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Conserved domains on  [gi|755498843|ref|XP_011237637|]
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midkine isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTN_MK_N super family cl02505
PTN/MK heparin-binding protein family, N-terminal domain;
1-63 8.47e-34

PTN/MK heparin-binding protein family, N-terminal domain;


The actual alignment was detected with superfamily member smart00193:

Pssm-ID: 470593  Cd Length: 80  Bit Score: 111.12  E-value: 8.47e-34
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755498843    1 MGFREGTCGAQTQRVHCKVPCNWKKEFGADCKYKFESWGACDGSTGTKARQGTLKKARYNAQC 63
Cdd:smart00193 18 LGTREGTCGQETRKLKCKIPCNWKKQFGADCKYKFESWGECDANTGLKTRSGTLKKALYNADC 80
 
Name Accession Description Interval E-value
PTN smart00193
Pleiotrophin / midkine family; Heparin-binding domain family.
 1-63 8.47e-34

Pleiotrophin / midkine family; Heparin-binding domain family.


Pssm-ID: 128490  Cd Length: 80  Bit Score: 111.12  E-value: 8.47e-34
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755498843    1 MGFREGTCGAQTQRVHCKVPCNWKKEFGADCKYKFESWGACDGSTGTKARQGTLKKARYNAQC 63
Cdd:smart00193 18 LGTREGTCGQETRKLKCKIPCNWKKQFGADCKYKFESWGECDANTGLKTRSGTLKKALYNADC 80
PTN_MK_C pfam01091
PTN/MK heparin-binding protein family, C-terminal domain;
28-73 3.56e-19

PTN/MK heparin-binding protein family, C-terminal domain;


Pssm-ID: 460059  Cd Length: 65  Bit Score: 73.64  E-value: 3.56e-19
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 755498843  28 GADCKYKFESWGACDGSTGTKARQGTLKKARYNAQCQETIRVTKPC 73
Cdd:pfam01091  1 GADCKYKFGAWGECDPATGTKTRTGTLKKALFNAECQQTVSVTKPC 46
 
Name Accession Description Interval E-value
PTN smart00193
Pleiotrophin / midkine family; Heparin-binding domain family.
 1-63 8.47e-34

Pleiotrophin / midkine family; Heparin-binding domain family.


Pssm-ID: 128490  Cd Length: 80  Bit Score: 111.12  E-value: 8.47e-34
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755498843    1 MGFREGTCGAQTQRVHCKVPCNWKKEFGADCKYKFESWGACDGSTGTKARQGTLKKARYNAQC 63
Cdd:smart00193 18 LGTREGTCGQETRKLKCKIPCNWKKQFGADCKYKFESWGECDANTGLKTRSGTLKKALYNADC 80
PTN_MK_C pfam01091
PTN/MK heparin-binding protein family, C-terminal domain;
28-73 3.56e-19

PTN/MK heparin-binding protein family, C-terminal domain;


Pssm-ID: 460059  Cd Length: 65  Bit Score: 73.64  E-value: 3.56e-19
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 755498843  28 GADCKYKFESWGACDGSTGTKARQGTLKKARYNAQCQETIRVTKPC 73
Cdd:pfam01091  1 GADCKYKFGAWGECDPATGTKTRTGTLKKALFNAECQQTVSVTKPC 46
PTN_MK_N pfam05196
PTN/MK heparin-binding protein family, N-terminal domain;
2-27 1.60e-09

PTN/MK heparin-binding protein family, N-terminal domain;


Pssm-ID: 461582  Cd Length: 57  Bit Score: 48.99  E-value: 1.60e-09
                         10        20
                 ....*....|....*....|....*.
gi 755498843   2 GFREGTCGAQTQRVHCKVPCNWKKEF 27
Cdd:pfam05196 32 GFREGTCKEQTKKIKCKIPCNWKKEF 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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