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Conserved domains on  [gi|569010395|ref|XP_006528223|]
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zinc finger MYM-type protein 3 isoform X1 [Mus musculus]

Protein Classification

zf-FCS and DUF3504 domain-containing protein( domain architecture ID 13363461)

protein containing domains PHA03307, TRASH, zf-FCS, and DUF3504

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1229-1396 4.08e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


:

Pssm-ID: 463430  Cd Length: 162  Bit Score: 268.75  E-value: 4.08e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  1229 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1308
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  1309 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1385
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 569010395  1386 MLESMLNRILA 1396
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 39-349 9.77e-10

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 63.65  E-value: 9.77e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395   39 GPYPAMDPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPG 114
Cdd:PHA03307   60 AACDRFEPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  115 GVLDGATELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDS 192
Cdd:PHA03307  140 PVGSPGPPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASA 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  193 PIILESPHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPT 259
Cdd:PHA03307  218 SSPAPAPGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPS 297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  260 AHPSLPGDGLTgkeieKPPERVQKRSERVRRAEPPKP---EVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMS 336
Cdd:PHA03307  298 PSPSSPGSGPA-----PSSPRASSSSSSSRESSSSSTsssSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPS 372

                         330
                  ....*....|....
gi 569010395  337 LR-SSMAQRAGRSS 349
Cdd:PHA03307  373 RApSSPAASAGRPT 386
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 538-577 4.03e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.75  E-value: 4.03e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   538 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 577
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 393-434 3.07e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 3.07e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 569010395   393 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 434
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 631-668 1.02e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 1.02e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   631 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 668
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 491-533 1.80e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.13  E-value: 1.80e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 569010395   491 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 533
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 719-755 2.27e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.27e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   719 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 755
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 760-796 1.69e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.43  E-value: 1.69e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   760 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 796
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 586-623 7.45e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.51  E-value: 7.45e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   586 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 623
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 673-709 1.67e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.67e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   673 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 709
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
356-392 3.79e-03

metallochaperone-like domain;


:

Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.59  E-value: 3.79e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010395    356 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 392
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 449-485 4.14e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.14e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   449 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 485
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1229-1396 4.08e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 268.75  E-value: 4.08e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  1229 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1308
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  1309 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1385
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 569010395  1386 MLESMLNRILA 1396
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 39-349 9.77e-10

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 63.65  E-value: 9.77e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395   39 GPYPAMDPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPG 114
Cdd:PHA03307   60 AACDRFEPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  115 GVLDGATELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDS 192
Cdd:PHA03307  140 PVGSPGPPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASA 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  193 PIILESPHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPT 259
Cdd:PHA03307  218 SSPAPAPGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPS 297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  260 AHPSLPGDGLTgkeieKPPERVQKRSERVRRAEPPKP---EVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMS 336
Cdd:PHA03307  298 PSPSSPGSGPA-----PSSPRASSSSSSSRESSSSSTsssSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPS 372

                         330
                  ....*....|....
gi 569010395  337 LR-SSMAQRAGRSS 349
Cdd:PHA03307  373 RApSSPAASAGRPT 386
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 538-577 4.03e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.75  E-value: 4.03e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   538 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 577
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 393-434 3.07e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 3.07e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 569010395   393 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 434
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 631-668 1.02e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 1.02e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   631 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 668
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 491-533 1.80e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.13  E-value: 1.80e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 569010395   491 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 533
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 719-755 2.27e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.27e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   719 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 755
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
543-581 5.20e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 41.59  E-value: 5.20e-05
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010395    543 CVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQ 581
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 760-796 1.69e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.43  E-value: 1.69e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   760 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 796
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
496-537 2.00e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 40.05  E-value: 2.00e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 569010395    496 CDQCGAYIYaRPGGlgPELLFHDGQQKRFCNTTCLGAYKKKN 537
Cdd:smart00746    1 CSFCGKDIY-NPGT--GIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
636-672 2.44e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 2.44e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010395    636 CHYCHSLFS--GKPEVLEWQDQVFQFCCRDCCEDFKRLR 672
Cdd:smart00746    1 CSFCGKDIYnpGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 586-623 7.45e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.51  E-value: 7.45e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   586 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 623
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
724-756 8.17e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.13  E-value: 8.17e-04
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 569010395    724 CTYCSQTCQRGVTE---QLDGSTWDFCSEDCKTKYL 756
Cdd:smart00746    1 CSFCGKDIYNPGTGimvVNDGKVYYFCSSKCLSKFK 36
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 673-709 1.67e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.67e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   673 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 709
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
356-392 3.79e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.59  E-value: 3.79e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010395    356 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 392
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 449-485 4.14e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.14e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   449 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 485
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
591-624 6.27e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.82  E-value: 6.27e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 569010395    591 CSFCRRSLSDPCYYNKV--DRTVYQFCSPSCWTKFQ 624
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVvnDGKVYYFCSSKCLSKFK 36
TRASH smart00746
metallochaperone-like domain;
765-800 8.26e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 8.26e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010395    765 CHACKRQGKLLETIH---WRGQIRHFCNQQCLLRFYSQQ 800
Cdd:smart00746    1 CSFCGKDIYNPGTGImvvNDGKVYYFCSSKCLSKFKKKR 39
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1229-1396 4.08e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 268.75  E-value: 4.08e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  1229 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1308
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  1309 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1385
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 569010395  1386 MLESMLNRILA 1396
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 39-349 9.77e-10

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 63.65  E-value: 9.77e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395   39 GPYPAMDPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPG 114
Cdd:PHA03307   60 AACDRFEPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  115 GVLDGATELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDS 192
Cdd:PHA03307  140 PVGSPGPPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASA 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  193 PIILESPHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPT 259
Cdd:PHA03307  218 SSPAPAPGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPS 297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  260 AHPSLPGDGLTgkeieKPPERVQKRSERVRRAEPPKP---EVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMS 336
Cdd:PHA03307  298 PSPSSPGSGPA-----PSSPRASSSSSSSRESSSSSTsssSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPS 372

                         330
                  ....*....|....
gi 569010395  337 LR-SSMAQRAGRSS 349
Cdd:PHA03307  373 RApSSPAASAGRPT 386
PHA03247 PHA03247
large tegument protein UL36; Provisional
 27-320 9.64e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.26  E-value: 9.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395   27 GVVTKPEPFNWQGPYPAMDPSDFPSPfDPLTLPEKPLAGDLPVdmefgedlLESQTAPSRGWAPPGP-SPSSGALDLLDT 105
Cdd:PHA03247 2753 GPARPARPPTTAGPPAPAPPAAPAAG-PPRRLTRPAVASLSES--------RESLPSPWDPADPPAAvLAPAAALPPAAS 2823

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  106 PSGLEKDPGGVLDGATEllglggllyKAPSPPEVDHGPEGTLAwdSGEQTLEPGPGCQTPEV--MPPDPGA---GASPPS 180
Cdd:PHA03247 2824 PAGPLPPPTSAQPTAPP---------PPPGPPPPSLPLGGSVA--PGGDVRRRPPSRSPAAKpaAPARPPVrrlARPAVS 2892

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  181 PEGLLEPLAPDSPIILESPHIEEEIPPLATRRRGSPGQEEEHTQGQPQSPNAPPSPSVGetlgdginSSQSKPGVCTPTA 260
Cdd:PHA03247 2893 RSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAG--------AGEPSGAVPQPWL 2964

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  261 HPSLPGdgltgkEIEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPN 320
Cdd:PHA03247 2965 GALVPG------RVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETD 3018
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 76-349 2.90e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 55.56  E-value: 2.90e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395   76 DLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGVLDG----ATELLGLGGLLYKAPSPPEVDHGPEGTLAWDS 151
Cdd:PHA03307    9 DLIEAAAEGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAAvtvvAGAAACDRFEPPTGPPPGPGTEAPANESRSTP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  152 G--EQTLEPGPGCQTPEVMPPDPGAGASPPSPEGLLEPLAPDSPIILESPHIEEEIPPLATRRR----GSPGQEEEHTQG 225
Cdd:PHA03307   89 TwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPpaagASPAAVASDAAS 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  226 QPQSpnAPPSPSVGETLGDGINSSQSKPGVCTPTAHPslPGDGLTGKEIEKPPERVQKRSERVRRAEPPKPEVVDSTESI 305
Cdd:PHA03307  169 SRQA--ALPLSSPEETARAPSSPPAEPPPSTPPAAAS--PRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSES 244

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 569010395  306 PVSDEDSDAMVDDPNDEDFV-PFRPRRSPRMSLRSSMAQRAGRSS 349
Cdd:PHA03307  245 SGCGWGPENECPLPRPAPITlPTRIWEASGWNGPSSRPGPASSSS 289
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 538-577 4.03e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.75  E-value: 4.03e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   538 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 577
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 393-434 3.07e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 3.07e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 569010395   393 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 434
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 631-668 1.02e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 1.02e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   631 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 668
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 491-533 1.80e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.13  E-value: 1.80e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 569010395   491 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 533
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 719-755 2.27e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.27e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   719 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 755
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
543-581 5.20e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 41.59  E-value: 5.20e-05
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010395    543 CVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQ 581
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
PHA03247 PHA03247
large tegument protein UL36; Provisional
 132-295 7.68e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 7.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  132 KAPSPPEVDHGPEGTLAWDSGEqtlEPGPGCQTPEVMPPDPGAGASPPSP----EGLLE-----------PLAPDSPiil 196
Cdd:PHA03247 2487 RFPFAAGAAPDPGGGGPPDPDA---PPAPSRLAPAILPDEPVGEPVHPRMltwiRGLEElasddagdpppPLPPAAP--- 2560

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  197 eSPHIEEEIPPlatrRRGSPGQEEEHTQGQPQSPNAPPSPSVGETLGDGINSS--QSKPGVCTPTAHPSLP--------G 266
Cdd:PHA03247 2561 -PAAPDRSVPP----PRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPrgPAPPSPLPPDTHAPDPpppspspaA 2635

                         170       180       190
                  ....*....|....*....|....*....|
gi 569010395  267 DGLTGKEIEKPPERVQKRSE-RVRRAEPPK 295
Cdd:PHA03247 2636 NEPDPHPPPTVPPPERPRDDpAPGRVSRPR 2665
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 760-796 1.69e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.43  E-value: 1.69e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   760 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 796
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
496-537 2.00e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 40.05  E-value: 2.00e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 569010395    496 CDQCGAYIYaRPGGlgPELLFHDGQQKRFCNTTCLGAYKKKN 537
Cdd:smart00746    1 CSFCGKDIY-NPGT--GIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
636-672 2.44e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 2.44e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010395    636 CHYCHSLFS--GKPEVLEWQDQVFQFCCRDCCEDFKRLR 672
Cdd:smart00746    1 CSFCGKDIYnpGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 586-623 7.45e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.51  E-value: 7.45e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   586 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 623
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
724-756 8.17e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.13  E-value: 8.17e-04
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 569010395    724 CTYCSQTCQRGVTE---QLDGSTWDFCSEDCKTKYL 756
Cdd:smart00746    1 CSFCGKDIYNPGTGimvVNDGKVYYFCSSKCLSKFK 36
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 142-333 1.28e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.44  E-value: 1.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  142 GPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPE----GLLEPLAPDSPIILESPHIEEEIPPLATRRRG-SP 216
Cdd:PRK07764  599 GPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEAsaapAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGaAP 678

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  217 GQEEEHTQGQPQSPN---APPSPSVGETLGDGINSSQSKPGVCTPTAHPSLPGDGLTGKEIEKPPE-RVQKRSERVRRAE 292
Cdd:PRK07764  679 AAPPPAPAPAAPAAPagaAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEpDDPPDPAGAPAQP 758

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 569010395  293 PPKPEVVD----STESIPVSDEDSDAMVDDpnDEDFVPFRPRRSP 333
Cdd:PRK07764  759 PPPPAPAPaaapAAAPPPSPPSEEEEMAED--DAPSMDDEDRRDA 801
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 673-709 1.67e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.67e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   673 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 709
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
356-392 3.79e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.59  E-value: 3.79e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010395    356 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 392
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 449-485 4.14e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.14e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010395   449 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 485
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
PHA03247 PHA03247
large tegument protein UL36; Provisional
 83-303 5.99e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 5.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395   83 APSRGWAPPGPSPSSGAldlldtPSGLEKDPGGVLDGATELLGLGGLLYKAPSPPEVDHGPEGTlawDSGEQTLE----- 157
Cdd:PHA03247  270 ETARGATGPPPPPEAAA------PNGAAAPPDGVWGAALAGAPLALPAPPDPPPPAPAGDAEEE---DDEDGAMEvvspl 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  158 PGPGCQTPEVMPPDPGAGASPPSPeglLEPLAPDspiileSPHIEEEIPPLATRR----------RGSPGQEEEH----T 223
Cdd:PHA03247  341 PRPRQHYPLGFPKRRRPTWTPPSS---LEDLSAG------RHHPKRASLPTRKRRsarhaatpfaRGPGGDDQTRpaapV 411

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010395  224 QGQPQSPNAPPSPSVGETLGDGINSSQSKPGVCTPTAHPS-LPGDGLTGKEIEKPPERVQKRSERVRRAEPPKPEVVDST 302
Cdd:PHA03247  412 PASVPTPAPTPVPASAPPPPATPLPSAEPGSDDGPAPPPErQPPAPATEPAPDDPDDATRKALDALRERRPPEPPGADLA 491


                  .
gi 569010395  303 E 303
Cdd:PHA03247  492 E 492
TRASH smart00746
metallochaperone-like domain;
591-624 6.27e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.82  E-value: 6.27e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 569010395    591 CSFCRRSLSDPCYYNKV--DRTVYQFCSPSCWTKFQ 624
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVvnDGKVYYFCSSKCLSKFK 36
TRASH smart00746
metallochaperone-like domain;
765-800 8.26e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 8.26e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010395    765 CHACKRQGKLLETIH---WRGQIRHFCNQQCLLRFYSQQ 800
Cdd:smart00746    1 CSFCGKDIYNPGTGImvvNDGKVYYFCSSKCLSKFKKKR 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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