|
Name |
Accession |
Description |
Interval |
E-value |
| aden_kin_iso1 |
TIGR01360 |
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ... |
374-540 |
1.72e-99 |
|
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.
Pssm-ID: 130427 [Multi-domain] Cd Length: 188 Bit Score: 299.42 E-value: 1.72e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 374 RKCKIIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLG 453
Cdd:TIGR01360 1 AKCKIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 454 NTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYE 533
Cdd:TIGR01360 81 TSKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYE 160
|
....*..
gi 755503815 534 RKTQLRK 540
Cdd:TIGR01360 161 TKGKLRK 167
|
|
| ADK |
cd01428 |
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ... |
378-540 |
1.27e-54 |
|
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.
Pssm-ID: 238713 [Multi-domain] Cd Length: 194 Bit Score: 183.21 E-value: 1.27e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 378 IIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMvASLGNTKG 457
Cdd:cd01428 1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERL-KKPDCKKG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 458 FLIDGYPREVKQGEEFGRRI---GDPHLVICMDCSADTMTNRLLQRSQS-------------------SQRGEDGAKSIA 515
Cdd:cd01428 80 FILDGFPRTVDQAEALDELLdegIKPDKVIELDVPDEVLIERILGRRICpvsgrvyhlgkddvtgeplSQRSDDNEETIK 159
|
170 180
....*....|....*....|....*
gi 755503815 516 KRLEAYHRASIPVVTYYERKTQLRK 540
Cdd:cd01428 160 KRLEVYKEQTAPLIDYYKKKGKLVE 184
|
|
| ADK |
cd01428 |
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ... |
134-307 |
8.64e-54 |
|
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.
Pssm-ID: 238713 [Multi-domain] Cd Length: 194 Bit Score: 180.90 E-value: 8.64e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 134 IILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNrkWSLIAKIITNGELAPQETTITEIKQKLMQIPDEE 213
Cdd:cd01428 1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTEL--GKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 214 GIVIDGFPRDVAQALSFEDQIC---TPDLVVFLACANQRLKERLQKRA-------------------EQQGRPDDNLKAT 271
Cdd:cd01428 79 GFILDGFPRTVDQAEALDELLDegiKPDKVIELDVPDEVLIERILGRRicpvsgrvyhlgkddvtgePLSQRSDDNEETI 158
|
170 180 190
....*....|....*....|....*....|....*.
gi 755503815 272 QRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAV 307
Cdd:cd01428 159 KKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
|
|
| UMP_CMP_kin_fam |
TIGR01359 |
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ... |
378-540 |
3.42e-51 |
|
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.
Pssm-ID: 273576 [Multi-domain] Cd Length: 185 Bit Score: 173.71 E-value: 3.42e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 378 IIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSE-SERSKLIRDIMERGDLVPSGVVLELLKEAMVASlGNTK 456
Cdd:TIGR01359 1 VVFVLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKREgSENGSLIESYIKEGKIVPSEVTVELLKKAIQED-GSSK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 457 GFLIDGYPREVKQGEEFGRRIG---DPHLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYE 533
Cdd:TIGR01359 80 KFLIDGFPRNEENLEAWEKLMDnkvNFKFVLFFDCPEETMIKRLLKRGQTSGRVDDNIETLKKRFRTYNEETLPIIEHFE 159
|
....*..
gi 755503815 534 RKTQLRK 540
Cdd:TIGR01359 160 NKGKVKE 166
|
|
| ADK |
pfam00406 |
Adenylate kinase; |
381-535 |
6.13e-49 |
|
Adenylate kinase;
Pssm-ID: 395329 [Multi-domain] Cd Length: 184 Bit Score: 167.87 E-value: 6.13e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 381 LMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVAsLGNTKGFLI 460
Cdd:pfam00406 1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQ-NDCKNGFLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 461 DGYPREVKQGEEFGR---RIGDPHLVICMDCSADTMTNRLLQR---------------------------SQSSQRGEDG 510
Cdd:pfam00406 80 DGFPRTVPQAEALEElleRGIKLDYVIEFDVPDEVLVERLTGRrihpnsgrsyhlefnppkvpgkddvtgEPLVQRSDDN 159
|
170 180
....*....|....*....|....*
gi 755503815 511 AKSIAKRLEAYHRASIPVVTYYERK 535
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
|
|
| aden_kin_iso1 |
TIGR01360 |
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ... |
133-317 |
1.10e-48 |
|
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.
Pssm-ID: 130427 [Multi-domain] Cd Length: 188 Bit Score: 167.30 E-value: 1.10e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 133 KIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKwsLIAKIITNGELAPQETTITEIKQKLMQ-IPD 211
Cdd:TIGR01360 4 KIIFIVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGK--QLQAIMESGDLVPLDTVLDLLKDAMVAaLGT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 212 EEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQE 291
Cdd:TIGR01360 82 SKGFLIDGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAETSGRVDDNEKTIKKRLETYYKATEPVIAYYET 161
|
170 180
....*....|....*....|....*.
gi 755503815 292 KGLIVTFDADRDEDAVFHDISVAVDS 317
Cdd:TIGR01360 162 KGKLRKINAEGTVDDVFLQVCTAIDK 187
|
|
| Adk |
COG0563 |
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ... |
377-540 |
7.71e-41 |
|
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440329 [Multi-domain] Cd Length: 212 Bit Score: 146.81 E-value: 7.71e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 377 KIIfLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMvASLGNTK 456
Cdd:COG0563 2 RII-LLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERL-AQPDCAN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 457 GFLIDGYPREVKQGE-------EFGRRIgdpHLVICMDCSADTMTNRLLQR---------------------------SQ 502
Cdd:COG0563 80 GFILDGFPRTVAQAEaldellaELGIKL---DAVIELDVDDEELVERLSGRrvcpncgatyhvkfnppkvegvcdkcgGE 156
|
170 180 190
....*....|....*....|....*....|....*...
gi 755503815 503 SSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQLRK 540
Cdd:COG0563 157 LVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVE 194
|
|
| PLN02200 |
PLN02200 |
adenylate kinase family protein |
378-540 |
3.22e-39 |
|
adenylate kinase family protein
Pssm-ID: 215125 [Multi-domain] Cd Length: 234 Bit Score: 143.49 E-value: 3.22e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 378 IIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTkg 457
Cdd:PLN02200 45 ITFVLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSDNNK-- 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 458 FLIDGYPREVKQGEEFGRRIG-DPHLVICMDCSADTMTNRLLQRSQSsqRGEDGAKSIAKRLEAYHRASIPVVTYYERKT 536
Cdd:PLN02200 123 FLIDGFPRTEENRIAFERIIGaEPNVVLFFDCPEEEMVKRVLNRNQG--RVDDNIDTIKKRLKVFNALNLPVIDYYSKKG 200
|
....
gi 755503815 537 QLRK 540
Cdd:PLN02200 201 KLYT 204
|
|
| UMP_CMP_kin_fam |
TIGR01359 |
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ... |
134-311 |
8.26e-39 |
|
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.
Pssm-ID: 273576 [Multi-domain] Cd Length: 185 Bit Score: 140.58 E-value: 8.26e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 134 IILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKwSLIAKIITNGELAPQETTITEIKQKLMQIPDEE 213
Cdd:TIGR01359 1 VVFVLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKREGSENG-SLIESYIKEGKIVPSEVTVELLKKAIQEDGSSK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 214 GIVIDGFPRDVAQALSFEDQICT---PDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQ 290
Cdd:TIGR01359 80 KFLIDGFPRNEENLEAWEKLMDNkvnFKFVLFFDCPEETMIKRLLKRGQTSGRVDDNIETLKKRFRTYNEETLPIIEHFE 159
|
170 180
....*....|....*....|.
gi 755503815 291 EKGLIVTFDADRDEDAVFHDI 311
Cdd:TIGR01359 160 NKGKVKEINAEGSVEEVFEDV 180
|
|
| Adk |
COG0563 |
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ... |
133-311 |
6.57e-38 |
|
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440329 [Multi-domain] Cd Length: 212 Bit Score: 138.72 E-value: 6.57e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 133 KIILvIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKwsLIAKIITNGELAPQETTITEIKQKLMQIPDE 212
Cdd:COG0563 2 RIIL-LGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGK--KAKEYMDAGELVPDEIVIGLVKERLAQPDCA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 213 EGIVIDGFPRDVAQALSFEDQIC----TPDLVVFLACANQRLKERLQKRA---------------------------EQQ 261
Cdd:COG0563 79 NGFILDGFPRTVAQAEALDELLAelgiKLDAVIELDVDDEELVERLSGRRvcpncgatyhvkfnppkvegvcdkcggELV 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 755503815 262 GRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDI 311
Cdd:COG0563 159 QRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADI 208
|
|
| adk |
PRK00279 |
adenylate kinase; Reviewed |
379-540 |
4.82e-37 |
|
adenylate kinase; Reviewed
Pssm-ID: 234711 [Multi-domain] Cd Length: 215 Bit Score: 136.82 E-value: 4.82e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 379 IFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMvASLGNTKGF 458
Cdd:PRK00279 3 LILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERL-AQPDCKNGF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 459 LIDGYPREVKQGEEFGRRIGDPHL----VICMDCSADTMTNRLLQR---------------------------SQSSQRG 507
Cdd:PRK00279 82 LLDGFPRTIPQAEALDEMLKELGIkldaVIEIDVPDEELVERLSGRricpacgrtyhvkfnppkvegkcdvcgEELIQRA 161
|
170 180 190
....*....|....*....|....*....|...
gi 755503815 508 EDGAKSIAKRLEAYHRASIPVVTYYERKTQLRK 540
Cdd:PRK00279 162 DDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKK 194
|
|
| adk |
TIGR01351 |
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ... |
135-316 |
9.12e-37 |
|
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Pssm-ID: 273569 [Multi-domain] Cd Length: 210 Bit Score: 135.82 E-value: 9.12e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 135 ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKwsLIAKIITNGELAPQETTITEIKQKLMQIPDEE- 213
Cdd:TIGR01351 2 LVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGK--KAKEYMEKGELVPDEIVNQLVKERLTQNDDNEn 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 214 GIVIDGFPRDVAQALSFEDQIC-TPDLVVFLACANQRLKERLQKR---------------------------AEQQGRPD 265
Cdd:TIGR01351 80 GFILDGFPRTLSQAEALDALLEePIDAVIELDVPDEELVERLSGRricpscgrvyhlkfnppkvpgcddctgELLVQRED 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 755503815 266 DNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISVAVD 316
Cdd:TIGR01351 160 DTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEALK 210
|
|
| PLN02200 |
PLN02200 |
adenylate kinase family protein |
113-311 |
1.22e-36 |
|
adenylate kinase family protein
Pssm-ID: 215125 [Multi-domain] Cd Length: 234 Bit Score: 136.18 E-value: 1.22e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 113 SETAELIEEYEVFDPTRPR-PKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNrkWSLIAKIITNGE 191
Cdd:PLN02200 23 SFSTEIITLEERGSSSKEKtPFITFVLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEH--GAMILNTIKEGK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 192 LAPQETTITEIKQKlMQIPDEEGIVIDGFPRDVAQALSFEDQI-CTPDLVVFLACANQRLKERLQKRaeQQGRPDDNLKA 270
Cdd:PLN02200 101 IVPSEVTVKLIQKE-MESSDNNKFLIDGFPRTEENRIAFERIIgAEPNVVLFFDCPEEEMVKRVLNR--NQGRVDDNIDT 177
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 755503815 271 TQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDI 311
Cdd:PLN02200 178 IKKRLKVFNALNLPVIDYYSKKGKLYTINAVGTVDEIFEQV 218
|
|
| ADK |
pfam00406 |
Adenylate kinase; |
137-292 |
3.29e-36 |
|
Adenylate kinase;
Pssm-ID: 395329 [Multi-domain] Cd Length: 184 Bit Score: 133.20 E-value: 3.29e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 137 VIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKwsLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIV 216
Cdd:pfam00406 1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGK--EAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 217 IDGFPRDVAQALSFED---QICTPDLVVFLACANQRLKERLQKRAEQQ---------------------------GRPDD 266
Cdd:pfam00406 79 LDGFPRTVPQAEALEElleRGIKLDYVIEFDVPDEVLVERLTGRRIHPnsgrsyhlefnppkvpgkddvtgeplvQRSDD 158
|
170 180
....*....|....*....|....*.
gi 755503815 267 NLKATQRRLVNFKQNAAPLVKYFQEK 292
Cdd:pfam00406 159 NEETVKKRLETYHKQTKPLIDYYKKK 184
|
|
| adk |
PRK00279 |
adenylate kinase; Reviewed |
133-318 |
3.72e-35 |
|
adenylate kinase; Reviewed
Pssm-ID: 234711 [Multi-domain] Cd Length: 215 Bit Score: 131.43 E-value: 3.72e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 133 KIILvIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKwsLIAKIITNGELAPQETTITEIKQKLMQIPDE 212
Cdd:PRK00279 2 RLIL-LGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGK--EAKSYMDAGELVPDEIVIGLVKERLAQPDCK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 213 EGIVIDGFPRDVAQALSFEDQIC----TPDLVVFLACANQRLKERLQKRA---------------------------EQQ 261
Cdd:PRK00279 79 NGFLLDGFPRTIPQAEALDEMLKelgiKLDAVIEIDVPDEELVERLSGRRicpacgrtyhvkfnppkvegkcdvcgeELI 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 755503815 262 GRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISVAVDSK 318
Cdd:PRK00279 159 QRADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGKL 215
|
|
| adk |
TIGR01351 |
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ... |
377-538 |
4.32e-34 |
|
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Pssm-ID: 273569 [Multi-domain] Cd Length: 210 Bit Score: 128.51 E-value: 4.32e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 377 KIIFLmGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTK 456
Cdd:TIGR01351 1 RLVLL-GPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDNEN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 457 GFLIDGYPREVKQGEEF--------------------------GRRI------------GDPHLVICMDCSADTMTnrll 498
Cdd:TIGR01351 80 GFILDGFPRTLSQAEALdalleepidavieldvpdeelverlsGRRIcpscgrvyhlkfNPPKVPGCDDCTGELLV---- 155
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 755503815 499 qrsqssQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQL 538
Cdd:TIGR01351 156 ------QREDDTEEVVKKRLEVYKEQTEPLIDYYKKRGIL 189
|
|
| PRK14532 |
PRK14532 |
adenylate kinase; Provisional |
135-318 |
6.82e-32 |
|
adenylate kinase; Provisional
Pssm-ID: 184729 [Multi-domain] Cd Length: 188 Bit Score: 121.47 E-value: 6.82e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 135 ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASS-NRKwslIAKIITNGELAPQETTITEIKQKLMQIPDEE 213
Cdd:PRK14532 3 LILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSElGQR---VKGIMDRGELVSDEIVIALIEERLPEAEAAG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 214 GIVIDGFPRDVAQALSFEDQICTP----DLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYF 289
Cdd:PRK14532 80 GAIFDGFPRTVAQAEALDKMLASRgqkiDVVIRLKVDDEALIERIVKRFEEQGRPDDNPEVFVTRLDAYNAQTAPLLPYY 159
|
170 180
....*....|....*....|....*....
gi 755503815 290 QEKGLIVTFDADRDEDAVFHDISVAVDSK 318
Cdd:PRK14532 160 AGQGKLTEVDGMGSIEAVAASIDAALEGV 188
|
|
| AAA_17 |
pfam13207 |
AAA domain; |
382-514 |
8.94e-31 |
|
AAA domain;
Pssm-ID: 463810 [Multi-domain] Cd Length: 136 Bit Score: 116.57 E-value: 8.94e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 382 MGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESerSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNtKGFLID 461
Cdd:pfam13207 1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERIAEEAGE-GGVIVD 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 755503815 462 GYPREVKQGEEFGR------RIGDPHLVICMDCSADTMTNRLLQRsQSSQRGEDGAKSI 514
Cdd:pfam13207 78 GHPRIKTPAGYLPGlpvevlRELKPDAIILLEADPEEILERRLKD-RTRGRDDDSEEEI 135
|
|
| adk |
PRK02496 |
adenylate kinase; Provisional |
377-538 |
2.39e-29 |
|
adenylate kinase; Provisional
Pssm-ID: 179433 [Multi-domain] Cd Length: 184 Bit Score: 114.46 E-value: 2.39e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 377 KIIFLmGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASlGNTK 456
Cdd:PRK02496 3 RLIFL-GPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQP-DAAN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 457 GFLIDGYPREVKQG---EEFGRRIGDP-HLVICMDCSADTMTNRLLQRSqssqRGEDGAKSIAKRLEAYHRASIPVVTYY 532
Cdd:PRK02496 81 GWILDGFPRKVTQAaflDELLQEIGQSgERVVNLDVPDDVVVERLLARG----RKDDTEEVIRRRLEVYREQTAPLIDYY 156
|
....*.
gi 755503815 533 ERKTQL 538
Cdd:PRK02496 157 RDRQKL 162
|
|
| PRK14527 |
PRK14527 |
adenylate kinase; Provisional |
375-540 |
1.76e-28 |
|
adenylate kinase; Provisional
Pssm-ID: 237745 [Multi-domain] Cd Length: 191 Bit Score: 112.19 E-value: 1.76e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 375 KCKIIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAmVASLGN 454
Cdd:PRK14527 5 KNKVVIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDE-LAGMEP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 455 TKgFLIDGYPREVKQGEEFGR---RIGDPHL-VICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVT 530
Cdd:PRK14527 84 VR-VIFDGFPRTLAQAEALDRlleELGARLLaVVLLEVPDEELIRRIVERARQEGRSDDNEETVRRRQQVYREQTQPLVD 162
|
170
....*....|
gi 755503815 531 YYERKTQLRK 540
Cdd:PRK14527 163 YYEARGHLKR 172
|
|
| PRK14532 |
PRK14532 |
adenylate kinase; Provisional |
379-538 |
6.31e-28 |
|
adenylate kinase; Provisional
Pssm-ID: 184729 [Multi-domain] Cd Length: 188 Bit Score: 110.68 E-value: 6.31e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 379 IFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLGnTKGF 458
Cdd:PRK14532 3 LILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLPEAEA-AGGA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 459 LIDGYPREVKQGEEF-------GRRIgdpHLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTY 531
Cdd:PRK14532 82 IFDGFPRTVAQAEALdkmlasrGQKI---DVVIRLKVDDEALIERIVKRFEEQGRPDDNPEVFVTRLDAYNAQTAPLLPY 158
|
....*..
gi 755503815 532 YERKTQL 538
Cdd:PRK14532 159 YAGQGKL 165
|
|
| PRK14531 |
PRK14531 |
adenylate kinase; Provisional |
375-538 |
1.45e-27 |
|
adenylate kinase; Provisional
Pssm-ID: 172997 [Multi-domain] Cd Length: 183 Bit Score: 109.52 E-value: 1.45e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 375 KCKIIFLmGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASlgN 454
Cdd:PRK14531 2 KQRLLFL-GPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLKAL--N 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 455 TKGFLIDGYPREVKQGEEFgrrigDPHL---------VICMDCSADTMTNRLLQRSqssqRGEDGAKSIAKRLEAYHRAS 525
Cdd:PRK14531 79 SGGWLLDGFPRTVAQAEAL-----EPLLeelkqpieaVVLLELDDAVLIERLLARG----RADDNEAVIRNRLEVYREKT 149
|
170
....*....|...
gi 755503815 526 IPVVTYYERKTQL 538
Cdd:PRK14531 150 APLIDHYRQRGLL 162
|
|
| PRK14527 |
PRK14527 |
adenylate kinase; Provisional |
128-315 |
2.58e-27 |
|
adenylate kinase; Provisional
Pssm-ID: 237745 [Multi-domain] Cd Length: 191 Bit Score: 108.72 E-value: 2.58e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 128 TRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKkiHSASSNRKWSLIAKIITNGELAPQETTITEIKQKLM 207
Cdd:PRK14527 2 TQTKNKVVIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRD--HVARGTELGQRAKPIMEAGDLVPDELILALIRDELA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 208 QIPDEEgIVIDGFPRDVAQA----LSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAA 283
Cdd:PRK14527 80 GMEPVR-VIFDGFPRTLAQAealdRLLEELGARLLAVVLLEVPDEELIRRIVERARQEGRSDDNEETVRRRQQVYREQTQ 158
|
170 180 190
....*....|....*....|....*....|..
gi 755503815 284 PLVKYFQEKGLIVTFDADRDEDAVFHDISVAV 315
Cdd:PRK14527 159 PLVDYYEARGHLKRVDGLGTPDEVYARILKAL 190
|
|
| adk |
PRK02496 |
adenylate kinase; Provisional |
135-315 |
5.19e-27 |
|
adenylate kinase; Provisional
Pssm-ID: 179433 [Multi-domain] Cd Length: 184 Bit Score: 107.91 E-value: 5.19e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 135 ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIhsaSSNRKWSLIAKIITN-GELAPQETTITEIKQKLMQIPDEE 213
Cdd:PRK02496 4 LIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAI---KEQTPLGIKAQGYMDkGELVPDQLVLDLVQERLQQPDAAN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 214 GIVIDGFPRDVAQAlSFEDQICTP-----DLVVFLACANQRLKERLQKRaeqqGRPDDNLKATQRRLVNFKQNAAPLVKY 288
Cdd:PRK02496 81 GWILDGFPRKVTQA-AFLDELLQEigqsgERVVNLDVPDDVVVERLLAR----GRKDDTEEVIRRRLEVYREQTAPLIDY 155
|
170 180
....*....|....*....|....*..
gi 755503815 289 FQEKGLIVTFDADRDEDAVFHDISVAV 315
Cdd:PRK02496 156 YRDRQKLLTIDGNQSVEAVTTELKAAL 182
|
|
| PRK14528 |
PRK14528 |
adenylate kinase; Provisional |
377-540 |
2.56e-26 |
|
adenylate kinase; Provisional
Pssm-ID: 172994 [Multi-domain] Cd Length: 186 Bit Score: 105.86 E-value: 2.56e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 377 KIIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMV-ASLGNt 455
Cdd:PRK14528 2 KNIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIReADCKN- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 456 kGFLIDGYPREVKQGEEFGRRIGDPHL----VICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTY 531
Cdd:PRK14528 81 -GFLLDGFPRTVEQADALDALLKNEGKsidkAINLEVPDGELLKRLLGRAEIEGRADDNEATIKNRLDNYNKKTLPLLDF 159
|
....*....
gi 755503815 532 YERKTQLRK 540
Cdd:PRK14528 160 YAAQKKLSQ 168
|
|
| AAA_17 |
pfam13207 |
AAA domain; |
139-268 |
5.32e-26 |
|
AAA domain;
Pssm-ID: 463810 [Multi-domain] Cd Length: 136 Bit Score: 103.47 E-value: 5.32e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 139 GGPGSGKGTQSLKIAERYGFQYISVGELLRKKIhsasSNRKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIVID 218
Cdd:pfam13207 2 GVPGSGKTTQLKKLAEKLGFPHISAGDLLREEA----KERGLVEDRDEMRKLPLEPQKELQKLAAERIAEEAGEGGVIVD 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 755503815 219 GFPRDVAQALSFED------QICTPDLVVFLACANQRLKERLQKRAEqQGRPDDNL 268
Cdd:pfam13207 78 GHPRIKTPAGYLPGlpvevlRELKPDAIILLEADPEEILERRLKDRT-RGRDDDSE 132
|
|
| PRK14530 |
PRK14530 |
adenylate kinase; Provisional |
135-319 |
7.37e-25 |
|
adenylate kinase; Provisional
Pssm-ID: 237747 [Multi-domain] Cd Length: 215 Bit Score: 102.56 E-value: 7.37e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 135 ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLR--KKIHSASSNRKWSLIAKIITNGELAPQEtTITEIKQKlmQIPDE 212
Cdd:PRK14530 6 ILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRanKQMDISDMDTEYDTPGEYMDAGELVPDA-VVNEIVEE--ALSDA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 213 EGIVIDGFPRDVAQALSFEDqICTPDLVVFLACANQRLKERLQKR----------------AEQQG-----------RPD 265
Cdd:PRK14530 83 DGFVLDGYPRNLEQAEYLES-ITDLDVVLYLDVSEEELVDRLTGRrvcpdcganyhvefnqPEEEGvcdecggeliqRDD 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 755503815 266 DNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISVAVDSKL 319
Cdd:PRK14530 162 DTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQDAIDDAT 215
|
|
| PRK14531 |
PRK14531 |
adenylate kinase; Provisional |
135-300 |
1.01e-23 |
|
adenylate kinase; Provisional
Pssm-ID: 172997 [Multi-domain] Cd Length: 183 Bit Score: 98.34 E-value: 1.01e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 135 ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKWSliAKIITNGELAPQETTITEIKQKlMQIPDEEG 214
Cdd:PRK14531 5 LLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEA--EAVMNRGELVSDALVLAIVESQ-LKALNSGG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 215 IVIDGFPRDVAQALSFE---DQICTP-DLVVFLACANQRLKERLQKRaeqqGRPDDNLKATQRRLVNFKQNAAPLVKYFQ 290
Cdd:PRK14531 82 WLLDGFPRTVAQAEALEpllEELKQPiEAVVLLELDDAVLIERLLAR----GRADDNEAVIRNRLEVYREKTAPLIDHYR 157
|
170
....*....|
gi 755503815 291 EKGLIVTFDA 300
Cdd:PRK14531 158 QRGLLQSVEA 167
|
|
| PRK14530 |
PRK14530 |
adenylate kinase; Provisional |
379-533 |
2.28e-23 |
|
adenylate kinase; Provisional
Pssm-ID: 237747 [Multi-domain] Cd Length: 215 Bit Score: 98.32 E-value: 2.28e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 379 IFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRqeltseSERSKLIRDI----------MERGDLVPSGVVLELLKEAm 448
Cdd:PRK14530 6 ILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALR------ANKQMDISDMdteydtpgeyMDAGELVPDAVVNEIVEEA- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 449 vasLGNTKGFLIDGYPREVKQGEEFgRRIGDPHLVICMDCSADTMTNRLLQRSQSS------------------------ 504
Cdd:PRK14530 79 ---LSDADGFVLDGYPRNLEQAEYL-ESITDLDVVLYLDVSEEELVDRLTGRRVCPdcganyhvefnqpeeegvcdecgg 154
|
170 180 190
....*....|....*....|....*....|..
gi 755503815 505 ---QRGEDGAKSIAKRLEAYHRASIPVVTYYE 533
Cdd:PRK14530 155 eliQRDDDTEETVRERLDVFEENTEPVIEHYR 186
|
|
| PRK13808 |
PRK13808 |
adenylate kinase; Provisional |
379-538 |
6.88e-23 |
|
adenylate kinase; Provisional
Pssm-ID: 172341 [Multi-domain] Cd Length: 333 Bit Score: 99.96 E-value: 6.88e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 379 IFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASlGNTKGF 458
Cdd:PRK13808 3 LILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQP-DAANGF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 459 LIDGYPREVKQGEEFGRRIGDPHL----VICMDCSADTMTNRLLQR-SQSSQRGE-----DGAKSIAKRLEAYHRASIPV 528
Cdd:PRK13808 82 ILDGFPRTVPQAEALDALLKDKQLkldaVVELRVNEGALLARVETRvAEMRARGEevradDTPEVLAKRLASYRAQTEPL 161
|
170
....*....|
gi 755503815 529 VTYYERKTQL 538
Cdd:PRK13808 162 VHYYSEKRKL 171
|
|
| PRK13808 |
PRK13808 |
adenylate kinase; Provisional |
133-299 |
2.19e-22 |
|
adenylate kinase; Provisional
Pssm-ID: 172341 [Multi-domain] Cd Length: 333 Bit Score: 98.42 E-value: 2.19e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 133 KIILvIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNrkwSLIAK-IITNGELAPQETTITEIKQKLMQIPD 211
Cdd:PRK13808 2 RLIL-LGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPV---GLKAKdIMASGGLVPDEVVVGIISDRIEQPDA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 212 EEGIVIDGFPRDVAQALSFE----DQICTPDLVVFLACANQRLKERLQKR-AEQQG-----RPDDNLKATQRRLVNFKQN 281
Cdd:PRK13808 78 ANGFILDGFPRTVPQAEALDallkDKQLKLDAVVELRVNEGALLARVETRvAEMRArgeevRADDTPEVLAKRLASYRAQ 157
|
170
....*....|....*...
gi 755503815 282 AAPLVKYFQEKGLIVTFD 299
Cdd:PRK13808 158 TEPLVHYYSEKRKLLTVD 175
|
|
| PLN02842 |
PLN02842 |
nucleotide kinase |
383-533 |
1.63e-21 |
|
nucleotide kinase
Pssm-ID: 178435 [Multi-domain] Cd Length: 505 Bit Score: 98.01 E-value: 1.63e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 383 GGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTKGFLIDG 462
Cdd:PLN02842 4 GAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDAKEKGWLLDG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 463 YPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQR-----------------------SQSSQRGEDGAKSIAKRLE 519
Cdd:PLN02842 84 YPRSFAQAQSLEKLKIRPDIFILLDVPDEILIDRCVGRrldpvtgkiyhiknfppeseeikARLITRPDDTEEKVKARLQ 163
|
170
....*....|....
gi 755503815 520 AYHRASIPVVTYYE 533
Cdd:PLN02842 164 IYKKNAEAILSTYS 177
|
|
| PRK14528 |
PRK14528 |
adenylate kinase; Provisional |
133-295 |
3.05e-21 |
|
adenylate kinase; Provisional
Pssm-ID: 172994 [Multi-domain] Cd Length: 186 Bit Score: 91.61 E-value: 3.05e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 133 KIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSnrkWSLIAK-IITNGELAPQETTITEIKQKLMQIPD 211
Cdd:PRK14528 2 KNIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTA---MGIEAKrYMDAGDLVPDSVVIGIIKDRIREADC 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 212 EEGIVIDGFPRDVAQALSFEDQI----CTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVK 287
Cdd:PRK14528 79 KNGFLLDGFPRTVEQADALDALLknegKSIDKAINLEVPDGELLKRLLGRAEIEGRADDNEATIKNRLDNYNKKTLPLLD 158
|
....*...
gi 755503815 288 YFQEKGLI 295
Cdd:PRK14528 159 FYAAQKKL 166
|
|
| DD_AK5 |
cd22978 |
dimerization/docking (D/D) domain found in adenylate kinase isoenzyme 5 (AK5) and similar ... |
3-46 |
8.83e-21 |
|
dimerization/docking (D/D) domain found in adenylate kinase isoenzyme 5 (AK5) and similar proteins; AK5 (EC 2.7.4.3/EC 2.7.4.6), also called ATP-AMP transphosphorylase 5, acts as a nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. It is active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. It also displays broad nucleoside diphosphate kinase activity. AK5 contains an N-terminal domain that shows high sequence similarity to the dimerization/docking (D/D) domains of regulatory subunit of cAMP-dependent protein kinase (PKA) and protein DPY-30/SDC1.
Pssm-ID: 438547 Cd Length: 44 Bit Score: 85.28 E-value: 8.83e-21
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 755503815 3 TNDAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVK 46
Cdd:cd22978 1 SEDAKDYLSRKEIPQLFESLMTGLMYNRPDDPIEFLEDCLEKIR 44
|
|
| PLN02674 |
PLN02674 |
adenylate kinase |
377-535 |
1.82e-20 |
|
adenylate kinase
Pssm-ID: 178279 [Multi-domain] Cd Length: 244 Bit Score: 90.71 E-value: 1.82e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 377 KIIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASlGNTK 456
Cdd:PLN02674 32 KRLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKP-SCQK 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 457 GFLIDGYPREVKQGEEF-------GRRIgDPHLVICMDCS--ADTMTNRLLQRSQSS----------------------- 504
Cdd:PLN02674 111 GFILDGFPRTVVQAQKLdemlakqGAKI-DKVLNFAIDDAilEERITGRWIHPSSGRtyhtkfappkvpgvddvtgepli 189
|
170 180 190
....*....|....*....|....*....|.
gi 755503815 505 QRGEDGAKSIAKRLEAYHRASIPVVTYYERK 535
Cdd:PLN02674 190 QRKDDTAAVLKSRLEAFHKQTEPVIDYYAKK 220
|
|
| PLN02842 |
PLN02842 |
nucleotide kinase |
136-335 |
6.77e-20 |
|
nucleotide kinase
Pssm-ID: 178435 [Multi-domain] Cd Length: 505 Bit Score: 93.00 E-value: 6.77e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 136 LVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKWSliAKIITNGELAPQETTITEIKQKLmQIPD--EE 213
Cdd:PLN02842 1 MISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRA--KEFMNSGRLVPDEIVIAMVTGRL-SREDakEK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 214 GIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKR-----------------------AEQQGRPDDNLKA 270
Cdd:PLN02842 78 GWLLDGYPRSFAQAQSLEKLKIRPDIFILLDVPDEILIDRCVGRrldpvtgkiyhiknfppeseeikARLITRPDDTEEK 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755503815 271 TQRRLVNFKQNAAPLVKYFQEkgLIVTFDADRDEDAVFHDISVAVdSKLFPNKEAPMDSSDLDPS 335
Cdd:PLN02842 158 VKARLQIYKKNAEAILSTYSD--IMVKIDGNRPKEVVFEEISSLL-SQIQKDATKMIKTKKASPV 219
|
|
| PLN02459 |
PLN02459 |
probable adenylate kinase |
374-538 |
6.83e-19 |
|
probable adenylate kinase
Pssm-ID: 215253 [Multi-domain] Cd Length: 261 Bit Score: 86.44 E-value: 6.83e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 374 RKCKIIFLmGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLG 453
Cdd:PLN02459 28 RNVNWVFL-GCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEAGEE 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 454 N-TKGFLIDGYPREVKQGEEF------------------------GRRI----GDPHLVICMDCSADTMTNRLLQ----- 499
Cdd:PLN02459 107 EgESGFILDGFPRTVRQAEILegvtdidlvvnlklreevlvekclGRRIcsecGKNFNVADIDLKGEDGRPGIVMppllp 186
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 755503815 500 ----RSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQL 538
Cdd:PLN02459 187 ppecASKLITRADDTEEVVKARLRVYKEESQPVEDFYRKRGKL 229
|
|
| PTZ00088 |
PTZ00088 |
adenylate kinase 1; Provisional |
379-534 |
1.31e-18 |
|
adenylate kinase 1; Provisional
Pssm-ID: 240262 [Multi-domain] Cd Length: 229 Bit Score: 84.85 E-value: 1.31e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 379 IFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASL-GNTKG 457
Cdd:PTZ00088 9 IVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKVTdDCFKG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 458 FLIDGYPREVKQGEEFGrRIGDPHLV------------------ICMDCSADTMTNRLLQRS------------------ 501
Cdd:PTZ00088 89 FILDGFPRNLKQCKELG-KITNIDLFvniylprnilikkllgrrICNTCNRNFNIAHIRSDPydmppilppadcegckgn 167
|
170 180 190
....*....|....*....|....*....|....
gi 755503815 502 -QSSQRGEDGAKSIAKRLEAYHRASIPVVTYYER 534
Cdd:PTZ00088 168 pKLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKN 201
|
|
| PRK14526 |
PRK14526 |
adenylate kinase; Provisional |
377-538 |
7.10e-18 |
|
adenylate kinase; Provisional
Pssm-ID: 172992 [Multi-domain] Cd Length: 211 Bit Score: 82.59 E-value: 7.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 377 KIIFLmGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLkEAMVASLGNTK 456
Cdd:PRK14526 2 KLVFL-GPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIV-EDKINTIKNND 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 457 GFLIDGYPREVKQGEEFGRRIGDPHLV-----------------ICMDC-------SADTMTNRLLQRSQSS--QRGEDG 510
Cdd:PRK14526 80 NFILDGFPRNINQAKALDKFLPNIKIInflideellikrlsgrrICKSCnnifniyTLPTKEKGICDVCKGDlyQRKDDK 159
|
170 180
....*....|....*....|....*...
gi 755503815 511 AKSIAKRLEAYHRASIPVVTYYERKTQL 538
Cdd:PRK14526 160 EESLKTRLQEYKLQTKPLIEFYSKCNRL 187
|
|
| PRK14526 |
PRK14526 |
adenylate kinase; Provisional |
135-307 |
3.27e-14 |
|
adenylate kinase; Provisional
Pssm-ID: 172992 [Multi-domain] Cd Length: 211 Bit Score: 71.81 E-value: 3.27e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 135 ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKWslIAKIITNGELAPQETTITEIKQKLMQIPDEEG 214
Cdd:PRK14526 3 LVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKE--IKQIVENGQLVPDSITIKIVEDKINTIKNNDN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 215 IVIDGFPRDVAQALSFEDQICTPDLVVFLaCANQRLKERLQKR----------------AEQQG-----------RPDDN 267
Cdd:PRK14526 81 FILDGFPRNINQAKALDKFLPNIKIINFL-IDEELLIKRLSGRrickscnnifniytlpTKEKGicdvckgdlyqRKDDK 159
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 755503815 268 LKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAV 307
Cdd:PRK14526 160 EESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKDIDEV 199
|
|
| PTZ00088 |
PTZ00088 |
adenylate kinase 1; Provisional |
131-293 |
7.64e-14 |
|
adenylate kinase 1; Provisional
Pssm-ID: 240262 [Multi-domain] Cd Length: 229 Bit Score: 70.98 E-value: 7.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 131 RPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKwsLIAKIITNGELAPQETTITEIKQKLMQIP 210
Cdd:PTZ00088 5 GPLKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGK--EIQKVVTSGNLVPDNLVIAIVKDEIAKVT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 211 DE--EGIVIDGFPRDVAQALSFEdQICTPDLVVFLACANQRLKERLQKR------------------------------- 257
Cdd:PTZ00088 83 DDcfKGFILDGFPRNLKQCKELG-KITNIDLFVNIYLPRNILIKKLLGRricntcnrnfniahirsdpydmppilppadc 161
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 755503815 258 ------AEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQEKG 293
Cdd:PTZ00088 162 egckgnPKLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNEN 203
|
|
| PLN02674 |
PLN02674 |
adenylate kinase |
128-302 |
4.05e-13 |
|
adenylate kinase
Pssm-ID: 178279 [Multi-domain] Cd Length: 244 Bit Score: 69.14 E-value: 4.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 128 TRPRPKIILvIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIhsaSSNRKWSLIAK-IITNGELAPQETTITEIKQKL 206
Cdd:PLN02674 28 SKPDKRLIL-IGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAV---AAKTPLGIKAKeAMDKGELVSDDLVVGIIDEAM 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 207 MQIPDEEGIVIDGFPRDVAQALSFED----QICTPDLVVFLACANQRLKERLQKR----------------------AEQ 260
Cdd:PLN02674 104 KKPSCQKGFILDGFPRTVVQAQKLDEmlakQGAKIDKVLNFAIDDAILEERITGRwihpssgrtyhtkfappkvpgvDDV 183
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 755503815 261 QGRP-----DDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADR 302
Cdd:PLN02674 184 TGEPliqrkDDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAEK 230
|
|
| PLN02459 |
PLN02459 |
probable adenylate kinase |
108-299 |
1.49e-12 |
|
probable adenylate kinase
Pssm-ID: 215253 [Multi-domain] Cd Length: 261 Bit Score: 67.95 E-value: 1.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 108 SDTDLSETAELIEEYEVF-DPTRPRPKII--LVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIhsASSNRKWSLIA 184
Cdd:PLN02459 2 SERDAKSTSALADDLASAcDRSLAKGRNVnwVFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEI--KSSGPLGAQLK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 185 KIITNGELAPQETTITEIKQKLMQIPD--EEGIVIDGFPRDVAQALSFEDqICTPDLVVFLACANQRLKER-LQKR---- 257
Cdd:PLN02459 80 EIVNQGKLVPDEIIFSLLSKRLEAGEEegESGFILDGFPRTVRQAEILEG-VTDIDLVVNLKLREEVLVEKcLGRRicse 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755503815 258 ------------AEQQGRP---------------------DDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFD 299
Cdd:PLN02459 159 cgknfnvadidlKGEDGRPgivmppllpppecasklitraDDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEFE 233
|
|
| PRK14529 |
PRK14529 |
adenylate kinase; Provisional |
379-471 |
2.59e-12 |
|
adenylate kinase; Provisional
Pssm-ID: 237746 [Multi-domain] Cd Length: 223 Bit Score: 66.67 E-value: 2.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 379 IFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGV----VLELLKEAmvaslgN 454
Cdd:PRK14529 3 ILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDItipmILETLKQD------G 76
|
90
....*....|....*..
gi 755503815 455 TKGFLIDGYPREVKQGE 471
Cdd:PRK14529 77 KNGWLLDGFPRNKVQAE 93
|
|
| DD_TEX55-like |
cd22961 |
dimerization/docking (D/D) domain found in the testis-specific expressed protein 55 (TEX55) ... |
5-44 |
6.53e-12 |
|
dimerization/docking (D/D) domain found in the testis-specific expressed protein 55 (TEX55)-like family; The TEX55-like family includes TEX55, F-box/LRR-repeat protein 13 (FBXL13), adenylate kinase isoenzymes AK5 and AK8, as well as uncharacterized EF-hand calcium-binding domain-containing protein 10 (EFCAB10), and protein VEST-1. TEX55, also called testis-specific conserved cAMP-dependent type II PK-anchoring protein (TSCPA), is a putative A-kinase anchoring protein (AKAP) that is dispensable for male fertility. FBXL13, also called F-box and leucine-rich repeat protein 13, or dynein regulatory complex subunit 6 (DRC6), is a component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. It may also function as a substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. AK5 and AK8 act as nucleoside monophosphate (NMP) kinases that catalyze the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Members of this family contain a conserved helical bundle domain that shows high sequence similarity to the dimerization/docking (D/D) domains of regulatory subunit of cAMP-dependent protein kinase (PKA) and protein DPY-30/SDC1.
Pssm-ID: 438530 Cd Length: 43 Bit Score: 60.12 E-value: 6.53e-12
10 20 30 40
....*....|....*....|....*....|....*....|
gi 755503815 5 DAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQK 44
Cdd:cd22961 3 DAEEYLEKHKIPELFESLLTALLIEKPEDPIEFLIDKLQQ 42
|
|
| PRK14529 |
PRK14529 |
adenylate kinase; Provisional |
135-227 |
2.97e-10 |
|
adenylate kinase; Provisional
Pssm-ID: 237746 [Multi-domain] Cd Length: 223 Bit Score: 60.50 E-value: 2.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 135 ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIhsaSSNRKWSLIAK-IITNGELAPQETTITEIKQKLmQIPDEE 213
Cdd:PRK14529 3 ILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHI---GGGTELGKKAKeYIDRGDLVPDDITIPMILETL-KQDGKN 78
|
90
....*....|....
gi 755503815 214 GIVIDGFPRDVAQA 227
Cdd:PRK14529 79 GWLLDGFPRNKVQA 92
|
|
| DD_FBXL13 |
cd22977 |
dimerization/docking (D/D) domain found in F-box/LRR-repeat protein 13 (FBXL13) and similar ... |
7-45 |
1.16e-07 |
|
dimerization/docking (D/D) domain found in F-box/LRR-repeat protein 13 (FBXL13) and similar proteins; FBXL13, also called F-box and leucine-rich repeat protein 13, or dynein regulatory complex subunit 6 (DRC6), is a component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. It may also function as a substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It contains an N-terminal domain that shows high sequence similarity to the dimerization/docking (D/D) domains of regulatory subunit of cAMP-dependent protein kinase (PKA) and protein DPY-30/SDC1.
Pssm-ID: 438546 Cd Length: 43 Bit Score: 48.32 E-value: 1.16e-07
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 755503815 7 KEYLARRDIPQLFESLLNGL--MCskPEDPIEYLETCLQKV 45
Cdd:cd22977 5 RKYLRKHKLPDVYEALLTGLavMC--PEDPLRFIEEKLKEL 43
|
|
| COG0645 |
COG0645 |
Predicted kinase, contains AAA domain [General function prediction only]; |
379-511 |
3.03e-07 |
|
Predicted kinase, contains AAA domain [General function prediction only];
Pssm-ID: 440410 [Multi-domain] Cd Length: 164 Bit Score: 50.30 E-value: 3.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 379 IFLMGG-PGSGKGTQCEKLAEKYGFTHLST----GELLRQELTSE---SERSKLIRDIMER--GDLVPSG--VVLELlke 446
Cdd:COG0645 1 LILVCGlPGSGKSTLARALAERLGAVRLRSdvvrKRLFGAGLAPLersPEATARTYARLLAlaRELLAAGrsVILDA--- 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755503815 447 amvaslgntkGFLidgYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSQssQRGEDGA 511
Cdd:COG0645 78 ----------TFL---RRAQREAFRALAEEAGAPFVLIWLDAPEEVLRERLEARNA--EGGDSDA 127
|
|
| DD_AK8 |
cd22979 |
dimerization/docking (D/D) domain found in adenylate kinase isoenzyme 8 (AK8) and similar ... |
8-44 |
1.99e-06 |
|
dimerization/docking (D/D) domain found in adenylate kinase isoenzyme 8 (AK8) and similar proteins; AK8 (EC 2.7.4.3/EC 2.7.4.6), also called ATP-AMP transphosphorylase 8, acts as a nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. It has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. It also displays broad nucleoside diphosphate kinase activity. AK8 contains an N-terminal domain that shows high sequence similarity to the dimerization/docking (D/D) domains of regulatory subunit of cAMP-dependent protein kinase (PKA) and protein DPY-30/SDC1.
Pssm-ID: 438548 Cd Length: 45 Bit Score: 44.76 E-value: 1.99e-06
10 20 30
....*....|....*....|....*....|....*..
gi 755503815 8 EYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQK 44
Cdd:cd22979 8 AYAEKHRIFELFQDLLKQLLIHKPEDPLQFLIDYLQK 44
|
|
| DD_EFCAB10 |
cd22976 |
dimerization/docking (D/D) domain found in EF-hand calcium-binding domain-containing protein ... |
5-47 |
2.04e-06 |
|
dimerization/docking (D/D) domain found in EF-hand calcium-binding domain-containing protein 10 (EFCAB10) and similar proteins; The subfamily includes uncharacterized EF-hand calcium-binding domain-containing protein 10 (EFCAB10), which contains an N-terminal domain that shows high sequence similarity to the dimerization/docking (D/D) domains of regulatory subunit of cAMP-dependent protein kinase (PKA) and protein DPY-30/SDC1.
Pssm-ID: 438545 Cd Length: 47 Bit Score: 44.78 E-value: 2.04e-06
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 755503815 5 DAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKE 47
Cdd:cd22976 3 EAEEYLEKHKIPELFENLTSLLLYHRPEDPKAFLIEQLEKLKE 45
|
|
| CMPK |
cd02020 |
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ... |
135-287 |
2.14e-06 |
|
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.
Pssm-ID: 238978 [Multi-domain] Cd Length: 147 Bit Score: 47.48 E-value: 2.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 135 ILVIGGP-GSGKGTQSLKIAERYGFQYISVGELLRKKIHS-ASSNRKWSLIAKIITNgelapqettiteiKQKLMQIPDe 212
Cdd:cd02020 1 IIAIDGPaGSGKSTVAKLLAKKLGLPYLDTGGIRTEEVGKlASEVAAIPEVRKALDE-------------RQRELAKKP- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 213 eGIVIDGfpRDVAqALSFEDqictPDLVVFLAC-----ANQRLKERLQKRAEqqGRPDDNLKATQRR-LVNFKQNAAPLV 286
Cdd:cd02020 67 -GIVLEG--RDIG-TVVFPD----ADLKIFLTAspevrAKRRAKQLQAKGEG--VDLEEILAEIIERdERDSTRYVAPLK 136
|
.
gi 755503815 287 K 287
Cdd:cd02020 137 L 137
|
|
| PRK01184 |
PRK01184 |
flagellar hook-basal body complex protein FliE; |
132-266 |
4.49e-06 |
|
flagellar hook-basal body complex protein FliE;
Pssm-ID: 234914 [Multi-domain] Cd Length: 184 Bit Score: 47.25 E-value: 4.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 132 PKIILVIGGPGSGKGTQSlKIAERYGFQYISVGELLRKKIHSASSNRKWSLIAKIITN-----GELAPQETTITEIKQKL 206
Cdd:PRK01184 1 MKIIGVVGMPGSGKGEFS-KIAREMGIPVVVMGDVIREEVKKRGLEPTDENIGKVAIDlrkelGMDAVAKRTVPKIREKG 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755503815 207 MQIpdeegIVIDGFpRDVAQALSFEDQI-CTPDLVVFLACANQRLkERLQKRaeqqGRPDD 266
Cdd:PRK01184 80 DEV-----VVIDGV-RGDAEVEYFRKEFpEDFILIAIHAPPEVRF-ERLKKR----GRSDD 129
|
|
| CMPK |
cd02020 |
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ... |
378-442 |
4.56e-06 |
|
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.
Pssm-ID: 238978 [Multi-domain] Cd Length: 147 Bit Score: 46.71 E-value: 4.56e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755503815 378 IIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELT---SESERSKLIRDIM---ERGDLVPSGVVLE 442
Cdd:cd02020 1 IIAIDGPAGSGKSTVAKLLAKKLGLPYLDTGGIRTEEVGklaSEVAAIPEVRKALderQRELAKKPGIVLE 71
|
|
| PRK04182 |
PRK04182 |
cytidylate kinase; Provisional |
378-413 |
1.98e-05 |
|
cytidylate kinase; Provisional
Pssm-ID: 235244 [Multi-domain] Cd Length: 180 Bit Score: 45.18 E-value: 1.98e-05
10 20 30
....*....|....*....|....*....|....*.
gi 755503815 378 IIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQ 413
Cdd:PRK04182 2 IITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRE 37
|
|
| PRK04182 |
PRK04182 |
cytidylate kinase; Provisional |
135-169 |
2.26e-05 |
|
cytidylate kinase; Provisional
Pssm-ID: 235244 [Multi-domain] Cd Length: 180 Bit Score: 45.18 E-value: 2.26e-05
10 20 30
....*....|....*....|....*....|....*.
gi 755503815 135 ILVIGG-PGSGKGTQSLKIAERYGFQYISVGELLRK 169
Cdd:PRK04182 2 IITISGpPGSGKTTVARLLAEKLGLKHVSAGEIFRE 37
|
|
| DD_TbAK-like |
cd22981 |
dimerization/docking (D/D) domain found in Trypanosoma brucei adenylate kinase (AK) and ... |
5-44 |
3.80e-05 |
|
dimerization/docking (D/D) domain found in Trypanosoma brucei adenylate kinase (AK) and similar proteins; AK (EC 2.7.4.3), also called ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, or adenylate monophosphate kinase, catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. It plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Members of this subfamily contain an N-terminal domain that shows high sequence similarity to the dimerization/docking (D/D) domains of regulatory subunit of cAMP-dependent protein kinase (PKA) and protein DPY-30/SDC1.
Pssm-ID: 438550 Cd Length: 44 Bit Score: 40.86 E-value: 3.80e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 755503815 5 DAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQK 44
Cdd:cd22981 4 DAQKYLKEKNIPQLFEFLLRHLLLDKPENPLEYLHDLLER 43
|
|
| PRK03839 |
PRK03839 |
putative kinase; Provisional |
134-318 |
1.20e-04 |
|
putative kinase; Provisional
Pssm-ID: 179660 Cd Length: 180 Bit Score: 43.17 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 134 IILVIGGPGSGKGTQSLKIAERYGFQYISVGEL-LRKKIHSassnrkwsliakiITNGELapqETTITEIKQKLMQIPDE 212
Cdd:PRK03839 2 IIAITGTPGVGKTTVSKLLAEKLGYEYVDLTEFaLKKGIGE-------------EKDDEM---EIDFDKLAYFIEEEFKE 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 213 EGIVIDGFprdvaqaLSfedQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKAtqrRLVNfkqnaAPLVKYFQEK 292
Cdd:PRK03839 66 KNVVLDGH-------LS---HLLPVDYVIVLRAHPKIIKERLKERGYSKKKILENVEA---ELVD-----VCLCEALEEK 127
|
170 180
....*....|....*....|....*..
gi 755503815 293 GLIVTFD-ADRDEDAVFHDISVAVDSK 318
Cdd:PRK03839 128 EKVIEVDtTGKTPEEVVEEILELIKSG 154
|
|
| AAA_18 |
pfam13238 |
AAA domain; |
135-272 |
2.29e-04 |
|
AAA domain;
Pssm-ID: 433052 [Multi-domain] Cd Length: 128 Bit Score: 41.26 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 135 ILVIGGPGSGKGTQSLKIAERYGFqYISVGELLRKkihsassnRKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEG 214
Cdd:pfam13238 1 ILITGTPGVGKTTLAKELSKRLGF-GDNVRDLALE--------NGLVLGDDPETRESKRLDEDKLDRLLDLLEENAALEE 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755503815 215 ---IVIDGFPrdvAQALSFEDqicTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQ 272
Cdd:pfam13238 72 ggnLIIDGHL---AELEPERA---KDLVGIVLRASPEELLERLEKRGYEEAKIKENEEAEI 126
|
|
| DD_CrRSP_unchar |
cd22964 |
dimerization/docking (D/D) domain of an uncharacterized subunit found in Chlamydomonas ... |
4-47 |
2.68e-04 |
|
dimerization/docking (D/D) domain of an uncharacterized subunit found in Chlamydomonas reinhardtii radial spoke 1; Flagellar radial spokes contribute to the regulation of dynein arm activity and thus the pattern of flagellar bending. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. This subfamily includes an uncharacterized protein found in Chlamydomonas reinhardtii radial spoke 1. It contains a conserved domain that shows high sequence similarity to the dimerization/docking (D/D) domains of regulatory subunit of cAMP-dependent protein kinase (PKA) and protein DPY-30/SDC1.
Pssm-ID: 438533 Cd Length: 46 Bit Score: 38.75 E-value: 2.68e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 755503815 4 NDAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKE 47
Cdd:cd22964 3 EEKKEYLQQKVINPILEQLVTDLLQEKPEDPVPFMIQWLRKKRS 46
|
|
| DD_VEST1 |
cd22980 |
dimerization/docking (D/D) domain found in protein VEST-1 and similar proteins; VEST-1 (also ... |
9-47 |
4.12e-04 |
|
dimerization/docking (D/D) domain found in protein VEST-1 and similar proteins; VEST-1 (also called protein C8orf34) is an uncharacterized protein which contains an N-terminal domain that shows high sequence similarity to the dimerization/docking (D/D) domains of regulatory subunit of cAMP-dependent protein kinase (PKA) and protein DPY-30/SDC1.
Pssm-ID: 438549 Cd Length: 45 Bit Score: 38.00 E-value: 4.12e-04
10 20 30
....*....|....*....|....*....|....*....
gi 755503815 9 YLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKE 47
Cdd:cd22980 7 YLEKHKIGALFEDLMAKLIRDTPDEPIPYLIKVLQKKAG 45
|
|
| NK |
cd02019 |
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of ... |
378-428 |
5.76e-04 |
|
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.
Pssm-ID: 238977 [Multi-domain] Cd Length: 69 Bit Score: 38.47 E-value: 5.76e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 755503815 378 IIFLMGGPGSGKGTQCEKLAEKYG---FTHLSTGELLRQELTSESERSKLIRDI 428
Cdd:cd02019 1 IIAITGGSGSGKSTVAKKLAEQLGgrsVVVLDEIVILEGLYASYKSRDARIRDL 54
|
|
| Pgk2 |
COG2074 |
2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and ... |
129-315 |
6.36e-04 |
|
2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and metabolism, Lipid transport and metabolism];
Pssm-ID: 441677 Cd Length: 207 Bit Score: 41.47 E-value: 6.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 129 RPRPKIILVIGGPGSGKGTQSLKIAERYGFQYI----SVGELLRK--------KIHsASSNRKW-SLIAKIITNGELAPQ 195
Cdd:COG2074 3 MKRPRIILIGGASGVGKSTIAAELARRLGIPRVistdSIREVMRPiiskelvpTLH-TSSYEAYkSLSEEEIIAGFLDQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 196 ETTITEIKQklMQ---IPDEEGIVIDG---FPRDVAQALSFEDQICtpdLVVFLACANQRLKERLQKRA--EQQGRPDDN 267
Cdd:COG2074 82 EAVSPGIEA--VIeraLKEGESLVIEGvhlVPGFLAELKFNGGNVV---MLVLLVSDEELHRERFYSRAryTHANRPGER 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 755503815 268 LKAtqrrlvNFKQNA---APLVKYFQEKGLIV--TFDADRDEDAVFHDISVAV 315
Cdd:COG2074 157 YLD------HFERIRriqDYLVEQAREHGVPVieNIDLDETVDRILEAITEAF 203
|
|
| CmkB |
COG1102 |
Cytidylate kinase [Nucleotide transport and metabolism]; |
134-219 |
9.57e-04 |
|
Cytidylate kinase [Nucleotide transport and metabolism];
Pssm-ID: 440719 [Multi-domain] Cd Length: 188 Bit Score: 40.58 E-value: 9.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 134 IILVIGG-PGSGKGTQSLKIAERYGFQYISvGELLRKkihsASSNRKWSLI--------AKIITNGELAPQETTITEIKQ 204
Cdd:COG1102 1 MVITISRePGSGGTTIAKRLAEKLGLPLYD-GEILRE----AAKERGLSEEefekldekAPSLLYRDTAEEDEIDRALDK 75
|
90
....*....|....*
gi 755503815 205 KLMQIPDEEGIVIDG 219
Cdd:COG1102 76 VIRELARKGNCVIVG 90
|
|
| DD_TEX55 |
cd22975 |
dimerization/docking (D/D) domain found in testis-specific expressed protein 55 (TEX55) and ... |
6-47 |
2.19e-03 |
|
dimerization/docking (D/D) domain found in testis-specific expressed protein 55 (TEX55) and similar proteins; TEX55, also called testis-specific conserved cAMP-dependent type II PK-anchoring protein (TSCPA), is a putative A-kinase anchoring protein (AKAP) that is dispensable for male fertility. It contains a C-terminal domain that shows high sequence similarity to the dimerization/docking (D/D) domains of regulatory subunit of cAMP-dependent protein kinase (PKA) and protein DPY-30/SDC1.
Pssm-ID: 438544 Cd Length: 50 Bit Score: 36.39 E-value: 2.19e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 755503815 6 AKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKE 47
Cdd:cd22975 7 AVKYLEKHNILQLFQELTAGLVYERPDDPIQFMIDEIEKIIK 48
|
|
| AAA_33 |
pfam13671 |
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ... |
135-285 |
3.50e-03 |
|
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.
Pssm-ID: 463952 [Multi-domain] Cd Length: 143 Bit Score: 38.06 E-value: 3.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 135 ILVIGGPGSGKGTQSLKIAERYGFQYISVgELLRKKIHSASSNRkwslIAKIITNGELAPQetTITEIKQKLMQIPDeeG 214
Cdd:pfam13671 2 ILLVGLPGSGKSTLARRLLEELGAVRLSS-DDERKRLFGEGRPS----ISYYTDATDRTYE--RLHELARIALRAGR--P 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755503815 215 IVIDG---FPRDVAQALS-FEDQICTPDLVVFLACANQrLKERLQKRAEQQGRPDDnlkATQRRLVNFKQNAAPL 285
Cdd:pfam13671 73 VILDAtnlRRDERARLLAlAREYGVPVRIVVFEAPEEV-LRERLAARARAGGDPSD---VPEEVLDRQKARFEPP 143
|
|
| CmkB |
COG1102 |
Cytidylate kinase [Nucleotide transport and metabolism]; |
383-435 |
6.64e-03 |
|
Cytidylate kinase [Nucleotide transport and metabolism];
Pssm-ID: 440719 [Multi-domain] Cd Length: 188 Bit Score: 37.88 E-value: 6.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755503815 383 GGPGSGKGTQCEKLAEKYGFTHLStGELLRQ------------------------ELTSESER-----SKLIRDIMERGD 433
Cdd:COG1102 7 REPGSGGTTIAKRLAEKLGLPLYD-GEILREaakerglseeefekldekapsllyRDTAEEDEidralDKVIRELARKGN 85
|
..
gi 755503815 434 LV 435
Cdd:COG1102 86 CV 87
|
|
| Cmk |
COG0283 |
Cytidylate kinase [Nucleotide transport and metabolism]; |
384-408 |
7.82e-03 |
|
Cytidylate kinase [Nucleotide transport and metabolism];
Pssm-ID: 440052 [Multi-domain] Cd Length: 220 Bit Score: 38.08 E-value: 7.82e-03
10 20
....*....|....*....|....*.
gi 755503815 384 GP-GSGKGTQCEKLAEKYGFTHLSTG 408
Cdd:COG0283 7 GPaGSGKSTVAKALAKRLGYHYLDTG 32
|
|
| |
