDKADAILARLSQCQRHTATVGEAlLRRMGQVSELEAQLTQLTEEqrtlkssfq 1313
Cdd:PRK03918   318 RLEEEINGIEERIKelEEKEERLEELKKKLKELEKRLEELEERHELYEEA-KAKKEELERLKKRLTGLTPE--------- 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1314 QVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKES-------CITQLKKELAENINAVtlLREELSEKK 1386
Cdd:PRK03918   388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvCGRELTEEHRKELLEE--YTAELKRIE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1387 SEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEkmsaLEQVDHWSNKFsewk 1466
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEE----YEKLKEKLIKL---- 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1467 KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQIC-LLKEDLDRQNKKFECLKGEMEvRKSKMEKKECDLETALKTQTA 1545
Cdd:PRK03918   538 KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAeLLKELEELGFESVEELEERLK-ELEPFYNEYLELKDAEKELER 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1546 RVVELEDCVTQRKKEVESLNETLKNYNQQRdtehsglvqrlQHLEELGEE-KDNKVREAEETVLRLREHVSSLEAELGTV 1624
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELAETEKRLEELR-----------KELEELEKKySEEEYEELREEYLELSRELAGLRAELEEL 685

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907198992 1625 KKELEHVNSSVKSRDGELKALEDKLElesaaKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKER 1703
Cdd:PRK03918   686 EKRREEIKKTLEKLKEELEEREKAKK-----ELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEELTEG 759
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 190-760 3.75e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.65  E-value: 3.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  190 REQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQ--------SQDKSLRRISE----LREELQMDQQAK 257
Cdd:TIGR00618  309 AQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQeihirdahEVATSIREISCqqhtLTQHIHTLQQQK 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  258 KHLQDEFDACLEEKDQYISVLQTQVSLLKQRlqngpmnvdapkplPPGELQAEVHGDTEKMEGVGEPVGGGTSAKTLEML 337
Cdd:TIGR00618  389 TTLTQKLQSLCKELDILQREQATIDTRTSAF--------------RDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCE 454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  338 QQRVKRQENLLQRCKETIG--SHKEQCALLLSEKEALQEQLDERLQELEKM--KGMVITETKRQMLETLELKEDEIAQLR 413
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQqlQTKEQIHLQETRKKAVVLARLLELQEEPCPlcGSCIHPNPARQDIDNPGPLTRRMQRGE 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  414 SHIKQMTTQGEELREQKEkSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEeerlRLQHELsrvrqeaas 493
Cdd:TIGR00618  535 QTYAQLETSEEDVYHQLT-SERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV----RLQDLT--------- 600

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  494 maKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAIL 573
Cdd:TIGR00618  601 --EKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASR 678

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  574 TESENKLQELGQEAEAYR---TRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAE-------------QH 637
Cdd:TIGR00618  679 QLALQKMQSEKEQLTYWKemlAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQslkelmhqartvlKA 758

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  638 RTEVEGLQQQQDSLWTERLQSLsqQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSE 717
Cdd:TIGR00618  759 RTEAHFNNNEEVTAALQTGAEL--SHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSR 836

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907198992  718 LSEalraRDQLAEELSVLRGDADKMKQALEAELEEQRRHHQRE 760
Cdd:TIGR00618  837 LEE----KSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1956-2148 3.79e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 3.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1956 QKLSKEVARLQKELRALRREH------QQELDILKRECEQEAE-EKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQEL 2028
Cdd:COG3206    185 PELRKELEEAEAALEEFRQKNglvdlsEEAKLLLQQLSELESQlAEARAELAEAEARLAALRAQLGSGPDALPELLQSPV 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2029 ERTVQETIDKAQEVEAELLESHQEET---QQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQ 2105
Cdd:COG3206    265 IQQLRAQLAELEAELAELSARYTPNHpdvIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLA 344

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1907198992 2106 QRLEQEestkdsVTILELQTQLAQKTTLISD--SKLKEQELREQV 2148
Cdd:COG3206    345 ELPELE------AELRRLEREVEVARELYESllQRLEEARLAEAL 383
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 975-1590 4.17e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 42.43  E-value: 4.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  975 KRMEKIKQKAKEMQETKKKLLDQEAKLKKE-LENTVLELSQKEKQFNAQILEMAQAnsaGISDTVSRLEENQRQQIESLT 1053
Cdd:pfam07111   70 RQLQELRRLEEEVRLLRETSLQQKMRLEAQaMELDALAVAEKAGQAEAEGLRAALA---GAEMVRKNLEEGSQRELEEIQ 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1054 GAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQkVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQG 1133
Cdd:pfam07111  147 RLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQ-LAEAQKEAELLRKQLSKTQEELEAQVTLVESLRK 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1134 QLEQKSAVIVSLSERESQLQSQVEKLEadlgcslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSckslhe 1213
Cdd:pfam07111  226 YVGEQVPPEVHSQTWELERQELLDTMQ-----------HLQEDRADLQATVELLQVRVQSLTHMLALQEEELTR------ 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1214 lskksledKSLNLKSLLEELASqldsrcertkalleaKTNELVCTSRDKADAILARL-SQCQRHTATVGEAllrrMGQVS 1292
Cdd:pfam07111  289 --------KIQPSDSLEPEFPK---------------KCRSLLNRWREKVFALMVQLkAQDLEHRDSVKQL----RGQVA 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1293 ELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQ-------AASEKESCITQLK 1365
Cdd:pfam07111  342 ELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEEqlkfvvnAMSSTQIWLETTM 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1366 KELAENINAVTLLREELSEKKSEIAS----LSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKV 1441
Cdd:pfam07111  422 TRVEQAVARIPSLSNRLSYAVRKVHTikglMARKVALAQLRQESCPPPPPAPPVDADLSLELEQLREERNRLDAELQLSA 501

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1442 DALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKF----EC 1517
Cdd:pfam07111  502 HLIQQEVGRAREQGEAERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYgqalQE 581

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907198992 1518 LKGEMEVR-KSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLE 1590
Cdd:pfam07111  582 KVAEVETRlREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERNQELRRLQDEARKEEGQRLARRVQELE 655
PLN02939 PLN02939
transferase, transferring glycosyl groups
 909-1232 4.26e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.58  E-value: 4.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  909 QDSQLKN----STVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILH-EEYETKFKNQEKRMEKIKQK 983
Cdd:PLN02939    71 ENGQLENtslrTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQlEDLVGMIQNAEKNILLLNQA 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  984 AKEMQETKKKLLDQEAKLKKELENTVLELSQK--------EKQFNAQIL---------EMAQANSAGISDTVSRLEENQR 1046
Cdd:PLN02939   151 RLQALEDLEKILTEKEALQGKINILEMRLSETdariklaaQEKIHVEILeeqleklrnELLIRGATEGLCVHSLSKELDV 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1047 QQIESLTgahqrkLDDVIEAWEKKLS--QQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEEL-TKEVARLKEAVSG 1123
Cdd:PLN02939   231 LKEENML------LKDDIQFLKAELIevAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLsPLQYDCWWEKVEN 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1124 QDVALAGLQGQLEQKSAVIvslsERESQLQSQVEKLEADLGCSLSEKLSLQeelaelklLADKSQLRVSELTGQVQAAEK 1203
Cdd:PLN02939   305 LQDLLDRATNQVEKAALVL----DQNQDLRDKVDKLEASLKEANVSKFSSY--------KVELLQQKLKLLEERLQASDH 372

                          330       340
                   ....*....|....*....|....*....
gi 1907198992 1204 ELQSCKSLHELSKKSLEDkslNLKSLLEE 1232
Cdd:PLN02939   373 EIHSYIQLYQESIKEFQD---TLSKLKEE 398
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 365-1255 4.34e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 4.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  365 LLSEKEALQEQLDERLQELEkmkgmvitETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFE-ELEK 443
Cdd:pfam01576   55 LCAEAEEMRARLAARKQELE--------EILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKlQLEK 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  444 ALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERL-RLQHELSRVRQEAASMAK-KNSEEQVAA--LQKLHAEELASKEQ 519
Cdd:pfam01576  127 VTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERIsEFTSNLAEEEEKAKSLSKlKNKHEAMISdlEERLKKEEKGRQEL 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  520 E-LSRRLEARERELQEQmrIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELgqeaeayRTRILELE 598
Cdd:pfam01576  207 EkAKRKLEGESTDLQEQ--IAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIREL-------EAQISELQ 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  599 TSLEKSLQ---ESKTQSEHLAVHLEAEKNKHNKELTALAEQHrtEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQ 675
Cdd:pfam01576  278 EDLESERAarnKAEKQRRDLGEELEALKTELEDTLDTTAAQQ--ELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHT 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  676 QEKDALlkeKESLFQAHIQDMNektlekLDKKQMELESVSSELSEALRArdqlaeeLSVLRGDADKMKQALEAELEEQRR 755
Cdd:pfam01576  356 QALEEL---TEQLEQAKRNKAN------LEKAKQALESENAELQAELRT-------LQQAKQDSEHKRKKLEGQLQELQA 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  756 HHQREVGSISEQQELTVRraekaLKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAA 835
Cdd:pfam01576  420 RLSESERQRAELAEKLSK-----LQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQL 494

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  836 REQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEM--------------ETHKKHVCEELDAQR-------AQVQQLERQ 894
Cdd:pfam01576  495 EDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMkkkleedagtlealEEGKKRLQRELEALTqqleekaAAYDKLEKT 574

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  895 RSELEEKVRSLAQLQDSQLKN-STVEKEQAR--QSLMEKENIILQMREE------QAKEIEILKQTLSSKEESISILHEE 965
Cdd:pfam01576  575 KNRLQQELDDLLVDLDHQRQLvSNLEKKQKKfdQMLAEEKAISARYAEErdraeaEAREKETRALSLARALEEALEAKEE 654

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  966 YETKFKNQEKRMEK-------IKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEkqfnaqilemaqansagisDTV 1038
Cdd:pfam01576  655 LERTNKQLRAEMEDlvsskddVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATE-------------------DAK 715

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1039 SRLEENqrqqIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGEL--RQKVRIVQSEKEELTKEVAR 1116
Cdd:pfam01576  716 LRLEVN----MQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVaaKKKLELDLKELEAQIDAANK 791

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1117 LKEAVSGQdvaLAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTG 1196
Cdd:pfam01576  792 GREEAVKQ---LKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELAD 868

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907198992 1197 QVQAAekelQSCKSLHELSKKSLEDKSLNLKSLLEELASQ---LDSRCERTKALLEAKTNEL 1255
Cdd:pfam01576  869 EIASG----ASGKSALQDEKRRLEARIAQLEEELEEEQSNtelLNDRLRKSTLQVEQLTTEL 926
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1489-2158 4.58e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 4.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1489 VKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEK---KECDLETALKTQTARVVELEDCVTQRKKEVESLN 1565
Cdd:PRK03918   141 LESDESREKVVRQILGLDDYENAYKNLGEVIKEIKRRIERLEKfikRTENIEELIKEKEKELEEVLREINEISSELPELR 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1566 ETLKNYnqqrdtehSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKAL 1645
Cdd:PRK03918   221 EELEKL--------EKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK----ELKEL 288

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1646 EDKlELESAAKVELKRKAEQKIAAIRKQL--LSQMEEKTQRYAKDTEN---RLSELSAQLKEREKQVHSLEDKLKNLEss 1720
Cdd:PRK03918   289 KEK-AEEYIKLSEFYEEYLDELREIEKRLsrLEEEINGIEERIKELEEkeeRLEELKKKLKELEKRLEELEERHELYE-- 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1721 phpEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARpsqpEAQHRALSGKLDC 1800
Cdd:PRK03918   366 ---EAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELK----KAIEELKKAKGKC 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1801 -TRARQLEDHVLIGCLPEELEEkmkcslivsqpmgeetgnntgvkqnwasvVDSVQKTLQEKELTCQALEQRVKELESDL 1879
Cdd:PRK03918   439 pVCGRELTEEHRKELLEEYTAE-----------------------------LKRIEKELKEIEEKERKLRKELRELEKVL 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1880 VRERgahrlEVEKLTLKYEKSQSSQQEMDGENkcvevLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLtgaeRDKQKLS 1959
Cdd:PRK03918   490 KKES-----ELIKLKELAEQLKELEEKLKKYN-----LEELEKKAEEYEKLKEKLIKLKGEIKSLKKEL----EKLEELK 555

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1960 KEVARLQKELRALRREHQQELDILKR---ECEQEAEEKLKQeqedlelkhtstLKQLMREFNTqLAQKEQELERtvqeti 2036
Cdd:PRK03918   556 KKLAELEKKLDELEEELAELLKELEElgfESVEELEERLKE------------LEPFYNEYLE-LKDAEKELER------ 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2037 dkaqevEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKD 2116
Cdd:PRK03918   617 ------EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRRE 690

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907198992 2117 SV--TILELQTQLAQKTTLISDSKLKE------QELREQVHNLEDRLKRY 2158
Cdd:PRK03918   691 EIkkTLEKLKEELEEREKAKKELEKLEkalervEELREKVKKYKALLKER 740
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
703-828 4.86e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.57  E-value: 4.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  703 KLDKKQMELESVSSELsEALRARDQLAEELSVLRGDADKMKQALE-AELEEQRRHHQREVGSISEQQELTVRRAEKALKD 781
Cdd:COG1566     84 ALAQAEAQLAAAEAQL-ARLEAELGAEAEIAAAEAQLAAAQAQLDlAQRELERYQALYKKGAVSQQELDEARAALDAAQA 162

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1907198992  782 ELSRLGALLDERDEHLRErQARVQDLEAHLQKSAGELQQALAKLDLL 828
Cdd:COG1566    163 QLEAAQAQLAQAQAGLRE-EEELAAAQAQVAQAEAALAQAELNLART 208
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 374-482 5.10e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.99  E-value: 5.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  374 EQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGE-------ELREQKEKSERAAFE--ELEKA 444
Cdd:COG0542    414 DELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEaekelieEIQELKEELEQRYGKipELEKE 493

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1907198992  445 LSTAQKTEDAQRRM-KMEMDEQMKA----------VERASEEERLRLQH 482
Cdd:COG0542    494 LAELEEELAELAPLlREEVTEEDIAevvsrwtgipVGKLLEGEREKLLN 542
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1619-1975 5.85e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 5.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1619 AELGTVKKELEHVNSSVKSRDGELKALEDKLE--LESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSEL 1696
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREkaERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1697 SAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDcTHKACKERLCMLQRRLSEKEKLLRRLE 1776
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLER-SIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1777 qgegearpsqpeAQHRALSGKLDCTRARQLEdhvligcLPEELEEKmkcslivsqpmgeetgnntgvkqnwASVVDSVQK 1856
Cdd:TIGR02169  336 ------------AEIEELEREIEEERKRRDK-------LTEEYAEL-------------------------KEELEDLRA 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1857 TLQEKELTCQALEQRVKELE---SDLVRERGAHRLEVEKLtlKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSN 1933
Cdd:TIGR02169  372 ELEEVDKEFAETRDELKDYReklEKLKREINELKRELDRL--QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE 449

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1907198992 1934 VGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRRE 1975
Cdd:TIGR02169  450 IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 930-1152 6.01e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 6.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  930 KENIIlqmreEQAKEIeilkqtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTV 1009
Cdd:PRK00409   500 PENII-----EEAKKL------IGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLL 568

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1010 LELSQKEKqfnaQILEMAQANSAGIsdtVSRLEENQRQQIESLtgahqrKLDDVIEAweKKLSQQAAELRDKHAEQMEEK 1089
Cdd:PRK00409   569 EEAEKEAQ----QAIKEAKKEADEI---IKELRQLQKGGYASV------KAHELIEA--RKRLNKANEKKEKKKKKQKEK 633

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907198992 1090 EQGL--GE------LRQKVRIVQ-SEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQL 1152
Cdd:PRK00409   634 QEELkvGDevkylsLGQKGEVLSiPDDKEAIVQAGIMKMKVPLSDLEKIQKPKKKKKKKPKTVKPKPRTVSL 705
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1938-2048 6.10e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 6.10e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  1938 DGLRSDLESKLTGAERDKQKLSKE-------VARLQKELRALRREHQQeLDILKRECEQEAEEKLKQEQEDLElkhtSTL 2010
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKElellnsiKPKLRDRKDALEEELRQ-LKQLEDELEDCDPTELDRAKEKLK----KLL 217

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 1907198992  2011 KQLMREFN--TQLAQKEQELERTVQETIDKAQEVEAELLE 2048
Cdd:smart00787  218 QEIMIKVKklEELEEELQELESKIEDLTNKKSELNTEIAE 257
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
241-519 6.11e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 6.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  241 RRISELREELQMDQQAKKHLQDEFDACLEEKDQyisvLQTQVSLLKQRLQNGPMNVDAPkplppgELQAEVHgdtekmEG 320
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDA----LQERREALQRLAEYSWDEIDVA------SAEREIA------EL 673

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  321 VGEPVGGGTSAKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETkRQMLE 400
Cdd:COG4913    674 EAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL-RALLE 752

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  401 TLELKEDEIAQLRSHIKQMTTQGEELREQKEKSEraafEELEKALStaqkteDAQRRMKMEMDEQMKAVERASE-EERLR 479
Cdd:COG4913    753 ERFAAALGDAVERELRENLEERIDALRARLNRAE----EELERAMR------AFNREWPAETADLDADLESLPEyLALLD 822

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1907198992  480 --LQHELSRVRQEAASMAKKNSEEQVAALQ-KLHAEELASKEQ 519
Cdd:COG4913    823 rlEEDGLPEYEERFKELLNENSIEFVADLLsKLRRAIREIKER 865
PRK01156 PRK01156
chromosome segregation protein; Provisional
 577-1119 6.71e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.81  E-value: 6.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  577 ENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSE----------------HLAVHLEAEKNKHNKELTALaeQHRTE 640
Cdd:PRK01156   189 EEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIeynnamddynnlksalNELSSLEDMKNRYESEIKTA--ESDLS 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  641 VEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAhiqDMNEKTLEKLDKKQMELESVSSELSE 720
Cdd:PRK01156   267 MELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNI---DAEINKYHAIIKKLSVLQKDYNDYIK 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  721 ALRARDQLAEELSVLRGDADKMKQALEA--ELEEQRRHHQREVGSISEQQELTVRRAE---KALKDELSRLGALLDERDE 795
Cdd:PRK01156   344 KKSRYDDLNNQILELEGYEMDYNSYLKSieSLKKKIEEYSKNIERMSAFISEILKIQEidpDAIKKELNEINVKLQDISS 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  796 HLRERQARVQDLEAHLQksagELQQALAKLD--------LLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQV 867
Cdd:PRK01156   424 KVSSLNQRIRALRENLD----ELSRNMEMLNgqsvcpvcGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKI 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  868 VEMETHKKHVC-EELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKnstvekeqarqslmeKENIILQMReeqAKEIE 946
Cdd:PRK01156   500 VDLKKRKEYLEsEEINKSINEYNKIESARADLEDIKIKINELKDKHDK---------------YEEIKNRYK---SLKLE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  947 ILKQTLSSKEESISILHE-EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNaqile 1025
Cdd:PRK01156   562 DLDSKRTSWLNALAVISLiDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYN----- 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1026 MAQANSAGIsDTVSRLEENQRQQIESLtgahqrkldDVIEAWEKKLSQQAAELRD---KHAEQMEEKEQGLGELRQKVRI 1102
Cdd:PRK01156   637 EIQENKILI-EKLRGKIDNYKKQIAEI---------DSIIPDLKEITSRINDIEDnlkKSRKALDDAKANRARLESTIEI 706

                          570
                   ....*....|....*..
gi 1907198992 1103 VQSEKEELTKEVARLKE 1119
Cdd:PRK01156   707 LRTRINELSDRINDINE 723
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 891-1119 8.24e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 8.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  891 LERQRSELEEKVRSL--AQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYET 968
Cdd:PRK05771    14 LKSYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEE 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  969 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKeLENTVLELsqkekqfnaqILEMAQANSAGISDTVSRLEENQRQQ 1048
Cdd:PRK05771    94 ELEKIEKEIKELEEEISELENEIKELEQEIERLEP-WGNFDLDL----------SLLLGFKYVSVFVGTVPEDKLEELKL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1049 IESLTGA---HQRKLDDVIEAW-EKKLSQQAAELRDKH-AEQMEEKEQG-----LGELRQKVRIVQSEKEELTKEVARLK 1118
Cdd:PRK05771   163 ESDVENVeyiSTDKGYVYVVVVvLKELSDEVEEELKKLgFERLELEEEGtpselIREIKEELEEIEKERESLLEELKELA 242


                   .
gi 1907198992 1119 E 1119
Cdd:PRK05771   243 K 243
PRK11281 PRK11281
mechanosensitive channel MscK;
990-1408 8.26e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.44  E-value: 8.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992  990 TKKKLLDQEAKL-KKELENTVLELSQKEKQfnaqilemaqansagisdtvsrleenqRQQIESLtgahqrklddvieawE 1068
Cdd:PRK11281    49 NKQKLLEAEDKLvQQDLEQTLALLDKIDRQ---------------------------KEETEQL---------------K 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1069 KKLSQQAAELRDKHAEQMEEKEQGLGELRQK-----VRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIV 1143
Cdd:PRK11281    87 QQLAQAPAKLRQAQAELEALKDDNDEETRETlstlsLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALY 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1144 SLSERESQLQSQVEKLEAD-LGCSLSEKLSLQEELAEL--------KLLADKSQL------RVSELTGQVQAAEKELQ-- 1206
Cdd:PRK11281   167 ANSQRLQQIRNLLKGGKVGgKALRPSQRVLLQAEQALLnaqndlqrKSLEGNTQLqdllqkQRDYLTARIQRLEHQLQll 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1207 ----SCKSLHELSKKSLEDKSLNLKSLLEE---LASQLDSRCERTKALLEA--KTNELvctSRD--KADAILARLSQCQR 1275
Cdd:PRK11281   247 qeaiNSKRLTLSEKTVQEAQSQDEAARIQAnplVAQELEINLQLSQRLLKAteKLNTL---TQQnlRVKNWLDRLTQSER 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1276 HtatvgeallrrmgqvseLEAQLTQLteeQRTLKSS---FQQvtNQLEEKEKQIKTMKADIEGLLTEkealQQEGGQQRQ 1352
Cdd:PRK11281   324 N-----------------IKEQISVL---KGSLLLSrilYQQ--QQALPSADLIEGLADRIADLRLE----QFEINQQRD 377

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907198992 1353 AASEKESCITQLKKELAENINAVTL--LREELSEKKSEIASLSKQlsdLGAQLESSIS 1408
Cdd:PRK11281   378 ALFQPDAYIDKLEAGHKSEVTDEVRdaLLQLLDERRELLDQLNKQ---LNNQLNLAIN 432
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1290-1405 9.01e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 9.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907198992 1290 QVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKAD--IEGLLTEKEALQQEGGQQRQAASEKESCITQLKKE 1367
Cdd:COG3206    220 QLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQ 299

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1907198992 1368 LAENINAV-TLLREELSEKKSEIASLSKQLSDLGAQLES 1405
Cdd:COG3206    300 IAALRAQLqQEAQRILASLEAELEALQAREASLQAQLAQ 338
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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