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Conserved domains on  [gi|1039766407|ref|XP_017175412|]
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adenylate kinase 4, mitochondrial isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
adk super family cl36879
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 7-171 1.62e-70

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


The actual alignment was detected with superfamily member TIGR01351:

Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 212.48  E-value: 1.62e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------------- 48
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTplgkkakeymekgelvpdeivnqlvkerltqnddneng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ----GFPRTLVQAEALDGICD--VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDD 122
Cdd:TIGR01351  81 fildGFPRTLSQAEALDALLEepIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1039766407 123 KPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGT-ETNRIWPYVYTLFS 171
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
 
Name Accession Description Interval E-value
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 7-171 1.62e-70

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 212.48  E-value: 1.62e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------------- 48
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTplgkkakeymekgelvpdeivnqlvkerltqnddneng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ----GFPRTLVQAEALDGICD--VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDD 122
Cdd:TIGR01351  81 fildGFPRTLSQAEALDALLEepIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1039766407 123 KPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGT-ETNRIWPYVYTLFS 171
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
ADK pfam00406
Adenylate kinase;
10-148 6.45e-69

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 207.55  E-value: 6.45e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  10 ILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT----------------------------------------- 48
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTelgkeakeymdkgelvpdevvvglvkerleqndckngflld 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 GFPRTLVQAEALD----GICDVDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDDKP 124
Cdd:pfam00406  81 GFPRTVPQAEALEelleRGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 1039766407 125 EAVAARLRRYKDAAKPVIELYKSR 148
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 7-157 2.43e-63

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 194.19  E-value: 2.43e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------------- 48
Cdd:COG0563     2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTelgkkakeymdagelvpdeiviglvkerlaqpdcangf 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ---GFPRTLVQAEALDGICD-----VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQE 120
Cdd:COG0563    82 ildGFPRTVAQAEALDELLAelgikLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1039766407 121 DDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGT 157
Cdd:COG0563   162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
adk PRK00279
adenylate kinase; Reviewed
 6-157 1.13e-59

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 184.97  E-value: 1.13e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT------------------------------------- 48
Cdd:PRK00279    1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTelgkeaksymdagelvpdeiviglvkerlaqpdckng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ----GFPRTLVQAEALDGIC-----DVDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQ 119
Cdd:PRK00279   81 flldGFPRTIPQAEALDEMLkelgiKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1039766407 120 EDDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGT 157
Cdd:PRK00279  161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGT 198
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 7-159 2.92e-57

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 178.20  E-value: 2.92e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------------- 48
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTelgkkakeyidsgklvpdeivikllkerlkkpdckkgf 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ---GFPRTLVQAEALDGICD----VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLdfnppqvqGIDDITGEPLVQQED 121
Cdd:cd01428    81 ildGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1039766407 122 DKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGTET 159
Cdd:cd01428   153 DNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
 
Name Accession Description Interval E-value
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 7-171 1.62e-70

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 212.48  E-value: 1.62e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------------- 48
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTplgkkakeymekgelvpdeivnqlvkerltqnddneng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ----GFPRTLVQAEALDGICD--VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDD 122
Cdd:TIGR01351  81 fildGFPRTLSQAEALDALLEepIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1039766407 123 KPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGT-ETNRIWPYVYTLFS 171
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
ADK pfam00406
Adenylate kinase;
10-148 6.45e-69

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 207.55  E-value: 6.45e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  10 ILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT----------------------------------------- 48
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTelgkeakeymdkgelvpdevvvglvkerleqndckngflld 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 GFPRTLVQAEALD----GICDVDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDDKP 124
Cdd:pfam00406  81 GFPRTVPQAEALEelleRGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 1039766407 125 EAVAARLRRYKDAAKPVIELYKSR 148
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 7-157 2.43e-63

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 194.19  E-value: 2.43e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------------- 48
Cdd:COG0563     2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTelgkkakeymdagelvpdeiviglvkerlaqpdcangf 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ---GFPRTLVQAEALDGICD-----VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQE 120
Cdd:COG0563    82 ildGFPRTVAQAEALDELLAelgikLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1039766407 121 DDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGT 157
Cdd:COG0563   162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
adk PRK00279
adenylate kinase; Reviewed
 6-157 1.13e-59

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 184.97  E-value: 1.13e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT------------------------------------- 48
Cdd:PRK00279    1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTelgkeaksymdagelvpdeiviglvkerlaqpdckng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ----GFPRTLVQAEALDGIC-----DVDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQ 119
Cdd:PRK00279   81 flldGFPRTIPQAEALDEMLkelgiKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1039766407 120 EDDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGT 157
Cdd:PRK00279  161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGT 198
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 7-159 2.92e-57

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 178.20  E-value: 2.92e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------------- 48
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTelgkkakeyidsgklvpdeivikllkerlkkpdckkgf 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ---GFPRTLVQAEALDGICD----VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLdfnppqvqGIDDITGEPLVQQED 121
Cdd:cd01428    81 ildGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1039766407 122 DKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGTET 159
Cdd:cd01428   153 DNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
PLN02674 PLN02674
adenylate kinase
 7-153 8.98e-41

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 137.71  E-value: 8.98e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------------- 48
Cdd:PLN02674   33 RLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTplgikakeamdkgelvsddlvvgiideamkkpscqkgf 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ---GFPRTLVQAEALDGICD-----VDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQE 120
Cdd:PLN02674  113 ildGFPRTVVQAQKLDEMLAkqgakIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQRK 192

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1039766407 121 DDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQ 153
Cdd:PLN02674  193 DDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVAN 225
PRK14530 PRK14530
adenylate kinase; Provisional
 1-163 3.87e-38

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 130.29  E-value: 3.87e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   1 MASKllRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLREN---------LKTGT----------------------- 48
Cdd:PRK14530    1 MSQP--RILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRANkqmdisdmdTEYDTpgeymdagelvpdavvneiveea 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ----------GFPRTLVQAEALDGICDVDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQ 118
Cdd:PRK14530   79 lsdadgfvldGYPRNLEQAEYLESITDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGGELIQ 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1039766407 119 QEDDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGTET-NRIW 163
Cdd:PRK14530  159 RDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTpDEVW 204
PLN02459 PLN02459
probable adenylate kinase
 9-154 3.50e-26

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 100.31  E-value: 3.50e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   9 VILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT---------------------------------------- 48
Cdd:PLN02459   33 VFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGplgaqlkeivnqgklvpdeiifsllskrleageeegesgf 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ---GFPRTLVQAEALDGICDVDLVISLNIPFETLKDR-LSRRwIHPSSGRVYNL-DFNPPQVQGIDDITGEPL------- 116
Cdd:PLN02459  113 ildGFPRTVRQAEILEGVTDIDLVVNLKLREEVLVEKcLGRR-ICSECGKNFNVaDIDLKGEDGRPGIVMPPLlpppeca 191

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1039766407 117 ---VQQEDDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQF 154
Cdd:PLN02459  192 sklITRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEF 232
PRK14526 PRK14526
adenylate kinase; Provisional
 6-145 1.73e-24

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 94.92  E-value: 1.73e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT------------------------------------- 48
Cdd:PRK14526    1 MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTplgkeikqivengqlvpdsitikivedkintiknndn 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ----GFPRTLVQAEALDGICDVDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQEDDKP 124
Cdd:PRK14526   81 fildGFPRNINQAKALDKFLPNIKIINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQRKDDKE 160

                         170       180
                  ....*....|....*....|.
gi 1039766407 125 EAVAARLRRYKDAAKPVIELY 145
Cdd:PRK14526  161 ESLKTRLQEYKLQTKPLIEFY 181
PLN02842 PLN02842
nucleotide kinase
 9-147 6.59e-23

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 94.54  E-value: 6.59e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   9 VILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT---------------------------------------- 48
Cdd:PLN02842    1 MISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTdigkrakefmnsgrlvpdeiviamvtgrlsredakekgwl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 --GFPRTLVQAEALDGI-CDVDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQvqgiDDITGEPLVQQEDDKPE 125
Cdd:PLN02842   81 ldGYPRSFAQAQSLEKLkIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPE----SEEIKARLITRPDDTEE 156

                         170       180
                  ....*....|....*....|..
gi 1039766407 126 AVAARLRRYKDAAKPVIELYKS 147
Cdd:PLN02842  157 KVKARLQIYKKNAEAILSTYSD 178
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 10-153 1.42e-22

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 89.10  E-value: 1.42e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  10 ILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGTGFPRTLVQAEALDGICDVDLVISLnipfetLKDRLSRRwIH 89
Cdd:TIGR01360   8 IVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDL------LKDAMVAA-LG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  90 PSSGrvYNLDFNPPQV-QGID--------------DITGEPLVQQ----------EDDKPEAVAARLRRYKDAAKPVIEL 144
Cdd:TIGR01360  81 TSKG--FLIDGYPREVkQGEEferrigpptlvlyfDCSEDTMVKRllkraetsgrVDDNEKTIKKRLETYYKATEPVIAY 158


                  ....*....
gi 1039766407 145 YKSRGVLHQ 153
Cdd:TIGR01360 159 YETKGKLRK 167
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 10-171 1.90e-19

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 80.88  E-value: 1.90e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  10 ILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLK-----TGT------------------------------------ 48
Cdd:TIGR01359   4 VLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKregseNGSliesyikegkivpsevtvellkkaiqedgsskkfli 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 -GFPRTLVQAEA----LDGICDVDLVISLNIPFETLKDRLSRRwiHPSSGRVynldfnppqvqgidditgeplvqqeDDK 123
Cdd:TIGR01359  84 dGFPRNEENLEAweklMDNKVNFKFVLFFDCPEETMIKRLLKR--GQTSGRV-------------------------DDN 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1039766407 124 PEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGTET-NRIWPYVYTLFS 171
Cdd:TIGR01359 137 IETLKKRFRTYNEETLPIIEHFENKGKVKEINAEGSvEEVFEDVEKIFA 185
PRK14527 PRK14527
adenylate kinase; Provisional
 7-159 7.89e-18

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 76.75  E-value: 7.89e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVI-LGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT------------------------------------- 48
Cdd:PRK14527    7 KVVIfLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTelgqrakpimeagdlvpdelilalirdelagmepvrv 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ---GFPRTLVQAEALDGICD-----VDLVISLNIPFETLKDRLSRRwihpssGRvynldfnppqvqgidditgepLVQQE 120
Cdd:PRK14527   87 ifdGFPRTLAQAEALDRLLEelgarLLAVVLLEVPDEELIRRIVER------AR---------------------QEGRS 139

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1039766407 121 DDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGTET 159
Cdd:PRK14527  140 DDNEETVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGT 178
PRK13808 PRK13808
adenylate kinase; Provisional
 6-148 1.98e-17

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 78.01  E-value: 1.98e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT------------------------------------- 48
Cdd:PRK13808    1 MRLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTpvglkakdimasgglvpdevvvgiisdrieqpdaang 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ----GFPRTLVQAEALDGIC-----DVDLVISLNIPFETLKDRLSRRwIHPSSGRvynldfnppqvqgidditGEPLvqQ 119
Cdd:PRK13808   81 fildGFPRTVPQAEALDALLkdkqlKLDAVVELRVNEGALLARVETR-VAEMRAR------------------GEEV--R 139

                         170       180
                  ....*....|....*....|....*....
gi 1039766407 120 EDDKPEAVAARLRRYKDAAKPVIELYKSR 148
Cdd:PRK13808  140 ADDTPEVLAKRLASYRAQTEPLVHYYSEK 168
PRK14531 PRK14531
adenylate kinase; Provisional
 1-151 4.04e-17

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 74.85  E-value: 4.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   1 MASKLLravILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------- 48
Cdd:PRK14531    1 MKQRLL---FLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSalgqeaeavmnrgelvsdalvlaivesqlkal 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 --------GFPRTLVQAEALDgicdvDLVISLNIPFETlkdrlsrrwihpssgrVYNLDFNppqvqgiDDITGEPLVQ-- 118
Cdd:PRK14531   78 nsggwlldGFPRTVAQAEALE-----PLLEELKQPIEA----------------VVLLELD-------DAVLIERLLArg 129

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1039766407 119 QEDDKPEAVAARLRRYKDAAKPVIELYKSRGVL 151
Cdd:PRK14531  130 RADDNEAVIRNRLEVYREKTAPLIDHYRQRGLL 162
PRK14532 PRK14532
adenylate kinase; Provisional
 9-156 2.47e-16

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 72.93  E-value: 2.47e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   9 VILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT---------------------------------------- 48
Cdd:PRK14532    4 ILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSelgqrvkgimdrgelvsdeivialieerlpeaeaaggaif 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 -GFPRTLVQAEALDGICD-----VDLVISLNIPFETLKDRLSRRWihPSSGRvynldfnppqvqgidditgeplvqqEDD 122
Cdd:PRK14532   84 dGFPRTVAQAEALDKMLAsrgqkIDVVIRLKVDDEALIERIVKRF--EEQGR-------------------------PDD 136

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1039766407 123 KPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSG 156
Cdd:PRK14532  137 NPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDG 170
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 6-150 4.61e-16

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 72.91  E-value: 4.61e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT------------------------------------- 48
Cdd:PTZ00088    7 LKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTtigkeiqkvvtsgnlvpdnlviaivkdeiakvtddcf 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ------GFPRTLVQAEALDGICDVDLVISLNIPFETLKDRLSRRWIHPSSGRVYNL------DFNPPQV---QGIDDITG 113
Cdd:PTZ00088   87 kgfildGFPRNLKQCKELGKITNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIahirsdPYDMPPIlppADCEGCKG 166

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1039766407 114 EP-LVQQEDDKPEAVAARLRRYKDAAKPVIELYKSRGV 150
Cdd:PTZ00088  167 NPkLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNENC 204
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 86-121 1.43e-15

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 66.72  E-value: 1.43e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1039766407  86 RWIHPSSGRVYNLDFNPPQVQGIDDITGEPLVQQED 121
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
PRK14528 PRK14528
adenylate kinase; Provisional
 7-159 1.73e-15

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 70.81  E-value: 1.73e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------------- 48
Cdd:PRK14528    3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTamgieakrymdagdlvpdsvvigiikdrireadckngf 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ---GFPRTLVQAEALDGIC-----DVDLVISLNIPFETLKDRLSRRWIhpSSGRvynldfnppqvqgidditgeplvqqE 120
Cdd:PRK14528   83 lldGFPRTVEQADALDALLknegkSIDKAINLEVPDGELLKRLLGRAE--IEGR-------------------------A 135

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1039766407 121 DDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGTET 159
Cdd:PRK14528  136 DDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGS 174
AAA_17 pfam13207
AAA domain;
11-96 2.74e-15

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 68.81  E-value: 2.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  11 LGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT---------------------------------------GFP 51
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERGlvedrdemrklplepqkelqklaaeriaeeageggvivdGHP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1039766407  52 RTLVQAEALDGI-------CDVDLVISLNIPFETLKDRLSRRwihPSSGRVY 96
Cdd:pfam13207  81 RIKTPAGYLPGLpvevlreLKPDAIILLEADPEEILERRLKD---RTRGRDD 129
adk PRK02496
adenylate kinase; Provisional
 7-159 9.63e-15

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 68.62  E-value: 9.63e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT-------------------------------------- 48
Cdd:PRK02496    3 RLIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTplgikaqgymdkgelvpdqlvldlvqerlqqpdaangw 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  49 ---GFPRTLVQAEALDGICD-----VDLVISLNIPFETLKDRLSRRwihpssGRvynldfnppqvqgidditgeplvqqE 120
Cdd:PRK02496   83 ildGFPRKVTQAAFLDELLQeigqsGERVVNLDVPDDVVVERLLAR------GR-------------------------K 131

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1039766407 121 DDKPEAVAARLRRYKDAAKPVIELYKSRGVLHQFSGTET 159
Cdd:PRK02496  132 DDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQS 170
PLN02200 PLN02200
adenylate kinase family protein
 10-171 2.08e-12

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 62.99  E-value: 2.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  10 ILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT----------------------------------------G 49
Cdd:PLN02200   48 VLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSehgamilntikegkivpsevtvkliqkemessdnnkflidG 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  50 FPRTLVQAEALDGI--CDVDLVISLNIPFETLKDRLSRRwihpSSGRVynldfnppqvqgidditgeplvqqeDDKPEAV 127
Cdd:PLN02200  128 FPRTEENRIAFERIigAEPNVVLFFDCPEEEMVKRVLNR----NQGRV-------------------------DDNIDTI 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1039766407 128 AARLRRYKDAAKPVIELYKSRGVLHQFSGTET-NRIWPYVYTLFS 171
Cdd:PLN02200  179 KKRLKVFNALNLPVIDYYSKKGKLYTINAVGTvDEIFEQVRPIFA 223
PRK14529 PRK14529
adenylate kinase; Provisional
 9-111 1.76e-09

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 54.73  E-value: 1.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   9 VILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTGT---------------------------------------- 48
Cdd:PRK14529    4 LIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTelgkkakeyidrgdlvpdditipmiletlkqdgkngwlld 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039766407  49 GFPRTLVQAEALD------GIcDVDLVISLNIPFETLKDRLSRRwihpssgRVYNLDFNPPQVQGIDDI 111
Cdd:PRK14529   84 GFPRNKVQAEKLWealqkeGM-KLDYVIEILLPREVAKNRIMGR-------RLCKNDNNHPNNIFIDAI 144
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 9-42 5.97e-08

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 50.11  E-value: 5.97e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1039766407   9 VILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRE 42
Cdd:TIGR02173   4 TISGPPGSGKTTVAKILAEKLSLKLISAGDIFRE 37
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 10-37 2.96e-07

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 47.48  E-value: 2.96e-07
                          10        20
                  ....*....|....*....|....*...
gi 1039766407  10 ILGPPGSGKGTVCERIAQNFGLQHLSSG 37
Cdd:cd02020     4 IDGPAGSGKSTVAKLLAKKLGLPYLDTG 31
PRK04182 PRK04182
cytidylate kinase; Provisional
 6-42 6.65e-07

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 47.11  E-value: 6.65e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1039766407   6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRE 42
Cdd:PRK04182    1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRE 37
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 10-41 6.48e-06

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 44.60  E-value: 6.48e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1039766407  10 ILGPPGSGKGTVCERIAQNFGLQHLSSGHLLR 41
Cdd:pfam02224   3 IDGPSGSGKSTVARILARKLGYKYLDTGAMYR 34
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 9-89 2.91e-05

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 42.24  E-value: 2.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   9 VILGPPGSGKGTVCERIAQNFGLQHL--------------SSGHLLREN--------------LKTGTGFPRTLVQAEAL 60
Cdd:cd02021     3 VVMGVSGSGKSTVGKALAERLGAPFIdgddlhppaniakmAAGIPLNDEdrwpwlqaltdallAKLASAGEGVVVACSAL 82

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1039766407  61 ---------DGICDVDLVIS-LNIPFETLKDRLSRRWIH 89
Cdd:cd02021    83 kriyrdilrGGAANPRVRFVhLDGPREVLAERLAARKGH 121
cmk TIGR00017
cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the ...
 10-41 1.04e-04

cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the phosphorylation of cytidine 5-monophosphate (dCMP) to cytidine 5 -diphosphate (dCDP) in the presence of ATP or GTP. UMP and dCMP can also act as acceptors. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 129128 [Multi-domain]  Cd Length: 217  Bit Score: 41.26  E-value: 1.04e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1039766407  10 ILGPPGSGKGTVCERIAQNFGLQHLSSGHLLR 41
Cdd:TIGR00017   7 IDGPSGAGKSTVAKAVAEKLGYAYLDSGAMYR 38
PRK11860 PRK11860
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
10-41 1.78e-04

bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;


Pssm-ID: 237003 [Multi-domain]  Cd Length: 661  Bit Score: 41.19  E-value: 1.78e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1039766407  10 ILGPPGSGKGTVCERIAQNFGLQHLSSGHLLR 41
Cdd:PRK11860  447 IDGPTASGKGTVAARVAEALGYHYLDSGALYR 478
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
12-37 2.19e-04

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 40.39  E-value: 2.19e-04
                          10        20
                  ....*....|....*....|....*.
gi 1039766407  12 GPPGSGKGTVCERIAQNFGLQHLSSG 37
Cdd:COG0283     7 GPAGSGKSTVAKALAKRLGYHYLDTG 32
AAA_18 pfam13238
AAA domain;
9-86 6.12e-04

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 38.18  E-value: 6.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   9 VILGPPGSGKGTVCERIAQNFGLqHLSSGHLLRENLKTGTGFP----------------RTLVQAEALDGICDVDLV--- 69
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGF-GDNVRDLALENGLVLGDDPetreskrldedkldrlLDLLEENAALEEGGNLIIdgh 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1039766407  70 --------------ISLNIPFETLKDRLSRR 86
Cdd:pfam13238  81 laeleperakdlvgIVLRASPEELLERLEKR 111
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
12-86 9.37e-04

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 37.97  E-value: 9.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407  12 GPPGSGKGTVCERIAQNFGLQHLSS--------GHLL---------------------RENLKTGT------GFP----R 52
Cdd:COG0645     6 GLPGSGKSTLARALAERLGAVRLRSdvvrkrlfGAGLaplerspeatartyarllalaRELLAAGRsvildaTFLrraqR 85

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1039766407  53 TLVQAEALDgiCDVDLV-ISLNIPFETLKDRLSRR 86
Cdd:COG0645    86 EAFRALAEE--AGAPFVlIWLDAPEEVLRERLEAR 118
PRK09518 PRK09518
bifunctional cytidylate kinase/GTPase Der; Reviewed
 6-41 2.20e-03

bifunctional cytidylate kinase/GTPase Der; Reviewed


Pssm-ID: 236546 [Multi-domain]  Cd Length: 712  Bit Score: 37.85  E-value: 2.20e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1039766407   6 LRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLR 41
Cdd:PRK09518    2 IIVAIDGPAGVGKSSVSRALAQYLGYAYLDTGAMYR 37
aroK PRK00131
shikimate kinase; Reviewed
 7-85 2.34e-03

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 37.09  E-value: 2.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039766407   7 RAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLREnlKTGT------------GFpRTLvQAEALDGICDV-DLVIS-- 71
Cdd:PRK00131    6 NIVLIGFMGAGKSTIGRLLAKRLGYDFIDTDHLIEA--RAGKsipeifeeegeaAF-REL-EEEVLAELLARhNLVIStg 81

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1039766407  72 ---------------------LNIPFETLKDRLSR 85
Cdd:PRK00131   82 ggavlreenrallrergtvvyLDASFEELLRRLRR 116
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
12-42 4.76e-03

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 36.34  E-value: 4.76e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1039766407  12 GPPGSGKGTVCERIAQNFGLQHLsSGHLLRE 42
Cdd:COG1102     7 REPGSGGTTIAKRLAEKLGLPLY-DGEILRE 36
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
9-39 7.29e-03

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 36.22  E-value: 7.29e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1039766407   9 VILGPPGSGKGTVCERIAqnfGLQHLSSGHL 39
Cdd:PRK10851   32 ALLGPSGSGKTTLLRIIA---GLEHQTSGHI 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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