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Conserved domains on  [gi|1720397943|ref|XP_030104753|]
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excitatory amino acid transporter 2 isoform X1 [Mus musculus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10448728)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
37-486 2.06e-124

Sodium:dicarboxylate symporter family;


:

Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 370.70  E-value: 2.06e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943  37 LLSLTVFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 115
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 116 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 195
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 196 nttkavismlnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 275
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 276 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 355
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 356 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 435
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1720397943 436 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 486
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
37-486 2.06e-124

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 370.70  E-value: 2.06e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943  37 LLSLTVFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 115
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 116 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 195
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 196 nttkavismlnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 275
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 276 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 355
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 356 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 435
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1720397943 436 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 486
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
34-483 5.03e-124

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 370.21  E-value: 5.03e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943  34 KNLLLSLTVFGVILGAVCGGLLrlaspiHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 112
Cdd:COG1301     2 KLSLTLQILIALVLGILLGLLL------PELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 113 VYYMSTTIIAAVLGVILVLAIHPGNPkLKKQLGPGKKNDEVSSLDaFLDLIRNLFPENLVQAcfqqiqtvtkkvlvapps 192
Cdd:COG1301    76 LYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------ 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 193 eeanttkavismlnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 272
Cdd:COG1301   136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 273 MIMWYSPLGIACLIcGKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTA 352
Cdd:COG1301   182 WVMKLAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTS 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 353 SSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASI 432
Cdd:COG1301   260 SSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGV 339

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1720397943 433 PSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIV 483
Cdd:COG1301   340 PGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 34-493 1.01e-40

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 152.75  E-value: 1.01e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943  34 KNLLLSLTvFGVILGAVCGGLLRLaspIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 112
Cdd:PRK01663    3 KPLYKSLY-FQVLVAIIIGILLGH---FYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 113 VYYMSTTIIAAVLGVILVLAIHPGNpklkkqlgpgKKNDEVSSLDAfldlirnlfpenlvqacfQQIQTVTKKvlvappS 192
Cdd:PRK01663   79 LYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA------------------KAVAQYAAQ------A 124

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 193 EEANTTKAVISMLNETMNEApeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 272
Cdd:PRK01663  125 HEQGTVDFLMDIIPTTVVGA-------------FASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVN 190

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 273 MIMWYSPLG----IACLIcGKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAgiFQAWITA 348
Cdd:PRK01663  191 MIMKLAPIGafgaMAFTI-GKY-GVGSL----VQLGQLIGCFYITCIL----FVFVVLGAIARLTGFSIFK--FIRYIKE 258

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 349 -----LGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTAT 423
Cdd:PRK01663  259 ellivLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLL 337

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720397943 424 LASIGAASIPSAGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGDSFgAGIVYHLSKSELDT 493
Cdd:PRK01663  338 LTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKELDR 407
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
37-486 2.06e-124

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 370.70  E-value: 2.06e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943  37 LLSLTVFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYY 115
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 116 MSTTIIAAVLGVILVLAIHPGNPKLKKQLGPgkKNDEVSSLDAFLDLIRNLFPENLVQACFQQiqtvtkkvlvappseea 195
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASL--KEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 196 nttkavismlnetmneapeetkivikkglefkdgmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIM 275
Cdd:pfam00375 135 -----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVM 179

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 276 WYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSA 355
Cdd:pfam00375 180 KLAPIGVFALIA-NTVGTYGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSA 257

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 356 GTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSA 435
Cdd:pfam00375 258 ATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGG 337

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1720397943 436 GLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL 486
Cdd:pfam00375 338 GLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
34-483 5.03e-124

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 370.21  E-value: 5.03e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943  34 KNLLLSLTVFGVILGAVCGGLLrlaspiHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 112
Cdd:COG1301     2 KLSLTLQILIALVLGILLGLLL------PELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 113 VYYMSTTIIAAVLGVILVLAIHPGNPkLKKQLGPGKKNDEVSSLDaFLDLIRNLFPENLVQAcfqqiqtvtkkvlvapps 192
Cdd:COG1301    76 LYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------ 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 193 eeanttkavismlnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 272
Cdd:COG1301   136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 273 MIMWYSPLGIACLIcGKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTA 352
Cdd:COG1301   182 WVMKLAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTS 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 353 SSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASI 432
Cdd:COG1301   260 SSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGV 339

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1720397943 433 PSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIV 483
Cdd:COG1301   340 PGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 34-493 1.01e-40

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 152.75  E-value: 1.01e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943  34 KNLLLSLTvFGVILGAVCGGLLRLaspIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAM 112
Cdd:PRK01663    3 KPLYKSLY-FQVLVAIIIGILLGH---FYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 113 VYYMSTTIIAAVLGVILVLAIHPGNpklkkqlgpgKKNDEVSSLDAfldlirnlfpenlvqacfQQIQTVTKKvlvappS 192
Cdd:PRK01663   79 LYFEIVSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA------------------KAVAQYAAQ------A 124

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 193 EEANTTKAVISMLNETMNEApeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVI 272
Cdd:PRK01663  125 HEQGTVDFLMDIIPTTVVGA-------------FASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVN 190

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 273 MIMWYSPLG----IACLIcGKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAgiFQAWITA 348
Cdd:PRK01663  191 MIMKLAPIGafgaMAFTI-GKY-GVGSL----VQLGQLIGCFYITCIL----FVFVVLGAIARLTGFSIFK--FIRYIKE 258

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 349 -----LGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTAT 423
Cdd:PRK01663  259 ellivLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLL 337

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720397943 424 LASIGAASIPSAGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGDSFgAGIVYHLSKSELDT 493
Cdd:PRK01663  338 LTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKELDR 407
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 34-477 8.59e-40

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 150.30  E-value: 8.59e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943  34 KNLLLSLT---VFGVILGAVCGGLLRLASPIHPDVVMLIAFP-GDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLG 108
Cdd:PRK11283    2 KNIKFSLAwqiLIALVLGILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 109 TRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGP------GKKNDEVSSLD-AFLDLIRNLFPENLVQAcfqqiqt 181
Cdd:PRK11283   82 AKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATvdiskyQSTTEEVQSHShGLMGTILSLIPTNIFAS------- 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 182 vtkkvlvappseeanttkavismlnetmneapeetkivIKKGlefkdgmNVLGLIGFFIAFGIAMGKMGEQAKL-MVEFF 260
Cdd:PRK11283  155 --------------------------------------MAKG-------EMLPIIFFSVLFGLGLSSLPATHREpLVTVF 189

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 261 NILNEIVMKLVIMIMWYSPLGIACLIcgkiiaikdlEVVARQLGMYMITVIVGLII--HGGI--FLPLIYFVVTRKNPFS 336
Cdd:PRK11283  190 RSVSETMFKVTHMVMRYAPVGVFALI----------AVTVANFGFASLWPLAKLVLlvYFAIlfFALVVLGIVARLCGLS 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 337 FFAGIF---QAWITALGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGG 413
Cdd:PRK11283  260 IWILIRilkDELILAYSTASSETVLPRIIEKME-AYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIW 338

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720397943 414 QIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDS 477
Cdd:PRK11283  339 QEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNA 402
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 42-476 5.59e-36

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 139.42  E-value: 5.59e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943  42 VFGVILGAVCGGLLrlaspihPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRLGTRAMVYYMSTTI 120
Cdd:PRK13027   13 VIALVLGVALGAFF-------PHFAESLKPLGDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTT 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 121 IAAVLGVILVLAIHPG---NPKLKkQLGPGKKNDEVS---SLDAFLDLIRNLFPENLVQAcfqqiqtvtkkvlvappsee 194
Cdd:PRK13027   86 IALVIGLVLAYLTGPGvgmNIDLR-SLDAASLAGYAKnaqSLKGTAGFLLKLIPTTAVDA-------------------- 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 195 anttkavismlnetmneapeetkivikkgleFKDGmNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMI 274
Cdd:PRK13027  145 -------------------------------FAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFI 192

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 275 MWYSPLGIACLIC---GKIiAIKDLevvaRQLGMYMITVIVGLIIhggiFLPLIYFVVTRKNPFSFFAGIF---QAWITA 348
Cdd:PRK13027  193 IKLAPLGVLGAIAfttGKY-GVGSL----KQLGMLVAVFYLTCFV----FVVVVLGAVMRLAGFSVFKLIRylrEELLIV 263

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 349 LGTASSAGTLPVTFRCLEdNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIG 428
Cdd:PRK13027  264 LGTASSDAVLPQVMRKLE-HMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKG 342

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 1720397943 429 AASIPSAGLVTMLLILTAVG-LPTEDISLLVAVDWLLDRMRTSVNVVGD 476
Cdd:PRK13027  343 AHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGN 391
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 34-483 8.05e-27

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 113.38  E-value: 8.05e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943  34 KNLLLSLTVF-GVILGAVCGGLLRLA----SPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGL-DAKASGRL 107
Cdd:COG1823    26 KHVSFSKRVFtGLGLGILFGLILQLIygagSPVIKQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLkNASSLGKI 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 108 GTRAMVYYMSTTIIAAVLGVILVLAIHpgnpklkkqlgpgkkndevssLDAfldlirnlfpENLVQAcfqqiqtvtkkvl 187
Cdd:COG1823   106 SGLIIGILLGTTAIAALVGILVALLFG---------------------LTA----------EGLTQG------------- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 188 vappseEANTTKavISMLNETMNEAPEETkiVIKKGLE------FKD--GMNVLGLIG--FFIAF-GIA----MGKMGEQ 252
Cdd:COG1823   142 ------AAETAR--GEALEERLGEVEDLS--LPQQILSfiptnpFADltGARPTSTIAvvIFAAFlGIAalglRRKKPEQ 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 253 AKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICgKIIAIKDLEVVArQLGMYMITVIVGLIIHGGIFLPLIyfVVTRK 332
Cdd:COG1823   212 AETFLKGIDALQAIVMRLVRLVLRLTPYGVLALMT-KVVATSDFADIL-NLGKFVVASYVALIIMFIVHLLLL--ALAGL 287

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 333 NPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTA-LYEAVAAIFIAQMNGV-IL 410
Cdd:COG1823   288 NPLTYFKKVWPVLTFAFTSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCAgIYPAMLAVMIAPTVGInPL 367

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720397943 411 DGGQIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNvVGDSFGAGIV 483
Cdd:COG1823   368 DPSFILTLIAVVTISSFGVAGVGGGATFAALIVLSAMGLPVALAGLLISIEPLIDMGRTALN-VSGSMTAGTV 439
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 231-477 8.17e-15

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 75.47  E-value: 8.17e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 231 NVLGLIGFFIAFGIAMGKMGEQAKlmvEFFNILNEIVMKLVIMIMWYSPLGIACLICgKIIAIKDLEVVArQLGMYMITV 310
Cdd:PRK14695   60 NYIGILSWAVIFGIAMREASKNSK---ELLKTIADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSLA-NYGILLVLL 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 311 IVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQ-AWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLPVGATINMD 389
Cdd:PRK14695  135 VTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAFFTRSSATNIPVNMKLCHD-LGLNPDTYSVSIPLGSTINMA 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 390 GTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRT 469
Cdd:PRK14695  214 GVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIGVIQD 293


                  ....*...
gi 1720397943 470 SVNVVGDS 477
Cdd:PRK14695  294 SCETALNS 301
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 231-449 5.23e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 67.58  E-value: 5.23e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 231 NVLGLIGFFIAFGIAMGKMGEQAKlmvEFFNILNEIVMKLVIMIMWYSPLGIACLICGkIIAIKDLEVVAR--QLGMYMI 308
Cdd:PRK13628  146 NYIGILAWAIGLGLALRHASDTTK---NVVNDLSEAVSQIVKWVIRFAPIGIFGLVAS-TLAETGFSALAGyaQLLAVLV 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 309 T--VIVGLIIHggiflPLIYFVVTRKNPFSF-FAGIFQAWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLPVGAT 385
Cdd:PRK13628  222 GcmLFVALVVN-----PLIVFWKIRRNPYPLvFTCLRESGVTAFFTRSSAANIPVNMALCEK-LGLDEDTYSVSIPLGAT 295

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720397943 386 INMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLvtmLLILTAVGL 449
Cdd:PRK13628  296 INMAGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGVAGGSL---LLIPLACSL 356
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
231-449 1.53e-10

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 63.27  E-value: 1.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 231 NVLGLIGFFIAFGIAMGKMGEQAKLMvefFNILNEIVMKLVIMIMWYSPLGIACLICGkIIAIKDLEVvarqLGMY--MI 308
Cdd:COG3633   145 NYIGILAWAIGLGLALRHASDTTKTV---LSDLSDAVSKIVRWVIRFAPLGIFGLVAS-TVATTGFSA----LLGYahLL 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720397943 309 TVIVG------LIIHggiflPLIYFVVTRKNPFSF-FAGIFQAWITALGTASSAGTLPVTFRCLEDnLGIDKRVTRFVLP 381
Cdd:COG3633   217 AVLVGcmlfvaLVVN-----PLIVFLKIRRNPYPLvFTCLRESGITAFFTRSSAANIPVNMALCEK-LGLDEDTYSVSIP 290

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720397943 382 VGATINMDGtalyeavAAIFIAQMN-------GVILDGGQIVTVSLTATLASIGAASIPSAGLvtmLLILTAVGL 449
Cdd:COG3633   291 LGATINMAG-------AAITITVLTlaavhtlGIEVDLPTALLLSVVAAVSACGASGVAGGSL---LLIPLACSL 355
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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