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Conserved domains on  [gi|767916541|ref|XP_011508860|]
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collagen alpha-4(IV) chain isoform X3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1430-1535 1.08e-53

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


:

Pssm-ID: 460201  Cd Length: 110  Bit Score: 183.18  E-value: 1.08e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  1430 FLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQrNDRSYWLAS 1509
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHTGNGEGHGQDLGSPGSCLERFRTMPFIECNGNGTCNYAS-NDYSYWLST 79

                           90       100       110
                   ....*....|....*....|....*....|.
gi 767916541  1510 AA-----PLPMMPLSEEAIRPYVSRCAVCEA 1535
Cdd:pfam01413   80 VEeqfrkPMSQTPKAGNELRSYISRCVVCEA 110
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1538-1650 9.47e-50

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


:

Pssm-ID: 460201  Cd Length: 110  Bit Score: 171.62  E-value: 9.47e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  1538 QAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTgAGDQGGGQALMSPGSCLEDFRAAPFLECQGRqGTCHFFANKYSFWLT 1617
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHT-GNGEGHGQDLGSPGSCLERFRTMPFIECNGN-GTCNYASNDYSYWLS 78

                           90       100       110
                   ....*....|....*....|....*....|...
gi 767916541  1618 TVkaDLQFSSaPAPDTLKESQAQRQKISRCQVC 1650
Cdd:pfam01413   79 TV--EEQFRK-PMSQTPKAGNELRSYISRCVVC 108
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 753-975 1.48e-18

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 90.35  E-value: 1.48e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  753 GCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGM 832
Cdd:NF038329  117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGP 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  833 KGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGfPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRG 912
Cdd:NF038329  197 RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGD-PGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767916541  913 LRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPG 975
Cdd:NF038329  276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 87-347 5.67e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 82.65  E-value: 5.67e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541   87 LSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGfpggrgalgpggplghp 166
Cdd:NF038329  115 GDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAG----------------- 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  167 gekgekgnsvfilgaVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPG 246
Cdd:NF038329  178 ---------------KDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPG 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  247 EVGQQGSPGPTLLveppdfclyKGEKGIKGIPGMVGLPGPPGRKGESGI----GAKGEKGIPGFPGPRGDPGSYGSPGFP 322
Cdd:NF038329  243 PTGEDGPQGPDGP---------AGKDGPRGDRGEAGPDGPDGKDGERGPvgpaGKDGQNGKDGLPGKDGKDGQNGKDGLP 313

                         250       260
                  ....*....|....*....|....*
gi 767916541  323 GLKGELGLVGDPGLFGLIGPKGDPG 347
Cdd:NF038329  314 GKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 640-843 2.05e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 74.56  E-value: 2.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  640 ERGHPGVPGHPGVRGPDGLKGQKGDT-ISCNVTYPGRHGPPGFDGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPgvNG 718
Cdd:NF038329  118 EKGEPGPAGPAGPAGEQGPRGDRGETgPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGP--QG 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  719 QKGIPG-DPAFGHLGPPGKRGLSGVPGIKGPRGDPGcPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGppghscERGAP 797
Cdd:NF038329  196 PRGETGpAGEQGPAGPAGPDGEAGPAGEDGPAGPAG-DGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRG------DRGEA 268

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 767916541  798 GIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPG 843
Cdd:NF038329  269 GPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPG 314
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 963-1183 1.58e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 55.68  E-value: 1.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  963 GRRGEPGRYGPPGfHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPa 1042
Cdd:NF038329  117 GEKGEPGPAGPAG-PAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQ- 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1043 shfgppgpkgepGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDhGMPGLRGQPGEMGDPGPRGLQGD 1122
Cdd:NF038329  195 ------------GPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPD-GDPGPTGEDGPQGPDGPAGKDGP 261

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767916541 1123 PGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPP-GPVGIPGLKGERGDPGSPG 1183
Cdd:NF038329  262 RGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKdGQNGKDGLPGKDGKDGQPG 323
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 269-557 3.14e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 48.36  E-value: 3.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  269 KGEKGIKGIPGMVGLPGPPGRKGESG----IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKG 344
Cdd:NF038329  119 KGEPGPAGPAGPAGEQGPRGDRGETGpagpAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRG 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  345 DPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDvgppgppgllgrpgeacagmigppgpqgfpglPGLPGEAGI 424
Cdd:NF038329  199 ETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGP--------------------------------DGDPGPTGE 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  425 PGR--PDSAPGKPGKPGSPGLPGAPGLQGLPGSSviycsvGNPGPQGikgkvgppggrgpkgekgneglcacepgpmgpp 502
Cdd:NF038329  247 DGPqgPDGPAGKDGPRGDRGEAGPDGPDGKDGER------GPVGPAG--------------------------------- 287

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767916541  503 gppglpgRQGSKGDLGLPgwlgtkgdpgppGAEGPPGLPGKHGASGPPGNKGAKG 557
Cdd:NF038329  288 -------KDGQNGKDGLP------------GKDGKDGQNGKDGLPGKDGKDGQPG 323
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 1282-1402 1.63e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 46.05  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1282 DGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRipGLPGAPGMRGPEGAMGLP 1361
Cdd:NF038329  179 DGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPD--GDPGPTGEDGPQGPDGPA 256

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 767916541 1362 GMRGPSGPgcKGEPGLDGRRGVDGVPGSPGPPGRKGDTGED 1402
Cdd:NF038329  257 GKDGPRGD--RGEAGPDGPDGKDGERGPVGPAGKDGQNGKD 295
 
Name Accession Description Interval E-value
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1430-1535 1.08e-53

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 460201  Cd Length: 110  Bit Score: 183.18  E-value: 1.08e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  1430 FLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQrNDRSYWLAS 1509
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHTGNGEGHGQDLGSPGSCLERFRTMPFIECNGNGTCNYAS-NDYSYWLST 79

                           90       100       110
                   ....*....|....*....|....*....|.
gi 767916541  1510 AA-----PLPMMPLSEEAIRPYVSRCAVCEA 1535
Cdd:pfam01413   80 VEeqfrkPMSQTPKAGNELRSYISRCVVCEA 110
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1538-1650 9.47e-50

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 460201  Cd Length: 110  Bit Score: 171.62  E-value: 9.47e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  1538 QAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTgAGDQGGGQALMSPGSCLEDFRAAPFLECQGRqGTCHFFANKYSFWLT 1617
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHT-GNGEGHGQDLGSPGSCLERFRTMPFIECNGN-GTCNYASNDYSYWLS 78

                           90       100       110
                   ....*....|....*....|....*....|...
gi 767916541  1618 TVkaDLQFSSaPAPDTLKESQAQRQKISRCQVC 1650
Cdd:pfam01413   79 TV--EEQFRK-PMSQTPKAGNELRSYISRCVVC 108
C4 smart00111
C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of ...
 1429-1536 1.03e-45

C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 128421  Cd Length: 114  Bit Score: 160.25  E-value: 1.03e-45
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541   1429 GFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRNDRSYWLA 1508
Cdd:smart00111    1 GFVIAVHSQTTNVPQCPAGWVELWTGYSFLMHTGNGEGHGQDLGSPGSCLERFRTMPFIECNGRGVCNYASRNDYSFWLS 80

                            90       100       110
                    ....*....|....*....|....*....|....*
gi 767916541   1509 S-------AAPLPMMPLSEEaIRPYVSRCAVCEAP 1536
Cdd:smart00111   81 TiepsdqfTAPRPMTPKAGD-LRPYISRCQVCEKP 114
C4 smart00111
C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of ...
 1537-1652 4.31e-42

C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 128421  Cd Length: 114  Bit Score: 150.23  E-value: 4.31e-42
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541   1537 AQAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTGAGDQGGGQaLMSPGSCLEDFRAAPFLECQGRqGTCHFFANK-YSFW 1615
Cdd:smart00111    1 GFVIAVHSQTTNVPQCPAGWVELWTGYSFLMHTGNGEGHGQD-LGSPGSCLERFRTMPFIECNGR-GVCNYASRNdYSFW 78

                            90       100       110
                    ....*....|....*....|....*....|....*..
gi 767916541   1616 LTTVKADLQFsSAPAPDTLKESQAqRQKISRCQVCVK 1652
Cdd:smart00111   79 LSTIEPSDQF-TAPRPMTPKAGDL-RPYISRCQVCEK 113
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 753-975 1.48e-18

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 90.35  E-value: 1.48e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  753 GCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGM 832
Cdd:NF038329  117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGP 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  833 KGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGfPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRG 912
Cdd:NF038329  197 RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGD-PGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767916541  913 LRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPG 975
Cdd:NF038329  276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 87-347 5.67e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 82.65  E-value: 5.67e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541   87 LSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGfpggrgalgpggplghp 166
Cdd:NF038329  115 GDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAG----------------- 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  167 gekgekgnsvfilgaVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPG 246
Cdd:NF038329  178 ---------------KDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPG 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  247 EVGQQGSPGPTLLveppdfclyKGEKGIKGIPGMVGLPGPPGRKGESGI----GAKGEKGIPGFPGPRGDPGSYGSPGFP 322
Cdd:NF038329  243 PTGEDGPQGPDGP---------AGKDGPRGDRGEAGPDGPDGKDGERGPvgpaGKDGQNGKDGLPGKDGKDGQNGKDGLP 313

                         250       260
                  ....*....|....*....|....*
gi 767916541  323 GLKGELGLVGDPGLFGLIGPKGDPG 347
Cdd:NF038329  314 GKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 640-843 2.05e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 74.56  E-value: 2.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  640 ERGHPGVPGHPGVRGPDGLKGQKGDT-ISCNVTYPGRHGPPGFDGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPgvNG 718
Cdd:NF038329  118 EKGEPGPAGPAGPAGEQGPRGDRGETgPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGP--QG 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  719 QKGIPG-DPAFGHLGPPGKRGLSGVPGIKGPRGDPGcPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGppghscERGAP 797
Cdd:NF038329  196 PRGETGpAGEQGPAGPAGPDGEAGPAGEDGPAGPAG-DGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRG------DRGEA 268

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 767916541  798 GIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPG 843
Cdd:NF038329  269 GPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPG 314
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 566-829 1.95e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 68.39  E-value: 1.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  566 GHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDhedatpggkgfpgplgppgkagpvgPPGLGFPGPPGERGHPG 645
Cdd:NF038329  117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGP-------------------------QGERGEKGPAGPQGEAG 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  646 VPGHPGVRGPDGLKGQKGDTiscnvtypGRHGPPGFDGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGD 725
Cdd:NF038329  172 PQGPAGKDGEAGAKGPAGEK--------GPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGP 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  726 PafGHLGPPGKRGLsgvPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPG---- 801
Cdd:NF038329  244 T--GEDGPQGPDGP---AGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGkdgk 318

                         250       260       270
                  ....*....|....*....|....*....|
gi 767916541  802 --QPGLPGYPGSPGAPGGKGQPGDVGPPGP 829
Cdd:NF038329  319 dgQPGKDGLPGKDGKDGQPGKPAPKTPEVP 348
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 963-1183 1.58e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 55.68  E-value: 1.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  963 GRRGEPGRYGPPGfHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPa 1042
Cdd:NF038329  117 GEKGEPGPAGPAG-PAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQ- 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1043 shfgppgpkgepGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDhGMPGLRGQPGEMGDPGPRGLQGD 1122
Cdd:NF038329  195 ------------GPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPD-GDPGPTGEDGPQGPDGPAGKDGP 261

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767916541 1123 PGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPP-GPVGIPGLKGERGDPGSPG 1183
Cdd:NF038329  262 RGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKdGQNGKDGLPGKDGKDGQPG 323
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 495-826 8.66e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 53.37  E-value: 8.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  495 EPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPD 574
Cdd:NF038329  121 EPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGET 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  575 GPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATpggkgfpgplgppgkagpvgppglgfpgpPGERGHPGVPGHPGVRG 654
Cdd:NF038329  201 GPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQ-----------------------------QGPDGDPGPTGEDGPQG 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  655 PDGLKGQKGdtiscnvtypgrhgppgfdgppgFRGDMGDPGFGGEKgsspvgppgppgspGVNGQKGIPGDPafGHLGPP 734
Cdd:NF038329  252 PDGPAGKDG-----------------------PRGDRGEAGPDGPD--------------GKDGERGPVGPA--GKDGQN 292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  735 GKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGfpgvpgppghsceRGAPGIPGQPGLPGY-PGSPG 813
Cdd:NF038329  293 GKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG-------------KPAPKTPEVPQKPDTaPHTPK 359

                         330
                  ....*....|...
gi 767916541  814 APGGKGQPGDVGP 826
Cdd:NF038329  360 TPQIPGQSKDVTP 372
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 793-844 6.30e-06

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 44.79  E-value: 6.30e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 767916541   793 ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGA 844
Cdd:pfam01391    2 PPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGA 53
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 269-557 3.14e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 48.36  E-value: 3.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  269 KGEKGIKGIPGMVGLPGPPGRKGESG----IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKG 344
Cdd:NF038329  119 KGEPGPAGPAGPAGEQGPRGDRGETGpagpAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRG 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  345 DPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDvgppgppgllgrpgeacagmigppgpqgfpglPGLPGEAGI 424
Cdd:NF038329  199 ETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGP--------------------------------DGDPGPTGE 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  425 PGR--PDSAPGKPGKPGSPGLPGAPGLQGLPGSSviycsvGNPGPQGikgkvgppggrgpkgekgneglcacepgpmgpp 502
Cdd:NF038329  247 DGPqgPDGPAGKDGPRGDRGEAGPDGPDGKDGER------GPVGPAG--------------------------------- 287

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767916541  503 gppglpgRQGSKGDLGLPgwlgtkgdpgppGAEGPPGLPGKHGASGPPGNKGAKG 557
Cdd:NF038329  288 -------KDGQNGKDGLP------------GKDGKDGQNGKDGLPGKDGKDGQPG 323
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 1282-1402 1.63e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 46.05  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1282 DGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRipGLPGAPGMRGPEGAMGLP 1361
Cdd:NF038329  179 DGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPD--GDPGPTGEDGPQGPDGPA 256

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 767916541 1362 GMRGPSGPgcKGEPGLDGRRGVDGVPGSPGPPGRKGDTGED 1402
Cdd:NF038329  257 GKDGPRGD--RGEAGPDGPDGKDGERGPVGPAGKDGQNGKD 295
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 1098-1382 3.78e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 44.90  E-value: 3.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1098 DHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGlhdvgppgPVGIPGLKGERG 1177
Cdd:NF038329  112 QLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAG--------PQGPAGKDGEAG 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1178 DPGSPGisppgprgkkgppgppgSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGD 1257
Cdd:NF038329  184 AKGPAG-----------------EKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGE 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1258 CGLPGPpgppgppgppgykgfpgcDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPgprgepgppadvd 1337
Cdd:NF038329  247 DGPQGP------------------DGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKD------------- 295

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 767916541 1338 dcpripGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLDGRRG 1382
Cdd:NF038329  296 ------GLPGKDGKDGQNGKDGLPGKDGKDGqPGKDGLPGKDGKDG 335
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
732-927 1.58e-03

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 43.09  E-value: 1.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  732 GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGS 811
Cdd:COG5164    10 GPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGGTRPAQNQGSTTPAGNTGGTRPAGNQGATGPAQNQGGTTPAQNQGG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  812 PGAP---GGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPG 888
Cdd:COG5164    90 TRPAgntGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPPGPGSTGPGGSTTPPGDGGSTTPPG 169

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767916541  889 AEGCPGAKGEPGEKGmSGLPGDRGLRGAKGAIGPPGDEG 927
Cdd:COG5164   170 PGGSTTPPDDGGSTT-PPNKGETGTDIPTGGTPRQGPDG 207
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 299-355 2.53e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.47  E-value: 2.53e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767916541   299 GEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPP 355
Cdd:pfam01391    1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
 
Name Accession Description Interval E-value
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1430-1535 1.08e-53

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 460201  Cd Length: 110  Bit Score: 183.18  E-value: 1.08e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  1430 FLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQrNDRSYWLAS 1509
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHTGNGEGHGQDLGSPGSCLERFRTMPFIECNGNGTCNYAS-NDYSYWLST 79

                           90       100       110
                   ....*....|....*....|....*....|.
gi 767916541  1510 AA-----PLPMMPLSEEAIRPYVSRCAVCEA 1535
Cdd:pfam01413   80 VEeqfrkPMSQTPKAGNELRSYISRCVVCEA 110
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1538-1650 9.47e-50

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 460201  Cd Length: 110  Bit Score: 171.62  E-value: 9.47e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  1538 QAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTgAGDQGGGQALMSPGSCLEDFRAAPFLECQGRqGTCHFFANKYSFWLT 1617
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHT-GNGEGHGQDLGSPGSCLERFRTMPFIECNGN-GTCNYASNDYSYWLS 78

                           90       100       110
                   ....*....|....*....|....*....|...
gi 767916541  1618 TVkaDLQFSSaPAPDTLKESQAQRQKISRCQVC 1650
Cdd:pfam01413   79 TV--EEQFRK-PMSQTPKAGNELRSYISRCVVC 108
C4 smart00111
C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of ...
 1429-1536 1.03e-45

C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 128421  Cd Length: 114  Bit Score: 160.25  E-value: 1.03e-45
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541   1429 GFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRNDRSYWLA 1508
Cdd:smart00111    1 GFVIAVHSQTTNVPQCPAGWVELWTGYSFLMHTGNGEGHGQDLGSPGSCLERFRTMPFIECNGRGVCNYASRNDYSFWLS 80

                            90       100       110
                    ....*....|....*....|....*....|....*
gi 767916541   1509 S-------AAPLPMMPLSEEaIRPYVSRCAVCEAP 1536
Cdd:smart00111   81 TiepsdqfTAPRPMTPKAGD-LRPYISRCQVCEKP 114
C4 smart00111
C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of ...
 1537-1652 4.31e-42

C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 128421  Cd Length: 114  Bit Score: 150.23  E-value: 4.31e-42
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541   1537 AQAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTGAGDQGGGQaLMSPGSCLEDFRAAPFLECQGRqGTCHFFANK-YSFW 1615
Cdd:smart00111    1 GFVIAVHSQTTNVPQCPAGWVELWTGYSFLMHTGNGEGHGQD-LGSPGSCLERFRTMPFIECNGR-GVCNYASRNdYSFW 78

                            90       100       110
                    ....*....|....*....|....*....|....*..
gi 767916541   1616 LTTVKADLQFsSAPAPDTLKESQAqRQKISRCQVCVK 1652
Cdd:smart00111   79 LSTIEPSDQF-TAPRPMTPKAGDL-RPYISRCQVCEK 113
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 753-975 1.48e-18

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 90.35  E-value: 1.48e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  753 GCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGM 832
Cdd:NF038329  117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGP 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  833 KGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGfPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRG 912
Cdd:NF038329  197 RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGD-PGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767916541  913 LRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPG 975
Cdd:NF038329  276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 87-347 5.67e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 82.65  E-value: 5.67e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541   87 LSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGfpggrgalgpggplghp 166
Cdd:NF038329  115 GDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAG----------------- 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  167 gekgekgnsvfilgaVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPG 246
Cdd:NF038329  178 ---------------KDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPG 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  247 EVGQQGSPGPTLLveppdfclyKGEKGIKGIPGMVGLPGPPGRKGESGI----GAKGEKGIPGFPGPRGDPGSYGSPGFP 322
Cdd:NF038329  243 PTGEDGPQGPDGP---------AGKDGPRGDRGEAGPDGPDGKDGERGPvgpaGKDGQNGKDGLPGKDGKDGQNGKDGLP 313

                         250       260
                  ....*....|....*....|....*
gi 767916541  323 GLKGELGLVGDPGLFGLIGPKGDPG 347
Cdd:NF038329  314 GKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 640-843 2.05e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 74.56  E-value: 2.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  640 ERGHPGVPGHPGVRGPDGLKGQKGDT-ISCNVTYPGRHGPPGFDGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPgvNG 718
Cdd:NF038329  118 EKGEPGPAGPAGPAGEQGPRGDRGETgPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGP--QG 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  719 QKGIPG-DPAFGHLGPPGKRGLSGVPGIKGPRGDPGcPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGppghscERGAP 797
Cdd:NF038329  196 PRGETGpAGEQGPAGPAGPDGEAGPAGEDGPAGPAG-DGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRG------DRGEA 268

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 767916541  798 GIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPG 843
Cdd:NF038329  269 GPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPG 314
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 566-829 1.95e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 68.39  E-value: 1.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  566 GHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDhedatpggkgfpgplgppgkagpvgPPGLGFPGPPGERGHPG 645
Cdd:NF038329  117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGP-------------------------QGERGEKGPAGPQGEAG 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  646 VPGHPGVRGPDGLKGQKGDTiscnvtypGRHGPPGFDGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGD 725
Cdd:NF038329  172 PQGPAGKDGEAGAKGPAGEK--------GPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGP 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  726 PafGHLGPPGKRGLsgvPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPG---- 801
Cdd:NF038329  244 T--GEDGPQGPDGP---AGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGkdgk 318

                         250       260       270
                  ....*....|....*....|....*....|
gi 767916541  802 --QPGLPGYPGSPGAPGGKGQPGDVGPPGP 829
Cdd:NF038329  319 dgQPGKDGLPGKDGKDGQPGKPAPKTPEVP 348
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 963-1183 1.58e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 55.68  E-value: 1.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  963 GRRGEPGRYGPPGfHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPa 1042
Cdd:NF038329  117 GEKGEPGPAGPAG-PAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQ- 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1043 shfgppgpkgepGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDhGMPGLRGQPGEMGDPGPRGLQGD 1122
Cdd:NF038329  195 ------------GPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPD-GDPGPTGEDGPQGPDGPAGKDGP 261

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767916541 1123 PGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPP-GPVGIPGLKGERGDPGSPG 1183
Cdd:NF038329  262 RGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKdGQNGKDGLPGKDGKDGQPG 323
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 495-826 8.66e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 53.37  E-value: 8.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  495 EPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPD 574
Cdd:NF038329  121 EPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGET 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  575 GPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATpggkgfpgplgppgkagpvgppglgfpgpPGERGHPGVPGHPGVRG 654
Cdd:NF038329  201 GPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQ-----------------------------QGPDGDPGPTGEDGPQG 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  655 PDGLKGQKGdtiscnvtypgrhgppgfdgppgFRGDMGDPGFGGEKgsspvgppgppgspGVNGQKGIPGDPafGHLGPP 734
Cdd:NF038329  252 PDGPAGKDG-----------------------PRGDRGEAGPDGPD--------------GKDGERGPVGPA--GKDGQN 292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  735 GKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGfpgvpgppghsceRGAPGIPGQPGLPGY-PGSPG 813
Cdd:NF038329  293 GKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG-------------KPAPKTPEVPQKPDTaPHTPK 359

                         330
                  ....*....|...
gi 767916541  814 APGGKGQPGDVGP 826
Cdd:NF038329  360 TPQIPGQSKDVTP 372
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 793-844 6.30e-06

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 44.79  E-value: 6.30e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 767916541   793 ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGA 844
Cdd:pfam01391    2 PPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGA 53
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 269-557 3.14e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 48.36  E-value: 3.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  269 KGEKGIKGIPGMVGLPGPPGRKGESG----IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKG 344
Cdd:NF038329  119 KGEPGPAGPAGPAGEQGPRGDRGETGpagpAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRG 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  345 DPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDvgppgppgllgrpgeacagmigppgpqgfpglPGLPGEAGI 424
Cdd:NF038329  199 ETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGP--------------------------------DGDPGPTGE 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  425 PGR--PDSAPGKPGKPGSPGLPGAPGLQGLPGSSviycsvGNPGPQGikgkvgppggrgpkgekgneglcacepgpmgpp 502
Cdd:NF038329  247 DGPqgPDGPAGKDGPRGDRGEAGPDGPDGKDGER------GPVGPAG--------------------------------- 287

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767916541  503 gppglpgRQGSKGDLGLPgwlgtkgdpgppGAEGPPGLPGKHGASGPPGNKGAKG 557
Cdd:NF038329  288 -------KDGQNGKDGLP------------GKDGKDGQNGKDGLPGKDGKDGQPG 323
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 795-844 7.63e-05

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 42.10  E-value: 7.63e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 767916541   795 GAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGA 844
Cdd:pfam01391    1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGA 50
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 1282-1402 1.63e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 46.05  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1282 DGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRipGLPGAPGMRGPEGAMGLP 1361
Cdd:NF038329  179 DGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPD--GDPGPTGEDGPQGPDGPA 256

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 767916541 1362 GMRGPSGPgcKGEPGLDGRRGVDGVPGSPGPPGRKGDTGED 1402
Cdd:NF038329  257 GKDGPRGD--RGEAGPDGPDGKDGERGPVGPAGKDGQNGKD 295
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 1098-1382 3.78e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 44.90  E-value: 3.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1098 DHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGlhdvgppgPVGIPGLKGERG 1177
Cdd:NF038329  112 QLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAG--------PQGPAGKDGEAG 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1178 DPGSPGisppgprgkkgppgppgSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGD 1257
Cdd:NF038329  184 AKGPAG-----------------EKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGE 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541 1258 CGLPGPpgppgppgppgykgfpgcDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPgprgepgppadvd 1337
Cdd:NF038329  247 DGPQGP------------------DGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKD------------- 295

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 767916541 1338 dcpripGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLDGRRG 1382
Cdd:NF038329  296 ------GLPGKDGKDGQNGKDGLPGKDGKDGqPGKDGLPGKDGKDG 335
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
732-927 1.58e-03

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 43.09  E-value: 1.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  732 GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGS 811
Cdd:COG5164    10 GPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGGTRPAQNQGSTTPAGNTGGTRPAGNQGATGPAQNQGGTTPAQNQGG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916541  812 PGAP---GGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPG 888
Cdd:COG5164    90 TRPAgntGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPPGPGSTGPGGSTTPPGDGGSTTPPG 169

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767916541  889 AEGCPGAKGEPGEKGmSGLPGDRGLRGAKGAIGPPGDEG 927
Cdd:COG5164   170 PGGSTTPPDDGGSTT-PPNKGETGTDIPTGGTPRQGPDG 207
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 299-355 2.53e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.47  E-value: 2.53e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767916541   299 GEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPP 355
Cdd:pfam01391    1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 793-836 3.57e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.09  E-value: 3.57e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 767916541   793 ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLP 836
Cdd:pfam01391   14 PPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 878-924 8.50e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 36.32  E-value: 8.50e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 767916541   878 PGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPG 924
Cdd:pfam01391    9 PGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPG 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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