|
Name |
Accession |
Description |
Interval |
E-value |
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
2-331 |
3.95e-111 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 328.24 E-value: 3.95e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPlKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgSSNDWQLDPTELA 81
Cdd:COG0436 89 DP-DEILVTNGAKEALALALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLD----------EENGFLPDPEALE 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKS 161
Cdd:COG0436 158 AAITPRTKAIVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVSILSLPGLKDRTIVINSFSKS 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 162 FSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQlpqamglNRDHMIQSLQSVG 241
Cdd:COG0436 238 YAMTGWRIGYAVGPPELIAALLKLQSNLTSCAPTPAQYAAAAALEGPQDYVEEMRAEYRR-------RRDLLVEGLNEIG 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 242 LKPLIPQGSYFLIADISDFKSSmpdlpgamdepyDTRFAKWMIKNKGLSAIPVSTFYSQPhhkdfDHYIRFCFVKDKATL 321
Cdd:COG0436 311 LSVVKPEGAFYLFADVPELGLD------------SEEFAERLLEEAGVAVVPGSAFGPAG-----EGYVRISYATSEERL 373
|
330
....*....|
gi 1720400629 322 QAMDKRLCSW 331
Cdd:COG0436 374 EEALERLARF 383
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
2-333 |
4.07e-106 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 315.38 E-value: 4.07e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVslRLSPaPkgqlgssnDWQLDPTELA 81
Cdd:PRK08912 85 DPETEVMVTSGATEALAAALLALVEPGDEVVLFQPLYDAYLPLIRRAGGVPRLV--RLEP-P--------HWRLPRAALA 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKS 161
Cdd:PRK08912 154 AAFSPRTKAVLLNNPLNPAGKVFPREELALLAEFCQRHDAVAICDEVWEHVVFDGRRHIPLMTLPGMRERTVKIGSAGKI 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 162 FSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAqcfereqQHFGQPSSYFLQLPQAMGLNRDHMIQSLQSVG 241
Cdd:PRK08912 234 FSLTGWKVGFVCAAPPLLRVLAKAHQFLTFTTPPNLQAAVA-------YGLGKPDDYFEGMRADLARSRDRLAAGLRRIG 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 242 LKPLIPQGSYFLIADISdfkssmpDLPGAMDepyDTRFAKWMIKNKGLSAIPVSTFYSQphhKDFDHYIRFCFVKDKATL 321
Cdd:PRK08912 307 FPVLPSQGTYFLTVDLA-------PLGLAED---DVAFCRRLVEEAGVAAIPVSAFYEE---DPVTSVVRFCFAKRDATL 373
|
330
....*....|..
gi 1720400629 322 QAMDKRLCSWKG 333
Cdd:PRK08912 374 DEAVERLAAARR 385
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
2-333 |
2.81e-94 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 285.39 E-value: 2.81e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlGSSNDWQLDPTELA 81
Cdd:PRK07777 83 DPDTEVLVTVGATEAIAAAVLGLVEPGDEVLLIEPYYDSYAAVIAMAGAHRVPVPLV---------PDGRGFALDLDALR 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKS 161
Cdd:PRK07777 154 AAVTPRTRALIVNSPHNPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARHLPLATLPGMRERTVTISSAAKT 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 162 FSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQqhfgqpsSYFLQLPQAMGLNRDHMIQSLQSVG 241
Cdd:PRK07777 234 FNVTGWKIGWACGPAPLIAAVRAAKQYLTYVGGAPFQPAVAHALDHED-------AWVAALRDSLQAKRDRLAAGLAEAG 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 242 LKPLIPQGSYFLIADISDFkssmpdlpGAMDepyDTRFAKWMIKNKGLSAIPVSTFYSqpHHKDFDHYIRFCFVKDKATL 321
Cdd:PRK07777 307 FEVHDSAGTYFLCADPRPL--------GYDD---GTEFCRALPERVGVAAIPMSVFYD--PADAWNHLVRFAFCKRDDTL 373
|
330
....*....|..
gi 1720400629 322 QAMDKRLCSWKG 333
Cdd:PRK07777 374 DEAIRRLRALRG 385
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
2-329 |
1.03e-89 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 273.72 E-value: 1.03e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspAPkgqlGSSNDWQldptELA 81
Cdd:PRK09082 89 DADSEITVTAGATEALFAAILALVRPGDEVIVFDPSYDSYAPAIELAGGRAVRVALQ---PP----DFRVDWQ----RFA 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKS 161
Cdd:PRK09082 158 AAISPRTRLIILNTPHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIVFDGAGHASVLRHPELRERAFVVSSFGKT 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 162 FSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHfgqpssyFLQLPQAMGLNRDHMIQSLQSVG 241
Cdd:PRK09082 238 YHVTGWKVGYCVAPAALSAEFRKVHQYNTFTVNTPAQLALADYLRAEPEH-------YLELPAFYQAKRDRFRAALANSR 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 242 LKPLIPQGSYFLIADIsdfkSSMPDLPgamdepyDTRFAKWMIKNKGLSAIPVSTFYSQPhhkdFDH-YIRFCFVKDKAT 320
Cdd:PRK09082 311 FKLLPCEGTYFQLVDY----SAISDLD-------DVEFCQWLTREHGVAAIPLSVFYADP----FPHrLVRLCFAKQEET 375
|
....*....
gi 1720400629 321 LQAMDKRLC 329
Cdd:PRK09082 376 LDAAAERLC 384
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
1-328 |
1.17e-84 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 261.72 E-value: 1.17e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspAPkgqlgssnDWQLDPTEL 80
Cdd:PLN00175 112 VDPEKEVTVTSGCTEAIAATILGLINPGDEVILFAPFYDSYEATLSMAGAKIKTVTLR---PP--------DFAVPEDEL 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 81 ASKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGhQHISIASLPGMWERTLTIGSAGK 160
Cdd:PLN00175 181 KAAFTSKTRAILINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFEG-DHISMASLPGMYERTVTMNSLGK 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 161 SFSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEreqqhfgQPSSYFLQLPQAMGLNRDHMIQSLQSV 240
Cdd:PLN00175 260 TFSLTGWKIGWAIAPPHLTWGVRQAHSFLTFATATPMQWAAVAALR-------APESYYEELKRDYSAKKDILVEGLKEV 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 241 GLKPLIPQGSYFLIADISDFkssmpdlpgAMDEpyDTRFAKWMIKNKGLSAIPVSTFYSQPhhKDFDHYIRFCFVKDKAT 320
Cdd:PLN00175 333 GFKVYPSSGTYFVMVDHTPF---------GFEN--DIAFCEYLIEEVGVAAIPPSVFYLNP--EDGKNLVRFAFCKDEET 399
|
....*...
gi 1720400629 321 LQAMDKRL 328
Cdd:PLN00175 400 LRAAVERM 407
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
6-328 |
1.13e-80 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 249.18 E-value: 1.13e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgSSNDWQLDPTELASKFT 85
Cdd:cd00609 61 EIVVTNGAQEALSLLLRALLNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLD----------EEGGFLLDLELLEAAKT 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 86 PRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHiSIASLPGMWERTLTIGSAGKSFSAT 165
Cdd:cd00609 131 PKTKLLYLNNPNNPTGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPP-PALALLDAYERVIVLRSFSKTFGLP 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 166 GWKVGWVMGPDN-IMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQlpqamglNRDHMIQSLQSVG-LK 243
Cdd:cd00609 210 GLRIGYLIAPPEeLLERLKKLLPYTTSGPSTLSQAAAAAALDDGEEHLEELRERYRR-------RRDALLEALKELGpLV 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 244 PLIPQGSYFLiadisdfkssMPDLPgamdEPYDTRFAKWMIKNKGLSAIPVSTFYSQPhhkdfDHYIRFCFVKDKATLQA 323
Cdd:cd00609 283 VVKPSGGFFL----------WLDLP----EGDDEEFLERLLLEAGVVVRPGSAFGEGG-----EGFVRLSFATPEEELEE 343
|
....*
gi 1720400629 324 MDKRL 328
Cdd:cd00609 344 ALERL 348
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
5-328 |
1.44e-80 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 250.43 E-value: 1.44e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 5 KNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVslrlspapkgQLGSSNDWQLDPTELASKF 84
Cdd:PRK05764 92 SQVIVTTGAKQALYNAFMALLDPGDEVIIPAPYWVSYPEMVKLAGGVPVFV----------PTGEENGFKLTVEQLEAAI 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 85 TPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASL-PGMWERTLTIGSAGKSFS 163
Cdd:PRK05764 162 TPKTKALILNSPSNPTGAVYSPEELEAIADVAVEHDIWVLSDEIYEKLVYDGAEFTSIASLsPELRDRTITVNGFSKAYA 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 164 ATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQ-AAVA------QCFEREQQHFGQpssyflqlpqamglNRDHMIQS 236
Cdd:PRK05764 242 MTGWRLGYAAGPKELIKAMSKLQSHSTSNPTSIAQyAAVAalngpqDEVEEMRQAFEE--------------RRDLMVDG 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 237 LQSV-GLKPLIPQGSYFLIADISDFkssmpdlpGAMDEPYDTRFAKWMIKNKGLSAIPVSTFYSqphhkdfDHYIRFCFV 315
Cdd:PRK05764 308 LNEIpGLECPKPEGAFYVFPNVSKL--------LGKSITDSLEFAEALLEEAGVAVVPGIAFGA-------PGYVRLSYA 372
|
330
....*....|....
gi 1720400629 316 KDKATLQ-AMDkRL 328
Cdd:PRK05764 373 TSLEDLEeGLE-RI 385
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
2-330 |
7.03e-70 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 222.74 E-value: 7.03e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVfvSLRLSPapkgqlgssNDWQLDPTELA 81
Cdd:PRK12414 88 DPASEVTVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPV--AIKLSP---------EDFRVNWDEVA 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKS 161
Cdd:PRK12414 157 AAITPRTRMIIVNTPHNPSATVFSAADLARLAQLTRNTDIVILSDEVYEHVVFDGARHHSMARHRELAERSVIVSSFGKS 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 162 FSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAqcfereqQHFGQPSSYfLQLPQAMGLNRDHMIQSLQSVG 241
Cdd:PRK12414 237 YHVTGWRVGYCLAPAELMDEIRKVHQFMVFSADTPMQHAFA-------EALAEPASY-LGLGAFYQRKRDLLARELAGSR 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 242 LKPLIPQGSYFLIADISDFKssmpdlpgamDEPyDTRFAKWMIKNKGLSAIPVSTFYSQPHHKDFdhyIRFCFVKDKATL 321
Cdd:PRK12414 309 FELLPSEGSFFMLARFRHFS----------DES-DSDFVLRLIRDARVATIPLSAFYTDGTDTGL---IRLSFSKDDATL 374
|
....*....
gi 1720400629 322 QAMDKRLCS 330
Cdd:PRK12414 375 VEGARRLCS 383
|
|
| GntC_guanitoxin |
NF041364 |
guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC; |
6-326 |
2.28e-61 |
|
guanitoxin biosynthesis PLP-dependent (S)-gamma-hydroxy-L-arginine cyclodehydratase GntC;
Pssm-ID: 469255 Cd Length: 354 Bit Score: 199.87 E-value: 2.28e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRLSpapkgqlgsSNDWQLDPTELASKFT 85
Cdd:NF041364 62 QVLVTTGASEALFLYFHALLEPGDEVVVPVPAFQSLYEVPELLGGRVRPLPLSPE---------NQGFRPDLEALRSLIT 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 86 PRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKSFSAT 165
Cdd:NF041364 133 PRTRAIVINSPNNPTGAVMTEAELEAILEIASRHGLIVLADEHYRFLPYDDGKHVSPSLYPGLSERVIALGSFSKTYGMT 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 166 GWKVGWVMGPDNIMKHLRTVHQNSIfHCPTQ-AQAAVAQCFEREQQhfgqpsSYFLQLPQAMGLNRDHMIQSLQSV-GLK 243
Cdd:NF041364 213 GLRVGWLIGPKELIGAILKFKDYTT-HCAPSiSQYAALEALEQGPQ------ERVKGWVRENVRRRDALVERLERLiGWV 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 244 PLiPQGSYFLIADISDfkssmpDLPGAmdepydtRFAKWMIKNKGLSAIPVSTFysQPHHKDfdhYIRFCF-VKDKATLQ 322
Cdd:NF041364 286 CE-PEGGFYAFPKLKD------GLPSA-------AFAEELLEKAGVVVLPGSAF--GRPGEG---YFRIGFaNSPTRLKE 346
|
....
gi 1720400629 323 AMDK 326
Cdd:NF041364 347 ALER 350
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
2-258 |
2.35e-61 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 200.35 E-value: 2.35e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVslrlspapkgQLGSSNDWQLDPTELA 81
Cdd:PRK07682 79 DPNDEIIVTVGASQALDVAMRAIINPGDEVLIVEPSFVSYAPLVTLAGGVPVPV----------ATTLENEFKVQPAQIE 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGhQHISIASLPGMWERTLTIGSAGKS 161
Cdd:PRK07682 149 AAITAKTKAILLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDE-AYTSFASIKGMRERTILISGFSKG 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 162 FSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQlpqamglNRDHMIQSLQSVG 241
Cdd:PRK07682 228 FAMTGWRLGFIAAPVYFSEAMLKIHQYSMMCAPTMAQFAALEALRAGNDDVIRMRDSYRK-------RRNFFVTSFNEIG 300
|
250
....*....|....*..
gi 1720400629 242 LKPLIPQGSYFLIADIS 258
Cdd:PRK07682 301 LTCHVPGGAFYAFPSIS 317
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
4-328 |
1.09e-48 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 167.59 E-value: 1.09e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 4 LKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVslrlspapkgQLGSSNDWQLDPTELASK 83
Cdd:PRK06348 89 RNEIMATVGACHGMYLALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIIL----------ETYEEDGFQINVKKLEAL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 84 FTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDgHQHISIASLPGMWERTLTIGSAGKSFS 163
Cdd:PRK06348 159 ITSKTKAIILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFY-EDFVPMATLAGMPERTITFGSFSKDFA 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 164 ATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQ-AAVAQCFEREQqhfgqpssyfLQlPQAMGLNRDHMIQSLQSVGL 242
Cdd:PRK06348 238 MTGWRIGYVIAPDYIIETAKIINEGICFSAPTISQrAAIYALKHRDT----------IV-PLIKEEFQKRLEYAYKRIES 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 243 KP----LIPQGSYFLIADISDF-KSSMPdlpgamdepydtrFAKWMIKNKGLSAIPVSTFysqphHKDFDHYIRFCFVKD 317
Cdd:PRK06348 307 IPnlslHPPKGSIYAFINIKKTgLSSVE-------------FCEKLLKEAHVLVIPGKAF-----GESGEGYIRLACTVG 368
|
330
....*....|.
gi 1720400629 318 KATLQAMDKRL 328
Cdd:PRK06348 369 IEVLEEAFNRI 379
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
2-297 |
1.27e-47 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 164.90 E-value: 1.27e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgsSNDWQLDPTELA 81
Cdd:PRK07683 87 SPESEIIVTIGASEAIDIAFRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFIDTR-----------STGFRLTAEALE 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGhQHISIASLPGMWERTLTIGSAGKS 161
Cdd:PRK07683 156 NAITEKTRCVVLPYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQ-PHTSIAHFPEMREKTIVINGLSKS 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 162 FSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHfgqpssyflqlPQAM----GLNRDHMIQSL 237
Cdd:PRK07683 235 HSMTGWRIGFLFAPSYLAKHILKVHQYNVTCASSISQYAALEALTAGKDD-----------AKMMrhqyKKRRDYVYNRL 303
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 238 QSVGLKPLIPQGSYFLIADISDFKSSMPDlpgamdepydtrFAKWMIKNKGLSAIPVSTF 297
Cdd:PRK07683 304 ISMGLDVEKPTGAFYLFPSIGHFTMSSFD------------FALDLVEEAGLAVVPGSAF 351
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
2-314 |
5.34e-47 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 162.09 E-value: 5.34e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgSSNDWQLDPTELA 81
Cdd:pfam00155 61 DREAAVVFGSGAGANIEALIFLLANPGDAILVPAPTYASYIRIARLAGGEVVRYPLY----------DSNDFHLDFDALE 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASL--PGMWerTLTIGSAG 159
Cdd:pfam00155 131 AALKEKPKVVLHTSPHNPTGTVATLEELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRALlaEGPN--LLVVGSFS 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 160 KSFSATGWKVGWVMGPDNIMKHLRTVHQNSIFhcPTQAQAAVAQCFEREQQHfgqpSSYFLQLPQAMGLNRDHMIQSLQS 239
Cdd:pfam00155 209 KAFGLAGWRVGYILGNAAVISQLRKLARPFYS--STHLQAAAAAALSDPLLV----ASELEEMRQRIKERRDYLRDGLQA 282
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720400629 240 VGLKPLIPQGSYFLIADIsdfkssmpdlpgamDEPYDTRFAKWMIKNKGLSAIPVSTFYSQPHhkdfdhyIRFCF 314
Cdd:pfam00155 283 AGLSVLPSQAGFFLLTGL--------------DPETAKELAQVLLEEVGVYVTPGSSPGVPGW-------LRITV 336
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
6-326 |
6.93e-45 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 157.73 E-value: 6.93e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgSSNDWQLDPTELASKFT 85
Cdd:PRK08361 95 NVIVTAGAYEATYLAFESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLR----------EENEFQPDPDELLELIT 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 86 PRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHIS-IASLPgmwERTLTIGSAGKSFSA 164
Cdd:PRK08361 165 KRTRMIVINYPNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAKHYPmIKYAP---DNTILANSFSKTFAM 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 165 TGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFeREQQHFGQPSsyflQLPQAMGLNRDHMIQSLQSV-GLK 243
Cdd:PRK08361 242 TGWRLGFVIAPEQVIKDMIKLHAYIIGNVASFVQIAGIEAL-RSKESWKAVE----EMRKEYNERRKLVLKRLKEMpHIK 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 244 PLIPQGSYFLIADISDFKSSMPDlpgamdepydtrFAKWMIKNKGLSAIPVSTFysqphHKDFDHYIRFCFVKDKATL-Q 322
Cdd:PRK08361 317 VFEPKGAFYVFANIDETGMSSED------------FAEWLLEKARVVVIPGTAF-----GKAGEGYIRISYATSKEKLiE 379
|
....
gi 1720400629 323 AMDK 326
Cdd:PRK08361 380 AMER 383
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
2-331 |
7.26e-44 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 154.72 E-value: 7.26e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRLSPapkgqlgssNDWQLDPTELA 81
Cdd:PRK06108 82 TPPERIAVTSSGVQALMLAAQALVGPGDEVVAVTPLWPNLVAAPKILGARVVCVPLDFGG---------GGWTLDLDRLL 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGH----QHISIASlPGmwERTLTIGS 157
Cdd:PRK06108 153 AAITPRTRALFINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGgrapSFLDIAE-PD--DRIIFVNS 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 158 AGKSFSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQ-AAVAQCfeREQQHFGQpssyflQLPQAMGLNRDHMIQS 236
Cdd:PRK06108 230 FSKNWAMTGWRLGWLVAPPALGQVLEKLIEYNTSCVAQFVQrAAVAAL--DEGEDFVA------ELVARLRRSRDHLVDA 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 237 LQSV-GLKPLIPQGSYFLiadisdfkssMPDLPGAMDEpydTRFAKWMIKNKGLSAIPVSTFysQPHHKDFdhyIRFCFV 315
Cdd:PRK06108 302 LRALpGVEVAKPDGAMYA----------FFRIPGVTDS---LALAKRLVDEAGLGLAPGTAF--GPGGEGF---LRWCFA 363
|
330
....*....|....*.
gi 1720400629 316 KDKATLQAMDKRLCSW 331
Cdd:PRK06108 364 RDPARLDEAVERLRRF 379
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
2-328 |
4.12e-42 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 150.26 E-value: 4.12e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgsSNDWQLDPTELA 81
Cdd:PRK07309 89 APENEILVTIGATEALSASLTAILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTT-----------ENDFVLTPEMLE 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPR---TKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIAS-LPgmwERTLTIGS 157
Cdd:PRK07309 158 KAILEQgdkLKAVILNYPANPTGVTYSREQIKALADVLKKYDIFVISDEVYSELTYTGEPHVSIAEyLP---DQTILING 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 158 AGKSFSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFeREQQHFGQPssyflqLPQAMGLNRDHMIQSL 237
Cdd:PRK07309 235 LSKSHAMTGWRIGLIFAPAEFTAQLIKSHQYLVTAATTMAQFAAVEAL-TNGKDDALP------MKKEYIKRRDYIIEKM 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 238 QSVGLKPLIPQGSYFLIADISDfkssmpdlpgamDEPYDTR-FAKWMIKNKGLSAIPVSTFysqphHKDFDHYIRFCFVK 316
Cdd:PRK07309 308 TDLGFKIIKPDGAFYIFAKIPA------------GYNQDSFkFLQDFARKKAVAFIPGAAF-----GPYGEGYVRLSYAA 370
|
330
....*....|..
gi 1720400629 317 DKATLQAMDKRL 328
Cdd:PRK07309 371 SMETIKEAMKRL 382
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
7-253 |
8.31e-39 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 141.80 E-value: 8.31e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 7 VLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVslrlspapkgQLGSSNDWQLDPTELASKFTP 86
Cdd:PRK06107 96 ITVGGGAKQAIFLALMATLEAGDEVIIPAPYWVSYPDMVLANDGTPVIV----------ACPEEQGFKLTPEALEAAITP 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 87 RTKILVLNTPNNPLGKVFSKKELELVAALCQQH-DVLCFSDEVYQWLVYDGHQHISI-ASLPGMWERTLTIGSAGKSFSA 164
Cdd:PRK06107 166 RTRWLILNAPSNPTGAVYSRAELRALADVLLRHpHVLVLTDDIYDHIRFDDEPTPHLlAAAPELRDRVLVTNGVSKTYAM 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 165 TGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQlpqamglNRDHMIQSLQSV-GLK 243
Cdd:PRK06107 246 TGWRIGYAAGPADLIAAINKLQSQSSSCPSSISQAAAAAALNGDQSFVTESVAVYKQ-------RRDYALALLNAIpGLS 318
|
250
....*....|
gi 1720400629 244 PLIPQGSYFL 253
Cdd:PRK06107 319 CLVPDGAFYL 328
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
6-325 |
2.18e-38 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 140.76 E-value: 2.18e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGgrpvfVSLRLSPAPkgqlgSSNDWQLDPTE-LASKF 84
Cdd:PRK07568 90 EILITNGGSEAILFAMMAICDPGDEILVPEPFYANYNGFATSAG-----VKIVPVTTK-----IEEGFHLPSKEeIEKLI 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 85 TPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKSFSA 164
Cdd:PRK07568 160 TPKTKAILISNPGNPTGVVYTKEELEMLAEIAKKHDLFLISDEVYREFVYDGLKYTSALSLEGLEDRVIIIDSVSKRYSA 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 165 TGWKVGWVmgpdnIMKHlRTVHQNSIFHC------PTQAQAAVAQCFEreqqhfgQPSSYFLQLPQAMGLNRDHMIQSLQ 238
Cdd:PRK07568 240 CGARIGCL-----ISKN-KELIAAAMKLCqarlspPTLEQIGAAALLD-------TPESYFDEVREEYKKRRDILYEELN 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 239 SV-GLKPLIPQGSYFLIAdisdfkssmpDLPgaMDEPYDtrFAKWMIK-----NKGLSAIPVSTFYSQPHH-KDfdhYIR 311
Cdd:PRK07568 307 KIpGVVCEKPKGAFYIIA----------KLP--VDDAED--FAKWLLTdfnynGETVMVAPASGFYATPGLgKN---EIR 369
|
330
....*....|....*
gi 1720400629 312 FCFVKDKATLQ-AMD 325
Cdd:PRK07568 370 IAYVLNEEDLKrAME 384
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
3-328 |
3.80e-36 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 134.42 E-value: 3.80e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 3 PLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVslrlsPApkgqlGSSNDWQLDPTELAS 82
Cdd:PRK07337 89 APERIVVTAGASAALLLACLALVERGDEVLMPDPSYPCNRHFVAAAEGRPVLV-----PS-----GPAERFQLTAADVEA 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 83 KFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIAslpgMWERTLTIGSAGKSF 162
Cdd:PRK07337 159 AWGERTRGVLLASPSNPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALS----LGDDVITINSFSKYF 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 163 SATGWKVGWVMGPDNIMKHLRTVHQNsIFHCP-TQAQAAVAQCFEreqqhfgqPSSY--FLQLPQAMGLNRDHMIQSLQS 239
Cdd:PRK07337 235 NMTGWRLGWLVVPEALVGTFEKLAQN-LFICAsALAQHAALACFE--------PDTLaiYERRRAEFKRRRDFIVPALES 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 240 VGLK-PLIPQGSYFLIADISdfKSSMPDLPGAMDepydtrFAKWMIKNKGLSAIPVSTFysQPHHKdfDHYIRFCFVKDK 318
Cdd:PRK07337 306 LGFKvPVMPDGAFYVYADCR--GVAHPAAGDSAA------LTQAMLHDAGVVLVPGRDF--GPHAP--RDYIRLSYATSM 373
|
330
....*....|
gi 1720400629 319 ATLQAMDKRL 328
Cdd:PRK07337 374 SRLEEAVARL 383
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
1-297 |
1.36e-35 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 132.89 E-value: 1.36e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVslrlsPAPKGqlgssndWQLDPTEL 80
Cdd:PRK05957 86 LNNEQAIVVTAGSNMAFMNAILAITDPGDEIILNTPYYFNHEMAITMAGCQPILV-----PTDDN-------YQLQPEAI 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 81 ASKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGK 160
Cdd:PRK05957 154 EQAITPKTRAIVTISPNNPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDGVKHFSPGSIPGSGNHTISLYSLSK 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 161 SFSATGWKVGWVMGPDNIMKHLRTVhQNSIFHCP---TQaQAAVAQcfereqqhFGQPSSYFLQ-LPQAMGLnRDHMIQS 236
Cdd:PRK05957 234 AYGFASWRIGYMVIPIHLLEAIKKI-QDTILICPpvvSQ-YAALGA--------LQVGKSYCQQhLPEIAQV-RQILLKS 302
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720400629 237 LQSVGLKPLI--PQGS-YFLI---ADISDFKssmpdlpgamdepydtrFAKWMIKNKGLSAIPVSTF 297
Cdd:PRK05957 303 LGQLQDRCTLhpANGAfYCFLkvnTDLNDFE-----------------LVKQLIREYRVAVIPGTTF 352
|
|
| MalY |
COG1168 |
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ... |
16-162 |
2.11e-34 |
|
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];
Pssm-ID: 440782 Cd Length: 387 Bit Score: 129.44 E-value: 2.11e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 16 ALFTAFQALVDEGDEVIIIEPAfncYEPMTMM---AGGRPVFVSLRLSPapkgqlgssNDWQLDPTELASKFTPRTKILV 92
Cdd:COG1168 99 GLALAIRAFTEPGDGVLIQTPV---YPPFFKAienNGRELVENPLILED---------GRYRIDFDDLEAKLDPGVKLLL 166
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720400629 93 LNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASL-PGMWERTLTIGSAGKSF 162
Cdd:COG1168 167 LCNPHNPTGRVWTREELERLAELCERHDVLVISDEIHADLVLPGHKHTPFASLsEEAADRTITLTSPSKTF 237
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
7-328 |
1.68e-33 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 127.09 E-value: 1.68e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 7 VLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLrlspapkgqlGSSNDWQLDPTELASKFTP 86
Cdd:PRK08960 95 ILVTPGGSGALLLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPV----------GPDSRYQLTPALVERHWNA 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 87 RTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDghqhISIASLPGMWERTLTIGSAGKSFSATG 166
Cdd:PRK08960 165 DTVGALVASPANPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYG----VDAASVLEVDDDAFVLNSFSKYFGMTG 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 167 WKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQqhfgqpSSYFLQLPQAMGLNRDHMIQSLQSVGLK-PL 245
Cdd:PRK08960 241 WRLGWLVAPPAAVPELEKLAQNLYISASTPAQHAALACFEPET------LAILEARRAEFARRRDFLLPALRELGFGiAV 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 246 IPQGSYFLIADISDFKssmpdlpgamDEPYdtRFAKWMIKNKGLSAIPVSTFysqPHHKDfDHYIRFCFVKDKATLQAMD 325
Cdd:PRK08960 315 EPQGAFYLYADISAFG----------GDAF--AFCRHFLETEHVAFTPGLDF---GRHQA-GQHVRFAYTQSLPRLQEAV 378
|
...
gi 1720400629 326 KRL 328
Cdd:PRK08960 379 ERI 381
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
20-175 |
4.06e-32 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 123.77 E-value: 4.06e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 20 AFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFvsLRLSPapkgqlgsSNDWQLDPTELASKFTPRTKILVLNTPNNP 99
Cdd:PRK09265 111 AMQALLNNGDEVLVPAPDYPLWTAAVSLSGGKPVH--YLCDE--------EAGWFPDLDDIRSKITPRTKAIVIINPNNP 180
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720400629 100 LGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASL-PGMWerTLTIGSAGKSFSATGWKVGWVM--GP 175
Cdd:PRK09265 181 TGAVYSKELLEEIVEIARQHNLIIFADEIYDKILYDGAVHISIASLaPDLL--CVTFNGLSKAYRVAGFRVGWMVlsGP 257
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
6-253 |
3.27e-31 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 121.07 E-value: 3.27e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgsSNDWQLDPTELASKFT 85
Cdd:PRK06836 98 HIVMTCGAAGALNVALKAILNPGDEVIVFAPYFVEYRFYVDNHGGKLVVVPTD-----------TDTFQPDLDALEAAIT 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 86 PRTKILVLNTPNNPLGKVFSKKELELVAALCQQ------HDVLCFSDEVYQWLVYDGhqhISIASLPGMWERTLTIGSAG 159
Cdd:PRK06836 167 PKTKAVIINSPNNPTGVVYSEETLKALAALLEEkskeygRPIYLISDEPYREIVYDG---AEVPYIFKYYDNSIVVYSFS 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 160 KSFSATGWKVGWVM------GPDNIMKHLrtVHQNSI--FHC-PTQAQAAVAQCfereqqhFGQPS--SYFLQlpqamgl 228
Cdd:PRK06836 244 KSLSLPGERIGYIAvnpemeDADDLVAAL--VFANRIlgFVNaPALMQRVVAKC-------LDATVdvSIYKR------- 307
|
250 260
....*....|....*....|....*
gi 1720400629 229 NRDHMIQSLQSVGLKPLIPQGSYFL 253
Cdd:PRK06836 308 NRDLLYDGLTELGFECVKPQGAFYL 332
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
5-261 |
3.61e-31 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 121.07 E-value: 3.61e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 5 KNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPV-FVSLRLspapkgqlgssNDWQLDPTELASK 83
Cdd:PRK08363 94 DDVRVTAAVTEALQLIFGALLDPGDEILIPGPSYPPYTGLVKFYGGVPVeYRTIEE-----------EGWQPDIDDIRKK 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 84 FTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGhQHISIASLPGMwERTLTIGSAGKSFS 163
Cdd:PRK08363 163 ITEKTKAIAVINPNNPTGALYEKKTLKEILDIAGEHDLPVISDEIYDLMTYEG-KHVSPGSLTKD-VPVIVMNGLSKVYF 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 164 ATGWKVGWV--MGPDNIMKHLRTVHQN--SIFHCP-TQAQAAVAQCFEREQQHFgqpSSYFLQLPQamglNRDHMIQSLQ 238
Cdd:PRK08363 241 ATGWRLGYIyfVDPEGKLAEVREAIDKlaRIRLCPnTPAQFAAIAGLTGPMDYL---EEYMKKLKE----RRDYIYKRLN 313
|
250 260
....*....|....*....|....
gi 1720400629 239 SV-GLKPLIPQGSYFLIADISDFK 261
Cdd:PRK08363 314 EIpGISTTKPQGAFYIFPRIEEGP 337
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
5-297 |
1.11e-29 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 117.19 E-value: 1.11e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 5 KNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTmmaggRPVFVSLRLSpapkgQLGSSNDWQLDPTELASKF 84
Cdd:TIGR01264 96 DDVVLCSGCSHAIEMCIAALANAGQNILVPRPGFPLYETLA-----ESMGIEVKLY-----NLLPDKSWEIDLKQLESLI 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 85 TPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERtLTIGSAGKSFSA 164
Cdd:TIGR01264 166 DEKTAALIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFSGATFEPLASLSSTVPI-LSCGGLAKRWLV 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 165 TGWKVGWVMGPD------NIMKHLRTVHQNSIFHCpTQAQAAVAQCFEReqqhfgQPSSYFLQLPQAMGLNRDHMIQSL- 237
Cdd:TIGR01264 245 PGWRLGWIIIHDrrgilrDIRDGLVKLSQRILGPC-TIVQGALPSILLR------TPQEYFDGTLSVLESNAMLCYGALa 317
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720400629 238 QSVGLKPLIPQGSYFLIADIS-----DFKSsmpdlpgamdepyDTRFAKWMIKNKGLSAIPVSTF 297
Cdd:TIGR01264 318 AVPGLRPVMPSGAMYMMVGIEmehfpEFKN-------------DVEFTERLVAEQSVFCLPGSCF 369
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
6-262 |
1.23e-29 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 117.19 E-value: 1.23e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgSSNDWQLDPTELASKFT 85
Cdd:PTZ00433 106 NVVLCSGVSHAILMALTALCDEGDNILVPAPGFPHYETVCKAYGIEMRFYNCR----------PEKDWEADLDEIRRLVD 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 86 PRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERtLTIGSAGKSFSAT 165
Cdd:PTZ00433 176 DRTKALIMTNPSNPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAGMVFNGATFTSVADFDTTVPR-VILGGTAKNLVVP 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 166 GWKVGW--VMGPDN----IMKHLRTVHQNSIFHCpTQAQAAVAQCFEReqqhfgQPSSYFLQLPQ-----AMGLNRdhMI 234
Cdd:PTZ00433 255 GWRLGWllLVDPHGnggdFLDGMKRLGMLVCGPC-SVVQAALGEALLN------TPQEHLEQIVAkleegAMVLYN--HI 325
|
250 260 270
....*....|....*....|....*....|
gi 1720400629 235 QslQSVGLKPLIPQGSYFLIA--DISDFKS 262
Cdd:PTZ00433 326 G--ECIGLSPTMPRGSMFLMSrlDLEKFRD 353
|
|
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
6-314 |
2.12e-29 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 117.24 E-value: 2.12e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPafnCYEPMTMMAGGRpvfvSLRLSPAPKGQLGssndwqLDPTELASKF- 84
Cdd:COG1167 172 QILITSGAQQALDLALRALLRPGDTVAVESP---TYPGALAALRAA----GLRLVPVPVDEDG------LDLDALEAALr 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 85 TPRTKILVLnTPN--NPLGKVFS---KKELelvAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMwERTLTIGSAG 159
Cdd:COG1167 239 RHRPRAVYV-TPShqNPTGATMSlerRRAL---LELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAP-GRVIYIGSFS 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 160 KSFSAtGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFerEQQHFGQpssYFLQLPQAMGLNRDHMIQSLQS 239
Cdd:COG1167 314 KTLAP-GLRLGYLVAPGRLIERLARLKRATDLGTSPLTQLALAEFL--ESGHYDR---HLRRLRREYRARRDLLLAALAR 387
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720400629 240 V---GLKPLIPQGSYFLIAdisdfkssmpDLPGAMDepyDTRFAKWMIKnKGLSAIPVSTFYSQPHhkdFDHYIRFCF 314
Cdd:COG1167 388 HlpdGLRVTGPPGGLHLWL----------ELPEGVD---AEALAAAALA-RGILVAPGSAFSADGP---PRNGLRLGF 448
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
6-254 |
9.33e-29 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 113.30 E-value: 9.33e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgssNDWQLDPTELASKFT 85
Cdd:COG0079 67 QVLVGNGSDELIQLLARAFLGPGDEVLVPEPTFSEYPIAARAAGAEVVEVPLD------------EDFSLDLDALLAAIT 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 86 PRTKILVLNTPNNPLGKVFSKKELELVAALCQQhDVLCFSDEVYqwlvYD-GHQHISIASLPGMWERTLTIGSAGKSFSA 164
Cdd:COG0079 135 ERTDLVFLCNPNNPTGTLLPREELEALLEALPA-DGLVVVDEAY----AEfVPEEDSALPLLARYPNLVVLRTFSKAYGL 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 165 TGWKVGWVMGPDNIMKHLRTVHQnsIFHCPTQAQAAVAQCFEREQqhfgqpssYFLQ----LPQAmglnRDHMIQSLQSV 240
Cdd:COG0079 210 AGLRLGYAIASPELIAALRRVRG--PWNVNSLAQAAALAALEDRA--------YLEEtrarLRAE----RERLAAALRAL 275
|
250
....*....|....
gi 1720400629 241 GLKPLIPQGSYFLI 254
Cdd:COG0079 276 GLTVYPSQANFVLV 289
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
1-328 |
1.39e-28 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 114.13 E-value: 1.39e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgSSNDWQLDPTEL 80
Cdd:PRK07681 90 LNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLK----------KENDFLPDLELI 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 81 ASKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGK 160
Cdd:PRK07681 160 PEEIADKAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSK 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 161 SFSATGWKVGWVMGPDNIMKHLRTVHQN---SIFhCPTQAQAAVAQcfeREQQHFGQPSSYFLQlpqamgLNRDHMIQSL 237
Cdd:PRK07681 240 SYSLAGSRIGYMIGNEEIVRALTQFKSNtdyGVF-LPIQKAACAAL---RNGAAFCEKNRGIYQ------ERRDTLVDGF 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 238 QSVGLKPLIPQGSYFLIADISDFKSSMpdlpgamdepydtRFAKWMIKNKGLSAIPVSTFysQPHHkdfDHYIRFCFVKD 317
Cdd:PRK07681 310 RTFGWNVDKPAGSMFVWAEIPKGWTSL-------------SFAYALMDRANVVVTPGHAF--GPHG---EGFVRIALVQD 371
|
330
....*....|.
gi 1720400629 318 KATLQAMDKRL 328
Cdd:PRK07681 372 EEVLQQAVENI 382
|
|
| C_S_lyase_PatB |
TIGR04350 |
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of ... |
5-267 |
1.63e-28 |
|
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of pyridoxal phosphate-dependent enzymes that tend to be (mis)annotated as probable aminotransferases. One member is PatB of Bacillus subtilis, a proven C-S-lyase. Another is the virulence factor cystalysin from Treponema denticola, whose hemolysin activity may stem from H2S production. Members of the seed alignment occur next to examples of the enzyme 5-histidylcysteine sulfoxide synthase, from ovothiol A biosynthesis, and would be expected to perform a C-S cleavage of 5-histidylcysteine sulfoxide to leave 1-methyl-4-mercaptohistidine (ovothiol A).
Pssm-ID: 275146 Cd Length: 384 Bit Score: 113.57 E-value: 1.63e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 5 KNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAfncYEPMTMMAG--GRP-VFVSLRLSPapkgqlgssNDWQLDPTELA 81
Cdd:TIGR04350 84 EDIVFLPGVVPSLFAAVRALTAPGEGVIVQTPV---YPPFLSAVKsnGRElVLNPLKLDE---------GRYRFDLEDLE 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASL-PGMWERTLTIGSAGK 160
Cdd:TIGR04350 152 DAITEKARLLLLCSPHNPVGRVWTREELTRLAELCLRHNVVVVSDEIHADLVYPPNKHIPLASLsPEPAERTVTLLSPGK 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 161 SFSATGWKVGWVMGPDNIMKH-LRTVHQNSifHCP-------TQAQAAVaqcfereqqHFGQPssYFLQLPQAMGLNRDH 232
Cdd:TIGR04350 232 TFNIAGLNISFAIIPNPELRRaFQEAAQRV--HIQhgnlfgyVAFEAAY---------RDGEP--WLDALLAYLRGNRDL 298
|
250 260 270
....*....|....*....|....*....|....*..
gi 1720400629 233 MIQSLQSV--GLKPLIPQGSYFLIADISDFKSSMPDL 267
Cdd:TIGR04350 299 VEEFIAKRlpQIRVRPPEATYLAWLDCRALGLDDADL 335
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
22-173 |
5.37e-27 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 110.98 E-value: 5.37e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 22 QALVDEGDEVIIIEPAFNCYEPMTMMAGGRPV-FVSLRlspapkgqlgsSNDWQLDPTELASKFTPRTKILVLNTPNNPL 100
Cdd:PRK13355 226 SALLDDGDEVLIPSPDYPLWTACVNLAGGTAVhYRCDE-----------QSEWYPDIDDIRSKITSRTKAIVIINPNNPT 294
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720400629 101 GKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASL-PGMWerTLTIGSAGKSFSATGWKVGWVM 173
Cdd:PRK13355 295 GALYPREVLQQIVDIAREHQLIIFSDEIYDRLVMDGLEHTSIASLaPDLF--CVTFSGLSKSHMIAGYRIGWMI 366
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
1-328 |
2.62e-26 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 107.82 E-value: 2.62e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRpvfvslrLSPAPkgqLGSSNDWQLDPTEL 80
Cdd:PRK06290 103 IDPVTEVIHSIGSKPALAMLPSCFINPGDVTLMTVPGYPVTGTHTKYYGGE-------VYNLP---LLEENNFLPDLDSI 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 81 ASKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQhISIASLPGMWERTLTIGSAGK 160
Cdd:PRK06290 173 PKDIKEKAKLLYLNYPNNPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALTFDGKP-LSFLSVPGAKEVGVEIHSLSK 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 161 SFSATGWKVGWVMGPDNIMKHLRTVHQNS-----IfhcPTQAQAAvaqcfereqqhfgqpssYFLQLPQAMGLNR----- 230
Cdd:PRK06290 252 AYNMTGWRLAFVVGNELIVKAFATVKDNNdsgqfI---AIQKAGI-----------------YALDHPEITEKIRekysr 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 231 --DHMIQSLQSVGLKPLIPQGSYFLIADISDFKSSMPDLPGAMDepydtrFAKWMIKNKGLSAIPvstfysqphHKDFDH 308
Cdd:PRK06290 312 rlDKLVKILNEVGFKAEMPGGTFYLYVKAPKGTKSGIKFENAEE------FSQYLIKEKLISTVP---------WDDAGH 376
|
330 340
....*....|....*....|....*..
gi 1720400629 309 YIRF--CFV-----KDKATLQAMDKRL 328
Cdd:PRK06290 377 FLRFsvTFEakdeeEEDRILEEIKRRL 403
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
5-297 |
8.55e-26 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 106.27 E-value: 8.55e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 5 KNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEpmtmmagGRPVFVSLRLSPApkgQLGSSNDWQLDPTELASKF 84
Cdd:TIGR01265 97 DDVVLTSGCSQAIEICIEALANPGANILVPRPGFPLYD-------TRAAFSGLEVRLY---DLLPEKDWEIDLDGLESLA 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 85 TPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERtLTIGSAGKSFSA 164
Cdd:TIGR01265 167 DEKTVAIVVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAPFIPMASFASIVPV-LSLGGISKRWVV 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 165 TGWKVGWVM--GPDNIMKH-----LRTVHQNSIFHCpTQAQAAVAQCFEReqqhfgQPSSYFLQLPQAMGLNRDHMIQSL 237
Cdd:TIGR01265 246 PGWRLGWIIihDPHGIFRDtvlqgLKNLLQRILGPA-TIVQGALPDILEN------TPQEFFDGKISVLKSNAELCYEEL 318
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720400629 238 QSV-GLKPLIPQGSYFLIADISdfKSSMPDLPGamdepyDTRFAKWMIKNKGLSAIPVSTF 297
Cdd:TIGR01265 319 KDIpGLVCPKPEGAMYLMVKLE--LELFPEIKD------DVDFCEKLAREESVICLPGSAF 371
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
1-326 |
1.28e-24 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 102.92 E-value: 1.28e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRLSPAPKGQlgssndwQLDPTEL 80
Cdd:PRK06207 99 VDAADELIITPGTQGALFLAVAATVARGDKVAIVQPDYFANRKLVEFFEGEMVPVQLDYLSADKRA-------GLDLDQL 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 81 ASKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGK 160
Cdd:PRK06207 172 EEAFKAGVRVFLFSNPNNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLLYDGTSYTHLRALPIDPENVITIMGPSK 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 161 SFSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVaqcfereQQHFGQPSSYF---LQLPQAMglnRDHMIQSL 237
Cdd:PRK06207 252 TESLSGYRLGVAFGSPAIIDRMEKLQAIVSLRAAGYSQAVL-------RTWFSEPDGWMkdrIARHQAI---RDDLLRVL 321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 238 QSV-GLKPLIPQ-GSYFLiadisdfkssmPDLPGAMDEPYDtrFAKWMIKNKGLSAIPVSTFysQPHhkdFDHYIRFCFV 315
Cdd:PRK06207 322 RGVeGVFVRAPQaGSYLF-----------PRLPRLAVSLHD--FVKILRLQAGVIVTPGTEF--SPH---TADSIRLNFS 383
|
330
....*....|..
gi 1720400629 316 KD-KATLQAMDK 326
Cdd:PRK06207 384 QDhAAAVAAAER 395
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
6-183 |
3.01e-24 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 101.55 E-value: 3.01e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFN-CYE-PMTMMAGgrpvfVSLRlspapkgQLGSSNDWQLDPTELASK 83
Cdd:PRK07324 82 NILQTNGATGANFLVLYALVEPGDHVISVYPTYQqLYDiPESLGAE-----VDYW-------QLKEENGWLPDLDELRRL 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 84 FTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGhqhiSIASLPGMWERTLTIGSAGKSFS 163
Cdd:PRK07324 150 VRPNTKLICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVYRPLDEDG----STPSIADLYEKGISTNSMSKTYS 225
|
170 180
....*....|....*....|
gi 1720400629 164 ATGWKVGWVMGPDNIMKHLR 183
Cdd:PRK07324 226 LPGIRVGWIAANEEVIDILR 245
|
|
| PRK09276 |
PRK09276 |
LL-diaminopimelate aminotransferase; Provisional |
1-255 |
1.49e-23 |
|
LL-diaminopimelate aminotransferase; Provisional
Pssm-ID: 181749 Cd Length: 385 Bit Score: 99.99 E-value: 1.49e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspAPKGQLgssNDWQLDPTEL 80
Cdd:PRK09276 90 LDPETEVISLIGSKEGIAHIPLAFVNPGDVVLVPDPGYPVYKIGTIFAGGEPYFMPLK---EENGFL---PDLDAIPEDV 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 81 ASKftprTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGK 160
Cdd:PRK09276 164 AKK----AKLMFINYPNNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSEIAYDGYKPPSFLEVPGAKDVGIEFHSLSK 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 161 SFSATGWKVGWVMGPDNIMKHLRTVHQN---SIFhcptQA-QAAVAQCFEREQQHFGQPSSYFLQlpqamglNRDHMIQS 236
Cdd:PRK09276 240 TYNMTGWRIGFAVGNADLIAGLGKVKSNvdsGVF----QAiQEAGIAALNGPQEVVEELRKIYQE-------RRDILVEG 308
|
250
....*....|....*....
gi 1720400629 237 LQSVGLKPLIPQGSYFLIA 255
Cdd:PRK09276 309 LRKLGLEVEPPKATFYVWA 327
|
|
| PRK05942 |
PRK05942 |
aspartate aminotransferase; Provisional |
1-253 |
7.21e-21 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 180317 Cd Length: 394 Bit Score: 92.47 E-value: 7.21e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRpvFVSLRLSPapkgqlgsSNDWQLDPTEL 80
Cdd:PRK05942 94 LDPDSEALPLLGSKEGLTHLALAYVNPGDVVLVPSPAYPAHFRGPLIAGAQ--IYPIILKP--------ENDWLIDLSSI 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 81 ASKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGK 160
Cdd:PRK05942 164 PEEVAQQAKILYFNYPSNPTTATAPREFFEEIVAFARKYEIMLVHDLCYAELAFDGYQPTSLLEIPGAKDIGVEFHTLSK 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 161 SFSATGWKVGWVMGPDNIMKHLRTVHQN---SIFHCpTQAQAAVAqcfereqqhFGQPSSYFLQLPQAMGLNRDHMIQSL 237
Cdd:PRK05942 244 TYNMAGWRVGFVVGNRHIIQGLRTLKTNldyGIFSA-LQKAAETA---------LQLPDSYLQQVQERYRTRRDFLIQGL 313
|
250
....*....|....*.
gi 1720400629 238 QSVGLKPLIPQGSYFL 253
Cdd:PRK05942 314 GELGWNIPPTKATMYL 329
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
6-202 |
1.38e-18 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 85.78 E-value: 1.38e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPA-FNcyEPMTM-MAGGRPVFVslrlsPAPKGqlgssNDWQLDPTELASK 83
Cdd:PRK07550 92 QVHITSGCNQAFWAAMVTLAGAGDEVILPLPWyFN--HKMWLdMLGIRPVYL-----PCDEG-----PGLLPDPAAAEAL 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 84 FTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGmWERTLT-IGSAGKSF 162
Cdd:PRK07550 160 ITPRTRAIALVTPNNPTGVVYPPELLHELYDLARRHGIALILDETYRDFDSGGGAPHDLFADPD-WDDTLVhLYSFSKSY 238
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1720400629 163 SATGWKVGWVM-GPD---NIMKHLRTVhqnSIfhCPTQ-AQAAVA 202
Cdd:PRK07550 239 ALTGHRVGAVVaSPAriaEIEKFMDTV---AI--CAPRiGQIAVA 278
|
|
| PRK08175 |
PRK08175 |
aminotransferase; Validated |
1-324 |
1.24e-16 |
|
aminotransferase; Validated
Pssm-ID: 181268 [Multi-domain] Cd Length: 395 Bit Score: 80.14 E-value: 1.24e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLrlspAPKGQLgssndwqLDPTEL 80
Cdd:PRK08175 88 IDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPL----VEGVDF-------FNELER 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 81 ASKFT-PRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAG 159
Cdd:PRK08175 157 AIRESyPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDVAVEFFTLS 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 160 KSFSATGWKVGWVMG-PDNI--MKHLRTVHQNSIFhCPTQAQAAVA-----QCFEREQQHFGQpssyflqlpqamglNRD 231
Cdd:PRK08175 237 KSYNMAGWRIGFMVGnPELVsaLARIKSYHDYGTF-TPLQVAAIAAlegdqQCVRDIAEQYKR--------------RRD 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 232 HMIQSLQSVGLKPLIPQGSYFLIADISDFKSSMPDLpgamdepydtRFAKWMIKNKGLSAIPVSTFYSQPhhkdfDHYIR 311
Cdd:PRK08175 302 VLVKGLHEAGWMVEMPKASMYVWAKIPEPYAAMGSL----------EFAKKLLNEAKVCVSPGIGFGDYG-----DTHVR 366
|
330
....*....|....
gi 1720400629 312 FCFVKDKA-TLQAM 324
Cdd:PRK08175 367 FALIENRDrIRQAI 380
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
1-293 |
7.89e-16 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 77.80 E-value: 7.89e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGrpvfvSLRLSPApkgqlgSSNDWQLDPTEL 80
Cdd:PRK09148 89 LNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPSYPIHAFGFIMAGG-----VIRSVPA------EPDEEFFPALER 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 81 ASKFT-PRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAG 159
Cdd:PRK09148 158 AVRHSiPKPIALIVNYPSNPTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYFDGNPPPSVLQVPGAKDVTVEFTSMS 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 160 KSFSATGWKVGWVMGPDNIMKHLRTVHQNSIF--HCPTQAQAAVAqcfereqqhFGQPSSYFLQLPQAMGLNRDHMIQSL 237
Cdd:PRK09148 238 KTFSMAGWRMGFAVGNERLIAALTRVKSYLDYgaFTPIQVAATAA---------LNGPQDCIAEMRELYKKRRDVLVESF 308
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1720400629 238 QSVGLKPLIPQGSYFLIADISDFKSSMpdlpGAMDepydtrFAKWMIKNKGLSAIP 293
Cdd:PRK09148 309 GRAGWDIPPPAASMFAWAPIPEAFRHL----GSLE------FSKLLVEKADVAVAP 354
|
|
| PRK08068 |
PRK08068 |
transaminase; Reviewed |
2-252 |
2.58e-13 |
|
transaminase; Reviewed
Pssm-ID: 181219 Cd Length: 389 Bit Score: 69.95 E-value: 2.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgSSNDWQLDPTELA 81
Cdd:PRK08068 92 DPETEVAILFGGKAGLVELPQCLMNPGDTILVPDPGYPDYLSGVALARAQFETMPLI----------AENNFLPDYTKIP 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 82 SKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKS 161
Cdd:PRK08068 162 EEVAEKAKLMYLNYPNNPTGAVATKAFFEETVAFAKKHNIGVVHDFAYGAIGFDGQKPVSFLQTPGAKDVGIELYTLSKT 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 162 FSATGWKVGWVMGPDNIMKHLRTVHQN---SIFhcP-TQAQAAVAqcfereqqhfgqpssyfLQLPQA--MGLN------ 229
Cdd:PRK08068 242 FNMAGWRVAFAVGNESVIEAINLLQDHlfvSLF--GaIQDAAIEA-----------------LLSDQScvAELVaryesr 302
|
250 260
....*....|....*....|...
gi 1720400629 230 RDHMIQSLQSVGLKPLIPQGSYF 252
Cdd:PRK08068 303 RNAFISACREIGWEVDAPKGSFF 325
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
7-183 |
2.75e-13 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 69.78 E-value: 2.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 7 VLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLrLSPApkgqlgssNDWQLDPTELASKFTP 86
Cdd:PRK06225 86 ALITAGATESLYLVMRAFLSPGDNAVTPDPGYLIIDNFASRFGAEVIEVPI-YSEE--------CNYKLTPELVKENMDE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 87 RTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVyDGHqHISIASLPgmwERTLTIGSAGKSFSATG 166
Cdd:PRK06225 157 NTRLIYLIDPLNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYRDFA-REH-TLAAEYAP---EHTVTSYSFSKIFGMAG 231
|
170
....*....|....*..
gi 1720400629 167 WKVGWVMGPDNIMKHLR 183
Cdd:PRK06225 232 LRIGAVVATPDLIEVVK 248
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
6-137 |
9.60e-13 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 68.84 E-value: 9.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALV-DEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgSSNDWQLDPTELA--- 81
Cdd:PTZ00377 140 DIFLTDGASSGIKLLLQLLIgDPSDGVMIPIPQYPLYSAAITLLGGKQVPYYLD----------EEKGWSLDQEELEeay 209
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720400629 82 -----SKFTPRtkILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGH 137
Cdd:PTZ00377 210 eqavrNGITPR--ALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYQENIYDGE 268
|
|
| PRK08636 |
PRK08636 |
LL-diaminopimelate aminotransferase; |
1-267 |
9.70e-13 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 236316 Cd Length: 403 Bit Score: 68.58 E-value: 9.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRpvfVSlrlspapKGQLGSSNDWQLDPTEL 80
Cdd:PRK08636 92 LDPETEVVATMGSKEGYVHLVQAITNPGDVAIVPDPAYPIHSQAFILAGGN---VH-------KMPLEYNEDFELDEDQF 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 81 ASKF-------TPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTL 153
Cdd:PRK08636 162 FENLekalresSPKPKYVVVNFPHNPTTATVEKSFYERLVALAKKERFYIISDIAYADITFDGYKTPSILEVEGAKDVAV 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 154 TIGSAGKSFSATGWKVGWVMGPDNIMKHLRTVhqNSIF----HCPTQAQAAVA-----QCFEREQQHFGQpssyflqlpq 224
Cdd:PRK08636 242 ESYTLSKSYNMAGWRVGFVVGNKKLVGALKKI--KSWLdygmFTPIQVAATIAldgdqSCVEEIRETYRK---------- 309
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1720400629 225 amglNRDHMIQSLQSVGLKPLIPQGSYFLIADISDFKSSMPDL 267
Cdd:PRK08636 310 ----RRDVLIESFANAGWELQKPRASMFVWAKIPEPARHLGSL 348
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
6-259 |
3.78e-12 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 66.57 E-value: 3.78e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTmmaggrpVFVSLRLSpapKGQLGSSNDWQLDPTELASKFT 85
Cdd:PLN00143 99 DVYLTLGCKHAAEIIIKVLARPEANILLPRPGFPDVETYA-------IFHHLEIR---HFDLLPEKGWEVDLDAVEAIAD 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 86 PRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYdGHQHISIASLPGMWERTLTIGSAGKSFSAT 165
Cdd:PLN00143 169 ENTIAMVIINPGNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVF-GSKPFVPMGLFASIVPVITLGSISKRWMIP 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 166 GWKVGWVMGPD--------NIMKHLRTVHQNSIFHcPTQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMGLNRDHMIQSL 237
Cdd:PLN00143 248 GWGLGWLVTCDpsgllqicEIADSIKKALNPAPFP-PTFIQAAIPEILEKTTEDFFSKTINILRAALAFCYDKLKEIPCI 326
|
250 260 270
....*....|....*....|....*....|
gi 1720400629 238 qsvgLKPLIPQGSYF--------LIADISD 259
Cdd:PLN00143 327 ----MCPQKAEGAFFalvklnllLLEDIED 352
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
5-212 |
5.84e-12 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 66.29 E-value: 5.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 5 KNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGgrpvfVSLRlspapKGQLGSSNDWQLDPTELASKF 84
Cdd:PLN02187 132 EDIFLTAGCNQGIEIVFESLARPNANILLPRPGFPHYDARAAYSG-----LEVR-----KFDLLPEKEWEIDLEGIEAIA 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 85 TPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWErTLTIGSAGKSFSA 164
Cdd:PLN02187 202 DENTVAMVVINPNNPCGNVYSHDHLKKVAETARKLGIMVISDEVYDRTIFGDNPFVSMGKFASIVP-VLTLAGISKGWVV 280
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1720400629 165 TGWKVGWVM--GPDNIM---KHLRTVHQN-SIFHCP-TQAQAAVAQCFEREQQHF 212
Cdd:PLN02187 281 PGWKIGWIAlnDPEGVFettKVLQSIKQNlDVTPDPaTIIQAALPAILEKADKNF 335
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
4-259 |
1.59e-11 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 64.95 E-value: 1.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 4 LKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEpmtMMAGGRPVFVS-LRLSPapkgqlgsSNDWQLDPTELAS 82
Cdd:PLN02656 96 LDDVFITSGCTQAIDVALSMLARPGANILLPRPGFPIYE---LCAAFRHLEVRyVDLLP--------EKGWEVDLDAVEA 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 83 KFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLpGMWERTLTIGSAGKSF 162
Cdd:PLN02656 165 LADQNTVALVIINPGNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFGSNPFVPMGVF-GSIVPVLTLGSLSKRW 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 163 SATGWKVGW--VMGPDNIMKHLRTVHQ----NSIFHCP-TQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMGLNRDHMIQ 235
Cdd:PLN02656 244 IVPGWRLGWfvTTDPSGSFRDPKIVERikkyFDILGGPaTFIQAAVPTILEQTDESFFKKTINILKQSSDICCDRIKEIP 323
|
250 260 270
....*....|....*....|....*....|..
gi 1720400629 236 SLQSvglkPLIPQGSYF--------LIADISD 259
Cdd:PLN02656 324 CITC----PHKPEGSMAvmvklnlsLLEDISD 351
|
|
| PRK09147 |
PRK09147 |
succinyldiaminopimelate transaminase; Provisional |
1-137 |
1.59e-10 |
|
succinyldiaminopimelate transaminase; Provisional
Pssm-ID: 236393 Cd Length: 396 Bit Score: 61.81 E-value: 1.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 1 MDPLKNVLVTVGAYGALFTAFQALVDEGDE---VIIIEPAFNCYEPMTMMAGGRPVFVSlrlSPAPKGQLGssnDW-QLD 76
Cdd:PRK09147 87 LDPATQVLPVNGSREALFAFAQTVIDRDGPgplVVCPNPFYQIYEGAALLAGAEPYFLN---CDPANNFAP---DFdAVP 160
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720400629 77 PTELAskftpRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGH 137
Cdd:PRK09147 161 AEVWA-----RTQLLFVCSPGNPTGAVLPLDDWKKLFALSDRYGFVIASDECYSEIYFDEA 216
|
|
| PRK07366 |
PRK07366 |
LL-diaminopimelate aminotransferase; |
23-328 |
2.33e-10 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 180947 Cd Length: 388 Bit Score: 61.23 E-value: 2.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 23 ALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRlspapkgqlgSSNDWQLDPTELASKFTPRTKILVLNTPNNPLGK 102
Cdd:PRK07366 111 AVLNPGDFALLLDPGYPSHAGGVYLAGGQIYPMPLR----------AENDFLPVFADIPTEVLAQARLMVLSYPHNPTTA 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 103 VFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHI-SIasLPGMWERTLTIG--SAGKSFSATGWKVGWVMGPDNIM 179
Cdd:PRK07366 181 IAPLSFFQEAVAFCQQHDLVLVHDFPYVDLVFDGEVEPpSI--LQADPEKSVSIEffTLSKSYNMGGFRIGFAIGNAQLI 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 180 KHLRTV------HQ-----NSIFHCPTQAQAAVAQCFEREQQHfgqpssyflqlpqamglnRDHMIQSLQSVGLKPLIPQ 248
Cdd:PRK07366 259 QALRQVkavvdfNQyrgilNGAIAALTGPQATVQQTVQIFRQR------------------RDAFINALHQIGWPVPLPE 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 249 GSYFLIAdisdfkssmpDLPgamdEPYDTR---FAKWMIKNKGLSAIPVSTFysqphHKDFDHYIRFCFVKDKATLQAMD 325
Cdd:PRK07366 321 ATMYVWA----------KLP----EPWQGNsveFCTQLVAQTGVAASPGSGF-----GKSGEGYVRFALVHDPDILEEAV 381
|
...
gi 1720400629 326 KRL 328
Cdd:PRK07366 382 ERI 384
|
|
| PRK06855 |
PRK06855 |
pyridoxal phosphate-dependent aminotransferase; |
48-148 |
2.78e-10 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180734 Cd Length: 433 Bit Score: 61.12 E-value: 2.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 48 AGGRPVfvSLRLSPApkgqlgssNDWQLDPTELAS--KFTPR-TKILVLNtPNNPLGKVFSKKELELVAALCQQHDVLCF 124
Cdd:PRK06855 140 AGYPPV--TYRLDPE--------NNWYPDLDDLENkvKYNPSiAGILLIN-PDNPTGAVYPKEILREIVDIAREYDLFII 208
|
90 100
....*....|....*....|....*...
gi 1720400629 125 SDEVYQWLVYDGHQHISIASL----PGM 148
Cdd:PRK06855 209 CDEIYNNIVYNGKKTVPLSEVigdvPGI 236
|
|
| PRK03321 |
PRK03321 |
putative aminotransferase; Provisional |
3-210 |
2.79e-10 |
|
putative aminotransferase; Provisional
Pssm-ID: 179559 Cd Length: 352 Bit Score: 60.75 E-value: 2.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 3 PLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRLspapkgqlGSSNDwqLDptELAS 82
Cdd:PRK03321 73 PPEHVAVGCGSVALCQQLVQATAGPGDEVIFAWRSFEAYPILVQVAGATPVQVPLTP--------DHTHD--LD--AMAA 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 83 KFTPRTKILVLNTPNNPLGKVFSKKELE-LVAALcqQHDVLCFSDEVYQWLVYDG---------HQHISIASLpgmweRT 152
Cdd:PRK03321 141 AITDRTRLIFVCNPNNPTGTVVTPAELArFLDAV--PADVLVVLDEAYVEYVRDDdvpdglelvRDHPNVVVL-----RT 213
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1720400629 153 LTigsagKSFSATGWKVGWVMGPDNIMKHLRTVHQNsiFHCPTQAQAAVAQCFEREQQ 210
Cdd:PRK03321 214 FS-----KAYGLAGLRVGYAVGHPEVIAALRKVAVP--FSVNSLAQAAAIASLAAEDE 264
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
6-212 |
1.51e-08 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 55.55 E-value: 1.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRpvFVSLRLSPapkgqlgsSNDWQLDPTELASKFT 85
Cdd:PLN00145 119 DIYLTAGCAQAIEIIMSVLAQPGANILLPRPGYPLYEARAVFSGLE--VRHFDLLP--------ERGWEVDLEGVEALAD 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 86 PRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLpGMWERTLTIGSAGKSFSAT 165
Cdd:PLN00145 189 ENTVAMVIINPNNPCGSVYSYEHLAKIAETARKLGILVIADEVYDHLTFGSKPFVPMGVF-GEVAPVLTLGSISKRWVVP 267
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1720400629 166 GWKVGWVM--GPDNIMKHLRTVHQNSIFHC-----PTQAQAAVAQCFEREQQHF 212
Cdd:PLN00145 268 GWRLGWIAtcDPNGILKETKVVDSIRNYLNistdpATFVQGAIPQIIANTKEEF 321
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
5-163 |
3.28e-08 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 54.47 E-value: 3.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 5 KNVLVTVGAYGALFTAFQAL-VDEGDEVIIiePAF------NCyepmTMMAGGRPVFVSLRLspapkgqlgssNDWQLDP 77
Cdd:cd00616 34 KYAVAVSSGTAALHLALRALgIGPGDEVIV--PSFtfvataNA----ILLLGATPVFVDIDP-----------DTYNIDP 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 78 TELASKFTPRTK-ILVLNTpnnpLGKVFskkELELVAALCQQHDVlcfsdevyqWLVYDGHQhisiaSLPGMWE--RTLT 154
Cdd:cd00616 97 ELIEAAITPRTKaIIPVHL----YGNPA---DMDAIMAIAKRHGL---------PVIEDAAQ-----ALGATYKgrKVGT 155
|
....*....
gi 1720400629 155 IGSAGkSFS 163
Cdd:cd00616 156 FGDAG-AFS 163
|
|
| PRK05839 |
PRK05839 |
succinyldiaminopimelate transaminase; |
67-328 |
5.76e-08 |
|
succinyldiaminopimelate transaminase;
Pssm-ID: 180281 Cd Length: 374 Bit Score: 53.92 E-value: 5.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 67 LGSSNDWQ--LDPTELAskftpRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQwlvyDGHQHISIAS 144
Cdd:PRK05839 138 LTKENDFTpsLNEKELQ-----EVDLVILNSPNNPTGRTLSLEELIEWVKLALKHDFILINDECYS----EIYENTPPPS 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 145 L--------PGMWERTLTIGSAGKSFSATGWKVGWVMGPDNIMKHLRTVHqnSIFHC----PTQAQAAVAQCFEREQQHF 212
Cdd:PRK05839 209 LleasilvgNESFKNVLVINSISKRSSAPGLRSGFIAGDASILKKYKAYR--TYLGCasplPLQKAAAVAWLDDEHAEFF 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 213 GQPSSYFLQLPQAMglnrdhmiqslqsvgLKPLIPQGSYFLIADISDfkssmpdlpgamdepyDTRFAKWMIKNKGLSAI 292
Cdd:PRK05839 287 RNIYAKNLKLAREI---------------LGITIPPATFYVWLPVDN----------------DEEFTKKLYQNEGIKVL 335
|
250 260 270
....*....|....*....|....*....|....*.
gi 1720400629 293 PVSTFYSQPHHKDfdhYIRFCFVKDKATLQAMDKRL 328
Cdd:PRK05839 336 PGSFLGRNGIGKG---YVRIALVYDTPKLEKALEII 368
|
|
| PLN02607 |
PLN02607 |
1-aminocyclopropane-1-carboxylate synthase |
69-258 |
3.77e-07 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 215327 [Multi-domain] Cd Length: 447 Bit Score: 51.43 E-value: 3.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 69 SSNDWQLDPTELASKFTP------RTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISI 142
Cdd:PLN02607 176 SSNNFQVTPQALEAAYQEaeaaniRVRGVLITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSGSVFSASEFVSV 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 143 ASL------PGMWERTLTIGSAGKSFSATGWKVGWVMGPDNimKHLRTVHQNSIFH-CPTQAQAAVAQCFEREQqhFGQp 215
Cdd:PLN02607 256 AEIveargyKGVAERVHIVYSLSKDLGLPGFRVGTIYSYND--KVVTTARRMSSFTlVSSQTQHLLASMLSDEE--FTE- 330
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1720400629 216 sSYFLQLPQAMGLNRDHMIQSLQSVGLKPLIPQGSYFLIADIS 258
Cdd:PLN02607 331 -NYIRTNRERLRKRYEMIVQGLRRAGIECLKGNAGLFCWMNLS 372
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
16-135 |
1.52e-06 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 49.30 E-value: 1.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 16 ALFTAFQAL-VDEGDEVIIiePAF------NCYepmtMMAGGRPVFVSLRLspapkgqlgssNDWQLDPTELASKFTPRT 88
Cdd:COG0399 57 ALHLALRALgIGPGDEVIT--PAFtfvataNAI----LYVGATPVFVDIDP-----------DTYNIDPEALEAAITPRT 119
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1720400629 89 K--ILVlntpnNPLGKVFskkELELVAALCQQHDVlcfsdevyqWLVYD 135
Cdd:COG0399 120 KaiIPV-----HLYGQPA---DMDAIMAIAKKHGL---------KVIED 151
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
5-126 |
1.96e-06 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 48.82 E-value: 1.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 5 KNVLVTVGAYGALFTAFQAL-VDEGDEVIIiePAFncyepmTMMA--------GGRPVFVSlrlsPAPkgqlgssNDWQL 75
Cdd:pfam01041 40 KHAIAVSSGTAALHLALRALgVGPGDEVIT--PSF------TFVAtanaalrlGAKPVFVD----IDP-------DTYNI 100
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1720400629 76 DPTELASKFTPRTKILVlntPNNPLGKVFskkELELVAALCQQHDVLCFSD 126
Cdd:pfam01041 101 DPEAIEAAITPRTKAII---PVHLYGQPA---DMDAIRAIAARHGLPVIED 145
|
|
| PLN02368 |
PLN02368 |
alanine transaminase |
2-134 |
4.96e-06 |
|
alanine transaminase
Pssm-ID: 177996 [Multi-domain] Cd Length: 407 Bit Score: 47.87 E-value: 4.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPlKNVLVTVGAYGALFTAFQALV-DEGDEVIIIEPAFNCYEPMTMMAGGR--PVFvslrlspapkgqLGSSNDWQLDPT 78
Cdd:PLN02368 129 DP-ELIFLTDGASKGVMQILNAVIrGEKDGVLVPVPQYPLYSATISLLGGTlvPYY------------LEESENWGLDVN 195
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720400629 79 EL--------ASKFTPRTkiLVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVY 134
Cdd:PLN02368 196 NLrqsvaqarSKGITVRA--MVIINPGNPTGQCLSEANLREILKFCYQERLVLLGDEVYQQNIY 257
|
|
| PLN02376 |
PLN02376 |
1-aminocyclopropane-1-carboxylate synthase |
2-145 |
6.35e-06 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178004 [Multi-domain] Cd Length: 496 Bit Score: 47.77 E-value: 6.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 2 DPlKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGrpvfvsLRLSPAPkgqLGSSNDWQL--DPTE 79
Cdd:PLN02376 118 DP-ERVVMSGGATGANETIMFCLADPGDVFLIPSPYYAAFDRDLRWRTG------VEIIPVP---CSSSDNFKLtvDAAD 187
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 80 LASK----FTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASL 145
Cdd:PLN02376 188 WAYKkaqeSNKKVKGLILTNPSNPLGTMLDKDTLTNLVRFVTRKNIHLVVDEIYAATVFAGGDFVSVAEV 257
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
7-130 |
1.01e-05 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 45.07 E-value: 1.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 7 VLVTVGAYGALFTAFQALVDEGDEVIIIEPAF-NCYEPMTMMAGGRPVFVslrlsPAPKGQLGSSNDWQLDPTELAskft 85
Cdd:cd01494 20 AVFVPSGTGANEAALLALLGPGDEVIVDANGHgSRYWVAAELAGAKPVPV-----PVDDAGYGGLDVAILEELKAK---- 90
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1720400629 86 PRTKILVLNTPNNPLGKVFSKKElelVAALCQQHDVLCFSDEVYQ 130
Cdd:cd01494 91 PNVALIVITPNTTSGGVLVPLKE---IRKIAKEYGILLLVDAASA 132
|
|
| PRK08354 |
PRK08354 |
putative aminotransferase; Provisional |
5-174 |
1.20e-05 |
|
putative aminotransferase; Provisional
Pssm-ID: 169399 Cd Length: 311 Bit Score: 46.26 E-value: 1.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 5 KNVLVTVGAYGALF-TAFQALvdEGDEVIIIEPAFNCYEPMTMMAGGRPVfvslrlspapKGQLgssndwqlDPTELAsK 83
Cdd:PRK08354 55 EPIVITAGITEALYlIGILAL--RDRKVIIPRHTYGEYERVARFFAARII----------KGPN--------DPEKLE-E 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 84 FTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQhISIASLPGMweRTLTigsagKSFS 163
Cdd:PRK08354 114 LVERNSVVFFCNPNNPDGKFYNFKELKPLLDAVEDRNALLILDEAFIDFVKKPES-PEGENIIKL--RTFT-----KSYG 185
|
170
....*....|.
gi 1720400629 164 ATGWKVGWVMG 174
Cdd:PRK08354 186 LPGIRVGYVKG 196
|
|
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
24-191 |
1.41e-05 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 46.78 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 24 LVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRLSPapkgqlgsSNDWQLDPTELASKFTPRTKILVLNTPNNPLGKV 103
Cdd:PRK09275 186 LLKAGDKIALMTPIFTPYLEIPELPRYDLEVVHINADE--------ENEWQYPDSELEKLRDPSIKALFLVNPSNPPSVA 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 104 FSKKELELVAALCQQH--DVLCFSDEVYQWLVyDGHQHIsIASLPgmwERTLTIGSAGKSFSATGWKVGWVMgpdnimkh 181
Cdd:PRK09275 258 MSDESLEKIADIVNEKrpDLMIITDDVYGTFV-DDFRSL-FAVLP---YNTILVYSFSKYFGATGWRLGVIA-------- 324
|
170
....*....|
gi 1720400629 182 lrtVHQNSIF 191
Cdd:PRK09275 325 ---LHEDNVF 331
|
|
| PLN02231 |
PLN02231 |
alanine transaminase |
6-134 |
2.68e-05 |
|
alanine transaminase
Pssm-ID: 177876 [Multi-domain] Cd Length: 534 Bit Score: 45.70 E-value: 2.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 6 NVLVTVGAYGALFTAFQALV-DEGDEVIIIEPAFNCYEPMTMMAGGRpvfvslrLSPApkgQLGSSNDWQLDPTELASKF 84
Cdd:PLN02231 193 DIFLTDGASPAVHMMMQLLIrSEKDGILCPIPQYPLYSASIALHGGT-------LVPY---YLDEATGWGLEISELKKQL 262
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1720400629 85 --------TPRTkiLVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVY 134
Cdd:PLN02231 263 edarskgiTVRA--LVVINPGNPTGQVLAEENQRDIVEFCKQEGLVLLADEVYQENVY 318
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
15-122 |
5.03e-05 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 44.50 E-value: 5.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 15 GALFTAFQALVDEGDEVIIIEpafNCYepmtmmaGGRPVFVSlRLSPApkgqLGSSNDW--QLDPTELASKFTPRTKILV 92
Cdd:cd00614 66 AAISTVLLALLKAGDHVVASD---DLY-------GGTYRLFE-RLLPK----LGIEVTFvdPDDPEALEAAIKPETKLVY 130
|
90 100 110
....*....|....*....|....*....|
gi 1720400629 93 LNTPNNPLGKVFskkELELVAALCQQHDVL 122
Cdd:cd00614 131 VESPTNPTLKVV---DIEAIAELAHEHGAL 157
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
15-126 |
5.13e-05 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 44.53 E-value: 5.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 15 GALFTAFQALVDEGDEVIIIEPAFncyepmtmmaGGRPVFVSLRLspaPKGQLGSSNDWQLDPTELASKFTPRTKILVLN 94
Cdd:pfam01053 73 AAITAAILALLKAGDHIVATDDLY----------GGTYRLFNKVL---PRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLE 139
|
90 100 110
....*....|....*....|....*....|..
gi 1720400629 95 TPNNPLGKVfskKELELVAALCQQHDVLCFSD 126
Cdd:pfam01053 140 TPTNPLLKV---VDIEAIAKLAKKHGILVVVD 168
|
|
| PLN02450 |
PLN02450 |
1-aminocyclopropane-1-carboxylate synthase |
66-170 |
7.67e-05 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178069 [Multi-domain] Cd Length: 468 Bit Score: 44.36 E-value: 7.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 66 QLGSSNDWQL------DPTELASKFTPRTK-ILVLNtPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQ 138
Cdd:PLN02450 164 HCSSSNGFQItesaleEAYQQAQKLNLKVKgVLITN-PSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFDSPG 242
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1720400629 139 HISIASL--------PGMWERTLTIGSAGKSFSATGWKVG 170
Cdd:PLN02450 243 FVSVMEVlkdrklenTDVSNRVHIVYSLSKDLGLPGFRVG 282
|
|
| Beta_elim_lyase |
pfam01212 |
Beta-eliminating lyase; |
12-121 |
8.92e-05 |
|
Beta-eliminating lyase;
Pssm-ID: 426128 [Multi-domain] Cd Length: 288 Bit Score: 43.36 E-value: 8.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 12 GAYGALFT---------AFQALVDEGDEVIIIEPAFNC-YEpmtmmAGGRPVFVSLRLSPAPkgqlgSSNDWQLDPTELA 81
Cdd:pfam01212 46 GKEAALFVpsgtaanqlALMAHCQRGDEVICGEPAHIHfDE-----TGGHAELGGVQPRPLD-----GDEAGNMDLEDLE 115
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1720400629 82 SKFT-------PRTKILVL-NTPNNPLGKVFSKKELELVAALCQQHDV 121
Cdd:pfam01212 116 AAIRevgadifPPTGLISLeNTHNSAGGQVVSLENLREIAALAREHGI 163
|
|
| PRK06425 |
PRK06425 |
histidinol-phosphate aminotransferase; Validated |
32-183 |
1.03e-03 |
|
histidinol-phosphate aminotransferase; Validated
Pssm-ID: 102370 Cd Length: 332 Bit Score: 40.61 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 32 IIIEPAFNCYEPMTMMAGgrpvfvsLRLSPAPKGQLGSsndwqlDPtELASKFTPRTKILVlnTPNNPLGKVFSKKELEL 111
Cdd:PRK06425 83 IIVEPNFNEYKGYAFTHG-------IRISALPFNLINN------NP-EILNNYNFDLIFIV--SPDNPLGNLISRDSLLT 146
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720400629 112 VAALCQQHDVLCFSDEVYQWLVYDGHQHI-SIASLPGmwerTLTIG-SAGKSFSATGWKVGWVMGPDNIMKHLR 183
Cdd:PRK06425 147 ISEICRKKGALLFIDEAFIDFVPNRAEEDvLLNRSYG----NVIIGrSLTKILGIPSLRIGYIATDDYNMKISR 216
|
|
| avtA |
PRK09440 |
valine--pyruvate transaminase; Provisional |
83-129 |
3.36e-03 |
|
valine--pyruvate transaminase; Provisional
Pssm-ID: 236517 Cd Length: 416 Bit Score: 39.07 E-value: 3.36e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1720400629 83 KFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVY 129
Cdd:PRK09440 175 HIDEDTGAICVSRPTNPTGNVLTDEELEKLDALARQHNIPLLIDNAY 221
|
|
| PRK08637 |
PRK08637 |
hypothetical protein; Provisional |
90-209 |
4.13e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 181512 Cd Length: 388 Bit Score: 38.78 E-value: 4.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720400629 90 ILVLNTPNNPLGKVFSKKEL-ELVAALCQQHD----VLCFSDEVYQWLVYDGHQHISI-ASLPGMWERTLTI--GSAGKS 161
Cdd:PRK08637 149 IVILNFPNNPTGYTPTEKEAtAIVEAIKELADagtkVVAVVDDAYFGLFYEDSYKESLfAALANLHSNILAVklDGATKE 228
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720400629 162 FSATGWKVGWV-----MGPDNIMKH---------LRTvhqnSIFHCPTQAQAAVAQCFEREQ 209
Cdd:PRK08637 229 EFVWGFRVGFItfgtkAGSSQTVKEalekkvkglIRS----NISNGPHPSQSAVLRALNSPE 286
|
|
| |
