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Conserved domains on  [gi|1720403531|ref|XP_030108372|]
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alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 isoform X8 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT29 super family cl45931
glycosyltransferase family 29; Glycosyltransferase family 29 members (also called ...
 1-214 4.37e-160

glycosyltransferase family 29; Glycosyltransferase family 29 members (also called sialyltransferases) are enzymes that transfer sialic acid to oligosaccharide, each having specificity for a certain sugar substrate.


The actual alignment was detected with superfamily member cd23975:

Pssm-ID: 480271  Cd Length: 226  Bit Score: 441.29  E-value: 4.37e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPLLLKNPDYFFKEASRTIYVIWGPFRNMRKDGNGI 80
Cdd:cd23975    13 MVGQKVGAEIDQSSCIWRMNNAPTKGYEEDVGKRTTIRVVSHTSVPLLLKNPDYFFKETNETIYVIWGPFRNMRKDGKGI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  81 VYNMLKKTVDAYPDAQIYVTTEQQMTHCDRVFKDETGKDRVQSGSYLSTGWFTFILAMDACYSIHVYGMINETYCKTEGY 160
Cdd:cd23975    93 VYNMLKKAVESYPQAKIYVTTEKRMSYCDTVFKKETGKDRVQSGSYLSTGWFTLILAMDACYGIHVYGMINDTYCKTEGY 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1720403531 161 RKVPYHYYEQGKDECNEYLLHEHAPYGGHRFITEKKVFAKWAKKHRIVFTHPNW 214
Cdd:cd23975   173 RKVPYHYYEPGRDECDEYFLHENAPYGGHRFITEKKVFAKWAKKHPITFTHPNW 226
 
Name Accession Description Interval E-value
GT29_ST6GALNAC3 cd23975
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; ST6GalNAc family members are ...
 1-214 4.37e-160

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467703  Cd Length: 226  Bit Score: 441.29  E-value: 4.37e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPLLLKNPDYFFKEASRTIYVIWGPFRNMRKDGNGI 80
Cdd:cd23975    13 MVGQKVGAEIDQSSCIWRMNNAPTKGYEEDVGKRTTIRVVSHTSVPLLLKNPDYFFKETNETIYVIWGPFRNMRKDGKGI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  81 VYNMLKKTVDAYPDAQIYVTTEQQMTHCDRVFKDETGKDRVQSGSYLSTGWFTFILAMDACYSIHVYGMINETYCKTEGY 160
Cdd:cd23975    93 VYNMLKKAVESYPQAKIYVTTEKRMSYCDTVFKKETGKDRVQSGSYLSTGWFTLILAMDACYGIHVYGMINDTYCKTEGY 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1720403531 161 RKVPYHYYEQGKDECNEYLLHEHAPYGGHRFITEKKVFAKWAKKHRIVFTHPNW 214
Cdd:cd23975   173 RKVPYHYYEPGRDECDEYFLHENAPYGGHRFITEKKVFAKWAKKHPITFTHPNW 226
Glyco_transf_29 pfam00777
Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to ...
 7-204 3.02e-14

Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to glycosyltransferase family 29.


Pssm-ID: 459935  Cd Length: 256  Bit Score: 69.17  E-value: 3.02e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   7 GEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVP---------------------LLLKNPDYFF--------- 56
Cdd:pfam00777  61 GKEIDSHDFVIRCNLAPTKGYEKDVGSKTTLRTMNPESAIdskygnlgfshprdpfvefvlVPFKGRDLLWlpafltkgn 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  57 KEASRTIYVIWGPFRNMRKDGNGIVYNmlkktvdayPDAQIYVTteqqmthcdRVFKDETGKDrvqsGSYLSTGWFTFIL 136
Cdd:pfam00777 141 VSRSLRVLYTLKEVKIPVDPDKVLFLH---------PDFLRYVA---------NFWLRSHGLK----GRRPSTGLLMLSL 198

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720403531 137 AMDACYSIHVYGMINEtycktEGYRKVPYHYYEQGKDecneyllHEHAPYGGHRFITEKKVFAKWAKK 204
Cdd:pfam00777 199 ALHLCDEVSLYGFGPF-----LDSRGNSHHYYDNVLM-------KKGGFYGVHDMPFEFKLLQKLHKE 254
 
Name Accession Description Interval E-value
GT29_ST6GALNAC3 cd23975
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; ST6GalNAc family members are ...
 1-214 4.37e-160

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467703  Cd Length: 226  Bit Score: 441.29  E-value: 4.37e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPLLLKNPDYFFKEASRTIYVIWGPFRNMRKDGNGI 80
Cdd:cd23975    13 MVGQKVGAEIDQSSCIWRMNNAPTKGYEEDVGKRTTIRVVSHTSVPLLLKNPDYFFKETNETIYVIWGPFRNMRKDGKGI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  81 VYNMLKKTVDAYPDAQIYVTTEQQMTHCDRVFKDETGKDRVQSGSYLSTGWFTFILAMDACYSIHVYGMINETYCKTEGY 160
Cdd:cd23975    93 VYNMLKKAVESYPQAKIYVTTEKRMSYCDTVFKKETGKDRVQSGSYLSTGWFTLILAMDACYGIHVYGMINDTYCKTEGY 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1720403531 161 RKVPYHYYEQGKDECNEYLLHEHAPYGGHRFITEKKVFAKWAKKHRIVFTHPNW 214
Cdd:cd23975   173 RKVPYHYYEPGRDECDEYFLHENAPYGGHRFITEKKVFAKWAKKHPITFTHPNW 226
GT29_ST6GALNAC3_4_5_6 cd23965
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3, 4, 5 and 6; ST6GalNAc family ...
 1-212 1.20e-114

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3, 4, 5 and 6; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acidand the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, bytransfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substratespecificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467693  Cd Length: 225  Bit Score: 326.12  E-value: 1.20e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPLLLKNPD-YFFKEASRTIYVIWGPFRNMRKDGNG 79
Cdd:cd23965    13 LLGSGAGKEIDSADCVIRMNDAPTRGYEKDVGRRTTIRVVSHSSLPRLLRNAIlLLAGTRAPTVVVFWGPETKMNKDGAG 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  80 IvYNMLKKTVDAYPDAQIYVTTEQQMTHCDRVFKDETGKDRVQSGSYLSTGWFTFILAMDACYSIHVYGMINETYCKTEG 159
Cdd:cd23965    93 K-YNLLRSLSKKYPDVEFYSLTPEKMDYADELFEKETGKSRIKSGTWLSTGWFTMLLALDVCDEIKVYGMVPENYCREHP 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1720403531 160 YRKVPYHYYEQ-GKDECNEYLLHEHAPYGGHRFITEKKVFAKWAKKHRIVFTHP 212
Cdd:cd23965   172 NSKVPYHYYEPgGLKECTYYNYHENALKGGHRFITEKAVFARWAKKYNITFHHP 225
GT29_ST6GALNAC4 cd23977
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; ST6GalNAc family members are ...
 1-215 6.28e-111

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467705  Cd Length: 228  Bit Score: 317.19  E-value: 6.28e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPLLLKNPDYFFKEASRTIYVIWGPFRNMRKDGNGI 80
Cdd:cd23977    13 MLGSGLGPEIDQQECVLRMNVAPTAGYEADVGNRSSLRVVSHTSVPLLLRNQGYFFQQSRDTKYVIWGPERNMDRDGGGK 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  81 VYNMLKKTVDAYPDAQIYVTTEQQMTHCDRVFKDETGKDRVQSGSYLSTGWFTFILAMDACYSIHVYGMINETYCKTEGY 160
Cdd:cd23977    93 TYRALLTLAKMYPHLQVYTLTEEKMAYCDGVFQNETGKNRMKSGSFLSTGWFTMILALELCEEILVYGMVSDSYCRNKNH 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1720403531 161 RKVPYHYYEQGK-DECNEYLLHEHAPYGGHRFITEKKVFAKWAKKHRIVFTHPNWT 215
Cdd:cd23977   173 SSVPYHYYEKGRlDECRMYLVHERAPRGGHRFITEKAIFSRWAKRKKIRFAHPSWT 228
GT29_ST6GALNAC6 cd23978
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are ...
 1-214 2.12e-83

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilizeSia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467706  Cd Length: 229  Bit Score: 247.46  E-value: 2.12e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPLLLKNPDYFFKEASRTIYVIWGPFRNMRKDGNGI 80
Cdd:cd23978    13 LLGTSLGPEIDQTECTIRMNDAPTTGYEKDVGNKTTLRVVAHSSVYRVLRRPQEFLNRTPETTLIFWGPPNKMQKDGKSN 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  81 VYNMLKKTVDAYPDAQIYVTTEQQMTHCDRVFKDETGKDRVQSGSYLSTGWFTFILAMDACYSIHVYGMINETYC-KTEG 159
Cdd:cd23978    93 LFRIIQRASMTFPNMSAFVVSPRRMRQFDDLFRGETGRDRKKSHSWLSTGWFTMVIAVELCDNVHVYGMVPPNYCsKRPT 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720403531 160 YRKVPYHYYE-QGKDECNEYLLHEHAPYGG-HRFITEKKVFAKWAKKHRIVFTHPNW 214
Cdd:cd23978   173 PKKMPYHYYEpKGPDECVTYIQNEHGRRGNhHRFITEKRVFARWAEHYNITFSHPSW 229
GT29_ST6GALNAC5 cd23976
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are ...
 1-214 3.12e-75

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc3, 4, 5, and 6 utilize Sia2,3Galbeta1,3GalNAc as an acceptor with different individual substrate specificities. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467704  Cd Length: 244  Bit Score: 227.06  E-value: 3.12e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPLLLKNPDYFFKEASRTIYVIWGPFRNMRKDGNGI 80
Cdd:cd23976    27 LTGSNRGNEIDETECVIRMNDAPTRGYGKDVGNKTSLRVIAHSSIQRILRNRNELLNVSQGTVFIFWGPSNYMRRDGKGL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  81 VYNMLKKTVDAYPDAQIYVTTEQQMTHCDRVFKDETGKDRVQSGSYLSTGWFTFILAMDACYSIHVYGMINETYCKTEGY 160
Cdd:cd23976   107 VYNNLQLMNQILPKLKVYTITRHKMLQFDELFKRETGKDRKISNTWLSTGWFTMIIALELCDRINVYGMVPPDFCRDPNH 186

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1720403531 161 RKVPYHYYE-QGKDECNEYLLHEHAPYGG-HRFITEKKVFAKWAKKHRIVFTHPNW 214
Cdd:cd23976   187 PSVPYHYYEpSGPDECTMYISHERGRKGShHRFITEKRVFANWARTFNIHFYQPDW 242
GT29 cd19952
glycosyltransferase family 29; Glycosyltransferase family 29 members (also called ...
 1-201 3.54e-39

glycosyltransferase family 29; Glycosyltransferase family 29 members (also called sialyltransferases) are enzymes that transfer sialic acid to oligosaccharide, each having specificity for a certain sugar substrate.


Pssm-ID: 467690  Cd Length: 193  Bit Score: 133.26  E-value: 3.54e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPLLLKNPDYFF---KEASRTIYVIWGPFRNMRKDg 77
Cdd:cd19952    10 LLGSEYGKEIDSHDAVFRFNQAPTKGFEKDVGSKTTFRVLNSKWAGFYLRGPRCGChplPLEEEVVLILSRAAAADFKR- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  78 ngivynmLKKTVDAYPDAQIYVTTEQQ--MTHCDRVFKDETGKDrVQSGSYLSTGWFTFILAMDACYSIHVYGMINEtyc 155
Cdd:cd19952    89 -------LKRRKKRHDNAVLLLTDPAPdlLSYVRKRLEKLGLKS-FFGGNAPSSGLLAVLLALQLCDSVDLYGFGVD--- 157

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1720403531 156 kTEGYRKVPYHYYEQGKDECneyllhehaPYGGHRFITEKKVFAKW 201
Cdd:cd19952   158 -SGHAPKVPYHYYDLVEAEE---------GTAVHSFDLEAELLRAL 193
Glyco_transf_29 pfam00777
Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to ...
 7-204 3.02e-14

Glycosyltransferase family 29 (sialyltransferase); Members of this family belong to glycosyltransferase family 29.


Pssm-ID: 459935  Cd Length: 256  Bit Score: 69.17  E-value: 3.02e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   7 GEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVP---------------------LLLKNPDYFF--------- 56
Cdd:pfam00777  61 GKEIDSHDFVIRCNLAPTKGYEKDVGSKTTLRTMNPESAIdskygnlgfshprdpfvefvlVPFKGRDLLWlpafltkgn 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  57 KEASRTIYVIWGPFRNMRKDGNGIVYNmlkktvdayPDAQIYVTteqqmthcdRVFKDETGKDrvqsGSYLSTGWFTFIL 136
Cdd:pfam00777 141 VSRSLRVLYTLKEVKIPVDPDKVLFLH---------PDFLRYVA---------NFWLRSHGLK----GRRPSTGLLMLSL 198

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720403531 137 AMDACYSIHVYGMINEtycktEGYRKVPYHYYEQGKDecneyllHEHAPYGGHRFITEKKVFAKWAKK 204
Cdd:pfam00777 199 ALHLCDEVSLYGFGPF-----LDSRGNSHHYYDNVLM-------KKGGFYGVHDMPFEFKLLQKLHKE 254
GT29_ST6GALNAC1 cd23973
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6GalNAc family members are ...
 3-205 1.13e-12

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc1 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467701  Cd Length: 309  Bit Score: 65.54  E-value: 1.13e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   3 GQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVS-HTSVPLLLKNPDYFFKEASRTIYVIWGPFRNMRKDGNGIV 81
Cdd:cd23973    97 GSKMGQEIDSHDYVFRVNGAVIKGYEEDVGTRTSFYVHTaHSITSSLMILQKRGFKNIPQDKDIKYILFPEGPRDYQWLE 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  82 YNMLKKTVDAYP----DAQIYVTTEQQMT-----HCD--RVFKDETGKDRVQSGSYL-----STGWFTFILAMDACYSIH 145
Cdd:cd23973   177 ALLKNKTIPSGAyygrRPRSYFSGDFTEDkylvlHPDflRYVKNRFLRSKTLKGKYWaiyrpTTGAFLLLTALHLCDTVS 256

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531 146 VYGMInetyckTEGYRKVPYHYYEQGKDECneyllhehAPYGGHRFITEKKVfakWAKKH 205
Cdd:cd23973   257 AYGFI------TEDYRKYPDHYYDKKKTKL--------VFYINHDFRLEKKL---WKRLH 299
GT29_ST8SIA cd23963
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8Sia family members are ...
 7-172 1.03e-11

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia. The family is subdivided into 3 classes of enzymes, depending on their catalytic activiy, the mono-STs (ST8Sia1, ST8Sia5 and ST8Sia6), the oligo-ST(ST8Sia3), and the poly-STs (ST8Sia2 and ST8Sia4). The ST8Sia family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467691  Cd Length: 274  Bit Score: 62.66  E-value: 1.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   7 GEEIDHASCIWRMNNAPTKGFEEDVGY----MTMVRVVSHTSVPLLLKNPDY-FFKEASRTI--YVIWGPfrnmrKDGNG 79
Cdd:cd23963    81 GKEIDSHDFVIRCNLPPIKGFEKDVGRktnlTTLNPSILKRRYNSLKKNRDRdKFLNRLKEYngSILWYP-----KFSFK 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  80 IVYNMLKKTVDAYPDaqiyVTTEQQMTHCDRVFKDETGK--DRVQSGSYLSTGWFTFILAMDACYSIHVYG----MINET 153
Cdd:cd23963   156 SSTNLLLKAARALKK----NGLNLTVVYSNPEHFLAVQKfwKRRGLEKRPSTGLYLVSLALTFCDEIHLYGfwpfPTDPN 231

                         170
                  ....*....|....*....
gi 1720403531 154 ycktegYRKVPYHYYEQGK 172
Cdd:cd23963   232 ------GRPVPYHYYDDLS 244
GT29_ST6GAL2 cd23986
beta-galactoside alpha-2,6-sialyltransferase 2; ST6Gal family members are beta-galactoside ...
 1-173 3.56e-11

beta-galactoside alpha-2,6-sialyltransferase 2; ST6Gal family members are beta-galactoside alpha-2,3-sialyltransferases that catalyze an alpha2,6-linkage between sialic acid and the terminal galactose residue of a glycochain, by a transfering sialic acid from CMP-Sia. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467714  Cd Length: 270  Bit Score: 61.01  E-value: 3.56e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTsvplLLKNPDYFFKEAS---RTIYVIWGP---FRNMR 74
Cdd:cd23986    61 ILNSSLGKEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTNPNHHFIDSSlykDVILVAWDPapySANLH 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  75 KDGNGIVYNMLKKTVD---AYPDAQIYVTTEQQMTHCDRVFKDETgKDRVQSGSyLSTGWFTFILAMDACYSIHVYGMIn 151
Cdd:cd23986   137 KWYKKPDYNLFTPYVQyrkRNPNQPFYILHPKFIWQLWDIIQENT-QEKIQPNP-PSSGFIGILIMMSMCREVHVYEYI- 213

                         170       180
                  ....*....|....*....|...
gi 1720403531 152 etycktEGYRKVPY-HYYEQGKD 173
Cdd:cd23986   214 ------PSVRQTDLcHYHERYYD 230
GT29_ST6GAL1_2 cd23968
beta-galactoside alpha-2,6-sialyltransferase 1 and 2; ST6Gal family members are ...
 1-69 1.93e-09

beta-galactoside alpha-2,6-sialyltransferase 1 and 2; ST6Gal family members are beta-galactosidealpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acidand the terminal galactose residue of a glycochain, by transfering sialic acid fromCMP-Sia. The ST6Gal family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467696  Cd Length: 266  Bit Score: 56.13  E-value: 1.93e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTsvpLLLKNPDYFFKEASRT--IYVIWGP 69
Cdd:cd23968    57 LLGSKLGKEIDSHDAVLRFNDAPTKGFEKDVGSKTTLRLINSQ---ILSKPEFNFLTDPLYRnvTLLVWDP 124
GT29_ST6GALNAC1_2 cd23964
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 and 2; ST6GalNAc family members ...
 3-206 1.22e-07

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 and 2; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc1 and 2 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467692  Cd Length: 292  Bit Score: 50.72  E-value: 1.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   3 GQKVGEEIDHASCIWRMNNAPTKGFEEDVG-----YMTMVR--VVSHTSVPLLLKNPDYFFkEASRT---IYVI----WG 68
Cdd:cd23964    96 GSGKGKEIDAHDYVFRVNHALTKGFEKDVGtktsfYTFFPEslHNSLLKHVPQDKDTKYLF-IPFKIrdyDYLDavlsGK 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  69 PFRNMrKDGNGIVYNMLKKTVDA------YPDAQIYVtteqqmtHCDRVfkdetgkdRVQSGSYLSTGWFTFILAMDACY 142
Cdd:cd23964   175 PVPDG-CDKGKRPPPLFGPKLNAtnvrllHPDFIRYL-------FNRWL--------NSSTSYRPTTGALMLLTALHTCD 238

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720403531 143 SIHVYGMINEtycktegyRKVPYHYYEQGKdecneyllHEHAP-YGGHRFITEKKVfakWAKKHR 206
Cdd:cd23964   239 QVSVYGFGYD--------PRFSLHYYDKTF--------VKFTVfYANHDFTNERKL---WRKLHE 284
GT29_ST3GAL1_2 cd23966
beta-galactoside alpha-2,3-sialyltransferase 1 and 2; ST3GAL family transfer sialic acid from ...
 3-209 4.19e-07

beta-galactoside alpha-2,3-sialyltransferase 1 and 2; ST3GAL family transfer sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL1 and 2 preferentially utilize the Galbeta1,3GalNAc on O-glycans of glycoproteins (core1O-glycans) and on glycolipids as an acceptor substrate, respectively. Members ofthis family belong to glycosyltransferase family 29.


Pssm-ID: 467694  Cd Length: 276  Bit Score: 49.20  E-value: 4.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   3 GQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVV---------SHTSVPLL-LKNPDY-FFKEASRTIYVIWGPFR 71
Cdd:cd23966    91 GSRYGKLIDSHDFVIRMNKAPTKGFEKDVGSKTTHHFMypesavdldPGVHLVLVpFKVLDLqWLISALTTGEITRTYTP 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  72 nmrkdgngivynmLKKTVDAYPD-AQIYVTTEQQMTHcDRVFKDEtgkdrvqsGSYLSTGWFTFILAMDACYSIHVYGMI 150
Cdd:cd23966   171 -------------VKRFIKADKDkVLVINPAFIKYVH-DNWTEHH--------GRYPSTGFLALIFALHICDEVSVFGFG 228

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720403531 151 NETYckteGYRkvpYHYYEqgkdecNEYLLHEHAPYGGHRFITEKKVFAKWAKKHRIVF 209
Cdd:cd23966   229 ADSK----GNW---HHYWE------KNRSAGAFRKTGVHDADFESDIIKKLAKEGKIRV 274
GT29_ST3GAL4 cd23982
beta-galactoside alpha-2,3-sialyltransferase 4; ST3GAL family transfers sialic acid from ...
 1-171 5.07e-07

beta-galactoside alpha-2,3-sialyltransferase 4; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL4 can utilize both Galbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates, but prefers the Galbeta1,4GlcNAc. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467710  Cd Length: 204  Bit Score: 48.51  E-value: 5.07e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVV---SHTSVPLLLKNPDYF-----FKEAS-RTIYVIWGPFR 71
Cdd:cd23982    14 LKNSSLGDVIDSYDVVIRLNDAPVRGFEKDVGSKTTIRLFypeSAQFDPGIENDPDTLlvlvpFKPLDfYWLYEILSNEK 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  72 NMRKDGngivYNMLKKTVDAYPdAQIYVTTEQQMTHCDRVFKDETGKDrvQSGSYLSTGWFTFILAMDACYSIHVYGMin 151
Cdd:cd23982    94 RVRKGF----WKQPPRIWDANP-KQIRILNPYYTYVAATKLLQVPGQR--KKKQKPTTGLLAITLALHLCDEVHIAGF-- 164

                         170       180
                  ....*....|....*....|....*
gi 1720403531 152 etyckteGY-----RKVPYHYYEQG 171
Cdd:cd23982   165 -------GYpdngnSNQPIHYYNQI 182
GT29_ST3GAL3_4_5_6 cd23967
beta-galactoside alpha-2,3-sialyltransferase 3,4,5 and 6; ST3GAL family transfers sialic acid ...
 3-40 6.81e-07

beta-galactoside alpha-2,3-sialyltransferase 3,4,5 and 6; ST3GAL family transfers sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL3 and 4 utilize bothGalbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates. ST3GAL5 is also known as GM3 ganglioside synthase. ST3GAL6 utilizes the Galbeta1,4GlcNAc on glycoproteins and glycolipids as an acceptor. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467695  Cd Length: 205  Bit Score: 48.06  E-value: 6.81e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1720403531   3 GQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVV 40
Cdd:cd23967    16 GKSLGSVIDKYDVVIRMNDAPVKGYEKDVGSKTTFRMF 53
GT29_ST6GAL1 cd23985
beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside ...
 1-69 8.98e-07

beta-galactoside alpha-2,6-sialyltransferase 1; ST6Gal family members are beta-galactoside alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the terminal galactose residue of a glycochain, by transfering sialic acid from CMP-Sia. ST6Gal1 play important roles in the immune system. The ST6Gal family belongs to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467713  Cd Length: 266  Bit Score: 48.16  E-value: 8.98e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTsvplLLKNPDYFFKEAS---RTIYVIWGP 69
Cdd:cd23985    57 LKSSGLGREIDSHDAVLRFNGAPTAGFQQDVGTKTTIRLINSQ----LVTTEKHKFLKDSlynEGILIVWDP 124
GT29_ST8SIA3_oligo cd23970
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3; Alpha-N-acetylneuraminide alpha-2, ...
 1-169 2.37e-06

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 3 synthesizes polysialic acid and has been shown to autopolysialylate. ST8Sia3 utilizes the Siaalpha2,3Galbeta1,4GlcNAc structure on N-glycans of glycoproteins and glycolipids as acceptor substrates. ST8Sia family members are alpha-N-acetylneuraminidealpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acidand the terminal sialic acid residues of glycochains, by transfering sialic acidfrom CMP-Sia and they belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467698  Cd Length: 284  Bit Score: 47.00  E-value: 2.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRvvshTSVPLLLknpDYFFKEASrTIYVIWGPFRNMRKDGNGI 80
Cdd:cd23970    80 LTNSQCGNEIDKSDFVFRCNFAPTEGFEKDVGRKTNLT----TFNPSIL---EKYYNNLL-TIQDRNNFFLSLKKLDGAI 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  81 VY---------NMLKKTVDAYPDAQIYVTTEQQ------MTHCDRVFKDETGKDRvqsgsYLSTGWFTFILAMDACYSIH 145
Cdd:cd23970   152 LWipafffhtsATVTRTLVDFFVEHRGQLKVQLawpgniMQHVNRYWKTKHLSPK-----RLSTGILMYTLASAICEEIH 226

                         170       180
                  ....*....|....*....|....
gi 1720403531 146 VYGMINETYCKTEgyRKVPYHYYE 169
Cdd:cd23970   227 LYGFWPFGFDPTG--TPLPYHYYD 248
GT29_ST3GAL1 cd23980
beta-galactoside alpha-2,3-sialyltransferase 1; ST3GAL family transfer sialic acid from ...
 7-148 3.46e-06

beta-galactoside alpha-2,3-sialyltransferase 1; ST3GAL family transfer sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL1 preferentially utilizes the Galbeta1,3GalNAc on O-glycans of glycoproteins (core1 O-glycans) as an acceptor substrate. Members of this family belong to glycosyltransferase family29 (GT29).


Pssm-ID: 467708  Cd Length: 280  Bit Score: 46.41  E-value: 3.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   7 GEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSvplllknpdyfFKEASRTIYVIWGPFR--NMRKDGNGIVYNM 84
Cdd:cd23980    99 GPQIDSHDFVLRMNKAPTEGFEADVGSKTTHHFVYPES-----------FRELAQNVSMILVPFKtlDLEWVISATTTGT 167

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720403531  85 LKKTVDAYPdAQIYVTTEQQMTHCDRVFKDETGKDRVQSGSYLSTGWFTFILAMDACYSIHVYG 148
Cdd:cd23980   168 ISHTYVPVP-RKIKVKKEKILIYHPAFIKYVFDRWLQGHGRYPSTGILSVIFSLHVCDEVDLYG 230
GT29_ST3GAL5 cd23983
beta-galactoside alpha-2,3-sialyltransferase 5; ST3GAL family transfers sialic acid from ...
 3-47 6.76e-05

beta-galactoside alpha-2,3-sialyltransferase 5; ST3GAL family transfers sialic acid from CMP-Sia to the terminalgalactose residues of glycochains through an 2,3-linkage. ST3GAL5 is also known as GM3 ganglioside synthase. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467711  Cd Length: 211  Bit Score: 42.42  E-value: 6.76e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1720403531   3 GQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPL 47
Cdd:cd23983    16 GLELGHLLDQFDIVIRLNNAPVQGYSQDVGNKTTIRMTYPEGAPK 60
GT29_ST6GALNAC2 cd23972
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; ST6GalNAc family members are ...
 3-172 2.14e-04

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. ST6GalNAc2 utilize mainly GalNAc-,Galbeta1,3GalNAc-, and Sia2,3Galbeta1,3GalNAc on O-glycans of glycoproteins as acceptors. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467700  Cd Length: 308  Bit Score: 41.35  E-value: 2.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   3 GQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMT-------------MVRVVSH--TSVPlLLKNPDYFFKEASRTIYVI- 66
Cdd:cd23972    96 GSRQGRAIDAHDYVFRLNGAVIKGFEEDVGTKTsfygftvntmknsLISYWNLgfTRTP-QGQDLQYIFIPSDIRDYVMl 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  67 ----------------------WGPFRNMRKdgngivYNMLkktvdaYPDAQIYVTteqqmthcDRVFKDETGKDRVQSG 124
Cdd:cd23972   175 rsailgvpvpegldkgdrphkyFGPEASAKK------FKLL------HPDFISYLT--------DRFLKSKLLNTHYGHL 234

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1720403531 125 SYLSTGWFTFILAMDACYSIHVYGMInetyckTEGYRKVPYHYYEQGK 172
Cdd:cd23972   235 YMPSTGALMLLTALHTCDQVSAYGFI------TSNYWKFSDHYYERKK 276
GT29_ST3GAL3 cd23981
beta-galactoside alpha-2,3-sialyltransferase 3; ST3GAL family transfers sialic acid from ...
 1-39 3.71e-04

beta-galactoside alpha-2,3-sialyltransferase 3; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL3 can utilize both Galbeta1,3GlcNAc and Galbeta1,4GlcNAc, mainly on glycoproteins and oligosaccharidesas acceptor substrates, but prefers the Galbeta1,3GlcNAc. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467709  Cd Length: 207  Bit Score: 40.29  E-value: 3.71e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1720403531   1 MVGQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMTMVRV 39
Cdd:cd23981    14 LANKSLGSKIDDYDVVVRLNSAPVKGFEKDVGSKTTLRI 52
GT29_ST3GAL6 cd23984
beta-galactoside alpha-2,3-sialyltransferase 6; ST3GAL family transfers sialic acid from ...
 7-38 5.12e-04

beta-galactoside alpha-2,3-sialyltransferase 6; ST3GAL family transfers sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL6 utilizes the Galbeta1,4GlcNAc on glycoproteins and glycolipids as an acceptor. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467712  Cd Length: 206  Bit Score: 39.73  E-value: 5.12e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1720403531   7 GEEIDHASCIWRMNNAPTKGFEEDVGYMTMVR 38
Cdd:cd23984    20 GKKIDSYDVIIRMNNGPVIGYENDVGKRTTFR 51
GT29_ST8SIA_poly cd23969
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2 and 4; ST8Sia2 and 4 are known to be ...
 7-172 1.61e-03

alpha-N-acetylneuraminide alpha-2,8-sialyltransferase 2 and 4; ST8Sia2 and 4 are known to be polysialyltransferases, and they can synthesize polysialic acid on neural cell adhesion molecules (NCAMs). ST8Sia family members are alpha-N-acetylneuraminide alpha-2,8-sialyltransferases that catalyze an alpha-2,8-linkage between sialic acid and the terminal sialic acid residues of glycochains, by transfering sialic acid from CMP-Sia and they belong to the glycosyltransferase family 29 (GT29).


Pssm-ID: 467697  Cd Length: 276  Bit Score: 38.55  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531   7 GEEIDHASCIWRMNNAPTKGFEEDVG----YMTMVRVVSHTSVPLLLKNPDY-FFKEASRTIY--VIWGP-FrnMRKDG- 77
Cdd:cd23969    82 GQEIDSHDFVIRCNLAPVEGYEKDVGtksnLTTMNPSVIPHAYGDLVNATDKeKFVERLRQLGdsILWIPaF--VSKGGe 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403531  78 ------NGIVYNMLKKTVDAYPDAQIYvtteqqmtHCDRVFKDETgKDRVQSGSylsTGWFTFILAMDACYSIHVYGMIn 151
Cdd:cd23969   160 ehvqwtNEIILKHKLNVKTAYPPLRLN--------HAIRGYWLTT-KFRIKRPS---TGLLMYTLATRFCDEIHLYGFY- 226

                         170       180
                  ....*....|....*....|.
gi 1720403531 152 eTYCKTEGYRKVPYHYYEQGK 172
Cdd:cd23969   227 -PFSEDGNGRAVKYHYYDNRK 246
GT29_ST3GAL2 cd23979
beta-galactoside alpha-2,3-sialyltransferase 2; ST3GAL family transfer sialic acid from ...
 3-35 2.00e-03

beta-galactoside alpha-2,3-sialyltransferase 2; ST3GAL family transfer sialic acid from CMP-Sia to the terminal galactose residues of glycochains through an 2,3-linkage. ST3GAL2 preferentially utilizes the Galbeta1,3GalNAc on glycolipids as an acceptor substrate. Members of this family belong to glycosyltransferase family 29 (GT29).


Pssm-ID: 467707  Cd Length: 279  Bit Score: 38.31  E-value: 2.00e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1720403531   3 GQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMT 35
Cdd:cd23979    94 GSGYGKDIDGHDFIMRMNQAPTVGFEADVGSRT 126
GT29_ST6GALNAC2L cd23974
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2-like; ST6GalNAc family members are ...
 3-35 7.57e-03

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2-like; ST6GalNAc family members are alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferases that catalyze an alpha-2,6-linkage between sialic acid and the N-acetylgalactosamine residues of glycochains through an 2,6-linkage, by transfering sialic acid from CMP-Sia. The ST6GalNac family belongs to glycosyltransferase family 29 (GT29).


Pssm-ID: 467702  Cd Length: 309  Bit Score: 36.65  E-value: 7.57e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1720403531   3 GQKVGEEIDHASCIWRMNNAPTKGFEEDVGYMT 35
Cdd:cd23974    98 GSRMGAEIDGHDYVFRVNGAITKGFEKDVGRRT 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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