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Conserved domains on  [gi|1720373267|ref|XP_030102838|]
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protein TALPID3 isoform X3 [Mus musculus]

Protein Classification

TALPID3 domain-containing protein( domain architecture ID 12173090)

TALPID3 domain-containing protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 1-1206 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


:

Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1787.91  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267    1 MPVFKAVKVHLFEDTSTEKNTVAQETETPPNRIDSATTVAAATAAAIATAAPLIKVQSDLEAKVNCVGELLTKLQETDKQ 80
Cdd:pfam15324   26 APVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIKVQSDLEAKVNSVSELLKKLQETDKQ 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267   81 LQRVTEHQASVQSKQEKVHCHDHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDAALKASSLQLGMSTS-RAVGKY--SG 157
Cdd:pfam15324  106 LQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGSALKAVSLQPSSVTSsRAVEKSgnSS 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  158 KLGSPSVGSSVFSHNTFVSKRVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRDGKITKRESPTEEKENMEMNSPKGNV 235
Cdd:pfam15324  186 EDESPAVGSASTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRDAKISKREPPKEEKENMETSSSKGNG 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  236 RLLEQVLNSNECLTRKTESSDITSLTQPKMGWNLEKRDSTETLHSQIFPSSEERGTAQVPVPKYNDVVHDLGQ-KKQASD 314
Cdd:pfam15324  266 RLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPETASVTVQKASDVLQDLGQlKKEMRS 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  315 ML-----------------QIKQSPVTLRLSDHP------------------HNPALLQTTN-TRSVLKDAAKILRGVQN 358
Cdd:pfam15324  346 LLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSPSVLQSTQpPRSMLKDAEKILRQVQN 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  359 NKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEIQDELMRKDYEQKRFDPKNQRNKKAL 438
Cdd:pfam15324  426 NKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEIQDELARKDYEQKRFDQKNRRTAKAQ 505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  439 TM--------SRDIKANNQEKTVNRSVIPRSHYQKQTQEQFTSPPVRNLPASGPQKeRSGLLKSATTLQDEDYMLQIYGK 510
Cdd:pfam15324  506 AAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQK-KEGPLKSTTSLQDEDYLLQVYGK 584

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  511 PVYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIELVKGTKVKSAKTQTDFHAASRMKMDSKIQHPITAlPHADQQYMVSP 590
Cdd:pfam15324  585 AVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKPVKTDSKMQHSVTA-PHQEQQYLFSP 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  591 SREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVTVTTSIPPASRKGNAGVKKPNVAIVEMKSEKKDPP 670
Cdd:pfam15324  664 SREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSSRKPEPGVKKPNIALLEMKSEKKDPP 743

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  671 QLSVQILPSVDIDSVSYSSTDGASSP--PSPKEASLPPLHTWIQTPDFMKVDEEEVPLPGTNFDEVIDVIQEEEKRDEIP 748
Cdd:pfam15324  744 QLTVQVLPSVDIDSVSCSSRDSSPSPvlPSPSEASPPLIQTWIQTPELMKEDEEEVKFPGTNFDEVIDVIQDEEKEDEIP 823

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  749 ECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHPTTDILDKVIERKETLENSLIQWVEQEIMSRIISGLFPLQQQARLDA 828
Cdd:pfam15324  824 EFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVDWVEQEIMARIISGMFPQQAQADPDA 903

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  829 SVSVSEASEPSASDIVAGTSSGALQRMVDARVPVNSDMVSHFVNEALTETIAVMLADREAERQRAAATSVPGDLSGTETN 908
Cdd:pfam15324  904 SVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIMLGDREAQREPPVAASVPGDLPTKETL 983

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  909 LLarvcAPVATPQPTPPCSP-SPVREHVRVKTPDSSPCESDPDaASSIKEIRVEKGSD-MPAVMLVSTPTRTPVATPPPA 986
Cdd:pfam15324  984 LP----TPVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSEHD-FFPVKEIPPEKGADtGPAVSLVITPTVTPIATPPPA 1058

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  987 AALTPTLSETSIDKLKLSSPELPKPWDSGDLPLDEENPNSLQELPHPRAVVMSVA-NEEPESVDFSaqPAPPEPAPSAPL 1065
Cdd:pfam15324 1059 ATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVArDEEPESVVLP--ASPPEPKPLAPP 1136

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267 1066 PEGTKAPSLQRVPSSGSSTLENTLS-TVTETETLDRHISEGEILFSCGQNLATKRPGD--LFLMNINDSLSSTLQDALEM 1142
Cdd:pfam15324 1137 PLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEGEILFSYGQMLAVRALEEggLFLPNLNDSLSSSLHDAQEM 1216

                         1210      1220      1230      1240      1250      1260
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720373267 1143 EDDPPSEGQVIRRPHKKRHEDAIVALLTKQQRELLVSQQE----EDLDNSVGELSEGQRLVLKAAEDI 1206
Cdd:pfam15324 1217 DYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAvyhsEDLENSVGELSEGQRPRLTAAAEN 1284
 
Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 1-1206 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1787.91  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267    1 MPVFKAVKVHLFEDTSTEKNTVAQETETPPNRIDSATTVAAATAAAIATAAPLIKVQSDLEAKVNCVGELLTKLQETDKQ 80
Cdd:pfam15324   26 APVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIKVQSDLEAKVNSVSELLKKLQETDKQ 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267   81 LQRVTEHQASVQSKQEKVHCHDHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDAALKASSLQLGMSTS-RAVGKY--SG 157
Cdd:pfam15324  106 LQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGSALKAVSLQPSSVTSsRAVEKSgnSS 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  158 KLGSPSVGSSVFSHNTFVSKRVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRDGKITKRESPTEEKENMEMNSPKGNV 235
Cdd:pfam15324  186 EDESPAVGSASTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRDAKISKREPPKEEKENMETSSSKGNG 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  236 RLLEQVLNSNECLTRKTESSDITSLTQPKMGWNLEKRDSTETLHSQIFPSSEERGTAQVPVPKYNDVVHDLGQ-KKQASD 314
Cdd:pfam15324  266 RLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPETASVTVQKASDVLQDLGQlKKEMRS 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  315 ML-----------------QIKQSPVTLRLSDHP------------------HNPALLQTTN-TRSVLKDAAKILRGVQN 358
Cdd:pfam15324  346 LLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSPSVLQSTQpPRSMLKDAEKILRQVQN 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  359 NKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEIQDELMRKDYEQKRFDPKNQRNKKAL 438
Cdd:pfam15324  426 NKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEIQDELARKDYEQKRFDQKNRRTAKAQ 505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  439 TM--------SRDIKANNQEKTVNRSVIPRSHYQKQTQEQFTSPPVRNLPASGPQKeRSGLLKSATTLQDEDYMLQIYGK 510
Cdd:pfam15324  506 AAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQK-KEGPLKSTTSLQDEDYLLQVYGK 584

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  511 PVYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIELVKGTKVKSAKTQTDFHAASRMKMDSKIQHPITAlPHADQQYMVSP 590
Cdd:pfam15324  585 AVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKPVKTDSKMQHSVTA-PHQEQQYLFSP 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  591 SREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVTVTTSIPPASRKGNAGVKKPNVAIVEMKSEKKDPP 670
Cdd:pfam15324  664 SREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSSRKPEPGVKKPNIALLEMKSEKKDPP 743

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  671 QLSVQILPSVDIDSVSYSSTDGASSP--PSPKEASLPPLHTWIQTPDFMKVDEEEVPLPGTNFDEVIDVIQEEEKRDEIP 748
Cdd:pfam15324  744 QLTVQVLPSVDIDSVSCSSRDSSPSPvlPSPSEASPPLIQTWIQTPELMKEDEEEVKFPGTNFDEVIDVIQDEEKEDEIP 823

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  749 ECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHPTTDILDKVIERKETLENSLIQWVEQEIMSRIISGLFPLQQQARLDA 828
Cdd:pfam15324  824 EFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVDWVEQEIMARIISGMFPQQAQADPDA 903

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  829 SVSVSEASEPSASDIVAGTSSGALQRMVDARVPVNSDMVSHFVNEALTETIAVMLADREAERQRAAATSVPGDLSGTETN 908
Cdd:pfam15324  904 SVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIMLGDREAQREPPVAASVPGDLPTKETL 983

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  909 LLarvcAPVATPQPTPPCSP-SPVREHVRVKTPDSSPCESDPDaASSIKEIRVEKGSD-MPAVMLVSTPTRTPVATPPPA 986
Cdd:pfam15324  984 LP----TPVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSEHD-FFPVKEIPPEKGADtGPAVSLVITPTVTPIATPPPA 1058

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  987 AALTPTLSETSIDKLKLSSPELPKPWDSGDLPLDEENPNSLQELPHPRAVVMSVA-NEEPESVDFSaqPAPPEPAPSAPL 1065
Cdd:pfam15324 1059 ATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVArDEEPESVVLP--ASPPEPKPLAPP 1136

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267 1066 PEGTKAPSLQRVPSSGSSTLENTLS-TVTETETLDRHISEGEILFSCGQNLATKRPGD--LFLMNINDSLSSTLQDALEM 1142
Cdd:pfam15324 1137 PLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEGEILFSYGQMLAVRALEEggLFLPNLNDSLSSSLHDAQEM 1216

                         1210      1220      1230      1240      1250      1260
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720373267 1143 EDDPPSEGQVIRRPHKKRHEDAIVALLTKQQRELLVSQQE----EDLDNSVGELSEGQRLVLKAAEDI 1206
Cdd:pfam15324 1217 DYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAvyhsEDLENSVGELSEGQRPRLTAAAEN 1284
 
Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 1-1206 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1787.91  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267    1 MPVFKAVKVHLFEDTSTEKNTVAQETETPPNRIDSATTVAAATAAAIATAAPLIKVQSDLEAKVNCVGELLTKLQETDKQ 80
Cdd:pfam15324   26 APVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIKVQSDLEAKVNSVSELLKKLQETDKQ 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267   81 LQRVTEHQASVQSKQEKVHCHDHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDAALKASSLQLGMSTS-RAVGKY--SG 157
Cdd:pfam15324  106 LQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGSALKAVSLQPSSVTSsRAVEKSgnSS 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  158 KLGSPSVGSSVFSHNTFVSKRVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRDGKITKRESPTEEKENMEMNSPKGNV 235
Cdd:pfam15324  186 EDESPAVGSASTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRDAKISKREPPKEEKENMETSSSKGNG 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  236 RLLEQVLNSNECLTRKTESSDITSLTQPKMGWNLEKRDSTETLHSQIFPSSEERGTAQVPVPKYNDVVHDLGQ-KKQASD 314
Cdd:pfam15324  266 RLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPETASVTVQKASDVLQDLGQlKKEMRS 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  315 ML-----------------QIKQSPVTLRLSDHP------------------HNPALLQTTN-TRSVLKDAAKILRGVQN 358
Cdd:pfam15324  346 LLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSPSVLQSTQpPRSMLKDAEKILRQVQN 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  359 NKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEIQDELMRKDYEQKRFDPKNQRNKKAL 438
Cdd:pfam15324  426 NKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEIQDELARKDYEQKRFDQKNRRTAKAQ 505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  439 TM--------SRDIKANNQEKTVNRSVIPRSHYQKQTQEQFTSPPVRNLPASGPQKeRSGLLKSATTLQDEDYMLQIYGK 510
Cdd:pfam15324  506 AAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQK-KEGPLKSTTSLQDEDYLLQVYGK 584

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  511 PVYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIELVKGTKVKSAKTQTDFHAASRMKMDSKIQHPITAlPHADQQYMVSP 590
Cdd:pfam15324  585 AVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKPVKTDSKMQHSVTA-PHQEQQYLFSP 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  591 SREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVTVTTSIPPASRKGNAGVKKPNVAIVEMKSEKKDPP 670
Cdd:pfam15324  664 SREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSSRKPEPGVKKPNIALLEMKSEKKDPP 743

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  671 QLSVQILPSVDIDSVSYSSTDGASSP--PSPKEASLPPLHTWIQTPDFMKVDEEEVPLPGTNFDEVIDVIQEEEKRDEIP 748
Cdd:pfam15324  744 QLTVQVLPSVDIDSVSCSSRDSSPSPvlPSPSEASPPLIQTWIQTPELMKEDEEEVKFPGTNFDEVIDVIQDEEKEDEIP 823

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  749 ECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHPTTDILDKVIERKETLENSLIQWVEQEIMSRIISGLFPLQQQARLDA 828
Cdd:pfam15324  824 EFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVDWVEQEIMARIISGMFPQQAQADPDA 903

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  829 SVSVSEASEPSASDIVAGTSSGALQRMVDARVPVNSDMVSHFVNEALTETIAVMLADREAERQRAAATSVPGDLSGTETN 908
Cdd:pfam15324  904 SVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIMLGDREAQREPPVAASVPGDLPTKETL 983

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  909 LLarvcAPVATPQPTPPCSP-SPVREHVRVKTPDSSPCESDPDaASSIKEIRVEKGSD-MPAVMLVSTPTRTPVATPPPA 986
Cdd:pfam15324  984 LP----TPVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSEHD-FFPVKEIPPEKGADtGPAVSLVITPTVTPIATPPPA 1058

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267  987 AALTPTLSETSIDKLKLSSPELPKPWDSGDLPLDEENPNSLQELPHPRAVVMSVA-NEEPESVDFSaqPAPPEPAPSAPL 1065
Cdd:pfam15324 1059 ATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVArDEEPESVVLP--ASPPEPKPLAPP 1136

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720373267 1066 PEGTKAPSLQRVPSSGSSTLENTLS-TVTETETLDRHISEGEILFSCGQNLATKRPGD--LFLMNINDSLSSTLQDALEM 1142
Cdd:pfam15324 1137 PLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEGEILFSYGQMLAVRALEEggLFLPNLNDSLSSSLHDAQEM 1216

                         1210      1220      1230      1240      1250      1260
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720373267 1143 EDDPPSEGQVIRRPHKKRHEDAIVALLTKQQRELLVSQQE----EDLDNSVGELSEGQRLVLKAAEDI 1206
Cdd:pfam15324 1217 DYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAvyhsEDLENSVGELSEGQRPRLTAAAEN 1284
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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