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Conserved domains on  [gi|1720364659|ref|XP_030101539|]
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BCAS3 microtubule associated cell migration factor isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BCAS3 super family cl13871
Breast carcinoma amplified sequence 3; This domain family is found in eukaryotes, and is ...
534-777 5.20e-18

Breast carcinoma amplified sequence 3; This domain family is found in eukaryotes, and is typically between 229 and 245 amino acids in length. The proteins in this family have been shown to be proto-oncogenes implicated in the development of breast cancer.


The actual alignment was detected with superfamily member pfam12490:

Pssm-ID: 463605  Cd Length: 234  Bit Score: 84.29  E-value: 5.20e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364659  534 PSLMVVTPLAQIKQPMT--LGTITkrtgpylfGAGCFSikapckvkSPPQISPSKSmggefcVAAVFGTSRSWFANNAGL 611
Cdd:pfam12490    1 PPPVTLSVVSRIKNGNSgwLNTVS--------GAAAAA--------TGKVSSPSGA------IASVFHNCKGWSYGSVNS 58
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364659  612 KREKdqskqvVVESLYIISCYGTLVEHMIEPRP----------ISTAPKISDDTPLEIMTSPRASWTLVRTPQWNELQPP 681
Cdd:pfam12490   59 SALK------PLEHLLVFSPSGHVIQYALRPSSggesgdssrgGGISYESMQETELRVVVEPIQWWDVCRRSNWPEREDP 132
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364659  682 FNANHPLllaaeavqYYQLLLAGSLPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGpHRRLWMGPQFHFKT 761
Cdd:pfam12490  133 LSSNSDI--------YGDAGSSEDSKVKSNSIVPSNNGVDGKESLKSEERHHLYLSNAELQMHSG-HTPLWQKSKISFQV 203
                          250
                   ....*....|....*.
gi 1720364659  762 IQTSGQTTVISTSSSV 777
Cdd:pfam12490  204 MVLPTAEEDNSGNSSG 219
 
Name Accession Description Interval E-value
BCAS3 pfam12490
Breast carcinoma amplified sequence 3; This domain family is found in eukaryotes, and is ...
534-777 5.20e-18

Breast carcinoma amplified sequence 3; This domain family is found in eukaryotes, and is typically between 229 and 245 amino acids in length. The proteins in this family have been shown to be proto-oncogenes implicated in the development of breast cancer.


Pssm-ID: 463605  Cd Length: 234  Bit Score: 84.29  E-value: 5.20e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364659  534 PSLMVVTPLAQIKQPMT--LGTITkrtgpylfGAGCFSikapckvkSPPQISPSKSmggefcVAAVFGTSRSWFANNAGL 611
Cdd:pfam12490    1 PPPVTLSVVSRIKNGNSgwLNTVS--------GAAAAA--------TGKVSSPSGA------IASVFHNCKGWSYGSVNS 58
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364659  612 KREKdqskqvVVESLYIISCYGTLVEHMIEPRP----------ISTAPKISDDTPLEIMTSPRASWTLVRTPQWNELQPP 681
Cdd:pfam12490   59 SALK------PLEHLLVFSPSGHVIQYALRPSSggesgdssrgGGISYESMQETELRVVVEPIQWWDVCRRSNWPEREDP 132
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364659  682 FNANHPLllaaeavqYYQLLLAGSLPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGpHRRLWMGPQFHFKT 761
Cdd:pfam12490  133 LSSNSDI--------YGDAGSSEDSKVKSNSIVPSNNGVDGKESLKSEERHHLYLSNAELQMHSG-HTPLWQKSKISFQV 203
                          250
                   ....*....|....*.
gi 1720364659  762 IQTSGQTTVISTSSSV 777
Cdd:pfam12490  204 MVLPTAEEDNSGNSSG 219
 
Name Accession Description Interval E-value
BCAS3 pfam12490
Breast carcinoma amplified sequence 3; This domain family is found in eukaryotes, and is ...
534-777 5.20e-18

Breast carcinoma amplified sequence 3; This domain family is found in eukaryotes, and is typically between 229 and 245 amino acids in length. The proteins in this family have been shown to be proto-oncogenes implicated in the development of breast cancer.


Pssm-ID: 463605  Cd Length: 234  Bit Score: 84.29  E-value: 5.20e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364659  534 PSLMVVTPLAQIKQPMT--LGTITkrtgpylfGAGCFSikapckvkSPPQISPSKSmggefcVAAVFGTSRSWFANNAGL 611
Cdd:pfam12490    1 PPPVTLSVVSRIKNGNSgwLNTVS--------GAAAAA--------TGKVSSPSGA------IASVFHNCKGWSYGSVNS 58
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364659  612 KREKdqskqvVVESLYIISCYGTLVEHMIEPRP----------ISTAPKISDDTPLEIMTSPRASWTLVRTPQWNELQPP 681
Cdd:pfam12490   59 SALK------PLEHLLVFSPSGHVIQYALRPSSggesgdssrgGGISYESMQETELRVVVEPIQWWDVCRRSNWPEREDP 132
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364659  682 FNANHPLllaaeavqYYQLLLAGSLPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGpHRRLWMGPQFHFKT 761
Cdd:pfam12490  133 LSSNSDI--------YGDAGSSEDSKVKSNSIVPSNNGVDGKESLKSEERHHLYLSNAELQMHSG-HTPLWQKSKISFQV 203
                          250
                   ....*....|....*.
gi 1720364659  762 IQTSGQTTVISTSSSV 777
Cdd:pfam12490  204 MVLPTAEEDNSGNSSG 219
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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