|
Name |
Accession |
Description |
Interval |
E-value |
| TLE_N |
pfam03920 |
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor ... |
17-132 |
2.96e-84 |
|
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor proteins are involved in oligomerization.
Pssm-ID: 461094 Cd Length: 117 Bit Score: 263.52 E-value: 2.96e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 17 FKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSAICAQMVPFLT 96
Cdd:pfam03920 1 FKFTVPETCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNAICAQVIPFLS 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 1039732848 97 QEHQQQVLQAVDRAKQVTVGELNSLLGQNQLQPLSH 132
Cdd:pfam03920 81 QEHQQQVAQAVERAKQVTMAELNAIIGQQQQLQAQH 116
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
436-688 |
4.13e-36 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 141.20 E-value: 4.13e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 436 RQLHTL-AHGEVVCAVTISSSTQHVYTGGK-GCVKVWDVGqpgSKTPVAQLDclNRDNYIRSCKLLPDGQSLIVGGEAST 513
Cdd:COG2319 153 KLLRTLtGHSGAVTSVAFSPDGKLLASGSDdGTVRLWDLA---TGKLLRTLT--GHTGAVRSVAFSPDGKLLASGSADGT 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 514 LSIWDLAapTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWT 593
Cdd:COG2319 228 VRLWDLA--TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLAS 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 594 GGLDNTVRCWDLREGRQLQQHD-FSSQIFSLGHCPNQDWLAVGMESSHVEVLHVR-KPEKYQLRLHESCVLSLKFASCGR 671
Cdd:COG2319 306 GSDDGTVRLWDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLAtGELLRTLTGHTGAVTSVAFSPDGR 385
|
250
....*....|....*..
gi 1039732848 672 WFVSTGKDNLLNAWRTP 688
Cdd:COG2319 386 TLASGSADGTVRLWDLA 402
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
429-686 |
2.39e-33 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 130.15 E-value: 2.39e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 429 TGIPRHARQLHTlahGEVVCAVTISSSTQhVYTGGK-GCVKVWDVGQPgsktpvaqlDCLNR----DNYIRSCKLLPDGQ 503
Cdd:cd00200 40 TGELLRTLKGHT---GPVRDVAASADGTY-LASGSSdKTIRLWDLETG---------ECVRTltghTSYVSSVAFSPDGR 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 504 SLIVGGEASTLSIWDLaaPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCID 583
Cdd:cd00200 107 ILSSSSRDKTIKVWDV--ETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 584 ISDYGTRLWTGGLDNTVRCWDLREGRQLQQHD-FSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPE-KYQLRLHESCV 661
Cdd:cd00200 185 FSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRgHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGEcVQTLSGHTNSV 264
|
250 260
....*....|....*....|....*
gi 1039732848 662 LSLKFASCGRWFVSTGKDNLLNAWR 686
Cdd:cd00200 265 TSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
245-422 |
1.60e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 55.33 E-value: 1.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 245 PSEPPSPVT--TPCGKAPLCIPARRDLTDSPASLASSLGSPLPRSKDIALNDLPTGTPASRSCGTSPPQDSSTPGPSSAS 322
Cdd:PHA03247 2739 PAPPAVPAGpaTPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL 2818
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 323 HLCQLAAQPAAPTDSIALRSPLTLSSPFTSSFSLGSHSTLNGDLSMPGSyvglHLSPQMAFESHPHLRGSSVSLPgiPVA 402
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPP----SRSPAAKPAAPARPPVRRLARP--AVS 2892
|
170 180
....*....|....*....|
gi 1039732848 403 KPAYSFHVSADGQmQPVPFP 422
Cdd:PHA03247 2893 RSTESFALPPDQP-ERPPQP 2911
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
569-604 |
9.47e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 45.77 E-value: 9.47e-07
10 20 30
....*....|....*....|....*....|....*.
gi 1039732848 569 VRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWD 604
Cdd:smart00320 5 LKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
569-604 |
1.24e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 42.72 E-value: 1.24e-05
10 20 30
....*....|....*....|....*....|....*.
gi 1039732848 569 VRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWD 604
Cdd:pfam00400 4 LKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| TLE_N |
pfam03920 |
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor ... |
17-132 |
2.96e-84 |
|
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor proteins are involved in oligomerization.
Pssm-ID: 461094 Cd Length: 117 Bit Score: 263.52 E-value: 2.96e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 17 FKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSAICAQMVPFLT 96
Cdd:pfam03920 1 FKFTVPETCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNAICAQVIPFLS 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 1039732848 97 QEHQQQVLQAVDRAKQVTVGELNSLLGQNQLQPLSH 132
Cdd:pfam03920 81 QEHQQQVAQAVERAKQVTMAELNAIIGQQQQLQAQH 116
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
436-688 |
4.13e-36 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 141.20 E-value: 4.13e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 436 RQLHTL-AHGEVVCAVTISSSTQHVYTGGK-GCVKVWDVGqpgSKTPVAQLDclNRDNYIRSCKLLPDGQSLIVGGEAST 513
Cdd:COG2319 153 KLLRTLtGHSGAVTSVAFSPDGKLLASGSDdGTVRLWDLA---TGKLLRTLT--GHTGAVRSVAFSPDGKLLASGSADGT 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 514 LSIWDLAapTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWT 593
Cdd:COG2319 228 VRLWDLA--TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLAS 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 594 GGLDNTVRCWDLREGRQLQQHD-FSSQIFSLGHCPNQDWLAVGMESSHVEVLHVR-KPEKYQLRLHESCVLSLKFASCGR 671
Cdd:COG2319 306 GSDDGTVRLWDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLAtGELLRTLTGHTGAVTSVAFSPDGR 385
|
250
....*....|....*..
gi 1039732848 672 WFVSTGKDNLLNAWRTP 688
Cdd:COG2319 386 TLASGSADGTVRLWDLA 402
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
326-690 |
1.36e-35 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 139.66 E-value: 1.36e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 326 QLAAQPAAPTDSIALRSPLTLSSPFTSSFSLGSHSTLNGDLSMPGSYVGLHLSPQMAFESHPHLRGSSVSLPGIPVAKPA 405
Cdd:COG2319 4 ADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 406 YSFhvSADGQMQPVPFPSDALVGTGIPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGK-GCVKVWDVGqpgSKTPVAQL 484
Cdd:COG2319 84 VAF--SPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSAdGTVRLWDLA---TGKLLRTL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 485 DclNRDNYIRSCKLLPDGQSLIVGGEASTLSIWDLAapTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQ 564
Cdd:COG2319 159 T--GHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLA--TGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 565 NQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQ-HDFSSQIFSLGHCPNQDWLAVGMESSHVEV 643
Cdd:COG2319 235 TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTlTGHSGGVNSVAFSPDGKLLASGSDDGTVRL 314
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1039732848 644 LHVRKPEK-YQLRLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYG 690
Cdd:COG2319 315 WDLATGKLlRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATG 362
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
429-686 |
2.39e-33 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 130.15 E-value: 2.39e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 429 TGIPRHARQLHTlahGEVVCAVTISSSTQhVYTGGK-GCVKVWDVGQPgsktpvaqlDCLNR----DNYIRSCKLLPDGQ 503
Cdd:cd00200 40 TGELLRTLKGHT---GPVRDVAASADGTY-LASGSSdKTIRLWDLETG---------ECVRTltghTSYVSSVAFSPDGR 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 504 SLIVGGEASTLSIWDLaaPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCID 583
Cdd:cd00200 107 ILSSSSRDKTIKVWDV--ETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 584 ISDYGTRLWTGGLDNTVRCWDLREGRQLQQHD-FSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPE-KYQLRLHESCV 661
Cdd:cd00200 185 FSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRgHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGEcVQTLSGHTNSV 264
|
250 260
....*....|....*....|....*
gi 1039732848 662 LSLKFASCGRWFVSTGKDNLLNAWR 686
Cdd:cd00200 265 TSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
389-697 |
2.71e-32 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 130.03 E-value: 2.71e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 389 LRGSSVSLPGIPVAKPAYSFHVSADGQMQPVPFPSDALVGTGIPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGK-GCV 467
Cdd:COG2319 23 AALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASAdGTV 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 468 KVWDVgqpgsKTPVAQLDCLNRDNYIRSCKLLPDGQSLIVGGEASTLSIWDLAapTPRIKAELTSSAPACYALAVSPDAK 547
Cdd:COG2319 103 RLWDL-----ATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLA--TGKLLRTLTGHSGAVTSVAFSPDGK 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 548 VCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQ-HDFSSQIFSLGHC 626
Cdd:COG2319 176 LLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTlTGHSGSVRSVAFS 255
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039732848 627 PNQDWLAVGMESSHVEVLHVR-KPEKYQLRLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQVT 697
Cdd:COG2319 256 PDGRLLASGSADGTVRLWDLAtGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT 327
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
443-687 |
3.38e-31 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 123.98 E-value: 3.38e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 443 HGEVVCAVTISSSTQHVYTGGK-GCVKVWDV-GQPGSKTPVAQLDClnrdnyIRSCKLLPDGQSLIVGGEASTLSIWDLa 520
Cdd:cd00200 8 HTGGVTCVAFSPDGKLLATGSGdGTIKVWDLeTGELLRTLKGHTGP------VRDVAASADGTYLASGSSDKTIRLWDL- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 521 aPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTV 600
Cdd:cd00200 81 -ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 601 RCWDLREGR---QLQQHDfsSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPE-KYQLRLHESCVLSLKFASCGRWFVST 676
Cdd:cd00200 160 KLWDLRTGKcvaTLTGHT--GEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKcLGTLRGHENGVNSVAFSPDGYLLASG 237
|
250
....*....|.
gi 1039732848 677 GKDNLLNAWRT 687
Cdd:cd00200 238 SEDGTIRVWDL 248
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
436-565 |
2.02e-12 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 69.94 E-value: 2.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 436 RQLHTLA-HGEVVCAVTISSSTQHVYTGGKGC-VKVWDVGqpgSKTPVAQLDclNRDNYIRSCKLLPDGQSLIVGGEAST 513
Cdd:COG2319 279 ELLRTLTgHSGGVNSVAFSPDGKLLASGSDDGtVRLWDLA---TGKLLRTLT--GHTGAVRSVAFSPDGKTLASGSDDGT 353
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1039732848 514 LSIWDLAapTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQN 565
Cdd:COG2319 354 VRLWDLA--TGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
568-690 |
5.30e-11 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 64.28 E-value: 5.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 568 MVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREG---RQLQQHdfSSQIFSLGHCPNQDWLAVGMESSHVEVL 644
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGellRTLKGH--TGPVRDVAASADGTYLASGSSDKTIRLW 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1039732848 645 HVRKPEK-YQLRLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYG 690
Cdd:cd00200 79 DLETGECvRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETG 125
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
498-697 |
5.64e-11 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 65.32 E-value: 5.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 498 LLPDGQSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPAcyALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTD 577
Cdd:COG2319 2 LSADGAALAAASADLALALLAAALGALLLLLLGLAAAVA--SLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 578 GASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQ-HDFSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPEK-YQLR 655
Cdd:COG2319 80 AVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTlTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLlRTLT 159
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1039732848 656 LHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQVT 697
Cdd:COG2319 160 GHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT 201
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
245-422 |
1.60e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 55.33 E-value: 1.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 245 PSEPPSPVT--TPCGKAPLCIPARRDLTDSPASLASSLGSPLPRSKDIALNDLPTGTPASRSCGTSPPQDSSTPGPSSAS 322
Cdd:PHA03247 2739 PAPPAVPAGpaTPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL 2818
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 323 HLCQLAAQPAAPTDSIALRSPLTLSSPFTSSFSLGSHSTLNGDLSMPGSyvglHLSPQMAFESHPHLRGSSVSLPgiPVA 402
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPP----SRSPAAKPAAPARPPVRRLARP--AVS 2892
|
170 180
....*....|....*....|
gi 1039732848 403 KPAYSFHVSADGQmQPVPFP 422
Cdd:PHA03247 2893 RSTESFALPPDQP-ERPPQP 2911
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
569-604 |
9.47e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 45.77 E-value: 9.47e-07
10 20 30
....*....|....*....|....*....|....*.
gi 1039732848 569 VRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWD 604
Cdd:smart00320 5 LKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
569-604 |
1.24e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 42.72 E-value: 1.24e-05
10 20 30
....*....|....*....|....*....|....*.
gi 1039732848 569 VRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWD 604
Cdd:pfam00400 4 LKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
198-405 |
8.69e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.24 E-value: 8.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 198 ESLVEEDHPSSRGGSGKQQRAEDkDLSGP----YDSEEDKSDyNLVVDEDQPSEPPSPVTTPCGKAPLCIPARRDLTDSP 273
Cdd:PHA03307 12 EAAAEGGEFFPRPPATPGDAADD-LLSGSqgqlVSDSAELAA-VTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 274 ASLAS-SLGSPLPRSKDIALNDLPTGTPASR----SCGTSPPQDSSTPGPSSASHLCQLAAQPAAPTDSIAlRSPLTLSS 348
Cdd:PHA03307 90 WSLSTlAPASPAREGSPTPPGPSSPDPPPPTpppaSPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPA-AVASDAAS 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1039732848 349 PFTSSFSLGSHSTLNGDLSMPGSYVGLhLSPQMAFESHPHLRGSSVSLP-GIPVAKPA 405
Cdd:PHA03307 169 SRQAALPLSSPEETARAPSSPPAEPPP-STPPAAASPRPPRRSSPISASaSSPAPAPG 225
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
498-605 |
1.35e-03 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 41.22 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732848 498 LLPDGQSLIVGGEAS-TLSIWDLAapTPRIKAEL-TSSAPacYALAVSPDAKVCFSCCSDGN-----IVVWDLQNQAMVR 570
Cdd:COG3391 117 VDPDGGRLYVADSGNgRVSVIDTA--TGKVVATIpVGAGP--HGIAVDPDGKRLYVANSGSNtvsviVSVIDTATGKVVA 192
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1039732848 571 QFQGHtDGASCIDISDYGTRLW--------TGGLDNTVRCWDL 605
Cdd:COG3391 193 TIPVG-GGPVGVAVSPDGRRLYvanrgsntSNGGSNTVSVIDL 234
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
523-562 |
2.12e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 36.52 E-value: 2.12e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1039732848 523 TPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWD 562
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
|