NCBI Conserved Domain Search

Conserved domains on [gi|1720372804|ref|XP_030102739|]

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RNA-binding protein 25 isoform X5 [Mus musculus]

Protein Classification

PWI domain-containing protein( domain architecture ID 10645659)

PWI domain-containing protein may function as a splicing factor; similar to Saccharomyces cerevisiae U1 small nuclear ribonucleoprotein component SNU71, a component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA

CATH: 1.20.1390.10

Gene Ontology: GO:0006397|GO:0003676

PubMed: 10322432|12600940

SCOP: 4000671

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

PWI

smart00311

PWI, domain in splicing factors;

554-627

1.12e-25

PWI, domain in splicing factors;

Pssm-ID: 214609 [Multi-domain] Cd Length: 74 Bit Score: 100.50 E-value: 1.12e-25

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720372804  554 DSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEA 627
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQHKGPQAKLLQINLTGFEDAEEFVDKLWRLLIFELKN 74

Name

Accession

Description

Interval

E-value

PWI

smart00311

PWI, domain in splicing factors;

554-627

1.12e-25

PWI, domain in splicing factors;

Pssm-ID: 214609 [Multi-domain] Cd Length: 74 Bit Score: 100.50 E-value: 1.12e-25

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720372804  554 DSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEA 627
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQHKGPQAKLLQINLTGFEDAEEFVDKLWRLLIFELKN 74

PWI

pfam01480

PWI domain;

562-629

8.25e-13

PWI domain;

Pssm-ID: 460224 [Multi-domain] Cd Length: 71 Bit Score: 63.68 E-value: 8.25e-13

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720372804 562 IRPWINKKIIEYIGEEEATLVDFVCSKV-MAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEAKK 629
Cdd:pfam01480   3 LKPWIEKKITEILGFEDDVVVEYVVNLLeEKFPDPKELQIQLTGFLDKDAAKFVKELWKLLLSAQESPS 71

Name

Accession

Description

Interval

E-value

PWI

smart00311

PWI, domain in splicing factors;

554-627

1.12e-25

PWI, domain in splicing factors;

Pssm-ID: 214609 [Multi-domain] Cd Length: 74 Bit Score: 100.50 E-value: 1.12e-25

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720372804  554 DSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEA 627
Cdd:smart00311   1 LSKLKLDEIKPWITKKVIEFLGFEEDTLVEFILSQIRQHKGPQAKLLQINLTGFEDAEEFVDKLWRLLIFELKN 74

PWI

pfam01480

PWI domain;

562-629

8.25e-13

PWI domain;

Pssm-ID: 460224 [Multi-domain] Cd Length: 71 Bit Score: 63.68 E-value: 8.25e-13

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720372804 562 IRPWINKKIIEYIGEEEATLVDFVCSKV-MAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEAKK 629
Cdd:pfam01480   3 LKPWIEKKITEILGFEDDVVVEYVVNLLeEKFPDPKELQIQLTGFLDKDAAKFVKELWKLLLSAQESPS 71

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01