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Conserved domains on  [gi|755534236|ref|XP_011241684|]
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pericentrin isoform X4 [Mus musculus]

Protein Classification

Smc and PACT_coil_coil domain-containing protein( domain architecture ID 13382013)

Smc and PACT_coil_coil domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 2797-2875 1.52e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


:

Pssm-ID: 463115  Cd Length: 77  Bit Score: 104.98  E-value: 1.52e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755534236  2797 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKitmSRPFTKFRTAVRVVIAVLRLRFLVKKW 2875
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS---RKPRRKLKSAALAVIAIARMKRLAREW 77
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1087-1662 2.08e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 2.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1087 QQELLERLREESAAKDRLA-LELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKS 1165
Cdd:COG1196   219 KEELKELEAELLLLKLRELeAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1166 VLWNQKETLTNEAKEREAALQEEVESLTRVQwESRKQSEKDRATLLSQMRVLESELEDQLvqhrgcAQLAEEVATLKQQL 1245
Cdd:COG1196   299 RLEQDIARLEERRRELEERLEELEEELAELE-EELEELEEELEELEEELEEAEEELEEAE------AELAEAEEALLEAE 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1246 AALDKHLRSQRQFmDDQAAEREHEREEFQQEIQRLEGQLRQAARprppgprdsQCVQLDEEVELLQEKLREKLDGFNELV 1325
Cdd:COG1196   372 AELAEAEEELEEL-AEELLEALRAAAELAAQLEELEEAEEALLE---------RLERLEEELEELEEALAELEEEEEEEE 441

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1326 IKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGD--LLLTTVSRSGLDEAGCP 1403
Cdd:COG1196   442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADyeGFLEGVKAALLLAGLRG 521

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1404 MLPQGSSSRGPEAQPDVTERALLqhENEVVHRRNSEIDELKSLIENLQEN-------------QRQLQKDKAEEIEQLHE 1470
Cdd:COG1196   522 LAGAVAVLIGVEAAYEAALEAAL--AAALQNIVVEDDEVAAAAIEYLKAAkagratflpldkiRARAALAAALARGAIGA 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1471 VIEKLQSELSLMGPKVHEVSDPQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVF--GQLLADQAHGHSQALEALQQ 1548
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSagGSLTGGSRRELLAALLEAEA 679

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1549 RLQDAEEVAARHLAELEHcVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLEIDAvnkwkvshsleleAILLALAHFR 1628
Cdd:COG1196   680 ELEELAERLAEEELELEE-ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE-------------ELLEELLEEE 745

                         570       580       590
                  ....*....|....*....|....*....|....
gi 755534236 1629 HALEQQTCATPDEPPELRQLRVQCARLSHQLQVL 1662
Cdd:COG1196   746 ELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 118-584 1.18e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 1.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  118 LELEALRLSLNNMHTAQLELTQA-NLQKEKETALTELREMLNGRRAQELALLQSRQQcELELLREQHAREKEEMAlrsgq 196
Cdd:COG1196   281 LELEEAQAEEYELLAELARLEQDiARLEERRRELEERLEELEEELAELEEELEELEE-ELEELEEELEEAEEELE----- 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  197 EAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQsemeglQSQFQKELSEQKVELEKIFQAKHEAEV 276
Cdd:COG1196   355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ------LEELEEAEEALLERLERLEEELEELEE 428

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  277 SLKNLEAQHQAAIKKLQEDLQSEhcQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLEsMKTNREE 356
Cdd:COG1196   429 ALAELEEEEEEEEEALEEAAEEE--AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE-AEADYEG 505

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  357 LNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLEST 436
Cdd:COG1196   506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR 585

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  437 EISSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAEER 516
Cdd:COG1196   586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755534236  517 LASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDLL 584
Cdd:COG1196   666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 483-1157 4.17e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 4.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  483 KAEEKIQQMKEEFQK---KEAEWELSREELKREAE--ERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQI 557
Cdd:COG1196   176 EAERKLEATEENLERledILGELERQLEPLERQAEkaERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  558 LDLERSLMEQQGHLRQLEQELTRDDLlpcsqcgqepamaQEEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAKEQ 637
Cdd:COG1196   256 EELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  638 DAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKR-HL 716
Cdd:COG1196   323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAaQL 402

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  717 SNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQKKEScHREMLTQELENLKRQHAEELQSVRDSLRMEMSAQHIEN 796
Cdd:COG1196   403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  797 GKGPAADLQGAHQQQDPAMALHNEGhllvEDGDAVLRSVDAEGLLHQAGPQELGDAHTVEMQKSQAELAKPQELQASQDQ 876
Cdd:COG1196   482 LLEELAEAAARLLLLLEAEADYEGF----LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  877 VAQVRDKvFLLNRELEecRAELEQLQQRRERENQEgttlicmlRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKS 956
Cdd:COG1196   558 VAAAAIE-YLKAAKAG--RATFLPLDKIRARAALA--------AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT 626

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  957 RISERAGLLLDHEDAADTSDARLAAAALGdmwsdeglleidrtlpegaetssvceisshvcesffispentldceqpirr 1036
Cdd:COG1196   627 LVAARLEAALRRAVTLAGRLREVTLEGEG--------------------------------------------------- 655

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1037 VYQSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLE 1116
Cdd:COG1196   656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE 735

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|.
gi 755534236 1117 GFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAAREL 1157
Cdd:COG1196   736 ELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2203-2557 9.99e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 9.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2203 RRQVELLAYKVEQEKCIANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRyg 2282
Cdd:COG1196   224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE-- 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2283 hvtwsycgtssasAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNN 2362
Cdd:COG1196   302 -------------QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2363 QLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQ 2442
Cdd:COG1196   369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2443 ETQVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQErcVELRREKEVSGNLRSAVDALRTHKQELGC-CL 2521
Cdd:COG1196   449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL--LLLEAEADYEGFLEGVKAALLLAGLRGLAgAV 526

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 755534236 2522 QREREKAAWLQAELEQLSARVKEQEARKDARRMERR 2557
Cdd:COG1196   527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 2797-2875 1.52e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 104.98  E-value: 1.52e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755534236  2797 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKitmSRPFTKFRTAVRVVIAVLRLRFLVKKW 2875
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS---RKPRRKLKSAALAVIAIARMKRLAREW 77
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1087-1662 2.08e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 2.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1087 QQELLERLREESAAKDRLA-LELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKS 1165
Cdd:COG1196   219 KEELKELEAELLLLKLRELeAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1166 VLWNQKETLTNEAKEREAALQEEVESLTRVQwESRKQSEKDRATLLSQMRVLESELEDQLvqhrgcAQLAEEVATLKQQL 1245
Cdd:COG1196   299 RLEQDIARLEERRRELEERLEELEEELAELE-EELEELEEELEELEEELEEAEEELEEAE------AELAEAEEALLEAE 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1246 AALDKHLRSQRQFmDDQAAEREHEREEFQQEIQRLEGQLRQAARprppgprdsQCVQLDEEVELLQEKLREKLDGFNELV 1325
Cdd:COG1196   372 AELAEAEEELEEL-AEELLEALRAAAELAAQLEELEEAEEALLE---------RLERLEEELEELEEALAELEEEEEEEE 441

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1326 IKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGD--LLLTTVSRSGLDEAGCP 1403
Cdd:COG1196   442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADyeGFLEGVKAALLLAGLRG 521

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1404 MLPQGSSSRGPEAQPDVTERALLqhENEVVHRRNSEIDELKSLIENLQEN-------------QRQLQKDKAEEIEQLHE 1470
Cdd:COG1196   522 LAGAVAVLIGVEAAYEAALEAAL--AAALQNIVVEDDEVAAAAIEYLKAAkagratflpldkiRARAALAAALARGAIGA 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1471 VIEKLQSELSLMGPKVHEVSDPQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVF--GQLLADQAHGHSQALEALQQ 1548
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSagGSLTGGSRRELLAALLEAEA 679

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1549 RLQDAEEVAARHLAELEHcVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLEIDAvnkwkvshsleleAILLALAHFR 1628
Cdd:COG1196   680 ELEELAERLAEEELELEE-ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE-------------ELLEELLEEE 745

                         570       580       590
                  ....*....|....*....|....*....|....
gi 755534236 1629 HALEQQTCATPDEPPELRQLRVQCARLSHQLQVL 1662
Cdd:COG1196   746 ELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 118-584 1.18e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 1.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  118 LELEALRLSLNNMHTAQLELTQA-NLQKEKETALTELREMLNGRRAQELALLQSRQQcELELLREQHAREKEEMAlrsgq 196
Cdd:COG1196   281 LELEEAQAEEYELLAELARLEQDiARLEERRRELEERLEELEEELAELEEELEELEE-ELEELEEELEEAEEELE----- 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  197 EAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQsemeglQSQFQKELSEQKVELEKIFQAKHEAEV 276
Cdd:COG1196   355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ------LEELEEAEEALLERLERLEEELEELEE 428

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  277 SLKNLEAQHQAAIKKLQEDLQSEhcQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLEsMKTNREE 356
Cdd:COG1196   429 ALAELEEEEEEEEEALEEAAEEE--AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE-AEADYEG 505

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  357 LNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLEST 436
Cdd:COG1196   506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR 585

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  437 EISSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAEER 516
Cdd:COG1196   586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755534236  517 LASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDLL 584
Cdd:COG1196   666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733
PTZ00121 PTZ00121
MAEBL; Provisional
 133-647 3.32e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 3.32e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  133 AQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEM-------------ALRSGQEAA 199
Cdd:PTZ00121 1263 AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAkkkaeeakkkadaAKKKAEEAK 1342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  200 ELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKELSEQKVELE----------KIFQ 269
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADelkkaaaakkKADE 1422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  270 AKHEAEVSLKNLEAQHQAAIKKLQEDLQ--SEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQL 347
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKKADEAKkkAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  348 ---ESMKTNREELNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR 424
Cdd:PTZ00121 1503 kkaAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK 1582

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  425 LQEAREdsLESTEISSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQV---------------KLSKAEEKIQ 489
Cdd:PTZ00121 1583 AEEAKK--AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVeqlkkkeaeekkkaeELKKAEEENK 1660

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  490 QMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISRFEHRESsmrhlqdQQAAQILDLERSLMEQQG 569
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK-------KKAEELKKAEEENKIKAE 1733

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755534236  570 HLRQLEQELTRDdllpcsqcGQEPAMAQEEKNGALLREKEDCAlqllmAQNRFLEERKEIMEKFAKEQDAFLRDAQEK 647
Cdd:PTZ00121 1734 EAKKEAEEDKKK--------AEEAKKDEEEKKKIAHLKKEEEK-----KAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1069-1387 4.11e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 4.11e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1069 VEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQlilELEDLRK 1148
Cdd:TIGR02169  668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE---RLEELEE 744

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1149 QLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQS----EKDRATLLSQMRVLESELEDQ 1224
Cdd:TIGR02169  745 DLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAElsklEEEVSRIEARLREIEQKLNRL 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1225 lvqHRGCAQLAEEVATLKQQLAALDkhlrSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAarprppgprDSQCVQLD 1304
Cdd:TIGR02169  825 ---TLEKEYLEKEIQELQEQRIDLK----EQIKSIEKEIENLNGKKEELEEELEELEAALRDL---------ESRLGDLK 888

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1305 EEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEkQKKSMEELKEKEILKQENM 1384
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPE-EELSLEDVQAELQRVEEEI 967


                   ...
gi 755534236  1385 GDL 1387
Cdd:TIGR02169  968 RAL 970
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 483-1157 4.17e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 4.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  483 KAEEKIQQMKEEFQK---KEAEWELSREELKREAE--ERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQI 557
Cdd:COG1196   176 EAERKLEATEENLERledILGELERQLEPLERQAEkaERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  558 LDLERSLMEQQGHLRQLEQELTRDDLlpcsqcgqepamaQEEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAKEQ 637
Cdd:COG1196   256 EELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  638 DAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKR-HL 716
Cdd:COG1196   323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAaQL 402

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  717 SNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQKKEScHREMLTQELENLKRQHAEELQSVRDSLRMEMSAQHIEN 796
Cdd:COG1196   403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  797 GKGPAADLQGAHQQQDPAMALHNEGhllvEDGDAVLRSVDAEGLLHQAGPQELGDAHTVEMQKSQAELAKPQELQASQDQ 876
Cdd:COG1196   482 LLEELAEAAARLLLLLEAEADYEGF----LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  877 VAQVRDKvFLLNRELEecRAELEQLQQRRERENQEgttlicmlRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKS 956
Cdd:COG1196   558 VAAAAIE-YLKAAKAG--RATFLPLDKIRARAALA--------AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT 626

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  957 RISERAGLLLDHEDAADTSDARLAAAALGdmwsdeglleidrtlpegaetssvceisshvcesffispentldceqpirr 1036
Cdd:COG1196   627 LVAARLEAALRRAVTLAGRLREVTLEGEG--------------------------------------------------- 655

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1037 VYQSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLE 1116
Cdd:COG1196   656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE 735

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|.
gi 755534236 1117 GFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAAREL 1157
Cdd:COG1196   736 ELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 669-1479 1.34e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 1.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   669 ELETKHRSELTEQLASSESRRQALLEThVAELQVKHNAEISALEKRHlsnldelescyvADVQTIRDEHQQALELLRAEL 748
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEE-LKEAEEELEELTAELQELE------------EKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   749 EEQLQKKEschremLTQELENLKRQHAEELQSVRDSLRmEMSAQHIENGKGPAADLQGAHQQQDPAMALHNEghllvedg 828
Cdd:TIGR02168  288 KELYALAN------EISRLEQQKQILRERLANLERQLE-ELEAQLEELESKLDELAEELAELEEKLEELKEE-------- 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   829 davlrsvdaegllHQAGPQELGDAHTVEMQKSQAELAKPQELQASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRERE 908
Cdd:TIGR02168  353 -------------LESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   909 NQEGTTLIC-MLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGLLLDHEDAADTSDARLAAAalgdm 987
Cdd:TIGR02168  420 QQEIEELLKkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL----- 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   988 wsdEGLLEIDRTLPEG--AETSSVCEISSHV-CESFFISPENTLDceqpirrvyQSLSTAVEGLLEMALDSSKQ------ 1058
Cdd:TIGR02168  495 ---ERLQENLEGFSEGvkALLKNQSGLSGILgVLSELISVDEGYE---------AAIEAALGGRLQAVVVENLNaakkai 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1059 --LEEARQ-------LHRCVEREFRHRNEEMAQAMQKQQELLERLrEESAAKDRLALElhtakGLLEGFKVEKvDLQEAL 1129
Cdd:TIGR02168  563 afLKQNELgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDL-VKFDPKLRKALS-----YLLGGVLVVD-DLDNAL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1130 G-KKEESEQQLILELED--------LRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEeveslTRVQWESR 1200
Cdd:TIGR02168  636 ElAKKLRPGYRIVTLDGdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE-----LRKELEEL 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1201 KQSEKDRATLLSQMRVLESELEDQLVQHRG-CAQLAEEVATLKQQLAALDKhlrsQRQFMDDQAAEREHEREEFQQEIQR 1279
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALRKDLARLEAeVEQLEERIAQLSKELTELEA----EIEELEERLEEAEEELAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1280 LEGQLRQAARprppgprdsQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQL 1359
Cdd:TIGR02168  787 LEAQIEQLKE---------ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1360 QEELEKQKKSMEELKEK-EILKQENMGDLLLTTVSRSGLDEAgcpmlpqgSSSRGPEAQPDVTERALLQHENEVVHRRNS 1438
Cdd:TIGR02168  858 AAEIEELEELIEELESElEALLNERASLEEALALLRSELEEL--------SEELRELESKRSELRRELEELREKLAQLEL 929

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 755534236  1439 EIDELKSLIENLQENQRQLQKDKAEEIEQLHEVIEKLQSEL 1479
Cdd:TIGR02168  930 RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEA 970
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2203-2557 9.99e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 9.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2203 RRQVELLAYKVEQEKCIANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRyg 2282
Cdd:COG1196   224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE-- 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2283 hvtwsycgtssasAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNN 2362
Cdd:COG1196   302 -------------QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2363 QLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQ 2442
Cdd:COG1196   369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2443 ETQVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQErcVELRREKEVSGNLRSAVDALRTHKQELGC-CL 2521
Cdd:COG1196   449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL--LLLEAEADYEGFLEGVKAALLLAGLRGLAgAV 526

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 755534236 2522 QREREKAAWLQAELEQLSARVKEQEARKDARRMERR 2557
Cdd:COG1196   527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 142-529 2.79e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.99  E-value: 2.79e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   142 LQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLKQ 221
Cdd:pfam02463  634 LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELK 713

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   222 DWESERELCLENLRQELSLKHQSEMEGLQSQF-QKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAA--IKKLQEDLQS 298
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIdEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREktEKLKVEEEKE 793

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   299 EHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLwSQLESMKTNREELNgswdpvlaqashlEELEHLR 378
Cdd:pfam02463  794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEEL-ALELKEEQKLEKLA-------------EEELERL 859

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   379 SGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLESTEISSSCVLPEETSGREGKEPPD 458
Cdd:pfam02463  860 EEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755534236   459 PLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQ-------MKEEFQKKEAEWELSREELKREAEERLASMFLELREKAE 529
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEElgkvnlmAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 156-430 2.35e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.99  E-value: 2.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   156 MLNGRRAQELALLQSRQQcELELLREQhaREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLKQDWE---SERELCLE 232
Cdd:TIGR02168  660 VITGGSAKTNSSILERRR-EIEELEEK--IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSrqiSALRKDLA 736

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   233 NLRQ--ELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEA---QHQAAIKKLQEDLQSEHCQY--LQ 305
Cdd:TIGR02168  737 RLEAevEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAqieQLKEELKALREALDELRAELtlLN 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   306 DLEQKFREKEKAKELELETLQASYEDLKAQS---QEEIRLLWSQLESMKTNREELNGSWDPVLAQASHLEELEHLRSGFA 382
Cdd:TIGR02168  817 EEAANLRERLESLERRIAATERRLEDLEEQIeelSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL 896

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 755534236   383 QQQQQERAQHESELEHLRVYFEkKLKDAEKTYQEDLTVFQQRLQEARE 430
Cdd:TIGR02168  897 EELSEELRELESKRSELRRELE-ELREKLAQLELRLEGLEVRIDNLQE 943
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2344-2604 1.26e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.68  E-value: 1.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2344 SRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKE---LQIEASRCEALLAQEKGQLSELQKSLEAERSR----SLE 2416
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEEleqLRKELEELSRQISALRKDLARLEAEVEQLEERiaqlSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2417 LSEALQHERLLTEQLSRNSQEACARQETQVQhaLLRKLKAEKTRALELEAMLEKVQKQAAHTQqqleaqaqercVELRRE 2496
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAEIEE--LEAQIEQLKEELKALREALDELRAELTLLN-----------EEAANL 822

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2497 KEVSGNLRSAVDALRTHKQELGCCLQREREKAAWLQAELEQLSARVKEQEARKDARRMERRSSRADLDKRKWQRDK--ET 2574
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEElsEE 902

                          250       260       270
                   ....*....|....*....|....*....|
gi 755534236  2575 LRELEIQRQRDEHKIEQLQRLVRELRWKEE 2604
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLE 932
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 485-1371 2.75e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.44  E-value: 2.75e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   485 EEKIQQMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSL 564
Cdd:pfam02463  194 ELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   565 MEQQghLRQLEQELTRDDLLPCSQCGQEPAMAQEEKNGALLREKedcaLQLLMAQNRFLEERKEimekfaKEQDAFLRDA 644
Cdd:pfam02463  274 NKEE--EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEK----LKESEKEKKKAEKELK------KEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   645 QEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKRHLSNLDELES 724
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   725 CYVADVQTIRDEHQQALELLRAELEEQLQKKEschremLTQELENLKRQHAEElQSVRDSLRMEMSAQHIENGKGPAADL 804
Cdd:pfam02463  422 KEEKKEELEILEEEEESIELKQGKLTEEKEEL------EKQELKLLKDELELK-KSEDLLKETQLVKLQEQLELLLSRQK 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   805 QGAhqqqdpamALHNEGHLLVEDGDAVLRSVDAEGLLHQAGPQELGDAHTVemqksqAELAKPQELQASQDQVAQVRDKV 884
Cdd:pfam02463  495 LEE--------RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVA------VENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   885 FllnrELEECRAELEQLQQRRERENQEGTTLICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGL 964
Cdd:pfam02463  561 E----ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTK 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   965 LLDHEDAADTSDARLAAAALGDMWSDEGLLEIDRTLPEGAETSSVCEISSHVCESFFISPENTLDCEQPIRRVYQSLSTA 1044
Cdd:pfam02463  637 LKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1045 VEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALEL-HTAKGLLEGFKVEKV 1123
Cdd:pfam02463  717 LEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEReKTEKLKVEEEKEEKL 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1124 DLQEALGKKEESEQQLILEledlrkQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLtrvqwesrkqS 1203
Cdd:pfam02463  797 KAQEEELRALEEELKEEAE------LLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL----------E 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1204 EKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIqRLEGQ 1283
Cdd:pfam02463  861 EEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE-EEPEE 939

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1284 LRQAARPRPPGPRDSqcvQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEEL 1363
Cdd:pfam02463  940 LLLEEADEKEKEENN---KEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016


                   ....*...
gi 755534236  1364 EKQKKSME 1371
Cdd:pfam02463 1017 QRLKEFLE 1024
PTZ00121 PTZ00121
MAEBL; Provisional
 1054-1377 2.45e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 2.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1054 DSSKQLEEARQLHRCVEREFRHRNEEMAQAMQ-KQQELLERLREESAAKDRLALELHTAKgllEGFKVEKVDLQEALGKK 1132
Cdd:PTZ00121 1525 DEAKKAEEAKKADEAKKAEEKKKADELKKAEElKKAEEKKKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKLY 1601

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1133 EESEQqliLELEDLRKQLQQ--AARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSE-KDRAT 1209
Cdd:PTZ00121 1602 EEEKK---MKAEEAKKAEEAkiKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdKKKAE 1678

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1210 LLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQ---RQFMDDQAAEREHEREEFQQEIQRLEGQLRQ 1286
Cdd:PTZ00121 1679 EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeeNKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK 1758

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1287 AARPRPPGPRDSQCVQLDEEVeLLQEKLREKLDGFNELVIK--KDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELE 1364
Cdd:PTZ00121 1759 IAHLKKEEEKKAEEIRKEKEA-VIEEELDEEDEKRRMEVDKkiKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVAD 1837

                         330
                  ....*....|...
gi 755534236 1365 KQKKSMEELKEKE 1377
Cdd:PTZ00121 1838 SKNMQLEEADAFE 1850
PTZ00121 PTZ00121
MAEBL; Provisional
 2220-2605 3.46e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 3.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2220 ANELQKtlSKEQETASDVRK----RLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLR---LRYGHVTWSYCGTS 2292
Cdd:PTZ00121 1184 AEEVRK--AEELRKAEDARKaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKaeeERNNEEIRKFEEAR 1261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2293 SASAGRAVLDGKEKELKVVlEELE--SERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLcvALKH 2370
Cdd:PTZ00121 1262 MAHFARRQAAIKAEEARKA-DELKkaEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAA--KKKA 1338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2371 ERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSealQHERLLTEQLSRNSQEACARQETqvqhal 2450
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK---AEEKKKADEAKKKAEEDKKKADE------ 1409

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2451 LRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRthKQELGCCLQREREKAAW 2530
Cdd:PTZ00121 1410 LKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK--KADEAKKKAEEAKKADE 1487

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755534236 2531 LQAELEQlsARVKEQEARKDArrmERRSSRADLDKRKWQRDKETLRELEIQRQRDEHKIEQLQRLVRELRWKEEV 2605
Cdd:PTZ00121 1488 AKKKAEE--AKKKADEAKKAA---EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEEL 1557
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 203-532 5.67e-05

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 48.86  E-value: 5.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  203 EKLRSEMEKNAQT--------IETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKELSEQKvelekifqaKHEA 274
Cdd:NF033838   72 SEIQKSLDKRKHTqnvalnkkLSDIKTEYLYELNVLKEKSEAELTSKTKKELDAAFEQFKKDTLEPG---------KKVA 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  275 EVSLKNLEAQHQAAIKKlQEDLQSEHCQYLQDLEQKFREKE-KAKELELETLQAsyEDLKAQSQEEIRLLWSQLESMKtn 353
Cdd:NF033838  143 EATKKVEEAEKKAKDQK-EEDRRNYPTNTYKTLELEIAESDvEVKKAELELVKE--EAKEPRDEEKIKQAKAKVESKK-- 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  354 reelngswdpvlAQASHLEELEHLRsgfaqqqqqERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR--LQE-ARE 430
Cdd:NF033838  218 ------------AEATRLEKIKTDR---------EKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRgvLGEpATP 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  431 DSLESTEISSSCVLPEETsgregkePPDPlDLQLGQpKVQESlvedcQVKLSKAEEKIQQMKEEFQK------------- 497
Cdd:NF033838  277 DKKENDAKSSDSSVGEET-------LPSP-SLKPEK-KVAEA-----EKKVEEAKKKAKDQKEEDRRnyptntyktlele 342

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 755534236  498 --------KEAEWELSREELKR-EAEERLAsmflELREKAESEK 532
Cdd:NF033838  343 iaesdvkvKEAELELVKEEAKEpRNEEKIK----QAKAKVESKK 382
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1071-1382 1.07e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1071 REFRHRNEEMAQAMQKQQELLERLREesaakdrLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQL 1150
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIID-------LEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1151 QQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDqlvqhrg 1230
Cdd:pfam02463  239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD------- 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1231 caqLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLE--GQLRQAARPRPPGPRDSQC---VQLDE 1305
Cdd:pfam02463  312 ---DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEelEKLQEKLEQLEEELLAKKKlesERLSS 388

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755534236  1306 EVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQE 1382
Cdd:pfam02463  389 AAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2304-2606 1.13e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2304 KEKELKVVLEELESERgkgqALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVA-LKHERAAKDNLQKEL 2382
Cdd:pfam02463  171 KKEALKKLIEETENLA----ELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDyLKLNEERIDLLQELL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2383 QIEASRCEALLAQEKGQLSELQKSLEAERSRslELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRAL 2462
Cdd:pfam02463  247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEE--EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2463 ELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRTHKQELGCCLQREREKAAWLQAELEQLSARV 2542
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755534236  2543 KEQEARKDARRMERRSSRADLDKRKWQRDKETLRELEIQRQRDEHKIEQLQRLVRELRWKEEVS 2606
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELK 468
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 2797-2875 1.52e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 104.98  E-value: 1.52e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755534236  2797 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKitmSRPFTKFRTAVRVVIAVLRLRFLVKKW 2875
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS---RKPRRKLKSAALAVIAIARMKRLAREW 77
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1087-1662 2.08e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 2.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1087 QQELLERLREESAAKDRLA-LELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKS 1165
Cdd:COG1196   219 KEELKELEAELLLLKLRELeAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1166 VLWNQKETLTNEAKEREAALQEEVESLTRVQwESRKQSEKDRATLLSQMRVLESELEDQLvqhrgcAQLAEEVATLKQQL 1245
Cdd:COG1196   299 RLEQDIARLEERRRELEERLEELEEELAELE-EELEELEEELEELEEELEEAEEELEEAE------AELAEAEEALLEAE 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1246 AALDKHLRSQRQFmDDQAAEREHEREEFQQEIQRLEGQLRQAARprppgprdsQCVQLDEEVELLQEKLREKLDGFNELV 1325
Cdd:COG1196   372 AELAEAEEELEEL-AEELLEALRAAAELAAQLEELEEAEEALLE---------RLERLEEELEELEEALAELEEEEEEEE 441

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1326 IKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGD--LLLTTVSRSGLDEAGCP 1403
Cdd:COG1196   442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADyeGFLEGVKAALLLAGLRG 521

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1404 MLPQGSSSRGPEAQPDVTERALLqhENEVVHRRNSEIDELKSLIENLQEN-------------QRQLQKDKAEEIEQLHE 1470
Cdd:COG1196   522 LAGAVAVLIGVEAAYEAALEAAL--AAALQNIVVEDDEVAAAAIEYLKAAkagratflpldkiRARAALAAALARGAIGA 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1471 VIEKLQSELSLMGPKVHEVSDPQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVF--GQLLADQAHGHSQALEALQQ 1548
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSagGSLTGGSRRELLAALLEAEA 679

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1549 RLQDAEEVAARHLAELEHcVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLEIDAvnkwkvshsleleAILLALAHFR 1628
Cdd:COG1196   680 ELEELAERLAEEELELEE-ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE-------------ELLEELLEEE 745

                         570       580       590
                  ....*....|....*....|....*....|....
gi 755534236 1629 HALEQQTCATPDEPPELRQLRVQCARLSHQLQVL 1662
Cdd:COG1196   746 ELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1039-1610 6.47e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 6.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1039 QSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQEL-------LERLREESAAKDRLALELHTA 1111
Cdd:COG1196   249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLeqdiarlEERRRELEERLEELEEELAEL 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1112 KGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVES 1191
Cdd:COG1196   329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1192 LtrvqwesrKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQfmddqaaEREHERE 1271
Cdd:COG1196   409 E--------EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA-------ELLEEAA 473

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1272 EFQQEIQRLEGQLRQAArprppgPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNAS 1351
Cdd:COG1196   474 LLEAALAELLEELAEAA------ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA 547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1352 IQRQMVQLQEELEKQkksmeelkeKEILKQENMGdllltTVSRSGLDEAgcpmlpQGSSSRGPEAQPDVTERALLQHENE 1431
Cdd:COG1196   548 LQNIVVEDDEVAAAA---------IEYLKAAKAG-----RATFLPLDKI------RARAALAAALARGAIGAAVDLVASD 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1432 VVHRRNSEIDELKSLIENLQENQRQLQKDKAEEIEQLHEVIEKLQSELSLMGPkvhevsdpqagslhselaclRGEGLGG 1511
Cdd:COG1196   608 LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG--------------------SLTGGSR 667

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1512 QALRSELQAAQAAKEVFGQLLADQAHGHSQALEALQQRLQDAEEVAARHLAELEHCVALREAEVEAMASQIQEFAATLKA 1591
Cdd:COG1196   668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                         570
                  ....*....|....*....
gi 755534236 1592 KEAIIEQRDLEIDAVNKWK 1610
Cdd:COG1196   748 LEEEALEELPEPPDLEELE 766
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 868-1475 7.34e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 7.34e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  868 QELQASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRERENQEGTTLicmlRADLELAQGEGKALRDALRRLLDLFGDT 947
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA----QAEEYELLAELARLEQDIARLEERRREL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  948 LKAAVTLKSRISERAGLLLDHEDAADTSDARLAAAALGDMWSDEGLLEIDRTLPEgaetssvceisshvcesffispent 1027
Cdd:COG1196   315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE------------------------- 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1028 ldceqpIRRVYQSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALE 1107
Cdd:COG1196   370 ------AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1108 LHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQE 1187
Cdd:COG1196   444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1188 EVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATL------KQQLAALDKHLRSQRQFMDD 1261
Cdd:COG1196   524 GAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLpldkirARAALAAALARGAIGAAVDL 603

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1262 QAAEREHEREEFQQEIQRLEGQLRQAARPRPPGPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEE 1341
Cdd:COG1196   604 VASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE 683

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1342 IKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDLLLTTVSRSGLDEAgcpMLPQGSSSRGPEAQPDVT 1421
Cdd:COG1196   684 LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL---EEEELLEEEALEELPEPP 760

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755534236 1422 ERALLQHENEVVHRRNSE--------IDELKSLIENLQENQRQLQkDKAEEIEQLHEVIEKL 1475
Cdd:COG1196   761 DLEELERELERLEREIEAlgpvnllaIEEYEELEERYDFLSEQRE-DLEEARETLEEAIEEI 821
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 118-584 1.18e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 1.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  118 LELEALRLSLNNMHTAQLELTQA-NLQKEKETALTELREMLNGRRAQELALLQSRQQcELELLREQHAREKEEMAlrsgq 196
Cdd:COG1196   281 LELEEAQAEEYELLAELARLEQDiARLEERRRELEERLEELEEELAELEEELEELEE-ELEELEEELEEAEEELE----- 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  197 EAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQsemeglQSQFQKELSEQKVELEKIFQAKHEAEV 276
Cdd:COG1196   355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ------LEELEEAEEALLERLERLEEELEELEE 428

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  277 SLKNLEAQHQAAIKKLQEDLQSEhcQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLEsMKTNREE 356
Cdd:COG1196   429 ALAELEEEEEEEEEALEEAAEEE--AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE-AEADYEG 505

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  357 LNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLEST 436
Cdd:COG1196   506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR 585

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  437 EISSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAEER 516
Cdd:COG1196   586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755534236  517 LASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDLL 584
Cdd:COG1196   666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 859-1484 2.36e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.97  E-value: 2.36e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  859 KSQAELA-KPQELQASQDQVaqvrdKVFLLNRELEECRAELEQLQQRRERENQEgttlICMLRADLELAQGEGKALRDAL 937
Cdd:COG1196   206 ERQAEKAeRYRELKEELKEL-----EAELLLLKLRELEAELEELEAELEELEAE----LEELEAELAELEAELEELRLEL 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  938 RRLLDLFGDTLKAAVTLKSRISE-RAGLLLDHEDAADTSDARLAAAAlgdmwsdegllEIDRtlpegaetssvceisshv 1016
Cdd:COG1196   277 EELELELEEAQAEEYELLAELARlEQDIARLEERRRELEERLEELEE-----------ELAE------------------ 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1017 cesffispentldceqpIRRVYQSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLRE 1096
Cdd:COG1196   328 -----------------LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1097 ESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTN 1176
Cdd:COG1196   391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1177 EAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQR 1256
Cdd:COG1196   471 EAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQN 550

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1257 QFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRPPGPRDSQCVQLDEEVELLQEKLRE---KLDGFNELVIKKDFADQ 1333
Cdd:COG1196   551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREadaRYYVLGDTLLGRTLVAA 630

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1334 QLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDLLLTTVSRSGLDEAGCPMLPQGSSSRG 1413
Cdd:COG1196   631 RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA 710

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755534236 1414 PEAQPDVTERALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAEEIEQLHEVIEKLQSELSLMGP 1484
Cdd:COG1196   711 EAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 142-723 1.49e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.49e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  142 LQKEKETAL--TELREMLNGRRAQELALlqsrqqcELELLREQHAREKEEMalrsgQEAAELKEKLRSEMEKNAQTIETL 219
Cdd:COG1196   205 LERQAEKAEryRELKEELKELEAELLLL-------KLRELEAELEELEAEL-----EELEAELEELEAELAELEAELEEL 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  220 KQDweserelcLENLRQELSLKHQSEMEgLQSQFQKELSEQKVELEKIfQAKHEAEVSLKNLEAQHQAAIKKLQEDLQSe 299
Cdd:COG1196   273 RLE--------LEELELELEEAQAEEYE-LLAELARLEQDIARLEERR-RELEERLEELEEELAELEEELEELEEELEE- 341

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  300 hcqyLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESMKTNREELngswdpvLAQASHLEELEHLRS 379
Cdd:COG1196   342 ----LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA-------AELAAQLEELEEAEE 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  380 GfaqqQQQERAQHESELEHLrvyfEKKLKDAEKTYQEDLTVFQQRLQEAREDSLESTEISSScVLPEETSGREGKEPPDP 459
Cdd:COG1196   411 A----LLERLERLEEELEEL----EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL-LAELLEEAALLEAALAE 481

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  460 LDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKE-----AEWELSREELKREAEERLASMFLELREKAESEKLS 534
Cdd:COG1196   482 LLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAA 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  535 IIsrfehressmRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDLLPCSQCGQEPAMAQEEKNGALLREKEDCALQ 614
Cdd:COG1196   562 AI----------EYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAAR 631

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  615 LLMAQNRFLEERKEIMEKFAKEQDAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLE 694
Cdd:COG1196   632 LEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE 711

                         570       580
                  ....*....|....*....|....*....
gi 755534236  695 THVAELQVKHNAEISALEKRHLSNLDELE 723
Cdd:COG1196   712 AEEERLEEELEEEALEEQLEAEREELLEE 740
PTZ00121 PTZ00121
MAEBL; Provisional
 133-647 3.32e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 3.32e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  133 AQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEM-------------ALRSGQEAA 199
Cdd:PTZ00121 1263 AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAkkkaeeakkkadaAKKKAEEAK 1342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  200 ELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKELSEQKVELE----------KIFQ 269
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADelkkaaaakkKADE 1422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  270 AKHEAEVSLKNLEAQHQAAIKKLQEDLQ--SEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQL 347
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKKADEAKkkAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  348 ---ESMKTNREELNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR 424
Cdd:PTZ00121 1503 kkaAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK 1582

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  425 LQEAREdsLESTEISSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQV---------------KLSKAEEKIQ 489
Cdd:PTZ00121 1583 AEEAKK--AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVeqlkkkeaeekkkaeELKKAEEENK 1660

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  490 QMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISRFEHRESsmrhlqdQQAAQILDLERSLMEQQG 569
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK-------KKAEELKKAEEENKIKAE 1733

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755534236  570 HLRQLEQELTRDdllpcsqcGQEPAMAQEEKNGALLREKEDCAlqllmAQNRFLEERKEIMEKFAKEQDAFLRDAQEK 647
Cdd:PTZ00121 1734 EAKKEAEEDKKK--------AEEAKKDEEEKKKIAHLKKEEEK-----KAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1069-1387 4.11e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 4.11e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1069 VEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQlilELEDLRK 1148
Cdd:TIGR02169  668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE---RLEELEE 744

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1149 QLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQS----EKDRATLLSQMRVLESELEDQ 1224
Cdd:TIGR02169  745 DLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAElsklEEEVSRIEARLREIEQKLNRL 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1225 lvqHRGCAQLAEEVATLKQQLAALDkhlrSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAarprppgprDSQCVQLD 1304
Cdd:TIGR02169  825 ---TLEKEYLEKEIQELQEQRIDLK----EQIKSIEKEIENLNGKKEELEEELEELEAALRDL---------ESRLGDLK 888

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1305 EEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEkQKKSMEELKEKEILKQENM 1384
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPE-EELSLEDVQAELQRVEEEI 967


                   ...
gi 755534236  1385 GDL 1387
Cdd:TIGR02169  968 RAL 970
PTZ00121 PTZ00121
MAEBL; Provisional
 152-784 4.16e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.93  E-value: 4.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  152 ELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQEAAELK----EKLRSEMEKNAQTIETLKQDWESER 227
Cdd:PTZ00121 1186 EVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKkdaeEAKKAEEERNNEEIRKFEEARMAHF 1265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  228 ELCLENLRQELSLKHQsEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAIKKLQEDLQSEHCQYLQDL 307
Cdd:PTZ00121 1266 ARRQAAIKAEEARKAD-ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKA 1344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  308 EQKFREKEKAKELELETLQASYEDLKAQSQEEIRllwsQLESMKTNREELNGSWDPVLAQASHLEELEHLRSGFAQQQQQ 387
Cdd:PTZ00121 1345 AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK----KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA 1420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  388 ERAQHESelEHLRVYFEKKLKDAEKTYQEDLtvfQQRLQEAREDSLESTEISSSCVLPEETSGREGKEPPDPLDLQLGQP 467
Cdd:PTZ00121 1421 DEAKKKA--EEKKKADEAKKKAEEAKKADEA---KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA 1495

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  468 KVQESLVEDCQVKLSKAEE--KIQQMKEEFQKKEAEWELSREELKREAEERLASmflELREKAESEKLSIISRFEH--RE 543
Cdd:PTZ00121 1496 KKKADEAKKAAEAKKKADEakKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD---ELKKAEELKKAEEKKKAEEakKA 1572

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  544 SSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTrddllpcsqcGQEPAMAQEEKNGA-LLREKEDCALQLLMAQNRF 622
Cdd:PTZ00121 1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK----------AEEAKKAEEAKIKAeELKKAEEEKKKVEQLKKKE 1642

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  623 LEERKEIMEKFAKEQDAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAElQV 702
Cdd:PTZ00121 1643 AEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAE-EL 1721

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  703 KHNAEISALEKRHLSNLDELESCYVADVQTIRDEH---QQALELLRAELEEQLQKKESCHREMLTQELENLKRQHAEELQ 779
Cdd:PTZ00121 1722 KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKkkiAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801


                  ....*
gi 755534236  780 SVRDS 784
Cdd:PTZ00121 1802 DIFDN 1806
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 483-1157 4.17e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 4.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  483 KAEEKIQQMKEEFQK---KEAEWELSREELKREAE--ERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQI 557
Cdd:COG1196   176 EAERKLEATEENLERledILGELERQLEPLERQAEkaERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  558 LDLERSLMEQQGHLRQLEQELTRDDLlpcsqcgqepamaQEEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAKEQ 637
Cdd:COG1196   256 EELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  638 DAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKR-HL 716
Cdd:COG1196   323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAaQL 402

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  717 SNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQKKEScHREMLTQELENLKRQHAEELQSVRDSLRMEMSAQHIEN 796
Cdd:COG1196   403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  797 GKGPAADLQGAHQQQDPAMALHNEGhllvEDGDAVLRSVDAEGLLHQAGPQELGDAHTVEMQKSQAELAKPQELQASQDQ 876
Cdd:COG1196   482 LLEELAEAAARLLLLLEAEADYEGF----LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  877 VAQVRDKvFLLNRELEecRAELEQLQQRRERENQEgttlicmlRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKS 956
Cdd:COG1196   558 VAAAAIE-YLKAAKAG--RATFLPLDKIRARAALA--------AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT 626

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  957 RISERAGLLLDHEDAADTSDARLAAAALGdmwsdeglleidrtlpegaetssvceisshvcesffispentldceqpirr 1036
Cdd:COG1196   627 LVAARLEAALRRAVTLAGRLREVTLEGEG--------------------------------------------------- 655

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1037 VYQSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLE 1116
Cdd:COG1196   656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE 735

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|.
gi 755534236 1117 GFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAAREL 1157
Cdd:COG1196   736 ELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 634-1194 5.60e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 5.60e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  634 AKEQDAFLRdAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQAL---LETHVAELQvKHNAEISA 710
Cdd:COG1196   222 LKELEAELL-LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELeleLEEAQAEEY-ELLAELAR 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  711 LEKRHLSNLDELEScyvADVQTIRDEHQQALELLRAELEEQLQKKESCHREMLTQELENLKRQHAEELQSVRDSLRMEMS 790
Cdd:COG1196   300 LEQDIARLEERRRE---LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  791 AQHIENgkgpAADLQGAHQQQDPAMALHNEGHLLVEDGDAVLRSVDAEGLLHQAGpQELGDAHTVEMQKSQAELAKPQEL 870
Cdd:COG1196   377 AEEELE----ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE-EALAELEEEEEEEEEALEEAAEEE 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  871 QASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRERENQEGTTLICMLRADLELAQGEGKA-LRDALRRLLDLFGDTLK 949
Cdd:COG1196   452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAlLLAGLRGLAGAVAVLIG 531

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  950 AAVTLKSRISERAGLLLDHEDAADTSDARLAAAALGDmwSDEGLLEIDRTLPEGAETSSVCEISSHVCESFFISPENTLD 1029
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA--AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1030 CEQPIRRVYQSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELH 1109
Cdd:COG1196   610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1110 TAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEV 1189
Cdd:COG1196   690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769


                  ....*
gi 755534236 1190 ESLTR 1194
Cdd:COG1196   770 ERLER 774
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 118-631 1.17e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 1.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  118 LELEALRLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQE 197
Cdd:COG1196   227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  198 AAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQ-SEMEGLQSQFQKELSEQKVELEKIFQAKHEAEV 276
Cdd:COG1196   307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEElEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  277 SLKNLEAQHQAAIKKLQEDLQSEHcQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESMKTNREE 356
Cdd:COG1196   387 ELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  357 LNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQE--DLTVFQQRLQEAREDSL- 433
Cdd:COG1196   466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvaVLIGVEAAYEAALEAALa 545

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  434 --------ESTEISSSCV--LPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWE 503
Cdd:COG1196   546 aalqnivvEDDEVAAAAIeyLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR 625

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  504 LSREELKREAEERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDL 583
Cdd:COG1196   626 TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE 705

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 755534236  584 lpcsqcgQEPAMAQEEKNGALLREKEDCALQLLMAQNRFLEERKEIME 631
Cdd:COG1196   706 -------ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 669-1479 1.34e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 1.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   669 ELETKHRSELTEQLASSESRRQALLEThVAELQVKHNAEISALEKRHlsnldelescyvADVQTIRDEHQQALELLRAEL 748
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEE-LKEAEEELEELTAELQELE------------EKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   749 EEQLQKKEschremLTQELENLKRQHAEELQSVRDSLRmEMSAQHIENGKGPAADLQGAHQQQDPAMALHNEghllvedg 828
Cdd:TIGR02168  288 KELYALAN------EISRLEQQKQILRERLANLERQLE-ELEAQLEELESKLDELAEELAELEEKLEELKEE-------- 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   829 davlrsvdaegllHQAGPQELGDAHTVEMQKSQAELAKPQELQASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRERE 908
Cdd:TIGR02168  353 -------------LESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   909 NQEGTTLIC-MLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGLLLDHEDAADTSDARLAAAalgdm 987
Cdd:TIGR02168  420 QQEIEELLKkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL----- 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   988 wsdEGLLEIDRTLPEG--AETSSVCEISSHV-CESFFISPENTLDceqpirrvyQSLSTAVEGLLEMALDSSKQ------ 1058
Cdd:TIGR02168  495 ---ERLQENLEGFSEGvkALLKNQSGLSGILgVLSELISVDEGYE---------AAIEAALGGRLQAVVVENLNaakkai 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1059 --LEEARQ-------LHRCVEREFRHRNEEMAQAMQKQQELLERLrEESAAKDRLALElhtakGLLEGFKVEKvDLQEAL 1129
Cdd:TIGR02168  563 afLKQNELgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDL-VKFDPKLRKALS-----YLLGGVLVVD-DLDNAL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1130 G-KKEESEQQLILELED--------LRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEeveslTRVQWESR 1200
Cdd:TIGR02168  636 ElAKKLRPGYRIVTLDGdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE-----LRKELEEL 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1201 KQSEKDRATLLSQMRVLESELEDQLVQHRG-CAQLAEEVATLKQQLAALDKhlrsQRQFMDDQAAEREHEREEFQQEIQR 1279
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALRKDLARLEAeVEQLEERIAQLSKELTELEA----EIEELEERLEEAEEELAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1280 LEGQLRQAARprppgprdsQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQL 1359
Cdd:TIGR02168  787 LEAQIEQLKE---------ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1360 QEELEKQKKSMEELKEK-EILKQENMGDLLLTTVSRSGLDEAgcpmlpqgSSSRGPEAQPDVTERALLQHENEVVHRRNS 1438
Cdd:TIGR02168  858 AAEIEELEELIEELESElEALLNERASLEEALALLRSELEEL--------SEELRELESKRSELRRELEELREKLAQLEL 929

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 755534236  1439 EIDELKSLIENLQENQRQLQKDKAEEIEQLHEVIEKLQSEL 1479
Cdd:TIGR02168  930 RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEA 970
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1057-1697 1.83e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.92  E-value: 1.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1057 KQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESE 1136
Cdd:TIGR02168  288 KELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1137 QQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNE---AKEREAALQEEVESLTRVQWESRKQ--------SEK 1205
Cdd:TIGR02168  368 EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARlerLEDRRERLQQEIEELLKKLEEAELKelqaeleeLEE 447

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1206 DRATLLSQMRVLESELEDQLVQHRgcaQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQR--LEGQ 1283
Cdd:TIGR02168  448 ELEELQEELERLEEALEELREELE---EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgILGV 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1284 LRQAARPRP----------PGPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQ 1353
Cdd:TIGR02168  525 LSELISVDEgyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA 604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1354 RQMVQLQEELEKQKKSM-------EELKEK-EILKQENMGDLLLT----TVSRSG-------------------LDEAGC 1402
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLlggvlvvDDLDNAlELAKKLRPGYRIVTldgdLVRPGGvitggsaktnssilerrreIEELEE 684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1403 PMLPQGSSSRGPEAQPDVTERALLQHENEV-------------VHRRNSEIDELKSLIENLQENQRQLQK---DKAEEIE 1466
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELeqlrkeleelsrqISALRKDLARLEAEVEQLEERIAQLSKeltELEAEIE 764

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1467 QLHEVIEKLQSELSLMGPKVHEVSDPQAG-------------SLHSELACLRGEGLGGQALRSELQAAQAAKEVFGQLLA 1533
Cdd:TIGR02168  765 ELEERLEEAEEELAEAEAEIEELEAQIEQlkeelkalrealdELRAELTLLNEEAANLRERLESLERRIAATERRLEDLE 844

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1534 DQAHGHSQALEALQQRLQDAEEVAARHLAELEHCVALREAEVEAMA---SQIQEFAATLKAKEAIIEQRDLEIDAVNKWK 1610
Cdd:TIGR02168  845 EQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAllrSELEELSEELRELESKRSELRRELEELREKL 924

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1611 VSHSLELEAILLALAHFRHALEQQTCATPDEPPELRQLRVQCARlshqlqvlyrpflKCRMQLDQHQPHVASIGCANPCA 1690
Cdd:TIGR02168  925 AQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE-------------EARRRLKRLENKIKELGPVNLAA 991


                   ....*..
gi 755534236  1691 DDELEQE 1697
Cdd:TIGR02168  992 IEEYEEL 998
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1038-1599 8.01e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 8.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1038 YQSLSTAVEGL-LEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRlalELHTAKGLLE 1116
Cdd:TIGR02168  215 YKELKAELRELeLALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE---EIEELQKELY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1117 GFKVEKVDLQEALGKKEESEQQLI-------LELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEV 1189
Cdd:TIGR02168  292 ALANEISRLEQQKQILRERLANLErqleeleAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1190 ESLT--RVQWESRK----QSEKDRATLLSQMRVLESELEDQLVQHrgcAQLAEEVATLKQQLAALDKH-LRSQRQFMDDQ 1262
Cdd:TIGR02168  372 SRLEelEEQLETLRskvaQLELQIASLNNEIERLEARLERLEDRR---ERLQQEIEELLKKLEEAELKeLQAELEELEEE 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1263 AAEREHEREEFQQEIQRLEGQLRQAARPRPPGPRDSQcvQLDEEVELLqEKLREKLDGFNELVI-----KKDFAD----- 1332
Cdd:TIGR02168  449 LEELQEELERLEEALEELREELEEAEQALDAAERELA--QLQARLDSL-ERLQENLEGFSEGVKallknQSGLSGilgvl 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1333 QQLLIQEEEIKRLEETNASIQRQMVqLQEELEKQKKSMEELKEKEILKqenMGDLLLTTVSRSGLDEAGCPMLPQGSSSR 1412
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQNELGR---VTFLPLDSIKGTEIQGNDREILKNIEGFL 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1413 G---------PEAQPDVT-----------------ERALLQHEN-------EVVHR-----------------RNSEIDE 1442
Cdd:TIGR02168  602 GvakdlvkfdPKLRKALSyllggvlvvddldnaleLAKKLRPGYrivtldgDLVRPggvitggsaktnssileRRREIEE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1443 LKSLIENLQENQRQLQK---DKAEEIEQLHEVIEKLQSELSLMGPKVHEvsdpqagsLHSELACLRGEGLGGQALRSELQ 1519
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKalaELRKELEELEEELEQLRKELEELSRQISA--------LRKDLARLEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1520 AAQAAKEVFGQLLADQAHGHSQALEALQQRLQDAEEVAARHLAELEhcvALREA--EVEAMASQIQEFAATLKAKEAIIE 1597
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK---ALREAldELRAELTLLNEEAANLRERLESLE 830


                   ..
gi 755534236  1598 QR 1599
Cdd:TIGR02168  831 RR 832
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2203-2557 9.99e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 9.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2203 RRQVELLAYKVEQEKCIANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRyg 2282
Cdd:COG1196   224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE-- 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2283 hvtwsycgtssasAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNN 2362
Cdd:COG1196   302 -------------QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2363 QLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQ 2442
Cdd:COG1196   369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2443 ETQVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQErcVELRREKEVSGNLRSAVDALRTHKQELGC-CL 2521
Cdd:COG1196   449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL--LLLEAEADYEGFLEGVKAALLLAGLRGLAgAV 526

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 755534236 2522 QREREKAAWLQAELEQLSARVKEQEARKDARRMERR 2557
Cdd:COG1196   527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 345-1164 1.04e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.23  E-value: 1.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   345 SQLESMKTN-------REELNGSWDPVLAQASHLE-------ELEHLRSGFAQQQQQERAQHESELEHLrvyfEKKLKDA 410
Cdd:TIGR02168  179 RKLERTRENldrlediLNELERQLKSLERQAEKAErykelkaELRELELALLVLRLEELREELEELQEE----LKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   411 EKTYQEDLTVFQQRLQEARedsLESTEISSSCVLPEETSGREGKEPPDpLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQ 490
Cdd:TIGR02168  255 LEELTAELQELEEKLEELR---LEVSELEEEIEELQKELYALANEISR-LEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   491 MKEEFQKKEAEWELSREELKREAEErLASMFLELREKAESEKLSIISRFEHREssmrhlqdQQAAQILDLERSLMEQQGH 570
Cdd:TIGR02168  331 KLDELAEELAELEEKLEELKEELES-LEAELEELEAELEELESRLEELEEQLE--------TLRSKVAQLELQIASLNNE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   571 LRQLEQELTRddllpcsqcgqepamaQEEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAKEQDAFLRDAQEKhnh 650
Cdd:TIGR02168  402 IERLEARLER----------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEA--- 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   651 elQLLQQGHQQQLLALRMELETKHRsELTEQLASSESRRQALLETHVAELQVKHNAEISALEKRHLSNLDELESCYVADV 730
Cdd:TIGR02168  463 --LEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   731 QTIRDEHQQA---LELLRAELEEQLQKKESCHREMLTQelenLKRQHAEELQSVRDSLRMEmsaqhIENGKGPAADLQGA 807
Cdd:TIGR02168  540 EAALGGRLQAvvvENLNAAKKAIAFLKQNELGRVTFLP----LDSIKGTEIQGNDREILKN-----IEGFLGVAKDLVKF 610

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   808 HQQQDPAMALHNEGHLLVEDGDavlrsvDAEGLLHQAGPQELG---DAHTV---------EMQKSQAELAKPQELQASQD 875
Cdd:TIGR02168  611 DPKLRKALSYLLGGVLVVDDLD------NALELAKKLRPGYRIvtlDGDLVrpggvitggSAKTNSSILERRREIEELEE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   876 QVAQVRDKVFLLNRELEECRAELEQLQQRRE---RENQEGTTLICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAV 952
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELEqlrKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIE 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   953 TLKSRISERAGLLLDHEDAADTSDARLAAAAlgdmwsdEGLLEIDRTLPEGAETSSVCEISSHVCESFFISPENTL-DCE 1031
Cdd:TIGR02168  765 ELEERLEEAEEELAEAEAEIEELEAQIEQLK-------EELKALREALDELRAELTLLNEEAANLRERLESLERRIaATE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1032 QPIRRVYQSLSTAVEGLLEMAL----------DSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAK 1101
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAeieeleelieELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755534236  1102 DRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEK 1164
Cdd:TIGR02168  918 EELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 142-529 2.79e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.99  E-value: 2.79e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   142 LQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLKQ 221
Cdd:pfam02463  634 LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELK 713

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   222 DWESERELCLENLRQELSLKHQSEMEGLQSQF-QKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAA--IKKLQEDLQS 298
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIdEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREktEKLKVEEEKE 793

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   299 EHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLwSQLESMKTNREELNgswdpvlaqashlEELEHLR 378
Cdd:pfam02463  794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEEL-ALELKEEQKLEKLA-------------EEELERL 859

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   379 SGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLESTEISSSCVLPEETSGREGKEPPD 458
Cdd:pfam02463  860 EEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755534236   459 PLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQ-------MKEEFQKKEAEWELSREELKREAEERLASMFLELREKAE 529
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEElgkvnlmAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 859-1592 3.42e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 3.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   859 KSQAELAkpQELQASQDQVAQVrdKVFLLNRELEECRAELEQLQQRRERENQEGTTLicmlRADLELAQGEGKALRDALR 938
Cdd:TIGR02168  206 ERQAEKA--ERYKELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEEL----TAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   939 RLLDLFGD---TLKAAVTLKSRISERAGLLLDHEDAADTSDARLAAA-ALGDMWSDEGLLEIDRTLPEGAETSSVCEISS 1014
Cdd:TIGR02168  278 ELEEEIEElqkELYALANEISRLEQQKQILRERLANLERQLEELEAQlEELESKLDELAEELAELEEKLEELKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1015 HVCESFFISPENTLDCEQPIRRVYQSLSTAVEGLLEMALDSSKQLEEAR-QLHRCVEREFRHRNEEMAQAMQKQ----QE 1089
Cdd:TIGR02168  358 AELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEaRLERLEDRRERLQQEIEELLKKLEeaelKE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1090 LLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQL---ILELEDLRKQLQQAARELLTLKEEKS- 1165
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLqarLDSLERLQENLEGFSEGVKALLKNQSg 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1166 ------VLWNQKETLTNEAKEREAALQEEVESLT-------RVQWESRKQSEKDRATLL----SQMRVLESELEDQLVQH 1228
Cdd:TIGR02168  518 lsgilgVLSELISVDEGYEAAIEAALGGRLQAVVvenlnaaKKAIAFLKQNELGRVTFLpldsIKGTEIQGNDREILKNI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1229 RGCAQLAEE---------------------VATLKQQLAALDKHLRSQRQFMDD-------------------QAAEREH 1268
Cdd:TIGR02168  598 EGFLGVAKDlvkfdpklrkalsyllggvlvVDDLDNALELAKKLRPGYRIVTLDgdlvrpggvitggsaktnsSILERRR 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1269 EREEFQQEIQRLEGQLRQAarprppgprDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEET 1348
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAEL---------EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1349 NASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDL--------LLTTVSRSGLDEAgcpmlpqgsssrgpEAQPDV 1420
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELeaqieqlkEELKALREALDEL--------------RAELTL 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1421 TERALLQHENEVVHRRNsEIDELKSLIENLQENQRQLQKDKAE---EIEQLHEVIEKLQSELSLMGpKVHEVSDPQAGSL 1497
Cdd:TIGR02168  815 LNEEAANLRERLESLER-RIAATERRLEDLEEQIEELSEDIESlaaEIEELEELIEELESELEALL-NERASLEEALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1498 HSELACLRGEglgGQALRSELQAAQAAKevfgQLLADQAHGHSQALEALQQRLQD-AEEVAARHLAELEHCVALrEAEVE 1576
Cdd:TIGR02168  893 RSELEELSEE---LRELESKRSELRREL----EELREKLAQLELRLEGLEVRIDNlQERLSEEYSLTLEEAEAL-ENKIE 964

                          810
                   ....*....|....*.
gi 755534236  1577 AMASQIQEFAATLKAK 1592
Cdd:TIGR02168  965 DDEEEARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1085-1480 7.91e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 7.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1085 QKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLIL-ELEDLRKQLQQAARELLTLKEE 1163
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLkEKEALERQKEAIERQLASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1164 KsvlwnqkETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEdqlvqhrgcaQLAEEVATLKQ 1243
Cdd:TIGR02169  253 L-------EKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA----------SLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1244 QLaaldkhlrsqrQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRppgprdsqcVQLDEEVELLQEKLREKldgfne 1323
Cdd:TIGR02169  316 EL-----------EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRR---------DKLTEEYAELKEELEDL------ 369

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1324 lvikkdfadqqlliqEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQEnmgdlllttvsrsgldeagcp 1403
Cdd:TIGR02169  370 ---------------RAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQE--------------------- 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1404 mLPQGSSSRGPEAQPDVTerALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQK------DKAEEIEQLHEVIEKLQS 1477
Cdd:TIGR02169  414 -ELQRLSEELADLNAAIA--GIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKyeqelyDLKEEYDRVEKELSKLQR 490


                   ...
gi 755534236  1478 ELS 1480
Cdd:TIGR02169  491 ELA 493
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2073-2599 1.05e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 1.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2073 QALSEVTTDKGEKESLETHLTWSEELLRAIQEVFAREQEKAELQprpygsnLGDYNSLVQRLEKVIQEQgDPQKVQDHLC 2152
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA-------QAEEYELLAELARLEQDI-ARLEERRREL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2153 LSDRSSLLAEIQALRAQLRMTHLQNQEKLQQLCAALTSTEARGSQREHQLRRQVELLAYKVEQEKcIANELQKTLSKEQE 2232
Cdd:COG1196   315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE-ELEELAEELLEALR 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2233 TASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRyghvtwsycgtsSASAGRAVLDGKEKELKVVL 2312
Cdd:COG1196   394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE------------EALEEAAEEEAELEEEEEAL 461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2313 EELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLE-------KQLAQNNQLCVALKHERAAKDNLQKELQIE 2385
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvkAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2386 ASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRALELE 2465
Cdd:COG1196   542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2466 AMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRTHKQELGCCLQREREKAAWLQAELEQLSARVKEQ 2545
Cdd:COG1196   622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755534236 2546 EARKDARRMERRSSRADLDKRKWQRDKETLRELEIQRQRD------------------------EHKIEQLQRLVREL 2599
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELleeeelleeealeelpeppdleelERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 674-1281 1.28e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 1.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  674 HRSELTEQLASSESRRQALlETHVAELQvkhnAEISALEKRHLSNLDELEScyvadvQTIRDEHQQALELLRAELEEQLQ 753
Cdd:COG1196   233 KLRELEAELEELEAELEEL-EAELEELE----AELAELEAELEELRLELEE------LELELEEAQAEEYELLAELARLE 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  754 KKESCHREMLTQELENLKRQHAEELQSVRDSLRMEMSAQHIEngkgpAADLQGAHQQQDPAMALHNEGHLLVEDGDAVLR 833
Cdd:COG1196   302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELE-----EELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  834 SVDAEgllhqagpQELGDAHTVEMQKSQAELAKPQELQASQDQVAQVRDKvflLNRELEECRAELEQLQQRRERENQEGT 913
Cdd:COG1196   377 AEEEL--------EELAEELLEALRAAAELAAQLEELEEAEEALLERLER---LEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  914 TLICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGLLLDHEDAADTSDARLAAAALGDMWSDEGL 993
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA 525

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  994 LEIDRTLPEGAETSSVCEISSHVCEsffISPENTLDCEQPIRRVYQSLSTAVEGLLEMALDSSKQLEEARQLHRcVEREF 1073
Cdd:COG1196   526 VAVLIGVEAAYEAALEAALAAALQN---IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA-IGAAV 601

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1074 RHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQA 1153
Cdd:COG1196   602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL 681

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1154 ARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQwESRKQSEKDRATLLSQMRVLESELEDQLVQHrgcAQ 1233
Cdd:COG1196   682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE-ALEEQLEAEREELLEELLEEEELLEEEALEE---LP 757

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 755534236 1234 LAEEVATLKQQLAALdkhlrsqrqfmddqaaerehereefQQEIQRLE 1281
Cdd:COG1196   758 EPPDLEELERELERL-------------------------EREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1131-1554 2.02e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.99  E-value: 2.02e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1131 KKEESEQQLILELEDLrKQLQQAARELltlkeEKsvlwnQKETLTNEAK--EREAALQEEVESLTRVQWESRKQSEKDRa 1208
Cdd:TIGR02168  173 RRKETERKLERTRENL-DRLEDILNEL-----ER-----QLKSLERQAEkaERYKELKAELRELELALLVLRLEELREE- 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1209 tlLSQMRVLESELEDQlvqhrgCAQLAEEVATLKQQLAALdkhlRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAA 1288
Cdd:TIGR02168  241 --LEELQEELKEAEEE------LEELTAELQELEEKLEEL----RLEVSELEEEIEELQKELYALANEISRLEQQKQILR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1289 RprppgpRDSQCVQLDEEVELLQEKLREKLDgfnelvikkdfadqqllIQEEEIKRLEETNASIQRQMVQLQEELEKQKK 1368
Cdd:TIGR02168  309 E------RLANLERQLEELEAQLEELESKLD-----------------ELAEELAELEEKLEELKEELESLEAELEELEA 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1369 SMEELKEKEILKQENMGDLllttvsrsgldeagcpmlpqgsssrgpeaqpdvtERALLQHENEvVHRRNSEIDELKSLIE 1448
Cdd:TIGR02168  366 ELEELESRLEELEEQLETL----------------------------------RSKVAQLELQ-IASLNNEIERLEARLE 410

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1449 NLQENQRQLQKDKAEEIEQLHEVIEKLQSElslmgpkvhevsdpQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVF 1528
Cdd:TIGR02168  411 RLEDRRERLQQEIEELLKKLEEAELKELQA--------------ELEELEEELEELQEELERLEEALEELREELEEAEQA 476

                          410       420
                   ....*....|....*....|....*.
gi 755534236  1529 GQLLADQAHGHSQALEALQQRLQDAE 1554
Cdd:TIGR02168  477 LDAAERELAQLQARLDSLERLQENLE 502
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 156-430 2.35e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.99  E-value: 2.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   156 MLNGRRAQELALLQSRQQcELELLREQhaREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLKQDWE---SERELCLE 232
Cdd:TIGR02168  660 VITGGSAKTNSSILERRR-EIEELEEK--IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSrqiSALRKDLA 736

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   233 NLRQ--ELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEA---QHQAAIKKLQEDLQSEHCQY--LQ 305
Cdd:TIGR02168  737 RLEAevEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAqieQLKEELKALREALDELRAELtlLN 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   306 DLEQKFREKEKAKELELETLQASYEDLKAQS---QEEIRLLWSQLESMKTNREELNGSWDPVLAQASHLEELEHLRSGFA 382
Cdd:TIGR02168  817 EEAANLRERLESLERRIAATERRLEDLEEQIeelSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL 896

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 755534236   383 QQQQQERAQHESELEHLRVYFEkKLKDAEKTYQEDLTVFQQRLQEARE 430
Cdd:TIGR02168  897 EELSEELRELESKRSELRRELE-ELREKLAQLELRLEGLEVRIDNLQE 943
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1310-1602 3.55e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 3.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1310 LQEKLREKLdgFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMgDLLL 1389
Cdd:COG1196   218 LKEELKELE--AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE-YELL 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1390 TTVSRSGLDEAgcpmlpqgsssrgpeaqpdvTERALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAEEIEQLH 1469
Cdd:COG1196   295 AELARLEQDIA--------------------RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1470 EVIEKLQSelslmgpkvhevsdpQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVFGQLLADQAHGHSQALEALQQR 1549
Cdd:COG1196   355 EAEAELAE---------------AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 755534236 1550 LQDAEEVAARHLAELEHCVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLE 1602
Cdd:COG1196   420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2344-2604 1.26e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.68  E-value: 1.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2344 SRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKE---LQIEASRCEALLAQEKGQLSELQKSLEAERSR----SLE 2416
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEEleqLRKELEELSRQISALRKDLARLEAEVEQLEERiaqlSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2417 LSEALQHERLLTEQLSRNSQEACARQETQVQhaLLRKLKAEKTRALELEAMLEKVQKQAAHTQqqleaqaqercVELRRE 2496
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAEIEE--LEAQIEQLKEELKALREALDELRAELTLLN-----------EEAANL 822

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2497 KEVSGNLRSAVDALRTHKQELGCCLQREREKAAWLQAELEQLSARVKEQEARKDARRMERRSSRADLDKRKWQRDK--ET 2574
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEElsEE 902

                          250       260       270
                   ....*....|....*....|....*....|
gi 755534236  2575 LRELEIQRQRDEHKIEQLQRLVRELRWKEE 2604
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLE 932
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1049-1372 1.35e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.30  E-value: 1.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1049 LEMALDSSKQLEEARQLHRCVEREFRHR----NEEMAQAmQKQQELLERLREesAAKDRLALELHTAKGLLEGFKVEKVD 1124
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQlerlRREREKA-ERYQALLKEKRE--YEGYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1125 LQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQK-ETLTNEAKEREAALQEEVESLTRVQwESRKQS 1203
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEKERELEDAE-ERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1204 EKDRATLLSQMRVLESELEDQLVQHRGC----AQLAEEVATLKQQLAALDKHLRSQRQFMDD----------QAAEREHE 1269
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLteeyAELKEELEDLRAELEEVDKEFAETRDELKDyrekleklkrEINELKRE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1270 REEFQQEIQRLEGQLRQAaRPRPPGPRDSQcVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETN 1349
Cdd:TIGR02169  408 LDRLQEELQRLSEELADL-NAAIAGIEAKI-NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKEL 485

                          330       340
                   ....*....|....*....|...
gi 755534236  1350 ASIQRQMvqlqEELEKQKKSMEE 1372
Cdd:TIGR02169  486 SKLQREL----AEAEAQARASEE 504
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1075-1283 1.48e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.15  E-value: 1.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1075 HRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKvdLQEALGKKEESEQQLILELEDLRKQLQQAA 1154
Cdd:COG4913   238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWF--AQRRLELLEAELEELRAELARLEAELERLE 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1155 RELLTLKEEKSVLwnqKETLTNEAKEREAALQEEVESLTRvqweSRKQSEKDRATLLSQMRVLESEL---EDQLVQHRgc 1231
Cdd:COG4913   316 ARLDALREELDEL---EAQIRGNGGDRLEQLEREIERLER----ELEERERRRARLEALLAALGLPLpasAEEFAALR-- 386

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 755534236 1232 AQLAEEVATLKQQLAALDKHLRSQRqfmdDQAAEREHEREEFQQEIQRLEGQ 1283
Cdd:COG4913   387 AEAAALLEALEEELEALEEALAEAE----AALRDLRRELRELEAEIASLERR 434
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 485-1371 2.75e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.44  E-value: 2.75e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   485 EEKIQQMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERSL 564
Cdd:pfam02463  194 ELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   565 MEQQghLRQLEQELTRDDLLPCSQCGQEPAMAQEEKNGALLREKedcaLQLLMAQNRFLEERKEimekfaKEQDAFLRDA 644
Cdd:pfam02463  274 NKEE--EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEK----LKESEKEKKKAEKELK------KEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   645 QEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKRHLSNLDELES 724
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   725 CYVADVQTIRDEHQQALELLRAELEEQLQKKEschremLTQELENLKRQHAEElQSVRDSLRMEMSAQHIENGKGPAADL 804
Cdd:pfam02463  422 KEEKKEELEILEEEEESIELKQGKLTEEKEEL------EKQELKLLKDELELK-KSEDLLKETQLVKLQEQLELLLSRQK 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   805 QGAhqqqdpamALHNEGHLLVEDGDAVLRSVDAEGLLHQAGPQELGDAHTVemqksqAELAKPQELQASQDQVAQVRDKV 884
Cdd:pfam02463  495 LEE--------RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVA------VENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   885 FllnrELEECRAELEQLQQRRERENQEGTTLICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGL 964
Cdd:pfam02463  561 E----ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTK 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   965 LLDHEDAADTSDARLAAAALGDMWSDEGLLEIDRTLPEGAETSSVCEISSHVCESFFISPENTLDCEQPIRRVYQSLSTA 1044
Cdd:pfam02463  637 LKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1045 VEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALEL-HTAKGLLEGFKVEKV 1123
Cdd:pfam02463  717 LEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEReKTEKLKVEEEKEEKL 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1124 DLQEALGKKEESEQQLILEledlrkQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLtrvqwesrkqS 1203
Cdd:pfam02463  797 KAQEEELRALEEELKEEAE------LLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL----------E 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1204 EKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIqRLEGQ 1283
Cdd:pfam02463  861 EEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE-EEPEE 939

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1284 LRQAARPRPPGPRDSqcvQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEEL 1363
Cdd:pfam02463  940 LLLEEADEKEKEENN---KEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016


                   ....*...
gi 755534236  1364 EKQKKSME 1371
Cdd:pfam02463 1017 QRLKEFLE 1024
PTZ00121 PTZ00121
MAEBL; Provisional
 242-915 3.06e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 3.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  242 HQSEMEGLQ---SQFQKELSEQKVELEKIFQAKHEAEVSLKNL------EAQHQAAIKKLQEDLQSEHCQYLQDLeQKFR 312
Cdd:PTZ00121 1065 HVGQDEGLKpsyKDFDFDAKEDNRADEATEEAFGKAEEAKKTEtgkaeeARKAEEAKKKAEDARKAEEARKAEDA-RKAE 1143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  313 EKEKAKELELETLQASYEDlkAQSQEEIRLLWSQLESMKTNREElngswdpVLAQASHLEELEHLRsgfaQQQQQERAQH 392
Cdd:PTZ00121 1144 EARKAEDAKRVEIARKAED--ARKAEEARKAEDAKKAEAARKAE-------EVRKAEELRKAEDAR----KAEAARKAEE 1210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  393 ESELEHLRVYFEKKLKDAEKtyqedltvfqqRLQEAREDSLEST---EISSSCVLPEETSGREGKEPPDPLDLQLGQPKV 469
Cdd:PTZ00121 1211 ERKAEEARKAEDAKKAEAVK-----------KAEEAKKDAEEAKkaeEERNNEEIRKFEEARMAHFARRQAAIKAEEARK 1279

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  470 QESLVEDCQVK----LSKAEEKiqqMKEEFQKKEAEWELSREELKREAEERLASMfLELREKAESEKLSIISRFEHRESS 545
Cdd:PTZ00121 1280 ADELKKAEEKKkadeAKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKKA-DAAKKKAEEAKKAAEAAKAEAEAA 1355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  546 MRHLQ-DQQAAQILDLERSLMEQQGH-LRQLEQELTRDDLLPcSQCGQEPAMAQEEKNGALLREKEDcALQLLMAQNRFL 623
Cdd:PTZ00121 1356 ADEAEaAEEKAEAAEKKKEEAKKKADaAKKKAEEKKKADEAK-KKAEEDKKKADELKKAAAAKKKAD-EAKKKAEEKKKA 1433

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  624 EERKEIMEKfAKEQDAFLRDAQEKHNHELQLLQQGHQQQLLALRMELETKHRSELTEQLASsESRRQALLETHVAELQVK 703
Cdd:PTZ00121 1434 DEAKKKAEE-AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE-EAKKKADEAKKAAEAKKK 1511

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  704 HNAEISALEKRHLSNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQKKESCHREMLTQELENLKRQHAEELQSVRD 783
Cdd:PTZ00121 1512 ADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE 1591

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  784 SLRMEMSAQHIENGKGPAADLQGAHQQQDPAMALHNEGHLLVEDGDAVLRSVDAEGLLHQAGPQELGDAHTVEMQKSQAE 863
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE 1671

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|..
gi 755534236  864 LAKPQELQASQDQVAQvRDKVFLLNRELEECRaELEQLQQRRERENQEGTTL 915
Cdd:PTZ00121 1672 EDKKKAEEAKKAEEDE-KKAAEALKKEAEEAK-KAEELKKKEAEEKKKAEEL 1721
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1056-1585 3.51e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.13  E-value: 3.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1056 SKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALElhTAKGLLEGFKVEKVDLQEALGKKEES 1135
Cdd:TIGR00606  446 KEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTE--TLKKEVKSLQNEKADLDRKLRKLDQE 523

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1136 EQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLT-----------------------NEAKEREAALQEEVESL 1192
Cdd:TIGR00606  524 MEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTsllgyfpnkkqledwlhskskeiNQTRDRLAKLNKELASL 603

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1193 TRVQWESRKQSEKDRATLLSqmrvleseLEDQLVQHRGC-------AQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAE 1265
Cdd:TIGR00606  604 EQNKNHINNELESKEEQLSS--------YEDKLFDVCGSqdeesdlERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDE 675

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1266 RE------HEREEFQQEIQRLEGQLRQAARPRPpgprdsqcvqldEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQE 1339
Cdd:TIGR00606  676 NQsccpvcQRVFQTEAELQEFISDLQSKLRLAP------------DKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKE 743

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1340 EEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDLLLTTVSRSGLDEAGCPMLPQGSSSRGPEAQPD 1419
Cdd:TIGR00606  744 KEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRT 823

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1420 VTE-RALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKD----KAEEI-------------EQLHEVIEKLQSELSL 1481
Cdd:TIGR00606  824 VQQvNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKtnelKSEKLqigtnlqrrqqfeEQLVELSTEVQSLIRE 903

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1482 MGPKVHEVSdPQAGSLHSELAclRGEGLGGQALRSELQAAQAAKEVFGQLlaDQAHGHSQALEALQQ-----RLQDAEEV 1556
Cdd:TIGR00606  904 IKDAKEQDS-PLETFLEKDQQ--EKEELISSKETSNKKAQDKVNDIKEKV--KNIHGYMKDIENKIQdgkddYLKQKETE 978

                          570       580
                   ....*....|....*....|....*....
gi 755534236  1557 AARHLAELEHCVALREAEVEAMASQIQEF 1585
Cdd:TIGR00606  979 LNTVNAQLEECEKHQEKINEDMRLMRQDI 1007
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 117-577 4.44e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.53  E-value: 4.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   117 SLELEALRLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQeLALLQSRQQCELELLREQHAREKEEMALRSGQ 196
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQ-WKEKRDELNGELSAADAAVAKDRSELEALEDQ 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   197 EAAELKEKLrsemEKNAQTIETLKQdWESErelcLENLRQELSL---KHQSEMEGLQSQFQKELSEQKVELEKIFQAKHE 273
Cdd:pfam12128  331 HGAFLDADI----ETAAADQEQLPS-WQSE----LENLEERLKAltgKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAK 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   274 AEVSLKNLEAQHQAAIKKLQEDLQSEHCQYLQDL-EQKFREKEKAKELELETLQASY-EDLK---AQSQEEIRLLWSQLE 348
Cdd:pfam12128  402 IREARDRQLAVAEDDLQALESELREQLEAGKLEFnEEEYRLKSRLGELKLRLNQATAtPELLlqlENFDERIERAREEQE 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   349 SMKTNREELNGSwdpvLAQASHLEELEHLRSGFAQQQQQERAQHESELEH--------LRVYFEK----------KLKDA 410
Cdd:pfam12128  482 AANAEVERLQSE----LRQARKRRDQASEALRQASRRLEERQSALDELELqlfpqagtLLHFLRKeapdweqsigKVISP 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   411 EKTYQEDLTVFQQRLQEAREDS-------LESTEISSSCVLPEETSGREGKeppdpldlqlgqpkvQESLVEDCQVKLSK 483
Cdd:pfam12128  558 ELLHRTDLDPEVWDGSVGGELNlygvkldLKRIDVPEWAASEEELRERLDK---------------AEEALQSAREKQAA 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   484 AEEKIQQMKEEFQKKEAEWELSREELKrEAEERLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLERS 563
Cdd:pfam12128  623 AEEQLVQANGELEKASREETFARTALK-NARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAW 701

                          490
                   ....*....|....
gi 755534236   564 LMEQQGHLRQLEQE 577
Cdd:pfam12128  702 LEEQKEQKREARTE 715
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 145-519 4.48e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.76  E-value: 4.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   145 EKETALTELREMlnGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLKQDWE 224
Cdd:TIGR02169  171 KKEKALEELEEV--EENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   225 SEREL---------------CLENLRQELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAI 289
Cdd:TIGR02169  249 LEEELeklteeiselekrleEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   290 KKLQEdLQSEHCQYLQDLEQKFREKEKAKElELETLQASYEDLKAQSQE---EIRLLWSQLESMKTNREELNGSWDPVLA 366
Cdd:TIGR02169  329 AEIDK-LLAEIEELEREIEEERKRRDKLTE-EYAELKEELEDLRAELEEvdkEFAETRDELKDYREKLEKLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   367 QASHLEELehlrsgfAQQQQQERAQHESELEHLRvyfekklkdaektyqEDLTVFQQRLQEAREdslestEIssscvlpe 446
Cdd:TIGR02169  407 ELDRLQEE-------LQRLSEELADLNAAIAGIE---------------AKINELEEEKEDKAL------EI-------- 450

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755534236   447 etsgregkeppdpldlqlgqpKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAEERLAS 519
Cdd:TIGR02169  451 ---------------------KKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAS 502
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 119-357 1.24e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.89  E-value: 1.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   119 ELEALRLSLNNMHTAQLELTQANLQKEKETALTEL---REMLNGRRAQelallqsrqqcELELLREQHAREKEEMalRSG 195
Cdd:pfam17380  349 ELERIRQEERKRELERIRQEEIAMEISRMRELERLqmeRQQKNERVRQ-----------ELEAARKVKILEEERQ--RKI 415

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   196 QEAAELKEKLRSEMEkNAQTIETLKQDWESERElcLENLRQElSLKHQSEMEGLQSQfQKELSEQKVELEKIFQAKHEAE 275
Cdd:pfam17380  416 QQQKVEMEQIRAEQE-EARQREVRRLEEERARE--MERVRLE-EQERQQQVERLRQQ-EEERKRKKLELEKEKRDRKRAE 490

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   276 -----VSLKNLEAQHQAAI------KKLQEDLQSEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEirllw 344
Cdd:pfam17380  491 eqrrkILEKELEERKQAMIeeerkrKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEER----- 565

                          250
                   ....*....|...
gi 755534236   345 SQLESMKTNREEL 357
Cdd:pfam17380  566 SRLEAMEREREMM 578
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 134-501 1.87e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 1.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   134 QLELTQANLQKeKETALTELREMLNGRRAQ-ELAllqsrqqcelELLREQHAREKE---EMALRSGQEAAELKEKLRSEM 209
Cdd:TIGR02168  180 KLERTRENLDR-LEDILNELERQLKSLERQaEKA----------ERYKELKAELRElelALLVLRLEELREELEELQEEL 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   210 EKNAQTIETLkQDWESERELCLENLRQElslkhQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAI 289
Cdd:TIGR02168  249 KEAEEELEEL-TAELQELEEKLEELRLE-----VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   290 KKLQEDLQSEHCQylqdleqkfREKEKAKELELETLQASYEDLKAQSQEEIRllwsQLESMKTNREELNgswdpvlaqas 369
Cdd:TIGR02168  323 AQLEELESKLDEL---------AEELAELEEKLEELKEELESLEAELEELEA----ELEELESRLEELE----------- 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   370 hlEELEHLRSGFAqQQQQERAQHESELEHLrvyfEKKLKDAEKTYQEdltvfQQRLQEAREDSLESTEIssscvlpEETS 449
Cdd:TIGR02168  379 --EQLETLRSKVA-QLELQIASLNNEIERL----EARLERLEDRRER-----LQQEIEELLKKLEEAEL-------KELQ 439

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 755534236   450 GREGKEPPDPLDLQLGQPKVQESLvEDCQVKLSKAEEKIQQMKEEFQKKEAE 501
Cdd:TIGR02168  440 AELEELEEELEELQEELERLEEAL-EELREELEEAEQALDAAERELAQLQAR 490
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2367-2600 2.39e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2367 ALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEacarqetqv 2446
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE--------- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2447 QHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRTHKQELgcclQRERE 2526
Cdd:COG4942    92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL----AALRA 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755534236 2527 KAAWLQAELEQLSARVKEQEARKDARRMERRSSRADLDKRKwQRDKETLRELEIQRQRDEHKIEQLQRLVRELR 2600
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKEL-AELAAELAELQQEAEELEALIARLEAEAAAAA 240
PTZ00121 PTZ00121
MAEBL; Provisional
 1054-1377 2.45e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 2.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1054 DSSKQLEEARQLHRCVEREFRHRNEEMAQAMQ-KQQELLERLREESAAKDRLALELHTAKgllEGFKVEKVDLQEALGKK 1132
Cdd:PTZ00121 1525 DEAKKAEEAKKADEAKKAEEKKKADELKKAEElKKAEEKKKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKLY 1601

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1133 EESEQqliLELEDLRKQLQQ--AARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSE-KDRAT 1209
Cdd:PTZ00121 1602 EEEKK---MKAEEAKKAEEAkiKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdKKKAE 1678

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1210 LLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQ---RQFMDDQAAEREHEREEFQQEIQRLEGQLRQ 1286
Cdd:PTZ00121 1679 EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeeNKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK 1758

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1287 AARPRPPGPRDSQCVQLDEEVeLLQEKLREKLDGFNELVIK--KDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELE 1364
Cdd:PTZ00121 1759 IAHLKKEEEKKAEEIRKEKEA-VIEEELDEEDEKRRMEVDKkiKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVAD 1837

                         330
                  ....*....|...
gi 755534236 1365 KQKKSMEELKEKE 1377
Cdd:PTZ00121 1838 SKNMQLEEADAFE 1850
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
144-542 2.84e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.06  E-value: 2.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  144 KEKETALTELREMLNG--RRAQELALLQSR-QQCELELLREQHAREKEEMALRSGQEAAELKEKLRSEMEKNAQTIETLK 220
Cdd:PRK03918  210 NEISSELPELREELEKleKEVKELEELKEEiEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELK 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  221 QDWESERELC---------LENLRQELSlKHQSEMEGLQSQFqKELSEQKVELEKIFQAKHEAEVSLKNLEAQHqaaikK 291
Cdd:PRK03918  290 EKAEEYIKLSefyeeyldeLREIEKRLS-RLEEEINGIEERI-KELEEKEERLEELKKKLKELEKRLEELEERH-----E 362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  292 LQEDLqsehcqyLQDLEQKFREKEKAKELELETLQASYEDL---KAQSQEEIRLLWSQLESMKTNREELNgswdpvlaqa 368
Cdd:PRK03918  363 LYEEA-------KAKKEELERLKKRLTGLTPEKLEKELEELekaKEEIEEEISKITARIGELKKEIKELK---------- 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  369 shlEELEHLRSGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREdsLESTEISSSCVLPEET 448
Cdd:PRK03918  426 ---KAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRE--LEKVLKKESELIKLKE 500

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  449 SGREGKEppdpldlqlgqpkVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAE--ERLASMFLELRE 526
Cdd:PRK03918  501 LAEQLKE-------------LEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEElkKKLAELEKKLDE 567

                         410
                  ....*....|....*.
gi 755534236  527 kAESEKLSIISRFEHR 542
Cdd:PRK03918  568 -LEEELAELLKELEEL 582
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 116-798 3.01e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.97  E-value: 3.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   116 HSLELEALRLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSG 195
Cdd:pfam02463  193 EELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   196 QEAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKElsEQKVELEKIFQAKHEAE 275
Cdd:pfam02463  273 ENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE--KEEIEELEKELKELEIK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   276 VSLKNLEAQHQAAIKKLQEDLQSEHCQYLQDLEQKFREKEKAKELELEtlqasYEDLKAQSQEEIRLLWSQLESMKTNRE 355
Cdd:pfam02463  351 REAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-----LKSEEEKEAQLLLELARQLEDLLKEEK 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   356 ElngswdpvlAQASHLEELEHLRsGFAQQQQQERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLES 435
Cdd:pfam02463  426 K---------EELEILEEEEESI-ELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   436 TEISSSCVLPEETSGREGKEPPDPLDLQLGQ---------PKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSR 506
Cdd:pfam02463  496 EERSQKESKARSGLKVLLALIKDGVGGRIISahgrlgdlgVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   507 EELKREAEERLASMFLELREKAESEKLSIISRFEHRE-SSMRHLQDQQAAQILDLERSLMEQQGHLRQLEQELTRDDLLP 585
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   586 CSQCGQEPAMAQ--EEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAKEQDAFLRDAQEKHNHELQLLQQGHQQQL 663
Cdd:pfam02463  656 EGLAEKSEVKASlsELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKIN 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   664 LALRmELETKHRSELTEQLASSESRRQALLETHVAELQVKHNAEISALEKRHLSNLDELESCYVADVQTIRDEHQQALEL 743
Cdd:pfam02463  736 EELK-LLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 755534236   744 LRAELEEQLQKKESCHREMLTQELENLK--RQHAEELQSVRDSLRMEMSAQHIENGK 798
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELkeEQKLEKLAEEELERLEEEITKEELLQE 871
PTZ00121 PTZ00121
MAEBL; Provisional
 2220-2605 3.46e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 3.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2220 ANELQKtlSKEQETASDVRK----RLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLR---LRYGHVTWSYCGTS 2292
Cdd:PTZ00121 1184 AEEVRK--AEELRKAEDARKaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKaeeERNNEEIRKFEEAR 1261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2293 SASAGRAVLDGKEKELKVVlEELE--SERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLcvALKH 2370
Cdd:PTZ00121 1262 MAHFARRQAAIKAEEARKA-DELKkaEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAA--KKKA 1338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2371 ERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSealQHERLLTEQLSRNSQEACARQETqvqhal 2450
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK---AEEKKKADEAKKKAEEDKKKADE------ 1409

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2451 LRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRthKQELGCCLQREREKAAW 2530
Cdd:PTZ00121 1410 LKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK--KADEAKKKAEEAKKADE 1487

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755534236 2531 LQAELEQlsARVKEQEARKDArrmERRSSRADLDKRKWQRDKETLRELEIQRQRDEHKIEQLQRLVRELRWKEEV 2605
Cdd:PTZ00121 1488 AKKKAEE--AKKKADEAKKAA---EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEEL 1557
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1143-1362 4.28e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 4.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1143 LEDLRKQLQQAARELLTLKEEKSVLWNQKETLTneakEREAALQEevesLTRVQWEsrkqsEKDRATLLSQMRVLESELE 1222
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDALQ----ERREALQR----LAEYSWD-----EIDVASAEREIAELEAELE 678

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1223 DQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQfmddqaaerehEREEFQQEIQRLEGQLRQAARprppgprdsqcvQ 1302
Cdd:COG4913   679 RLDASSDDLAALEEQLEELEAELEELEEELDELKG-----------EIGRLEKELEQAEEELDELQD------------R 735

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1303 LDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEE 1362
Cdd:COG4913   736 LEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 203-532 5.67e-05

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 48.86  E-value: 5.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  203 EKLRSEMEKNAQT--------IETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKELSEQKvelekifqaKHEA 274
Cdd:NF033838   72 SEIQKSLDKRKHTqnvalnkkLSDIKTEYLYELNVLKEKSEAELTSKTKKELDAAFEQFKKDTLEPG---------KKVA 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  275 EVSLKNLEAQHQAAIKKlQEDLQSEHCQYLQDLEQKFREKE-KAKELELETLQAsyEDLKAQSQEEIRLLWSQLESMKtn 353
Cdd:NF033838  143 EATKKVEEAEKKAKDQK-EEDRRNYPTNTYKTLELEIAESDvEVKKAELELVKE--EAKEPRDEEKIKQAKAKVESKK-- 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  354 reelngswdpvlAQASHLEELEHLRsgfaqqqqqERAQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR--LQE-ARE 430
Cdd:NF033838  218 ------------AEATRLEKIKTDR---------EKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRgvLGEpATP 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  431 DSLESTEISSSCVLPEETsgregkePPDPlDLQLGQpKVQESlvedcQVKLSKAEEKIQQMKEEFQK------------- 497
Cdd:NF033838  277 DKKENDAKSSDSSVGEET-------LPSP-SLKPEK-KVAEA-----EKKVEEAKKKAKDQKEEDRRnyptntyktlele 342

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 755534236  498 --------KEAEWELSREELKR-EAEERLAsmflELREKAESEK 532
Cdd:NF033838  343 iaesdvkvKEAELELVKEEAKEpRNEEKIK----QAKAKVESKK 382
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1035-1477 7.90e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.50  E-value: 7.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1035 RRVYQSLSTAVEGLL-EMALDS--SKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTA 1111
Cdd:PRK02224  285 RERLEELEEERDDLLaEAGLDDadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREE 364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1112 KGLLEGfkvEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVES 1191
Cdd:PRK02224  365 AAELES---ELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARER 441

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1192 LTRVQ--WESRK-----QSEKD--RATLLSQMRVLESELEDQLvqhrgcAQLAEEVATLKQQLAALDKHLRSQRQFMDDQ 1262
Cdd:PRK02224  442 VEEAEalLEAGKcpecgQPVEGspHVETIEEDRERVEELEAEL------EDLEEEVEEVEERLERAEDLVEAEDRIERLE 515

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1263 AAEREHEREEFQQEiQRLEGQLRQAARPRppgprdSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEI 1342
Cdd:PRK02224  516 ERREDLEELIAERR-ETIEEKRERAEELR------ERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERI 588

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1343 KRLeETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDL------LLTTVSRSGLDEAgcpmlpQGSSSRGPEA 1416
Cdd:PRK02224  589 ESL-ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKrerkreLEAEFDEARIEEA------REDKERAEEY 661

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755534236 1417 QPDVTE--RALLQHENEVVHRRNSEIDELKSLiENLQENQRQLQkDKAEEIEQLHEVIEKLQS 1477
Cdd:PRK02224  662 LEQVEEklDELREERDDLQAEIGAVENELEEL-EELRERREALE-NRVEALEALYDEAEELES 722
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1071-1382 1.07e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1071 REFRHRNEEMAQAMQKQQELLERLREesaakdrLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQL 1150
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIID-------LEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1151 QQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDqlvqhrg 1230
Cdd:pfam02463  239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD------- 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1231 caqLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLE--GQLRQAARPRPPGPRDSQC---VQLDE 1305
Cdd:pfam02463  312 ---DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEelEKLQEKLEQLEEELLAKKKlesERLSS 388

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755534236  1306 EVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQE 1382
Cdd:pfam02463  389 AAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1070-1375 1.08e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 1.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1070 EREFRHRNEEMAQAMQKQQELLERLREEsaakdrlaleLHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQ 1149
Cdd:pfam12128  599 EEELRERLDKAEEALQSAREKQAAAEEQ----------LVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDK 668

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1150 LQQAarelltLKEEKSVLWNQKETLTNEAKEREAALQEEVEsltrvqwESRKQSEKDRATLLSQMRVLESELEDQLvqhr 1229
Cdd:pfam12128  669 KNKA------LAERKDSANERLNSLEAQLKQLDKKHQAWLE-------EQKEQKREARTEKQAYWQVVEGALDAQL---- 731

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1230 gcAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRPPGPR--DSQCVQLDEEV 1307
Cdd:pfam12128  732 --ALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRyfDWYQETWLQRR 809

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755534236  1308 ELLQEKLREKLDGFNELvikkdfaDQQLLIQEEEIKR----LEETNASIQRQMVQLQEELEKQKKSMEELKE 1375
Cdd:pfam12128  810 PRLATQLSNIERAISEL-------QQQLARLIADTKLrrakLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2304-2606 1.13e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2304 KEKELKVVLEELESERgkgqALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVA-LKHERAAKDNLQKEL 2382
Cdd:pfam02463  171 KKEALKKLIEETENLA----ELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDyLKLNEERIDLLQELL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2383 QIEASRCEALLAQEKGQLSELQKSLEAERSRslELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRAL 2462
Cdd:pfam02463  247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEE--EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2463 ELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRTHKQELGCCLQREREKAAWLQAELEQLSARV 2542
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755534236  2543 KEQEARKDARRMERRSSRADLDKRKWQRDKETLRELEIQRQRDEHKIEQLQRLVRELRWKEEVS 2606
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELK 468
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 199-970 1.14e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 1.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   199 AELKEKLRSEMEKNAQTIETLKQDWESERELCLEnlRQELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSL 278
Cdd:pfam02463  165 SRLKRKKKEALKKLIEETENLAELIIDLEELKLQ--ELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   279 KNLEAQHQAAIKKLQEDLQSEhcQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESmktNREELN 358
Cdd:pfam02463  243 QELLRDEQEEIESSKQEIEKE--EEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD---DEEKLK 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   359 GSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHESELEhlRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLESTEI 438
Cdd:pfam02463  318 ESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEE--EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   439 SSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEA--EWELSREELKREAEER 516
Cdd:pfam02463  396 ELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQElkLLKDELELKKSEDLLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   517 LASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQAAQILDLE-RSLMEQQGHLRQLEQELTRDDLLPCSQCGQEPAM 595
Cdd:pfam02463  476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVgGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   596 AQEEKNGALLREKEDCALQLLMAQNRFLEERKEIMEKFAKEQDAFLRDAQEKhNHELQLLQQGHQQQLLALRMELETKHR 675
Cdd:pfam02463  556 TADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQ-LDKATLEADEDDKRAKVVEGILKDTEL 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   676 SELTEQLASSESRRQALLETHVAELQVKHNAEISALEKRHLSNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQKK 755
Cdd:pfam02463  635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   756 ESCHRE----MLTQELENLKRQHAEELQSVRDSLRMEMSAQHIENGKGPAADLQGAHQQQDPA-MALHNEGHLLVEDGDA 830
Cdd:pfam02463  715 LKLEAEellaDRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAeEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   831 VLRSVDAEGLLHQAGPQELGDAHTVEMQKSQAELAKPQELQASQDQVAQVRDKVFLLNRE-LEECRAELEQLQQRREREN 909
Cdd:pfam02463  795 KLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEeLERLEEEITKEELLQELLL 874

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755534236   910 QEGTTLICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGLLLDHED 970
Cdd:pfam02463  875 KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE 935
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 203-319 1.18e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 47.90  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  203 EKLRSEMEKNAQTIETLKQDweserelcLENLRQELSLKhqseMEGLQSQFQKELSEQKVEL-EKIFQAKHEAEVSLKNL 281
Cdd:PRK00409  526 EELERELEQKAEEAEALLKE--------AEKLKEELEEK----KEKLQEEEDKLLEEAEKEAqQAIKEAKKEADEIIKEL 593

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 755534236  282 EAQHQAAIKKLQE-DLQSEHCQYLQDLEQKFREKEKAKE 319
Cdd:PRK00409  594 RQLQKGGYASVKAhELIEARKRLNKANEKKEKKKKKQKE 632
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1142-1376 1.43e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.70  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1142 ELEDLRKQLQQAARELLTLKEEKSVLwnqkeTLTNEAKEREAALQEEVESLTRVQweSRKQSEKDRATLLSQMRVLESEL 1221
Cdd:COG3206   183 QLPELRKELEEAEAALEEFRQKNGLV-----DLSEEAKLLLQQLSELESQLAEAR--AELAEAEARLAALRAQLGSGPDA 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1222 EDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMddqaaereherEEFQQEIQRLEGQLRQAARprppgprdSQCV 1301
Cdd:COG3206   256 LPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDV-----------IALRAQIAALRAQLQQEAQ--------RILA 316

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755534236 1302 QLDEEVELLQEKLREkldgfnelvikkdfADQQLLIQEEEIKRLeetnASIQRQMVQLQEELEKQKKSMEELKEK 1376
Cdd:COG3206   317 SLEAELEALQAREAS--------------LQAQLAQLEARLAEL----PELEAELRRLEREVEVARELYESLLQR 373
PTZ00121 PTZ00121
MAEBL; Provisional
 136-409 1.49e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  136 ELTQANLQKEKEtaltELREMLNGRRAQELALLQSRQQCELELLREQHAREKEE--MALRSGQEAAELKEKLRSEMEKNA 213
Cdd:PTZ00121 1526 EAKKAEEAKKAD----EAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDknMALRKAEEAKKAEEARIEEVMKLY 1601

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  214 QTIETLKQDWESERElclENLRQELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAIKKLQ 293
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAE---EAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE 1678

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  294 EDLQSEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESMKTNREELNGSWDPVLAQASHLEE 373
Cdd:PTZ00121 1679 EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK 1758

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 755534236  374 LEHLRSGFAQQQQQERAQHES--------ELEHLRVYFEKKLKD 409
Cdd:PTZ00121 1759 IAHLKKEEEKKAEEIRKEKEAvieeeldeEDEKRRMEVDKKIKD 1802
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2291-2548 1.49e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.74  E-value: 1.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2291 TSSASAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRyLQREGQSSRALEELKLSLEKQLAQNNQLCVALKH 2370
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2371 ERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACAR-QETQVQHA 2449
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRlEDLEEQIE 848

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2450 LLRKLKAEKTRALE-LEAMLEKVQKQAAHTQQQLEAQAQERcVELRREKEvsgNLRSAVDALRTHKQELGCCLQREREKA 2528
Cdd:TIGR02168  849 ELSEDIESLAAEIEeLEELIEELESELEALLNERASLEEAL-ALLRSELE---ELSEELRELESKRSELRRELEELREKL 924

                          250       260
                   ....*....|....*....|
gi 755534236  2529 AWLQAELEQLSARVKEQEAR 2548
Cdd:TIGR02168  925 AQLELRLEGLEVRIDNLQER 944
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
852-1452 1.62e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  852 AHTVEMQKSQAELAKPQELQASQDQVAQVRdKVFLLNRELEECRAELEQLQQRRERenqegttlicmLRADLELAQGEgk 931
Cdd:COG4913   259 ELAERYAAARERLAELEYLRAALRLWFAQR-RLELLEAELEELRAELARLEAELER-----------LEARLDALREE-- 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  932 aLRDALRRLLDLFGDTLKAavtLKSRISERAGLLLDHEDAADTSDARLAAAALGDMWSDEGLLEIDRTLPEGAEtssvce 1011
Cdd:COG4913   325 -LDELEAQIRGNGGDRLEQ---LEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLE------ 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1012 isshvcesffispentldceqpirrvyqslstavegllemaldsskqlEEARQLHRCVEREFRHRNEEmAQAMQKQQELL 1091
Cdd:COG4913   395 ------------------------------------------------ALEEELEALEEALAEAEAAL-RDLRRELRELE 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1092 ERLREESAAKDRLALELHTAKGLLEgfkvekvdlqEALGKKEeseqqlilelEDLRkqlqqAARELLTLKEEKS------ 1165
Cdd:COG4913   426 AEIASLERRKSNIPARLLALRDALA----------EALGLDE----------AELP-----FVGELIEVRPEEErwrgai 480

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1166 --VLWNQKETLTNEAkEREAALQEEVESL---TRVQWE-------SRKQSEKDRATLLSQMRVLESELED---QLVQHRG 1230
Cdd:COG4913   481 erVLGGFALTLLVPP-EHYAAALRWVNRLhlrGRLVYErvrtglpDPERPRLDPDSLAGKLDFKPHPFRAwleAELGRRF 559

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1231 CAQLAEEVATLKQQ-----LAALDKHLRSQRQfMDDQAAER---------EHEREEFQQEIQRLEGQLRQAarprppgpr 1296
Cdd:COG4913   560 DYVCVDSPEELRRHpraitRAGQVKGNGTRHE-KDDRRRIRsryvlgfdnRAKLAALEAELAELEEELAEA--------- 629

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1297 DSQCVQLDEEVELLQEKLR--EKLDGFNELVIKKDFADQQLLIQEEEIKRLEETN---ASIQRQMVQLQEELEKQKKSME 1371
Cdd:COG4913   630 EERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAELERLDASSddlAALEEQLEELEAELEELEEELD 709

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1372 ELKEKEILKQENMGDLL-LTTVSRSGLDEAGcpmlPQGSSSRGPEAQPDVTERALLQHENEVVHRRNSEIDELKSLIENL 1450
Cdd:COG4913   710 ELKGEIGRLEKELEQAEeELDELQDRLEAAE----DLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRA 785


                  ..
gi 755534236 1451 QE 1452
Cdd:COG4913   786 EE 787
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 119-722 1.70e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 1.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   119 ELEALRLSLNNMHTAQLELT---------QANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEE 189
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQkelyalaneISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   190 MALRSGQEAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQELSL-KHQSEMEGLQSQFQKELSEQKVELEKIF 268
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLEDRRERLQQEIEELL 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   269 QAKHEAEVSLKNLE-AQHQAAIKKLQEDLQSEHCQY--LQDLEQKFREKEKAKELELETLQASYEDLKAQsQEEIRLLWS 345
Cdd:TIGR02168  428 KKLEEAELKELQAElEELEEELEELQEELERLEEALeeLREELEEAEQALDAAERELAQLQARLDSLERL-QENLEGFSE 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   346 QLESMKTNREELNGSWDPVLAQ---------------------------------ASHLEELEHLRSGFAQQQQQERAQH 392
Cdd:TIGR02168  507 GVKALLKNQSGLSGILGVLSELisvdegyeaaieaalggrlqavvvenlnaakkaIAFLKQNELGRVTFLPLDSIKGTEI 586

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   393 ESELEHLR-------------VYFEKKLKDAeKTYQEDLTVFQQRLQEAREDSLESTEISSSCVLPEETSGREG-----K 454
Cdd:TIGR02168  587 QGNDREILkniegflgvakdlVKFDPKLRKA-LSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGvitggS 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   455 EPPDPLDLQLGQP--------KVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWE------------LSREELKREAE 514
Cdd:TIGR02168  666 AKTNSSILERRREieeleekiEELEEKIAELEKALAELRKELEELEEELEQLRKELEelsrqisalrkdLARLEAEVEQL 745

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   515 E----RLASMFLELREKAESEKLSIISRFEHRESSMRHLQDQQaAQILDLERSLMEQQGHLRQLEQELTRDdllpcsqcg 590
Cdd:TIGR02168  746 EeriaQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE-AQIEQLKEELKALREALDELRAELTLL--------- 815

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   591 QEPAMAQEEKNGALLREKEDCALQLLMAQNRfLEERKEIMEKFAKEQDAfLRDAQEKhnHELQLLQQGHQQQLLALRMEL 670
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATERRLEDLEEQ-IEELSEDIESLAAEIEE-LEELIEE--LESELEALLNERASLEEALAL 891

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....
gi 755534236   671 ETKHRSELTEQLASSESRRQALLE--THVAELQVKHNAEISALEKRHLSNLDEL 722
Cdd:TIGR02168  892 LRSELEELSEELRELESKRSELRRelEELREKLAQLELRLEGLEVRIDNLQERL 945
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1274-1400 2.27e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 46.77  E-value: 2.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1274 QQEIQRLEGQLRQaarprppgprdsqcvqLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQ---EEEIKRLEETNA 1350
Cdd:COG2433   412 EEEIRRLEEQVER----------------LEAEVEELEAELEEKDERIERLERELSEARSEERREirkDREISRLDREIE 475

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 755534236 1351 SIQRQMVQLQEELEKQKKSMEELkeKEILKQENMGDLL----LTTVSRSGLDEA 1400
Cdd:COG2433   476 RLERELEEERERIEELKRKLERL--KELWKLEHSGELVpvkvVEKFTKEAIRRL 527
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1047-1377 3.90e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.48  E-value: 3.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1047 GLLEMALDSSKQLEEARQLhrcvEREFRHRNEEMAQAMQKQQELLERLREE-SAAKDRLALeLHTAKGLLEgfKVEK--- 1122
Cdd:COG3096   282 ELSERALELRRELFGARRQ----LAEEQYRLVEMARELEELSARESDLEQDyQAASDHLNL-VQTALRQQE--KIERyqe 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1123 ------VDLQEALGKKEESEQQLI----------LELEDLRKQL---QQAARELLT-----------LKEEKSVLWNQKE 1172
Cdd:COG3096   355 dleeltERLEEQEEVVEEAAEQLAeaearleaaeEEVDSLKSQLadyQQALDVQQTraiqyqqavqaLEKARALCGLPDL 434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1173 TLTNeAKEREAALQEEVESLTRVQWESRKQ--------SEKDRATLLSQMRVLESELED-------QLVQHRGCAQLAEE 1237
Cdd:COG3096   435 TPEN-AEDYLAAFRAKEQQATEEVLELEQKlsvadaarRQFEKAYELVCKIAGEVERSQawqtareLLRRYRSQQALAQR 513

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1238 VATLKQQLAALDKHLRSqrqfmddqaaerehereefQQEIQRLEGQLRQaarprppgpRDSQCVQLDEEVELLQEKlrek 1317
Cdd:COG3096   514 LQQLRAQLAELEQRLRQ-------------------QQNAERLLEEFCQ---------RIGQQLDAAEELEELLAE---- 561

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1318 ldgfnelvikkdfadqqlliQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKE 1377
Cdd:COG3096   562 --------------------LEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARA 601
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 139-583 5.06e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 5.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   139 QANLQKEKETALTELREMLNGRRAQELALLQSRQQCE----------LELLREQHAREKEEMALRSGQEAAELKEKLRSE 208
Cdd:TIGR00618  450 TAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETrkkavvlarlLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRR 529

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   209 MEKNAQTIETLKQDWESERELCLENLRQELSLKHQseMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAA 288
Cdd:TIGR00618  530 MQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQ--MQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE 607

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   289 IKKLQED----LQSEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKAQSQEEIRLLWSQLESMKTNREELNGSwdpv 364
Cdd:TIGR00618  608 DMLACEQhallRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQ---- 683

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   365 lAQASHLEELEHLRSGFAQQQQQERAQHESELEHLRVYFE--KKLKDAEKTYQEDLTVFQQRLQEAREDSLEsteisssc 442
Cdd:TIGR00618  684 -KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEieNASSSLGSDLAAREDALNQSLKELMHQART-------- 754

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   443 VLPEETSGREGKEPPDPLDLQLGQPkvQESLVEDCQVKLSKAEEKIQQMKE---EFQKKEAEWELSREELKREAEERLAS 519
Cdd:TIGR00618  755 VLKARTEAHFNNNEEVTAALQTGAE--LSHLAAEIQFFNRLREEDTHLLKTleaEIGQEIPSDEDILNLQCETLVQEEEQ 832

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755534236   520 MFLELREKAESEkLSIISRFEHRESSMRHLQD--QQAAQILDLERSL--------MEQQGHLRQLEQELTRDDL 583
Cdd:TIGR00618  833 FLSRLEEKSATL-GEITHQLLKYEECSKQLAQltQEQAKIIQLSDKLnginqikiQFDGDALIKFLHEITLYAN 905
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 134-358 5.51e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 5.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   134 QLELTQANlqkekeTALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEmalrsgqeaaelKEKLRSEMEKNA 213
Cdd:TIGR04523  273 QKELEQNN------KKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKK------------LEEIQNQISQNN 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   214 QTIETLKQDweserelcLENLRQELSlkhqsEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAIKKLQ 293
Cdd:TIGR04523  335 KIISQLNEQ--------ISQLKKELT-----NSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQ 401

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755534236   294 EDlqsehcqylQDLEQKFREKEKAKELELETLQASYEDLKAQ---SQEEIRLLWSQLESMKTNREELN 358
Cdd:TIGR04523  402 NQ---------EKLNQQKDEQIKKLQQEKELLEKEIERLKETiikNNSEIKDLTNQDSVKELIIKNLD 460
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1142-1366 5.85e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 5.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1142 ELEDLRKQ------LQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMR 1215
Cdd:COG4913   243 ALEDAREQiellepIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALR 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1216 VLESELEDQLVQHRG--CAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRqaarprpp 1293
Cdd:COG4913   323 EELDELEAQIRGNGGdrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLE-------- 394

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755534236 1294 gprdsqcvQLDEEVELLQEKLREKLDGFNELvikkdfaDQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQ 1366
Cdd:COG4913   395 --------ALEEELEALEEALAEAEAALRDL-------RRELRELEAEIASLERRKSNIPARLLALRDALAEA 452
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1092-1289 6.24e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1092 ERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQK 1171
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1172 ETLTNEAKEREAALQ-----EEVESLtrVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLA 1246
Cdd:COG4942   100 EAQKEELAELLRALYrlgrqPPLALL--LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 755534236 1247 ALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAAR 1289
Cdd:COG4942   178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQ 220
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2124-2436 6.26e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 6.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2124 LGDYNSLVQRLEKVIQEQGDPQKVQDHLclsdrSSLLAEIQALRAQLRMTHLQNQEKLQQLCAALTSTEARGSQREHQLR 2203
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEEL-----TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2204 RQVELLAYKVEQEKCIANELQKTLSKEQETA---SDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLR 2280
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAeelAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2281 yghvtwsyCGTSSASAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREgqSSRALEELKLSLEKQLAQ 2360
Cdd:TIGR02168  386 --------SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEE 455

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755534236  2361 NNQLCVALKHERAAKDNLQKELQIEASRcealLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQ 2436
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERE----LAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSE 527
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1146-1484 6.57e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 6.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1146 LRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWEsRKQSEKDRATLLSQMRVLESELEdql 1225
Cdd:TIGR02169  672 EPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKE-IEQLEQEEEKLKERLEELEEDLS--- 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1226 vqhrgcaQLAEEVATLKQQLAALDKHL-RSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQaarprppgprdsqcvqLD 1304
Cdd:TIGR02169  748 -------SLEQEIENVKSELKELEARIeELEEDLHKLEEALNDLEARLSHSRIPEIQAELSK----------------LE 804

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1305 EEVELLQEKLREKLDGFNELVIKKDFAdqqlliqEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENM 1384
Cdd:TIGR02169  805 EEVSRIEARLREIEQKLNRLTLEKEYL-------EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL 877

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1385 GDLlltTVSRSGLDEagcpmlpqgsSSRGPEAQPDVTERAlLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAEE 1464
Cdd:TIGR02169  878 RDL---ESRLGDLKK----------ERDELEAQLRELERK-IEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGED 943

                          330       340
                   ....*....|....*....|....*....
gi 755534236  1465 ---------IEQLHEVIEKLQSELSLMGP 1484
Cdd:TIGR02169  944 eeipeeelsLEDVQAELQRVEEEIRALEP 972
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1182-1593 7.95e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 7.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1182 EAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFmdD 1261
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL--L 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1262 QAAEREHEREEFQQEIQRLEGQLRQA-ARPRPPGPRDSQCVQLDEEVELLQEKLREKLDGFNeLVIKKDFADQQLLIQE- 1339
Cdd:COG4717   126 QLLPLYQELEALEAELAELPERLEELeERLEELRELEEELEELEAELAELQEELEELLEQLS-LATEEELQDLAEELEEl 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1340 -EEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQE---------------NMGDLLLTTVSRSGLDEAGCP 1403
Cdd:COG4717   205 qQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEArlllliaaallallgLGGSLLSLILTIAGVLFLVLG 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1404 MLPQGSSSRGPEAQPDVTERALLQHENEVVHRRNSEIDELKS---LIENLQENQRQLQKDKAEEIEQLHEVIEKLQSELS 1480
Cdd:COG4717   285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAalgLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1481 LMGPKVHEVSDPQAGSLHSElaclrgeglggQALRSELQAAQAAKEVFGQLLADQAHGHSQALEALQQRLQDAEEVAARH 1560
Cdd:COG4717   365 LEELEQEIAALLAEAGVEDE-----------EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE 433

                         410       420       430
                  ....*....|....*....|....*....|...
gi 755534236 1561 LAELEHCVALREAEVEAMASQIQEFAATLKAKE 1593
Cdd:COG4717   434 LEELEEELEELEEELEELREELAELEAELEQLE 466
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1302-1477 8.38e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 8.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1302 QLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELkEKEILKQ 1381
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL-RAELEAQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1382 ENMGDLLLTTVSRSGLDEAGCPMLPQGSSSRGpeaqpdVTERALLQHeneVVHRRNSEIDELKSLIENLQENQRQLQKDK 1461
Cdd:COG4942   103 KEELAELLRALYRLGRQPPLALLLSPEDFLDA------VRRLQYLKY---LAPARREQAEELRADLAELAALRAELEAER 173

                         170
                  ....*....|....*.
gi 755534236 1462 AEEIEQLHEVIEKLQS 1477
Cdd:COG4942   174 AELEALLAELEEERAA 189
PTZ00121 PTZ00121
MAEBL; Provisional
 2192-2563 9.22e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 9.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2192 EARGSQREHQLRRQVELLAYKVEQEKcIANELQKTlSKEQETASDVRKRLVVEQNAVQDLKSELHAcKQENTSLLESLDK 2271
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAEEAKKKAEEAK-KADEAKKK-AEEAKKADEAKKKAEEAKKKADEAKKAAEA-KKKADEAKKAEEA 1521

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2272 VQQEVLRlryghvtwsycgtsSASAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELK 2351
Cdd:PTZ00121 1522 KKADEAK--------------KAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK 1587

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2352 LSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALlAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQL 2431
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA-EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2432 SRN-------SQEACARQETQVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSgnlR 2504
Cdd:PTZ00121 1667 AKKaeedkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED---K 1743

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2505 SAVDALRTHKQELGCCLQREREKAAWLQAELEQLSARVKEQEARKD-ARRMERRSSRADL 2563
Cdd:PTZ00121 1744 KKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDeKRRMEVDKKIKDI 1803
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2161-2438 9.70e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 9.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2161 AEIQALRAQLRMTHLQNQEKLQQLCAALTSTEARGSQRE------HQLRRQVELLAYKVEQEKCIANELQKTLSKEQETA 2234
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEqlrkelEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2235 SDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEvlrlryghvtwsycgtssASAGRAVLDGKEKELKvvleE 2314
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE------------------LKALREALDELRAELT----L 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2315 LESERGKgqalqaqQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKELQI---EASRCEA 2391
Cdd:TIGR02168  815 LNEEAAN-------LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAllnERASLEE 887

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 755534236  2392 LLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEA 2438
Cdd:TIGR02168  888 ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL 934
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2453-2608 1.02e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.85  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2453 KLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCV-ELRREKEVSGNLRSAVDALRTHKQELgcclqrerekaawl 2531
Cdd:COG2433   367 EVKARVIRGLSIEEALEELIEKELPEEEPEAEREKEHEErELTEEEEEIRRLEEQVERLEAEVEEL-------------- 432

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2532 QAELEQLSARVKEQEAR-KDARRMERRSSRADldkRKWQRDKETLRELEIQRQRDEHKIEQLQRLVRELR--WKEEVSGG 2608
Cdd:COG2433   433 EAELEEKDERIERLERElSEARSEERREIRKD---REISRLDREIERLERELEEERERIEELKRKLERLKelWKLEHSGE 509
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 176-963 1.05e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   176 LELLREQHAREKEEMALRSgQEAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQElslkHQSEmEGLQSQFQK 255
Cdd:pfam15921   76 IERVLEEYSHQVKDLQRRL-NESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRE----SQSQ-EDLRNQLQN 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   256 ---ELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAIKKLQEDLqsehCQYLQDLEQKFREKEKAKELELETLQASYEDL 332
Cdd:pfam15921  150 tvhELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL----VDFEEASGKKIYEHDSMSTMHFRSLGSAISKI 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   333 KAQSQEEIRLLWSQL----ESMKTNREELNGSWDPVLAQasHLEELEHLRS-------GFAQQQQQERAQHESELEHLRV 401
Cdd:pfam15921  226 LRELDTEISYLKGRIfpveDQLEALKSESQNKIELLLQQ--HQDRIEQLISeheveitGLTEKASSARSQANSIQSQLEI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   402 yFEKKLKDAEKTYQEDLTvfqqrlqearedSLESTEISSSCVLPEETSGREGKEPPDPLDLQLGQPKVQESLVEDCQVKL 481
Cdd:pfam15921  304 -IQEQARNQNSMYMRQLS------------DLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQ 370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   482 SKA--EEKIQQMKEEFQKKEAEWELSREELKREAEERLASmflelrekaeseklSIISRFEHRESSMRHLQDQQAAQILD 559
Cdd:pfam15921  371 ESGnlDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGN--------------SITIDHLRRELDDRNMEVQRLEALLK 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   560 LERSlmEQQGhlrQLEQELTrddllpcsqcgqepamAQEEKNGALLRekedcaLQLLMAQnrfLEERKEIMEKFAKEQDA 639
Cdd:pfam15921  437 AMKS--ECQG---QMERQMA----------------AIQGKNESLEK------VSSLTAQ---LESTKEMLRKVVEELTA 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   640 flrdaqekhnhelqllqqghqqqllaLRMELETKHRSeLTEQLASSESRRQALLEThvaelqvkhNAEISALEKRHLSNL 719
Cdd:pfam15921  487 --------------------------KKMTLESSERT-VSDLTASLQEKERAIEAT---------NAEITKLRSRVDLKL 530

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   720 DELESCyvadvqTIRDEHQQALELLRAELEEQLQKKESChREMLTQELENLkrqhaeelqsvrdslrMEMSAQHIEN-GK 798
Cdd:pfam15921  531 QELQHL------KNEGDHLRNVQTECEALKLQMAEKDKV-IEILRQQIENM----------------TQLVGQHGRTaGA 587

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   799 GPAADLQGAHQQQDPAMALHnEGHLLVEDGDAVLRSVDAEgllhqagpqelgdAHTVEMQKSQAELAKPQELQASQDqVA 878
Cdd:pfam15921  588 MQVEKAQLEKEINDRRLELQ-EFKILKDKKDAKIRELEAR-------------VSDLELEKVKLVNAGSERLRAVKD-IK 652

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   879 QVRDKvfLLNrELEECRAELEQLQQRRE-------RENQEGTTLICMLRADLELAQGEGKALRDALRRLLDLFGDTLKAA 951
Cdd:pfam15921  653 QERDQ--LLN-EVKTSRNELNSLSEDYEvlkrnfrNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVA 729

                          810
                   ....*....|..
gi 755534236   952 VTLKSRISERAG 963
Cdd:pfam15921  730 MGMQKQITAKRG 741
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1032-1369 1.11e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1032 QPIRRVYQSLSTAVEGLLEMALDSS--KQLEEARQLHRCVEREFrhrnEEMAQAMQKQQELLERLREESAAKDRLALELH 1109
Cdd:COG3096   809 QKLQRLHQAFSQFVGGHLAVAFAPDpeAELAALRQRRSELEREL----AQHRAQEQQLRQQLDQLKEQLQLLNKLLPQAN 884

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1110 TakgLLEGFKVEKVD-LQEALGKKEESEQQL------ILELEDLRKQLQ-------QAARELLTLKEEKSVLWNQKETLT 1175
Cdd:COG3096   885 L---LADETLADRLEeLREELDAAQEAQAFIqqhgkaLAQLEPLVAVLQsdpeqfeQLQADYLQAKEQQRRLKQQIFALS 961

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1176 NEAKEREA-ALQEEVESLTrvqwESRKQSEKDRAtllsQMRVLESELEDQLVQHRgcaQLAEEVATLKQQLAALDKHLRS 1254
Cdd:COG3096   962 EVVQRRPHfSYEDAVGLLG----ENSDLNEKLRA----RLEQAEEARREAREQLR---QAQAQYSQYNQVLASLKSSRDA 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1255 QRQFMDDqaaerehereeFQQEIQRLEgqlrqaarprppgprdsqcVQLDEEVEllqEKLREKLDGFNELVI----KKDF 1330
Cdd:COG3096  1031 KQQTLQE-----------LEQELEELG-------------------VQADAEAE---ERARIRRDELHEELSqnrsRRSQ 1077

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 755534236 1331 ADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKS 1369
Cdd:COG3096  1078 LEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAKAG 1116
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1085-1478 1.12e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1085 QKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEK 1164
Cdd:TIGR04523  225 KQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQK 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1165 SVLW------------NQKETLTNEAKEREAA---LQEEVESLTRvqweSRKQSEKDRATLLSQMRVLESELEDQLVQHr 1229
Cdd:TIGR04523  305 EQDWnkelkselknqeKKLEEIQNQISQNNKIisqLNEQISQLKK----ELTNSESENSEKQRELEEKQNEIEKLKKEN- 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1230 gcAQLAEEVATLKQQLAALDKHLRSQR---QFMDDQAAEREHEREEFQQEIQRLEgqlrqaarprppgprdSQCVQLDEE 1306
Cdd:TIGR04523  380 --QSYKQEIKNLESQINDLESKIQNQEklnQQKDEQIKKLQQEKELLEKEIERLK----------------ETIIKNNSE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1307 VELLQEKLREKLDGFNELVIKKDfadqqllIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGD 1386
Cdd:TIGR04523  442 IKDLTNQDSVKELIIKNLDNTRE-------SLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1387 LLlttvsrsgldeagcpmlPQGSSSRgpeaqpdVTERALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKD-KAEEI 1465
Cdd:TIGR04523  515 LT-----------------KKISSLK-------EKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDeKNKEI 570

                          410
                   ....*....|...
gi 755534236  1466 EQLHEVIEKLQSE 1478
Cdd:TIGR04523  571 EELKQTQKSLKKK 583
PRK12704 PRK12704
phosphodiesterase; Provisional
 203-349 1.37e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 1.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  203 EKLRSEMEKNAQTIetLKqdwESERELclENLRQELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNle 282
Cdd:PRK12704   30 EAKIKEAEEEAKRI--LE---EAKKEA--EAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDR-- 100

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755534236  283 aqHQAAIKKLQEDLQSEhcqyLQDLEQKFREKEKaKELELETLQASY----EDLKAQSQEEIR-LLWSQLES 349
Cdd:PRK12704  101 --KLELLEKREEELEKK----EKELEQKQQELEK-KEEELEELIEEQlqelERISGLTAEEAKeILLEKVEE 165
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
176-431 1.44e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  176 LELLREQHAREKEEMAlrsgqEAAELKEKLRSEMEKNAQTIETLKQ---------DWES-ERELclENLRQELS--LKHQ 243
Cdd:COG4913   612 LAALEAELAELEEELA-----EAEERLEALEAELDALQERREALQRlaeyswdeiDVASaEREI--AELEAELErlDASS 684

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  244 SEMEGLQSQF---QKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAAIKKLQEDLQSEHCQYLQDLEQKFREkEKAKEL 320
Cdd:COG4913   685 DDLAALEEQLeelEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAA-ALGDAV 763

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  321 ElETLQASYEDLKAQSQEEIRLLWSQLESMKT--NRE--ELNGSWDPVLAQASH-LEELEHLRsgfaqqqqqeraqhESE 395
Cdd:COG4913   764 E-RELRENLEERIDALRARLNRAEEELERAMRafNREwpAETADLDADLESLPEyLALLDRLE--------------EDG 828

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 755534236  396 LEHlrvyFEKKLKDA-EKTYQEDLTVFQQRLQEARED 431
Cdd:COG4913   829 LPE----YEERFKELlNENSIEFVADLLSKLRRAIRE 861
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1126-1388 1.45e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 44.18  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1126 QEALGKKEESEQQLILELEDLRKQLQQAARELL----TLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWEsrk 1201
Cdd:COG5185   267 LEKLGENAESSKRLNENANNLIKQFENTKEKIAeytkSIDIKKATESLEEQLAAAEAEQELEESKRETETGIQNLTA--- 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1202 QSEKDRATLLSQMRVLESELEdQLVQHRGCAQLAEEVATLKQQLAALDKHL----RSQRQFMDDQAAEREHEREEFQQEI 1277
Cdd:COG5185   344 EIEQGQESLTENLEAIKEEIE-NIVGEVELSKSSEELDSFKDTIESTKESLdeipQNQRGYAQEILATLEDTLKAADRQI 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1278 QRLEGQLRQAARprppgprdsqcvqldeEVELLQEKLREKLDGFNELVIKKDFADQQLLIQE--EEIKRLEETNASIQRQ 1355
Cdd:COG5185   423 EELQRQIEQATS----------------SNEEVSKLLNELISELNKVMREADEESQSRLEEAydEINRSVRSKKEDLNEE 486

                         250       260       270
                  ....*....|....*....|....*....|...
gi 755534236 1356 MVQLQEELEKQKKSMEELKEKEILKQENMGDLL 1388
Cdd:COG5185   487 LTQIESRVSTLKATLEKLRAKLERQLEGVRSKL 519
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1052-1295 1.48e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1052 ALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEgfkvekvDLQEALGK 1131
Cdd:COG4942    15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA-------ALEAELAE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1132 KEESEQQLILELEDLRKQLQQAARELLTLKEEKSVlwnqKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLL 1211
Cdd:COG4942    88 LEKEIAELRAELEAQKEELAELLRALYRLGRQPPL----ALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1212 SQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPR 1291
Cdd:COG4942   164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                  ....
gi 755534236 1292 PPGP 1295
Cdd:COG4942   244 PAAG 247
PRK09039 PRK09039
peptidoglycan -binding protein;
1468-1604 1.83e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.42  E-value: 1.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1468 LHEVIEKLQSELSLMGPKVHEVSD------PQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVFGQLLADQAHGHSQ 1541
Cdd:PRK09039   44 LSREISGKDSALDRLNSQIAELADllslerQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755534236 1542 ALEALQQrlqdaeeVAARHLAElehcVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLEID 1604
Cdd:PRK09039  124 ELDSEKQ-------VSARALAQ----VELLNQQIAALRRQLAALEAALDASEKRDRESQAKIA 175
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1140-1588 2.03e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 2.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1140 ILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLES 1219
Cdd:pfam12128  243 FTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRS 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1220 ELEDQLVQHRgcAQLAEEVATLKQQLAALDKhLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQlrqaarprppgpRDSQ 1299
Cdd:pfam12128  323 ELEALEDQHG--AFLDADIETAAADQEQLPS-WQSELENLEERLKALTGKHQDVTAKYNRRRSK------------IKEQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1300 CVQLDEEVELLQEKLREKLDgfnelvikkdfadqqlliqeeeiKRLEETNASIQRQMVQLQEELEKQKKsmeELKEKEIL 1379
Cdd:pfam12128  388 NNRDIAGIKDKLAKIREARD-----------------------RQLAVAEDDLQALESELREQLEAGKL---EFNEEEYR 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1380 KQENMGDLllttvsrsgldeagcpmlpqgsssRGPEAQPDVTERALLQHEN--EVVHRRNSEIDELKSLIENLQENQRQL 1457
Cdd:pfam12128  442 LKSRLGEL------------------------KLRLNQATATPELLLQLENfdERIERAREEQEAANAEVERLQSELRQA 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1458 QK--DKA-EEIEQLHEVIEKLQSELSlmgpKVHEVSDPQAGSLHSELA------------CLRGEGLGGQALRSELQAAQ 1522
Cdd:pfam12128  498 RKrrDQAsEALRQASRRLEERQSALD----ELELQLFPQAGTLLHFLRkeapdweqsigkVISPELLHRTDLDPEVWDGS 573

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755534236  1523 AAKE--VFG------QLLADQAHGHSQALEALQQRLQDAEEVAARHLAELEHCVALREAEVEAmASQIQEFAAT 1588
Cdd:pfam12128  574 VGGElnLYGvkldlkRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEK-ASREETFART 646
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
119-551 2.11e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  119 ELEALRLSLNNMHTAQLELTQANLQKEK--------ETALTELREMLNGRRAQELALLQSRQQCE-----------LELL 179
Cdd:PRK03918  222 ELEKLEKEVKELEELKEEIEELEKELESlegskrklEEKIRELEERIEELKKEIEELEEKVKELKelkekaeeyikLSEF 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  180 REQHAREKEEMALRSG---QEAAELKEKLRSEMEKNAQTIETLKQDWESERELCLENLRQEL---SLKHQSEMEGLQSQF 253
Cdd:PRK03918  302 YEEYLDELREIEKRLSrleEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeeAKAKKEELERLKKRL 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  254 Q-KELSEQKVELEKIFQAKHEAEV----------SLKNLEAQHQAAIKKLQE----------DLQSEHcqyLQDLEQKFR 312
Cdd:PRK03918  382 TgLTPEKLEKELEELEKAKEEIEEeiskitarigELKKEIKELKKAIEELKKakgkcpvcgrELTEEH---RKELLEEYT 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  313 EKEKAKELELETLQASYEDLKAQ---------SQEEIRLLWSQLESMKTNREELNGSWDPVLAQAShlEELEHLRSGFAQ 383
Cdd:PRK03918  459 AELKRIEKELKEIEEKERKLRKElrelekvlkKESELIKLKELAEQLKELEEKLKKYNLEELEKKA--EEYEKLKEKLIK 536

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  384 -----QQQQERAQHESELEHLRVYFEKKLKDAEktyqEDLTVFQQRLQEAREDSLESTEISSSCVLPEETSGREGKEPPD 458
Cdd:PRK03918  537 lkgeiKSLKKELEKLEELKKKLAELEKKLDELE----EELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEK 612

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  459 PLdlqlgqpKVQESLVEDCQVKLSKAEEKIQQMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISR 538
Cdd:PRK03918  613 EL-------EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEEL 685

                         490
                  ....*....|...
gi 755534236  539 FEHRESSMRHLQD 551
Cdd:PRK03918  686 EKRREEIKKTLEK 698
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1057-1479 3.28e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 3.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1057 KQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLA-----LELHTAKGLLEGFKVEKVDLQEALGK 1131
Cdd:PRK03918  391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPvcgreLTEEHRKELLEEYTAELKRIEKELKE 470

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1132 KEESEQQLILELEDLRKQLQQAaRELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLtrvqwesrkqsEKDRATLL 1211
Cdd:PRK03918  471 IEEKERKLRKELRELEKVLKKE-SELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKL-----------KEKLIKLK 538

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1212 SQMRVLESELEdqlvqhrgcaqlaeEVATLKQQLAALDKHLRSqrqfmddqaaerehereeFQQEIQRLEGQLRQAARpr 1291
Cdd:PRK03918  539 GEIKSLKKELE--------------KLEELKKKLAELEKKLDE------------------LEEELAELLKELEELGF-- 584

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1292 ppgprdsqcvqldEEVELLQEKLREKLDGFNELVIKKDfADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSME 1371
Cdd:PRK03918  585 -------------ESVEELEERLKELEPFYNEYLELKD-AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE 650

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1372 ELKEK-EILKQENMGDLLLTTVSR-SGLDEagcpmlpqgsSSRGPEAQPDVTERAL--LQHENEVVHRRNSEIDELKSLI 1447
Cdd:PRK03918  651 ELEKKySEEEYEELREEYLELSRElAGLRA----------ELEELEKRREEIKKTLekLKEELEEREKAKKELEKLEKAL 720

                         410       420       430
                  ....*....|....*....|....*....|..
gi 755534236 1448 ENLQENQRQLQKDKAEEIEQLHEVIEKLQSEL 1479
Cdd:PRK03918  721 ERVEELREKVKKYKALLKERALSKVGEIASEI 752
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2184-2441 3.40e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 3.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2184 LCAALTSTEARGSQRE-HQLRRQVELLAYKVEQEKCIANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQEN 2262
Cdd:COG4942    13 LAAAAQADAAAEAEAElEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2263 TSLLESLDKVQQEVLRLryghvtwsycgtssasAGRAVLDGKEKELKVVLeelesergkgqalQAQQEEQQLRYLQREGQ 2342
Cdd:COG4942    93 AELRAELEAQKEELAEL----------------LRALYRLGRQPPLALLL-------------SPEDFLDAVRRLQYLKY 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 2343 SSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQ 2422
Cdd:COG4942   144 LAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223

                         250
                  ....*....|....*....
gi 755534236 2423 HERLLTEQLSRNSQEACAR 2441
Cdd:COG4942   224 ELEALIARLEAEAAAAAER 242
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
856-1257 3.73e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 3.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  856 EMQKSQAELAKPQELQASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRERENQEgttlicMLRADLELAQGEGKALRD 935
Cdd:COG4717   180 EELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE------LEAAALEERLKEARLLLL 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  936 ALRRLLDLFGdtlkAAVTLKSRISERAGLLLdhedaadtsdARLAAAALGDMWSDEGLLEIDRTLPEGAETSSVCEISsh 1015
Cdd:COG4717   254 IAAALLALLG----LGGSLLSLILTIAGVLF----------LVLGLLALLFLLLAREKASLGKEAEELQALPALEELE-- 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1016 vcesffispentldcEQPIRRVYQSLSTAVEGLLEMALDSSKQLEEARQLHRCVERefrhrneemaqamQKQQELLERLR 1095
Cdd:COG4717   318 ---------------EEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEE-------------LEEELQLEELE 369

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1096 EESAAkdrlalelhtakgLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTL--KEEKSVLWNQKET 1173
Cdd:COG4717   370 QEIAA-------------LLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELleALDEEELEEELEE 436

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1174 LTNEAKEREAALQEEVESLTRVQWESRKQSEKDRatlLSQMRVLESELEDQLvqhrgcAQLAEEVATLKQQLAALDKHLR 1253
Cdd:COG4717   437 LEEELEELEEELEELREELAELEAELEQLEEDGE---LAELLQELEELKAEL------RELAEEWAALKLALELLEEARE 507


                  ....
gi 755534236 1254 SQRQ 1257
Cdd:COG4717   508 EYRE 511
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1057-1576 5.14e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.65  E-value: 5.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1057 KQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREE----------SAAKDRLALELHTAKGLLEGFKVEKVDLQ 1126
Cdd:TIGR00618  229 KHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIeelraqeavlEETQERINRARKAAPLAAHIKAVTQIEQQ 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1127 EA-----LGKKEESEQQLILELEDLRKQ---LQQAARELLTL--KEEKSVLWNQKETLTNEAKEREAALQEEVESLTRvQ 1196
Cdd:TIGR00618  309 AQrihteLQSKMRSRAKLLMKRAAHVKQqssIEEQRRLLQTLhsQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQ-Q 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1197 WESRKQSEKDRATLLSQMRVL----------ESELEDQLVQHRGCAQLAEEVATLKQQLAA--------LDKHLRSQRQF 1258
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREqatidtrtsaFRDLQGQLAHAKKQQELQQRYAELCAAAITctaqceklEKIHLQESAQS 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1259 MDDQAAEREHEREEFQQ--EIQRLEGQ--LRQAARPRP-----------------PGPRDSQCVQLDEEVELLQE----- 1312
Cdd:TIGR00618  468 LKEREQQLQTKEQIHLQetRKKAVVLArlLELQEEPCPlcgscihpnparqdidnPGPLTRRMQRGEQTYAQLETseedv 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1313 --KLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQ---KKSMEELKEKEILKQENMGDL 1387
Cdd:TIGR00618  548 yhQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLseaEDMLACEQHALLRKLQPEQDL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1388 LLTTVSRSGLDEAGCPMLPQGSSSRGPEAQPDVTERALL--QHENEVVHRRNSEIDELKSLIenlqenqRQLQKDKaEEI 1465
Cdd:TIGR00618  628 QDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSirVLPKELLASRQLALQKMQSEK-------EQLTYWK-EML 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  1466 EQLHEVIEKLQSELSLMGPKVHEVSDpqagSLHSELACLRGEGLGGQALRSELQAAQaaKEVFGQLLADQAHGHSQALEA 1545
Cdd:TIGR00618  700 AQCQTLLRELETHIEEYDREFNEIEN----ASSSLGSDLAAREDALNQSLKELMHQA--RTVLKARTEAHFNNNEEVTAA 773

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 755534236  1546 LQ--QRLQDAE---EVAARHLAELEHCVALREAEVE 1576
Cdd:TIGR00618  774 LQtgAELSHLAaeiQFFNRLREEDTHLLKTLEAEIG 809
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
689-1257 5.41e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 5.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  689 RQALLEthvAELQVKHNAEISALEKRHLSNLDELESCyVADVQTIRDEHQQALELLRAELEEQLQKKeschREMLTQELE 768
Cdd:COG4913   241 HEALED---AREQIELLEPIRELAERYAAARERLAEL-EYLRAALRLWFAQRRLELLEAELEELRAE----LARLEAELE 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  769 NLKRQHaEELQSVRDSLRmemsAQHIENGkgpAADLQGAHQQQDpamalhnegHLLVEDGDAVLRSVDAEGLLHQAGPQE 848
Cdd:COG4913   313 RLEARL-DALREELDELE----AQIRGNG---GDRLEQLEREIE---------RLERELEERERRRARLEALLAALGLPL 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  849 LGDAHTVEMQKSQAELAK---PQELQASQDQVAQVRDKVFLLNRELEECRAELEQLQQRRERENQEGTTLICMLRADLEL 925
Cdd:COG4913   376 PASAEEFAALRAEAAALLealEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGL 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  926 AQGE---------------------GKALRDALRRLL---DLFGDTLKA--AVTLKSRI-SERAGLLLDHEDAADTSDAR 978
Cdd:COG4913   456 DEAElpfvgelievrpeeerwrgaiERVLGGFALTLLvppEHYAAALRWvnRLHLRGRLvYERVRTGLPDPERPRLDPDS 535

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  979 LAaaalgdmwsdeGLLEIDRTLPEGAETSSVCEISSHVC---------ESFFISPENTL---------DCEQPIRRVYQs 1040
Cdd:COG4913   536 LA-----------GKLDFKPHPFRAWLEAELGRRFDYVCvdspeelrrHPRAITRAGQVkgngtrhekDDRRRIRSRYV- 603

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1041 lstaveglleMALDSSKQLEEARQLHRCVEREfRHRNEEMAQAMQKQQELLERLREESAAkdrlalelhtakglLEGFKV 1120
Cdd:COG4913   604 ----------LGFDNRAKLAALEAELAELEEE-LAEAEERLEALEAELDALQERREALQR--------------LAEYSW 658

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1121 EKVDLQEAlgkkeeseQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLT---NEAKEREAALQEEVESLTRVQw 1197
Cdd:COG4913   659 DEIDVASA--------EREIAELEAELERLDASSDDLAALEEQLEELEAELEELEeelDELKGEIGRLEKELEQAEEEL- 729

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1198 eSRKQSEKDRATLLSQmRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQ 1257
Cdd:COG4913   730 -DELQDRLEAAEDLAR-LELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEE 787
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1015-1312 6.00e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 6.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1015 HVCESFFISPENTLDCEQPIRRVYQSLSTAVEGL---LEMALDSSKQLEEARQLHRCVEREFrhrneEMAQAMQKQQELL 1091
Cdd:COG3096   427 ALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELeqkLSVADAARRQFEKAYELVCKIAGEV-----ERSQAWQTARELL 501

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1092 ERLREESAAKDRLalelhtakgllegfkvekvdlqealgkkeeseQQLILELEDLRKQL--QQAARELLtlkEEKSVLWN 1169
Cdd:COG3096   502 RRYRSQQALAQRL--------------------------------QQLRAQLAELEQRLrqQQNAERLL---EEFCQRIG 546

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1170 QKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKDRATLlSQMRVLESELED--------QLVQHRGCAQLAEEVATL 1241
Cdd:COG3096   547 QQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQL-EQLRARIKELAArapawlaaQDALERLREQSGEALADS 625

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755534236 1242 KQQLAALDKHLRSQRQFmddqaaerEHEREEFQQEIQRLEGQLRQAArpRPPGPRDSQCVQLDEEV--ELLQE 1312
Cdd:COG3096   626 QEVTAAMQQLLEREREA--------TVERDELAARKQALESQIERLS--QPGGAEDPRLLALAERLggVLLSE 688
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1071-1228 6.35e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 6.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1071 REFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGfkvekvDLQEALGKKEESEQQLIL-----ELED 1145
Cdd:COG1579    20 DRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLEL------EIEEVEARIKKYEEQLGNvrnnkEYEA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1146 LRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQ---SEKDRATLLSQMRVLESELE 1222
Cdd:COG1579    94 LQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEElaeLEAELEELEAEREELAAKIP 173


                  ....*.
gi 755534236 1223 DQLVQH 1228
Cdd:COG1579   174 PELLAL 179
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1057-1480 6.67e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 6.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1057 KQLEEARQLHRCVEREFrhrnEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESE 1136
Cdd:PRK03918  186 KRTENIEELIKEKEKEL----EEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKI 261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1137 QQL---ILELEDLRKQLQQAARELLTLKEEK------SVLWNQKETLTNEAKEREAALQEEVESLTRVQWESRKQSEKdr 1207
Cdd:PRK03918  262 RELeerIEELKKEIEELEEKVKELKELKEKAeeyiklSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEER-- 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1208 atlLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKH---------------LRSQRQFMDDQAAEREHEREE 1272
Cdd:PRK03918  340 ---LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRltgltpeklekeleeLEKAKEEIEEEISKITARIGE 416

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1273 FQQEIQRLEG---QLRQAARPRPPGPRdsqcvQLDEEVEL-LQEKLREKLDGFNELVIKKDFADQQLLIQEEEI--KRLE 1346
Cdd:PRK03918  417 LKKEIKELKKaieELKKAKGKCPVCGR-----ELTEEHRKeLLEEYTAELKRIEKELKEIEEKERKLRKELRELekVLKK 491

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1347 ETNASIQRQMVQLQEELEKQKKS--MEELKEKEILKQENMGDLLLTTVSRSGLDEAGCPMLPQGSSSRGPEAQPDVTERA 1424
Cdd:PRK03918  492 ESELIKLKELAEQLKELEEKLKKynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEE 571

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 755534236 1425 LLQHENEVVHRRNSEIDELKSLIENLQENQRQL--QKDKAEEIEQLHEVIEKLQSELS 1480
Cdd:PRK03918  572 LAELLKELEELGFESVEELEERLKELEPFYNEYleLKDAEKELEREEKELKKLEEELD 629
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
144-294 7.33e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 7.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  144 KEKETALTELREMLNGRRAQELALLQSRQQCELELLREQHAREKEEMALRSGQ--EAAELKEKLRSEMEKN-AQTIETLK 220
Cdd:COG4913   265 AAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARldALREELDELEAQIRGNgGDRLEQLE 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  221 QD---WESERELCLENLRQ--------ELSLKH-QSEMEGLQSQFQKELSEQKVELEKIFQAKHEAEVSLKNLEAQHQAA 288
Cdd:COG4913   345 REierLERELEERERRRARleallaalGLPLPAsAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL 424


                  ....*.
gi 755534236  289 IKKLQE 294
Cdd:COG4913   425 EAEIAS 430
PRK11281 PRK11281
mechanosensitive channel MscK;
1119-1378 7.89e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 7.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1119 KVEKVDLQEAL---GKKEESEQqlilELEDLRKQLQQAARELLTLKEEksvLWNQKETLTNEAKER---------EAALQ 1186
Cdd:PRK11281   59 KLVQQDLEQTLallDKIDRQKE----ETEQLKQQLAQAPAKLRQAQAE---LEALKDDNDEETRETlstlslrqlESRLA 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1187 EEVESLTRVQWE----------SRKQSEKDRATLLS-QMRVLesELEDQL--VQHRGCAQLAEEVATLKQQLAALDKHLR 1253
Cdd:PRK11281  132 QTLDQLQNAQNDlaeynsqlvsLQTQPERAQAALYAnSQRLQ--QIRNLLkgGKVGGKALRPSQRVLLQAEQALLNAQND 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236 1254 SQRQFMDDQAAEREHEREefqqeiQRLEGQLRQAarprppgprdsqcvQLDEEVELLQEKLREK-LDGFNELVikkdfad 1332
Cdd:PRK11281  210 LQRKSLEGNTQLQDLLQK------QRDYLTARIQ--------------RLEHQLQLLQEAINSKrLTLSEKTV------- 262

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 755534236 1333 QQLLIQEEEIKrlEETNASIQRQM---VQLQEELEKQKKSMEELKEKEI 1378
Cdd:PRK11281  263 QEAQSQDEAAR--IQANPLVAQELeinLQLSQRLLKATEKLNTLTQQNL 309
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2200-2474 8.81e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 8.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2200 HQLRRQVELL---AYKVEQEKCIANEL---QKTLSKeqetasdvrKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQ 2273
Cdd:TIGR02168  196 NELERQLKSLerqAEKAERYKELKAELrelELALLV---------LRLEELREELEELQEELKEAEEELEELTAELQELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2274 QEVLRLRYGHvtwsycgtSSASAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRY---LQREGQSSRALEEL 2350
Cdd:TIGR02168  267 EKLEELRLEV--------SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELeaqLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  2351 KLSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALqherlltEQ 2430
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL-------ER 411

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 755534236  2431 LSRNSQEACARQETQVQHALLRKLKAEKTRALELEAMLEKVQKQ 2474
Cdd:TIGR02168  412 LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEE 455
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
73-399 9.91e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.56  E-value: 9.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236   73 PSCSNTLEGTRGASAAQEQ----EDCELDVTDLQGQQQTQPPPPQTAHSL---ELEALRLSLNNMHTAQLELTQANLQKE 145
Cdd:PRK02224  455 PECGQPVEGSPHVETIEEDrervEELEAELEDLEEEVEEVEERLERAEDLveaEDRIERLEERREDLEELIAERRETIEE 534

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  146 KETALTELREmlngrRAQELallqsrqQCELELLREQhAREKEEMALRSGQEAAELKEKLrsemEKNAQTIETLKQDWES 225
Cdd:PRK02224  535 KRERAEELRE-----RAAEL-------EAEAEEKREA-AAEAEEEAEEAREEVAELNSKL----AELKERIESLERIRTL 597

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  226 ERELclENLRQELS-----LKHQSEMEGLQSQFQKELSEQKVELEKIFQAkheaevslknleaqhqAAIKKLQEDLQSEH 300
Cdd:PRK02224  598 LAAI--ADAEDEIErlrekREALAELNDERRERLAEKRERKRELEAEFDE----------------ARIEEAREDKERAE 659

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534236  301 cQYLQDLEQKFREKEKAKEleletlqasyeDLkaqsQEEIRLLWSQLESMKTNREELNGSWDPVLAQASHLEELEHLRSG 380
Cdd:PRK02224  660 -EYLEQVEEKLDELREERD-----------DL----QAEIGAVENELEELEELRERREALENRVEALEALYDEAEELESM 723

                         330
                  ....*....|....*....
gi 755534236  381 FAQQQQQERAQHESELEHL 399
Cdd:PRK02224  724 YGDLRAELRQRNVETLERM 742
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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