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Conserved domains on  [gi|568908081|ref|XP_006529171|]
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abnormal spindle-like microcephaly-associated protein homolog isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5022 super family cl34868
Myosin heavy chain [General function prediction only];
82-230 2.22e-08

Myosin heavy chain [General function prediction only];


The actual alignment was detected with superfamily member COG5022:

Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 59.71  E-value: 2.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081   82 LRMLKNEKLAKLQNkSAVLIQAYWRRYSTRKRFLRLKHYSVILQSRIRMKIALTSYKRYLW--ATVTIQRHWRAYLSRKR 159
Cdd:COG5022   733 LAALEDMRDAKLDN-IATRIQRAIRGRYLRRRYLQALKRIKKIQVIQHGFRLRRLVDYELKwrLFIKLQPLLSLLGSRKE 811

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  160 dqqiFRKLKSSSLVIQFMFRRWKRRKLQLQT----KAAVTLQRAFREWHLRKQIR--ERSAVVIQSWYRM---HRELQKY 230
Cdd:COG5022   812 ----YRSYLACIIKLQKTIKREKKLRETEEVefslKAEVLIQKFGRSLKAKKRFSllKKETIYLQSAQRVelaERQLQEL 887
COG5022 super family cl34868
Myosin heavy chain [General function prediction only];
882-1069 4.95e-08

Myosin heavy chain [General function prediction only];


The actual alignment was detected with superfamily member COG5022:

Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 58.55  E-value: 4.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  882 RYLKMRTAALIIQVRYRAYYLGKiqheKYLRTLKAIKTLQAGVRGARVRRtVRKMHF---AATLIQSHFRGHRQQTYFHR 958
Cdd:COG5022   740 RDAKLDNIATRIQRAIRGRYLRR----RYLQALKRIKKIQVIQHGFRLRR-LVDYELkwrLFIKLQPLLSLLGSRKEYRS 814

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  959 LRKAATMVQqrYRAVKEgsaefqrysrlrrsvlliqaafRGLRTRRHLKAMHLAATLIQRRFRTFAMRRKFLSLRKTAIW 1038
Cdd:COG5022   815 YLACIIKLQ--KTIKRE----------------------KKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIY 870

                         170       180       190
                  ....*....|....*....|....*....|.
gi 568908081 1039 IQRQYRARLYAKYSRQqllLEKAVIKIQSSY 1069
Cdd:COG5022   871 LQSAQRVELAERQLQE---LKIDVKSISSLK 898
COG5022 super family cl34868
Myosin heavy chain [General function prediction only];
1004-1172 3.80e-07

Myosin heavy chain [General function prediction only];


The actual alignment was detected with superfamily member COG5022:

Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.47  E-value: 3.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081 1004 RHLKAMHLAATLIQRRFRTFAMRRKFLSLRKTAIWIQRQYRARLYAKYSRQQLLLeKAVIKIQSSYRGWVVRKRVQKMHR 1083
Cdd:COG5022   739 MRDAKLDNIATRIQRAIRGRYLRRRYLQALKRIKKIQVIQHGFRLRRLVDYELKW-RLFIKLQPLLSLLGSRKEYRSYLA 817

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081 1084 AATVIQatfrmhgaYMRYQHLKRASVVIQVhtaaelqRQKHAAVILQAAVRGMKTRSHLKTMHSSATLIQSQFRAFIVRR 1163
Cdd:COG5022   818 CIIKLQ--------KTIKREKKLRETEEVE-------FSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAER 882


                  ....*....
gi 568908081 1164 RFIALRKAA 1172
Cdd:COG5022   883 QLQELKIDV 891
COG5022 super family cl34868
Myosin heavy chain [General function prediction only];
372-518 5.39e-05

Myosin heavy chain [General function prediction only];


The actual alignment was detected with superfamily member COG5022:

Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.54  E-value: 5.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  372 VLASYQKTRS-----SVIVLQSACRGMQARKAFRHALASVIKIQSYYRAYICRKTFQNFK--NATIKLQSIVKMKQSRKQ 444
Cdd:COG5022   732 VLAALEDMRDakldnIATRIQRAIRGRYLRRRYLQALKRIKKIQVIQHGFRLRRLVDYELkwRLFIKLQPLLSLLGSRKE 811

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568908081  445 YLQIRAAALFIQRWYRSQKLASQKRKEYIQVRESCIKlQSHFRGCLVRKQLRLQCKAAISLQSYFRMRTARQRY 518
Cdd:COG5022   812 YRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLI-QKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQL 884
COG5022 super family cl34868
Myosin heavy chain [General function prediction only];
694-825 4.25e-04

Myosin heavy chain [General function prediction only];


The actual alignment was detected with superfamily member COG5022:

Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.45  E-value: 4.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  694 LRHAALVFQAAWKGKMLRRQIARQHQCAALIQSY-----YRMHIQRRKWSimkTAALQIQLCYRAYkvgkEQRHLYLKTK 768
Cdd:COG5022   744 LDNIATRIQRAIRGRYLRRRYLQALKRIKKIQVIqhgfrLRRLVDYELKW---RLFIKLQPLLSLL----GSRKEYRSYL 816

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  769 AAVVTLQ-SAYRGMKVRKRVAEC--HKAAVTIQSKFRAYRTQKKYTTYRTSAIVIQRWYR 825
Cdd:COG5022   817 ACIIKLQkTIKREKKLRETEEVEfsLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQR 876
COG5022 super family cl34868
Myosin heavy chain [General function prediction only];
475-666 1.00e-03

Myosin heavy chain [General function prediction only];


The actual alignment was detected with superfamily member COG5022:

Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.30  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  475 VRESCIKLQSHFRGCLVRKQ-LRLQC--KAAISLQSYFRMRTARQRYLKMcKAALVIQSFYCAYraqiSQRKNFLQVKRA 551
Cdd:COG5022   744 LDNIATRIQRAIRGRYLRRRyLQALKriKKIQVIQHGFRLRRLVDYELKW-RLFIKLQPLLSLL----GSRKEYRSYLAC 818

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  552 AICLQaayrgCKVRRQIKQQSTAAVtiqrvfrghsqrmkyQTMLQSAVKIQRWYRAQKVaydmRIQFLKTREAVVCLQSA 631
Cdd:COG5022   819 IIKLQ-----KTIKREKKLRETEEV---------------EFSLKAEVLIQKFGRSLKA----KKRFSLLKKETIYLQSA 874

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 568908081  632 YRGWQVRQQLRRQHEAAVKIQStfrmaVAQQQYKL 666
Cdd:COG5022   875 QRVELAERQLQELKIDVKSISS-----LKLVNLEL 904
 
Name Accession Description Interval E-value
COG5022 COG5022
Myosin heavy chain [General function prediction only];
82-230 2.22e-08

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 59.71  E-value: 2.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081   82 LRMLKNEKLAKLQNkSAVLIQAYWRRYSTRKRFLRLKHYSVILQSRIRMKIALTSYKRYLW--ATVTIQRHWRAYLSRKR 159
Cdd:COG5022   733 LAALEDMRDAKLDN-IATRIQRAIRGRYLRRRYLQALKRIKKIQVIQHGFRLRRLVDYELKwrLFIKLQPLLSLLGSRKE 811

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  160 dqqiFRKLKSSSLVIQFMFRRWKRRKLQLQT----KAAVTLQRAFREWHLRKQIR--ERSAVVIQSWYRM---HRELQKY 230
Cdd:COG5022   812 ----YRSYLACIIKLQKTIKREKKLRETEEVefslKAEVLIQKFGRSLKAKKRFSllKKETIYLQSAQRVelaERQLQEL 887
COG5022 COG5022
Myosin heavy chain [General function prediction only];
882-1069 4.95e-08

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 58.55  E-value: 4.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  882 RYLKMRTAALIIQVRYRAYYLGKiqheKYLRTLKAIKTLQAGVRGARVRRtVRKMHF---AATLIQSHFRGHRQQTYFHR 958
Cdd:COG5022   740 RDAKLDNIATRIQRAIRGRYLRR----RYLQALKRIKKIQVIQHGFRLRR-LVDYELkwrLFIKLQPLLSLLGSRKEYRS 814

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  959 LRKAATMVQqrYRAVKEgsaefqrysrlrrsvlliqaafRGLRTRRHLKAMHLAATLIQRRFRTFAMRRKFLSLRKTAIW 1038
Cdd:COG5022   815 YLACIIKLQ--KTIKRE----------------------KKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIY 870

                         170       180       190
                  ....*....|....*....|....*....|.
gi 568908081 1039 IQRQYRARLYAKYSRQqllLEKAVIKIQSSY 1069
Cdd:COG5022   871 LQSAQRVELAERQLQE---LKIDVKSISSLK 898
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1004-1172 3.80e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.47  E-value: 3.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081 1004 RHLKAMHLAATLIQRRFRTFAMRRKFLSLRKTAIWIQRQYRARLYAKYSRQQLLLeKAVIKIQSSYRGWVVRKRVQKMHR 1083
Cdd:COG5022   739 MRDAKLDNIATRIQRAIRGRYLRRRYLQALKRIKKIQVIQHGFRLRRLVDYELKW-RLFIKLQPLLSLLGSRKEYRSYLA 817

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081 1084 AATVIQatfrmhgaYMRYQHLKRASVVIQVhtaaelqRQKHAAVILQAAVRGMKTRSHLKTMHSSATLIQSQFRAFIVRR 1163
Cdd:COG5022   818 CIIKLQ--------KTIKREKKLRETEEVE-------FSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAER 882


                  ....*....
gi 568908081 1164 RFIALRKAA 1172
Cdd:COG5022   883 QLQELKIDV 891
COG5022 COG5022
Myosin heavy chain [General function prediction only];
372-518 5.39e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.54  E-value: 5.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  372 VLASYQKTRS-----SVIVLQSACRGMQARKAFRHALASVIKIQSYYRAYICRKTFQNFK--NATIKLQSIVKMKQSRKQ 444
Cdd:COG5022   732 VLAALEDMRDakldnIATRIQRAIRGRYLRRRYLQALKRIKKIQVIQHGFRLRRLVDYELkwRLFIKLQPLLSLLGSRKE 811

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568908081  445 YLQIRAAALFIQRWYRSQKLASQKRKEYIQVRESCIKlQSHFRGCLVRKQLRLQCKAAISLQSYFRMRTARQRY 518
Cdd:COG5022   812 YRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLI-QKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQL 884
COG5022 COG5022
Myosin heavy chain [General function prediction only];
694-825 4.25e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.45  E-value: 4.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  694 LRHAALVFQAAWKGKMLRRQIARQHQCAALIQSY-----YRMHIQRRKWSimkTAALQIQLCYRAYkvgkEQRHLYLKTK 768
Cdd:COG5022   744 LDNIATRIQRAIRGRYLRRRYLQALKRIKKIQVIqhgfrLRRLVDYELKW---RLFIKLQPLLSLL----GSRKEYRSYL 816

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  769 AAVVTLQ-SAYRGMKVRKRVAEC--HKAAVTIQSKFRAYRTQKKYTTYRTSAIVIQRWYR 825
Cdd:COG5022   817 ACIIKLQkTIKREKKLRETEEVEfsLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQR 876
COG5022 COG5022
Myosin heavy chain [General function prediction only];
475-666 1.00e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.30  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  475 VRESCIKLQSHFRGCLVRKQ-LRLQC--KAAISLQSYFRMRTARQRYLKMcKAALVIQSFYCAYraqiSQRKNFLQVKRA 551
Cdd:COG5022   744 LDNIATRIQRAIRGRYLRRRyLQALKriKKIQVIQHGFRLRRLVDYELKW-RLFIKLQPLLSLL----GSRKEYRSYLAC 818

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  552 AICLQaayrgCKVRRQIKQQSTAAVtiqrvfrghsqrmkyQTMLQSAVKIQRWYRAQKVaydmRIQFLKTREAVVCLQSA 631
Cdd:COG5022   819 IIKLQ-----KTIKREKKLRETEEV---------------EFSLKAEVLIQKFGRSLKA----KKRFSLLKKETIYLQSA 874

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 568908081  632 YRGWQVRQQLRRQHEAAVKIQStfrmaVAQQQYKL 666
Cdd:COG5022   875 QRVELAERQLQELKIDVKSISS-----LKLVNLEL 904
 
Name Accession Description Interval E-value
COG5022 COG5022
Myosin heavy chain [General function prediction only];
82-230 2.22e-08

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 59.71  E-value: 2.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081   82 LRMLKNEKLAKLQNkSAVLIQAYWRRYSTRKRFLRLKHYSVILQSRIRMKIALTSYKRYLW--ATVTIQRHWRAYLSRKR 159
Cdd:COG5022   733 LAALEDMRDAKLDN-IATRIQRAIRGRYLRRRYLQALKRIKKIQVIQHGFRLRRLVDYELKwrLFIKLQPLLSLLGSRKE 811

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  160 dqqiFRKLKSSSLVIQFMFRRWKRRKLQLQT----KAAVTLQRAFREWHLRKQIR--ERSAVVIQSWYRM---HRELQKY 230
Cdd:COG5022   812 ----YRSYLACIIKLQKTIKREKKLRETEEVefslKAEVLIQKFGRSLKAKKRFSllKKETIYLQSAQRVelaERQLQEL 887
COG5022 COG5022
Myosin heavy chain [General function prediction only];
882-1069 4.95e-08

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 58.55  E-value: 4.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  882 RYLKMRTAALIIQVRYRAYYLGKiqheKYLRTLKAIKTLQAGVRGARVRRtVRKMHF---AATLIQSHFRGHRQQTYFHR 958
Cdd:COG5022   740 RDAKLDNIATRIQRAIRGRYLRR----RYLQALKRIKKIQVIQHGFRLRR-LVDYELkwrLFIKLQPLLSLLGSRKEYRS 814

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  959 LRKAATMVQqrYRAVKEgsaefqrysrlrrsvlliqaafRGLRTRRHLKAMHLAATLIQRRFRTFAMRRKFLSLRKTAIW 1038
Cdd:COG5022   815 YLACIIKLQ--KTIKRE----------------------KKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIY 870

                         170       180       190
                  ....*....|....*....|....*....|.
gi 568908081 1039 IQRQYRARLYAKYSRQqllLEKAVIKIQSSY 1069
Cdd:COG5022   871 LQSAQRVELAERQLQE---LKIDVKSISSLK 898
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1004-1172 3.80e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.47  E-value: 3.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081 1004 RHLKAMHLAATLIQRRFRTFAMRRKFLSLRKTAIWIQRQYRARLYAKYSRQQLLLeKAVIKIQSSYRGWVVRKRVQKMHR 1083
Cdd:COG5022   739 MRDAKLDNIATRIQRAIRGRYLRRRYLQALKRIKKIQVIQHGFRLRRLVDYELKW-RLFIKLQPLLSLLGSRKEYRSYLA 817

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081 1084 AATVIQatfrmhgaYMRYQHLKRASVVIQVhtaaelqRQKHAAVILQAAVRGMKTRSHLKTMHSSATLIQSQFRAFIVRR 1163
Cdd:COG5022   818 CIIKLQ--------KTIKREKKLRETEEVE-------FSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAER 882


                  ....*....
gi 568908081 1164 RFIALRKAA 1172
Cdd:COG5022   883 QLQELKIDV 891
COG5022 COG5022
Myosin heavy chain [General function prediction only];
41-198 1.02e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 50.85  E-value: 1.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081   41 KAARVIQSVVLNFLSRRRLQ--KNVSAALVIQKCWR----------RVSAQRKL-RMLKNEKLA------KLQNKSAVLI 101
Cdd:COG5022   769 KRIKKIQVIQHGFRLRRLVDyeLKWRLFIKLQPLLSllgsrkeyrsYLACIIKLqKTIKREKKLreteevEFSLKAEVLI 848

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  102 QAYWRRYSTRKRFLRLKHYSVILQSRIRMKIALTSYKRYLWATVTIQRhwRAYLSRKRDQQIFRKLK--SSSLVIQFMFR 179
Cdd:COG5022   849 QKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSISS--LKLVNLELESEIIELKKslSSDLIENLEFK 926

                         170       180
                  ....*....|....*....|....
gi 568908081  180 -----RWKRRKLQLQTKAAVTLQR 198
Cdd:COG5022   927 teliaRLKKLLNNIDLEEGPSIEY 950
COG5022 COG5022
Myosin heavy chain [General function prediction only];
372-518 5.39e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.54  E-value: 5.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  372 VLASYQKTRS-----SVIVLQSACRGMQARKAFRHALASVIKIQSYYRAYICRKTFQNFK--NATIKLQSIVKMKQSRKQ 444
Cdd:COG5022   732 VLAALEDMRDakldnIATRIQRAIRGRYLRRRYLQALKRIKKIQVIQHGFRLRRLVDYELkwRLFIKLQPLLSLLGSRKE 811

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568908081  445 YLQIRAAALFIQRWYRSQKLASQKRKEYIQVRESCIKlQSHFRGCLVRKQLRLQCKAAISLQSYFRMRTARQRY 518
Cdd:COG5022   812 YRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLI-QKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQL 884
COG5022 COG5022
Myosin heavy chain [General function prediction only];
979-1300 3.44e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.84  E-value: 3.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  979 EFQRYSRLRRSVLLIQAAFRGLRTR-RHLKAMHL--AATLIQRRFRTFAMRRKFLSLRKtAIWIQRQYRARLYAKYSRQq 1055
Cdd:COG5022   737 EDMRDAKLDNIATRIQRAIRGRYLRrRYLQALKRikKIQVIQHGFRLRRLVDYELKWRL-FIKLQPLLSLLGSRKEYRS- 814

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081 1056 llLEKAVIKIQ-SSYRGWVVRKRVQK--MHRAATVIQATFRMHGAYMRYQHLKRASVVIQvhTAAELQRQKHAAVILQAA 1132
Cdd:COG5022   815 --YLACIIKLQkTIKREKKLRETEEVefSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQ--SAQRVELAERQLQELKID 890

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081 1133 VRgmktrshlKTMHSSATLIQSQFRAFIVRRRFialrKAAIFVQRKFRATLYAKHKLHqflqLRKAAITIQSS--YRRLM 1210
Cdd:COG5022   891 VK--------SISSLKLVNLELESEIIELKKSL----SSDLIENLEFKTELIARLKKL----LNNIDLEEGPSieYVKLP 954

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081 1211 VQKKLQE----MHRAAALIQATFRMHRTYVAFHIWKCASIRI-QQCYRTYRTIK--LQKE-KLIREEQHSAAVLIQSTYR 1282
Cdd:COG5022   955 ELNKLHEveskLKETSEEYEDLLKKSTILVREGNKANSELKNfKKELAELSKQYgaLQEStKQLKELPVEVAELQSASKI 1034

                         330
                  ....*....|....*...
gi 568908081 1283 MYRQRCFYQQRRWAAKVI 1300
Cdd:COG5022  1035 ISSESTELSILKPLQKLK 1052
COG5022 COG5022
Myosin heavy chain [General function prediction only];
359-496 4.18e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.45  E-value: 4.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  359 IQTHFRASISARRvlasYQKTRSSVIVLQSACRGMQARKAFRHALAS--VIKIQSYYRAYICRKTFQNFKNATIKLQ-SI 435
Cdd:COG5022   751 IQRAIRGRYLRRR----YLQALKRIKKIQVIQHGFRLRRLVDYELKWrlFIKLQPLLSLLGSRKEYRSYLACIIKLQkTI 826

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568908081  436 VKMKQSRKQYLQIRA--AALFIQRWYRSqklaSQKRKEYIQVRESCIKLQSHFRGCLVRKQLR 496
Cdd:COG5022   827 KREKKLRETEEVEFSlkAEVLIQKFGRS----LKAKKRFSLLKKETIYLQSAQRVELAERQLQ 885
COG5022 COG5022
Myosin heavy chain [General function prediction only];
694-825 4.25e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.45  E-value: 4.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  694 LRHAALVFQAAWKGKMLRRQIARQHQCAALIQSY-----YRMHIQRRKWSimkTAALQIQLCYRAYkvgkEQRHLYLKTK 768
Cdd:COG5022   744 LDNIATRIQRAIRGRYLRRRYLQALKRIKKIQVIqhgfrLRRLVDYELKW---RLFIKLQPLLSLL----GSRKEYRSYL 816

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  769 AAVVTLQ-SAYRGMKVRKRVAEC--HKAAVTIQSKFRAYRTQKKYTTYRTSAIVIQRWYR 825
Cdd:COG5022   817 ACIIKLQkTIKREKKLRETEEVEfsLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQR 876
COG5022 COG5022
Myosin heavy chain [General function prediction only];
475-666 1.00e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.30  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  475 VRESCIKLQSHFRGCLVRKQ-LRLQC--KAAISLQSYFRMRTARQRYLKMcKAALVIQSFYCAYraqiSQRKNFLQVKRA 551
Cdd:COG5022   744 LDNIATRIQRAIRGRYLRRRyLQALKriKKIQVIQHGFRLRRLVDYELKW-RLFIKLQPLLSLL----GSRKEYRSYLAC 818

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  552 AICLQaayrgCKVRRQIKQQSTAAVtiqrvfrghsqrmkyQTMLQSAVKIQRWYRAQKVaydmRIQFLKTREAVVCLQSA 631
Cdd:COG5022   819 IIKLQ-----KTIKREKKLRETEEV---------------EFSLKAEVLIQKFGRSLKA----KKRFSLLKKETIYLQSA 874

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 568908081  632 YRGWQVRQQLRRQHEAAVKIQStfrmaVAQQQYKL 666
Cdd:COG5022   875 QRVELAERQLQELKIDVKSISS-----LKLVNLEL 904
COG5022 COG5022
Myosin heavy chain [General function prediction only];
46-195 1.01e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.30  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081   46 IQSVVLNFLSRRRLQKNVSAALVIQKCWRR----------VSAQRKLRMLKN----EKLAKLQNKS--AVLIQAYWRRYS 109
Cdd:COG5022   728 FKAGVLAALEDMRDAKLDNIATRIQRAIRGrylrrrylqaLKRIKKIQVIQHgfrlRRLVDYELKWrlFIKLQPLLSLLG 807

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  110 TRKRFLRLKHYSVILQSRIRMKIALTSY---KRYLWATVTIQRHWRAYLSRKRdqqiFRKLKSSSLVIQFMFRRWKRRKL 186
Cdd:COG5022   808 SRKEYRSYLACIIKLQKTIKREKKLRETeevEFSLKAEVLIQKFGRSLKAKKR----FSLLKKETIYLQSAQRVELAERQ 883


                  ....*....
gi 568908081  187 QLQTKAAVT 195
Cdd:COG5022   884 LQELKIDVK 892
COG5022 COG5022
Myosin heavy chain [General function prediction only];
540-687 3.00e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 42.76  E-value: 3.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568908081  540 SQRKNFLQvkRAAICLQAAYRGCKVRRQIKQQSTAAVTIQRVFRG--HSQRMKYQTMLQSAVKIQR-----WYRAQKVAY 612
Cdd:COG5022   738 DMRDAKLD--NIATRIQRAIRGRYLRRRYLQALKRIKKIQVIQHGfrLRRLVDYELKWRLFIKLQPllsllGSRKEYRSY 815

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568908081  613 DMRIQFLKtreavvclQSAYRGWQVRQQLR--RQHEAAVKIQSTFRMAVAQQQYKLLRAAAAVIQQHVRARAAGKRQ 687
Cdd:COG5022   816 LACIIKLQ--------KTIKREKKLRETEEveFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQL 884
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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