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Conserved domains on  [gi|569009735|ref|XP_006527898|]
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host cell factor 1 isoform X1 [Mus musculus]

Protein Classification

Kelch_5 and FN3 domain-containing protein( domain architecture ID 13287381)

protein containing domains PLN02193, Kelch_5, SP1-4_N, and FN3

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
25-344 1.18e-21

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 97.15  E-value: 1.18e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   25 WS--GPVPRPRHGHRAVAIKELIVVFGGGNEG-IVDELHVYNTATNQWfipaVRGDIPPGCAAYGFVC--DGTRLLVFGG 99
Cdd:COG3055     3 WSslPDLPTPRSEAAAALLDGKVYVAGGLSGGsASNSFEVYDPATNTW----SELAPLPGPPRHHAAAvaQDGKLYVFGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  100 MVEY---GKYSNDLYELQASRWEWKRLkaktpknGPPPCPRLGHSFSLVGNKCYLFGGlandsedpkNNIPRYLNDLYIL 176
Cdd:COG3055    79 FTGAnpsSTPLNDVYVYDPATNTWTKL-------APMPTPRGGATALLLDGKIYVVGG---------WDDGGNVAWVEVY 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  177 ELRPGSgvvaWDipiTYGVLPPPRESHTAVVYTEkdnkkSKLVIYGGMSGCRLGDLWTldietltwNKPSLsgvaPLPRS 256
Cdd:COG3055   143 DPATGT----WT---QLAPLPTPRDHLAAAVLPD-----GKILVIGGRNGSGFSNTWT--------TLAPL----PTARA 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  257 LHSATTIGNKMYVFGGwvplvmddvkvathekEWKCTNTLACLNLDTMAWETIlmdtleDNIPRARAGHCAVAINTRLYI 336
Cdd:COG3055   199 GHAAAVLGGKILVFGG----------------ESGFSDEVEAYDPATNTWTAL------GELPTPRHGHAAVLTDGKVYV 256

                         330
                  ....*....|
gi 569009735  337 WSG--RDGYR 344
Cdd:COG3055   257 IGGetKPGVR 266
COG4625 super family cl34793
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 444-950 3.58e-03

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


The actual alignment was detected with superfamily member COG4625:

Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 42.46  E-value: 3.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  444 GITLVPQAATAPPSTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPASV 523
Cdd:COG4625     1 GGGGGGGGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  524 RMVVPTQSAQGTVIGSNPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTVAVTPGTTTLPATVKVASSPVMVS 603
Cdd:COG4625    81 GGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  604 NPATRMLKTAAAQVGTSVSSAANTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTIT-LVKSPISVPGGSALISNLGK 682
Cdd:COG4625   161 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGgGGGGGGGGGGGGGGGGGGGG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  683 VMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTK 762
Cdd:COG4625   241 GGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  763 PGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842
Cdd:COG4625   321 GGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGG 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  843 GT-ILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGAHSTSASLATPITTLGTIATLSS 921
Cdd:COG4625   401 GGgGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTG 480

                         490       500
                  ....*....|....*....|....*....
gi 569009735  922 QVINPTAITVSAAQTTLTAAGGLTTPTIT 950
Cdd:COG4625   481 NNTYTGTTTVNGGGNYTQSAGSTLAVEVD 509
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1911-1940 3.76e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 3.76e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 569009735 1911 LQPGTAYKFRVAGINACGRGPFSEISAFKT 1940
Cdd:cd00063    64 LKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
25-344 1.18e-21

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 97.15  E-value: 1.18e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   25 WS--GPVPRPRHGHRAVAIKELIVVFGGGNEG-IVDELHVYNTATNQWfipaVRGDIPPGCAAYGFVC--DGTRLLVFGG 99
Cdd:COG3055     3 WSslPDLPTPRSEAAAALLDGKVYVAGGLSGGsASNSFEVYDPATNTW----SELAPLPGPPRHHAAAvaQDGKLYVFGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  100 MVEY---GKYSNDLYELQASRWEWKRLkaktpknGPPPCPRLGHSFSLVGNKCYLFGGlandsedpkNNIPRYLNDLYIL 176
Cdd:COG3055    79 FTGAnpsSTPLNDVYVYDPATNTWTKL-------APMPTPRGGATALLLDGKIYVVGG---------WDDGGNVAWVEVY 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  177 ELRPGSgvvaWDipiTYGVLPPPRESHTAVVYTEkdnkkSKLVIYGGMSGCRLGDLWTldietltwNKPSLsgvaPLPRS 256
Cdd:COG3055   143 DPATGT----WT---QLAPLPTPRDHLAAAVLPD-----GKILVIGGRNGSGFSNTWT--------TLAPL----PTARA 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  257 LHSATTIGNKMYVFGGwvplvmddvkvathekEWKCTNTLACLNLDTMAWETIlmdtleDNIPRARAGHCAVAINTRLYI 336
Cdd:COG3055   199 GHAAAVLGGKILVFGG----------------ESGFSDEVEAYDPATNTWTAL------GELPTPRHGHAAVLTDGKVYV 256

                         330
                  ....*....|
gi 569009735  337 WSG--RDGYR 344
Cdd:COG3055   257 IGGetKPGVR 266
PLN02193 PLN02193
nitrile-specifier protein
 27-322 3.99e-16

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 83.47  E-value: 3.99e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   27 GPVPRPRHGHRAVAIKelIVVFGGG---NEGIVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGFVCDGTRLLVFGGMVE 102
Cdd:PLN02193  162 GPGLRCSHGIAQVGNK--IYSFGGEftpNQPIDKHLYVFDLETRTWSISPATGDVPHlSCLGVRMVSIGSTLYVFGGRDA 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  103 YGKYsNDLYELQASRWEWKRLkakTP-KNGppPCPRLGHSFSLVGNKCYLFGGLANDSEdpknniPRYLNDLYILELRpg 181
Cdd:PLN02193  240 SRQY-NGFYSFDTTTNEWKLL---TPvEEG--PTPRSFHSMAADEENVYVFGGVSATAR------LKTLDSYNIVDKK-- 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  182 sgvvaWDIPITygvlppPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIETLTWNKPSLSGVAPLPRSLHSAT 261
Cdd:PLN02193  306 -----WFHCST------PGDSFSIRGGAGLEVVQGKVWVVYGFNGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASA 374

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 569009735  262 TIGNKMYVFGGwvPLVMDDVkvaTHEKEWKCTNTLACLNLDTMAWETILMDTLEDNIPRAR 322
Cdd:PLN02193  375 AVGKHIVIFGG--EIAMDPL---AHVGPGQLTDGTFALDTETLQWERLDKFGEEEETPSSR 430
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 32-69 8.11e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 41.83  E-value: 8.11e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 569009735    32 PRHGHRAVAIKELIVVFGGGNEG-IVDELHVYNTATNQW 69
Cdd:pfam01344    1 RRSGAGVVVVGGKIYVIGGFDGNqSLNSVEVYDPETNTW 39
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 444-950 3.58e-03

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 42.46  E-value: 3.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  444 GITLVPQAATAPPSTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPASV 523
Cdd:COG4625     1 GGGGGGGGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  524 RMVVPTQSAQGTVIGSNPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTVAVTPGTTTLPATVKVASSPVMVS 603
Cdd:COG4625    81 GGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  604 NPATRMLKTAAAQVGTSVSSAANTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTIT-LVKSPISVPGGSALISNLGK 682
Cdd:COG4625   161 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGgGGGGGGGGGGGGGGGGGGGG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  683 VMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTK 762
Cdd:COG4625   241 GGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  763 PGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842
Cdd:COG4625   321 GGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGG 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  843 GT-ILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGAHSTSASLATPITTLGTIATLSS 921
Cdd:COG4625   401 GGgGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTG 480

                         490       500
                  ....*....|....*....|....*....
gi 569009735  922 QVINPTAITVSAAQTTLTAAGGLTTPTIT 950
Cdd:COG4625   481 NNTYTGTTTVNGGGNYTQSAGSTLAVEVD 509
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1911-1940 3.76e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 3.76e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 569009735 1911 LQPGTAYKFRVAGINACGRGPFSEISAFKT 1940
Cdd:cd00063    64 LKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 441-771 7.49e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.44  E-value: 7.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   441 TQVGITLVPQAATAPPSTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTgPQATTGTPLVTMRPASQAGKAPVTVTSLP 520
Cdd:pfam05109  510 TSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPT-PAVTTPTPNATIPTLGKTSPTSAVTTPTP 588

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   521 ASVRMVVPTQSAQGTVigSNPQMSGMaalaaaaaatqkippSSAPTVLSVPAGTtivkTVAVTPGTTTLPATvkvasspv 600
Cdd:pfam05109  589 NATSPTVGETSPQANT--TNHTLGGT---------------SSTPVVTSPPKNA----TSAVTTGQHNITSS-------- 639

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   601 mvSNPATRMLKTAAAQVGTSVSSAANTSTRPIIT-VHKSGTVTVAQQAQVVTTVVGGVTktitlvKSPISVPGGSALISN 679
Cdd:pfam05109  640 --STSSMSLRPSSISETLSPSTSDNSTSHMPLLTsAHPTGGENITQVTPASTSTHHVST------SSPAPRPGTTSQASG 711

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   680 LGKvmSVVQTKPVQTSAVTGQastgPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKptilgiSSVSPS 759
Cdd:pfam05109  712 PGN--SSTSTKPGEVNVTKGT----PPKNATSPQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHGAR------TSTEPT 779

                          330
                   ....*....|..
gi 569009735   760 TTKPGTTTIIKT 771
Cdd:pfam05109  780 TDYGGDSTTPRT 791
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
25-344 1.18e-21

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 97.15  E-value: 1.18e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   25 WS--GPVPRPRHGHRAVAIKELIVVFGGGNEG-IVDELHVYNTATNQWfipaVRGDIPPGCAAYGFVC--DGTRLLVFGG 99
Cdd:COG3055     3 WSslPDLPTPRSEAAAALLDGKVYVAGGLSGGsASNSFEVYDPATNTW----SELAPLPGPPRHHAAAvaQDGKLYVFGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  100 MVEY---GKYSNDLYELQASRWEWKRLkaktpknGPPPCPRLGHSFSLVGNKCYLFGGlandsedpkNNIPRYLNDLYIL 176
Cdd:COG3055    79 FTGAnpsSTPLNDVYVYDPATNTWTKL-------APMPTPRGGATALLLDGKIYVVGG---------WDDGGNVAWVEVY 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  177 ELRPGSgvvaWDipiTYGVLPPPRESHTAVVYTEkdnkkSKLVIYGGMSGCRLGDLWTldietltwNKPSLsgvaPLPRS 256
Cdd:COG3055   143 DPATGT----WT---QLAPLPTPRDHLAAAVLPD-----GKILVIGGRNGSGFSNTWT--------TLAPL----PTARA 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  257 LHSATTIGNKMYVFGGwvplvmddvkvathekEWKCTNTLACLNLDTMAWETIlmdtleDNIPRARAGHCAVAINTRLYI 336
Cdd:COG3055   199 GHAAAVLGGKILVFGG----------------ESGFSDEVEAYDPATNTWTAL------GELPTPRHGHAAVLTDGKVYV 256

                         330
                  ....*....|
gi 569009735  337 WSG--RDGYR 344
Cdd:COG3055   257 IGGetKPGVR 266
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
76-345 6.14e-17

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 83.28  E-value: 6.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   76 GDIP-PGCAAYGFVCDGtRLLVFGGMvEYGKYSNDLYELQASRWEWKRLkaktpknGPPPCPRLGHSFSLV-GNKCYLFG 153
Cdd:COG3055     7 PDLPtPRSEAAAALLDG-KVYVAGGL-SGGSASNSFEVYDPATNTWSEL-------APLPGPPRHHAAAVAqDGKLYVFG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  154 GLandseDPKNNIPRYLNDLYILELRPGSgvvaWdipITYGVLPPPRESHTAVVYtekDNKKskLVIYGGMSGCRLGDLW 233
Cdd:COG3055    78 GF-----TGANPSSTPLNDVYVYDPATNT----W---TKLAPMPTPRGGATALLL---DGKI--YVVGGWDDGGNVAWVE 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  234 TLDIETLTWNKPslsGVAPLPRSLHSATTIGN-KMYVFGGwvplvmddVKVATHEKEWkctntlaclnldtmawetilmd 312
Cdd:COG3055   141 VYDPATGTWTQL---APLPTPRDHLAAAVLPDgKILVIGG--------RNGSGFSNTW---------------------- 187

                         250       260       270
                  ....*....|....*....|....*....|...
gi 569009735  313 TLEDNIPRARAGHCAVAINTRLYIWSGRDGYRK 345
Cdd:COG3055   188 TTLAPLPTARAGHAAAVLGGKILVFGGESGFSD 220
PLN02193 PLN02193
nitrile-specifier protein
 27-322 3.99e-16

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 83.47  E-value: 3.99e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   27 GPVPRPRHGHRAVAIKelIVVFGGG---NEGIVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGFVCDGTRLLVFGGMVE 102
Cdd:PLN02193  162 GPGLRCSHGIAQVGNK--IYSFGGEftpNQPIDKHLYVFDLETRTWSISPATGDVPHlSCLGVRMVSIGSTLYVFGGRDA 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  103 YGKYsNDLYELQASRWEWKRLkakTP-KNGppPCPRLGHSFSLVGNKCYLFGGLANDSEdpknniPRYLNDLYILELRpg 181
Cdd:PLN02193  240 SRQY-NGFYSFDTTTNEWKLL---TPvEEG--PTPRSFHSMAADEENVYVFGGVSATAR------LKTLDSYNIVDKK-- 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  182 sgvvaWDIPITygvlppPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIETLTWNKPSLSGVAPLPRSLHSAT 261
Cdd:PLN02193  306 -----WFHCST------PGDSFSIRGGAGLEVVQGKVWVVYGFNGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASA 374

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 569009735  262 TIGNKMYVFGGwvPLVMDDVkvaTHEKEWKCTNTLACLNLDTMAWETILMDTLEDNIPRAR 322
Cdd:PLN02193  375 AVGKHIVIFGG--EIAMDPL---AHVGPGQLTDGTFALDTETLQWERLDKFGEEEETPSSR 430
PLN02153 PLN02153
epithiospecifier protein
 12-330 2.66e-15

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 79.65  E-value: 2.66e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   12 AVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGG---NEGIVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGF 87
Cdd:PLN02153    2 APTLQGGWIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGGElkpNEHIDKDLYVFDFNTHTWSIAPANGDVPRiSCLGVRM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   88 VCDGTRLLVFGGMVEYGKYsNDLYELQASRWEWKRLKAKTPKNGPPpcPRLGHSFSLVGNKCYLFGGLANDS-------- 159
Cdd:PLN02153   82 VAVGTKLYIFGGRDEKREF-SDFYSYDTVKNEWTFLTKLDEEGGPE--ARTFHSMASDENHVYVFGGVSKGGlmktperf 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  160 ----------------EDPKNNiprylndlyiLELRPGSG--VVAWDIPITYGVLpppreshTAVVYTEKDNKKSKLVIY 221
Cdd:PLN02153  159 rtieayniadgkwvqlPDPGEN----------FEKRGGAGfaVVQGKIWVVYGFA-------TSILPGGKSDYESNAVQF 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  222 ggmsgcrlgdlwtLDIETLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWvplVMDDVKvaTHEKEWKCTNTLACLNL 301
Cdd:PLN02153  222 -------------FDPASGKWTEVETTGAKPSARSVFAHAVVGKYIIIFGGE---VWPDLK--GHLGPGTLSNEGYALDT 283

                         330       340
                  ....*....|....*....|....*....
gi 569009735  302 DTMAWETiLMDTLEDNIPRARAGHCAVAI 330
Cdd:PLN02153  284 ETLVWEK-LGECGEPAMPRGWTAYTTATV 311
PLN02193 PLN02193
nitrile-specifier protein
 126-272 3.20e-08

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 58.43  E-value: 3.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  126 KTPKNGPPPCPRLGHSFSLVGNKCYLFGGlandSEDPKNNIPRYlndLYILELRPGSgvvaWDIPITYGVLPppresHTA 205
Cdd:PLN02193  155 KVEQKGEGPGLRCSHGIAQVGNKIYSFGG----EFTPNQPIDKH---LYVFDLETRT----WSISPATGDVP-----HLS 218

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 569009735  206 VVYTEKDNKKSKLVIYGGMSGCR-LGDLWTLDIETLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGG 272
Cdd:PLN02193  219 CLGVRMVSIGSTLYVFGGRDASRqYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGG 286
PRK14131 PRK14131
N-acetylneuraminate epimerase;
18-99 1.98e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 49.24  E-value: 1.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   18 RWKRVVGWSGPvprPRHGHRAVAIKELIVVFGG----GNEG---IVDELHVYNTATNQWFIPAVRGdiPPGCA-AYGFVC 89
Cdd:PRK14131   63 GWTKIAAFPGG---PREQAVAAFIDGKLYVFGGigktNSEGspqVFDDVYKYDPKTNSWQKLDTRS--PVGLAgHVAVSL 137

                          90
                  ....*....|
gi 569009735   90 DGTRLLVFGG 99
Cdd:PRK14131  138 HNGKAYITGG 147
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
27-114 4.96e-05

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 47.46  E-value: 4.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   27 GPVPRPRHGHRAVAIKELIVVFGGGNeGIVDELHVYNTATNQWFipaVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKY 106
Cdd:COG3055   191 APLPTARAGHAAAVLGGKILVFGGES-GFSDEVEAYDPATNTWT---ALGELPTPRHGHAAVLTDGKVYVIGGETKPGVR 266


                  ....*...
gi 569009735  107 SNDLYELQ 114
Cdd:COG3055   267 TPLVTSAE 274
PLN02193 PLN02193
nitrile-specifier protein
 242-393 7.77e-05

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 47.64  E-value: 7.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  242 WNKPSLSGVAPLPRSLHSATTIGNKMYVFGG-WVPlvmdDVKVATHekewkctntLACLNLDTMAWEtilMDTLEDNIPR 320
Cdd:PLN02193  153 WIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGeFTP----NQPIDKH---------LYVFDLETRTWS---ISPATGDVPH 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  321 ARA-GHCAVAINTRLYIWSGRDGYRK--AWNNQVCCKDLWYLET--EKPPPPARVQLVRANTNSLEVSWGAVATA----- 390
Cdd:PLN02193  217 LSClGVRMVSIGSTLYVFGGRDASRQynGFYSFDTTTNEWKLLTpvEEGPTPRSFHSMAADEENVYVFGGVSATArlktl 296


                  ...
gi 569009735  391 DSY 393
Cdd:PLN02193  297 DSY 299
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 32-69 8.11e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 41.83  E-value: 8.11e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 569009735    32 PRHGHRAVAIKELIVVFGGGNEG-IVDELHVYNTATNQW 69
Cdd:pfam01344    1 RRSGAGVVVVGGKIYVIGGFDGNqSLNSVEVYDPETNTW 39
Kelch_3 pfam13415
Galactose oxidase, central domain;
264-330 1.46e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 41.12  E-value: 1.46e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 569009735   264 GNKMYVFGGWVPLVMDdvkvathekewkCTNTLACLNLDTMAWETIlmdtleDNIPRARAGHCAVAI 330
Cdd:pfam13415    1 GDKLYIFGGLGFDGQT------------RLNDLYVYDLDTNTWTQI------GDLPPPRSGHSATYI 49
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
241-348 1.76e-04

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 45.53  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  241 TWNK-PSLsgvaPLPRSLHSATTIGNKMYVFGGWvplvmddvkvatheKEWKCTNTLACLNLDTMAWETIlmdtleDNIP 319
Cdd:COG3055     2 TWSSlPDL----PTPRSEAAAALLDGKVYVAGGL--------------SGGSASNSFEVYDPATNTWSEL------APLP 57

                          90       100       110
                  ....*....|....*....|....*....|
gi 569009735  320 RARAGH-CAVAINTRLYIWSGRDGYRKAWN 348
Cdd:COG3055    58 GPPRHHaAAVAQDGKLYVFGGFTGANPSST 87
Kelch_3 pfam13415
Galactose oxidase, central domain;
215-263 9.49e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 38.81  E-value: 9.49e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 569009735   215 KSKLVIYGG---MSGCRLGDLWTLDIETLTWNKPslsGVAPLPRSLHSATTI 263
Cdd:pfam13415    1 GDKLYIFGGlgfDGQTRLNDLYVYDLDTNTWTQI---GDLPPPRSGHSATYI 49
Kelch_4 pfam13418
Galactose oxidase, central domain;
32-80 1.37e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 38.36  E-value: 1.37e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 569009735    32 PRHGHRAVAIKE-LIVVFGG--GNEGIVDELHVYNTATNQWfipAVRGDIPP 80
Cdd:pfam13418    1 PRAYHTSTSIPDdTIYLFGGegEDGTLLSDLWVFDLSTNEW---TRLGSLPS 49
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 30-67 2.67e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 37.54  E-value: 2.67e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 569009735    30 PRPRHGHRAVAIKELIVVFGG---GNEGIVDELHVYNTATN 67
Cdd:pfam13854    1 PVPRYGHCAVTVGDYIYLYGGytgGEGQPSDDVYVLSLPTF 41
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 319-351 2.86e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 37.16  E-value: 2.86e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 569009735   319 PRARAGHCAVAINTRLYIWSGRDGYRKAWNNQV 351
Cdd:pfam13854    1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQPSDDV 33
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 444-950 3.58e-03

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 42.46  E-value: 3.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  444 GITLVPQAATAPPSTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPASV 523
Cdd:COG4625     1 GGGGGGGGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  524 RMVVPTQSAQGTVIGSNPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTVAVTPGTTTLPATVKVASSPVMVS 603
Cdd:COG4625    81 GGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  604 NPATRMLKTAAAQVGTSVSSAANTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTIT-LVKSPISVPGGSALISNLGK 682
Cdd:COG4625   161 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGgGGGGGGGGGGGGGGGGGGGG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  683 VMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTK 762
Cdd:COG4625   241 GGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  763 PGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842
Cdd:COG4625   321 GGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGG 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  843 GT-ILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGAHSTSASLATPITTLGTIATLSS 921
Cdd:COG4625   401 GGgGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTG 480

                         490       500
                  ....*....|....*....|....*....
gi 569009735  922 QVINPTAITVSAAQTTLTAAGGLTTPTIT 950
Cdd:COG4625   481 NNTYTGTTTVNGGGNYTQSAGSTLAVEVD 509
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1911-1940 3.76e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 3.76e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 569009735 1911 LQPGTAYKFRVAGINACGRGPFSEISAFKT 1940
Cdd:cd00063    64 LKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
PHA03098 PHA03098
kelch-like protein; Provisional
 38-295 6.41e-03

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 41.29  E-value: 6.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   38 AVAIKELIVVFGGGNEG--IVDELHVYNTATNQWF-IPavrgDIPPGCAAYGFVCDGTRLLVFGGmVEYGKYSNDLYELQ 114
Cdd:PHA03098  290 SVVLNNVIYFIGGMNKNnlSVNSVVSYDTKTKSWNkVP----ELIYPRKNPGVTVFNNRIYVIGG-IYNSISLNTVESWK 364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  115 ASRWEWKRLKaktpkngPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNnIPRYlnDLYILELRPGSGvvawdipityg 194
Cdd:PHA03098  365 PGESKWREEP-------PLIFPRYNPCVVNVNNLIYVIGGISKNDELLKT-VECF--SLNTNKWSKGSP----------- 423

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735  195 vLPPPRESHTAVVYtekdnkKSKLVIYGGMS----GCRLGDLWTLDIETLTWNKPSLSGVaplPRSLHSATTIGNKMYVF 270
Cdd:PHA03098  424 -LPISHYGGCAIYH------DGKIYVIGGISyidnIKVYNIVESYNPVTNKWTELSSLNF---PRINASLCIFNNKIYVV 493

                         250       260
                  ....*....|....*....|....*
gi 569009735  271 GGWvplvMDDVKVATHEKEWKCTNT 295
Cdd:PHA03098  494 GGD----KYEYYINEIEVYDDKTNT 514
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 441-771 7.49e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.44  E-value: 7.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   441 TQVGITLVPQAATAPPSTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTgPQATTGTPLVTMRPASQAGKAPVTVTSLP 520
Cdd:pfam05109  510 TSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPT-PAVTTPTPNATIPTLGKTSPTSAVTTPTP 588

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   521 ASVRMVVPTQSAQGTVigSNPQMSGMaalaaaaaatqkippSSAPTVLSVPAGTtivkTVAVTPGTTTLPATvkvasspv 600
Cdd:pfam05109  589 NATSPTVGETSPQANT--TNHTLGGT---------------SSTPVVTSPPKNA----TSAVTTGQHNITSS-------- 639

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   601 mvSNPATRMLKTAAAQVGTSVSSAANTSTRPIIT-VHKSGTVTVAQQAQVVTTVVGGVTktitlvKSPISVPGGSALISN 679
Cdd:pfam05109  640 --STSSMSLRPSSISETLSPSTSDNSTSHMPLLTsAHPTGGENITQVTPASTSTHHVST------SSPAPRPGTTSQASG 711

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009735   680 LGKvmSVVQTKPVQTSAVTGQastgPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKptilgiSSVSPS 759
Cdd:pfam05109  712 PGN--SSTSTKPGEVNVTKGT----PPKNATSPQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHGAR------TSTEPT 779

                          330
                   ....*....|..
gi 569009735   760 TTKPGTTTIIKT 771
Cdd:pfam05109  780 TDYGGDSTTPRT 791
Kelch_4 pfam13418
Galactose oxidase, central domain;
199-254 9.38e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 36.05  E-value: 9.38e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 569009735   199 PRESHTAVVytekdNKKSKLVIYGGMS--GCRLGDLWTLDIETLTWNKpslsgVAPLP 254
Cdd:pfam13418    1 PRAYHTSTS-----IPDDTIYLFGGEGedGTLLSDLWVFDLSTNEWTR-----LGSLP 48
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 254-273 9.89e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 36.05  E-value: 9.89e-03
                           10        20
                   ....*....|....*....|
gi 569009735   254 PRSLHSATTIGNKMYVFGGW 273
Cdd:pfam01344    1 RRSGAGVVVVGGKIYVIGGF 20
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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