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Conserved domains on  [gi|1907187812|ref|XP_036009727|]
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ufm1-specific protease 2 isoform X3 [Mus musculus]

Protein Classification

C78 family peptidase( domain architecture ID 10546049)

C78 family peptidase is a cysteine peptidase similar to human Ufm1-specific protease 2 (UFSP2) which cleaves the peptide bond at the C-terminal Gly of ubiquitin-fold modifier-1 protein and to human zinc finger-containing ubiquitin peptidase 1 (ZUP1, also known as ZUFSP) which cleaves 'Lys-63'-linked long polyubiquitin chains

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peptidase_C78 pfam07910
Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine ...
 93-274 2.51e-87

Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine peptidase called (Ufm1)-specific protease.


:

Pssm-ID: 400318  Cd Length: 199  Bit Score: 258.75  E-value: 2.51e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907187812  93 VVQGTYAYHHYMQDRIDDNGWGCAYRSLQTICSWFRHQGYT---ERSIPTHREIQQALVDAGDKPA---TFVGSRQWIGS 166
Cdd:pfam07910   5 LVLGSYDYYHYMQDGFNDKGWGCGYRNLQMLLSWLLLNGYTgkpQFTVPTIPEIQQMLEDAWDKGFdsqGFVGSRKWIGT 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907187812 167 IEVQMVLNQLIGVTSKILFVNQGSEM---ASQGRELANHF-QNVGTPVMVG--GGVLAHTILGVAWNEtTGQIKFLILDP 240
Cdd:pfam07910  85 TEASAVLTSLLGVDCKIVDFKSGSELgthPELFDEVANYFeSTSGPPIYLQhqGHVYSRTILGVEINA-NGELNLLILDP 163

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1907187812 241 HYTGAED-LQVMLEKGWCGW-KSPDFWNKDAYYNLC 274
Cdd:pfam07910 164 HYTGADDsLKLVGDKGWVGWkKGVDFLKKHKFYNLC 199
 
Name Accession Description Interval E-value
Peptidase_C78 pfam07910
Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine ...
 93-274 2.51e-87

Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine peptidase called (Ufm1)-specific protease.


Pssm-ID: 400318  Cd Length: 199  Bit Score: 258.75  E-value: 2.51e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907187812  93 VVQGTYAYHHYMQDRIDDNGWGCAYRSLQTICSWFRHQGYT---ERSIPTHREIQQALVDAGDKPA---TFVGSRQWIGS 166
Cdd:pfam07910   5 LVLGSYDYYHYMQDGFNDKGWGCGYRNLQMLLSWLLLNGYTgkpQFTVPTIPEIQQMLEDAWDKGFdsqGFVGSRKWIGT 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907187812 167 IEVQMVLNQLIGVTSKILFVNQGSEM---ASQGRELANHF-QNVGTPVMVG--GGVLAHTILGVAWNEtTGQIKFLILDP 240
Cdd:pfam07910  85 TEASAVLTSLLGVDCKIVDFKSGSELgthPELFDEVANYFeSTSGPPIYLQhqGHVYSRTILGVEINA-NGELNLLILDP 163

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1907187812 241 HYTGAED-LQVMLEKGWCGW-KSPDFWNKDAYYNLC 274
Cdd:pfam07910 164 HYTGADDsLKLVGDKGWVGWkKGVDFLKKHKFYNLC 199
 
Name Accession Description Interval E-value
Peptidase_C78 pfam07910
Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine ...
 93-274 2.51e-87

Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine peptidase called (Ufm1)-specific protease.


Pssm-ID: 400318  Cd Length: 199  Bit Score: 258.75  E-value: 2.51e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907187812  93 VVQGTYAYHHYMQDRIDDNGWGCAYRSLQTICSWFRHQGYT---ERSIPTHREIQQALVDAGDKPA---TFVGSRQWIGS 166
Cdd:pfam07910   5 LVLGSYDYYHYMQDGFNDKGWGCGYRNLQMLLSWLLLNGYTgkpQFTVPTIPEIQQMLEDAWDKGFdsqGFVGSRKWIGT 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907187812 167 IEVQMVLNQLIGVTSKILFVNQGSEM---ASQGRELANHF-QNVGTPVMVG--GGVLAHTILGVAWNEtTGQIKFLILDP 240
Cdd:pfam07910  85 TEASAVLTSLLGVDCKIVDFKSGSELgthPELFDEVANYFeSTSGPPIYLQhqGHVYSRTILGVEINA-NGELNLLILDP 163

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1907187812 241 HYTGAED-LQVMLEKGWCGW-KSPDFWNKDAYYNLC 274
Cdd:pfam07910 164 HYTGADDsLKLVGDKGWVGWkKGVDFLKKHKFYNLC 199
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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