endothelial differentiation-related factor 1 isoform X1 [Mus musculus]
Protein Classification
MBF1 domain-containing protein( domain architecture ID 10553810)
MBF1 domain-containing protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| MBF1 | pfam08523 | Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 ... |
5-71 | 5.87e-27 | ||
Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 (MBF1) which forms a heterodimer with MBF2. It has been shown to make direct contact with the TATA-box binding protein (TBP) and interacts with Ftz-F1, stabilising the Ftz-F1-DNA complex. It is also found in the endothelial differentiation-related factor (EDF-1). Human EDF-1 is involved in the repression of endothelial differentiation, interacts with CaM and is phosphorylated by PKC. The domain is found in a wide range of eukaryotic proteins including metazoans, fungi and plants. A helix-turn-helix motif (pfam01381) is found to its C-terminus. : Pssm-ID: 462508 Cd Length: 68 Bit Score: 95.77 E-value: 5.87e-27
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| Name | Accession | Description | Interval | E-value | ||
| MBF1 | pfam08523 | Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 ... |
5-71 | 5.87e-27 | ||
Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 (MBF1) which forms a heterodimer with MBF2. It has been shown to make direct contact with the TATA-box binding protein (TBP) and interacts with Ftz-F1, stabilising the Ftz-F1-DNA complex. It is also found in the endothelial differentiation-related factor (EDF-1). Human EDF-1 is involved in the repression of endothelial differentiation, interacts with CaM and is phosphorylated by PKC. The domain is found in a wide range of eukaryotic proteins including metazoans, fungi and plants. A helix-turn-helix motif (pfam01381) is found to its C-terminus. Pssm-ID: 462508 Cd Length: 68 Bit Score: 95.77 E-value: 5.87e-27
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| Name | Accession | Description | Interval | E-value | ||
| MBF1 | pfam08523 | Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 ... |
5-71 | 5.87e-27 | ||
Multiprotein bridging factor 1; This domain is found in the multiprotein bridging factor 1 (MBF1) which forms a heterodimer with MBF2. It has been shown to make direct contact with the TATA-box binding protein (TBP) and interacts with Ftz-F1, stabilising the Ftz-F1-DNA complex. It is also found in the endothelial differentiation-related factor (EDF-1). Human EDF-1 is involved in the repression of endothelial differentiation, interacts with CaM and is phosphorylated by PKC. The domain is found in a wide range of eukaryotic proteins including metazoans, fungi and plants. A helix-turn-helix motif (pfam01381) is found to its C-terminus. Pssm-ID: 462508 Cd Length: 68 Bit Score: 95.77 E-value: 5.87e-27
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