first ubiquitin-like (Ubl) domain located at the N-terminus of coronavirus SARS-CoV non-structural protein 3 (Nsp3) and related proteins; This ubiquitin-like (Ubl) domain (Ubl1) is found at the N-terminus of coronavirus Nsp3, a large multi-functional multi-domain protein which is an essential component of the replication/transcription complex (RTC). The functions of Ubl1 in CoVs are related to single-stranded RNA (ssRNA) binding and to interacting with the nucleocapsid (N) protein. SARS-CoV Ubl1 has been shown to bind ssRNA having AUA patterns, and since the 5'-UTR of the SARS-CoV genome has a number of AUA repeats, it may bind there. In mouse hepatitis virus (MHV), this Ubl1 domain binds the cognate N protein. Adjacent to Ubl1 is a Glu-rich acidic region (also referred to as hypervariable region, HVR); Ubl1 together with HVR has been called Nsp3a. Currently, the function of HVR in CoVs is unknown. This model corresponds to one of two Ubl domains in Nsp3; the other is located N-terminal to the papain-like protease (PLpro) and is not represented by this model.

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  17 KSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIESGGNYVAGGPEAFKK 96
Cdd:cd17149    1 KNVLVYRNGDPFYAGRRLVINEKRVSSFEVFLKEVTGGVQAPFGAVRNIYTPRGGHRVRSLEQLQSGEQYVAAGRERFKK 80

3-hydroxybenzoate 6-monooxygenase;

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  69 RTGHRIRKLDQIESGGNYVAG---GPEAFKKLNYLDIGEIKKRP---------MEAVNTEVkpVIhsRINVSARFRKSLH 136
Cdd:PRK08163  25 RQGIKVKLLEQAAEIGEIGAGiqlGPNAFSALDALGVGEAARQRavftdhltmMDAVDAEE--VV--RIPTGQAFRARFG 100

                 ..
gi 755544167 137 EP 138
Cdd:PRK08163 101 NP 102

Dublecortin-like domain 1 found in doublecortin domain-containing protein 2 (DCDC2); DCDC2 is a member of doublecortin (DCX) family. It is a microtubule-associated protein (MAP) with a stable ubiquitin-like tertiary fold. Ubiquitin (Ub) is a protein modifier in eukaryotes that is involved in various cellular processes, including transcriptional regulation, cell cycle control, and DNA repair. Microtubules are key components of the cytoskeleton that are involved in cell movement, shape determination, division and transport. DCDC2 genetic variation in humans is associated with reading disability, attention deficit hyperactivity disorder (ADHD), and difficulties in mathematics. A genetic variant of DCDC2 associates with dyslexia, a common neurobehavioral disorder of reading. DCDC2 protein interacts with many of the same cytoskeleton related proteins that other members of the DCX family interact with.

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  17 KSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIESGGNYVAGGPEAFKK 96
Cdd:cd17149    1 KNVLVYRNGDPFYAGRRLVINEKRVSSFEVFLKEVTGGVQAPFGAVRNIYTPRGGHRVRSLEQLQSGEQYVAAGRERFKK 80

Domain in the Doublecortin (DCX) gene product; Tandemly-repeated domain in doublin, the Doublecortin gene product. Proposed to bind tubulin. Doublecortin (DCX) is mutated in human X-linked neuronal migration defects.

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167   134 SLHEPCTIFLIANGDLISPASRLLIPKKALNQWDHVLQMVTEKITLRSG-AVHRLYTLEGKLVESGAELENGQFYVAVGR 212
Cdd:smart00537   1 SLVKPKRIRFYRNGDRFFKGVRLVVNRKRFKSFEALLQDLTEVVKLDLPhGVRKLYTLDGKKVTSLDELEDGGSYVASGT 80

                   ....*....
gi 755544167   213 DKFKRLPYS 221
Cdd:smart00537  81 EAFKKVDYG 89

Doublecortin;

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755544167   35 VIHEKKVSSFDVFLKEVTGGVQ-APFGAVRNIYTPRtGHRIRKLDQIESGGNYVAGGPEAF 94
Cdd:pfam03607   1 VVNKRRFRSFDALLDELTEKVVkLPFGAVRKLYTLD-GKRVTSLDELEDGGVYVAAGREKF 60

MAEBL; Provisional

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  335 RGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKTSKDANQKedfsAMNGETEDRGGSKAAGTSEQEEGIPDHGEKKASP 414
Cdd:PTZ00121 1385 KKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKK----AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAE 1460

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755544167  415 SRVNGGTDEENGEELDQVAEELQSTEDEKGKAEGDNSGQDEAGLDAQRPPRPEVTVTSPQENEENEANKASSA 487
Cdd:PTZ00121 1461 EAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA 1533

Dublecortin-like domain 1 found in doublecortin domain-containing protein 2 (DCDC2); DCDC2 is a member of doublecortin (DCX) family. It is a microtubule-associated protein (MAP) with a stable ubiquitin-like tertiary fold. Ubiquitin (Ub) is a protein modifier in eukaryotes that is involved in various cellular processes, including transcriptional regulation, cell cycle control, and DNA repair. Microtubules are key components of the cytoskeleton that are involved in cell movement, shape determination, division and transport. DCDC2 genetic variation in humans is associated with reading disability, attention deficit hyperactivity disorder (ADHD), and difficulties in mathematics. A genetic variant of DCDC2 associates with dyslexia, a common neurobehavioral disorder of reading. DCDC2 protein interacts with many of the same cytoskeleton related proteins that other members of the DCX family interact with.

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  17 KSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIESGGNYVAGGPEAFKK 96
Cdd:cd17149    1 KNVLVYRNGDPFYAGRRLVINEKRVSSFEVFLKEVTGGVQAPFGAVRNIYTPRGGHRVRSLEQLQSGEQYVAAGRERFKK 80

Doublecortin-like domain 2 found in doublecortin domain-containing protein 2 (DCDC2); DCDC2 is a member of the doublecortin (DCX) family. It is a microtubule-associated protein (MAP) with stable double tandem DCX repeats of a ubiquitin-like tertiary fold. Ubiquitin (Ub) is a protein modifier in eukaryotes that is involved in various cellular processes including transcriptional regulation, cell cycle control, and DNA repair. Microtubules are key components of cytoskeleton that are involved in cell movement, shape determination, division and transport. DCDC2 genetic variation in humans is associated with reading disability, attention deficit hyperactivity disorder (ADHD), and difficulties in mathematics. A genetic variant of DCDC2 associates with dyslexia, a common neurobehavioral disorder of reading. DCDC2 protein interacts with many of the same cytoskeleton related proteins that other members of the DCX family interact with.

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755544167 138 PCTIFLIANGDLISPASRLLIPKKALNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELENGQFYVAVG 211
Cdd:cd16113    1 PKTIHVFPNGDLLHPPSKVLLTKRRLPNWDTVLEEVTEKVKLQTGAVRKLYTLDGKRISDPDELVNGGQYVAVG 74

Domain in the Doublecortin (DCX) gene product; Tandemly-repeated domain in doublin, the Doublecortin gene product. Proposed to bind tubulin. Doublecortin (DCX) is mutated in human X-linked neuronal migration defects.

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167    12 SQPVVKSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTG--GVQAPFGaVRNIYTPRtGHRIRKLDQIESGGNYVAG 89
Cdd:smart00537   1 SLVKPKRIRFYRNGDRFFKGVRLVVNRKRFKSFEALLQDLTEvvKLDLPHG-VRKLYTLD-GKKVTSLDELEDGGSYVAS 78

                           90
                   ....*....|.
gi 755544167    90 GPEAFKKLNYL 100
Cdd:smart00537  79 GTEAFKKVDYG 89

Dublecortin-like domain 1 found in doublecortin domain-containing protein 2C (DCDC2C); DCDC2 is a member of doublecortin (DCX) family. It is a microtubule-associated protein (MAP) with stable double tandem DCX repeats of ubiquitin-like tertiary fold. Microtubules are key components of the cytoskeleton that are involved in cell movement, shape determination, division and transport. DCDC2 genetic variation in humans is associated with reading disability, attention deficit hyperactivity disorder (ADHD), and difficulties in mathematics. A genetic variant of DCDC2 associates with dyslexia, a common neurobehavioral disorder of reading. DCDC2 protein interacts with many of the same cytoskeleton related proteins that other members of the DCX family interact with.

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  17 KSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGaVRNIYTPRTGHRIRKLDQIESGGNYVAGGPEAFKK 96
Cdd:cd17151    1 KTILVYRNGDPFYQAHKVVIHRRRVKTFDALLRQLTETVKVPFG-VRCLYTPRNGHRVKGLDDLQGGGKYVAAGRERFKK 79

Doublecortin-like domain 2 found in doublecortin domain-containing protein 2C (DCDC2C); DCDC2 is a member of the doublecortin (DCX) family. It is a microtubule-associated protein (MAP) with stable double tandem DCX repeats of a ubiquitin-like tertiary fold. Microtubules are key components of cytoskeleton that are involved in cell movement, shape determination, division and transport. DCDC2 genetic variation in humans is associated with reading disability, attention deficit hyperactivity disorder (ADHD), and difficulties in mathematics. A genetic variant of DCDC2 associates with dyslexia, a common neurobehavioral disorder of reading. DCDC2 protein interacts with many of the same cytoskeleton related proteins that other members of the DCX family interact with.

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755544167 138 PCTIFLIANGDLISPASRLLIPKKALNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFK 216
Cdd:cd17154    1 SRTINVFTNGEVLVPPAKIIIPKFTLRSWENVLAMITEKAFLRTGGVFRLCTLNGHPVSDSTELEDNHYYVAVGSEKFK 79

Dublecortin-like domain structurally similar to a beta-grasp ubiquitin-like fold; Dublecortin (DCX) is a microtubule-associated protein (MAP) with a stable ubiquitin-like tertiary fold. Ubiquitin (Ub) is a protein modifier in eukaryotes that is involved in various cellular processes, including transcriptional regulation, cell cycle control, and DNA repair. Microtubules are key components of the cytoskeleton that are involved in cell movement, shape determination, division and transport. The DCX gene family consists of eleven paralogs in human and mouse, and its DCX protein domains can occur in double tandem or as single DCX repeats. Proteins with DCX tandem domains in general have roles in microtubule (MT) regulation and signal transduction such as X-linked doublecortin (DCX), retinitis pigmentosa-1 (RP1) and doublecortin-like kinase (DCLK). Single DCX repeat proteins are normally localized to actin-rich subcellular structures, or the nucleus such as DCDC2. DCX is not only a unique MAP in terms of structure, it also interacts with multiple additional proteins. Mutations in human DCX genes are associated with abnormal neuronal migration, epilepsy, and mental retardation.

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755544167  17 KSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGAVRNIYTPRtGHRIRKLDQIESGGNYVAGG 90
Cdd:cd01617    1 KRITVFRNGDKNFKGVKVLVKPRRFRTFDQLLDELTEKLGLPTGGVRKLYTPS-GKLVKSLSDLEDGESYVVCG 73

Doublecortin;

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755544167   35 VIHEKKVSSFDVFLKEVTGGVQ-APFGAVRNIYTPRtGHRIRKLDQIESGGNYVAGGPEAF 94
Cdd:pfam03607   1 VVNKRRFRSFDALLDELTEKVVkLPFGAVRKLYTLD-GKRVTSLDELEDGGVYVAAGREKF 60

Doublecortin-like domain 1 found in retinitis pigmentosa 1-like 1 (RP1L1) protein; RP1L1 is a member of the doublecortin (DCX) family. Its DCX domains occur in double tandem repeats. DCX is a microtubule-associated protein (MAP) with a stable ubiquitin-like tertiary fold. Microtubules are key components of cytoskeleton that are involved in cell movement, shape determination, division and transport. The DCX-domain of RP1L1 localizes to the photoreceptor and is genetically associated with retinitis pigmentosa.

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755544167  17 KSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGaVRNIYTPRTGHRIRKLDQIESGGNYV 87
Cdd:cd17146    1 KKITFYKSGDPQFGGVKMAVNKRTFKSFSALLDDLSQRVPLPFG-VRTITTPRGTHSISRLEQLEDGGCYL 70

Dublecortin-like domain 1; Members of the doublecortin (DCX) gene family are microtubule-associated proteins (MAPs). Microtubules are key components of cytoskeleton that are involved in cell movement, shape determination, division and transport. The DCX gene family consists of eleven paralogs in human and mouse, and its protein domains can occur in double tandem or single repeats. The family represents the first repeat of the DCX domain which has a stable ubiquitin-like tertiary fold. Proteins with DCX double tandem domains in general have roles in microtubule (MT) regulation and signal transduction such as X-linked doublecortin (DCX), retinitis pigmentosa-1 (RP1) and doublecortin-like kinase (DCLK).

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  17 KSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVT----GGVQAPFGaVRNIYTPRTGHRIRKLDQIESGGNYVAGGPE 92
Cdd:cd16109    3 KKVRFYRNGDRFFKGIVYAVSSERFRSFEALLADLTrslsDNVNLPQG-VRTIFTIDGSRKITSLDELEDGESYVCASTD 81

                 ....
gi 755544167  93 AFKK 96
Cdd:cd16109   82 AFKK 85

Dublecortin-like domain 1 found in neuronal migration protein doublecortin (DCX); DCX, also termed doublin or lissencephalin-X (Lis-XDCX), is a microtubule-associated protein (MAP). It belongs to the doublecortin (DCX) family, has double tandem DCX repeats, and is expressed in migrating neurons. Structure studies show that the N-terminal DCX domain has a stable ubiquitin-like fold. DCX is not only a unique MAP in terms of structure, it also interacts with multiple additional proteins. Mutations in the human DCX genes are associated with abnormal neuronal migration, epilepsy, and mental retardation.

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  17 KSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVT----GGVQAPFGaVRNIYTPRTGHRIRKLDQIESGGNYVAGGPE 92
Cdd:cd16112    3 KKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTrslsDNINLPQG-VRYIYTIDGSRKIGSMDELEEGESYVCSSDN 81

                 ....*..
gi 755544167  93 AFKKLNY 99
Cdd:cd16112   82 FFKKVEY 88

Dublecortin-like domain 1 found in doublecortin-like kinase 2 (DCLK2); DCLK2 is a member of doublecortin (DCX) protein superfamily that functions as a microtubule-associated protein (MAP), and contains two conserved tubulin binding domains, which typically occur in tandem. The DCX domain has a stable ubiquitin-like tertiary fold. Ubiquitin (Ub) is a protein modifier (Ubiquitination) in eukaryotes that is involved in various cellular processes including transcriptional regulation, cell cycle control, and DNA repair. In addition to microtubule binding domains, DCLK encodes a serine/threonine kinase-domain that is similar to Ca/calmodulin-dependent (Cam) protein kinases. Molecular actions of DCX members are less well characterized and it shows that DCLK2 members regulate cyclic AMP signaling. Unlike DCX, this DCLK has varying levels of expression throughout embryonic and adult life.

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  17 KSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVT----GGVQAPFGaVRNIYTPRTGHRIRKLDQIESGGNYVAGGPE 92
Cdd:cd17141    3 KKVRFYRNGDRYFKGLVYAVSSDRFRSFDALLMELTrslsDNVNLPQG-VRTIYTIDGSKKITSLDELLEGESYVCASNE 81

                 ....
gi 755544167  93 AFKK 96
Cdd:cd17141   82 PFRK 85

Dublecortin-like domain 2 found in retinitis pigmentosa 1 (RP1)-like protein; RP1, also termed oxygen-regulated protein 1, is a member of doublecortin (DCX) superfamily that contains double tandem repeats of the DCX domains. RP1 is associated with retinitis pigmentosa, which is a type of inherited blindness. DCX is a microtubule-associated protein (MAP) with a stable ubiquitin-like tertiary fold. Microtubules are key components of cytoskeleton that are involved in cell movement, shape determination, division and transport. The RP1 protein is expressed in photoreceptors that is required for correct stacking of outer segment discs. RP1 protein interacts with many of the same cytoskeleton related proteins that other members of the DCX family interact with.

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  17 KSVLVYRNGDPFFAgRRVVIHEKKVSSFDVFLKEVTGGVQAPfgaVRNIYTPrTGHRIRKLDQ-IESGGNYVAGGPEAFK 95
Cdd:cd17147    1 RKLIVFKNGDPGFK-HTLILNKKTTQSFEALLDHVSELMQFP---VVKLYTT-DGRRVDSLQAlILSSGAVVAAGREPFK 75

Dublecortin-like domain 2 found in neuronal migration protein doublecortin (DCX); DCX, also termed doublin or lissencephalin-X (Lis-XDCX), is a microtubule-associated protein (MAP). It belongs to the doublecortin (DCX) family, has double tandem DCX repeats, and is expressed in migrating neurons. Structure studies show that the N-terminal DCX domain has a stable ubiquitin-like fold. DCX is not only a unique MAP in terms of its structure, but also interacts with multiple additional proteins. Mutations in the human DCX genes are associated with abnormal neuronal migration, epilepsy, and mental retardation.

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167 138 PCTIFLIANGDLISPASRLLIPKKALNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAE-LENGQFYVAVGRDKFK 216
Cdd:cd17142    4 PKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDfFGDDDVFIACGPEKFR 83

Dublecortin-like domain 2 found in retinitis pigmentosa (RP)-like protein; RP-like protein family is part of doublecortin (DCX) superfamily with double tandem DCX repeats that are associated with retinitis pigmentosa. DCX is a microtubule-associated protein (MAP) with a stable ubiquitin-like tertiary fold. Microtubules are key components of cytoskeleton that are involved in cell movement, shape determination, division and transport. RP-like proteins are colocalized to the photoreceptor and share a function in outer segment disc morphogenesis.

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755544167  17 KSVLVYRNGDPfFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPfgaVRNIYTpRTGHRIRKLDQI 80
Cdd:cd17070    1 KVITVISNGDP-HSRHTILLNRRTTQSFEQVLQDLSELLKGP---VRKLYT-TDGKKVESLSAL 59

Doublecortin-like domain 2 found in doublecortin domain-containing protein 2C (DCDC2C); DCDC2 is a member of the doublecortin (DCX) family. It is a microtubule-associated protein (MAP) with stable double tandem DCX repeats of a ubiquitin-like tertiary fold. Microtubules are key components of cytoskeleton that are involved in cell movement, shape determination, division and transport. DCDC2 genetic variation in humans is associated with reading disability, attention deficit hyperactivity disorder (ADHD), and difficulties in mathematics. A genetic variant of DCDC2 associates with dyslexia, a common neurobehavioral disorder of reading. DCDC2 protein interacts with many of the same cytoskeleton related proteins that other members of the DCX family interact with.

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755544167  21 VYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGAVRNIYTpRTGHRIRKLDQIESGGNYVAGGPEAFK 95
Cdd:cd17154    6 VFTNGEVLVPPAKIIIPKFTLRSWENVLAMITEKAFLRTGGVFRLCT-LNGHPVSDSTELEDNHYYVAVGSEKFK 79

Dublecortin-like domain 2 found in retinitis pigmentosa (RP)-like protein; RP-like protein family is part of doublecortin (DCX) superfamily with double tandem DCX repeats that are associated with retinitis pigmentosa. DCX is a microtubule-associated protein (MAP) with a stable ubiquitin-like tertiary fold. Microtubules are key components of cytoskeleton that are involved in cell movement, shape determination, division and transport. RP-like proteins are colocalized to the photoreceptor and share a function in outer segment disc morphogenesis.

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755544167 141 IFLIANGDlisPASR--LLIPKKALNQWDHVLQMVTEkiTLRsGAVHRLYTLEGKLVESGAELENGQ--FYVA 209
Cdd:cd17070    3 ITVISNGD---PHSRhtILLNRRTTQSFEQVLQDLSE--LLK-GPVRKLYTTDGKKVESLSALFHGPdeYVAA 69

transcription termination factor Rho; Provisional

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167 327 AGAERSETRGAAevqEDEDTQVEVPVDQRPAEIVDEEEDGEKTSKDANQKEDfsamNGETEDRGGSKAAGTSEQEEGIPD 406
Cdd:PRK12678 105 APAARAAAAAAA---EAASAPEAAQARERRERGEAARRGAARKAGEGGEQPA----TEARADAAERTEEEERDERRRRGD 177

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755544167 407 HGEKKASPSRVNGGTDEENGEELDQVAEELQSTEDEKGKAEGDNSGQDEAGLDAQRPPRPE 467
Cdd:PRK12678 178 REDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDA 238

3-hydroxybenzoate 6-monooxygenase;

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755544167  69 RTGHRIRKLDQIESGGNYVAG---GPEAFKKLNYLDIGEIKKRP---------MEAVNTEVkpVIhsRINVSARFRKSLH 136
Cdd:PRK08163  25 RQGIKVKLLEQAAEIGEIGAGiqlGPNAFSALDALGVGEAARQRavftdhltmMDAVDAEE--VV--RIPTGQAFRARFG 100

                 ..
gi 755544167 137 EP 138
Cdd:PRK08163 101 NP 102