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Conserved domains on  [gi|1039743027|ref|XP_017170847|]
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zinc finger protein 40 isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 2298-2691 2.89e-10

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.50  E-value: 2.89e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2298 PPADTPRSPGHQLSVHSSESDVLRSPAAGNPAAGSPGA-AVQDSSVGLPPAVAQLNPQPAARisssvSPHPDSQDQKQQI 2376
Cdd:PHA03247  2570 PPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDpRGPAPPSPLPPDTHAPDPPPPSP-----SPAANEPDPHPPP 2644

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2377 ILQPPPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVTAGLTYSTFVPIQAGPMQLTIPAVSVIHRTVGTSGDTI 2456
Cdd:PHA03247  2645 TVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2457 TEASGAPNRPTGVAELSSVVPCIPIgqihVPGLQNlsPPALQSLTSLGMETvnlvglANATVGPQGHPPGLALNAVGLQV 2536
Cdd:PHA03247  2725 PAAARQASPALPAAPAPPAVPAGPA----TPGGPA--RPARPPTTAGPPAP------APPAAPAAGPPRRLTRPAVASLS 2792

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2537 LANAPAQSSPAPPAHIQGLQILNIALPTLIPSVGPVAVGTTGTPETTAPNSKAMELQMPAGQGHSAEPP---QGSPEGPQ 2613
Cdd:PHA03247  2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrrRPPSRSPA 2872

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039743027 2614 ETPQTVSGPSADH-ARPEDSTKMDTKKGPSAGHVLPGRSPAQAQPAPTPEALQKVATSAPPSLPTDRAAPRPPVPHRQP 2691
Cdd:PHA03247  2873 AKPAAPARPPVRRlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAG 2951
zf-H2C2_2 pfam13465
Zinc-finger double domain;
2088-2113 1.19e-05

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 1.19e-05
                           10        20
                   ....*....|....*....|....*.
gi 1039743027 2088 MLKKHIRTHTDVRPYHCSYCNFSFKT 2113
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
422-446 9.96e-05

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.20  E-value: 9.96e-05
                           10        20
                   ....*....|....*....|....*
gi 1039743027  422 LLKHIRSHTGERPYPCVTCGFSFKT 446
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 2074-2096 2.54e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


:

Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 40.36  E-value: 2.54e-04
                           10        20
                   ....*....|....*....|...
gi 1039743027 2074 YICEECGIRCKKPSMLKKHIRTH 2096
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 2099-2130 1.25e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 38.39  E-value: 1.25e-03
                            10        20        30
                    ....*....|....*....|....*....|..
gi 1039743027  2099 VRPYHCSYCNFSFKTKGNLTKHMKSKAHSKKC 2130
Cdd:smart00451    1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNV 32
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2298-2691 2.89e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.50  E-value: 2.89e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2298 PPADTPRSPGHQLSVHSSESDVLRSPAAGNPAAGSPGA-AVQDSSVGLPPAVAQLNPQPAARisssvSPHPDSQDQKQQI 2376
Cdd:PHA03247  2570 PPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDpRGPAPPSPLPPDTHAPDPPPPSP-----SPAANEPDPHPPP 2644

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2377 ILQPPPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVTAGLTYSTFVPIQAGPMQLTIPAVSVIHRTVGTSGDTI 2456
Cdd:PHA03247  2645 TVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2457 TEASGAPNRPTGVAELSSVVPCIPIgqihVPGLQNlsPPALQSLTSLGMETvnlvglANATVGPQGHPPGLALNAVGLQV 2536
Cdd:PHA03247  2725 PAAARQASPALPAAPAPPAVPAGPA----TPGGPA--RPARPPTTAGPPAP------APPAAPAAGPPRRLTRPAVASLS 2792

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2537 LANAPAQSSPAPPAHIQGLQILNIALPTLIPSVGPVAVGTTGTPETTAPNSKAMELQMPAGQGHSAEPP---QGSPEGPQ 2613
Cdd:PHA03247  2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrrRPPSRSPA 2872

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039743027 2614 ETPQTVSGPSADH-ARPEDSTKMDTKKGPSAGHVLPGRSPAQAQPAPTPEALQKVATSAPPSLPTDRAAPRPPVPHRQP 2691
Cdd:PHA03247  2873 AKPAAPARPPVRRlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAG 2951
zf-H2C2_2 pfam13465
Zinc-finger double domain;
2088-2113 1.19e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 1.19e-05
                           10        20
                   ....*....|....*....|....*.
gi 1039743027 2088 MLKKHIRTHTDVRPYHCSYCNFSFKT 2113
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
422-446 9.96e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.20  E-value: 9.96e-05
                           10        20
                   ....*....|....*....|....*
gi 1039743027  422 LLKHIRSHTGERPYPCVTCGFSFKT 446
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 2074-2096 2.54e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 40.36  E-value: 2.54e-04
                           10        20
                   ....*....|....*....|...
gi 1039743027 2074 YICEECGIRCKKPSMLKKHIRTH 2096
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 2283-2687 3.16e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 46.30  E-value: 3.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2283 AKARQSTEKDEHEQAPPADTPRSPGHQLSVHSSESDvlrspaagNPAAGSPGAAVQDSSVGLPPAVAQLNPQPAARISSS 2362
Cdd:pfam03154   80 AKRQREKGASDTEEPERATAKKSKTQEISRPNSPSE--------GEGESSDGRSVNDEGSSDPKDIDQDNRSTSPSIPSP 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2363 VSPHPDSQDQKQQIILQPPPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVTAGLTYSTFVPIQAgpmQLTIPAV 2442
Cdd:pfam03154  152 QDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQT---QSTAAPH 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2443 SVIHRTVGTSGDTITeASGAPNRPTGVAELSSVVPCIPIGQIHVPGLQNLSPPALQSLTSLGMETVNLVGLANATVGPQG 2522
Cdd:pfam03154  229 TLIQQTPTLHPQRLP-SPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQS 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2523 H---PPGLALNAVGLQVLANAPAQSSPAP--PAHIQGLQILNIALPTLIPSvgpvavgttgtPETTAPnskamelQMPAG 2597
Cdd:pfam03154  308 QvppGPSPAAPGQSQQRIHTPPSQSQLQSqqPPREQPLPPAPLSMPHIKPP-----------PTTPIP-------QLPNP 369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2598 QGHSaEPPQGSPEGPQETPQTVSGPSADHARPEDSTKMDTKKGPSAGHVLPGRSPAQAQPAPTP-----EALQKVATSAP 2672
Cdd:pfam03154  370 QSHK-HPPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPvltqsQSLPPPAASHP 448

                          410
                   ....*....|....*
gi 1039743027 2673 PSLPTDRAAPRPPVP 2687
Cdd:pfam03154  449 PTSGLHQVPSQSPFP 463
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 2099-2130 1.25e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 38.39  E-value: 1.25e-03
                            10        20        30
                    ....*....|....*....|....*....|..
gi 1039743027  2099 VRPYHCSYCNFSFKTKGNLTKHMKSKAHSKKC 2130
Cdd:smart00451    1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNV 32
ZnF_C2H2 smart00355
zinc finger;
2102-2123 2.99e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 37.06  E-value: 2.99e-03
                            10        20
                    ....*....|....*....|..
gi 1039743027  2102 YHCSYCNFSFKTKGNLTKHMKS 2123
Cdd:smart00355    1 YRCPECGKVFKSKSALREHMRT 22
ZnF_C2H2 smart00355
zinc finger;
435-457 8.54e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 35.90  E-value: 8.54e-03
                            10        20
                    ....*....|....*....|...
gi 1039743027   435 YPCVTCGFSFKTKSNLYKHKKSH 457
Cdd:smart00355    1 YRCPECGKVFKSKSALREHMRTH 23
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2298-2691 2.89e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.50  E-value: 2.89e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2298 PPADTPRSPGHQLSVHSSESDVLRSPAAGNPAAGSPGA-AVQDSSVGLPPAVAQLNPQPAARisssvSPHPDSQDQKQQI 2376
Cdd:PHA03247  2570 PPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDpRGPAPPSPLPPDTHAPDPPPPSP-----SPAANEPDPHPPP 2644

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2377 ILQPPPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVTAGLTYSTFVPIQAGPMQLTIPAVSVIHRTVGTSGDTI 2456
Cdd:PHA03247  2645 TVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2457 TEASGAPNRPTGVAELSSVVPCIPIgqihVPGLQNlsPPALQSLTSLGMETvnlvglANATVGPQGHPPGLALNAVGLQV 2536
Cdd:PHA03247  2725 PAAARQASPALPAAPAPPAVPAGPA----TPGGPA--RPARPPTTAGPPAP------APPAAPAAGPPRRLTRPAVASLS 2792

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2537 LANAPAQSSPAPPAHIQGLQILNIALPTLIPSVGPVAVGTTGTPETTAPNSKAMELQMPAGQGHSAEPP---QGSPEGPQ 2613
Cdd:PHA03247  2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrrRPPSRSPA 2872

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039743027 2614 ETPQTVSGPSADH-ARPEDSTKMDTKKGPSAGHVLPGRSPAQAQPAPTPEALQKVATSAPPSLPTDRAAPRPPVPHRQP 2691
Cdd:PHA03247  2873 AKPAAPARPPVRRlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAG 2951
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2292-2683 1.93e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 60.34  E-value: 1.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2292 DEHEQAPPADTPRSPGHQLSVHSSESDVLRSPAAGNPAAG---------SPGAAVQDSSVGLPPAVAQLNPqPAARISSS 2362
Cdd:PHA03247  2620 DTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGrvsrprrarRLGRAAQASSPPQRPRRRAARP-TVGSLTSL 2698

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2363 VSPHPDSQDQkqqiilQPPPGLPSPQTHLFSHLPLHSQQQSRTPYNMVP--VGGIHVVTAGLTYSTFVPIQAGPMQLTIP 2440
Cdd:PHA03247  2699 ADPPPPPPTP------EPAPHALVSATPLPPGPAAARQASPALPAAPAPpaVPAGPATPGGPARPARPPTTAGPPAPAPP 2772

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2441 AVSVihrtvGTSGDTITEASGAPNRPTGVAELSSVVPCIPigQIHVPGLQNLSPPALQSLTSLGMETVNLVGLANATVGP 2520
Cdd:PHA03247  2773 AAPA-----AGPPRRLTRPAVASLSESRESLPSPWDPADP--PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGP 2845

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2521 QghPPGLALN---AVGLQVLANAPAQSSPAPPAHIQGLQILNIALPTLIPSVGPVAVGTTG-----TPETTAPNSKAMEL 2592
Cdd:PHA03247  2846 P--PPSLPLGgsvAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQperppQPQAPPPPQPQPQP 2923

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2593 QMPAgQGHSAEPPQGSPEGP-QETPQTVSGPSADHARPEdstkmdtkkgPSAGHVLPGRSPAQAQPAPTPEALQKVATSA 2671
Cdd:PHA03247  2924 PPPP-QPQPPPPPPPRPQPPlAPTTDPAGAGEPSGAVPQ----------PWLGALVPGRVAVPRFRVPQPAPSREAPASS 2992

                          410
                   ....*....|..
gi 1039743027 2672 PPSlPTDRAAPR 2683
Cdd:PHA03247  2993 TPP-LTGHSLSR 3003
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 2316-2691 1.62e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.84  E-value: 1.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2316 ESDVLRSPAAGNPAAGSPGAAVQDSSVGLPPAVAQLNPQPAARISSSVSPHPDSQDQkqqiilQPPPGLPSPQTHLFSHL 2395
Cdd:PRK07764   382 ERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPA------PAPPSPAGNAPAGGAPS 455

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2396 PLHSQQQSRTPynmvpvggihvvtagltystfVPIQAGPMQLTIPAvsvihrtvgtsgdtitEASGAPNRPTGVAELSSV 2475
Cdd:PRK07764   456 PPPAAAPSAQP---------------------APAPAAAPEPTAAP----------------APAPPAAPAPAAAPAAPA 498

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2476 VPCIPIGQIHVPGLQNLSPPALQSLTSLGMETVNLVgLANATVGPQ-------GHPPGLALNAVGLQ----VLANAPAQs 2544
Cdd:PRK07764   499 APAAPAGADDAATLRERWPEILAAVPKRSRKTWAIL-LPEATVLGVrgdtlvlGFSTGGLARRFASPgnaeVLVTALAE- 576

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2545 spappahiqglqILNIAL-PTLIPSVGPVAVGTTGTPETTAPNSKAMELQmPAGQGHSAEPPQGSPEGPQETPQTVSGPS 2623
Cdd:PRK07764   577 ------------ELGGDWqVEAVVGPAPGAAGGEGPPAPASSGPPEEAAR-PAAPAAPAAPAAPAPAGAAAAPAEASAAP 643

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039743027 2624 A-DHARPEDSTKMDTKKGPSAGHVLPGRSPAQAQPAPTPEALQKVATSAPPSLPTDRAAPRPPVPHRQP 2691
Cdd:PRK07764   644 ApGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAG 712
zf-H2C2_2 pfam13465
Zinc-finger double domain;
2088-2113 1.19e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 1.19e-05
                           10        20
                   ....*....|....*....|....*.
gi 1039743027 2088 MLKKHIRTHTDVRPYHCSYCNFSFKT 2113
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 2321-2691 2.05e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 50.37  E-value: 2.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2321 RSPAAGNPAAGSPGAAVQDSSVGLPPAVAQLNPQPAARISSSVSPHPDSQDQKQQ-IILQPPPGLPSPQTHLFSHLPLHS 2399
Cdd:PRK07764   380 RLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPApAPAPAPPSPAGNAPAGGAPSPPPA 459

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2400 QQQSRTPynmVPVGGIHVVTAGLTYSTFVPIQAG------PMQLTIPAVSVIHRTVGTSGDTITEASGAPNRPTGVAELS 2473
Cdd:PRK07764   460 AAPSAQP---APAPAAAPEPTAAPAPAPPAAPAPaaapaaPAAPAAPAGADDAATLRERWPEILAAVPKRSRKTWAILLP 536

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2474 SVVPCIPIGQI-----HVPGLQNL--SPPALQSLTSLGMETVNLVGLANATVGPQGHPPGLAlNAVGLQVLANAPAQSSP 2546
Cdd:PRK07764   537 EATVLGVRGDTlvlgfSTGGLARRfaSPGNAEVLVTALAEELGGDWQVEAVVGPAPGAAGGE-GPPAPASSGPPEEAARP 615

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2547 APPAHiqglqilnialPTliPSVGPVAVGTTGTPETTAPNSKAMELQMPAGQGHSAEPPQGSPEGPQETPQTVSGPSADH 2626
Cdd:PRK07764   616 AAPAA-----------PA--APAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPP 682

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039743027 2627 ARPED--STKMDTKKGPSAGHVLPGRSPAQAQPAPTPEALQKVATSAPPSLPTDRAAPRPPVPHRQP 2691
Cdd:PRK07764   683 PAPAPaaPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPP 749
zf-H2C2_2 pfam13465
Zinc-finger double domain;
422-446 9.96e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.20  E-value: 9.96e-05
                           10        20
                   ....*....|....*....|....*
gi 1039743027  422 LLKHIRSHTGERPYPCVTCGFSFKT 446
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2320-2687 1.23e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 1.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2320 LRSPAAGNPAAGSPGAA---VQDSSVGlPPAVAQLNPQPAARISS---SVSPHPDS----QDQKQQIILQPPPGLPSPQT 2389
Cdd:PHA03247  2543 LASDDAGDPPPPLPPAAppaAPDRSVP-PPRPAPRPSEPAVTSRArrpDAPPQSARprapVDDRGDPRGPAPPSPLPPDT 2621

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2390 HlfshlPLHSQQQSRTPYNMVPVGGIHVVTagltystfvPIQAGPMQLTIPAVSVIHRTVGTSGDTiTEASGAPNRPTGV 2469
Cdd:PHA03247  2622 H-----APDPPPPSPSPAANEPDPHPPPTV---------PPPERPRDDPAPGRVSRPRRARRLGRA-AQASSPPQRPRRR 2686

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2470 AelssvvpcipigqihvpglqnlSPPALQSLTSLgmetvnlvglanATVGPQGHPPGLA----LNAVGLQVLANAPAQSS 2545
Cdd:PHA03247  2687 A----------------------ARPTVGSLTSL------------ADPPPPPPTPEPAphalVSATPLPPGPAAARQAS 2732

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2546 PAPPAHiqglqilNIALPTLIPSVGPVAVGTTGTPETTAPnskamelqmPAgqghSAEPPQGSPEGPQETPQTVSGPSAD 2625
Cdd:PHA03247  2733 PALPAA-------PAPPAVPAGPATPGGPARPARPPTTAG---------PP----APAPPAAPAAGPPRRLTRPAVASLS 2792

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039743027 2626 HARPEDSTKMDTKKGPSAGHVLPGRSPAQAQPAPtpealqkvaTSAPPSLPTDRAAPRPPVP 2687
Cdd:PHA03247  2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAG---------PLPPPTSAQPTAPPPPPGP 2845
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 2074-2096 2.54e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 40.36  E-value: 2.54e-04
                           10        20
                   ....*....|....*....|...
gi 1039743027 2074 YICEECGIRCKKPSMLKKHIRTH 2096
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 2283-2687 3.16e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 46.30  E-value: 3.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2283 AKARQSTEKDEHEQAPPADTPRSPGHQLSVHSSESDvlrspaagNPAAGSPGAAVQDSSVGLPPAVAQLNPQPAARISSS 2362
Cdd:pfam03154   80 AKRQREKGASDTEEPERATAKKSKTQEISRPNSPSE--------GEGESSDGRSVNDEGSSDPKDIDQDNRSTSPSIPSP 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2363 VSPHPDSQDQKQQIILQPPPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVTAGLTYSTFVPIQAgpmQLTIPAV 2442
Cdd:pfam03154  152 QDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQT---QSTAAPH 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2443 SVIHRTVGTSGDTITeASGAPNRPTGVAELSSVVPCIPIGQIHVPGLQNLSPPALQSLTSLGMETVNLVGLANATVGPQG 2522
Cdd:pfam03154  229 TLIQQTPTLHPQRLP-SPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQS 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2523 H---PPGLALNAVGLQVLANAPAQSSPAP--PAHIQGLQILNIALPTLIPSvgpvavgttgtPETTAPnskamelQMPAG 2597
Cdd:pfam03154  308 QvppGPSPAAPGQSQQRIHTPPSQSQLQSqqPPREQPLPPAPLSMPHIKPP-----------PTTPIP-------QLPNP 369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2598 QGHSaEPPQGSPEGPQETPQTVSGPSADHARPEDSTKMDTKKGPSAGHVLPGRSPAQAQPAPTP-----EALQKVATSAP 2672
Cdd:pfam03154  370 QSHK-HPPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPvltqsQSLPPPAASHP 448

                          410
                   ....*....|....*
gi 1039743027 2673 PSLPTDRAAPRPPVP 2687
Cdd:pfam03154  449 PTSGLHQVPSQSPFP 463
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2520-2685 3.56e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.02  E-value: 3.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2520 PQGHPPGLALNAVGLQVLANAPAQSSPAP---PAHIQGLQILNIALPTLIPSVGPVAVGTTGTPETTAPNSKAMELQMPA 2596
Cdd:PRK12323   402 PPAAPAAAPAAAAAARAVAAAPARRSPAPealAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPA 481

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2597 GQGHSAEPPQGSPEGP--QETPQTVSGPSADharpedstkmDTKKGPSAGHVLPGRSPAQAQPAPTPEALQKVATSAP-- 2672
Cdd:PRK12323   482 RAAPAAAPAPADDDPPpwEELPPEFASPAPA----------QPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPap 551

                          170
                   ....*....|....*
gi 1039743027 2673 --PSLPTDRAAPRPP 2685
Cdd:PRK12323   552 raAAATEPVVAPRPP 566
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 2102-2123 8.58e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 38.82  E-value: 8.58e-04
                           10        20
                   ....*....|....*....|..
gi 1039743027 2102 YHCSYCNFSFKTKGNLTKHMKS 2123
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRT 22
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2514-2691 1.01e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.84  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2514 ANATVGPQGHPPGLALNAVGLQVLANAPAQSSPAPPAHIQglqilnialptlipsvgPVAVGTTGTPETTAPNSKAMELQ 2593
Cdd:PRK07003   392 GASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPA-----------------PPATADRGDDAADGDAPVPAKAN 454

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2594 MPAGqghSAEPPQGSPEGPQETPQTVSGPSADhaRPEDSTKMDTkkgPSAGHVLPGRSPAQAQPAPtPEALQKVATSAPP 2673
Cdd:PRK07003   455 ARAS---ADSRCDERDAQPPADSGSASAPASD--APPDAAFEPA---PRAAAPSAATPAAVPDARA-PAAASREDAPAAA 525

                          170
                   ....*....|....*...
gi 1039743027 2674 SLPTDRAAPRPPVPHRQP 2691
Cdd:PRK07003   526 APPAPEARPPTPAAAAPA 543
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 2099-2130 1.25e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 38.39  E-value: 1.25e-03
                            10        20        30
                    ....*....|....*....|....*....|..
gi 1039743027  2099 VRPYHCSYCNFSFKTKGNLTKHMKSKAHSKKC 2130
Cdd:smart00451    1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNV 32
ZnF_C2H2 smart00355
zinc finger;
2102-2123 2.99e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 37.06  E-value: 2.99e-03
                            10        20
                    ....*....|....*....|..
gi 1039743027  2102 YHCSYCNFSFKTKGNLTKHMKS 2123
Cdd:smart00355    1 YRCPECGKVFKSKSALREHMRT 22
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 2295-2413 3.08e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.78  E-value: 3.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2295 EQAPPADTPRSPGHQLSVhssesdVLRSPAAGNPAAGSPGAAVQDSSVGLPPAVAQLNPQPAARISSSVSPHPDSQDQKQ 2374
Cdd:PRK14951   385 EAAAPAAAPVAQAAAAPA------PAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPE 458

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1039743027 2375 QIIL----QPPPGLPSPQthlfshlPLHSQQQSRTPYNMVPVG 2413
Cdd:PRK14951   459 TVAIpvrvAPEPAVASAA-------PAPAAAPAAARLTPTEEG 494
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 2516-2687 4.56e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 4.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2516 ATVGPQGHPPGLALNAVGLQVLANAPAQSSPAPPAHIQGLQilniALPTLIPSVGPVAVGTTGTPETTAPNSKAmelqmP 2595
Cdd:PRK07764   627 PAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGD----GWPAKAGGAAPAAPPPAPAPAAPAAPAGA-----A 697

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2596 AGQGHSAEPPQGSPEGPQETPQTVSGPSADHARPEDSTKMDTKKgPSAGHVLPGRSPAQAQPAPTPEALQKVATSAPPSl 2675
Cdd:PRK07764   698 PAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPL-PPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPP- 775

                          170
                   ....*....|..
gi 1039743027 2676 PTDRAAPRPPVP 2687
Cdd:PRK07764   776 PSPPSEEEEMAE 787
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2534-2691 4.81e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 4.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2534 LQVLANAPAQS----SPAPPAHIqglqilnialptliPSVGPVAVGTTGTPETTAPNSKAMELQMPAGQGHSAEPPQGSP 2609
Cdd:PRK12323   358 LRMLAFRPGQSgggaGPATAAAA--------------PVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAP 423

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039743027 2610 EGPQETPQTVSGpsadhARPEDSTKMDTKKGPSAGhvlPGRSPAQAQPAPTPEALQKVATSAPPSLPTDRAAPRPPVPHR 2689
Cdd:PRK12323   424 ARRSPAPEALAA-----ARQASARGPGGAPAPAPA---PAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDD 495


                   ..
gi 1039743027 2690 QP 2691
Cdd:PRK12323   496 PP 497
ZnF_C2H2 smart00355
zinc finger;
435-457 8.54e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 35.90  E-value: 8.54e-03
                            10        20
                    ....*....|....*....|...
gi 1039743027   435 YPCVTCGFSFKTKSNLYKHKKSH 457
Cdd:smart00355    1 YRCPECGKVFKSKSALREHMRTH 23
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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