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Conserved domains on  [gi|1720364114|ref|XP_030101409|]
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envoplakin isoform X3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SH3_10 pfam17902
SH3 domain; This entry represents an SH3 domain.
 433-497 8.99e-25

SH3 domain; This entry represents an SH3 domain.


:

Pssm-ID: 407754  Cd Length: 65  Bit Score: 98.87  E-value: 8.99e-25
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720364114  433 PLPQRRNPSKQPLHVDSICDWDSGEVQLLRGERYTLKDNADPYTWLVQGPGGETKSAPAACLCIP 497
Cdd:pfam17902    1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 880-1675 9.77e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.15  E-value: 9.77e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  880 ESIQAQEKnLAKAYTEVaaaeQQQLRQLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVA 959
Cdd:TIGR02168  203 KSLERQAE-KAERYKEL----KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  960 EVQRDLEEQRQRLLQLRTQQpvARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKT 1039
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1040 MQPHLLTKEVTQIERDPG---LDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDL 1116
Cdd:TIGR02168  356 LEAELEELEAELEELESRleeLEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1117 EMVKAA-QTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEpkvivkevkkveqdpgllKEASRLRSLLEeeknn 1195
Cdd:TIGR02168  436 KELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAE------------------RELAQLQARLD----- 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1196 nvALARELQELQEKYR----VVEKQKPKVQLQERVSEIFQVLPETEQEIRR-LRAQLQE-TGSKKSGVEQEVEKLLP--- 1266
Cdd:TIGR02168  493 --SLERLQENLEGFSEgvkaLLKNQSGLSGILGVLSELISVDEGYEAAIEAaLGGRLQAvVVENLNAAKKAIAFLKQnel 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1267 ------ELEVLRAQKPVVEYKEVTQEV-------VRHEKNPEVLRE-----------IDRLKAQLNELVNTNGRsqEQLI 1322
Cdd:TIGR02168  571 grvtflPLDSIKGTEIQGNDREILKNIegflgvaKDLVKFDPKLRKalsyllggvlvVDDLDNALELAKKLRPG--YRIV 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1323 RLQGERDEWK----RERSKVETKMVSKevvrhekdpvlEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEE 1398
Cdd:TIGR02168  649 TLDGDLVRPGgvitGGSAKTNSSILER-----------RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1399 QIVVQEVVVTQKDpkLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLsfEEDRSKKLAAERELRQLTLKIQE 1478
Cdd:TIGR02168  718 RKELEELSRQISA--LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL--EEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1479 LEKRPPALQEKIimeevvklekdpdlerstEALRRELDQEKNRVTELHRECQGLQVQVDLLQK--TKSQEKTIYKEVIRV 1556
Cdd:TIGR02168  794 LKEELKALREAL------------------DELRAELTLLNEEAANLRERLESLERRIAATERrlEDLEEQIEELSEDIE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1557 EKDPVLEGERARVWEI---LNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELE 1633
Cdd:TIGR02168  856 SLAAEIEELEELIEELeseLEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1720364114 1634 QQKQQKARQLQEEGRL-------LSQKTESERQKAAQRsqaVTQLEAAI 1675
Cdd:TIGR02168  936 VRIDNLQERLSEEYSLtleeaeaLENKIEDDEEEARRR---LKRLENKI 981
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
 1888-1926 5.93e-10

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


:

Pssm-ID: 459901  Cd Length: 39  Bit Score: 56.18  E-value: 5.93e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1720364114 1888 LLEAQAATGGIVDLLSRERYSVHKAVERGLIENTSTQRL 1926
Cdd:pfam00681    1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1924-1961 3.43e-07

Plectin repeat;


:

Pssm-ID: 197605  Cd Length: 38  Bit Score: 48.25  E-value: 3.43e-07
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1720364114  1924 QRLLNAQKAFTGIEDPVTRKRLSVGEAIQKGWMPQESV 1961
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
YhaN super family cl34808
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
666-1047 9.22e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


The actual alignment was detected with superfamily member COG4717:

Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 9.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  666 LEKQIQEADRVIQGFEAALALEGPVPEGSgALQERVSELQRQRKELLQQQACVLGLHRQLKATEHACSALQNNFQEFCQD 745
Cdd:COG4717    107 LEAELEELREELEKLEKLLQLLPLYQELE-ALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQ 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  746 L-PRQQRQVRALTDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDNLSSWLEQLPHHR---------------------- 802
Cdd:COG4717    186 LsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlkearlllliaaallallglg 265

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  803 VQPSDGPSQISYKLQAQKRLI----------QEILGREQDQATVSRLTRDLQEALQDYELQADTYRCSLEPALAVSAPKR 872
Cdd:COG4717    266 GSLLSLILTIAGVLFLVLGLLallflllareKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDR 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  873 LRviSLQESIQAQEKNLAKAYTEVAAAEQQQLRQL-------EFAKKMLRKKELDEDIQAIHSARQ-----GSGSPAHAR 940
Cdd:COG4717    346 IE--ELQELLREAEELEEELQLEELEQEIAALLAEagvedeeELRAALEQAEEYQELKEELEELEEqleelLGELEELLE 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  941 TAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQqpVARLEEKEVVEfyrdpQLESNLSQAASRVEEEGKRRARLQ 1020
Cdd:COG4717    424 ALDEEELEEELEELEEELEELEEELEELREELAELEAE--LEQLEEDGELA-----ELLQELEELKAELRELAEEWAALK 496

                          410       420
                   ....*....|....*....|....*..
gi 1720364114 1021 AELEAVAQkvvHLEGKRKTMQPHLLTK 1047
Cdd:COG4717    497 LALELLEE---AREEYREERLPPVLER 520
SPEC super family cl02488
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
 302-387 1.62e-05

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


The actual alignment was detected with superfamily member cd00176:

Pssm-ID: 413338 [Multi-domain]  Cd Length: 213  Bit Score: 48.21  E-value: 1.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  302 QHELLAQERSINQLEDDADRMVELGHPAIGPIQVHQEALKMEWQNFLNLCICQESQLQRVEDYRRFQEEADSVSQTLAKL 381
Cdd:cd00176     46 EAELAAHEERVEALNELGEQLIEEGHPDAEEIQERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEK 125


                   ....*.
gi 1720364114  382 SSNLDT 387
Cdd:cd00176    126 EAALAS 131
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
 1967-2002 2.13e-05

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


:

Pssm-ID: 459901  Cd Length: 39  Bit Score: 43.09  E-value: 2.13e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1720364114 1967 VQHLTGGLIDPKRTGRIPVPQAVLCGMISEDLGQLL 2002
Cdd:pfam00681    4 AQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
 1718-1746 5.62e-04

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


:

Pssm-ID: 459901  Cd Length: 39  Bit Score: 39.23  E-value: 5.62e-04
                           10        20
                   ....*....|....*....|....*....
gi 1720364114 1718 ILEPETGNDMSPYEAYKRGVIDRGQYLQL 1746
Cdd:pfam00681   11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1850-1885 1.25e-03

Plectin repeat;


:

Pssm-ID: 197605  Cd Length: 38  Bit Score: 38.23  E-value: 1.25e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1720364114  1850 LTEDSFPIAGIYDTTTDNKCSIKAAVAKNMLDPITG 1885
Cdd:smart00250    3 LLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
 
Name Accession Description Interval E-value
SH3_10 pfam17902
SH3 domain; This entry represents an SH3 domain.
 433-497 8.99e-25

SH3 domain; This entry represents an SH3 domain.


Pssm-ID: 407754  Cd Length: 65  Bit Score: 98.87  E-value: 8.99e-25
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720364114  433 PLPQRRNPSKQPLHVDSICDWDSGEVQLLRGERYTLKDNADPYTWLVQGPGGETKSAPAACLCIP 497
Cdd:pfam17902    1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 880-1675 9.77e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.15  E-value: 9.77e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  880 ESIQAQEKnLAKAYTEVaaaeQQQLRQLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVA 959
Cdd:TIGR02168  203 KSLERQAE-KAERYKEL----KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  960 EVQRDLEEQRQRLLQLRTQQpvARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKT 1039
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1040 MQPHLLTKEVTQIERDPG---LDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDL 1116
Cdd:TIGR02168  356 LEAELEELEAELEELESRleeLEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1117 EMVKAA-QTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEpkvivkevkkveqdpgllKEASRLRSLLEeeknn 1195
Cdd:TIGR02168  436 KELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAE------------------RELAQLQARLD----- 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1196 nvALARELQELQEKYR----VVEKQKPKVQLQERVSEIFQVLPETEQEIRR-LRAQLQE-TGSKKSGVEQEVEKLLP--- 1266
Cdd:TIGR02168  493 --SLERLQENLEGFSEgvkaLLKNQSGLSGILGVLSELISVDEGYEAAIEAaLGGRLQAvVVENLNAAKKAIAFLKQnel 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1267 ------ELEVLRAQKPVVEYKEVTQEV-------VRHEKNPEVLRE-----------IDRLKAQLNELVNTNGRsqEQLI 1322
Cdd:TIGR02168  571 grvtflPLDSIKGTEIQGNDREILKNIegflgvaKDLVKFDPKLRKalsyllggvlvVDDLDNALELAKKLRPG--YRIV 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1323 RLQGERDEWK----RERSKVETKMVSKevvrhekdpvlEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEE 1398
Cdd:TIGR02168  649 TLDGDLVRPGgvitGGSAKTNSSILER-----------RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1399 QIVVQEVVVTQKDpkLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLsfEEDRSKKLAAERELRQLTLKIQE 1478
Cdd:TIGR02168  718 RKELEELSRQISA--LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL--EEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1479 LEKRPPALQEKIimeevvklekdpdlerstEALRRELDQEKNRVTELHRECQGLQVQVDLLQK--TKSQEKTIYKEVIRV 1556
Cdd:TIGR02168  794 LKEELKALREAL------------------DELRAELTLLNEEAANLRERLESLERRIAATERrlEDLEEQIEELSEDIE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1557 EKDPVLEGERARVWEI---LNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELE 1633
Cdd:TIGR02168  856 SLAAEIEELEELIEELeseLEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1720364114 1634 QQKQQKARQLQEEGRL-------LSQKTESERQKAAQRsqaVTQLEAAI 1675
Cdd:TIGR02168  936 VRIDNLQERLSEEYSLtleeaeaLENKIEDDEEEARRR---LKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1126-1674 5.09e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.70  E-value: 5.09e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1126 RLQIEEDAARRKGAKETVAKIQARIKDLEQAISSvepkvivkevkkveqdpgLLKEASRLRSLLEEEKNNNVALARELQE 1205
Cdd:COG1196    224 ELEAELLLLKLRELEAELEELEAELEELEAELEE------------------LEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1206 LQEKYRVVEKQKPKVQ-----LQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVEY 1280
Cdd:COG1196    286 AQAEEYELLAELARLEqdiarLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1281 KEVTQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDPVLEKEA 1360
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1361 ER-------------LRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRsLDE 1427
Cdd:COG1196    446 EAaeeeaeleeeeeaLLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG-LAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1428 EVGRRRQLELEVRQ---------LGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKL 1498
Cdd:COG1196    525 AVAVLIGVEAAYEAaleaalaaaLQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1499 EKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIykevirVEKDPVLEGERARvwEILNRERA 1578
Cdd:COG1196    605 ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG------GSAGGSLTGGSRR--ELLAALLE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1579 ARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESER 1658
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756

                          570
                   ....*....|....*.
gi 1720364114 1659 QKAAQRSQAVTQLEAA 1674
Cdd:COG1196    757 PEPPDLEELERELERL 772
PTZ00121 PTZ00121
MAEBL; Provisional
 1117-1730 1.07e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 90.59  E-value: 1.07e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1117 EMVKAAQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNN 1196
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1197 VALARELQELQEKyRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKP 1276
Cdd:PTZ00121  1289 KKKADEAKKAEEK-KKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1277 VVEYK--EVTQEVVRHEKNPEVLREIDRLKAQLNElvntNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDP 1354
Cdd:PTZ00121  1368 AAEKKkeEAKKKADAAKKKAEEKKKADEAKKKAEE----DKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEA 1443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1355 VLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDP-KLREEHSRLSRSLDEEVGRRR 1433
Cdd:PTZ00121  1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEaKKAAEAKKKADEAKKAEEAKK 1523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1434 QLELEVRQLGARVEE----EEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQ--------EKIIMEEVVKLEKD 1501
Cdd:PTZ00121  1524 ADEAKKAEEAKKADEakkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRkaeeakkaEEARIEEVMKLYEE 1603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1502 PDLERSTEAlrRELDQEKNRVTELHREcQGLQVQVDLLQKTKSQEKTIYKEV--------IRVEKDPVLEGERARVWEIL 1573
Cdd:PTZ00121  1604 EKKMKAEEA--KKAEEAKIKAEELKKA-EEEKKKVEQLKKKEAEEKKKAEELkkaeeenkIKAAEEAKKAEEDKKKAEEA 1680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1574 NRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKqQKARQLQEEgrllsqk 1653
Cdd:PTZ00121  1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDK-KKAEEAKKD------- 1752

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720364114 1654 tESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLStkicilepETGNDMSPY 1730
Cdd:PTZ00121  1753 -EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANII--------EGGKEGNLV 1820
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 948-1645 9.75e-11

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 67.51  E-value: 9.75e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  948 KTQLEEERKRVAEVQRDLEEQRQRLL-QLRTQQPV-ARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAElea 1025
Cdd:pfam01576   21 QQKAESELKELEKKHQQLCEEKNALQeQLQAETELcAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNE--- 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1026 vaqkvvhlegkRKTMQPHLLTkevtqierdpgLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALE------QKEMN 1099
Cdd:pfam01576   98 -----------KKKMQQHIQD-----------LEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEdqnsklSKERK 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1100 VKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEedaarrkgakETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEqdpgLL 1179
Cdd:pfam01576  156 LLEERISEFTSNLAEEEEKAKSLSKLKNKHE----------AMISDLEERLKKEEKGRQELEKAKRKLEGESTD----LQ 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1180 KEASRLRSLLEEEKNNNVALARELQELQEkyRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQ 1259
Cdd:pfam01576  222 EQIAELQAQIAELRAQLAKKEEELQAALA--RLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGE 299

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1260 EVEKLLPELE----VLRAQKPVVEYKEvtQEVVRHEKNPEvlREIDRLKAQLNELvntNGRSQEQLIRLQGERDEWKRER 1335
Cdd:pfam01576  300 ELEALKTELEdtldTTAAQQELRSKRE--QEVTELKKALE--EETRSHEAQLQEM---RQKHTQALEELTEQLEQAKRNK 372

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1336 SKVETKMVSKEVVRHEkdpvLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQE----------- 1404
Cdd:pfam01576  373 ANLEKAKQALESENAE----LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKlqselesvssl 448

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1405 -VVVTQKDPKLREEHSRLSRSL-------DEEVGRRRQLELEVRQLgarvEEEEARL--SFEEDRSKKLAAERELRQLTL 1474
Cdd:pfam01576  449 lNEAEGKNIKLSKDVSSLESQLqdtqellQEETRQKLNLSTRLRQL----EDERNSLqeQLEEEEEAKRNVERQLSTLQA 524

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1475 KIQELEKRppaLQEKIIMEEVVKlEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVI 1554
Cdd:pfam01576  525 QLSDMKKK---LEEDAGTLEALE-EGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLE 600

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1555 RVEK--DPVLEGERARVWEILN-RERAARKGREEDVRSL---------QERIDRAEALRRSWSREEAELQRARDQASQDC 1622
Cdd:pfam01576  601 KKQKkfDQMLAEEKAISARYAEeRDRAEAEAREKETRALslaraleeaLEAKEELERTNKQLRAEMEDLVSSKDDVGKNV 680

                          730       740
                   ....*....|....*....|...
gi 1720364114 1623 GRLQRQLRELEQQKQQKARQLQE 1645
Cdd:pfam01576  681 HELERSKRALEQQVEEMKTQLEE 703
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
 1888-1926 5.93e-10

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 56.18  E-value: 5.93e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1720364114 1888 LLEAQAATGGIVDLLSRERYSVHKAVERGLIENTSTQRL 1926
Cdd:pfam00681    1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
PLEC smart00250
Plectin repeat;
1924-1961 3.43e-07

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 48.25  E-value: 3.43e-07
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1720364114  1924 QRLLNAQKAFTGIEDPVTRKRLSVGEAIQKGWMPQESV 1961
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
PLEC smart00250
Plectin repeat;
1886-1919 1.02e-06

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 47.09  E-value: 1.02e-06
                            10        20        30
                    ....*....|....*....|....*....|....
gi 1720364114  1886 QKLLEAQAATGGIVDLLSRERYSVHKAVERGLIE 1919
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLID 34
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
666-1047 9.22e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 9.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  666 LEKQIQEADRVIQGFEAALALEGPVPEGSgALQERVSELQRQRKELLQQQACVLGLHRQLKATEHACSALQNNFQEFCQD 745
Cdd:COG4717    107 LEAELEELREELEKLEKLLQLLPLYQELE-ALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQ 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  746 L-PRQQRQVRALTDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDNLSSWLEQLPHHR---------------------- 802
Cdd:COG4717    186 LsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlkearlllliaaallallglg 265

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  803 VQPSDGPSQISYKLQAQKRLI----------QEILGREQDQATVSRLTRDLQEALQDYELQADTYRCSLEPALAVSAPKR 872
Cdd:COG4717    266 GSLLSLILTIAGVLFLVLGLLallflllareKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDR 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  873 LRviSLQESIQAQEKNLAKAYTEVAAAEQQQLRQL-------EFAKKMLRKKELDEDIQAIHSARQ-----GSGSPAHAR 940
Cdd:COG4717    346 IE--ELQELLREAEELEEELQLEELEQEIAALLAEagvedeeELRAALEQAEEYQELKEELEELEEqleelLGELEELLE 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  941 TAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQqpVARLEEKEVVEfyrdpQLESNLSQAASRVEEEGKRRARLQ 1020
Cdd:COG4717    424 ALDEEELEEELEELEEELEELEEELEELREELAELEAE--LEQLEEDGELA-----ELLQELEELKAELRELAEEWAALK 496

                          410       420
                   ....*....|....*....|....*..
gi 1720364114 1021 AELEAVAQkvvHLEGKRKTMQPHLLTK 1047
Cdd:COG4717    497 LALELLEE---AREEYREERLPPVLER 520
SPEC cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
 302-387 1.62e-05

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


Pssm-ID: 238103 [Multi-domain]  Cd Length: 213  Bit Score: 48.21  E-value: 1.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  302 QHELLAQERSINQLEDDADRMVELGHPAIGPIQVHQEALKMEWQNFLNLCICQESQLQRVEDYRRFQEEADSVSQTLAKL 381
Cdd:cd00176     46 EAELAAHEERVEALNELGEQLIEEGHPDAEEIQERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEK 125


                   ....*.
gi 1720364114  382 SSNLDT 387
Cdd:cd00176    126 EAALAS 131
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
 1967-2002 2.13e-05

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 43.09  E-value: 2.13e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1720364114 1967 VQHLTGGLIDPKRTGRIPVPQAVLCGMISEDLGQLL 2002
Cdd:pfam00681    4 AQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
 1718-1746 5.62e-04

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 39.23  E-value: 5.62e-04
                           10        20
                   ....*....|....*....|....*....
gi 1720364114 1718 ILEPETGNDMSPYEAYKRGVIDRGQYLQL 1746
Cdd:pfam00681   11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
SPEC smart00150
Spectrin repeats;
302-359 1.14e-03

Spectrin repeats;


Pssm-ID: 197544 [Multi-domain]  Cd Length: 101  Bit Score: 40.39  E-value: 1.14e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720364114   302 QHELLAQERSINQLEDDADRMVELGHPAIGPIQVHQEALKMEWQNFLNLCICQESQLQ 359
Cdd:smart00150   44 EAELEAHEERVEALNELGEQLIEEGHPDAEEIEERLEELNERWEELKELAEERRQKLE 101
PLEC smart00250
Plectin repeat;
1850-1885 1.25e-03

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 38.23  E-value: 1.25e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1720364114  1850 LTEDSFPIAGIYDTTTDNKCSIKAAVAKNMLDPITG 1885
Cdd:smart00250    3 LLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 502-1098 1.90e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  502 EAVAKASRLATELQTLKQKLSTEKNRLKAAAVEHLQPGQQAPAGSAPADP--QGQTLLSQMTQLDGDLGQIERQVLSWAR 579
Cdd:TIGR00618  331 AAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHihTLQQQKTTLTQKLQSLCKELDILQREQA 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  580 SPLSQSSSLKDLEGRIHSCEGTAQRLQSLGAEKEAAQQEceAFLSTKPTGSAALQLPVVLNSVKNRYNDVQSLCHLYGEK 659
Cdd:TIGR00618  411 TIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITC--TAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRK 488

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  660 AKAALGLEKQIQEADRVIQGFEAALALEGPVPEGSGALQERVSELQRQRKELLQQqacvlglhrqLKATEHACSALQNNF 739
Cdd:TIGR00618  489 KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETS----------EEDVYHQLTSERKQR 558

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  740 QEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKIVQDasltyqqlrnsrdnLSSWLEQLPHHRVQpsdgpsqisyklqaq 819
Cdd:TIGR00618  559 ASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVR--------------LQDLTEKLSEAEDM--------------- 609

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  820 KRLIQEILGREqdqatvsrltrdLQEALQDYELQADTYRCSLEPALAVSAPKRLRVISLQE-------SIQAQEKNLAKA 892
Cdd:TIGR00618  610 LACEQHALLRK------------LQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQErvrehalSIRVLPKELLAS 677

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  893 YTEVAAAEQQQLRQLEFAKKMLRKKelDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRL 972
Cdd:TIGR00618  678 RQLALQKMQSEKEQLTYWKEMLAQC--QTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTV 755

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  973 LQLRTQQPvARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRkTMQPHLLTKEVTQi 1052
Cdd:TIGR00618  756 LKARTEAH-FNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDIL-NLQCETLVQEEEQ- 832

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1720364114 1053 erdpgLDSQVTQLHSEMQRLRGENGVLTARLEELkdELLALEQKEM 1098
Cdd:TIGR00618  833 -----FLSRLEEKSATLGEITHQLLKYEECSKQL--AQLTQEQAKI 871
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 1183-1563 2.60e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 42.69  E-value: 2.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1183 SRLRSLLEEEKN-NNVALARELQELQEKY---RVVEKQKPKVQLQERV-SEIFQVLPETEQEIRRLRAQLQETGSKksgV 1257
Cdd:NF033838    72 SEIQKSLDKRKHtQNVALNKKLSDIKTEYlyeLNVLKEKSEAELTSKTkKELDAAFEQFKKDTLEPGKKVAEATKK---V 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1258 EQEVEKLLPELEVLRAQKPVVEYKevTQEVVRHEKNPEVLR-EIDRLKAQLNElvntngrsqeqlirlqgERDEWKRERS 1336
Cdd:NF033838   149 EEAEKKAKDQKEEDRRNYPTNTYK--TLELEIAESDVEVKKaELELVKEEAKE-----------------PRDEEKIKQA 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1337 KVETKMVSKEVVRHEKDPVLEKEAERLRQEVREAVQRRRATEDAVYELQNKLllleRRRPEEQIVVQEVVVTQKDPKLRE 1416
Cdd:NF033838   210 KAKVESKKAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKP----KRRAKRGVLGEPATPDKKENDAKS 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1417 EHSrlsrSLDEEVGRRRQLELEVRQLGA--RVEEEE--ARLSFEEDRskklaaeRELRQLTLKIQELEkrppalqekiIM 1492
Cdd:NF033838   286 SDS----SVGEETLPSPSLKPEKKVAEAekKVEEAKkkAKDQKEEDR-------RNYPTNTYKTLELE----------IA 344

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720364114 1493 EEVVKLeKDPDLERSTEALRRELDQEKnrVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIR--VEKDPVLE 1563
Cdd:NF033838   345 ESDVKV-KEAELELVKEEAKEPRNEEK--IKQAKAKVESKKAEATRLEKIKTDRKKAEEEAKRkaAEEDKVKE 414
RGS_LARG cd08754
Regulator of G protein signaling (RGS) domain found in the leukemia-associated Rho guanine ...
 609-744 6.31e-03

Regulator of G protein signaling (RGS) domain found in the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF) protein (LARG); The RGS domain is an essential part of the leukemia-associated RhoGEF protein (LARG), a member of the RhoGEF (Rho guanine nucleotide exchange factor) subfamily of the RGS protein family. The RhoGEFs are peripheral membrane proteins that regulate essential cellular processes, including cell shape, cell migration, cell cycle progression of cells, and gene transcription by linking signals from heterotrimeric G-alpha12/13 protein-coupled receptors to Rho GTPase activation, leading to various cellular responses, such as actin reorganization and gene expression. The RhoGEF subfamily includes p115RhoGEF, LARG, PDZ-RhoGEF, and its rat specific splice variant GTRAP48. The RGS domain of RhoGEFs has very little sequence similarity with the canonical RGS domain of the RGS proteins and is often refered to as RH (RGS Homology) domain. In addition to being a G-alpha13 effector, the LARG protein also functions as a GTPase-activating protein (GAP) for G-alpha13. RGS proteins play critical regulatory role as GTPase activating proteins (GAPs) of the heterotrimeric G-protein G-alpha-subunits. RGS proteins play critical regulatory role as GTPase activating proteins (GAPs) of the heterotrimeric G-protein G-alpha-subunits. RGS proteins regulate many aspects of embryonic development such as glial differentiation, embryonic axis formation, skeletal and muscle development, cell migration during early embryogenesis, as well as apoptosis, cell proliferation, and modulation of cardiac development.


Pssm-ID: 188708  Cd Length: 222  Bit Score: 40.36  E-value: 6.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  609 GAEKEAAQQECEAFLSTKPTGSAALQLPVVLNSVKNRYNDVQSLCHLYGEKAKaalglEKQIQEADRVIQGF-----EAA 683
Cdd:cd08754     11 PTESEQINGQCSCFQNIELLKSRPAHLAVFLHHVVSQFDPAALLCYLYADLYK-----QTNSKETRRVFLEFnqfflDRA 85

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720364114  684 LALEGPVPEgsgalqERVSELQRQRKELLQQQacvlgLHRQLKAT--EHACSALQNNFQEFCQ 744
Cdd:cd08754     86 ANLKVPVPD------EVSLDLEKRRPELIPEE-----LHRHYIQTmqERVSPEVQRNLEDFRQ 137
 
Name Accession Description Interval E-value
SH3_10 pfam17902
SH3 domain; This entry represents an SH3 domain.
 433-497 8.99e-25

SH3 domain; This entry represents an SH3 domain.


Pssm-ID: 407754  Cd Length: 65  Bit Score: 98.87  E-value: 8.99e-25
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720364114  433 PLPQRRNPSKQPLHVDSICDWDSGEVQLLRGERYTLKDNADPYTWLVQGPGGETKSAPAACLCIP 497
Cdd:pfam17902    1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 880-1675 9.77e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.15  E-value: 9.77e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  880 ESIQAQEKnLAKAYTEVaaaeQQQLRQLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVA 959
Cdd:TIGR02168  203 KSLERQAE-KAERYKEL----KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  960 EVQRDLEEQRQRLLQLRTQQpvARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKT 1039
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1040 MQPHLLTKEVTQIERDPG---LDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDL 1116
Cdd:TIGR02168  356 LEAELEELEAELEELESRleeLEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1117 EMVKAA-QTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEpkvivkevkkveqdpgllKEASRLRSLLEeeknn 1195
Cdd:TIGR02168  436 KELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAE------------------RELAQLQARLD----- 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1196 nvALARELQELQEKYR----VVEKQKPKVQLQERVSEIFQVLPETEQEIRR-LRAQLQE-TGSKKSGVEQEVEKLLP--- 1266
Cdd:TIGR02168  493 --SLERLQENLEGFSEgvkaLLKNQSGLSGILGVLSELISVDEGYEAAIEAaLGGRLQAvVVENLNAAKKAIAFLKQnel 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1267 ------ELEVLRAQKPVVEYKEVTQEV-------VRHEKNPEVLRE-----------IDRLKAQLNELVNTNGRsqEQLI 1322
Cdd:TIGR02168  571 grvtflPLDSIKGTEIQGNDREILKNIegflgvaKDLVKFDPKLRKalsyllggvlvVDDLDNALELAKKLRPG--YRIV 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1323 RLQGERDEWK----RERSKVETKMVSKevvrhekdpvlEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEE 1398
Cdd:TIGR02168  649 TLDGDLVRPGgvitGGSAKTNSSILER-----------RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1399 QIVVQEVVVTQKDpkLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLsfEEDRSKKLAAERELRQLTLKIQE 1478
Cdd:TIGR02168  718 RKELEELSRQISA--LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL--EEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1479 LEKRPPALQEKIimeevvklekdpdlerstEALRRELDQEKNRVTELHRECQGLQVQVDLLQK--TKSQEKTIYKEVIRV 1556
Cdd:TIGR02168  794 LKEELKALREAL------------------DELRAELTLLNEEAANLRERLESLERRIAATERrlEDLEEQIEELSEDIE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1557 EKDPVLEGERARVWEI---LNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELE 1633
Cdd:TIGR02168  856 SLAAEIEELEELIEELeseLEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1720364114 1634 QQKQQKARQLQEEGRL-------LSQKTESERQKAAQRsqaVTQLEAAI 1675
Cdd:TIGR02168  936 VRIDNLQERLSEEYSLtleeaeaLENKIEDDEEEARRR---LKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1126-1674 5.09e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.70  E-value: 5.09e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1126 RLQIEEDAARRKGAKETVAKIQARIKDLEQAISSvepkvivkevkkveqdpgLLKEASRLRSLLEEEKNNNVALARELQE 1205
Cdd:COG1196    224 ELEAELLLLKLRELEAELEELEAELEELEAELEE------------------LEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1206 LQEKYRVVEKQKPKVQ-----LQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVEY 1280
Cdd:COG1196    286 AQAEEYELLAELARLEqdiarLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1281 KEVTQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDPVLEKEA 1360
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1361 ER-------------LRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRsLDE 1427
Cdd:COG1196    446 EAaeeeaeleeeeeaLLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG-LAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1428 EVGRRRQLELEVRQ---------LGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKL 1498
Cdd:COG1196    525 AVAVLIGVEAAYEAaleaalaaaLQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1499 EKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIykevirVEKDPVLEGERARvwEILNRERA 1578
Cdd:COG1196    605 ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG------GSAGGSLTGGSRR--ELLAALLE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1579 ARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESER 1658
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756

                          570
                   ....*....|....*.
gi 1720364114 1659 QKAAQRSQAVTQLEAA 1674
Cdd:COG1196    757 PEPPDLEELERELERL 772
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 843-1568 1.46e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 1.46e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  843 LQEALQDYELQADTYRCSLEPALAVSAPKRLRVISLQESIQAQEKNLAKAYTEVAAAEQQqLRQLEFAKKMLRK--KELD 920
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ-KQILRERLANLERqlEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  921 EDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQqpvARLEEKEVVEFYRDPQLES 1000
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ---LETLRSKVAQLELQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1001 N-LSQAASRVEEEGKRRARLQAELEAVAQKVVHLE--------GKRKTMQPHLLTKEVTQIERDPGLDSQVTQLHSEMQR 1071
Cdd:TIGR02168  400 NeIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqaelEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1072 LRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDL--EMVKAAQTLRLQIEEDAARRKGA-----KETVA 1144
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlsELISVDEGYEAAIEAALGGRLQAvvvenLNAAK 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1145 KIQARIKDLEQAISSVEP-------KVIVKEVKKVEQDPGLLKEASRLRSLLEEEKN------------NNVALARELQ- 1204
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLPldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvDDLDNALELAk 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1205 ELQEKYRVVEKQKPKV-----QLQERVSEIFQVLpETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVE 1279
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVrpggvITGGSAKTNSSIL-ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR 718

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1280 YKEVTQEvvrheknpevlREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEkdpvLEKE 1359
Cdd:TIGR02168  719 KELEELS-----------RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE----AEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1360 AERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRpeeqivvqeVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLELEV 1439
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTLLNEEA---------ANLRERLESLERRIAATERRLEDLEEQIEELSEDI 854

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1440 RQLGARVEEEEARLSFEEDRSKKLAAERElrQLTLKIQELEKRPPALQEKIimeevvklekdPDLERSTEALRRELDQEK 1519
Cdd:TIGR02168  855 ESLAAEIEELEELIEELESELEALLNERA--SLEEALALLRSELEELSEEL-----------RELESKRSELRRELEELR 921

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1520 NRVTELHRECQGLQVQVD-LLQKTKSQEKTIYKEVIRVEKDPVLEGERAR 1568
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDnLQERLSEEYSLTLEEAEALENKIEDDEEEAR 971
PTZ00121 PTZ00121
MAEBL; Provisional
 1117-1730 1.07e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 90.59  E-value: 1.07e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1117 EMVKAAQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNN 1196
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1197 VALARELQELQEKyRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKP 1276
Cdd:PTZ00121  1289 KKKADEAKKAEEK-KKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1277 VVEYK--EVTQEVVRHEKNPEVLREIDRLKAQLNElvntNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDP 1354
Cdd:PTZ00121  1368 AAEKKkeEAKKKADAAKKKAEEKKKADEAKKKAEE----DKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEA 1443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1355 VLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDP-KLREEHSRLSRSLDEEVGRRR 1433
Cdd:PTZ00121  1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEaKKAAEAKKKADEAKKAEEAKK 1523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1434 QLELEVRQLGARVEE----EEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQ--------EKIIMEEVVKLEKD 1501
Cdd:PTZ00121  1524 ADEAKKAEEAKKADEakkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRkaeeakkaEEARIEEVMKLYEE 1603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1502 PDLERSTEAlrRELDQEKNRVTELHREcQGLQVQVDLLQKTKSQEKTIYKEV--------IRVEKDPVLEGERARVWEIL 1573
Cdd:PTZ00121  1604 EKKMKAEEA--KKAEEAKIKAEELKKA-EEEKKKVEQLKKKEAEEKKKAEELkkaeeenkIKAAEEAKKAEEDKKKAEEA 1680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1574 NRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKqQKARQLQEEgrllsqk 1653
Cdd:PTZ00121  1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDK-KKAEEAKKD------- 1752

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720364114 1654 tESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLStkicilepETGNDMSPY 1730
Cdd:PTZ00121  1753 -EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANII--------EGGKEGNLV 1820
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 884-1525 6.11e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 87.68  E-value: 6.11e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  884 AQEKNLAKAYTEVAAAEQQ---QLRQLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAE 960
Cdd:COG1196    206 ERQAEKAERYRELKEELKEleaELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  961 VQRDLEEQRQRLLQLRTQQPVARLEEKEVVEfyRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEgkrktm 1040
Cdd:COG1196    286 AQAEEYELLAELARLEQDIARLEERRRELEE--RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE------ 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1041 qphlltkevtqierdpgldsqvTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEmnvkekvvvkevvkvekdlemvK 1120
Cdd:COG1196    358 ----------------------AELAEAEEALLEAEAELAEAEEELEELAEELLEAL----------------------R 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1121 AAQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVALA 1200
Cdd:COG1196    394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1201 RELQELQEKYRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQ--LQETGSKKSGVEQEVEKLLPELEVLRAQKPVV 1278
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrgLAGAVAVLIGVEAAYEAALEAALAAALQNIVV 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1279 EYKEVTQEVVRHEKNpevlREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRH--EKDPVL 1356
Cdd:COG1196    554 EDDEVAAAAIEYLKA----AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTllGRTLVA 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1357 EKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRpeeqivvqevvvtqkdpKLREEHSRLSRSLDEEVGRRRQLE 1436
Cdd:COG1196    630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR-----------------ELLAALLEAEAELEELAERLAEEE 692

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1437 LEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERstEALRRELD 1516
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL--EELERELE 770


                   ....*....
gi 1720364114 1517 QEKNRVTEL 1525
Cdd:COG1196    771 RLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 770-1656 3.99e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 81.65  E-value: 3.99e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  770 REKIVQDASLTYQQLRNSRDNLSSWLEQLPHHRVQPS--------DGPSQISYKLQAQKRLIQEILGreqdqatVSRLTR 841
Cdd:TIGR02169   98 RLKVTDDGKYSYYYLNGQRVRLSEIHDFLAAAGIYPEgynvvlqgDVTDFISMSPVERRKIIDEIAG-------VAEFDR 170

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  842 DLQEALQDYElqadTYRCSLEPALAVSAPKRLRVISLQEsiqaqEKNLAKAYTEVaaaeQQQLRQLEFAKKMLRKKELDE 921
Cdd:TIGR02169  171 KKEKALEELE----EVEENIERLDLIIDEKRQQLERLRR-----EREKAERYQAL----LKEKREYEGYELLKEKEALER 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  922 DIQAIHSARQGsgspahaRTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQPVARLEEKEVVEFYRDpQLESN 1001
Cdd:TIGR02169  238 QKEAIERQLAS-------LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA-SLERS 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1002 LSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHL--LTKEVTQI-ERDPGLDSQVTQLHSEMQRLRGENGV 1078
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRdkLTEEYAELkEELEDLRAELEEVDKEFAETRDELKD 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1079 LTARLEELKDEL--LALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQT--------LRLQIEEDAARRKGAKETVAKIQA 1148
Cdd:TIGR02169  390 YREKLEKLKREIneLKRELDRLQEELQRLSEELADLNAAIAGIEAKINeleeekedKALEIKKQEWKLEQLAADLSKYEQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1149 RIKDLEQAISSVEPKVIVKEVKKVEQDP--GLLKEASRLRSLLEEEKNNNV----ALARELQELQEKYR----------- 1211
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAqaRASEERVRGGRAVEEVLKASIqgvhGTVAQLGSVGERYAtaievaagnrl 549

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1212 ---VVEKQKPKVQ----LQERVSEIFQVLPeteqeIRRLRAQLQETG-SKKSGVeqeVEKLLPELEVLRAQKPVVEYKEV 1283
Cdd:TIGR02169  550 nnvVVEDDAVAKEaielLKRRKAGRATFLP-----LNKMRDERRDLSiLSEDGV---IGFAVDLVEFDPKYEPAFKYVFG 621

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1284 TQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETkmvskevVRHEKDPvLEKEAERL 1363
Cdd:TIGR02169  622 DTLVVEDIEAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQR-------LRERLEG-LKRELSSL 693

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1364 RQEVREAVQRRRATEDAVYELQNKLLLLERRRPEeqivvqevvvtqkdpkLREEHSRLsrsldeevgRRRQLELEVRQLG 1443
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSDASRKIGEIEKEIEQ----------------LEQEEEKL---------KERLEELEEDLSS 748

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1444 ARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDpdlERSTEALRRELDQEKNRVT 1523
Cdd:TIGR02169  749 LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEE---VSRIEARLREIEQKLNRLT 825

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1524 E----LHRECQGLQVQVDLLqktKSQEKTIYKEVirvekdPVLEGERARVWEILNRERAARKGREEDVRSLQERIDRAEA 1599
Cdd:TIGR02169  826 LekeyLEKEIQELQEQRIDL---KEQIKSIEKEI------ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720364114 1600 LRRswsreeaELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTES 1656
Cdd:TIGR02169  897 QLR-------ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI 946
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1356-1706 7.84e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.75  E-value: 7.84e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1356 LEKEAERLRQEVREAVQRRRATEDAVyELQNKLLLLERRRpeeqivvqevvvtqkdpkLREEHSRLSRSLDEEVGRRRQL 1435
Cdd:COG1196    198 LERQLEPLERQAEKAERYRELKEELK-ELEAELLLLKLRE------------------LEAELEELEAELEELEAELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1436 ELEVRQLGArvEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKrppalqekiimeevvklEKDPDLERStEALRREL 1515
Cdd:COG1196    259 EAELAELEA--ELEELRLELEELELELEEAQAEEYELLAELARLEQ-----------------DIARLEERR-RELEERL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1516 DQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEvirvekdpvLEGERARVWEILNRERAARKGREEDVRSLQERID 1595
Cdd:COG1196    319 EELEEELAELEEELEELEEELEELEEELEEAEEELEE---------AEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1596 RAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVTQLEAAI 1675
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1720364114 1676 LQEKDKIYEKERTLRDLHTKVSREELNQETQ 1706
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAE 500
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1059-1704 1.04e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 80.50  E-value: 1.04e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1059 DSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKG 1138
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1139 AKETVAKIQARIKDLEQAISSVEPKvivkevkkveqdpgLLKEASRLRSLLEEEKNnnvALARELQELQEKYR-----VV 1213
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQL--------------LEELNKKIKDLGEEEQL---RVKEKIGELEAEIAslersIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1214 EKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQkpvVEYKEVTQEVVRhEKN 1293
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE---LEEVDKEFAETR-DEL 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1294 PEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDpvleKEAERLRQEVREAVQR 1373
Cdd:TIGR02169  388 KDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA----LEIKKQEWKLEQLAAD 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1374 RRATEDAVYELQNKLLLLERRRpeeqivvqevvvTQKDPKLREEHSRLSRSLDEEVGRRRQLEL----------EVRQLG 1443
Cdd:TIGR02169  464 LSKYEQELYDLKEEYDRVEKEL------------SKLQRELAEAEAQARASEERVRGGRAVEEVlkasiqgvhgTVAQLG 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1444 aRVEEEEA---------RLSF---EED----RSKKLAAERELRQLTL----KIQELEKRPPALQEKIIMEEVVKL-EKDP 1502
Cdd:TIGR02169  532 -SVGERYAtaievaagnRLNNvvvEDDavakEAIELLKRRKAGRATFlplnKMRDERRDLSILSEDGVIGFAVDLvEFDP 610

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1503 DLE-------------RSTEALRRELDQ---------------------------------EKNRVTELHRECQGLQVQV 1536
Cdd:TIGR02169  611 KYEpafkyvfgdtlvvEDIEAARRLMGKyrmvtlegelfeksgamtggsraprggilfsrsEPAELQRLRERLEGLKREL 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1537 D-LLQKTKSQEKTIYKEVIRVEKDPVLEGERARVWEILNRERAARKGREEDVRSLQERIDRA-EALRRSWSREEAELQRA 1614
Cdd:TIGR02169  691 SsLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEiENVKSELKELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1615 RDQASQdcgrLQRQLRELE--------QQKQQKARQLQE-----EGRL--LSQKTESERQKAAQRSQAVTQLEAAILQEK 1679
Cdd:TIGR02169  771 EEDLHK----LEEALNDLEarlshsriPEIQAELSKLEEevsriEARLreIEQKLNRLTLEKEYLEKEIQELQEQRIDLK 846

                          730       740
                   ....*....|....*....|....*
gi 1720364114 1680 DKIYEKERTLRDLHTKVsrEELNQE 1704
Cdd:TIGR02169  847 EQIKSIEKEIENLNGKK--EELEEE 869
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
951-1525 5.35e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 74.69  E-value: 5.35e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  951 LEEERKRVAE----VQRDLEEQRQRLLQLRTQqpVARLEEKEVVEfyRDPQLESNLSQAASRVE--EEGKRRAR-----L 1019
Cdd:PRK02224   164 LEEYRERASDarlgVERVLSDQRGSLDQLKAQ--IEEKEEKDLHE--RLNGLESELAELDEEIEryEEQREQARetrdeA 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1020 QAELEAVAQKVVHLEGKRKTMQPHLLTKEVTQIERDpGLDSQVTQLHSEMQRLRGENGVLTAR--LEELKDELLALEQKE 1097
Cdd:PRK02224   240 DEVLEEHEERREELETLEAEIEDLRETIAETERERE-ELAEEVRDLRERLEELEEERDDLLAEagLDDADAEAVEARREE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1098 MNVKEKVVVKEVVKVEKDLEMVKA---------------AQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEP 1162
Cdd:PRK02224   319 LEDRDEELRDRLEECRVAAQAHNEeaeslredaddleerAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRE 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1163 KVIVKevkkveqdPGLLKEASRLRSLLEEEKNNnvaLARELQELQEKYRVVEkqkpkvqlqERVSEIFQVL-----PETE 1237
Cdd:PRK02224   399 RFGDA--------PVDLGNAEDFLEELREERDE---LREREAELEATLRTAR---------ERVEEAEALLeagkcPECG 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1238 QEIRRlrAQLQETGSKKsgvEQEVEKLLPELEVLRAQKpvveyKEVTQEVVRHEKNPEVLREIDRLKAQ---LNELVNTn 1314
Cdd:PRK02224   459 QPVEG--SPHVETIEED---RERVEELEAELEDLEEEV-----EEVEERLERAEDLVEAEDRIERLEERredLEELIAE- 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1315 grsQEQLIRLQGERDEWKRER-SKVETKMVSKEVVRHEKdpvlEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLER 1393
Cdd:PRK02224   528 ---RRETIEEKRERAEELRERaAELEAEAEEKREAAAEA----EEEAEEAREEVAELNSKLAELKERIESLERIRTLLAA 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1394 RRPEEQIVVqevvvtqkdpKLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEearlSFEEDRSKKLAAERELRQLT 1473
Cdd:PRK02224   601 IADAEDEIE----------RLREKREALAELNDERRERLAEKRERKRELEAEFDEA----RIEEAREDKERAEEYLEQVE 666

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1720364114 1474 LKIQELEKRPPALQEKIIMEEvvklekdPDLERsTEALRRELDQEKNRVTEL 1525
Cdd:PRK02224   667 EKLDELREERDDLQAEIGAVE-------NELEE-LEELRERREALENRVEAL 710
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1178-1714 2.01e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 2.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1178 LLKEASRLRSLLEEEKNNNVALARELQELQEKyrVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGV 1257
Cdd:TIGR02168  237 LREELEELQEELKEAEEELEELTAELQELEEK--LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1258 EQEVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEKNPEVLR---EIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRE 1334
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESleaELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1335 RSKvetkmVSKEVVRHEKD-PVLEKEAERLRQEVREavQRRRATEDAVYELQNKLLLLERRRpeeqivvqevvvtqkdPK 1413
Cdd:TIGR02168  395 IAS-----LNNEIERLEARlERLEDRRERLQQEIEE--LLKKLEEAELKELQAELEELEEEL----------------EE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1414 LREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARL-SFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIM 1492
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLdSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1493 EEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRE--------CQGLQVQVDLLQKTKSQEKTIYKEVIRVEKDPVLEG 1564
Cdd:TIGR02168  532 DEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQnelgrvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1565 ERARVW-----------------------------------EILNRERAARKGREEDVRSLQER---IDRAEALRRSWSR 1606
Cdd:TIGR02168  612 PKLRKAlsyllggvlvvddldnalelakklrpgyrivtldgDLVRPGGVITGGSAKTNSSILERrreIEELEEKIEELEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1607 EEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQL---QEEGRLLSQKTESERQKAAQRSQAVTQLEAAILQEKDKIY 1683
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQIsalRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1720364114 1684 EKERTLRDLHTKvsREELNQETQTRETNLST 1714
Cdd:TIGR02168  772 EAEEELAEAEAE--IEELEAQIEQLKEELKA 800
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 510-1339 3.01e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.40  E-value: 3.01e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  510 LATELQTLKQKLSTEKNRLKAAAVEHLQpgqqapagsapADPQGQTLLSQMTQLDGDLGQIERQVLSWARSPLSQSSSLK 589
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEE-----------LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEIS 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  590 DLEGRIhscEGTAQRLQSLGAEKEAAQQECEAFLSTKPTGSAAL-QLPVVLNSVKNRYNDVQSLchlYGEKAKAALGLEK 668
Cdd:TIGR02168  299 RLEQQK---QILRERLANLERQLEELEAQLEELESKLDELAEELaELEEKLEELKEELESLEAE---LEELEAELEELES 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  669 QIQEADRVIQGFEAALA-LEGPVPEGSGALQERVSELQRQRKELLQQQACVLGLHRQLKatEHACSALQNNFQEFCQDLP 747
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAqLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  748 RQQRQVRALTDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDNLSSWLEQLphhrvqpsDGPSQISYKLQAQKRLIQEIL 827
Cdd:TIGR02168  451 ELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL--------EGFSEGVKALLKNQSGLSGIL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  828 GREQDQATV-----------------SRLTRDLQEALQDYEL--QADTYRCSLEPALAVSAPK----RLRVISLQESIQA 884
Cdd:TIGR02168  523 GVLSELISVdegyeaaieaalggrlqAVVVENLNAAKKAIAFlkQNELGRVTFLPLDSIKGTEiqgnDREILKNIEGFLG 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  885 QEKNLAKAYTEVAAAEQQQLRQ------LEFAKKMLRKKELDEDI-----QAIHsaRQGSGSPAHARTAESEVLKTQ-LE 952
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYLLGGvlvvddLDNALELAKKLRPGYRIvtldgDLVR--PGGVITGGSAKTNSSILERRReIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  953 EERKRVAEVQRDLEEQRQRLLQLRTQQPvarleekevvefyrdpQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVH 1032
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELE----------------ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1033 LEgkrktmqphlltkevtqierdpgldSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVvkevvkv 1112
Cdd:TIGR02168  745 LE-------------------------ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE------- 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1113 ekdlEMVKAAQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEqdpgLLKEASRLRSLLEEE 1192
Cdd:TIGR02168  793 ----QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE----LSEDIESLAAEIEEL 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1193 KNNNVALARELQELQEKYRVVEKQKpkVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLR 1272
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEAL--ALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720364114 1273 AQKPV---VEYKEVTQEVVRHEKNPEVLR-EIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVE 1339
Cdd:TIGR02168  943 ERLSEeysLTLEEAEALENKIEDDEEEARrRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLT 1013
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 942-1700 2.01e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.71  E-value: 2.01e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  942 AESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQPVAR-----LEEKEVVEFY------------------RDPQL 998
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAEryqalLKEKREYEGYellkekealerqkeaierQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  999 ESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHL-EGKRKTMQPHLLTKEVtQIERdpgLDSQVTQLHSEMQRLRGENG 1077
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEA-EIAS---LERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1078 VLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMvkaaQTLRLQIEEDAARrkgAKETVAKIQARIKDLEQAI 1157
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEL----EDLRAELEEVDKE---FAETRDELKDYREKLEKLK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1158 SSVEPKVIVKEVkkveqdpgLLKEASRLRSLLEEEKNNNVALARELQELQEkyRVVEKQKPKVQLQERVSEIFQVLPETE 1237
Cdd:TIGR02169  399 REINELKRELDR--------LQEELQRLSEELADLNAAIAGIEAKINELEE--EKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1238 QEIRRLRAQLQEtgskksgVEQEVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEKNPEV------LREIDRLKAQ----- 1306
Cdd:TIGR02169  469 QELYDLKEEYDR-------VEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIqgvhgtVAQLGSVGERyatai 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1307 -------LNELVNTNGRSQEQLIRLQGER----------DEWKRERSKV----ETKMVSKEVVRHEKDPVLEK------- 1358
Cdd:TIGR02169  542 evaagnrLNNVVVEDDAVAKEAIELLKRRkagratflplNKMRDERRDLsilsEDGVIGFAVDLVEFDPKYEPafkyvfg 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1359 ---------EAERLRQEVR------EAVQR--------RRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLR 1415
Cdd:TIGR02169  622 dtlvvedieAARRLMGKYRmvtlegELFEKsgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1416 EEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLsfEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKI--IME 1493
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERL--EELEEDLSSLEQEIENVKSELKELEARIEELEEDLhkLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1494 EVVKLEKDPDLERStealrRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIrvekdpvlEGERARVWEIL 1573
Cdd:TIGR02169  780 ALNDLEARLSHSRI-----PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI--------QELQEQRIDLK 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1574 NRERAARKGREE---DVRSLQERIDRAEALRRSWSREEAELQRARDqasqdcgRLQRQLRELEQQKQQKARQLQEEGRLL 1650
Cdd:TIGR02169  847 EQIKSIEKEIENlngKKEELEEELEELEAALRDLESRLGDLKKERD-------ELEAQLRELERKIEELEAQIEKKRKRL 919

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1651 SQKTEserqKAAQRSQAVTQLEAAILQEKDkIYEKERTLRDLHTKVSREE 1700
Cdd:TIGR02169  920 SELKA----KLEALEEELSEIEDPKGEDEE-IPEEELSLEDVQAELQRVE 964
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1189-1692 2.09e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 69.32  E-value: 2.09e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1189 LEEEKNNNVALARELQELQEKYRVVEKQKPkvQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVE---QEVEKLL 1265
Cdd:PRK03918   160 YENAYKNLGEVIKEIKRRIERLEKFIKRTE--NIEELIKEKEKELEEVLREINEISSELPELREELEKLEkevKELEELK 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1266 PELEVLRAQKPVVEYKEVTQEvvrhEKNPEVLREIDRLKAQLNELVNTNGRSQE------QLIRLQGERDEWKRERSKVE 1339
Cdd:PRK03918   238 EEIEELEKELESLEGSKRKLE----EKIRELEERIEELKKEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1340 TKMVSKEVVRHEKDPVLeKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPeeqivVQEVVVTQKDPKLREEHS 1419
Cdd:PRK03918   314 KRLSRLEEEINGIEERI-KELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA-----KKEELERLKKRLTGLTPE 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1420 RLSRSLDEEVGRRRQLELEVRQLGARV-----EEEEARLSFEEDRSKK---------LAAERE---LRQLTLKIQELEKR 1482
Cdd:PRK03918   388 KLEKELEELEKAKEEIEEEISKITARIgelkkEIKELKKAIEELKKAKgkcpvcgreLTEEHRkelLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1483 PPALQEKI--IMEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHR-ECQGLQVQVDLLQKTKSQEKTIYKEVIRVEKD 1559
Cdd:PRK03918   468 LKEIEEKErkLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKE 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1560 ----PVLEGERARVWEIL--------NRERAARKGREEDVRSLQERIDRAEALRRSW----------SREEAELQRARDQ 1617
Cdd:PRK03918   548 leklEELKKKLAELEKKLdeleeelaELLKELEELGFESVEELEERLKELEPFYNEYlelkdaekelEREEKELKKLEEE 627

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720364114 1618 ASQDCGRLQRQLRELEQQKqqkaRQLQEEGRLLSQKT-ESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDL 1692
Cdd:PRK03918   628 LDKAFEELAETEKRLEELR----KELEELEKKYSEEEyEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 503-1275 2.59e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 2.59e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  503 AVAKASRLATELQTLKQKLSTEKNRLKAAAVEHLQPGQQAPAGSAPADPQGQTLLSQMTQLDGDLGQIERQvlswarspl 582
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK--------- 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  583 sqsssLKDLEGRIHSCEGTAQRLQSLGAEKEAAQQECEAFLSTKPTGSAALQLPVVLNSVKNRYNDVQsLCHLYGEKAK- 661
Cdd:TIGR02168  346 -----LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR-LERLEDRRERl 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  662 ----AALGLEKQIQEADRVIQGFEAALALEGPVPEGSGALQERVSELQRQRKELLQQQACVLGLHRQLKATEHACSALQN 737
Cdd:TIGR02168  420 qqeiEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  738 NFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREK------IVQDASLTYQQLRNSRDNLSSW--LEQLPHHRVQPSDGP 809
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyeaaieAALGGRLQAVVVENLNAAKKAIafLKQNELGRVTFLPLD 579

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  810 SQISYKLQAQKRLIQEILGREQDQA-----TVSRLTRDLQEALQDYeLQADTYRCSLEpaLAVSAPKRLRVISLQESIqa 884
Cdd:TIGR02168  580 SIKGTEIQGNDREILKNIEGFLGVAkdlvkFDPKLRKALSYLLGGV-LVVDDLDNALE--LAKKLRPGYRIVTLDGDL-- 654

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  885 qeknLAKAYTEVAAAEQQQLRQLEFAKKMlrkKELDEDIQAIHSArqgsgspAHARTAESEVLKTQLEEERKRVAEVQRD 964
Cdd:TIGR02168  655 ----VRPGGVITGGSAKTNSSILERRREI---EELEEKIEELEEK-------IAELEKALAELRKELEELEEELEQLRKE 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  965 LEEQRQRLLQLRTQqpVARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQphl 1044
Cdd:TIGR02168  721 LEELSRQISALRKD--LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK--- 795

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1045 ltKEVTQIERdpgldsQVTQLHSEMQRLRGENGVLTARLEELKDElLALEQKEMNvkekvvvkevvkvekdlEMVKAAQT 1124
Cdd:TIGR02168  796 --EELKALRE------ALDELRAELTLLNEEAANLRERLESLERR-IAATERRLE-----------------DLEEQIEE 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1125 LRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLL---KEASRLRSLLEEEKNNNVALAR 1201
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELReleSKRSELRRELEELREKLAQLEL 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1202 ELQELQEKYRvvekqkpkvQLQERVSEIFQVLPE---------------TEQEIRRLRAQLQETGSKKSGVEQEVEKLLP 1266
Cdd:TIGR02168  930 RLEGLEVRID---------NLQERLSEEYSLTLEeaealenkieddeeeARRRLKRLENKIKELGPVNLAAIEEYEELKE 1000


                   ....*....
gi 1720364114 1267 ELEVLRAQK 1275
Cdd:TIGR02168 1001 RYDFLTAQK 1009
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 587-1369 3.29e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 3.29e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  587 SLKDLEGRIHSCEGTAQRLQSLGAEKEAAQQECEAFLStkptgsaalQLPVVLNSVKNRYNDVQslcHLYGEKAKAALGL 666
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLE---------ELRLEVSELEEEIEELQ---KELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  667 EKQIQEADRVIQGFEAALAlegpvpegsgALQERVSELQRQRKELLQQqacvlglhrqLKATEHACSALQNNFQEFCQDL 746
Cdd:TIGR02168  301 EQQKQILRERLANLERQLE----------ELEAQLEELESKLDELAEE----------LAELEEKLEELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  747 PRQQRQVRALTDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDNLSSWLEQLPHHRVQPSDGPSQISYKLQ-AQKRLIQE 825
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeAELKELQA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  826 ILGREQDQATvsrltrDLQEALQDYELQADTYRCSLEPALAVSAPKRLRVISLQ---ESIQAQEKNLAKAYTEVAAAEQQ 902
Cdd:TIGR02168  441 ELEELEEELE------ELQEELERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEGVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  903 QLR----------QLEFAKKMLRKKE--LDEDIQAIHSARQGSGSPAHARTAESEVLK-TQLEEERKRVAEVQRDLEEQR 969
Cdd:TIGR02168  515 QSGlsgilgvlseLISVDEGYEAAIEaaLGGRLQAVVVENLNAAKKAIAFLKQNELGRvTFLPLDSIKGTEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  970 QrllqlrtQQPVARLEEKEVVEFyrDPQLESNLSQ--AASRVEEEGKRRARLQAELEAvAQKVVHLEGkrktmqpHLLTK 1047
Cdd:TIGR02168  595 K-------NIEGFLGVAKDLVKF--DPKLRKALSYllGGVLVVDDLDNALELAKKLRP-GYRIVTLDG-------DLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1048 EVTQIERDPGLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQK--EMNVKEKVVVKEVVKVEKDL-EMVKAAQT 1124
Cdd:TIGR02168  658 GGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEleELEEELEQLRKELEELSRQIsALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1125 LRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDP---GLLKEASRLRSLLEEEKNNNVALAR 1201
Cdd:TIGR02168  738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAqieQLKEELKALREALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1202 ELQELQEKYRVVEKQkpKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVEYK 1281
Cdd:TIGR02168  818 EAANLRERLESLERR--IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1282 EVTQEVVRHEKNpevlREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWK---RERSKVETKMVSKEVVRHEKDP-VLE 1357
Cdd:TIGR02168  896 LEELSEELRELE----SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQerlSEEYSLTLEEAEALENKIEDDEeEAR 971

                          810
                   ....*....|..
gi 1720364114 1358 KEAERLRQEVRE 1369
Cdd:TIGR02168  972 RRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1185-1574 3.70e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 3.70e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1185 LRSLLEE------------EKNNNVALARE-LQELQEKYRVVEKQKPKVQLQERVSEIFQ----------------VLPE 1235
Cdd:TIGR02168  157 RRAIFEEaagiskykerrkETERKLERTREnLDRLEDILNELERQLKSLERQAEKAERYKelkaelrelelallvlRLEE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1236 TEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVEYKEVTQEvvrhEKNPEVLREIDRLKAQLNELVNTNG 1315
Cdd:TIGR02168  237 LREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ----KELYALANEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1316 RSQEQLIRLQGERDEWKRERSKVETKMVSKEvvrhEKDPVLEKEAERLRQEVREAVQRRRATEDAVYELQNKllllerrr 1395
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELE----EKLEELKEELESLEAELEELEAELEELESRLEELEEQ-------- 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1396 peeqivvqevvvtqkdpklreehsrlsrsLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLK 1475
Cdd:TIGR02168  381 -----------------------------LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE 431

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1476 IQELEKRPPALQEKIIMEEVVKlEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIR 1555
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQ-EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKA 510

                          410       420
                   ....*....|....*....|
gi 1720364114 1556 VEKD-PVLEGERARVWEILN 1574
Cdd:TIGR02168  511 LLKNqSGLSGILGVLSELIS 530
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1047-1614 5.09e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.17  E-value: 5.09e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1047 KEVTQIERdpgldsQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEmnvkekvvvkevvkvEKDLEMVKAAQTLR 1126
Cdd:PRK03918   200 KELEEVLR------EINEISSELPELREELEKLEKEVKELEELKEEIEELE---------------KELESLEGSKRKLE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1127 LQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDP--GLLKEASRLRSLLEEeknnnvaLARELQ 1204
Cdd:PRK03918   259 EKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDElrEIEKRLSRLEEEING-------IEERIK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1205 ELQEKYRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGveQEVEKLLPELEVLRAQKPVV--EYKE 1282
Cdd:PRK03918   332 ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG--LTPEKLEKELEELEKAKEEIeeEISK 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1283 VTQEVVRHEKnpevlrEIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVR-HEKDPVLEKEAE 1361
Cdd:PRK03918   410 ITARIGELKK------EIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEiEEKERKLRKELR 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1362 RLRQEVREA--VQRRRATEDAVYELQNKLlllerrrpEEQIVVQEVVVTQKDPKLREEHSRLS---RSLDEEVGRRRQLE 1436
Cdd:PRK03918   484 ELEKVLKKEseLIKLKELAEQLKELEEKL--------KKYNLEELEKKAEEYEKLKEKLIKLKgeiKSLKKELEKLEELK 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1437 LEVRQLGARVEEEEARLSFEEDRSKKLAAErELRQLTLKIQELEKrppalqekiIMEEVVKLEKDP----DLERSTEALR 1512
Cdd:PRK03918   556 KKLAELEKKLDELEEELAELLKELEELGFE-SVEELEERLKELEP---------FYNEYLELKDAEkeleREEKELKKLE 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1513 RELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIRVEKDPVLEGERARVWEI-------------LNRERAA 1579
Cdd:PRK03918   626 EELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELekrreeikktlekLKEELEE 705

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1720364114 1580 RKGREEDVRSLQERIDRAEALRRSWSREEAELQRA 1614
Cdd:PRK03918   706 REKAKKELEKLEKALERVEELREKVKKYKALLKER 740
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 948-1645 9.75e-11

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 67.51  E-value: 9.75e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  948 KTQLEEERKRVAEVQRDLEEQRQRLL-QLRTQQPV-ARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAElea 1025
Cdd:pfam01576   21 QQKAESELKELEKKHQQLCEEKNALQeQLQAETELcAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNE--- 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1026 vaqkvvhlegkRKTMQPHLLTkevtqierdpgLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALE------QKEMN 1099
Cdd:pfam01576   98 -----------KKKMQQHIQD-----------LEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEdqnsklSKERK 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1100 VKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEedaarrkgakETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEqdpgLL 1179
Cdd:pfam01576  156 LLEERISEFTSNLAEEEEKAKSLSKLKNKHE----------AMISDLEERLKKEEKGRQELEKAKRKLEGESTD----LQ 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1180 KEASRLRSLLEEEKNNNVALARELQELQEkyRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQ 1259
Cdd:pfam01576  222 EQIAELQAQIAELRAQLAKKEEELQAALA--RLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGE 299

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1260 EVEKLLPELE----VLRAQKPVVEYKEvtQEVVRHEKNPEvlREIDRLKAQLNELvntNGRSQEQLIRLQGERDEWKRER 1335
Cdd:pfam01576  300 ELEALKTELEdtldTTAAQQELRSKRE--QEVTELKKALE--EETRSHEAQLQEM---RQKHTQALEELTEQLEQAKRNK 372

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1336 SKVETKMVSKEVVRHEkdpvLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQE----------- 1404
Cdd:pfam01576  373 ANLEKAKQALESENAE----LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKlqselesvssl 448

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1405 -VVVTQKDPKLREEHSRLSRSL-------DEEVGRRRQLELEVRQLgarvEEEEARL--SFEEDRSKKLAAERELRQLTL 1474
Cdd:pfam01576  449 lNEAEGKNIKLSKDVSSLESQLqdtqellQEETRQKLNLSTRLRQL----EDERNSLqeQLEEEEEAKRNVERQLSTLQA 524

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1475 KIQELEKRppaLQEKIIMEEVVKlEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVI 1554
Cdd:pfam01576  525 QLSDMKKK---LEEDAGTLEALE-EGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLE 600

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1555 RVEK--DPVLEGERARVWEILN-RERAARKGREEDVRSL---------QERIDRAEALRRSWSREEAELQRARDQASQDC 1622
Cdd:pfam01576  601 KKQKkfDQMLAEEKAISARYAEeRDRAEAEAREKETRALslaraleeaLEAKEELERTNKQLRAEMEDLVSSKDDVGKNV 680

                          730       740
                   ....*....|....*....|...
gi 1720364114 1623 GRLQRQLRELEQQKQQKARQLQE 1645
Cdd:pfam01576  681 HELERSKRALEQQVEEMKTQLEE 703
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1179-1699 3.63e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 65.32  E-value: 3.63e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1179 LKEASRLRSLLEEEknnnVALARELQELQEKYRVVEKQKPKVQLQERVSEIfQVLpetEQEIRRLRAQLQETGSKKSGVE 1258
Cdd:COG4913    244 LEDAREQIELLEPI----RELAERYAAARERLAELEYLRAALRLWFAQRRL-ELL---EAELEELRAELARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1259 QEVEKLLPELEVLRAQKPVVEYKEVTQevvrheknpeVLREIDRLKAQLNELVNTNGRSQEQLIRLQ----GERDEWKRE 1334
Cdd:COG4913    316 ARLDALREELDELEAQIRGNGGDRLEQ----------LEREIERLERELEERERRRARLEALLAALGlplpASAEEFAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1335 RSKVetkmvskevvrHEKDPVLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRR---PEEQIVVQEV-----V 1406
Cdd:COG4913    386 RAEA-----------AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsniPARLLALRDAlaealG 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1407 VTQKDPK-------LREEHSR-----------LSRSL--DEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAE 1466
Cdd:COG4913    455 LDEAELPfvgelieVRPEEERwrgaiervlggFALTLlvPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPD 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1467 RELRQLTLK-----------------------IQELEKRPPAL-QEKIIMEEVVKLEKDP------------DLERSTEA 1510
Cdd:COG4913    535 SLAGKLDFKphpfrawleaelgrrfdyvcvdsPEELRRHPRAItRAGQVKGNGTRHEKDDrrrirsryvlgfDNRAKLAA 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1511 LRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIyKEVIRVEKD-PVLEGERARvweiLNRERAARKGREEDVRS 1589
Cdd:COG4913    615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDvASAEREIAE----LEAELERLDASSDDLAA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1590 LQERIDRAEAlrrswsrEEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTES-------ERQKAA 1662
Cdd:COG4913    690 LEEQLEELEA-------ELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAlleerfaAALGDA 762

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1720364114 1663 QRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSRE 1699
Cdd:COG4913    763 VERELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1413-1709 5.88e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 5.88e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1413 KLREEHSRLSRSLD--EEVgrRRQLE-LEvRQlgARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRppaLQEk 1489
Cdd:COG1196    180 KLEATEENLERLEDilGEL--ERQLEpLE-RQ--AEKAERYRELKEELKELEAELLLLKLRELEAELEELEAE---LEE- 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1490 iimeevvklekdpdLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKtiyKEVIRVEKDpvlegerarv 1569
Cdd:COG1196    251 --------------LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---AELARLEQD---------- 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1570 weiLNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRL 1649
Cdd:COG1196    304 ---IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1650 LSQKTESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQETQTRE 1709
Cdd:COG1196    381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
 1888-1926 5.93e-10

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 56.18  E-value: 5.93e-10
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1720364114 1888 LLEAQAATGGIVDLLSRERYSVHKAVERGLIENTSTQRL 1926
Cdd:pfam00681    1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1356-1734 1.62e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.54  E-value: 1.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1356 LEKEAERLRQEVREAvQRRRATEDAVYELQNKLLLLERRRpeeqivvqevvvtqkdpkLREEHSRLSRSLDEEVGRRRQL 1435
Cdd:TIGR02168  198 LERQLKSLERQAEKA-ERYKELKAELRELELALLVLRLEE------------------LREELEELQEELKEAEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1436 ELEVRQLGARVEEeeARLSFEEDRSKKLAAERELRQLTLKIQELEKRppalqekiIMEEVVKLEkdpDLERSTEALRREL 1515
Cdd:TIGR02168  259 TAELQELEEKLEE--LRLEVSELEEEIEELQKELYALANEISRLEQQ--------KQILRERLA---NLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1516 DQEKNRVTELHRECQGLQVQVDLLQKtksqektiykevirvekdpVLEGERARvweiLNRERAARKGREEDVRSLQERID 1595
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELKE-------------------ELESLEAE----LEELEAELEELESRLEELEEQLE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1596 RAealrrswSREEAELQRARDQASqdcGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVTQLEAAI 1675
Cdd:TIGR02168  383 TL-------RSKVAQLELQIASLN---NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEEL 452

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720364114 1676 LQEKDKIYEKERTLRDLHTKVSREElnQETQTRETNLSTKICILEPETGNDMSPYEAYK 1734
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQAL--DAAERELAQLQARLDSLERLQENLEGFSEGVK 509
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1178-1482 2.45e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 62.45  E-value: 2.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1178 LLKEASRLRSLLEEEKNNNVALARELQELQEKYRVV---EKQKPKVQLQERVSEIFQVlpeTEQEIRRLRAQLQETGSKK 1254
Cdd:pfam17380  308 KAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAmerERELERIRQEERKRELERI---RQEEIAMEISRMRELERLQ 384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1255 SGVEQEVEKLLPELEVLRAQKPVVEYKE-------VTQEVVRHEKNPEVLREIDRLKAQ----LNELVNTNGRSQEQLIR 1323
Cdd:pfam17380  385 MERQQKNERVRQELEAARKVKILEEERQrkiqqqkVEMEQIRAEQEEARQREVRRLEEErareMERVRLEEQERQQQVER 464

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1324 LQGERDEWKRERSKVETKMVSKEVVRHEKDPVLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRpeeqivvq 1403
Cdd:pfam17380  465 LRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRR-------- 536

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720364114 1404 evvvtqkdpKLREEhsrlsrsldeevgRRRQLELEVRQlgaRVEEEEARLSfeEDRSKKLAAERElRQLTLKIQELEKR 1482
Cdd:pfam17380  537 ---------EAEEE-------------RRKQQEMEERR---RIQEQMRKAT--EERSRLEAMERE-REMMRQIVESEKA 587
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1079-1645 5.01e-09

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 61.30  E-value: 5.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1079 LTARLEELKDELlalEQKEMNVKEKVvvkevvkvekdLEMVKAAQTLRLQIEEDAARRKgaketvaKIQARIKDLEQAIS 1158
Cdd:pfam05557    7 SKARLSQLQNEK---KQMELEHKRAR-----------IELEKKASALKRQLDRESDRNQ-------ELQKRIRLLEKREA 65

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1159 SVEPKVIVKEVKKveqdpGLLKEASRLRSLLEEEKNNNVALARELQ-----ELQEKYRVVEKQKPKVQLQ----ERVSEI 1229
Cdd:pfam05557   66 EAEEALREQAELN-----RLKKKYLEALNKKLNEKESQLADAREVIsclknELSELRRQIQRAELELQSTnselEELQER 140

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1230 FQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVeyKEVTQEVVRHeknPEVLREIDRLK---AQ 1306
Cdd:pfam05557  141 LDLLKAKASEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSEIV--KNSKSELARI---PELEKELERLRehnKH 215

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1307 LNELVNTNGRSQEQ-------LIRLQGERDE---WKRERSKVETKMvsKEVVRHEKDPVLE-KEAERLRQEVREAVQRRR 1375
Cdd:pfam05557  216 LNENIENKLLLKEEvedlkrkLEREEKYREEaatLELEKEKLEQEL--QSWVKLAQDTGLNlRSPEDLSRRIEQLQQREI 293

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1376 ATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKL-REEHSRLSRSLDEEVgrrRQLELEVRQLGARVEEEEARLS 1454
Cdd:pfam05557  294 VLKEENSSLTSSARQLEKARRELEQELAQYLKKIEDLNKkLKRHKALVRRLQRRV---LLLTKERDGYRAILESYDKELT 370

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1455 FEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTEALRRELDQE-----KNRVTELHREC 1529
Cdd:pfam05557  371 MSNYSPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLAdpsysKEEVDSLRRKL 450

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1530 QGLQVQVDLLQKTK-SQEKTIYKEVIRVEKDPVlegeRARVWEI-LNRERAARKGREEDVRSLQERIDRAEALRRSWSRE 1607
Cdd:pfam05557  451 ETLELERQRLREQKnELEMELERRCLQGDYDPK----KTKVLHLsMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDD 526

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1720364114 1608 EAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQE 1645
Cdd:pfam05557  527 LEQVLRLPETTSTMNFKEVLDLRKELESAELKNQRLKE 564
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1460-1675 7.75e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 60.16  E-value: 7.75e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1460 SKKLAAERELRQLTLKIQELEKRppalQEKIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLL 1539
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKE----LAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1540 QKTKSQEKTIYKEVIRVEkdpVLEGERARVWEILNRERAARKGR-----EEDVRSLQERIDRAEALRRSWSREEAELQRA 1614
Cdd:COG4942     96 RAELEAQKEELAELLRAL---YRLGRQPPLALLLSPEDFLDAVRrlqylKYLAPARREQAEELRADLAELAALRAELEAE 172

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720364114 1615 RDQASQDCGRLQRQLRELEQQKQQKARQLQEegrlLSQKTESERQKAAQRSQAVTQLEAAI 1675
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLAR----LEKELAELAAELAELQQEAEELEALI 229
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 815-1661 8.77e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.14  E-value: 8.77e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  815 KLQAQKRLIQEilgrEQDQATVSRLTRDLQEALQDYELQA-DTYRCSLEPALAVSAPKRLRVISLQESIQAQEKNLAKAY 893
Cdd:pfam02463  171 KKEALKKLIEE----TENLAELIIDLEELKLQELKLKEQAkKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  894 TEVAA--AEQQQLRQLEFAKKMLRKKELDEDIQAIHSarQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQR 971
Cdd:pfam02463  247 RDEQEeiESSKQEIEKEEEKLAQVLKENKEEEKEKKL--QEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  972 LLQLRTQQPVARLEEKEVVEFYRDPQLESNLSQaasrvEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHLLTKEVTQ 1051
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEE-----EEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEL 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1052 IERDPGLDSQVTQLHS--EMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQI 1129
Cdd:pfam02463  400 KSEEEKEAQLLLELARqlEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1130 EEDAARRKGAKETVAKIQARIKDleqaiSSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNnVALARELQELQEK 1209
Cdd:pfam02463  480 VKLQEQLELLLSRQKLEERSQKE-----SKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN-YKVAISTAVIVEV 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1210 YRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQeTGSKKSGVEQEVEKLLPELEVLRAQKPVVE--------YK 1281
Cdd:pfam02463  554 SATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLK-SIAVLEIDPILNLAQLDKATLEADEDDKRAkvvegilkDT 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1282 EVTQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDPVLEKEAE 1361
Cdd:pfam02463  633 ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEEL 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1362 -RLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSLDEEVGRRRQL-ELEV 1439
Cdd:pfam02463  713 kKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKvEEEK 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1440 RQLGARVEEEEARLSFEEDRSKKLAAERELRQL-TLKIQELEKRPPALQEKIIMEEVVKLEKDP----------DLERST 1508
Cdd:pfam02463  793 EEKLKAQEEELRALEEELKEEAELLEEEQLLIEqEEKIKEEELEELALELKEEQKLEKLAEEELerleeeitkeELLQEL 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1509 EALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKS----QEKTIYKEVIRVEKDPVLEGERARVWEILNRERAARKGRE 1584
Cdd:pfam02463  873 LLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKlnllEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEE 952

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720364114 1585 EDVRSLQERIDRAEALRRSWSREEAElqrARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKA 1661
Cdd:pfam02463  953 NNKEEEEERNKRLLLAKEELGKVNLM---AIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELF 1026
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
907-1395 9.63e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 60.55  E-value: 9.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  907 LEFAKKMLRKKeLDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQPVARLEE 986
Cdd:COG4717     40 LAFIRAMLLER-LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEL 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  987 KEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHLLTKEVTQIERDPGLDSQVTQLH 1066
Cdd:COG4717    119 EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLA 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1067 SEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKETVAKI 1146
Cdd:COG4717    199 EELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGV 278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1147 QA------------RIKDLEQAISSVEPKVIVKEVKKVEQDpGLLKEASRLRSLLEEEKNNNVALARELQELQEKYRVVE 1214
Cdd:COG4717    279 LFlvlgllallfllLAREKASLGKEAEELQALPALEELEEE-ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1215 KQKPKVQLQERVSEIFQVLP----ETEQEIRRLRAQLqetgskksgveQEVEKLLPELEVLRAQkpVVEYKEVTQEVVRH 1290
Cdd:COG4717    358 ELEEELQLEELEQEIAALLAeagvEDEEELRAALEQA-----------EEYQELKEELEELEEQ--LEELLGELEELLEA 424

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1291 EKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVEtkmvskevvrhekdpvLEKEAERLRQEVREA 1370
Cdd:COG4717    425 LDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAE----------------LLQELEELKAELREL 488

                          490       500
                   ....*....|....*....|....*
gi 1720364114 1371 VQRRRATEDAVYELQNKLLLLERRR 1395
Cdd:COG4717    489 AEEWAALKLALELLEEAREEYREER 513
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 945-1340 1.19e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.47  E-value: 1.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  945 EVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQpvarleEKEVVEfyrdpqLESNLSQAASRVEEEGKRRARLQAELE 1024
Cdd:TIGR02169  666 ILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI------ENRLDE------LSQELSDASRKIGEIEKEIEQLEQEEE 733

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1025 AVAQKVVHLEGKRKTMQPHLLTKEvtqierdpgldsqvtqlhSEMQRLRGENGVLTARLEELKDELLALEQKEmnvkekv 1104
Cdd:TIGR02169  734 KLKERLEELEEDLSSLEQEIENVK------------------SELKELEARIEELEEDLHKLEEALNDLEARL------- 788

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1105 vvkevvkvekdlemvkaaqtLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVkevkkveqdpgLLKEASR 1184
Cdd:TIGR02169  789 --------------------SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEY-----------LEKEIQE 837

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1185 LRSLLEEEKNNNVALARELQELQEKYRVVEKQKPKVQLQERvsEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKL 1264
Cdd:TIGR02169  838 LQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR--DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1265 LPELEVLRAQKPVVEY--KEVTQEVVRHEKNPE-------VLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRER 1335
Cdd:TIGR02169  916 RKRLSELKAKLEALEEelSEIEDPKGEDEEIPEeelsledVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKR 995


                   ....*
gi 1720364114 1336 SKVET 1340
Cdd:TIGR02169  996 AKLEE 1000
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 666-1243 1.56e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 1.56e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  666 LEKQIQEADRVIQGFEAALALEgpvpegSGALQERVSELQRQRKELLQQQACVLGLHRQLKATEHACSALQNNFQEFCQD 745
Cdd:COG1196    244 LEAELEELEAELEELEAELAEL------EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  746 LPRQQRQVRALTDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDnlsswleqlphhrvqpsdgpsqisyklQAQKRLIQE 825
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA---------------------------EAEEALLEA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  826 ILGREQDQATVSRLTRDLQEALQDyELQADTYRCSLEPALAVSAPKRLRVISLQESIQAQEKNLAKAYTEVAAAEQQQLR 905
Cdd:COG1196    371 EAELAEAEEELEELAEELLEALRA-AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  906 -QLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQPVARL 984
Cdd:COG1196    450 eEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  985 EEKEVVEFYRDPQLESNLSQAasRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHLLTKEVTQIERDPGLDSQVTQ 1064
Cdd:COG1196    530 IGVEAAYEAALEAALAAALQN--IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1065 LHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKETVA 1144
Cdd:COG1196    608 LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1145 KIQARIKDLEQAISSVEpkVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVALARELQELQEKYRVVEKQKPKV--QL 1222
Cdd:COG1196    688 LAEEELELEEALLAEEE--EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDleEL 765

                          570       580
                   ....*....|....*....|.
gi 1720364114 1223 QERVSEIfqvlpetEQEIRRL 1243
Cdd:COG1196    766 ERELERL-------EREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 695-1481 1.81e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 1.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  695 GALQERVSELQRQRKELLQQQAcvlGLHRQLKATEHACSALQNNFQEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKIV 774
Cdd:TIGR02169  297 GELEAEIASLERSIAEKERELE---DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAEL 373

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  775 QDASLTYQQLRNSRDNLSSWLEQLPHHRvqpSDGPSQISYKLQAQKRLIQEILGREQDQATVSRLTRDLQEALQDYELQA 854
Cdd:TIGR02169  374 EEVDKEFAETRDELKDYREKLEKLKREI---NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEI 450

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  855 DTYRCSLEPALAVSAPKRLRVISLQESIQAQEKNLAKAYTEVAAAE--QQQLRQLEFAKKMLRKkELDEDIQAIHS--AR 930
Cdd:TIGR02169  451 KKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEaqARASEERVRGGRAVEE-VLKASIQGVHGtvAQ 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  931 QGSGSPAHARTAESE--------VLKTqlEEERKRVAEVQRDLEEQRQRLLQLRTQQPVARLEEK-----------EVVE 991
Cdd:TIGR02169  530 LGSVGERYATAIEVAagnrlnnvVVED--DAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSIlsedgvigfavDLVE 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  992 FyrDPQLESNLSQAASR---VE--EEGKR---RARLqaeleavaqkvVHLEGKrktmqphLLTKE---VTQIERDPGLDS 1060
Cdd:TIGR02169  608 F--DPKYEPAFKYVFGDtlvVEdiEAARRlmgKYRM-----------VTLEGE-------LFEKSgamTGGSRAPRGGIL 667

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1061 QVTQLHSEMQRLRgengvltARLEELKDELLALeQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARrkgAK 1140
Cdd:TIGR02169  668 FSRSEPAELQRLR-------ERLEGLKRELSSL-QSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK---LK 736

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1141 ETVAKIQARIKDLEQAISSVEpkvivkevkkveqdpgllKEASRLRSLLEEEKNNNVALARELQELQEKYRvvekqkpkv 1220
Cdd:TIGR02169  737 ERLEELEEDLSSLEQEIENVK------------------SELKELEARIEELEEDLHKLEEALNDLEARLS--------- 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1221 qlQERVSEIFQVLPETEQEIRRLRAQLQEtgskksgVEQEVEKLLPELEVLRAQkpvVEYKEVTQEVVRHEKNpEVLREI 1300
Cdd:TIGR02169  790 --HSRIPEIQAELSKLEEEVSRIEARLRE-------IEQKLNRLTLEKEYLEKE---IQELQEQRIDLKEQIK-SIEKEI 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1301 DRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMvskevvrhekdpvleKEAERLRQEVREAVQRRRateDA 1380
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL---------------RELERKIEELEAQIEKKR---KR 918

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1381 VYELQNKLLLLERRrpeeqivvqeVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLELEVRQLGA-------RVEEEEARL 1453
Cdd:TIGR02169  919 LSELKAKLEALEEE----------LSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPvnmlaiqEYEEVLKRL 988

                          810       820
                   ....*....|....*....|....*...
gi 1720364114 1454 SFEEDRSKKLAAERElrQLTLKIQELEK 1481
Cdd:TIGR02169  989 DELKEKRAKLEEERK--AILERIEEYEK 1014
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1459-1709 3.46e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 3.46e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1459 RSKKLAAERELRQ-------LTLKIQELEKRppalqekiimeeVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQG 1531
Cdd:COG1196    171 KERKEEAERKLEAteenlerLEDILGELERQ------------LEPLERQAEKAERYRELKEELKELEAELLLLKLRELE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1532 LQVQVDLLQKTKSQEKtiyKEVIRVEKDpVLEGERARVWEILNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAEL 1611
Cdd:COG1196    239 AELEELEAELEELEAE---LEELEAELA-ELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1612 QRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRD 1691
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                          250
                   ....*....|....*...
gi 1720364114 1692 LHTKVSREELNQETQTRE 1709
Cdd:COG1196    395 AAELAAQLEELEEAEEAL 412
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1414-1684 3.88e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.77  E-value: 3.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1414 LREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEkiime 1493
Cdd:COG4913    615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA----- 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1494 evvklekdpdLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIRVEKDPVLEGERARVWEIL 1573
Cdd:COG4913    690 ----------LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL 759

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1574 NRERAARKgreedVRSLQERIDRAEALRRswsREEAELQRARDQASQD----CGRLQRQLRELEQQkQQKARQLQEEGrL 1649
Cdd:COG4913    760 GDAVEREL-----RENLEERIDALRARLN---RAEEELERAMRAFNREwpaeTADLDADLESLPEY-LALLDRLEEDG-L 829

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1720364114 1650 LSQKTESERQKAAQRSQAVTQLEAAILQEKDKIYE 1684
Cdd:COG4913    830 PEYEERFKELLNENSIEFVADLLSKLRRAIREIKE 864
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1413-1716 4.97e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 58.21  E-value: 4.97e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1413 KLREEHSRLSRsldeEVGRRRQLELEVRQLGARVEEEEARLSFEEdrskKLAAERElRQLTLKIQELEKRPpalQEKIIM 1492
Cdd:pfam17380  300 RLRQEKEEKAR----EVERRRKLEEAEKARQAEMDRQAAIYAEQE----RMAMERE-RELERIRQEERKRE---LERIRQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1493 EEV-VKLEKDPDLER-------STEALRRELDQ-EKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIRvekdpvLE 1563
Cdd:pfam17380  368 EEIaMEISRMRELERlqmerqqKNERVRQELEAaRKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRR------LE 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1564 GERARVWEILNRERAARKGREEDVRSLQERIDRAealRRSWSREEAELQRARDQasqdcgrlQRQLRELEQQKQQKARQL 1643
Cdd:pfam17380  442 EERAREMERVRLEEQERQQQVERLRQQEEERKRK---KLELEKEKRDRKRAEEQ--------RRKILEKELEERKQAMIE 510

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720364114 1644 QEEGRLLSQKTESERQKAAQRSQavTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLSTKI 1716
Cdd:pfam17380  511 EERKRKLLEKEMEERQKAIYEEE--RRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQI 581
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 844-1524 7.16e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.81  E-value: 7.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  844 QEALQDYELQADTYRCSLEPALAVSAPKRLRVISLQESIQAQEKNLAKAYTEVAAAEQQQLRQLEFAKKMLRKKeLDEDI 923
Cdd:pfam05483   62 QEGLKDSDFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLK-LEEEI 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  924 QAIHSARQGSGSPAH---------ARTAESevlKTQLEEERKRVAEVQRDLEEQRQRLL----QLRTQQPVARLEekevV 990
Cdd:pfam05483  141 QENKDLIKENNATRHlcnllketcARSAEK---TKKYEYEREETRQVYMDLNNNIEKMIlafeELRVQAENARLE----M 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  991 EFyrdpQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHLLTK--EVTQIErdpgldsQVTQLHSE 1068
Cdd:pfam05483  214 HF----KLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESrdKANQLE-------EKTKLQDE 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1069 -MQRLRGENGVLTARLEELKDELlaleQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTlrlQIEEDAARRKGAKETVAKIQ 1147
Cdd:pfam05483  283 nLKELIEKKDHLTKELEDIKMSL----QRSMSTQKALEEDLQIATKTICQLTEEKEA---QMEELNKAKAAHSFVVTEFE 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1148 ARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVALARELQELQEKYRVVEKQKPKVQLQERV- 1226
Cdd:pfam05483  356 ATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELk 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1227 ---SEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELE---------VLRAQKPVVEYKEVTQE-------- 1286
Cdd:pfam05483  436 gkeQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEkeklknielTAHCDKLLLENKELTQEasdmtlel 515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1287 ------VVRHEKNPE-VLREIDRLKAQLNELVNTNGRSQEQLIRlQGERDEWKRERSKVETKMVSKEVVRHEKD-PVLEK 1358
Cdd:pfam05483  516 kkhqedIINCKKQEErMLKQIENLEEKEMNLRDELESVREEFIQ-KGDEVKCKLDKSEENARSIEYEVLKKEKQmKILEN 594

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1359 EAERLRQEVR-------------EAVQRRRATEDA---VYELQ-NKL-LLLERRRPEEQIVVQEVVVTQKDPKLREEH-- 1418
Cdd:pfam05483  595 KCNNLKKQIEnknknieelhqenKALKKKGSAENKqlnAYEIKvNKLeLELASAKQKFEEIIDNYQKEIEDKKISEEKll 674

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1419 ---SRLSRSLDEEVGRRRQLELEVRQlgaRVEEEEARLSFEEDRSKKLAAER--ELRQLTLKIQELEKRPPALQEKI--I 1491
Cdd:pfam05483  675 eevEKAKAIADEAVKLQKEIDKRCQH---KIAEMVALMEKHKHQYDKIIEERdsELGLYKNKEQEQSSAKAALEIELsnI 751

                          730       740       750
                   ....*....|....*....|....*....|....
gi 1720364114 1492 MEEVVKLEKDPDLER-STEALRRELDQEKNRVTE 1524
Cdd:pfam05483  752 KAELLSLKKQLEIEKeEKEKLKMEAKENTAILKD 785
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
942-1557 1.16e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.00  E-value: 1.16e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  942 AESEVLKTQLEEERKRVAEVQRDLEEQRQRLlqlrtqqpvarleekevvefyrdPQLESNLSQAASRVEEEGKRRarlqA 1021
Cdd:PRK03918   186 KRTENIEELIKEKEKELEEVLREINEISSEL-----------------------PELREELEKLEKEVKELEELK----E 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1022 ELEAVAQKVVHLEGKRKTMQphlltkevtqierdpgldsqvtqlhsemQRLRGengvLTARLEELKDELLALEQKEmnvk 1101
Cdd:PRK03918   239 EIEELEKELESLEGSKRKLE----------------------------EKIRE----LEERIEELKKEIEELEEKV---- 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1102 ekvvvkevvkveKDLEMVKAAQTLRLQIEEdaaRRKGAKETVAKIQARIKDLEQAISSVEPkvivkevkkveqdpgLLKE 1181
Cdd:PRK03918   283 ------------KELKELKEKAEEYIKLSE---FYEEYLDELREIEKRLSRLEEEINGIEE---------------RIKE 332

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1182 ASRLRSLLEEEKNNNVALARELQELQEKYRVVEKQKPKVQLQERVS---------EIFQVLPETEQEIRRLRAQLQETGS 1252
Cdd:PRK03918   333 LEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKkrltgltpeKLEKELEELEKAKEEIEEEISKITA 412

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1253 KKSGVEQEVEKLLPELEVLRAQKPV--VEYKEVTQEvvrHEKN--PEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGER 1328
Cdd:PRK03918   413 RIGELKKEIKELKKAIEELKKAKGKcpVCGRELTEE---HRKEllEEYTAELKRIEKELKEIEEKERKLRKELRELEKVL 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1329 DEWKRERSKVETKMVSKEVVRHEKDPVLEK------EAERLRQEVREAVQRRRATEDAV---YELQNKLLLLERRrpeeq 1399
Cdd:PRK03918   490 KKESELIKLKELAEQLKELEEKLKKYNLEElekkaeEYEKLKEKLIKLKGEIKSLKKELeklEELKKKLAELEKK----- 564

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1400 ivvqevvVTQKDPKLREEHSRLSR----SLDEEVGRRRQLE------LEVRQLGARVEEEEARLSFEEDRSKKlaAEREL 1469
Cdd:PRK03918   565 -------LDELEEELAELLKELEElgfeSVEELEERLKELEpfyneyLELKDAEKELEREEKELKKLEEELDK--AFEEL 635

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1470 RQLTLKIQELEKRPPALQEKIIMEEVVKL-EKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKT 1548
Cdd:PRK03918   636 AETEKRLEELRKELEELEKKYSEEEYEELrEEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEK 715


                   ....*....
gi 1720364114 1549 IYKEVIRVE 1557
Cdd:PRK03918   716 LEKALERVE 724
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1358-1713 1.38e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.70  E-value: 1.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1358 KEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLS---RSLDEEVGRRRQ 1434
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerlEELEERLEELRE 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1435 LELEVRQLGARVEEEEARLSFEEDRSKkLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTEALRRE 1514
Cdd:COG4717    161 LEEELEELEAELAELQEELEELLEQLS-LATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA 239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1515 LDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIRVekdpvLEGERARVWEILNRERAARKGREEDVRSLQERI 1594
Cdd:COG4717    240 ALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFL-----VLGLLALLFLLLAREKASLGKEAEELQALPALE 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1595 DRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQK---------TESERQKAAQRS 1665
Cdd:COG4717    315 ELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAallaeagveDEEELRAALEQA 394

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 1720364114 1666 QAVTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLS 1713
Cdd:COG4717    395 EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELE 442
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1503-1712 2.00e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.46  E-value: 2.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1503 DLERSTEALRRELDQEK--NRVTELHRECQGLQVQVDLLQktksQEKTIYKEVIRVEKDPVLEGERARVWEILNRERAAR 1580
Cdd:COG4913    236 DLERAHEALEDAREQIEllEPIRELAERYAAARERLAELE----YLRAALRLWFAQRRLELLEAELEELRAELARLEAEL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1581 KGREEDVRSLQERIDRAEALRRS--------WSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQ 1652
Cdd:COG4913    312 ERLEARLDALREELDELEAQIRGnggdrleqLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA 391

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720364114 1653 KTESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVS---------REELNQETQTRETNL 1712
Cdd:COG4913    392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSniparllalRDALAEALGLDEAEL 460
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 820-1696 2.27e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.50  E-value: 2.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  820 KRLIQEILGREQDQATVSRLTRDLQEALQDY--ELQADTYRCSlepalavsapkrlrviSLQESIQAQEKNLAKAYTEVA 897
Cdd:COG3096    281 RELSERALELRRELFGARRQLAEEQYRLVEMarELEELSARES----------------DLEQDYQAASDHLNLVQTALR 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  898 AAEQQQLRQLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLeeerkrvAEVQRDLEEQRQRLLQLrt 977
Cdd:COG3096    345 QQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQL-------ADYQQALDVQQTRAIQY-- 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  978 QQPVARLEEKEvvEFYRDPQLEsnlsqaasrVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPH---------LLTKE 1048
Cdd:COG3096    416 QQAVQALEKAR--ALCGLPDLT---------PENAEDYLAAFRAKEQQATEEVLELEQKLSVADAArrqfekayeLVCKI 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1049 VTQIERDPGLDSQVTQL--HSEMQRLRGENGVLTARLEELKDELLALEQ-KEMNVKEKVVVKEVVKVEKDLEMVKAAQTL 1125
Cdd:COG3096    485 AGEVERSQAWQTARELLrrYRSQQALAQRLQQLRAQLAELEQRLRQQQNaERLLEEFCQRIGQQLDAAEELEELLAELEA 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1126 RL-----QIEEDAARRKGAKETVAKIQARIKDLEQaissvepkvivkevkkveQDPGLLKEASRLRSLLE---EEKNNNV 1197
Cdd:COG3096    565 QLeeleeQAAEAVEQRSELRQQLEQLRARIKELAA------------------RAPAWLAAQDALERLREqsgEALADSQ 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1198 ALARELQELQEKYRVVEKQKPKVQLQERvseifqvlpETEQEIRRLraqlqetgSKKSGVEQevekllPELEVLRAQKPV 1277
Cdd:COG3096    627 EVTAAMQQLLEREREATVERDELAARKQ---------ALESQIERL--------SQPGGAED------PRLLALAERLGG 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1278 VEYKEVTQEVVRHE-----------KNPEVLREIDRLKAQLNELVNTngrsQEQLIRLQGER---DEWKRERSKVETKMV 1343
Cdd:COG3096    684 VLLSEIYDDVTLEDapyfsalygpaRHAIVVPDLSAVKEQLAGLEDC----PEDLYLIEGDPdsfDDSVFDAEELEDAVV 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1344 SK------EVVRHEKDPVL-----EKEAERLRQEvREAVQRRRATedAVYELQnkllllerrrpeeqivvqevvvtqkdp 1412
Cdd:COG3096    760 VKlsdrqwRYSRFPEVPLFgraarEKRLEELRAE-RDELAEQYAK--ASFDVQ--------------------------- 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1413 klreEHSRLSRSLDEEVGRRRQL------ELEVRQLGARVEEEEARLSFEEDRSKKLAAEreLRQLTLKIQELEKRPPal 1486
Cdd:COG3096    810 ----KLQRLHQAFSQFVGGHLAVafapdpEAELAALRQRRSELERELAQHRAQEQQLRQQ--LDQLKEQLQLLNKLLP-- 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1487 qekiimeeVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQV---QVDLLQKTKSQEKTIYKEVIRVEKdpVLE 1563
Cdd:COG3096    882 --------QANLLADETLADRLEELREELDAAQEAQAFIQQHGKALAQlepLVAVLQSDPEQFEQLQADYLQAKE--QQR 951

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1564 GERARVWEILN-RERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRL----------------- 1625
Cdd:COG3096    952 RLKQQIFALSEvVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYsqynqvlaslkssrdak 1031

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720364114 1626 QRQLRELEQQKQQKARQLQE--EGRLLSQKTESE---RQKAAQRSQAVTQL---EAAILQEKDKIYEKERTLRDLHTKV 1696
Cdd:COG3096   1032 QQTLQELEQELEELGVQADAeaEERARIRRDELHeelSQNRSRRSQLEKQLtrcEAEMDSLQKRLRKAERDYKQEREQV 1110
PLEC smart00250
Plectin repeat;
1924-1961 3.43e-07

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 48.25  E-value: 3.43e-07
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 1720364114  1924 QRLLNAQKAFTGIEDPVTRKRLSVGEAIQKGWMPQESV 1961
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1300-1711 9.11e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 9.11e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1300 IDRLKAQLNELVNTNGRsqeQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDPvLEKEAERLRQEVREAVQRRRATED 1379
Cdd:COG4717     48 LERLEKEADELFKPQGR---KPELNLKELKELEEELKEAEEKEEEYAELQEELEE-LEEELEELEAELEELREELEKLEK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1380 AVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEE--EARLSFEE 1457
Cdd:COG4717    124 LLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElqDLAEELEE 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1458 DRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQG-----L 1532
Cdd:COG4717    204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlflvL 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1533 QVQVDLLQKTKSQEKTIYKEVIRVEKDPVLEGERARVW-EILNRERAARKGREEDVRSLQERIDRAEALRRSWS--REEA 1609
Cdd:COG4717    284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELeELLAALGLPPDLSPEELLELLDRIEELQELLREAEelEEEL 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1610 ELQRARDQASQDCGRLQ-------RQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAvtQLEAAILQEKDKI 1682
Cdd:COG4717    364 QLEELEQEIAALLAEAGvedeeelRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE--ELEEELEELEEEL 441

                          410       420
                   ....*....|....*....|....*....
gi 1720364114 1683 YEKERTLRDLHTKvsREELNQETQTRETN 1711
Cdd:COG4717    442 EELEEELEELREE--LAELEAELEQLEED 468
PLEC smart00250
Plectin repeat;
1886-1919 1.02e-06

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 47.09  E-value: 1.02e-06
                            10        20        30
                    ....*....|....*....|....*....|....
gi 1720364114  1886 QKLLEAQAATGGIVDLLSRERYSVHKAVERGLIE 1919
Cdd:smart00250    1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLID 34
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1232-1710 1.22e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 1.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1232 VLPETEQEIRRLRAQLQETGSKK-----SGVEQEVEKLLPELEVLRAQKP-VVEYKEVTQEVV-RHEknpEVLREIDRLK 1304
Cdd:PRK02224   181 VLSDQRGSLDQLKAQIEEKEEKDlherlNGLESELAELDEEIERYEEQREqARETRDEADEVLeEHE---ERREELETLE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1305 AQLNELVNT-----------NGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDPvLEKEAERLRQEVREA-VQ 1372
Cdd:PRK02224   258 AEIEDLRETiaeterereelAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREE-LEDRDEELRDRLEECrVA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1373 RRRATEDAVYELQNKLLLLERRRpeeqivvqevvvtqkdpKLREEHSRLSRSLD---EEVGRRR----QLELEVRQLGAR 1445
Cdd:PRK02224   337 AQAHNEEAESLREDADDLEERAE-----------------ELREEAAELESELEearEAVEDRReeieELEEEIEELRER 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1446 VEEEEARLSFEEDRSKKLAAERE-----LRQLTLKIQELEKRPPALQEkiIMEEVVKLEKDPDLERSTEALRRELDQEkn 1520
Cdd:PRK02224   400 FGDAPVDLGNAEDFLEELREERDelrerEAELEATLRTARERVEEAEA--LLEAGKCPECGQPVEGSPHVETIEEDRE-- 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1521 RVTELHRECQGLQVQVDLLQKtksqektiykeviRVEKDPVLEGERARVWEILNRERAARKGREEDVRSLQERIDRAEAL 1600
Cdd:PRK02224   476 RVEELEAELEDLEEEVEEVEE-------------RLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEEL 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1601 RRSWSREEAELQRARDQAS---QDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESE--RQKAAQRSQAVTQLEAAI 1675
Cdd:PRK02224   543 RERAAELEAEAEEKREAAAeaeEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIAdaEDEIERLREKREALAELN 622

                          490       500       510
                   ....*....|....*....|....*....|....*
gi 1720364114 1676 LQEKDKIYEKERTLRDLHTKVSREELNQETQTRET 1710
Cdd:PRK02224   623 DERRERLAEKRERKRELEAEFDEARIEEAREDKER 657
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
939-1376 1.38e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.53  E-value: 1.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  939 ARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQL-RTQQPVARLEEkevvefYRDPQLESNLSQAASRVEEEGKRRA 1017
Cdd:PRK03918   328 ERIKELEEKEERLEELKKKLKELEKRLEELEERHELYeEAKAKKEELER------LKKRLTGLTPEKLEKELEELEKAKE 401

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1018 RLQAELEAVAQKVVHLEGKRKTMQPHLLT------------KEVTQIERDPGLDSqvtqLHSEMQRLRGENGVLTARLEE 1085
Cdd:PRK03918   402 EIEEEISKITARIGELKKEIKELKKAIEElkkakgkcpvcgRELTEEHRKELLEE----YTAELKRIEKELKEIEEKERK 477

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1086 LKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRlQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVI 1165
Cdd:PRK03918   478 LRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLE-ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKK 556

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1166 VKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVALARELQELQEKYRVVEKQKPKVQLQERvseifqvlpeTEQEIRRLRA 1245
Cdd:PRK03918   557 KLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELER----------EEKELKKLEE 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1246 QLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEknpevlREIDRLKAQLNELvntnGRSQEQLIRLQ 1325
Cdd:PRK03918   627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELS------RELAGLRAELEEL----EKRREEIKKTL 696

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720364114 1326 GERDEWKRERSKVEtkmvskevvrhEKDPVLEKEAERLrQEVREAVQRRRA 1376
Cdd:PRK03918   697 EKLKEELEEREKAK-----------KELEKLEKALERV-EELREKVKKYKA 735
PRK09039 PRK09039
peptidoglycan -binding protein;
1562-1695 1.93e-06

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 52.28  E-value: 1.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1562 LEGERARVWEILNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKAR 1641
Cdd:PRK09039    58 LNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARALA 137

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1720364114 1642 QLQeegrLLSQkteserQKAAQRSQaVTQLEAAILQEKDKIYEKERTLRDLHTK 1695
Cdd:PRK09039   138 QVE----LLNQ------QIAALRRQ-LAALEAALDASEKRDRESQAKIADLGRR 180
mukB PRK04863
chromosome partition protein MukB;
877-1708 2.22e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.04  E-value: 2.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  877 SLQESIQAQEKNLAKAYTEVAAAEQQQLRQLEFAKKMLRkkeLDEDIQAIHSAR-QGSGSPAHARTAESEV--LKTQLee 953
Cdd:PRK04863   325 DLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEER---LEEQNEVVEEADeQQEENEARAEAAEEEVdeLKSQL-- 399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  954 erkrvAEVQRDLEEQRQRLLQLrtQQPVARLEEKEvvEFYRDPQLEsnLSQAASRVEEegkrrarLQAELEAVAQKVVHL 1033
Cdd:PRK04863   400 -----ADYQQALDVQQTRAIQY--QQAVQALERAK--QLCGLPDLT--ADNAEDWLEE-------FQAKEQEATEELLSL 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1034 EGKRKTMQPH---------LLTKEVTQIERdpgldSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKV 1104
Cdd:PRK04863   462 EQKLSVAQAAhsqfeqayqLVRKIAGEVSR-----SEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAE 536

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1105 VVKEVVKVEKDLEMVKAAQTLRLQIEEDAaRRKGAKETVAKIQARIKDLEQAissvepkvivkevkkveqdpglLKEasr 1184
Cdd:PRK04863   537 RLLAEFCKRLGKNLDDEDELEQLQEELEA-RLESLSESVSEARERRMALRQQ----------------------LEQ--- 590

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1185 lrslLEEEKNNNVALARELQELQEKYRVVEKQKPKVQL-QERVSEIFQVLPETEQEIRRLRAQLQEtgsKKSGVEQEVEK 1263
Cdd:PRK04863   591 ----LQARIQRLAARAPAWLAAQDALARLREQSGEEFEdSQDVTEYMQQLLERERELTVERDELAA---RKQALDEEIER 663

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1264 L-------LPELEVLRAQKPVVEYKEVTQEVVRHE-----------KNPEVLREIDRLKAQLNELVNTngrsQEQLIRLQ 1325
Cdd:PRK04863   664 LsqpggseDPRLNALAERFGGVLLSEIYDDVSLEDapyfsalygpaRHAIVVPDLSDAAEQLAGLEDC----PEDLYLIE 739

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1326 GERDEWKRERSKVET--KMVSKEVV-------RHEKDPVL-----EKEAERLRQEvREAVQRRRATEDA-VYELQnklll 1390
Cdd:PRK04863   740 GDPDSFDDSVFSVEEleKAVVVKIAdrqwrysRFPEVPLFgraarEKRIEQLRAE-REELAERYATLSFdVQKLQ----- 813

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1391 lerrrpeeqivvqevvvtqkdpklreehsRLSRSLDEEVGRRRQL------ELEVRQLGARVEEEEARLSfeEDRSKKLA 1464
Cdd:PRK04863   814 -----------------------------RLHQAFSRFIGSHLAVafeadpEAELRQLNRRRVELERALA--DHESQEQQ 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1465 AERELRQLTLKIQELEKRPPA---LQEKIIMEEVVKLEKDpdLERSTEAlRRELDQEKNRVTELHRecqglqvQVDLLQK 1541
Cdd:PRK04863   863 QRSQLEQAKEGLSALNRLLPRlnlLADETLADRVEEIREQ--LDEAEEA-KRFVQQHGNALAQLEP-------IVSVLQS 932

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1542 TKSQEKTIYKEVIRVEKDpvLEGERARVWEILN-RERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQ 1620
Cdd:PRK04863   933 DPEQFEQLKQDYQQAQQT--QRDAKQQAFALTEvVQRRAHFSYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQ 1010

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1621 DcgrlQRQLRELEQ--QKQQKARQLQEEgrllsQKTESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRD----LHT 1694
Cdd:PRK04863  1011 A----QAQLAQYNQvlASLKSSYDAKRQ-----MLQELKQELQDLGVPADSGAEERARARRDELHARLSANRSrrnqLEK 1081

                          890
                   ....*....|....
gi 1720364114 1695 KVSREELNQETQTR 1708
Cdd:PRK04863  1082 QLTFCEAEMDNLTK 1095
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
842-1383 3.64e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  842 DLQEALQDYELQADTYRCSLEPALAVSAPKRLRvislQESIQAQEKNLAKAYTEVAAAEqqqlRQLEFAKKMLRkkELDE 921
Cdd:PRK02224   217 ELDEEIERYEEQREQARETRDEADEVLEEHEER----REELETLEAEIEDLRETIAETE----REREELAEEVR--DLRE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  922 DIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQ-----QPVARLEEKEVVEFYRDP 996
Cdd:PRK02224   287 RLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEaeslrEDADDLEERAEELREEAA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  997 QLESNLSQAASRVEEEGKRRARLQAELEAVAQKVvhlegkrktmqphlltkEVTQIERDpGLDSQVTQLHSEMQRLRGEN 1076
Cdd:PRK02224   367 ELESELEEAREAVEDRREEIEELEEEIEELRERF-----------------GDAPVDLG-NAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1077 GVLTARLEELKDELLALEQkemnVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQA 1156
Cdd:PRK02224   429 AELEATLRTARERVEEAEA----LLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDL 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1157 ------ISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKnnnvALARELQELQEKYRVVEKQKPKVqlQERVSEIF 1230
Cdd:PRK02224   505 veaedrIERLEERREDLEELIAERRETIEEKRERAEELRERAA----ELEAEAEEKREAAAEAEEEAEEA--REEVAELN 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1231 QVLPETEQEIRRLRAqLQETGSKKSGVEQEVEKLLPELEVLRAQKPvvEYKEVTQEvvRHEKNPEVLREIDrlKAQLNEL 1310
Cdd:PRK02224   579 SKLAELKERIESLER-IRTLLAAIADAEDEIERLREKREALAELND--ERRERLAE--KRERKRELEAEFD--EARIEEA 651

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720364114 1311 VNTNGRSQEQLIRLQGERDEWKRERSKVETK--MVSKEVvrhekdpvleKEAERLRQEvREAVQRRRATEDAVYE 1383
Cdd:PRK02224   652 REDKERAEEYLEQVEEKLDELREERDDLQAEigAVENEL----------EELEELRER-REALENRVEALEALYD 715
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 893-1657 4.06e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.28  E-value: 4.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  893 YTEVAAAEQQQLRQLEfAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRL 972
Cdd:TIGR00618  178 YTQLALMEFAKKKSLH-GKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  973 -LQLRTQQPVARLEEKEVVE-FYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKT--MQPHLLTKE 1048
Cdd:TIGR00618  257 kKQQLLKQLRARIEELRAQEaVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKllMKRAAHVKQ 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1049 VTQIERDPGLdsqVTQLHSEMQRLRGENGVLTARLEElKDELLALEQKemnvkekvVVKEVVKVEKDLEMVKAAQTLRLQ 1128
Cdd:TIGR00618  337 QSSIEEQRRL---LQTLHSQEIHIRDAHEVATSIREI-SCQQHTLTQH--------IHTLQQQKTTLTQKLQSLCKELDI 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1129 IEEDAArrkgakeTVAKIQARIKDLEQAISSVEPKVIVKevkkveqdpglLKEASRLRSLLEEEKNNNVALARELQELQE 1208
Cdd:TIGR00618  405 LQREQA-------TIDTRTSAFRDLQGQLAHAKKQQELQ-----------QRYAELCAAAITCTAQCEKLEKIHLQESAQ 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1209 KYRVVEKQ-KPKVQLQERVSEIfqvlpETEQEIRRLRAQLQETGSKKSGVEQEVEK---LLPELEVLRAQKPVVEYKEVT 1284
Cdd:TIGR00618  467 SLKEREQQlQTKEQIHLQETRK-----KAVVLARLLELQEEPCPLCGSCIHPNPARqdiDNPGPLTRRMQRGEQTYAQLE 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1285 QEV--VRHEKNPEvLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRErsKVETKMVSKEVVRHEKDPVLEKEAER 1362
Cdd:TIGR00618  542 TSEedVYHQLTSE-RKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNI--TVRLQDLTEKLSEAEDMLACEQHALL 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1363 LRQEVREAVQRRRATEDAV-YELQNKLLLLERRRPEEQIVVQevvvtqkdpklrEEHSRLSRSLDEEVGRRRQLELEvrq 1441
Cdd:TIGR00618  619 RKLQPEQDLQDVRLHLQQCsQELALKLTALHALQLTLTQERV------------REHALSIRVLPKELLASRQLALQ--- 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1442 lgarveeeearlsfeedrskklAAERELRQLTLKIQELEKRPPALQEkiimEEVVKLEKDP---DLERSTEALRRELDQE 1518
Cdd:TIGR00618  684 ----------------------KMQSEKEQLTYWKEMLAQCQTLLRE----LETHIEEYDRefnEIENASSSLGSDLAAR 737

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1519 KNRVTELHRECQGLQVQVdLLQKTKSQEKTIYKEVIRVEKDPVLEgERARVWEILNRERAARKGREEDVRS-LQERIDRA 1597
Cdd:TIGR00618  738 EDALNQSLKELMHQARTV-LKARTEAHFNNNEEVTAALQTGAELS-HLAAEIQFFNRLREEDTHLLKTLEAeIGQEIPSD 815

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720364114 1598 EALR----RSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESE 1657
Cdd:TIGR00618  816 EDILnlqcETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLN 879
PTZ00121 PTZ00121
MAEBL; Provisional
 853-1337 5.53e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 5.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  853 QADTYRCSLEPALAVSAPKRLRVISLQESIQAQEKNLAKAYTEVAAAEQQQLRQLEFAKKMLRKKELDEDIQAIHSARQG 932
Cdd:PTZ00121  1367 EAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA 1446

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  933 SGSPAHARTA-ESEVLKTQLEEERKrVAEVQRDLEEQRQ-RLLQLRTQQPVARLEEKEVVEFYRDPQLESNLSQAASRVE 1010
Cdd:PTZ00121  1447 DEAKKKAEEAkKAEEAKKKAEEAKK-ADEAKKKAEEAKKaDEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAD 1525

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1011 E----EGKRRARLQAELEAV--------AQKVVHLEGKRKTMQPHLLTKEVTQIERDPGLDSQVTQLHSEMQRLRGENGV 1078
Cdd:PTZ00121  1526 EakkaEEAKKADEAKKAEEKkkadelkkAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1079 LTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARrkgAKETVAKIQARIKDLEQAIS 1158
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK---AAEEAKKAEEDKKKAEEAKK 1682

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1159 SVEPKVIVKEVKKVEQDPGllKEASRLRSLLEEEKNNNVALARELQELQEKyrvVEKQKPKVQLQERVSEIFQVLPETEQ 1238
Cdd:PTZ00121  1683 AEEDEKKAAEALKKEAEEA--KKAEELKKKEAEEKKKAEELKKAEEENKIK---AEEAKKEAEEDKKKAEEAKKDEEEKK 1757

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1239 EIRRLRAQLQETGSK---------KSGVEQEVEKLLPELEvlRAQKPVVEYKEVTQEvVRHEKNPEVLREIDRLKAQLNE 1309
Cdd:PTZ00121  1758 KIAHLKKEEEKKAEEirkekeaviEEELDEEDEKRRMEVD--KKIKDIFDNFANIIE-GGKEGNLVINDSKEMEDSAIKE 1834

                          490       500
                   ....*....|....*....|....*...
gi 1720364114 1310 LVNTNGRSQEQLIRLQGERDEWKRERSK 1337
Cdd:PTZ00121  1835 VADSKNMQLEEADAFEKHKFNKNNENGE 1862
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
823-1045 7.29e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 7.29e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  823 IQEILGREQDQATVSRLTRDLQEALQDYELQADTYRCSLEPALAVSApkRLRVISLQESIQAQEKNLAKAYTEVAAAEQQ 902
Cdd:COG4913    240 AHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFA--QRRLELLEAELEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  903 QlrqlefakkmlrkKELDEDIQAIHSARQGSGspaharTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQPva 982
Cdd:COG4913    318 L-------------DALREELDELEAQIRGNG------GDRLEQLEREIERLERELEERERRRARLEALLAALGLPLP-- 376

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720364114  983 rLEEKEVVEFYRD-----PQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHLL 1045
Cdd:COG4913    377 -ASAEEFAALRAEaaallEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLL 443
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
666-1047 9.22e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 9.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  666 LEKQIQEADRVIQGFEAALALEGPVPEGSgALQERVSELQRQRKELLQQQACVLGLHRQLKATEHACSALQNNFQEFCQD 745
Cdd:COG4717    107 LEAELEELREELEKLEKLLQLLPLYQELE-ALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQ 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  746 L-PRQQRQVRALTDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDNLSSWLEQLPHHR---------------------- 802
Cdd:COG4717    186 LsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlkearlllliaaallallglg 265

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  803 VQPSDGPSQISYKLQAQKRLI----------QEILGREQDQATVSRLTRDLQEALQDYELQADTYRCSLEPALAVSAPKR 872
Cdd:COG4717    266 GSLLSLILTIAGVLFLVLGLLallflllareKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDR 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  873 LRviSLQESIQAQEKNLAKAYTEVAAAEQQQLRQL-------EFAKKMLRKKELDEDIQAIHSARQ-----GSGSPAHAR 940
Cdd:COG4717    346 IE--ELQELLREAEELEEELQLEELEQEIAALLAEagvedeeELRAALEQAEEYQELKEELEELEEqleelLGELEELLE 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  941 TAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQqpVARLEEKEVVEfyrdpQLESNLSQAASRVEEEGKRRARLQ 1020
Cdd:COG4717    424 ALDEEELEEELEELEEELEELEEELEELREELAELEAE--LEQLEEDGELA-----ELLQELEELKAELRELAEEWAALK 496

                          410       420
                   ....*....|....*....|....*..
gi 1720364114 1021 AELEAVAQkvvHLEGKRKTMQPHLLTK 1047
Cdd:COG4717    497 LALELLEE---AREEYREERLPPVLER 520
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1178-1766 1.32e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.74  E-value: 1.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1178 LLKEASRLRSLLEEEKNNNvALARELQELQEK---YRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKK 1254
Cdd:pfam02463  158 IEEEAAGSRLKRKKKEALK-KLIEETENLAELiidLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1255 SGVEQEVEKLLPELEVLRA--QKPVVEYKEVTQEVVRHEKNPEVLREIDRLKAQLNELVNTNgRSQEQLIRLQGERDEWK 1332
Cdd:pfam02463  237 ERIDLLQELLRDEQEEIESskQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEEL-KSELLKLERRKVDDEEK 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1333 RERSKVETKMVSKEVVRHEK----DPVLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVT 1408
Cdd:pfam02463  316 LKESEKEKKKAEKELKKEKEeieeLEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1409 QKDPKLREEHSRLSRsLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQE 1488
Cdd:pfam02463  396 ELELKSEEEKEAQLL-LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1489 KIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIY----KEVIRVEKDPVLEG 1564
Cdd:pfam02463  475 KETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVavenYKVAISTAVIVEVS 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1565 ERARVWEILNRERAARKGREEDVRSLQERIDRAEALRRSWSREE--AELQRARDQASQDCGRLQRQLRELEQQKQQKARQ 1642
Cdd:pfam02463  555 ATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1643 LQEEGRLLSQKTESERQKAAQRSQAVTQLEAAILQEKDKIY-------EKERTLRDLHTKVSREELNQETQTRETNLSTK 1715
Cdd:pfam02463  635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELleiqelqEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720364114 1716 ICILEPETGNDMSPYEAYKRGVIDRGQYLQLQELECDWEEVTTSSPCGEES 1766
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEE 765
SPEC cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ...
 302-387 1.62e-05

Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here


Pssm-ID: 238103 [Multi-domain]  Cd Length: 213  Bit Score: 48.21  E-value: 1.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  302 QHELLAQERSINQLEDDADRMVELGHPAIGPIQVHQEALKMEWQNFLNLCICQESQLQRVEDYRRFQEEADSVSQTLAKL 381
Cdd:cd00176     46 EAELAAHEERVEALNELGEQLIEEGHPDAEEIQERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEK 125


                   ....*.
gi 1720364114  382 SSNLDT 387
Cdd:cd00176    126 EAALAS 131
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 833-1714 1.96e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.05  E-value: 1.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  833 QATVSRLTRDLQEALQDYELQADTYRCSLEPALAVSAPkrlrvISLQESIQAQEKNLAKAYTEvaAAEQQQLRQLEFAKK 912
Cdd:TIGR00606  188 LETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQ-----ITSKEAQLESSREIVKSYEN--ELDPLKNRLKEIEHN 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  913 MLRKKELDEDIQAIHSarqgsgspahaRTAESEVLKTQLEEERKRV----AEVQRDLEEQRQRllqlrtqqpVARLEEKE 988
Cdd:TIGR00606  261 LSKIMKLDNEIKALKS-----------RKKQMEKDNSELELKMEKVfqgtDEQLNDLYHNHQR---------TVREKERE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  989 VVEFYRDPQLESNLSQAASRVEEEGK-RRARLQAELEAVAQKVVHLEGKRKTMQPHLltkEVTQIERDPGLDSQVTQLHS 1067
Cdd:TIGR00606  321 LVDCQRELEKLNKERRLLNQEKTELLvEQGRLQLQADRHQEHIRARDSLIQSLATRL---ELDGFERGPFSERQIKNFHT 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1068 -EMQRLRGENGVLTARLEELKDELlALEQKEMNVKEKVVVKEVVKVEKDLEMV-KAAQTLRLQIEEDAARRKGAKETVAK 1145
Cdd:TIGR00606  398 lVIERQEDEAKTAAQLCADLQSKE-RLKQEQADEIRDEKKGLGRTIELKKEILeKKQEELKFVIKELQQLEGSSDRILEL 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1146 IQARIKDLEQAI-----SSVEPKVIVKEVKKVEQ---DPGLLKEASRLRSL--LEEEKNNNVALARELQELQEKYRVVEK 1215
Cdd:TIGR00606  477 DQELRKAERELSkaeknSLTETLKKEVKSLQNEKadlDRKLRKLDQEMEQLnhHTTTRTQMEMLTKDKMDKDEQIRKIKS 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1216 QKP------------KVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPEL--------EVLRAQK 1275
Cdd:TIGR00606  557 RHSdeltsllgyfpnKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLssyedklfDVCGSQD 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1276 PVVEYKEVTQEVVRHEKNPEVLREIDRLKAQ-LNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDP 1354
Cdd:TIGR00606  637 EESDLERLKEEIEKSSKQRAMLAGATAVYSQfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTES 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1355 VLEKEaERLRQEVREAVQRRRA----TEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSlDEEVG 1430
Cdd:TIGR00606  717 ELKKK-EKRRDEMLGLAPGRQSiidlKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLT-DVTIM 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1431 RRRQLELE-----VRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKII-MEEVVKLEKDPDL 1504
Cdd:TIGR00606  795 ERFQMELKdverkIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQhLKSKTNELKSEKL 874

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1505 ERSTEALRREldQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTiykevirvekdpVLEGERARVWEILNRERAARKGRE 1584
Cdd:TIGR00606  875 QIGTNLQRRQ--QFEEQLVELSTEVQSLIREIKDAKEQDSPLET------------FLEKDQQEKEELISSKETSNKKAQ 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1585 EDVRSLQERIDRAEALRRSWSREEAE-LQRARDQASQDCGRLQRQLRELEQQKQqkarQLQEEGRLLSQKTESERQKaaq 1663
Cdd:TIGR00606  941 DKVNDIKEKVKNIHGYMKDIENKIQDgKDDYLKQKETELNTVNAQLEECEKHQE----KINEDMRLMRQDIDTQKIQ--- 1013

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1720364114 1664 rsQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSRE---ELNQETQTRETNLST 1714
Cdd:TIGR00606 1014 --ERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMqvlQMKQEHQKLEENIDL 1065
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
 1967-2002 2.13e-05

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 43.09  E-value: 2.13e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1720364114 1967 VQHLTGGLIDPKRTGRIPVPQAVLCGMISEDLGQLL 2002
Cdd:pfam00681    4 AQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1294-1488 2.98e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1294 PEVLREIDRLKAQLNELVNTNGRS---QEQLIRLQGERDEWKRERSKVETKMVSKEVV-------RHEKDPVLEKEAERL 1363
Cdd:COG4913    221 PDTFEAADALVEHFDDLERAHEALedaREQIELLEPIRELAERYAAARERLAELEYLRaalrlwfAQRRLELLEAELEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1364 RQEVREAVQRRRATEDAVYELQNKLLLLERRRpeeqivvQEVVVTQKDPkLREEHSRLSRSLDEEVGRRRQLELEVRQLG 1443
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQI-------RGNGGDRLEQ-LEREIERLERELEERERRRARLEALLAALG 372

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720364114 1444 ARV-----------------------EEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKR----PPALQE 1488
Cdd:COG4913    373 LPLpasaeefaalraeaaallealeeELEALEEALAEAEAALRDLRRELRELEAEIASLERRksniPARLLA 444
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
880-1442 3.84e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 3.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  880 ESIQAQEKNLAKAYTEVAAAEQQ--QLRQL-----EFAKKMLRKKELDEDIQAIHS-ARQGSGSPAHARTAESEVLKTQL 951
Cdd:COG4913    228 DALVEHFDDLERAHEALEDAREQieLLEPIrelaeRYAAARERLAELEYLRAALRLwFAQRRLELLEAELEELRAELARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  952 EEERKRVAEVQRDLEEQRQRLLQLRTQQPVARLEekevvefyrdpQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVV 1031
Cdd:COG4913    308 EAELERLEARLDALREELDELEAQIRGNGGDRLE-----------QLEREIERLERELEERERRRARLEALLAALGLPLP 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1032 HLEGKRKTMQphlltKEVTQieRDPGLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVkekvvvkevvk 1111
Cdd:COG4913    377 ASAEEFAALR-----AEAAA--LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNI----------- 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1112 vekDLEMVKAAQTLR----------------LQIEEDAARRKGAKETVAKIQARI-----KDLEQAISSVEP-------- 1162
Cdd:COG4913    439 ---PARLLALRDALAealgldeaelpfvgelIEVRPEEERWRGAIERVLGGFALTllvppEHYAAALRWVNRlhlrgrlv 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1163 ----KVIVKEVKKVEQDPG-----LLKEASRLRSLLEEE--KNNNVALARELQELQ-------------EKYRVVEKQKP 1218
Cdd:COG4913    516 yervRTGLPDPERPRLDPDslagkLDFKPHPFRAWLEAElgRRFDYVCVDSPEELRrhpraitragqvkGNGTRHEKDDR 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1219 KVQLQERVseIFQvlpETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPVVE-YKEVTQEVVRHeknPEVL 1297
Cdd:COG4913    596 RRIRSRYV--LGF---DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrLAEYSWDEIDV---ASAE 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1298 REIDRLKAQLNELVNTNGrsqeQLIRLQGERDEWKRERSKVETKmvsKEVVRHEKDpVLEKEAERLRQEVREAVQRRRAT 1377
Cdd:COG4913    668 REIAELEAELERLDASSD----DLAALEEQLEELEAELEELEEE---LDELKGEIG-RLEKELEQAEEELDELQDRLEAA 739

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720364114 1378 EDAVYELQNklLLLERRRPEEQIvvqevvvtqkDPKLREEHSRLSRSLDEEVGRRRQLELEVRQL 1442
Cdd:COG4913    740 EDLARLELR--ALLEERFAAALG----------DAVERELRENLEERIDALRARLNRAEEELERA 792
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1188-1727 3.97e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.07  E-value: 3.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1188 LLEEEKNNNVALARELQELQEKYRVVEKQKPKvqLQERVSEifqVLPETEQEIRRLRAQLQE----TGSKKSGVEQEVEK 1263
Cdd:pfam12128  245 KLQQEFNTLESAELRLSHLHFGYKSDETLIAS--RQEERQE---TSAELNQLLRTLDDQWKEkrdeLNGELSAADAAVAK 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1264 LLPELEVLRAQKPVVEYKEVTQEVVRHEKNPEVLREIDRLKAQLnELVNTNGRSQEQlirlqgerdEWKRERSKVETKMV 1343
Cdd:pfam12128  320 DRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERL-KALTGKHQDVTA---------KYNRRRSKIKEQNN 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1344 SKEVVRHEKDPVLEKEAERLRQEVREAVQR-----RRATEDAVYELQNKLLLLERRrpeeqivVQEVVVTQKDPKLREEH 1418
Cdd:pfam12128  390 RDIAGIKDKLAKIREARDRQLAVAEDDLQAleselREQLEAGKLEFNEEEYRLKSR-------LGELKLRLNQATATPEL 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1419 SRLSRSLDEEVGRRRQlelevRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKL 1498
Cdd:pfam12128  463 LLQLENFDERIERARE-----EQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLL 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1499 E----KDPDLERSteaLRRELDQEKNRVTELHRECQGLQVqvdllqktkSQEKTIYKEVIRVEKDPVleGERARVWEILN 1574
Cdd:pfam12128  538 HflrkEAPDWEQS---IGKVISPELLHRTDLDPEVWDGSV---------GGELNLYGVKLDLKRIDV--PEWAASEEELR 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1575 RERAARKGREEDVRSLQERIDRAEALRR----SWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQkarQLQEEGRll 1650
Cdd:pfam12128  604 ERLDKAEEALQSAREKQAAAEEQLVQANgeleKASREETFARTALKNARLDLRRLFDEKQSEKDKKNK---ALAERKD-- 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1651 sQKTESERQKAAQRSQAVTQLEAAILQEKDKIYEkERTLRDLHTKVSREE-------LNQETQTRETNLSTKICILEPET 1723
Cdd:pfam12128  679 -SANERLNSLEAQLKQLDKKHQAWLEEQKEQKRE-ARTEKQAYWQVVEGAldaqlalLKAAIAARRSGAKAELKALETWY 756


                   ....
gi 1720364114 1724 GNDM 1727
Cdd:pfam12128  757 KRDL 760
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1438-1705 4.08e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.91  E-value: 4.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1438 EVRQLGARVEEEEARLSFEEDRSKKLAAERELRqltLKIQELEKRPPALQEKIIMEEVVKLEKD-PDLERSTEALRRELD 1516
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREKA---ERYQALLKEKREYEGYELLKEKEALERQkEAIERQLASLEEELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1517 QEKNRVTELHRECQglQVQVDLLQKTKSQEKTIYKEVIRVEKD-PVLEGERARVWEILNRERAARKGREEDVRSLQERID 1595
Cdd:TIGR02169  255 KLTEEISELEKRLE--EIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEKERELEDAEERLAKLEAEID 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1596 RAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQ---------------KTESER-- 1658
Cdd:TIGR02169  333 KLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDyrekleklkreinelKRELDRlq 412

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1720364114 1659 QKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQET 1705
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ 459
PTZ00121 PTZ00121
MAEBL; Provisional
 878-1371 4.19e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.98  E-value: 4.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  878 LQESIQAQEKNLAKAYTEVAAAEQQQLRQLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKR 957
Cdd:PTZ00121  1359 AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK 1438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  958 VAEVQRDLEEQRQRLLQLR-TQQPVARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRA---RLQAELEAVAQKVVHL 1033
Cdd:PTZ00121  1439 KAEEAKKADEAKKKAEEAKkAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKAdeaKKAAEAKKKADEAKKA 1518

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1034 EGKRKtmqphllTKEVTQIERDPGLDsqvtQLHSEMQRLRGENgvlTARLEELK--DELLALEQKEMNVKEKVVVKEVVK 1111
Cdd:PTZ00121  1519 EEAKK-------ADEAKKAEEAKKAD----EAKKAEEKKKADE---LKKAEELKkaEEKKKAEEAKKAEEDKNMALRKAE 1584

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1112 VEKDLEMVKAAQTLRLQIEEDAARRKGA-KETVAKIQA-RIKDLEQAISSVEPKVIVKEVKKveqdpgllKEASRLRsll 1189
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYEEEKKMKAEEAkKAEEAKIKAeELKKAEEEKKKVEQLKKKEAEEK--------KKAEELK--- 1653

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1190 EEEKNNNVALARELQELQEKYRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELE 1269
Cdd:PTZ00121  1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAE 1733

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1270 vlRAQKPVVEYKEVTQEVvrhEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKR----ERSKVETKMVSK 1345
Cdd:PTZ00121  1734 --EAKKEAEEDKKKAEEA---KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRrmevDKKIKDIFDNFA 1808

                          490       500
                   ....*....|....*....|....*...
gi 1720364114 1346 EVVR--HEKDPVLEKEAERLRQEVREAV 1371
Cdd:PTZ00121  1809 NIIEggKEGNLVINDSKEMEDSAIKEVA 1836
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1359-1528 4.50e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 48.70  E-value: 4.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1359 EAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREehsrlsrsLDEEVGRrrqLELE 1438
Cdd:COG2433    360 PPDVDRDEVKARVIRGLSIEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRR--------LEEQVER---LEAE 428

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1439 VRQLGARVEEEEARLSFEEDRSKKLAAERElrqltlkiQELEKRppalqekiimEEVVKLEkdpdleRSTEALRRELDQE 1518
Cdd:COG2433    429 VEELEAELEEKDERIERLERELSEARSEER--------REIRKD----------REISRLD------REIERLERELEEE 484

                          170
                   ....*....|
gi 1720364114 1519 KNRVTELHRE 1528
Cdd:COG2433    485 RERIEELKRK 494
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1016-1488 4.68e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.61  E-value: 4.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1016 RARLQAELEAVAQKVVHLEGKRKTMQPHLLTKEVTQIERdpgLDSQVTQLHSEMQRLRGengvLTARLEELKDELLALEQ 1095
Cdd:COG4717     44 RAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKE---AEEKEEEYAELQEELEE----LEEELEELEAELEELRE 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1096 KEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRL-QIEEDAARRKGAKETVAKIQARIKDLEQAIssvEPKVIVKEVKKVEQ 1174
Cdd:COG4717    117 ELEKLEKLLQLLPLYQELEALEAELAELPERLeELEERLEELRELEEELEELEAELAELQEEL---EELLEQLSLATEEE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1175 DPGLLKEASRLRSLLEEEKNNNVALARELQELQEKYRVVEKQKPKVQLQERVSE--IFQVLPETEQEIRRLRAQLQETGS 1252
Cdd:COG4717    194 LQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEarLLLLIAAALLALLGLGGSLLSLIL 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1253 KKSGVEQEVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWK 1332
Cdd:COG4717    274 TIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL 353

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1333 RERSKVETKMvSKEVVRHEKDPVLEKEAERLRQEVREAVQRRRATEdavyELQNKLLLLERRRPEEQIVVQEVVVTQKDP 1412
Cdd:COG4717    354 REAEELEEEL-QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQ----ELKEELEELEEQLEELLGELEELLEALDEE 428

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1413 KLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQL----------------TLKI 1476
Cdd:COG4717    429 ELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELaeewaalklalelleeAREE 508

                          490
                   ....*....|..
gi 1720364114 1477 QELEKRPPALQE 1488
Cdd:COG4717    509 YREERLPPVLER 520
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1060-1553 5.26e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.48  E-value: 5.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1060 SQVTQLHSEMQRLRGENGVLTARLEELKDELLALE------QKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDA 1133
Cdd:TIGR04523  145 TEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEkeklniQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELK 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1134 ARRKGAKETVAKIQARIKDLEQAISSVEpkviVKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVALARELQELQEKYRVV 1213
Cdd:TIGR04523  225 KQNNQLKDNIEKKQQEINEKTTEISNTQ----TQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDL 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1214 EKQK-----------------PKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQkp 1276
Cdd:TIGR04523  301 NNQKeqdwnkelkselknqekKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE-- 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1277 vveykevtqevvrhekNPEVLREIDRLKAQLNELvntngrsqEQLIRLQGERDEWKRErsKVETKMVSKEvvrhekdpVL 1356
Cdd:TIGR04523  379 ----------------NQSYKQEIKNLESQINDL--------ESKIQNQEKLNQQKDE--QIKKLQQEKE--------LL 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1357 EKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKdpKLREEHSRLSRSLDEEVGRRRQLE 1436
Cdd:TIGR04523  425 EKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSIN--KIKQNLEQKQKELKSKEKELKKLN 502

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1437 LEVRQLGARVEEEEARLSFEEDRSKKLaaERELRQLTLKIQELEKrppalqEKIIMEEVVKLEKdpdLERSTEALRRELD 1516
Cdd:TIGR04523  503 EEKKELEEKVKDLTKKISSLKEKIEKL--ESEKKEKESKISDLED------ELNKDDFELKKEN---LEKEIDEKNKEIE 571

                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 1720364114 1517 QEKNRVTELHRECQGLQvqvDLLQKTKSQEKTIYKEV 1553
Cdd:TIGR04523  572 ELKQTQKSLKKKQEEKQ---ELIDQKEKEKKDLIKEI 605
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1413-1674 5.36e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.63  E-value: 5.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1413 KLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAEREL-----RQLTLKIQELEKRPPAL- 1486
Cdd:pfam01576  100 KMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLleeriSEFTSNLAEEEEKAKSLs 179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1487 -----QEKIIMEEVVKLEKDPDLERSTEALRRELDQEknrVTELHRECQGLQVQV-DLLQKTKSQEKTIYKEVIRVEKDP 1560
Cdd:pfam01576  180 klknkHEAMISDLEERLKKEEKGRQELEKAKRKLEGE---STDLQEQIAELQAQIaELRAQLAKKEEELQAALARLEEET 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1561 V-----------LEGERARVWEILNRERAARkgreedvrslqeriDRAEALRRSWSrEEAELQRARDQASQDCGRLQRQL 1629
Cdd:pfam01576  257 AqknnalkkireLEAQISELQEDLESERAAR--------------NKAEKQRRDLG-EELEALKTELEDTLDTTAAQQEL 321

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1720364114 1630 R-ELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVT-QLEAA 1674
Cdd:pfam01576  322 RsKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTeQLEQA 368
mukB PRK04863
chromosome partition protein MukB;
878-1515 5.82e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.41  E-value: 5.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  878 LQESIQAQEKNLAkayTEVAAAEQQ------QLRQLEFAKKMLRKkeLDEDI---QAIHSARQgsgspAHARTAESEVLK 948
Cdd:PRK04863   443 WLEEFQAKEQEAT---EELLSLEQKlsvaqaAHSQFEQAYQLVRK--IAGEVsrsEAWDVARE-----LLRRLREQRHLA 512

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  949 TQLEEERKRVAEVQRDLEEQR--QRLLQLRTQQPVARLEEKEVVEFYRDpQLESNLSQAASRVEEEGKRRARLQAELEAV 1026
Cdd:PRK04863   513 EQLQQLRMRLSELEQRLRQQQraERLLAEFCKRLGKNLDDEDELEQLQE-ELEARLESLSESVSEARERRMALRQQLEQL 591

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1027 AQKVVHLEGKR----------------------------KTMQPHLLTKEVTQIERDpGLDSQVTQLHSEMQRLRGENGV 1078
Cdd:PRK04863   592 QARIQRLAARApawlaaqdalarlreqsgeefedsqdvtEYMQQLLERERELTVERD-ELAARKQALDEEIERLSQPGGS 670

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1079 LTARLEELKDELLALEQKEMnvkekvvvkevvkvEKDLEMVKAAQT------LRLQI---EEDAARRKGAK-----ETVA 1144
Cdd:PRK04863   671 EDPRLNALAERFGGVLLSEI--------------YDDVSLEDAPYFsalygpARHAIvvpDLSDAAEQLAGledcpEDLY 736

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1145 KIQARIKDLEQAISSVEPKVIVKEVKKVEQD---------PgLLKEASRlRSLLEEeknnnvaLARELQELQEKYrvvEK 1215
Cdd:PRK04863   737 LIEGDPDSFDDSVFSVEELEKAVVVKIADRQwrysrfpevP-LFGRAAR-EKRIEQ-------LRAEREELAERY---AT 804

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1216 QKPKVQLQERVSEIFQVL----------PETEQEIRRLRAQLQETGSKKSGVE-----------------QEVEKLLPEL 1268
Cdd:PRK04863   805 LSFDVQKLQRLHQAFSRFigshlavafeADPEAELRQLNRRRVELERALADHEsqeqqqrsqleqakeglSALNRLLPRL 884

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1269 EVLRAQKPVVEYKEVTQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVS-KEV 1347
Cdd:PRK04863   885 NLLADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFAlTEV 964

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1348 VR-------HEKDPVLEKEA---ERLRQEVREAVQRRRATEDAVYELQNKLlllerrrpEEQIVVQEVVVTQKDPKlREE 1417
Cdd:PRK04863   965 VQrrahfsyEDAAEMLAKNSdlnEKLRQRLEQAEQERTRAREQLRQAQAQL--------AQYNQVLASLKSSYDAK-RQM 1035

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1418 HSRLSRSLDEeVGRRRQLELEVRqLGARVEEEEARLSfeEDRSKKLAAERELRQLTLKIQELEKRPPALQEKI-IMEE-- 1494
Cdd:PRK04863  1036 LQELKQELQD-LGVPADSGAEER-ARARRDELHARLS--ANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYhEMREqv 1111

                          730       740       750
                   ....*....|....*....|....*....|
gi 1720364114 1495 ---------VVKLEKDPDLERSTEalRREL 1515
Cdd:PRK04863  1112 vnakagwcaVLRLVKDNGVERRLH--RREL 1139
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1117-1704 6.12e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.09  E-value: 6.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1117 EMVKAAQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNN 1196
Cdd:TIGR04523   37 QLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDK 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1197 ---VALARELQELQEKYRVVEKQKPKVqlqerVSEIF---QVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEV 1270
Cdd:TIGR04523  117 eqkNKLEVELNKLEKQKKENKKNIDKF-----LTEIKkkeKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDK 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1271 LRAQKPVVEYKeVTQEVVRHEKNPEVLREIDRLKAQLNELvntngrsQEQLIRLQGERDEWKRERSKVETKM-VSKEVVR 1349
Cdd:TIGR04523  192 IKNKLLKLELL-LSNLKKKIQKNKSLESQISELKKQNNQL-------KDNIEKKQQEINEKTTEISNTQTQLnQLKDEQN 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1350 HEKDPVLEKEaerlrQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSLDeev 1429
Cdd:TIGR04523  264 KIKKQLSEKQ-----KELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNK--- 335

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1430 gRRRQLELEVRQLgarveEEEARLSFEEDRSKKlaaerelRQLTLKIQELEKrppalqekIIMEEVVKLEKDPDLERSTE 1509
Cdd:TIGR04523  336 -IISQLNEQISQL-----KKELTNSESENSEKQ-------RELEEKQNEIEK--------LKKENQSYKQEIKNLESQIN 394

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1510 ALRRELDQEKNRVTELHRECQGLQVQVDLLQKtksqEKTIYKEVIRVEKDPVLEgerarvweiLNRERAARkgrEEDVRS 1589
Cdd:TIGR04523  395 DLESKIQNQEKLNQQKDEQIKKLQQEKELLEK----EIERLKETIIKNNSEIKD---------LTNQDSVK---ELIIKN 458

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1590 LQERIDRAEALRRSWSREEAELQRARDQASQDcgrLQRQLRELEQQKQQKaRQLQEEGRLLSQKTESERQKAAQRSQAVT 1669
Cdd:TIGR04523  459 LDNTRESLETQLKVLSRSINKIKQNLEQKQKE---LKSKEKELKKLNEEK-KELEEKVKDLTKKISSLKEKIEKLESEKK 534

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1720364114 1670 QLEAAILQEKDKIYEKERTLRDLHTKVSREELNQE 1704
Cdd:TIGR04523  535 EKESKISDLEDELNKDDFELKKENLEKEIDEKNKE 569
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1199-1687 6.20e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.23  E-value: 6.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1199 LARELQELQEKYRVVEKQKPKVQLQE--RVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKp 1276
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKElkELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL- 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1277 vvEYKEVTQEVVRHEknpevlREIDRLKAQLNELVntngRSQEQLIRLQGERDEWKRERSKVETKMVSKevvRHEKDPVL 1356
Cdd:COG4717    126 --QLLPLYQELEALE------AELAELPERLEELE----ERLEELRELEEELEELEAELAELQEELEEL---LEQLSLAT 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1357 EKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLE 1436
Cdd:COG4717    191 EEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1437 LEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEkrppALQEKIIMEEVVKLEKDPDLERS-TEALRREL 1515
Cdd:COG4717    271 LILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALE----ELEEEELEELLAALGLPPDLSPEeLLELLDRI 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1516 DQEKNRVTELHRECQglQVQVDLLQKTKSQektiykevIRVEKDPVLEGERARVWEILNRERAARKGREEDVRSLQERID 1595
Cdd:COG4717    347 EELQELLREAEELEE--ELQLEELEQEIAA--------LLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLG 416

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1596 RAEALRRSWSREEAElqrardqasqdcGRLQRQLRELEQQKQQKARQLQEEGRLlsqkteSERQKAAQRSQAVTQLEAAI 1675
Cdd:COG4717    417 ELEELLEALDEEELE------------EELEELEEELEELEEELEELREELAEL------EAELEQLEEDGELAELLQEL 478

                          490
                   ....*....|..
gi 1720364114 1676 LQEKDKIYEKER 1687
Cdd:COG4717    479 EELKAELRELAE 490
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1198-1396 8.15e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 8.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1198 ALARELQELQEKYRvvEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPV 1277
Cdd:COG4942     24 EAEAELEQLQQEIA--ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1278 V--EYKEVTQEVVRHEKNPEVL--------------------------REIDRLKAQLNELVNTNGRSQEQLIRLQGERD 1329
Cdd:COG4942    102 QkeELAELLRALYRLGRQPPLAlllspedfldavrrlqylkylaparrEQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720364114 1330 EWKRERSKVETKMVSKEVVRHEkdpvLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRP 1396
Cdd:COG4942    182 ELEEERAALEALKAERQKLLAR----LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 502-1053 1.01e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.62  E-value: 1.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  502 EAVAKASRLATELQTLKQKLSTEK---NRLKAAAVEHLQPGQQAPAGSAPADPQGQTLLSQMTQLDGDLGQIERQVLSWA 578
Cdd:COG1196    257 ELEAELAELEAELEELRLELEELElelEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  579 RSPLSQSSSLKDLEGRIHSCEGTAQRLQSLGAEKEAAQQECEAFLSTK------PTGSAALQLPVVLNSVKNRYNDVQSL 652
Cdd:COG1196    337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELaeelleALRAAAELAAQLEELEEAEEALLERL 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  653 CHLYGEKAKAALGLEKQIQEADRVIQGFEAALALEGPVPEGSGALQERVSELQRQRKELLQQQACVLGLHRQLKATEHAC 732
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  733 SALQNNFQEFCQD-LPRQQRQVRALTDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDNLSS------WLEQLPHHRVQ- 804
Cdd:COG1196    497 LEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVaaaaieYLKAAKAGRATf 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  805 ---PSDGPSQISYKLQAQKRLIQEILGREQDQATVSRLTRDLQEALQDYELQADTYRCSLEPALAVSAPKRLRVISLQES 881
Cdd:COG1196    577 lplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGG 656

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  882 IQAQEKNLAKAYTEVAAAEQQQLRQLEFAKKMLRKKELDEDIQAIHSARQgsgspahartAESEVLKTQLEEERKRVAEV 961
Cdd:COG1196    657 SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE----------RELAEAEEERLEEELEEEAL 726

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  962 QRDLEEQRQRLLQLRTQQPVARLEEKEVvefyrDPQLESNLSQAASRVEEEGKRRARLQA-------ELEAVAQKVVHLE 1034
Cdd:COG1196    727 EEQLEAEREELLEELLEEEELLEEEALE-----ELPEPPDLEELERELERLEREIEALGPvnllaieEYEELEERYDFLS 801

                          570
                   ....*....|....*....
gi 1720364114 1035 GKRKTmqphlLTKEVTQIE 1053
Cdd:COG1196    802 EQRED-----LEEARETLE 815
46 PHA02562
endonuclease subunit; Provisional
 863-1090 1.19e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.93  E-value: 1.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  863 PALAVSAPKRLRVIS--LQESIQAQEKNLAKAYTEVAAAEQQQL--------RQLEFAKK-MLRKKELDEDIQAIHSARQ 931
Cdd:PHA02562   143 PFMQLSAPARRKLVEdlLDISVLSEMDKLNKDKIRELNQQIQTLdmkidhiqQQIKTYNKnIEEQRKKNGENIARKQNKY 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  932 GSgspaHARTAESevLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQpvARLEEK-----EVVEFYRD----PQLESNL 1002
Cdd:PHA02562   223 DE----LVEEAKT--IKAEIEELTDELLNLVMDIEDPSAALNKLNTAA--AKIKSKieqfqKVIKMYEKggvcPTCTQQI 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1003 SQAASRVEEEGKRRARLQAELEAVAQKVVHLEGK-----RKTMQPHLLTKEVTQIERD-PGLDSQVTQLHSEMQRLRGEN 1076
Cdd:PHA02562   295 SEGPDRITKIKDKLKELQHSLEKLDTAIDELEEImdefnEQSKKLLELKNKISTNKQSlITLVDKAKKVKAAIEELQAEF 374

                          250
                   ....*....|....
gi 1720364114 1077 GVLTARLEELKDEL 1090
Cdd:PHA02562   375 VDNAEELAKLQDEL 388
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1178-1541 1.68e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1178 LLKEASRLRSLLEEEKNNNVALARELQELQEKYRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQEtgskKSGV 1257
Cdd:COG4717     93 LQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEE----LEEL 168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1258 EQEVEKLLPELEVLRAQKPVVEYKEVTQEVVRHEknpEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSK 1337
Cdd:COG4717    169 EAELAELQEELEELLEQLSLATEEELQDLAEELE---ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERL 245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1338 VETK--------MVSKEVVRHEKDPVLEKEAE------------RLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPE 1397
Cdd:COG4717    246 KEARlllliaaaLLALLGLGGSLLSLILTIAGvlflvlgllallFLLLAREKASLGKEAEELQALPALEELEEEELEELL 325

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1398 EQIVVQEVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQ 1477
Cdd:COG4717    326 AALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELE 405

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720364114 1478 ELEKRPPALQEKiiMEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQK 1541
Cdd:COG4717    406 ELEEQLEELLGE--LEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 952-1698 1.75e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.89  E-value: 1.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  952 EEERKRVAEVQRDLEEQRQRLLQLRTQQPVARLEEKEVVEFYRDPQLESNLSQAaSRVEEEGKRRARLQAELEAVAQKVV 1031
Cdd:TIGR00618  185 EFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQT-QQSHAYLTQKREAQEEQLKKQQLLK 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1032 HLEGKRKTMQPHLLTKEVTQIERDpgLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVK 1111
Cdd:TIGR00618  264 QLRARIEELRAQEAVLEETQERIN--RARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1112 VEKDLEMVKAAQTLRLQIE-EDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSllE 1190
Cdd:TIGR00618  342 EQRRLLQTLHSQEIHIRDAhEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSA--F 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1191 EEKNNNVALARELQELQEKYRVVEKQKPKVQLQERVSEIfqvlPETEQEIRRLRAQLQETGSKKSGVEQEVEKllpelev 1270
Cdd:TIGR00618  420 RDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEK----IHLQESAQSLKEREQQLQTKEQIHLQETRK------- 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1271 lraqkpvveYKEVTQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRH 1350
Cdd:TIGR00618  489 ---------KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRA 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1351 EkdpvLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRlsrSLDEEVG 1430
Cdd:TIGR00618  560 S----LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQ---DLQDVRL 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1431 RRRQLELEVRQLGARVEEEEARLSFEEDRsKKLAAERELRQLTLKIQELEkrPPALQEKIIMEEVVKlekdPDLERSTEA 1510
Cdd:TIGR00618  633 HLQQCSQELALKLTALHALQLTLTQERVR-EHALSIRVLPKELLASRQLA--LQKMQSEKEQLTYWK----EMLAQCQTL 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1511 LRRELDQEKnrvtELHRECQGLQVQVDLLQKTKSQEKTIYKEVIRvekdpvlEGERARVWEILNRERAARKGREEDVRSL 1590
Cdd:TIGR00618  706 LRELETHIE----EYDREFNEIENASSSLGSDLAAREDALNQSLK-------ELMHQARTVLKARTEAHFNNNEEVTAAL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1591 QERIDRAEAlrrswsreEAELQRARDQASQDcgrlQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVTQ 1670
Cdd:TIGR00618  775 QTGAELSHL--------AAEIQFFNRLREED----THLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSA 842

                          730       740
                   ....*....|....*....|....*...
gi 1720364114 1671 LEAAILQEKDKIYEKERTLRDLHTKVSR 1698
Cdd:TIGR00618  843 TLGEITHQLLKYEECSKQLAQLTQEQAK 870
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1503-1692 1.90e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.55  E-value: 1.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1503 DLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQkTKSQEKTIYKEVIRVEKDpvLEGERARVWEILNRERAARKG 1582
Cdd:COG3206    172 EARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVD-LSEEAKLLLQQLSELESQ--LAEARAELAEAEARLAALRAQ 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1583 REEDVRSLQERIdrAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAA 1662
Cdd:COG3206    249 LGSGPDALPELL--QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQ 326

                          170       180       190
                   ....*....|....*....|....*....|
gi 1720364114 1663 QRSQAVTQLEAAILQEKDKIYEKERTLRDL 1692
Cdd:COG3206    327 AREASLQAQLAQLEARLAELPELEAELRRL 356
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1431-1642 2.49e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 2.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1431 RRRQLELEVRQLGARVEEEEARLsfEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEvvklEKDPDLERSTEA 1510
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKEL--AALKKEEKALLKQLAALERRIAALARRIRALEQELAALE----AELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1511 LRRELDQEKNRVTELHRECQ--GLQVQVDLLQKTKSQEKTI-----YKEVIRVEKDPV---------LEGERARVWEILN 1574
Cdd:COG4942     95 LRAELEAQKEELAELLRALYrlGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAeelradlaeLAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720364114 1575 RERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQ 1642
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 699-1090 3.30e-04

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 45.95  E-value: 3.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  699 ERVSELQRQRKELLQQQACVLGLHRQLKATEHACSALQ-----NNFQEFCQDLPRQQRQVRALTDRYHAVgdqLDLREKI 773
Cdd:PRK10246   254 ELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPARQlrphwERIQEQSAALAHTRQQIEEVNTRLQST---MALRARI 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  774 VQDASLTYQQLRNSRDNLSSWLEQLPHHRVQPSDGP------SQISYKLQAQKRLIQEILGREQDQATVSRLTRDL--QE 845
Cdd:PRK10246   331 RHHAAKQSAELQAQQQSLNTWLAEHDRFRQWNNELAgwraqfSQQTSDREQLRQWQQQLTHAEQKLNALPAITLTLtaDE 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  846 ALQDYELQADtyrcslepalavSAPKRLRVISLQESIQAQEKNLAKAYTEVAAAEQQQLRqlefAKKMLRKKELDEDIQA 925
Cdd:PRK10246   411 VAAALAQHAE------------QRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQ----RNAALNEMRQRYKEKT 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  926 IHSARqgsgspahartaesevLKTQLEEErkrvaEVQRDLEEQRQRlLQLRTQQPVARLEEKEVVEFYRdpQLESNLSQA 1005
Cdd:PRK10246   475 QQLAD----------------VKTICEQE-----ARIKDLEAQRAQ-LQAGQPCPLCGSTSHPAVEAYQ--ALEPGVNQS 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1006 asrveeegkRRARLQAELEAVAQKVVHLEGKRKTMQphlltkevTQIERDpgldsqvtqlHSEMQRLRGENGVLTARLEE 1085
Cdd:PRK10246   531 ---------RLDALEKEVKKLGEEGAALRGQLDALT--------KQLQRD----------ESEAQSLRQEEQALTQQWQA 583


                   ....*
gi 1720364114 1086 LKDEL 1090
Cdd:PRK10246   584 VCASL 588
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 878-1466 4.52e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.34  E-value: 4.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  878 LQESIQAQEKNLAKAYTEVAAAEQQQLRQLEFAKKMLRKKELDEDIQAIHSARQG----------------------SGS 935
Cdd:TIGR00618  231 LREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERinrarkaaplaahikavtqieqQAQ 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  936 PAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQ---------QPVARLEEKEVVEFYRDP---------- 996
Cdd:TIGR00618  311 RIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQeihirdaheVATSIREISCQQHTLTQHihtlqqqktt 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  997 --QLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHLLTKEV-------TQIERDPGLDSQVTQLHS 1067
Cdd:TIGR00618  391 ltQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAaitctaqCEKLEKIHLQESAQSLKE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1068 EMQRLrGENGVLTARLEELKDELLA--LEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKETV-- 1143
Cdd:TIGR00618  471 REQQL-QTKEQIHLQETRKKAVVLArlLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVyh 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1144 -----AKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVALARELQELQEKYRVVEKQKP 1218
Cdd:TIGR00618  550 qltseRKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1219 KVQLQERVSEIFQV-----------LPETEQEIRRLRAQLQETGSKKSgVEQEVEKLLPELEVLRAQKPVVEYKevtQEV 1287
Cdd:TIGR00618  630 VRLHLQQCSQELALkltalhalqltLTQERVREHALSIRVLPKELLAS-RQLALQKMQSEKEQLTYWKEMLAQC---QTL 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1288 VRHEKnpEVLREIDRLKAQLNELVNTNGRS-QEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDPVLEKEAERLRQE 1366
Cdd:TIGR00618  706 LRELE--THIEEYDREFNEIENASSSLGSDlAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHL 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1367 VREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQK------DPKLREEHSRLS--RSLDEEVGRRRQLELE 1438
Cdd:TIGR00618  784 AAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVqeeeqfLSRLEEKSATLGeiTHQLLKYEECSKQLAQ 863

                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 1720364114 1439 VRQLGARVEEEEARL--------SFEEDRSKKLAAE 1466
Cdd:TIGR00618  864 LTQEQAKIIQLSDKLnginqikiQFDGDALIKFLHE 899
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 817-1029 4.53e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 4.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  817 QAQKRLIQEILGREQDQATVSRLTRDLQEALQDYELQADTYRCSLEPALAVSAPKRLRVISLQESIQAQEKNLAKAYTEV 896
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  897 AA--AEQQQLRQLEFAKKMLRKKELDEDI------QAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQ 968
Cdd:COG4942    107 AEllRALYRLGRQPPLALLLSPEDFLDAVrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEE 186

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720364114  969 RQRLLQLRTQQpvarleeKEVVEfyrdpQLESNLSQAASRVEEEGKRRARLQAELEAVAQK 1029
Cdd:COG4942    187 RAALEALKAER-------QKLLA-----RLEKELAELAAELAELQQEAEELEALIARLEAE 235
Plectin pfam00681
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ...
 1718-1746 5.62e-04

Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.


Pssm-ID: 459901  Cd Length: 39  Bit Score: 39.23  E-value: 5.62e-04
                           10        20
                   ....*....|....*....|....*....
gi 1720364114 1718 ILEPETGNDMSPYEAYKRGVIDRGQYLQL 1746
Cdd:pfam00681   11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
823-1097 7.85e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 7.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  823 IQEILGREQDQATVSRLtrDLQEALQDYELQADTYRCSLEPALAVSAPKRLRVISLqeSIQAQEKNLAK----AYTEVAA 898
Cdd:COG3206     87 IEILKSRPVLERVVDKL--NLDEDPLGEEASREAAIERLRKNLTVEPVKGSNVIEI--SYTSPDPELAAavanALAEAYL 162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  899 AEQQQLRQ------LEFAKKMLR--KKELDEDIQAIHSARQGSGSPAHARTAESEVlkTQLEEERKRVAEVQRDLEEQRQ 970
Cdd:COG3206    163 EQNLELRReearkaLEFLEEQLPelRKELEEAEAALEEFRQKNGLVDLSEEAKLLL--QQLSELESQLAEARAELAEAEA 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  971 RLLQLRTQQPVARLEEKEVVEFYRDPQLESNLSQAASrveeegkRRARLQAELEAVAQKVVHLEGKRKTMQPhLLTKEVT 1050
Cdd:COG3206    241 RLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEA-------ELAELSARYTPNHPDVIALRAQIAALRA-QLQQEAQ 312

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1720364114 1051 QIerdpgldsqVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKE 1097
Cdd:COG3206    313 RI---------LASLEAELEALQAREASLQAQLAQLEARLAELPELE 350
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1324-1679 7.98e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.50  E-value: 7.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1324 LQGERDEWKRERSKVETKMVSKEVVRHEKDPVLEKEAERLRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQ 1403
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1404 EvvvtqkdpkLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERelrqltlKIQELEKRp 1483
Cdd:pfam07888  112 E---------LSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQR-------KEEEAERK- 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1484 pALQEKiimeevvklekdpdLERSTEALRR---ELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEktiykevirvekdp 1560
Cdd:pfam07888  175 -QLQAK--------------LQQTEEELRSlskEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTA-------------- 225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1561 vlegerarvweilNRERAARKGREEDVRSLQERID----RAEALRRSWS-------REEAELQRARDQASQdcgrLQRQL 1629
Cdd:pfam07888  226 -------------HRKEAENEALLEELRSLQERLNaserKVEGLGEELSsmaaqrdRTQAELHQARLQAAQ----LTLQL 288

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1630 RELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVTQLEAAILQEK 1679
Cdd:pfam07888  289 ADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEER 338
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1120-1509 8.59e-04

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 44.18  E-value: 8.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1120 KAAQTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVAL 1199
Cdd:COG5185    208 KESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNL 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1200 ARELQELQEKYRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKpvve 1279
Cdd:COG5185    288 IKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEI---- 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1280 ykevtQEVVRHEKNPEVLREIDRLKAQLNELVntngrsqeqlirlqgERDEWKRERSKVETKMVSKEVVRHEKdpVLEKE 1359
Cdd:COG5185    364 -----ENIVGEVELSKSSEELDSFKDTIESTK---------------ESLDEIPQNQRGYAQEILATLEDTLK--AADRQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1360 AERLRQEVREAVQRrratedaVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLELEV 1439
Cdd:COG5185    422 IEELQRQIEQATSS-------NEEVSKLLNELISELNKVMREADEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRV 494

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720364114 1440 RQLGARVEEEEARLsfeedrSKKLAAER-ELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTE 1509
Cdd:COG5185    495 STLKATLEKLRAKL------ERQLEGVRsKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNAKTD 559
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 877-1095 8.61e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  877 SLQESIQAQEKNLAKAYTEVAAAeQQQLRQLEfakkmlrkKELDEDIQAIHSARQgsgspahartaESEVLKTQLEEERK 956
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKAL-LKQLAALE--------RRIAALARRIRALEQ-----------ELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  957 RVAEVQRDLEEQRQRL-LQLRTQQPVARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRAR-LQAELEAVAQKVVHLE 1034
Cdd:COG4942     91 EIAELRAELEAQKEELaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEeLRADLAELAALRAELE 170

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720364114 1035 GKRKTMQpHLLTKEVTQIERdpgLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQ 1095
Cdd:COG4942    171 AERAELE-ALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 900-1253 9.08e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 44.34  E-value: 9.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  900 EQQQLRQL--EFAKKMLRKKELDEDiqaiHSARQGSGSPAHARTAESEvlktQLEEERKRvaEVQRDLEEQRQRLLQLRT 977
Cdd:pfam17380  297 EQERLRQEkeEKAREVERRRKLEEA----EKARQAEMDRQAAIYAEQE----RMAMERER--ELERIRQEERKRELERIR 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  978 QQPVArleekevVEFYRDPQLEsnlsqaasRVEEEGKRR-ARLQAELEAVAQKVVHLEGKRKTMQPHLLTKEVTQIERDP 1056
Cdd:pfam17380  367 QEEIA-------MEISRMRELE--------RLQMERQQKnERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEE 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1057 GLDSQVTQLHSE----MQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQTLRLQIEED 1132
Cdd:pfam17380  432 ARQREVRRLEEErareMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEE 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1133 AARRKGAKETVAKIQARIKDLEQaissvepkvivkevkkveqdpgllkeasrlRSLLEEEKNNNVALaRELQELQEKYRV 1212
Cdd:pfam17380  512 ERKRKLLEKEMEERQKAIYEEER------------------------------RREAEEERRKQQEM-EERRRIQEQMRK 560

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 1720364114 1213 VEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSK 1253
Cdd:pfam17380  561 ATEERSRLEAMEREREMMRQIVESEKARAEYEATTPITTIK 601
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1465-1674 9.83e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 9.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1465 AERELRQLTLKIQELEKRPPALQEKIImeevvklekdpDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKS 1544
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELD-----------ALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1545 QEKTIYKEVIRVEK---------DPVLEGE-------RARVW--------EILNRERAARKGREEDVRSLQERIDRAEAL 1600
Cdd:COG3883     83 ERREELGERARALYrsggsvsylDVLLGSEsfsdfldRLSALskiadadaDLLEELKADKAELEAKKAELEAKLAELEAL 162

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720364114 1601 RRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVTQLEAA 1674
Cdd:COG3883    163 KAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 879-1259 1.01e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.19  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  879 QESIQAQEKNLAKAYtEVAAAEQQQLRQLEFAKKMLRKKELDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRV 958
Cdd:pfam02463  679 QELQEKAESELAKEE-ILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRL 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  959 aEVQRDLEEQRQRLLQLRTQQPVARLEEKEVVEfyrdpQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRK 1038
Cdd:pfam02463  758 -KKEEKEEEKSELSLKEKELAEEREKTEKLKVE-----EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1039 TMQPHLLTKEVTQIERDPGLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVekdlem 1118
Cdd:pfam02463  832 EEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEE------ 905

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1119 vkaaqTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEKNNNVA 1198
Cdd:pfam02463  906 -----SQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAI 980

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720364114 1199 LARELQELQEKYRVVEKQKPKvqlQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQ 1259
Cdd:pfam02463  981 EEFEEKEERYNKDELEKERLE---EEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFF 1038
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 895-1546 1.09e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.34  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  895 EVAAAEQQQLRQLEFAKKMLRKKEL--DEDIQAIHSARQGSGSPAHARTAESEVLKTQlEEERKRVAEVQRDLEEQRQRL 972
Cdd:pfam15921  248 EALKSESQNKIELLLQQHQDRIEQLisEHEVEITGLTEKASSARSQANSIQSQLEIIQ-EQARNQNSMYMRQLSDLESTV 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  973 LQLRTqqpvarlEEKEVVEFYRDP--QLESNLSQAASRVEEEGKRRARLQAE---LEAVAQKVV-HLEGKRKTMQphlLT 1046
Cdd:pfam15921  327 SQLRS-------ELREAKRMYEDKieELEKQLVLANSELTEARTERDQFSQEsgnLDDQLQKLLaDLHKREKELS---LE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1047 KEVTQ--IERDPGLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKVVVKEVVKVEKDLEMVKAAQT 1124
Cdd:pfam15921  397 KEQNKrlWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1125 LRLQIEEDAARR---KGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQdpglLKEASRLRSllEEEKNNNVALAR 1201
Cdd:pfam15921  477 LRKVVEELTAKKmtlESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLK----LQELQHLKN--EGDHLRNVQTEC 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1202 ELQELQ--EKYRVVE----------------------KQKPKVQLQERVSEI------FQVLPET-EQEIRRLRAQLQE- 1249
Cdd:pfam15921  551 EALKLQmaEKDKVIEilrqqienmtqlvgqhgrtagaMQVEKAQLEKEINDRrlelqeFKILKDKkDAKIRELEARVSDl 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1250 ---------TGSKK----SGVEQEVEKLLPELEVLRAQ-KPVVEYKEVTQEVVRHeKNPEVLREIDRLKAQL-------- 1307
Cdd:pfam15921  631 elekvklvnAGSERlravKDIKQERDQLLNEVKTSRNElNSLSEDYEVLKRNFRN-KSEEMETTTNKLKMQLksaqsele 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1308 ---NELVNTNGRS----------QEQLIRLQGERDEWKRERSKVETKMVSKEVVRHekdpVLEKEAERLRQEVREAvqrr 1374
Cdd:pfam15921  710 qtrNTLKSMEGSDghamkvamgmQKQITAKRGQIDALQSKIQFLEEAMTNANKEKH----FLKEEKNKLSQELSTV---- 781

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1375 rATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLELEVRQLG----------- 1443
Cdd:pfam15921  782 -ATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQgpgytsnssmk 860

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1444 -------------ARVEEEEARLSFEEDRSKKLAAERE--LRQLTLKIQElekrppaLQEKIIMEEVVKLEKDPDLERST 1508
Cdd:pfam15921  861 prllqpasftrthSNVPSSQSTASFLSHHSRKTNALKEdpTRDLKQLLQE-------LRSVINEEPTVQLSKAEDKGRAP 933

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 1720364114 1509 EALRRElDQEKNRVTEL-------HRECQGLQVQVDLLQKTKSQE 1546
Cdd:pfam15921  934 SLGALD-DRVRDCIIESslrsdicHSSSNSLQTEGSKSSETCSRE 977
SPEC smart00150
Spectrin repeats;
302-359 1.14e-03

Spectrin repeats;


Pssm-ID: 197544 [Multi-domain]  Cd Length: 101  Bit Score: 40.39  E-value: 1.14e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720364114   302 QHELLAQERSINQLEDDADRMVELGHPAIGPIQVHQEALKMEWQNFLNLCICQESQLQ 359
Cdd:smart00150   44 EAELEAHEERVEALNELGEQLIEEGHPDAEEIEERLEELNERWEELKELAEERRQKLE 101
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 658-1299 1.16e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.94  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  658 EKAKAALGLEKQIQEADRVIQGFEAALALEGPVPEGSGALQERVSELQRQRKEL----------------------LQQQ 715
Cdd:pfam05483  128 ENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETrqvymdlnnniekmilafeelrVQAE 207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  716 ACVLGLHRQLKATEHACSALQnnfQEFCQDLPRQQRQVRAL----TDRYHAVGDQLDLREKIVQDASLTYQQLRNSRDNL 791
Cdd:pfam05483  208 NARLEMHFKLKEDHEKIQHLE---EEYKKEINDKEKQVSLLliqiTEKENKMKDLTFLLEESRDKANQLEEKTKLQDENL 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  792 SSWLEQLPHHRVQPSDGPSQISYKLQAQKRLIQEIlgrEQDQATVSRLTRDLQEALQDY------------ELQADTyrC 859
Cdd:pfam05483  285 KELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDL---QIATKTICQLTEEKEAQMEELnkakaahsfvvtEFEATT--C 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  860 SLEPALAVSAPK------RLRVISLQESIQAQEKNLAKAYTEVAAAEQQQLR-------QLEFAKKMLRK--KELDEDIQ 924
Cdd:pfam05483  360 SLEELLRTEQQRleknedQLKIITMELQKKSSELEEMTKFKNNKEVELEELKkilaedeKLLDEKKQFEKiaEELKGKEQ 439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  925 AIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQPVARLEEKEVVEFYRDPQLEsnLSQ 1004
Cdd:pfam05483  440 ELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLE--LKK 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1005 AASRVEEEGKRRARLQAELEAVAQKVVHLEGKRKTMQPHLLTKEVTQIERDPGLDSQVTQLHSEMQRLRGENGVLTARLE 1084
Cdd:pfam05483  518 HQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCN 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1085 ELKDEllaLEQKEMNVKekvvvkevvkvekdlemvkaaqtlRLQIEEDAARRKGAKET---------VAKIQARIKDLEQ 1155
Cdd:pfam05483  598 NLKKQ---IENKNKNIE------------------------ELHQENKALKKKGSAENkqlnayeikVNKLELELASAKQ 650

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1156 AISSVEPKVIVKEVKKVEQDPGLLKEASRLRSLLEEEknnnVALARELqELQEKYRVVEkqkpKVQLQERVSEIF-QVLP 1234
Cdd:pfam05483  651 KFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEA----VKLQKEI-DKRCQHKIAE----MVALMEKHKHQYdKIIE 721

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720364114 1235 ETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKPvVEYKEVTQEVVRHEKNPEVLRE 1299
Cdd:pfam05483  722 ERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLE-IEKEEKEKLKMEAKENTAILKD 785
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1413-1609 1.21e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1413 KLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLaaERELRQLTLKIQELEKRPPALQEKII- 1491
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAAL--EAELAELEKEIAELRAELEAQKEELAe 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1492 -------------MEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIRVEK 1558
Cdd:COG4942    109 llralyrlgrqppLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA 188

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1720364114 1559 D-PVLEGERARVWEILNRERAARKGR----EEDVRSLQERIDRAEALRRSWSREEA 1609
Cdd:COG4942    189 AlEALKAERQKLLARLEKELAELAAElaelQQEAEELEALIARLEAEAAAAAERTP 244
PLEC smart00250
Plectin repeat;
1850-1885 1.25e-03

Plectin repeat;


Pssm-ID: 197605  Cd Length: 38  Bit Score: 38.23  E-value: 1.25e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1720364114  1850 LTEDSFPIAGIYDTTTDNKCSIKAAVAKNMLDPITG 1885
Cdd:smart00250    3 LLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
1297-1713 1.49e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 43.36  E-value: 1.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1297 LREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVeTKMVSKEVVRHEKDPVLEKEAERLRQEVREAVQRRRA 1376
Cdd:COG5278     85 RAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQV-IALRRAGGLEAALALVRSGEGKALMDEIRARLLLLAL 163

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1377 TEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDPKLREEHSRLSRSLDEEVGRRRQLELEVRQLGARVEEEEARLSFE 1456
Cdd:COG5278    164 ALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALA 243

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1457 EDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQV 1536
Cdd:COG5278    244 LLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAA 323

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1537 DLLQKTKSQEKTIYKEVIRVEKDPVLEGERARvwEILNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARD 1616
Cdd:COG5278    324 ALAALLALALATALAAAAAALALLAALLAEAA--AAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAA 401

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1617 QASQDCGRLQRQLRELEQQKQQKARQLQEEGRLLSQKTESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKV 1696
Cdd:COG5278    402 AAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAA 481

                          410
                   ....*....|....*..
gi 1720364114 1697 SREELNQETQTRETNLS 1713
Cdd:COG5278    482 AALAEAEAAAALAAAAA 498
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 502-1098 1.90e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  502 EAVAKASRLATELQTLKQKLSTEKNRLKAAAVEHLQPGQQAPAGSAPADP--QGQTLLSQMTQLDGDLGQIERQVLSWAR 579
Cdd:TIGR00618  331 AAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHihTLQQQKTTLTQKLQSLCKELDILQREQA 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  580 SPLSQSSSLKDLEGRIHSCEGTAQRLQSLGAEKEAAQQEceAFLSTKPTGSAALQLPVVLNSVKNRYNDVQSLCHLYGEK 659
Cdd:TIGR00618  411 TIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITC--TAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRK 488

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  660 AKAALGLEKQIQEADRVIQGFEAALALEGPVPEGSGALQERVSELQRQRKELLQQqacvlglhrqLKATEHACSALQNNF 739
Cdd:TIGR00618  489 KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETS----------EEDVYHQLTSERKQR 558

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  740 QEFCQDLPRQQRQVRALTDRYHAVGDQLDLREKIVQDasltyqqlrnsrdnLSSWLEQLPHHRVQpsdgpsqisyklqaq 819
Cdd:TIGR00618  559 ASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVR--------------LQDLTEKLSEAEDM--------------- 609

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  820 KRLIQEILGREqdqatvsrltrdLQEALQDYELQADTYRCSLEPALAVSAPKRLRVISLQE-------SIQAQEKNLAKA 892
Cdd:TIGR00618  610 LACEQHALLRK------------LQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQErvrehalSIRVLPKELLAS 677

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  893 YTEVAAAEQQQLRQLEFAKKMLRKKelDEDIQAIHSARQGSGSPAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRL 972
Cdd:TIGR00618  678 RQLALQKMQSEKEQLTYWKEMLAQC--QTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTV 755

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  973 LQLRTQQPvARLEEKEVVEFYRDPQLESNLSQAASRVEEEGKRRARLQAELEAVAQKVVHLEGKRkTMQPHLLTKEVTQi 1052
Cdd:TIGR00618  756 LKARTEAH-FNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDIL-NLQCETLVQEEEQ- 832

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1720364114 1053 erdpgLDSQVTQLHSEMQRLRGENGVLTARLEELkdELLALEQKEM 1098
Cdd:TIGR00618  833 -----FLSRLEEKSATLGEITHQLLKYEECSKQL--AQLTQEQAKI 871
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1576-1716 2.12e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1576 ERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRARDQASQdcgrLQRQLRELEQQKQQKARQLQEEGRLLSQKTE 1655
Cdd:COG1196    213 ERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEE----LEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720364114 1656 SERQKAAQRSQAvtqleaailqEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLSTKI 1716
Cdd:COG1196    289 EEYELLAELARL----------EQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1123-1334 2.21e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1123 QTLRLQIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPG---LLKEASRLRSLLEEEKNNNVAL 1199
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElaeLEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1200 ARELQEL--QEKYRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAQKpv 1277
Cdd:COG4942    110 LRALYRLgrQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER-- 187

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720364114 1278 veyKEVTQEVVRHEKNPEVL-REIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRE 1334
Cdd:COG4942    188 ---AALEALKAERQKLLARLeKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1325-1693 2.27e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.40  E-value: 2.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1325 QGERDEWKRERSKVeTKMVSKEVVRH--EKDPVLEKEAErLRQEVREAVQRRRATEDAVYELQNKLLLLERRRpeeqivv 1402
Cdd:COG3096    252 QSDRDLFKHLITEA-TNYVAADYMRHanERRELSERALE-LRRELFGARRQLAEEQYRLVEMARELEELSARE------- 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1403 qevVVTQKDPKLREEHSRLSRS---LDEEVGRRRQlelEVRQLGARVEE-----EEARLSFEEDRSKKLAAERELRQLTL 1474
Cdd:COG3096    323 ---SDLEQDYQAASDHLNLVQTalrQQEKIERYQE---DLEELTERLEEqeevvEEAAEQLAEAEARLEAAEEEVDSLKS 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1475 KIQELEKRPPALQEKII--------MEEVVKLEKDPDLerSTEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQE 1546
Cdd:COG3096    397 QLADYQQALDVQQTRAIqyqqavqaLEKARALCGLPDL--TPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQF 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1547 KTIY-------------------KEVIR--------VEKDPVLEGERARVWEILNRERAARKGREEDVRSLQERIDRAEA 1599
Cdd:COG3096    475 EKAYelvckiageversqawqtaRELLRryrsqqalAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEE 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1600 LRRSWSREEAELQRARDQAS---QDCGRLQRQLRELEQQK-------------QQKARQLQEE-GRLL--SQKTESERQK 1660
Cdd:COG3096    555 LEELLAELEAQLEELEEQAAeavEQRSELRQQLEQLRARIkelaarapawlaaQDALERLREQsGEALadSQEVTAAMQQ 634

                          410       420       430
                   ....*....|....*....|....*....|...
gi 1720364114 1661 AAQRSQAVTQLEAAILQEKDKIyekERTLRDLH 1693
Cdd:COG3096    635 LLEREREATVERDELAARKQAL---ESQIERLS 664
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 1183-1563 2.60e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 42.69  E-value: 2.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1183 SRLRSLLEEEKN-NNVALARELQELQEKY---RVVEKQKPKVQLQERV-SEIFQVLPETEQEIRRLRAQLQETGSKksgV 1257
Cdd:NF033838    72 SEIQKSLDKRKHtQNVALNKKLSDIKTEYlyeLNVLKEKSEAELTSKTkKELDAAFEQFKKDTLEPGKKVAEATKK---V 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1258 EQEVEKLLPELEVLRAQKPVVEYKevTQEVVRHEKNPEVLR-EIDRLKAQLNElvntngrsqeqlirlqgERDEWKRERS 1336
Cdd:NF033838   149 EEAEKKAKDQKEEDRRNYPTNTYK--TLELEIAESDVEVKKaELELVKEEAKE-----------------PRDEEKIKQA 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1337 KVETKMVSKEVVRHEKDPVLEKEAERLRQEVREAVQRRRATEDAVYELQNKLllleRRRPEEQIVVQEVVVTQKDPKLRE 1416
Cdd:NF033838   210 KAKVESKKAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKP----KRRAKRGVLGEPATPDKKENDAKS 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1417 EHSrlsrSLDEEVGRRRQLELEVRQLGA--RVEEEE--ARLSFEEDRskklaaeRELRQLTLKIQELEkrppalqekiIM 1492
Cdd:NF033838   286 SDS----SVGEETLPSPSLKPEKKVAEAekKVEEAKkkAKDQKEEDR-------RNYPTNTYKTLELE----------IA 344

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720364114 1493 EEVVKLeKDPDLERSTEALRRELDQEKnrVTELHRECQGLQVQVDLLQKTKSQEKTIYKEVIR--VEKDPVLE 1563
Cdd:NF033838   345 ESDVKV-KEAELELVKEEAKEPRNEEK--IKQAKAKVESKKAEATRLEKIKTDRKKAEEEAKRkaAEEDKVKE 414
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 947-1369 2.78e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.70  E-value: 2.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  947 LKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQqpVARLEeKEVVEfyrdpqLESNLSQAASRVEEEGKRRARLQAELEAV 1026
Cdd:TIGR04523  312 LKSELKNQEKKLEEIQNQISQNNKIISQLNEQ--ISQLK-KELTN------SESENSEKQRELEEKQNEIEKLKKENQSY 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1027 AQKVVHLEGKRKTMQPHLLTKEVTQIERD---PGLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEK 1103
Cdd:TIGR04523  383 KQEIKNLESQINDLESKIQNQEKLNQQKDeqiKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNT 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1104 VVVKEVVKVEKDLEMVKAAQTLRL---QIEEDAARRKGAKETVAKIQARIKDLEQAISSVEPKVIVKEVKKVEQDPGLLK 1180
Cdd:TIGR04523  463 RESLETQLKVLSRSINKIKQNLEQkqkELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISD 542

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1181 EASRLRSLLEEEKNNNvaLARELQELQEKyrVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQE 1260
Cdd:TIGR04523  543 LEDELNKDDFELKKEN--LEKEIDEKNKE--IEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1261 VEKLLPELEVLRAQKPVVEY-KEVTQEVVRHEKNPevlreIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVE 1339
Cdd:TIGR04523  619 LEKAKKENEKLSSIIKNIKSkKNKLKQEVKQIKET-----IKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHY 693

                          410       420       430
                   ....*....|....*....|....*....|
gi 1720364114 1340 TKMVsKEVVRHEKDPVLEKEAERLRQEVRE 1369
Cdd:TIGR04523  694 KKYI-TRMIRIKDLPKLEEKYKEIEKELKK 722
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1585-1700 4.14e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.38  E-value: 4.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1585 EDVRSLQERIDRAEalrrswsREEAELQRARDQASQD-CGRLQRQLRELEQQKQQKARQLQEEgRLLSQKTESERQKAAQ 1663
Cdd:COG0542    411 EELDELERRLEQLE-------IEKEALKKEQDEASFErLAELRDELAELEEELEALKARWEAE-KELIEEIQELKEELEQ 482

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1720364114 1664 RSQAVTQLEAAILQEKDKIYEKERTLRdlhTKVSREE 1700
Cdd:COG0542    483 RYGKIPELEKELAELEEELAELAPLLR---EEVTEED 516
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1212-1395 4.22e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 4.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1212 VVEKQKPKVQLQERVSEIFQVlpetEQEIRRLRAQLQEtgskksgVEQEVEKLLPELEVLRAqkpvvEYKEVTQEVVRHE 1291
Cdd:COG1579      2 MPEDLRALLDLQELDSELDRL----EHRLKELPAELAE-------LEDELAALEARLEAAKT-----ELEDLEKEIKRLE 65

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1292 KNPEVLRE-IDRLKAQLNelvntNGRSQEQLIRLQGERDEWKRERSKVETKMVSKEVVRHEKDPVLEKEAERLRQEVREA 1370
Cdd:COG1579     66 LEIEEVEArIKKYEEQLG-----NVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAEL 140

                          170       180
                   ....*....|....*....|....*
gi 1720364114 1371 VQRRRATEDAVYELQNKLLLLERRR 1395
Cdd:COG1579    141 EEKKAELDEELAELEAELEELEAER 165
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
950-1151 5.36e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 5.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  950 QLEEERKRVAEVQRDLEEQRQRLLQLRTQ--QPVARLEEKEVVEFYRDPQLesNLSQAASRVEEEGKRRARLQA---ELE 1024
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAEldALQERREALQRLAEYSWDEI--DVASAEREIAELEAELERLDAssdDLA 688

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1025 AVAQKVVHLEGKRKTmqphlltkevtqierdpgLDSQVTQLHSEMQRLRGENGVLTARLEELKDELLALEQKEMNVKEKV 1104
Cdd:COG4913    689 ALEEQLEELEAELEE------------------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL 750

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1720364114 1105 VVKEVVKVEKDLEMVKAAQTLRLQIEEDAARRKGAKETVAKIQARIK 1151
Cdd:COG4913    751 LEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFN 797
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1489-1716 5.49e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.88  E-value: 5.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1489 KIIMEEVVKLEKDPDLERSTEALRRELDQEKNRVTELHRECQGLQVQVD-----LLQKTKSQEKTIYKEVIRVEKDPVLE 1563
Cdd:pfam02463  156 LEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEqakkaLEYYQLKEKLELEEEYLLYLDYLKLN 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1564 GERARVWEILNRERAARKGREEDVRSL-QERIDRAEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKARQ 1642
Cdd:pfam02463  236 EERIDLLQELLRDEQEEIESSKQEIEKeEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEK 315

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720364114 1643 L---QEEGRLLSQKTESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQETQTRETNLSTKI 1716
Cdd:pfam02463  316 LkesEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKL 392
PRK12472 PRK12472
hypothetical protein; Provisional
 1596-1674 6.02e-03

hypothetical protein; Provisional


Pssm-ID: 237110 [Multi-domain]  Cd Length: 508  Bit Score: 41.39  E-value: 6.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1596 RAEALRRSwsREEA-----ELQRARDQASQDCGRLQRQLRELEQQKQQKARQLQEEGR-LLSQKT-------ESERQKAA 1662
Cdd:PRK12472   191 RAETLARE--AEDAaraadEAKTAAAAAAREAAPLKASLRKLERAKARADAELKRADKaLAAAKTdeakaraEERQQKAA 268

                           90
                   ....*....|...
gi 1720364114 1663 QR-SQAVTQLEAA 1674
Cdd:PRK12472   269 QQaAEAATQLDTA 281
RGS_LARG cd08754
Regulator of G protein signaling (RGS) domain found in the leukemia-associated Rho guanine ...
 609-744 6.31e-03

Regulator of G protein signaling (RGS) domain found in the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF) protein (LARG); The RGS domain is an essential part of the leukemia-associated RhoGEF protein (LARG), a member of the RhoGEF (Rho guanine nucleotide exchange factor) subfamily of the RGS protein family. The RhoGEFs are peripheral membrane proteins that regulate essential cellular processes, including cell shape, cell migration, cell cycle progression of cells, and gene transcription by linking signals from heterotrimeric G-alpha12/13 protein-coupled receptors to Rho GTPase activation, leading to various cellular responses, such as actin reorganization and gene expression. The RhoGEF subfamily includes p115RhoGEF, LARG, PDZ-RhoGEF, and its rat specific splice variant GTRAP48. The RGS domain of RhoGEFs has very little sequence similarity with the canonical RGS domain of the RGS proteins and is often refered to as RH (RGS Homology) domain. In addition to being a G-alpha13 effector, the LARG protein also functions as a GTPase-activating protein (GAP) for G-alpha13. RGS proteins play critical regulatory role as GTPase activating proteins (GAPs) of the heterotrimeric G-protein G-alpha-subunits. RGS proteins play critical regulatory role as GTPase activating proteins (GAPs) of the heterotrimeric G-protein G-alpha-subunits. RGS proteins regulate many aspects of embryonic development such as glial differentiation, embryonic axis formation, skeletal and muscle development, cell migration during early embryogenesis, as well as apoptosis, cell proliferation, and modulation of cardiac development.


Pssm-ID: 188708  Cd Length: 222  Bit Score: 40.36  E-value: 6.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  609 GAEKEAAQQECEAFLSTKPTGSAALQLPVVLNSVKNRYNDVQSLCHLYGEKAKaalglEKQIQEADRVIQGF-----EAA 683
Cdd:cd08754     11 PTESEQINGQCSCFQNIELLKSRPAHLAVFLHHVVSQFDPAALLCYLYADLYK-----QTNSKETRRVFLEFnqfflDRA 85

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720364114  684 LALEGPVPEgsgalqERVSELQRQRKELLQQQacvlgLHRQLKAT--EHACSALQNNFQEFCQ 744
Cdd:cd08754     86 ANLKVPVPD------EVSLDLEKRRPELIPEE-----LHRHYIQTmqERVSPEVQRNLEDFRQ 137
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1203-1359 6.61e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 6.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1203 LQELQEKYRVVEKQKPKVQLQERVSEifqvLPETEQEIRRLRAQLQETGSKKSGVEQEVEKLLPELEVLRAqkpvvEYKE 1282
Cdd:COG2433    382 LEELIEKELPEEEPEAEREKEHEERE----LTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLER-----ELSE 452

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1283 VTQEVVR-HEKNPEVL---REIDRLKAQLNELVNTNGRSQEQLIRLqgeRDEWKRERS--KVETKMV---SKEVVRHEKD 1353
Cdd:COG2433    453 ARSEERReIRKDREISrldREIERLERELEEERERIEELKRKLERL---KELWKLEHSgeLVPVKVVekfTKEAIRRLEE 529


                   ....*.
gi 1720364114 1354 PVLEKE 1359
Cdd:COG2433    530 EYGLKE 535
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 1568-1706 6.63e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 41.53  E-value: 6.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1568 RVWEILNRERAARKGREEDVRSLQERIDRAEALRRSWSREEAELQRAR-DQASQDCGRLQRQL---RELEQQKQQKAR-- 1641
Cdd:pfam05262  181 KVVEALREDNEKGVNFRRDMTDLKERESQEDAKRAQQLKEELDKKQIDaDKAQQKADFAQDNAdkqRDEVRQKQQEAKnl 260

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720364114 1642 -------------QLQEEGRLLSQKTESERQKAAQRSQAVTQLEAAILQEKDKIYEKERTLRDLHTKVSREELNQETQ 1706
Cdd:pfam05262  261 pkpadtsspkedkQVAENQKREIEKAQIEIKKNDEEALKAKDHKAFDLKQESKASEKEAEDKELEAQKKREPVAEDLQ 338
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1438-1748 6.73e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 6.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1438 EVRQLGARVEEEEARLSFEED-------RSKKLAAERELRQLTLKIQELEKRPPALQEKIimeEVVKLEKDPDLE----- 1505
Cdd:pfam15921  188 EIRSILVDFEEASGKKIYEHDsmstmhfRSLGSAISKILRELDTEISYLKGRIFPVEDQL---EALKSESQNKIElllqq 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1506 --RSTEALRRELDQEKNRVTE----LHRECQGLQVQVDLLQKTKSQEKTIYKEVirvekdpvLEGERARVWEILNRERAA 1579
Cdd:pfam15921  265 hqDRIEQLISEHEVEITGLTEkassARSQANSIQSQLEIIQEQARNQNSMYMRQ--------LSDLESTVSQLRSELREA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1580 RKGREEDVRSLQERIDRAEAlrrswsrEEAELQRARDQASQDCGRLQRQLREL--EQQKQQKARQLQEE--GRLLSQKTE 1655
Cdd:pfam15921  337 KRMYEDKIEELEKQLVLANS-------ELTEARTERDQFSQESGNLDDQLQKLlaDLHKREKELSLEKEqnKRLWDRDTG 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1656 SE------RQKAAQRSQAVTQLEAAILQEKDKIY-EKERTLRDLHTK-VSREELNQETQTRETNLSTKICILEPETGNDM 1727
Cdd:pfam15921  410 NSitidhlRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKnESLEKVSSLTAQLESTKEMLRKVVEELTAKKM 489

                          330       340
                   ....*....|....*....|.
gi 1720364114 1728 SpYEAYKRGVIDRGQYLQLQE 1748
Cdd:pfam15921  490 T-LESSERTVSDLTASLQEKE 509
Caldesmon pfam02029
Caldesmon;
1357-1669 7.07e-03

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 41.39  E-value: 7.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1357 EKEAER-LRQEVREAVQRRRATEDAVYELQNKLLLLERRRPEEQIVVQEVVVTQKDP--------KLREEhsRLSRSLDE 1427
Cdd:pfam02029    4 EEEAAReRRRRAREERRRQKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEeeafldrtAKREE--RRQKRLQE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1428 EVGRRRQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKIQELEKRPPALQEKIIMEEVVKLEKDPDLERS 1507
Cdd:pfam02029   82 ALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEEEGEEEED 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1508 TEALRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQEKTIYKEViRVEKDPVLEGERARVWEILNRERAARKGREEDV 1587
Cdd:pfam02029  162 KSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEV-KSQNGEEEVTKLKVTTKRRQGGLSQSQEREEEA 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1588 RSLQERIDRAEALRRSWS---REEAELQRARDQ-ASQDCGRL------QRQLRELEQQKQQKARQLQ-----EEGRLLSQ 1652
Cdd:pfam02029  241 EVFLEAEQKLEELRRRRQekeSEEFEKLRQKQQeAELELEELkkkreeRRKLLEEEEQRRKQEEAERklreeEEKRRMKE 320

                          330
                   ....*....|....*..
gi 1720364114 1653 KTESERQKAAQRSQAVT 1669
Cdd:pfam02029  321 EIERRRAEAAEKRQKLP 337
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1181-1394 8.97e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 8.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1181 EASRLRSLLEEEKNNnvaLARELQELQEKYRVVEKQKPKVQLQERVSEIFQVLPETEQEIRRLRAQLQETGSKKSGVEQE 1260
Cdd:COG3206    172 EARKALEFLEEQLPE---LRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQ 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1261 VEKLLPELevlraqkpvveykevtQEVVRHEKNPEVLREIDRLKAQLNELVNTNGRSQEQLIRLQGERDEWKRERSKVET 1340
Cdd:COG3206    249 LGSGPDAL----------------PELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720364114 1341 KMVSKevvrhekdpvLEKEAERLRQEVREAVQRRRATEDAVYEL---QNKLLLLERR 1394
Cdd:COG3206    313 RILAS----------LEAELEALQAREASLQAQLAQLEARLAELpelEAELRRLERE 359
Filament pfam00038
Intermediate filament protein;
1433-1691 9.52e-03

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 40.29  E-value: 9.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1433 RQLELEVRQLGARVEEEEARLSFEEDRSKKLAaERELRQLTLKIQELEKRPPALQEKI--IMEEV----VKLEKDPDLER 1506
Cdd:pfam00038   21 RFLEQQNKLLETKISELRQKKGAEPSRLYSLY-EKEIEDLRRQLDTLTVERARLQLELdnLRLAAedfrQKYEDELNLRT 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1507 STEA----LRRELDQEKNRVTELHRECQGLQVQVDLLQKTKSQE-----KTIYKEVIRVEKDPVLEGERARvweILNRER 1577
Cdd:pfam00038  100 SAENdlvgLRKDLDEATLARVDLEAKIESLKEELAFLKKNHEEEvrelqAQVSDTQVNVEMDAARKLDLTS---ALAEIR 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1578 A-----ARKGREEDVRSLQERIdraEALRRSWSREEAELQRARDQASQDCGRLQRQLRELEQQKQQKArqlqeegRLLSQ 1652
Cdd:pfam00038  177 AqyeeiAAKNREEAEEWYQSKL---EELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLKKQKA-------SLERQ 246

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1720364114 1653 KTESERQKAAQRSQA---VTQLEAAILQEKDkiyEKERTLRD 1691
Cdd:pfam00038  247 LAETEERYELQLADYqelISELEAELQETRQ---EMARQLRE 285
PRK15483 PRK15483
type III restriction-modification system endonuclease;
1413-1575 9.67e-03

type III restriction-modification system endonuclease;


Pssm-ID: 237972 [Multi-domain]  Cd Length: 986  Bit Score: 41.17  E-value: 9.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1413 KLREEHSRLSRSldEEVGRrrQLELEVRQLGARVEEEEARLSFEEDRSKKLAAERELRQLTLKiQELEKRPPALQEKIIM 1492
Cdd:PRK15483   525 KLRSSGSETSKL--QEVGR--GLRLPVDENGHRVSQEEFRLNYLIDYDEKDFASKLVGEINSD-SKVQLNEEKLTEEMIQ 599

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114 1493 EEVVKLEK-DPDLerSTEALRRELDQEK-------------NRVTELHRECQGLQVQVDLLQKTKSQEKTIYKevIRVEK 1558
Cdd:PRK15483   600 KIVTEKQKvDPDF--TELRLLEDLDDKKiidrsnnfkedgfDWLLEAYPELFQTGLRKGKVRDNKPASKLTVK--LRKEN 675

                          170
                   ....*....|....*..
gi 1720364114 1559 DPVLEGerarVWEILNR 1575
Cdd:PRK15483   676 YEELKS----LWEQINR 688
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
820-1024 9.84e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 9.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  820 KRLIQEILGREQDQATVSRLTRDLQEALQDYELQADTYRcslepALAVSAPKRLRVISLQESIQAQEknlakaytevaaa 899
Cdd:COG4913    613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQ-----RLAEYSWDEIDVASAEREIAELE------------- 674

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364114  900 eqQQLRQLEFAKKMLRkkELDEDIQAIHSARQGsgspAHARTAESEVLKTQLEEERKRVAEVQRDLEEQRQRLLQLRTQQ 979
Cdd:COG4913    675 --AELERLDASSDDLA--ALEEQLEELEAELEE----LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLE 746

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1720364114  980 PVARLEEKevVEFYRDPQLESNLSQA-ASRVEEEGKRRARLQAELE 1024
Cdd:COG4913    747 LRALLEER--FAAALGDAVERELRENlEERIDALRARLNRAEEELE 790
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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