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Conserved domains on  [gi|1720403159|ref|XP_030108280|]
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flavin-containing monooxygenase 5 isoform X3 [Mus musculus]

Protein Classification

flavin-binding monooxygenase-like family protein( domain architecture ID 1000557)

flavin-binding monooxygenase-like family protein; such as flavin-containing monooxygenases (FMOs) that catalyze the monooxygenation of a variety of substrates

EC:  1.14.13.-
Gene Ontology:  GO:0004497

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FMO-like super family cl30939
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 3-397 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


The actual alignment was detected with superfamily member pfam00743:

Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 789.74  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   3 KKRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEAPEEGRASIYQSVVINTSKEMMCFSDYPIPDHYPNY 82
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  83 MHNSQVLEYFRMYAKEFDLLKYIQFKTTVCSVKKQPDFSTSGQWQVVTECEGKQQVDVFDGVLVCTGHHTDAHLPLESFP 162
Cdd:pfam00743  81 MHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 163 GIEKFKGKYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKHGYPIDLLLSSRIMY 242
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 243 YLSRICGPSLKNNYMEKQMNQRFDHEMFGLKPKHRALSQHPTVNDDLPNRIIAGLVKVKGNVKEFTETAAVFEDGSREDG 322
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720403159 323 IDVVIFATGYSFAFPFLEDS-VKVVKNKVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGSN 397
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESlVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLC 396
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 3-397 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 789.74  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   3 KKRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEAPEEGRASIYQSVVINTSKEMMCFSDYPIPDHYPNY 82
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  83 MHNSQVLEYFRMYAKEFDLLKYIQFKTTVCSVKKQPDFSTSGQWQVVTECEGKQQVDVFDGVLVCTGHHTDAHLPLESFP 162
Cdd:pfam00743  81 MHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 163 GIEKFKGKYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKHGYPIDLLLSSRIMY 242
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 243 YLSRICGPSLKNNYMEKQMNQRFDHEMFGLKPKHRALSQHPTVNDDLPNRIIAGLVKVKGNVKEFTETAAVFEDGSREDG 322
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720403159 323 IDVVIFATGYSFAFPFLEDS-VKVVKNKVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGSN 397
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESlVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLC 396
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-394 1.44e-92

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 284.45  E-value: 1.44e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   1 MAKKRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEapeegrasiYQSVVINTSKEMMCFSDYPIPDHYP 80
Cdd:COG2072     4 TEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRDNR---------YPGLRLDTPSHLYSLPFFPNWSDDP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  81 NYMHNSQVLEYFRMYAKEFDLLKYIQFKTTVCSVKKQPDfstSGQWQVVTEcEGKQQVdvFDGVLVCTGHHTDAHLPleS 160
Cdd:COG2072    75 DFPTGDEILAYLEAYADKFGLRRPIRFGTEVTSARWDEA---DGRWTVTTD-DGETLT--ARFVVVATGPLSRPKIP--D 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 161 FPGIEKFKGKYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRvgkHGYPIDLLlssRI 240
Cdd:COG2072   147 IPGLEDFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPR---PNYDPERG---RP 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 241 MYYLSRICGPSLKNNYMEKQMNQRFDHEMFG-----LKPKHRALSQHPTVNDDLPNRIIAGLVK-VKGNVKEFTETAAVF 314
Cdd:COG2072   221 ANYLGLEAPPALNRRDARAWLRRLLRAQVKDpelglLTPDYPPGCKRPLLSTDYYEALRRGNVElVTGGIERITEDGVVF 300

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 315 EDGSREDgIDVVIFATGYSFAFPFLeDSVKVV----KNKVSLYKKVFPPNLekPTLAIIGLIQPLG--AIMPISELQGRW 388
Cdd:COG2072   301 ADGTEHE-VDVIVWATGFRADLPWL-APLDVRgrdgRSGPRAYLGVVVPGF--PNLFFLGPNSPSGhsSLTLGAERQARY 376


                  ....*.
gi 1720403159 389 ATQVFK 394
Cdd:COG2072   377 IARLIA 382
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 4-395 9.63e-42

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 152.71  E-value: 9.63e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   4 KRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEAPEEG-----------RASIYQSVVINTSKEMMCFSD 72
Cdd:PLN02172   11 QHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTPKSESDplsldptrsivHSSVYESLRTNLPRECMGYRD 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  73 YPI----------PDHYPNYMhnsQVLEYFRMYAKEFDLLKYIQFKTTVcsVKKQPdfsTSGQWQVVTECEGKQQVD-VF 141
Cdd:PLN02172   91 FPFvprfddesrdSRRYPSHR---EVLAYLQDFAREFKIEEMVRFETEV--VRVEP---VDGKWRVQSKNSGGFSKDeIF 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 142 DGVLVCTGHHTD---AHLPlesfpGIEKFKGKYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRrg 218
Cdd:PLN02172  163 DAVVVCNGHYTEpnvAHIP-----GIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIASR-- 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 219 awilnrvgkhgypidlllSSRIMYYlSRICGPSlKNNYMEKQMNqrfdhemfglkpkhralsqhpTVNDDlpnriiaglv 298
Cdd:PLN02172  236 ------------------ASESDTY-EKLPVPQ-NNLWMHSEID---------------------TAHED---------- 264

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 299 kvkGNVkeftetaaVFEDGSREDGiDVVIFATGYSFAFPFLEDS--VKVVKNKVS-LYKKVFPPNLeKPTLAIIGLiQPL 375
Cdd:PLN02172  265 ---GSI--------VFKNGKVVYA-DTIVHCTGYKYHFPFLETNgyMRIDENRVEpLYKHVFPPAL-APGLSFIGL-PAM 330

                         410       420
                  ....*....|....*....|
gi 1720403159 376 GAIMPISELQGRWATQVFKG 395
Cdd:PLN02172  331 GIQFVMFEIQSKWVAAVLSG 350
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 3-397 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 789.74  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   3 KKRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEAPEEGRASIYQSVVINTSKEMMCFSDYPIPDHYPNY 82
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  83 MHNSQVLEYFRMYAKEFDLLKYIQFKTTVCSVKKQPDFSTSGQWQVVTECEGKQQVDVFDGVLVCTGHHTDAHLPLESFP 162
Cdd:pfam00743  81 MHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 163 GIEKFKGKYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKHGYPIDLLLSSRIMY 242
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 243 YLSRICGPSLKNNYMEKQMNQRFDHEMFGLKPKHRALSQHPTVNDDLPNRIIAGLVKVKGNVKEFTETAAVFEDGSREDG 322
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720403159 323 IDVVIFATGYSFAFPFLEDS-VKVVKNKVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGSN 397
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESlVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLC 396
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-394 1.44e-92

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 284.45  E-value: 1.44e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   1 MAKKRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEapeegrasiYQSVVINTSKEMMCFSDYPIPDHYP 80
Cdd:COG2072     4 TEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRDNR---------YPGLRLDTPSHLYSLPFFPNWSDDP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  81 NYMHNSQVLEYFRMYAKEFDLLKYIQFKTTVCSVKKQPDfstSGQWQVVTEcEGKQQVdvFDGVLVCTGHHTDAHLPleS 160
Cdd:COG2072    75 DFPTGDEILAYLEAYADKFGLRRPIRFGTEVTSARWDEA---DGRWTVTTD-DGETLT--ARFVVVATGPLSRPKIP--D 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 161 FPGIEKFKGKYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRvgkHGYPIDLLlssRI 240
Cdd:COG2072   147 IPGLEDFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPR---PNYDPERG---RP 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 241 MYYLSRICGPSLKNNYMEKQMNQRFDHEMFG-----LKPKHRALSQHPTVNDDLPNRIIAGLVK-VKGNVKEFTETAAVF 314
Cdd:COG2072   221 ANYLGLEAPPALNRRDARAWLRRLLRAQVKDpelglLTPDYPPGCKRPLLSTDYYEALRRGNVElVTGGIERITEDGVVF 300

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 315 EDGSREDgIDVVIFATGYSFAFPFLeDSVKVV----KNKVSLYKKVFPPNLekPTLAIIGLIQPLG--AIMPISELQGRW 388
Cdd:COG2072   301 ADGTEHE-VDVIVWATGFRADLPWL-APLDVRgrdgRSGPRAYLGVVVPGF--PNLFFLGPNSPSGhsSLTLGAERQARY 376


                  ....*.
gi 1720403159 389 ATQVFK 394
Cdd:COG2072   377 IARLIA 382
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 4-395 9.63e-42

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 152.71  E-value: 9.63e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   4 KRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEAPEEG-----------RASIYQSVVINTSKEMMCFSD 72
Cdd:PLN02172   11 QHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTPKSESDplsldptrsivHSSVYESLRTNLPRECMGYRD 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  73 YPI----------PDHYPNYMhnsQVLEYFRMYAKEFDLLKYIQFKTTVcsVKKQPdfsTSGQWQVVTECEGKQQVD-VF 141
Cdd:PLN02172   91 FPFvprfddesrdSRRYPSHR---EVLAYLQDFAREFKIEEMVRFETEV--VRVEP---VDGKWRVQSKNSGGFSKDeIF 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 142 DGVLVCTGHHTD---AHLPlesfpGIEKFKGKYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRrg 218
Cdd:PLN02172  163 DAVVVCNGHYTEpnvAHIP-----GIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIASR-- 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 219 awilnrvgkhgypidlllSSRIMYYlSRICGPSlKNNYMEKQMNqrfdhemfglkpkhralsqhpTVNDDlpnriiaglv 298
Cdd:PLN02172  236 ------------------ASESDTY-EKLPVPQ-NNLWMHSEID---------------------TAHED---------- 264

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 299 kvkGNVkeftetaaVFEDGSREDGiDVVIFATGYSFAFPFLEDS--VKVVKNKVS-LYKKVFPPNLeKPTLAIIGLiQPL 375
Cdd:PLN02172  265 ---GSI--------VFKNGKVVYA-DTIVHCTGYKYHFPFLETNgyMRIDENRVEpLYKHVFPPAL-APGLSFIGL-PAM 330

                         410       420
                  ....*....|....*....|
gi 1720403159 376 GAIMPISELQGRWATQVFKG 395
Cdd:PLN02172  331 GIQFVMFEIQSKWVAAVLSG 350
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
58-349 1.07e-11

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 64.94  E-value: 1.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  58 SVVINTSKEMMCFSDYPipdhypnymHNSQVLEYFRMYAKEFDLLkyIQFKTTVCSVKKQpdfstSGQWQVVTEcegKQQ 137
Cdd:pfam13738  56 AISPGTSPAFTFNREHP---------SGNEYAEYLRRVADHFELP--INLFEEVTSVKKE-----DDGFVVTTS---KGT 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 138 VDVfDGVLVCTGHHtdahlpleSFPGIEKFKGKYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRR 217
Cdd:pfam13738 117 YQA-RYVIIATGEF--------DFPNKLGVPELPKHYSYVKDFHPYAGQKVVVIGGYNSAVDAALELVRKGARVTVLYRG 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 218 GAWilnrvGKHGYPIDLLLSSRImyylsricgpslknnymekqmNQRFDHEmfglkpkhralsqhptvnddlpnrIIAGL 297
Cdd:pfam13738 188 SEW-----EDRDSDPSYSLSPDT---------------------LNRLEEL------------------------VKNGK 217

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720403159 298 VKVKGN--VKEFTETAAV----FEDGSREDGIDVVIFATGYSFAFPFLEDSVKVVKNK 349
Cdd:pfam13738 218 IKAHFNaeVKEITEVDVSykvhTEDGRKVTSNDDPILATGYHPDLSFLKKGLFELDED 275
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
6-217 1.95e-06

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 48.96  E-value: 1.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   6 IAVIGAGASGLTCIKCCLEEGLEPVCFERsGDIGGlwRFQEAPEegrasIYqsvvintskemmcfsDYP-IPDHY--PNY 82
Cdd:COG0492     3 VVIIGAGPAGLTAAIYAARAGLKTLVIEG-GEPGG--QLATTKE-----IE---------------NYPgFPEGIsgPEL 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  83 MhnsqvlEYFRMYAKEFDllkyIQFKTT-VCSVKKqpdfsTSGQWQVVTECEGKQQVDVfdgVLVCTGHHtDAHLPLesf 161
Cdd:COG0492    60 A------ERLREQAERFG----AEILLEeVTSVDK-----DDGPFRVTTDDGTEYEAKA---VIIATGAG-PRKLGL--- 117

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720403159 162 PGIEKFKGK----------YFhsrdyknpveFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRR 217
Cdd:COG0492   118 PGEEEFEGRgvsycatcdgFF----------FRGKDVVVVGGGDSALEEALYLTKFASKVTLIHRR 173
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 4-218 3.24e-06

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 49.01  E-value: 3.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   4 KRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRfqeapeegrasiyqsvvintskemmcfsdYPIPDhypnym 83
Cdd:PRK12810  144 KKVAVVGSGPAGLAAADQLARAGHKVTVFERADRIGGLLR-----------------------------YGIPD------ 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  84 hnsqvleyFRMyAKEF-----DLLKY--IQFKTTVcSVKKQPDFstsgqwqvvtecegKQQVDVFDGVLVCTGHHTDAHL 156
Cdd:PRK12810  189 --------FKL-EKEVidrriELMEAegIEFRTNV-EVGKDITA--------------EELLAEYDAVFLGTGAYKPRDL 244

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159 157 PlesFPGiEKFKGKYFhSRDY-------------KNPVEFTGKRVIVIGignsGGDLAVE-----ISHTAKQVflsTRRG 218
Cdd:PRK12810  245 G---IPG-RDLDGVHF-AMDFliqntrrvlgdetEPFISAKGKHVVVIG----GGDTGMDcvgtaIRQGAKSV---TQRD 312
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-41 2.64e-05

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 45.98  E-value: 2.64e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1720403159   3 KKRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGL 41
Cdd:COG1232     1 MKRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGL 39
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 4-44 3.20e-05

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 45.89  E-value: 3.20e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1720403159   4 KRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRF 44
Cdd:PRK12769  328 KRVAIIGAGPAGLACADVLARNGVAVTVYDRHPEIGGLLTF 368
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 4-209 1.07e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 43.97  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   4 KRIAVIGAGASGLTC----IKccleEGLEPVCFERSGDIGGLwrfqeapeegrasiyqsvvintskeMMcfsdYPIPDhy 79
Cdd:COG0493   122 KKVAVVGSGPAGLAAayqlAR----AGHEVTVFEALDKPGGL-------------------------LR----YGIPE-- 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  80 pnymhnsqvleyFRM----YAKEFDLLK--YIQFKTTVcSVKKqpDFSTsgqwqvvtecegKQQVDVFDGVLVCTGHHTD 153
Cdd:COG0493   167 ------------FRLpkdvLDREIELIEalGVEFRTNV-EVGK--DITL------------DELLEEFDAVFLATGAGKP 219

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720403159 154 AHLPLesfPGiEKFKGKYF--------HSRDYKNPVEFTGKRVIVIGignsGGDLAVEISHTAK 209
Cdd:COG0493   220 RDLGI---PG-EDLKGVHSamdfltavNLGEAPDTILAVGKRVVVIG----GGNTAMDCARTAL 275
PRK07233 PRK07233
hypothetical protein; Provisional
 5-41 1.59e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 43.72  E-value: 1.59e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1720403159   5 RIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGL 41
Cdd:PRK07233    1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGL 37
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
8-49 2.85e-04

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 38.67  E-value: 2.85e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1720403159   8 VIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEAPE 49
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYRVPG 42
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
1-18 6.91e-04

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 41.64  E-value: 6.91e-04
                          10
                  ....*....|....*...
gi 1720403159   1 MAKKRIAVIGAGASGLTC 18
Cdd:COG2907     1 MARMRIAVIGSGISGLTA 18
PRK07208 PRK07208
hypothetical protein; Provisional
 1-44 7.37e-04

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 41.41  E-value: 7.37e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1720403159   1 MAKKRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGL--------WRF 44
Cdd:PRK07208    2 TNKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGIsrtvtykgNRF 53
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 3-217 7.53e-04

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 41.55  E-value: 7.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159   3 KKRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEAPeegrasiyqsvvINTSKEMMcfsdypipdhypny 82
Cdd:PRK12809  310 SEKVAVIGAGPAGLGCADILARAGVQVDVFDRHPEIGGMLTFGIPP------------FKLDKTVL-------------- 363

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403159  83 mhnSQVLEYFRMYAKEFDLlkyiqfkttVCSVKKQPDFStsgqwqvvtecegkQQVDVFDGVLVCTGHH--TDAHLPLES 160
Cdd:PRK12809  364 ---SQRREIFTAMGIDFHL---------NCEIGRDITFS--------------DLTSEYDAVFIGVGTYgmMRADLPHED 417

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720403159 161 FPG-IEKFKGKYFHSRDYKNPVE--------FTGKRVIVIGIGNSGGD-LAVEISHTAKQVFLSTRR 217
Cdd:PRK12809  418 APGvIQALPFLTAHTRQLMGLPEseeypltdVEGKRVVVLGGGDTTMDcLRTSIRLNAASVTCAYRR 484
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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